cssi/SciSciGPT-SciSciNet huggingface dataset:
Management of Retrograde Peri-Implantitis Using an Air-Abrasive Device, Er,Cr:YSGG Laser, and Guided Bone Regeneration.

Background. The placement of an implant in a previously infected site is an important etiologic factor contributing to implant failure. The aim of this case report is to present the management of retrograde peri-implantitis (RPI) in a first maxillary molar site, 2 years after the implant placement. The RPI was treated using an air-abrasive device, Er,Cr:YSGG laser, and guided bone regeneration (GBR). Case Description. A 65-year-old Caucasian male presented with a draining fistula associated with an implant at tooth #3. Tooth #3 revealed periapical radiolucency two years before the implant placement. Tooth #3 was extracted, and a ridge preservation procedure was performed followed by implant rehabilitation. A periapical radiograph (PA) showed lack of bone density around the implant apex. The site was decontaminated with an air-abrasive device and Er,Cr:YSGG laser, and GBR was performed. The patient was seen every two weeks until suture removal, followed by monthly visits for 12 months. The periapical X-rays, from 6 to 13 months postoperatively, showed increased bone density around the implant apex, with no signs of residual clinical or radiographic pathology and probing depths ≤4 mm. Conclusions. The etiology of RPI in this case was the placement of an implant in a previously infected site. The use of an air-abrasive device, Er,Cr:YSGG, and GBR was utilized to treat this case of RPI. The site was monitored for 13 months, and increased radiographic bone density was noted.
Heart-lung transplantation

Heart-lung transplantation itself is not a particularly difficult operation technically. It is the setting in which this procedure is performed which is difficult. The three issues of importance in a successful outcome are appropriate harvest of the heart-lung bloc from the donor, careful explant of the heart and lungs of the recipient, and finally the implant of the heart-lung bloc into the recipient. None of this requires extraordinary technical skill, but does require careful coordination and planning as well as adhering to some fundamental principles. One of the major pitfalls encountered is bleeding related to the explant procedure. Another is graft failure related to harvest and/or the implant procedure. The third is injury to either the phrenic nerve(s) or the left recurrent laryngeal nerve related to the explant procedure. Heart-lung transplantation is a major investment in resources of all sorts including financial, personnel, as well as the organs themselves. It is absolutely imperative that this procedure be performed only by experienced surgeons in centers with established expertise.
PAROXYSMAL FLUTTER OF THE DIAPHRAGM: A REPORT OF FIVE CASES.

Abstract Five cases of diaphragmatic flutter are presented. In 2 patients the fluttering episodes were chronic and recurrent; the others had isolated or sporadic attacks. The paroxysms of diaphragmatic flutter were associated with great subjective distress in each patient, but serious clinical sequelae did not occur. In 1 patient with pre-existing obstructive emphysema, however, carbon dioxide retention was observed during fluttering. Possible psychosomatic factors in etiology were noted in each case. Flutter of the diaphragm was confirmed by fluoroscopy and/or electrocardiogram in all subjects. The rate and rhythm of fluttering, amplitude, and symmetry of diaphragmatic motion were highly variable. Comments are made on the physiologic measurements and electrocardiograms in the disturbance.
The Seely-Zyskind Results

We now take up the search for optimal unbiased estimates in certain quite general linear models, a search which historically led to one of the first truly general solutions to optimal estimation of variance components. This is accomplished through a careful presentation of results which were developed in a series of papers by Justus Seely and George Zyskind: Zyskind [1967], Seely [1971], and Seely and Zyskind [1971]. Then at the end of the chapter this material is applied to the original variance component problem.
ASYMPTOTIC STABILITY OF A CLASS OF STOCHASTIC INTERCONNECTED SYSTEMS

The stability of a class of stochastic interconnected systems is examined in the Lyapunov sense. Subsystem Lyapunov functions are used to construct Lyapunov functions for the composite system. The results presented are sufficient conditions for asymptotic stability with probability one.
Abstract B53: Intra-tracheal delivery of low-dose bacterial lipopolysaccharides protects against tumor formation in the KP lung adenocarcinoma model

