cssi/SciSciGPT-SciSciNet huggingface dataset:
Anti-hyperlipidemic and insulin sensitizing activities of fenofibrate reduces aortic lipid deposition in hyperlipidemic Golden Syrian hamster

Cholesterol ester transfer protein (CETP) and apolipoprotein (apo) E are important in peroxisome proliferation activated receptor-α (PPAR-α)-mediated regulation of lipoprotein metabolism. Therefore, popularly used apolipoprotein E knockout mice are not suitable to evaluate PPAR-α agonists. In this study, we aimed to: a) evaluate hamster as a model for insulin resistance, hyperlipidemia and atherosclerosis; and b) investigate the effect of a PPAR-α activator, fenofibrate, in this model. A high fat high cholesterol (HFHC) diet increased serum cholesterol and triglycerides, but inclusion of fenofibrate in the diet decreased cholesterol and proatherogenic lipoproteins, VLDL and LDL, in a time-dependent manner. Concomitantly, serum levels of triglycerides also decreased. These reductions were attributed, in part, to the down-regulation of lipogenic genes and upregulation of lipoprotein lipase. The HFHC diet caused body weight gain and mild insulin resistance, both of which were prevented following the treatments with fenofibrate. Insulin resistance was further investigated in high fructose-fed hamsters. Fenofibrate prevented both hyperinsulinemia and hypertriglyceridemia. The insulin sensitizing activity of fenofibrate appeared to occur via reductions in protein tyrosine phophatase-1B. To determine whether lowering of lipids by fenofibrate treatment contributed to the reduced risks of developing atherosclerosis in hyperlipidemic hamsters, we measured lipid deposition in the aorta. Our results showed that fenofibrate treatment reduced aortic lipid deposition by 70%. These findings suggest that hamster may be an adequate animal model to evaluate the efficacy of lipid lowering, insulin sensitizing and antiatherosclerotic agents. We also show that fenofibrate is an effective antiatherosclerotic agent in hyperlipidemic hamster model.
Project Using iPads for Clinical Supervision

The University of West Georgia Speech and Hearing Clinic is a part of the Comprehensive Community Clinic (CCC) located in the College of Education. Each semester, 2025 graduate students complete a...
FINANCIAL VALUE OF REPUTATION: EVIDENCE FROM THE eBAY AUCTIONS OF GMAIL INVITATIONS*

In this article, I utilize a unique collection of auctions on eBay to study the influence of seller reputation on auction outcomes. In a market of homogeneous goods with non-enforceable contracts, I find that sellers who improve their reputation by one quintile from the lowest, experience a 6.2% higher probability of sale and a 6.1% hike in valuation after adjusting for truncation bias from failed auctions and explicitly controlling for unobservable seller heterogeneity. This study also shows that in addition to a dimension of reputation universal across different product markets, the product-specific dimension of reputation significantly affects the auction outcomes.
William James on Sensation and Perception

Beginning with an analysis of a famous quotation from James’ Principles, this essay details some of the highlights of James’ treatment of sensation and perception. The primary source is a chapter on discrimination and comparison, in which emphasis is placed on the way people react to difference and sameness, reactions that may be fundamental to the psychophysical methods developed by Fechner and to later techniques, such as stimulus scaling and signal detection procedures, as well as to recent methods (preferential looking and habituation-dishabituation) for investigating perception in human infants. One can see considerable continuity between many of the issues raised in the Principles and those that have been addressed by perceptionists over the ensuing century, but James seems not to have had the direct impact in this domain that he has had, for example, on current conceptions of emotional processes. His associationist and functionalist positions may find contemporary expression in the seemingly dispar...
The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance

Birt-Hogg-Dube syndrome (BHD) is a rare, inherited genodermatosis characterized by hair follicle hamartomas, kidney tumors and spontaneous pneumothorax. The BHD locus was mapped to chromosome 17p11.2 by linkage analysis, and germline mutations in a novel gene (BHD) were identified in a panel of BHD families. Using RNA interference to decrease expression of the Drosophila BHD homolog (DBHD), we have demonstrated that DBHD is required for male germline stem cell (GSC) maintenance in the fly testis. Reduction of DBHD gene activity suppresses the GSC overproliferation phenotype associated with overexpression of either unpaired (upd) or decapentaplegic (dpp). Further genetic interaction experiments suggest that DBHD regulates GSC maintenance downstream or in parallel of the JAK/STAT and Dpp signal-transduction pathways. These findings suggest that the BHD protein may regulate tumorigenesis through modulating stem cells in human.
Broadband wireless sensing of radioactive chemicals utilizing inherent RF transmissions from pulse discharges