While genetically engineered mouse models (GEMM) of lung adenocarcinoma (LUAD) recapitulate some aspects of the histopathology of human LUAD, they poorly reflect the inflammatory components of human LUAD. In this study, we performed repeated weekly intra-tracheal dosing with bacterial lipopolysaccharides (LPS) after adenoviral-Cre (AdCre) delivery into K-RasLSL-G12D/+; p53fl/fl mice to examine the effect of inflammation on lung adenocarcinoma progression. LPS has been historically used to study the acute inflammatory response both locally and systemically in animal models. The typical response involves recruitment and activation of innate immune cells, mainly neutrophils and macrophages, to the site of delivery and/or production of pro-inflammatory cytokines including TNF-alpha, IL-6 and IL-1. Repeated long-term conditioning with low-dose LPS results in alveolar wall thickening as observed by uCT and the accumulation of lymphoid aggregates in the lung. However, surprisingly, LPS conditioning drastically reduced tumor incidence from 75% in the control group to 25%. Furthermore, starting LPS delivery four weeks after AdCre instillation, to eliminate any possible LPS effects on adenoviral delivery and K-Ras induction/p53 loss, still resulted in drastically reduced lung tumor formation suggesting that the effect results from an LPS-induced immune response. Two LPS instillations were sufficient to elicit this effect. Short-term antibody-mediated depletion of neutrophils or CD8+ T cells also did not abrogate the effect of LPS on tumor formation. In vitro re-stimulation of CD8+T cells (from blood or spleen) from tumor-free animals with KP tumor cells did not elicit interferon-gamma production, as assayed by intra-cellular cytokine staining and ELISPOT, suggesting that a cell type other than CD8+ T-cells or neutrophils mediates the effect. Interestingly and consistent with the inhibitory effect of LPS on tumor formation, multiple pneumonia diagnoses in COPD patients/smokers has been associated with a lower odds ratio of developing lung cancer in humans. Identifying the cell-type (s) and mechanisms mediating the anti-tumor effect of LPS will help in defining the aspects of immune response that inhibit LUAD progression. Citation Format: Ganapathy Sriram, Lauren Milling, Darrell J. Irvine, Michael B. Yaffe. Intra-tracheal delivery of low-dose bacterial lipopolysaccharides protects against tumor formation in the KP lung adenocarcinoma model [abstract]. In: Proceedings of the AACR Special Conference on Tumor Immunology and Immunotherapy; 2017 Oct 1-4; Boston, MA. Philadelphia (PA): AACR; Cancer Immunol Res 2018;6(9 Suppl):Abstract nr B53.
Understanding Sources of Breakthrough Emergence

The present paper investigates where scientific breakthroughs arise from within a community and what characteristics make a particular scientist more likely to discover a breakthrough, defined as t...
CRT-700.10 The Impact of Gradient And Flow on the Outcomes of TAVR in Severe Aortic Stenosis with Preserved Left Ventricular Ejection Fraction

While transaortic flow and gradient are important determinant of prognosis in patients with severe AS treated medically or with surgical aortic valve replacement, it is unclear whether these echocardiographic values are still predictive of outcomes in patients with severe aortic stenosis with
Increased Water Intake Decreases UTI Recurrence in Women.

Drinking an additional 1.5 liters per day of water halved the recurrence of UTI in women with a history of at least three episodes per year.
Asymmetric Motivated Reasoning in Investor Judgment

Whereas prior research in accounting shows that both long and short investors’ incentivized directional preferences influence their information processing, we test whether long investors are more prone than short investors to forming biased beliefs. We predict that motivated reasoning is muted for short investors because the investing setting conveys a contextual preference—for prices to go up—that is directionally inconsistent with short investors’ incentivized preference. Experiment 1 tests for asymmetric motivated reasoning in an investing setting in which participants take either long or short positions. Results indicate that compared to a rational benchmark, long traders’ estimates of future stock price exhibit upward bias while short traders’ estimates are unbiased. Consistent with motivated reasoning as the process underlying these results, the magnitude of long traders’ bias becomes less pronounced as the amount of uncertainty in the information environment decreases. A second experiment provides additional evidence of our theory and tests for asymmetric motivated reasoning beyond the investing setting. Overall, our paper contributes new insights into differences between long and short investors and speaks to the broader literature on bias in judgment and decision-making that spans multiple fields.
Heavy-Atom-Free Red-to-Yellow Photon Upconversion in a Thiosquaraine Composite

We demonstrate a completely heavy-atom-free red-to-yellow triplet–triplet annihilation (TTA) photon upconversion system using a thionated squaraine sensitizer, both in fluid solution and in a solid...
A unification of finite deformation J2 Von-Mises plasticity and quantitative dislocation mechanics

Abstract We present a framework which unifies classical phenomenological J2 and crystal plasticity theories with quantitative dislocation mechanics. The theory allows the computation of stress fields of arbitrary dislocation distributions and, coupled with minimally modified classical (J2 and crystal plasticity) models for the plastic strain rate of statistical dislocations, results in a versatile model of finite deformation mesoscale plasticity. We demonstrate some capabilities of the framework by solving two outstanding challenge problems in mesoscale plasticity: 1) recover the experimentally observed power-law scaling of stress-strain behavior in constrained simple shear of thin metallic films inferred from micropillar experiments which all strain gradient plasticity models overestimate and fail to predict; 2) predict the finite deformation stress and energy density fields of a sequence of dislocation distributions representing a progressively dense dislocation wall in a finite body, as might arise in the process of polygonization when viewed macroscopically, with one consequence being the demonstration of the inapplicability of current mathematical results based on Γ-convergence for this physically relevant situation. Our calculations in this case expose a possible ‘phase transition’ - like behavior for further theoretical study. We also provide a quantitative solution to the fundamental question of the volume change induced by dislocations in a finite deformation theory, as well as show the massive non-uniqueness in the solution for the (inverse) deformation map of a body inherent in a model of finite strain dislocation mechanics, when approached as a problem in classical finite elasticity.
Topological crystalline phases in a disordered inversion-symmetric chain