This paper reports a wireless sensing scheme that exploits gas discharges in microstructures and discharge-based sensors such as micromachined Geiger counters. Experiments are conducted on devices that have a glass-Si-glass stack of 8 times 8 mm2 footprint, with discharge gaps in the range of 300-550 mum. Electrical discharges triggered by exceeding the breakdown voltage and by ionization due to beta particles provide an RF spectrum spanning a bandwidth greater than 1.2 GHz, which extends into the ultra-wideband (UWB) range of communication. These are broadband signals that can be detected by AM and FM radios at distances greater than 50 cm from the sensor. Measurements of electric field strength and audio recordings from radio receivers are reported
Reading 95 Theses on Politics, Culture, and Method

What has the discipline that calls itself “political science” to do with literary studies, anthropology, the philosophy of language, structural linguistics, or hermeneutics? With postcolonial theory, poststructuralism, semiotics, psychoanalysis, feminist theory, cultural studies, and other such pursuits? Anne Norton's 95 Theses raises these questions at the nexus of “Politics, Culture, and Method.” Asked to consider this work both generally and with an eye to its potential impact on the discipline of political science, the subfield of political theory and disciplinary or subfield divisions, I find myself caught between the terms of the invitation and the implosion of those terms for which the Theses offer no small spark. Curiously though, its most incendiary aspects appear not in Norton's own measured prose, but rather on its dust jacket. The back cover, for example, dubs it “an attack on the social science establishment,” while an inner flap applauds Norton as a “political scientist” who has launched “a polemic against the orthodoxy of her own field.” There, too, strident phrasing names the polemical target: “the antiquated and stultifying models in the textbooks on method, in courses on methodology, championed by the self-appointed gatekeepers of a narrow and parochial political science.” Norton, we're told, “opens the gates to more new practices, new principles, new questions, more methods, and more demanding ethical and scientific criteria.” Kirstie M. McClure is Associate Professor of Political Science and English at University of California, Los Angeles (kmmac@ucla.edu).
New drug treatments for diarrhoea

This paper reviews the scientific background to the development of new drugs for the treatment of diarrhoeal diseases, and it includes an update of three classes of drugs which may prove useful; gut specific alpha2-adrenergic agonists, intestinal Cl- channel blockers, and somatostatin analogues.
Emplacement and Thermal History of a Rhyolite Lava Flow near Fortymile Canyon, Southern Nevada

The rhyolite of Comb Peak is one of a series of related rhyolitic lava flows and domes that postdate formation of the Timber Mountain caldera in southern Nevada. The Comb Peak body consists of bedded rhyolitic tuffs overlain by a rhyolitic lava flow that has a foliated interior with fluidal struc- ture, enveloped by breccia. The vent for the lava flow and the pre-eruption topography have been exposed by erosion and indicate the general condi- tions and direction of flow. These indications have been corroborated by study of the foliation pattern and by a semiquantitative statistical analysis of flow folds and related features. Geologic relationships in- dicate that brecciation of the lava flow occurred mainly during periods when the flow was spreading, whereas the body eroded its floor and walls much as does a glacier during periods when the flow was con- fined. Tuffs adjacent to parts of the lava flow have been conspicuously modified. Local compaction and in- duration ("fusion") by the hot lava caused the bed- ded tuffs to weld so that they resemble welded ash- flow tuffs except for characteristic bedding and sorting indicative of their ash-fall origin. The zone of "fusion" is everywhere parallel to the contacts of the lava flow and intersects bedding at high angles. Locally "fusion" affected the tuffs for a thickness of 75 m or more from the contact of the flow. Approxi- mate calculation of the heat flow necessary to ac- complish the observed alteration indicates that sim- ple conduction from the margins of the flow would not have been adequate. Heat transfer was greatly increased, probably by convection of superheated steam from the edges of the flow through porous tuffs. Simultaneous cooling and crystallization of the "fused" tuffs and the lava flow produced a series of zones that encompass the entire Comb Peak body and cross contacts between emplacement units. The basal vitrophyre zone, for example, is in the lowest part of the lava flow in many places, but elsewhere it is entirely within "fused" tuffs and has been mapped as much as 300 m beyond the present posi- tion of the flow contact.
Mucosal Adjuvant Properties of Mutant LT-IIa and LT-IIb Enterotoxins That Exhibit Altered Ganglioside-Binding Activities