When translational symmetry is broken by bulk disorder, the topological nature of states in topological crystalline systems may change depending on the type of disorder that is applied. In this work, we characterize the phases of a one-dimensional chain with inversion and chiral symmetries, where every disorder configuration is inversion symmetric. By using a basis-independent formulation for the inversion topological invariant, chiral winding number, and bulk polarization, we are able to construct phase diagrams for these quantities when disorder is present. We show that unlike the chiral winding number and bulk polarization, the inversion topological invariant can fluctuate when the bulk spectral gap closes at strong disorder. Using the position-space renormalization group, we are able to compare how the inversion topological invariant, chiral winding number, and bulk polarization behave at low energies in the strong disorder limit. We show that with inversion-symmetry-preserving disorder, the value of the inversion topological invariant is determined by the inversion eigenvalues of the states at the inversion centers, while quantities such as the chiral winding number and the bulk polarization still have contributions from every state throughout the chain. We also show that it is possible to alter the value of the inversion topological invariant in a clean system by occupying additional states at the inversion centers while keeping the bulk polarization fixed. We discuss the implications of our results for topological crystalline phases in higher-dimensional electronic systems, and discuss potential experimental realizations in ultracold-atomic systems.
Community planning, citizen action, and sustainability in a southern California edge city: San Diego’s University community, 2000–2018

This paper examines the role of community planning groups and engaged citizens in planning for sustainability in a southern California ‘edge city’. Through a case study of San Diego’s University Co...
The Development of Externalizing and Internalizing Behaviors Among Youth With or Without a Family History of Substance Use Disorder: The Indirect Effects of Early-Life Stress and Impulsivity

Youth with a family history of substance use disorder (FH+) are more prone to have externalizing and internalizing problems compared to youth without a family history of substance use disorder (FH−), increasing the likelihood of later maladjustment. However, mechanisms for this association remain understudied. In this longitudinal study, we examined if FH+ youth are more likely to experience early-life stressors (ELS), which in turn would increase impulsivity and the expression of externalizing and internalizing behaviors. Data were collected from youth and a parent (n = 386) during a baseline assessment (age 10–12 years) and every six months when the youth was 13–16 years old. In support of the primary hypothesis, FH+ youth reported higher levels of externalizing and internalizing behaviors through ELS to impulsivity providing a developmental pathway through which FH+ youth are more prone to externalizing and internalizing problems.
Dabigatran reversal with idarucizumab prior to lung transplantation.

Background When the transplant candidates are receiving oral anticoagulation therapy before transplantation, it is crucial to have an urgent reversal strategy to prevent hemorrhagic complications perioperatively. The aim of this study was to present the experience with idarucizumab to reverse the anticoagulant activity of dabigatran prior to lung transplantation. Methods A single-center retrospective study was performed to analyze the clinical outcomes of idarucizumab use before lung transplantation. Results Between July 2016 and June 2019, six patients were on dabigatran at the time of transplantation. Out of the six patients, four patients received idarucizumab. These four recipients received a median of 3 units (range 0-4 units) of packed red blood cells (pRBCs) and 450 ml (range 250-1500 ml) of intraoperative salvage of shed blood (cell saver blood) during the lung transplant. The two patients who were not administered idarucizumab received 5 units and 13 units of pRBCs and 900 ml and 3600 ml of cell saver blood, respectively. There was no grade 3 primary graft dysfunction (PGD) at 72 hours after transplantation or in-hospital mortality in idarucizumab group. In the group without idarucizumab, there was one case of grade 3 PGD without any in-hospital mortality. Conclusion Dabigatran reversal with idarucizumab provides reasonable hemostasis during lung transplantation.
Semimetallicity and electron-hole liquid in two-dimensional C and BN based compounds

An insulating-metallic transition mediated by substitutional atoms is predicted in a series of two-dimensional carbon-based structures. Introducing Si atoms in selected sites of tetrahexcarbon [B. Ram and H. Mizuseki, Carbon 137, 266 (2018)] according to rational chemical rules, metallicity by trivial band inversion without a band gap opening is induced. Additional substitution of the remaining C atoms by BN dimers introduces no changes in the metallic properties. A series of isomorphous two-dimensional materials with isoelectronic structures derived by exchanging group IV elements exhibiting various band gaps is obtained. Dynamical stability is verified with a phonon analysis and beyond the harmonic approximation with molecular dynamics up to room temperature. The semimetallic compounds have well-nested pockets of carriers and are good candidates for the formation of an excitonic insulator.
Glinda: Supporting Data Science with Live Programming, GUIs and a Domain-specific Language

Researchers have explored several avenues to mitigate data scientists’ frustrations with computational notebooks, including: (1) live programming, to keep notebook results consistent and up to date; (2) supplementing scripting with graphical user interfaces (GUIs), to improve ease of use; and (3) providing domain-specific languages (DSLs), to raise a script’s level of abstraction. This paper introduces Glinda, which combines these three approaches by providing a live programming experience, with interactive results, for a domain-specific language for data science. The language’s compiler uses an open-ended set of “recipes” to execute steps in the user’s data science workflow. Each recipe is intended to combine the expressiveness of a written notation with the ease-of-use of a GUI. Live programming provides immediate feedback to a user’s input, whether in the form of program edits or GUI gestures. In a qualitative evaluation with 12 professional data scientists, participants highly rated the live programming and interactive results. They found the language productive and sufficiently expressive and suggested opportunities to extend it.
NRCT Clinical Study in to Identify Acetaminophen-Induced Liver Injury Mechanism

Acetaminophen (APAP) (N-acetyl-p-aminophenol) is a chemical molecule used to relieve pain and lower fever in paracetamol medications. The Food and Drug Administration (FDA) advisory group warned in June 2009 about the risk of APAP overdose due to its side effects, which include drug-induced liver disease. In addition, the FDA has begun multicenter non-interventional case-control studies to collect data on APAP toxicity biomarkers in children and adolescents. The National Center for Toxicological Research (NCTR), which is part of the FDA, coordinates the execution of APAP clinical trials in collaboration with other health institutes (hospitals, universities, and clinical centres) around the United States. The goal of these clinical trials is to gather enough data to create a list of biomarkers connected to acetaminophen toxicity that can be matched with specific adduct proteins; this information can then be used to examine and predict future hazards in children who are taking acetaminophen.
Abnormal levels of mitochondrial proteins in plasma neuronal extracellular vesicles in major depressive disorder.

To characterize neuronal mitochondrial abnormalities in major depressive disorder (MDD), functional mitochondrial proteins (MPs) extracted from enriched plasma neuron-derived extracellular vesicles (NDEVs) of MDD participants (n = 20) were quantified before and after eight weeks of treatment with a selective serotonin reuptake inhibitor (SSRI). Pretreatment baseline NDEV levels of the transcriptional type 2 nuclear respiratory factor (NRF2) which controls mitochondrial biogenesis and many anti-oxidant gene responses, regulators of diverse neuronal mitochondrial functions cyclophilin D (CYPD) and mitofusin-2 (MFN2), leucine zipper EF-hand containing transmembrane 1 protein (LETM1) component of a calcium channel/calcium channel enhancer, mitochondrial tethering proteins syntaphilin (SNPH) and myosin VI (MY06), inner membrane electron transport complexes I (subunit 6) and III (subunit 10), the penultimate enzyme of nicotinamide adenine dinucleotide (NAD) generation nicotinamide mononucleotide adenylytransferase 2 (NMNAT2), and neuronal mitochondrial metabolic regulatory and protective factors humanin and mitochondrial open-reading frame of the 12S rRNA-c (MOTS-c) all were significantly lower than those of NDEVs from matched controls (n = 10), whereas those of pro-neurodegenerative NADase Sterile Alpha and TIR motif-containing protein 1 (SARM1) were higher. The baseline NDEV levels of transcription factor A mitochondrial (TFAM) and the transcriptional master-regulator of mitochondrial biogenesis PPAR γ coactivator-1α (PGC-1α) showed no differences between MDD participants and controls. Several of these potential biomarker proteins showed substantially different changes in untreated MDD than those we reported in untreated first-episode psychosis. NDEV levels of MPs of all functional classes, except complex I-6, NRF2 and PGC-1α were normalized in MDD participants who responded to SSRI therapy (n = 10) but not in those who failed to respond (n = 10) by psychiatric evaluation. If larger studies validate NDEV MP abnormalities, they may become useful biomarkers and identify new drug targets.
Elevated fecal calprotectin is linked to psychosocial complexity in pediatric functional abdominal pain disorders.

OBJECTIVE Children with functional abdominal pain disorders (FAPD) and clinical elevations in three risk areas (anxiety, functional disability, and pain) have been found to be at increased risk for persistent disability. We evaluated if the presence of these three risk factors corresponded with greater gastrointestinal inflammation (measured via fecal calprotectin; FC) compared to those with no risk factors. FC concentration differences between children with three risk factors and those with one and two risk factors were explored. RESULTS Fifty-six children with FAPD (Mage = 12.23) completed measures of anxiety (Screen for Child Anxiety Related Disorders), disability (Functional Disability Inventory), and pain intensity (Numeric Rating Scale). Participants were stratified into risk groups (range: 0-3). Fisher's exact tests were conducted to determine if children with three versus fewer risk factors were more likely to have elevated FC (≥ 50 µg/g) versus normal levels. Children with three risk factors (MFC = 86.04) were more likely to have elevated FC compared to children with zero (MFC = 25.78), one (MFC = 38.59), and two risk factors (MFC = 45.06; p's < 0.05). Those with three risk factors had borderline elevated FC concentrations whereas those with fewer had normal FC concentrations. Findings suggest the importance of a biopsychosocial approach to help elucidate a FAPD phenotype.
Post-Mastectomy Acute Skin Toxicity Assessment Between Particle and Photon Therapy.