LT-IIa and LT-IIb, the type II heat-labile enterotoxins of Escherichia coli, are closely related in structure and function to cholera toxin and LT-I, the type I heat-labile enterotoxins of Vibrio cholerae and E. coli, respectively. Recent studies from our group demonstrated that LT-IIa and LT-IIb are potent systemic and mucosal adjuvants. To determine whether binding of LT-IIa and LT-IIb to their specific ganglioside receptors is essential for adjuvant activity, LT-IIa and LT-IIb enterotoxins were compared with their respective single-point substitution mutants which have no detectable binding activity for their major ganglioside receptors [e.g., LT-IIa(T34I) and LT-IIb(T13I)]. Both mutant enterotoxins exhibited an extremely low capacity for intoxicating mouse Y1 adrenal cells and for inducing production of cyclic AMP in a macrophage cell line. BALB/c female mice were immunized by the intranasal route with the surface adhesin protein AgI/II of Streptococcus mutans alone or in combination with LT-IIa, LT-IIa(T34I), LT-IIb, or LT-IIb(T13I). Both LT-IIa and LT-IIb potentiated strong mucosal and systemic immune responses against AgI/II. Of the two mutant enterotoxins, only LT-IIb(T13I) had the capacity to strongly potentiate mucosal anti-AgI/II and systemic anti-AgI/II antibody responses. Upon boosting with AgI/II, however, both LT-IIa(T34I) and LT-IIb(T13I) enhanced humoral memory responses to AgI/II. Flow cytometry demonstrated that LT-IIa(T34I) had no affinity for cervical lymph node lymphocytes. In contrast, LT-IIb(T13I) retained binding activity for T cells, B cells, and macrophages, indicating that this immunostimulatory mutant enterotoxin interacts with one or more unknown lymphoid cell receptors.
Linear-quadratic programming and optimal control

A generalized approach is taken to linear and quadratic programming in which dual as well as primal variables may be subjected to bounds, and constraints may be represented through penalties. Corresponding problem models in optimal control related to continuous-time programming are then set up and theorems on duality and the existence of solutions are derived. Optimality conditions are obtained in the form of a global saddle point property which decomposes into an instantaneous saddle point condition on the primal and dual control vectors at each time, along with an endpoint condition.
Diversity of sub-bandgap states in lead-sulfide nanocrystals: real-space spectroscopy and mapping at the atomic-scale

Colloidal semiconductor nanocrystals have emerged as a promising class of technological materials with optoelectronic properties controllable through quantum-confinement effects. Despite recent successes in this field, an important factor that remains difficult to control is the impact of the nanocrystal surface structure on the photophysics and electron transport in nanocrystal-based materials. In particular, the presence of surface defects and irregularities can result in the formation of localized sub-bandgap states that can dramatically affect the dynamics of charge carriers and electronic excitations. Here we use Scanning Tunneling Spectroscopy (STS) to investigate, in real space, sub-bandgap states in individual ligand-free PbS nanocrystals. In the majority of studied PbS nanocrystals, spatial mapping of electronic density of states with STS shows atomic-scale variations attributable to the presence of surface reconstructions. STS spectra show that the presence of surface reconstructions results in formation of surface-bound sub-bandgap electronic states. The nature of the surface reconstruction varies depending on the surface stoichiometry, with lead-rich surfaces producing unoccupied sub-bandgap states, and sulfur-rich areas producing occupied sub-bandgap states. Highly off-stoichiometric areas produce both occupied and unoccupied states showing dramatically reduced bandgaps. Different reconstruction patterns associated with specific crystallographic directions are also found for different nanocrystals. This study provides insight into the mechanisms of sub-bandgap state formation that, in a modified form, are likely to be applicable to ligand-passivated nanocrystal surfaces, where steric hindrance between ligands can result in under-coordination of surface atoms.
Assessing the Effects of Health Promotion in Worksites: A Review of the Stress Program Evaluations