Purpose/Objective(s) To compare acute skin toxicity following post-mastectomy photon (XRT) and skin-sparing proton radiotherapy (PRT). Materials/Methods 179 consecutive women with unilateral, non-inflammatory breast cancer were treated with conventionally fractionated post-mastectomy radiotherapy (PMRT) between 2015 and 2019. Prescription was 50 Gy (RBE) in 25 fractions to the chest wall and regional lymph nodes. PRT was administered with a median of two multi-field optimized fields (intensity modulated proton therapy). The chest wall skin was defined as the first 3 mm from the external body surface. XRT and PRT planning objectives with respect to skin were to achieve microscopic disease target coverage while limiting surface hot spots. For XRT 3-5 mm daily bolus was most commonly employed to achieve these objectives. PRT planning objectives were V90% > 90% and D1cc Results Treatment was PRT in 96 and XRT in 83 (95% 3D conformal radiotherapy with a wide tangent technique, 5% intensity modulated radiotherapy). There was no significant difference between the two groups with respect to age, stage, receipt of chemotherapy, immediate breast reconstruction, diabetes mellitus, body mass index (BMI), or current or former smoking history. 65% PRT and 61% XRT pts had immediate breast reconstruction. Median follow-up was 25 months. There was no significant difference in grade ≥2 or grade 3 dermatitis between PRT and XRT at 47% vs 48%, P = 0.86 and 3% vs 7%, P = 0.22, respectively. There was a trend for higher grade ≥2 dermatitis in current or former smokers vs never smokers (60% vs 43%, P = 0.06). BMI (P = 0.11), diabetes (P = 0.41), and breast reconstruction (P = 0.63) were also not associated with grade ≥2 dermatitis. Dosimetric parameters including the skin dose to 1 cc (P Conclusion Post-mastectomy PRT administered with our skin-sparing technique is not associated with higher rates of acute dermatitis than XRT.
Microchemical urinalysis. IX - Determination of hydroxyproline in urine.

A simplified procedure is described for the determination of hydroxyproline in human or monkey urine. In this procedure 1 ml of urine is subjected in succession to hydrolysis, oxidation, extraction, and color development. During these steps impurities and interfering substances are eliminated, thus resulting in a chromophore due to hydroxyproline alone.
Interband Scattering Contributions to the Resistivity of A-15 Metals

We calculate the temperature dependence of the resistivity of Nb3Sn and V3Si below 50 K in the interband-scattering model using realistic phonon densities of states and find agreement with experiment. For V3Si we also find that phonon-mode shifting is in part responsible for, though not the dominant cause of, the observed negative deviation from linearity of the high-temperature resistivity. We present calculations to suggest that this negative deviation from linearity of the high-temperature resistivity is predominantly due to sharp structure in the electronic density of states N(є) near the Fermi energy єF. We further argue that the unusually large magnitude of the high-temperature resistivity of Nb3Sb, a low-Tc (~ 0.2 K), low density-of-states A-15 superconductor, is due to thermally-accessible structure in N(є) within a characteristic phonon energy from єF.
Location of unique sequences in tobacco mosaic virus ribonucleic acid.

Abstract Tobacco mosaic virus has been partially stripped of its protein coat by sodium dodecyl sulfate. The nucleic acid exposed was digested with T1 ribonuclease and the products were examined for the presence of three oligonucleotides of unique sequence. The results indicate the location of two of the unique oligomers to be near the 5'-OH-linked end and the third to be near the middle of tobacco mosaic virus RNA. They also provide evidence that the cistron for tobacco mosaic virus coat protein is not situated at the 5'-OH-linked terminus.
Abstract W P214: Identifying Stroke Symptoms in the Field: What are we Missing?

Introduction: Emergency Departments (ED) are increasingly activating stroke codes based on assessment of stroke symptoms via Emergency Medical Services (EMS). Accurate assessment of stroke symptoms by EMS facilitates rapid assessment in the ED, leading to prompt diagnosis and treatment during an acute stroke. Delays in treatment can occur when stroke symptoms are not recognized in the field. Hypothesis: We hypothesized that trends existed in stroke symptoms most commonly missed by EMS. Methods: A retrospective cohort study of 170 records was reviewed, for all patients receiving acute stroke care at an urban hospital from October 2013 to May 2014. Inclusion criteria: stroke code activation by EMS or in the ED, and patient arrival by EMS. Exclusion criteria: stroke code activations after admission to the hospital, and patients arriving via private transportation. Results: 112 patients met the inclusion and exclusion criteria. 90 patients (80%) had stroke codes were initiated by EMS. The remaining 22 patients had stroke codes initiated by the ED MD after arrival. The records of the 22 patients arriving to the ED without advanced EMS notification were reviewed. Aphasia was documented in the EMS record for 8 patients (36%). An additional 8 patients (36%) with documented stroke symptoms arrived without EMS notification due to improving symptoms or unclear last known well time. Five of the 22 patients (23%) arriving without EMS pre-notification had had aaphasia documented as an initial finding by ED MD, had a stroke code activation and received IV tPA. One of the 5 patients (13%) also had improving symptoms documented by EMS. Conclusion: An opportunity exists for improved recognition of aphasia as a stroke symptom by EMS, including both expressive and receptive components. Likewise, further education is needed correlating aphasia with the likelihood of IV tPA initiation in the ED. This study also highlights the importance of recognizing the waxing and waning nature of stroke symptoms. Rapidly improving symptoms should not preclude stroke code initiation via EMS, as some of these patients are still IV tPA candidates.
A fine-wire electromyographic investigation of the gluteus minimus and gluteus medius muscles.

Abstract The purpose of this study was to investigate the functions of the gluteus minimus and gluteus medius muscles through the use of fine-wire electromyography. Electrical activity of the gluteus minimus and gluteus medius muscles of 13 subjects, six females and seven males, was recorded during a series of basic anatomical movements. Results showed that the gluteus minimus functioned as an abductor, medical rotator, extensor, and in some cases a flexor of the thigh. The gluteus medius functioned as an abductor, extensor, and medical rotator in six of the 13 subjects. It also exhibited some activity during flexion in five of the subjects tested.
Ways to Improve Efficiency of Pesticide and Energy Consumption of Roses under Glass

In cooperation with growers and the research stations in Naaldwijk and Aalsmeer, LEI-DLO has searched for “closed production systems” as a way to environmentally friendly farming. An important part of this research is registration of the consumption of water, fertilizers and pesticides on specialized glassholdings.
Prediction Model for Eating Property of Indica Rice

One hundred and five indica rice samples were analyzed by determining head rice yield, chalkiness, protein content, gel consistency and amylose content. Taste scores of rice were obtained by sensory evaluation. Support vector machine (SVM) and K-nearest neighbors (KNN) models were established with physicochemical properties as attributes. In each linear correlation, amylose content had highest coefficient with taste score, but in the mutual influence, gel consistency showed highest correlation. In SVM model, the accuracy of the training set and testing set were 99.0% and 93.3%, respectively; in KNN model, they were 74.3% and 73.3%, respectively. These results showed that the nonlinear relationship between eating property and physicochemical properties of indica rice was found. It was concluded that SVM, which extracts nonlinear features, can be used to effectively predict the taste class of unknown. Practical Applications Support vector machine (SVM) is an effective prediction model used to represent the eating property of indica rice. The model showed that the nonlinear relationship between eating property and physicochemical properties of indica rice. The results of the present study can also serve as a valuable resource to further explore the utilization of the prediction model in sensory evaluation of rice, and expound the relationship between eating property and other properties of rice.
Bleeding Risks in Interventional Radiology

Bleeding complications are a concern for patients who have interventional radiology procedures. This article discusses reasons for abnormal coagulation, conditions that increase patients' risk for bleeding from interventional procedures, coagulation parameters and common methods to modify the hemostatic system.
Microbead Arrays for the Analysis of ErbB Receptor Tyrosine Kinase Activation and Dimerization in Breast Cancer Cells

Receptor tyrosine kinases (RTKs) in the ErbB family (EGFR, ErbB2, ErbB3, and ErbB4) are implicated in a variety of human malignancies. Accordingly, determination of both expression and activation (dimerization/heterodimerization and phosphorylation) of ErbB proteins is critical in defining their functional role in cancer. Efficient and comprehensive methods to study molecular functions of ErbB family of RTKs are needed not only for improvements in diagnostics but also for early screening of targeted drugs (eg, small molecule inhibitors and therapeutic antibodies). We report development of 3 multiplex microbead immunoassays for simultaneous detection of expression, protein–protein interactions, and phosphorylation of these RTKs. These novel multiplex immunoassays were used to study ErbB RTKs under different cell activation conditions in 2 breast cancer cell lines (MDA-MB-453 and MDA-MB-468) and an epidermoid cancer cell line (A431). The results were confirmed by immunoprecipitation/western blot. Importantly, the multiplex immunoassay facilitated time-course studies in these cell lines after cell activation with EGF and neuregulin, revealing the kinetics of phosphorylation of the ErbB family RTKs. This study demonstrates the utility of the Luminex® multiplex system as an efficient and comprehensive approach to study different aspects of molecular roles of these RTKs. Importantly, the study provides proof-of-concept for the utility of the multiplex microbead immunoassay approach for potential use in efficient, robust, and rapid screening of drugs, particularly those targeting functional aspects of these potent signaling molecules. In addition, the assays described here may be useful for cancer diagnostics and monitoring efficacy of therapy targeting the ErbB family of RTKs.
Networked Operations of Hybrid Radio Optical Communications Satellites

In order to address the increasing communications needs of modern equipment in space, and to address the increasing number of objects in space, NASA is demonstrating the potential capability of optical communications for both deep space and near-Earth applications. The Integrated Radio Optical Communications (iROC) is a hybrid communications system that capitalizes on the best of both the optical and RF domains while using each technology to compensate for the other's shortcomings. Specifically, the data rates of the optical links can be higher than their RF counterparts, whereas the RF links have greater link availability. The focus of this paper is twofold: to consider the operations of one or more iROC nodes from a networking point of view, and to suggest specific areas of research to further the field. We consider the utility of Disruption Tolerant Networking (DTN) and the Virtual Mission Operation Center (VMOC) model.
The diffusion of core publications in american sociology

Citations to articles published during 1960 in three “core” sociological journals, cited in ten sociological journals (1961-70), are examined. One-third of the articles were not cited at all, while only eleven percent of the cited articles were cited in more than one-half (six or more) of the journals. Articles are more likely to be cited in core journals than in specialized journals. Studies of the reading and citing practices of authors are needed. Finally, it is suggested that the core journals may not play an integrating role within sociology and that greater attention should be focused on the specialty journals.
Elastic moduli, density, and structural relaxation in bulk amorphous Zr41.2Ti13.8Cu12.5Ni10Be22.5 alloy

Abstract The thermal expansion and elastic properties of bulk amorphous Zr 41.2 Ti 13.8 Cu 12.5 Ni 10 Be 22.5 alloy are reported. The thermal expansion was measured between 80 K and 773 K, which includes the glass transition and crystallization temperatures. The elastic moduli were measured at room temperature using a novel resonant ultrasonic spectroscopy technique in samples annealed at increasing temperatures between 300 K to 773 K. The thermal expansion data were used to deduce the Debye temperature Θ D , and the Gruneisen parameter, γ. The changes in elastic properties are discussed in terms of the annihilation and redistribution of free volume in the bulk amorphous state.
Conditional expectations on von Neumann algebras: A new approach

Abstract In the framework of non-commutative probability theory on von Neumann algebras the concept of conditional expectation is redefined in such a way that it exists relative to arbitrary a priori distributions and subalgebras. We derive explicit expressions for the expectations relative to Abelian subalgebras and establish their connection with the concept of coarse-graining.
Radiative capture of fast neutrons by 40Ca

Abstract The radiative capture cross section for the reaction 40 Ca(n, γ) 41 Ca has been measured for the neutron energy range of 6.8–18.2 MeV. A NaI(Tl) anti-Compton spectrometer, a pulsed neutron beam, and time-of-flight techniques were utilized. The γ-ray spectra show strong transitions to the 1 f 7 2 ground state and a relatively high intensity of unresolved γ-rays to a group of levels at about 2 MeV, where two 3 2 − states are known to carry the 2 p 3 2 strength, and to levels around 4 MeV, which is the centroid energy of the 2 p 1 2 strength. Absolute cross sections were determined for these γ-ray transitions as well as the integrated cross section for transitions to bound states of 41 Ca. Only the cross section for the transition to the f 7 2 ground state of 41 Ca shows the resonance behavior predicted by the semidirect (collective) capture theory, but the agreement between the theoretical and measured f 7 2 cross sections is not satisfactory. The measured cross sections for the other γ-ray peaks are almost constant with neutron energy below about 15 MeV, in sharp contrast to the cross sections predicted by the semidirect theory for p 3 2 and p 1 2 transitions.
Photodegradation of two dinitrophenolic pesticide chemicals, dinobuton and dinoseb, applied to bean leaves.

Dinitrophenols and their esters are used as insecticides, acaricides, ovicides, herbicides, and fungicides. Residues of these pesticide chemicals are generally determined as the parent phenol, after saponification when necessary, by methods which normally do not detect many related compounds, such as those that might form by biological or photochemical oxidation or reduction. Since the photochemistry of dinitrophenolic pesticide chemicals is poorly understood, it is important to develop the information needed to interpret the data obtained in studies on the persistence and toxicology of residues on or in food and feed. Accordingly, cl4-1abeled preparations of 2-see-butyl-W,6-dinitrophenol (dino~eb, DNBP~and its isopropyl carbonate (dinobuton, AcreX~, Dessin~ were exposed to sunlight on growing bean foliage in order to determine the nature of the persisting residues.
Structural, antigenic and evolutionary analyses of immunoglobulins and T cell receptors.

We have had the pleasure of collaborating with Allen Edmundson for the past 15 years on the structure, binding properties and evolution of immunoglobulins and T cell receptors. Among the most significant contributions of our joint efforts were: (1) the predictive use of structural features of immunoglobulin domains to model the three-dimensional structures of the immunoglobulin domains of human T-cell receptor α and β chains as well as shark light chains and VH domains; (2) the finding that normal humans and other vertebrates express autoantibodies against combining site epitopes of their own T cell receptors; (3) the mapping of the peptide autoepitopes recognized in health, autoimmunity and retroviral infection; and (4) the determination that epitope recognition promiscuity is a characteristic property of the combining sites of IgM immunoglobulins ranging from those of sharks to those of humans. We briefly review the salient findings and status of these studies and indicate the future directions that we will pursue in their continuation. Copyright © 2002 John Wiley & Sons, Ltd.
Sulfate sources and oxidation chemistry over the past 230 years from sulfur and oxygen isotopes of sulfate in a West Antarctic ice core

[1] The sulfur and oxygen isotopic composition of sulfate in polar ice cores provides information about atmospheric sulfate sources and formation pathways, which have been impacted regionally by human activity over the past several centuries. We present decadal scale mean ice core measurements of Δ17O, δ34S, Δ33S, and Δ36S of sulfate over the past 230 years from the West Antarctic Ice Sheet (WAIS) Divide deep ice core drill site (WDC05-A). The low mean δ34S of non–sea-salt sulfate at WAIS Divide (6.0 ± 0.2‰) relative to East Antarctic coastal and plateau sites may reflect a combination of stronger influence of volcanogenic and/or stratospheric sulfate with low δ34S and the influence of frost flowers on the sea-salt sulfate-to-sodium ratio. Δ33S and Δ36S measurements are all within analytical uncertainty of zero but do not contradict a contribution of stratospheric sources to background sulfate deposition at WAIS Divide. Δ17O of non–sea-salt sulfate shows a small but significant increase between the late 1700s (1.8‰ ± 0.2‰) and late 1800s (2.6‰ ± 0.2‰), but the influence of stratospheric scale volcanic events on Δ17O in the early 1800s remains uncertain. An isotope mass balance model shows that the lack of change in Δ17O of non–sea-salt sulfate from the mid-1800s to early 2000s (2.4‰–2.6‰ ± 0.2‰) is consistent with previous atmospheric chemistry model estimates indicating preindustrial to industrial increases in O3 as high as 50% and decreases in OH of 20% in the southern polar troposphere, as long as H2O2 concentrations also increase by over 50%.
Computationally efficient method to compare the shape of planar Gaussian mixtures from point samples

We discuss the problem of recognizing the shape of planar objects consisting of "blobs" that can be modeled as Gaussian mixture densities. We describe an empirical comparison method, assuming a large number of independent samples are given for each distribution. Instead of comparing the Gaussian mixtures directly, we compare the underlying distribution of distances of each mixture. Since distances are invariant under rotations and translations, this provides a workaround to the problem of aligning the objects before comparing them-thus speeding the comparison process. We prove that the distribution of distances is a lossless representation of the shape of generic Gaussian mixtures. Our numerical experiments indicate that, when all the components of the Gaussian mixtures are equally weighted and have the same standard deviation matrix, the proposed method is no less accurate than methods that compare the planar mixtures directly. The extension of our method to the problem of recognizing halftone patterns is briefly discussed.
Contrasting perceptions of the risks of using nuclear energy sources in space

Abstract An open-ended interview procedure was used to elicit beliefs regarding the risks created by the use of nuclear energy sources in space. Respondents selected from two organizations of peace and environmental activists and from several engineering associations were found to have generally similar levels of knowledge, despite having very different attitudes toward the technology. A third group, drawn from the general public, performed more poorly in most respects. The details of each group's beliefs provide clues regarding the factors shaping their attitudes and the ways to formulate effective risk communications.
Comparison of score metrics for Bayesian network learning

In order to induct a Bayesian network from data, researchers proposed a variety of score metrics based on different assumptions. The score metric that performs best is of interest. In this paper, we compared the performance of five score metrics: uniform prior score metric (UPSM), conditional uniform prior score metric (CUPSM), Dirichlet prior score metric (DPSM), likelihood-equivalence Bayesian Dirichlet score metric (BDe), and minimum description length (MDL); resulting from five different assumptions: uniform prior, conditional uniform prior, Dirichlet prior, likelihood equivalence, and MDL. We used a three-node net, a five-node net, and the ALARM net to conduct several comparison experiments. The experimental results show that when they are applied to identify the true network structures, the DPSM yields the best discrimination score and BDe may fail to identify the true network if the equivalent sample size is not set properly. When they are applied to learn a network from data using the K2-like greedy search and the maximum likelihood (ML) parameter estimation, the network inducted by the K2D10, corresponding to the tenth-order DPSM, is most similar to the true network based on the cross-entropy criterion. It is concluded that the tenth-order DPSM is the best score metric and the corresponding K2D10 is the most reliable network learning algorithm.