In a recent issue of Health Education Quarterly, Chen( I ) reviewed the evaluations of worksite health promotion programs published in health education journals from 1980 through June 1983. He found few evaluations in the literature that used either quasi-experimental or experimental designs. This paper reviews the evaluations of stress reduction programs in the worksite, most of which were either published outside of health education journals or unpublished. Over one- half of the studies used either experimental or quasi-experimental designs in the evaluations. This suggests that reviews of worksite health promotion program evaluations must encompass journals from a variety of disciplines. Recommendations for improving the evaluations of stress reduction programs in the worksite are included.
Serotonin transporter and BDNF polymorphisms interact to predict trait worry

Background and Objectives: Excessive worry is associated with a range of psychological disorders. While previous studies have examined genes associated with a range of different anxiety phenotypes, none have explored genes specifically associated with the general tendency to worry. Design: The present study tested associations between trait worry and functional polymorphisms of three candidate genes: the serotonin transporter-linked polymorphic region (5-HTTLPR) of the SLC6A4 gene, the Val66Met region of the brain-derived neurotrophic factor (BDNF) gene, and the Val158Met region of the catechol-O-methyltransferase (COMT) gene. Methods: A heterogeneous sample of adult participants (n = 173) completed the Penn State Worry Questionnaire (PSWQ) and provided DNA samples for genotyping. Results: Results revealed a significant interaction between 5-HTTLPR and BDNF genotypes predicting levels of worry. Specifically, there was a significant positive association between 5-HTTLPR short alleles and PSWQ scores, but o...
Reference plane parasitics modeling and their contribution to the power and ground path "effective" inductance as seen by the output drivers

Modeling of the current distribution in package reference (power and ground) planes and the extraction of the associated parasitics are presented. Electrical network and equivalent circuit are developed to model the chip-package interface including the effects of V/sub DD//V/sub SS/ planes. For single- and multichip packages, methods of calculating the "effective" inductance (L/sub eff/) as seen by the output drivers from their on-chip V/sub DD/ and V/sub SS/ buses to the tip of the package pin are explained. Variations from the conventional method (where all connections are assumed identical) of calculating L/sub eff/ are analyzed. Closed-form equations are given to estimate the simultaneous switching noise (SSN) on the on-chip V/sub DD//V/sub SS/ buses for packaged CMOS circuits. The contribution of reference plane (with and without perforation) parasitics on the SSN are investigated. Optimal package pin placement to minimize the plane inductance is discussed. >
Wireless sensor networks: a survey

This paper describes the concept of sensor networks which has been made viable by the convergence of micro-electro-mechanical systems technology, wireless communications and digital electronics. First, the sensing tasks and the potential sensor networks applications are explored, and a review of factors influencing the design of sensor networks is provided. Then, the communication architecture for sensor networks is outlined, and the algorithms and protocols developed for each layer in the literature are explored. Open research issues for the realization of sensor networks are also discussed.
Atoh1-dependent rhombic lip neurons are required for temporal delay between independent respiratory oscillators in embryonic mice

All motor behaviors require precise temporal coordination of different muscle groups. Breathing, for example, involves the sequential activation of numerous muscles hypothesized to be driven by a primary respiratory oscillator, the preBotzinger Complex, and at least one other as-yet unidentified rhythmogenic population. We tested the roles of Atoh1-, Phox2b-, and Dbx1-derived neurons (three groups that have known roles in respiration) in the generation and coordination of respiratory output. We found that Dbx1-derived neurons are necessary for all respiratory behaviors, whereas independent but coupled respiratory rhythms persist from at least three different motor pools after eliminating or silencing Phox2b- or Atoh1-expressing hindbrain neurons. Without Atoh1 neurons, however, the motor pools become temporally disorganized and coupling between independent respiratory oscillators decreases. We propose Atoh1 neurons tune the sequential activation of independent oscillators essential for the fine control of different muscles during breathing. DOI: http://dx.doi.org/10.7554/eLife.02265.001
Children's Role in Generating Social Capital

Using data from the 500 Family Study, this study examines how adolescents contribute to their families' social capital. An instrumental variable model reveals that adolescents' social involvement has a positive effect on social support from sources outside the family, suggesting that parents connect to other parents in the community through their children. This finding provides an interesting revision to Coleman's model of social closure. It indicates that rather than being solely the outcome of parents' investments, the creation of social capital is a process also mediated by the children themselves, who can act as motivators of network building for their parents.
Thermo-responsive polymer grafted aluminum surface to actively modulate water wettability

Thermo-responsive wettability is studied for adaptive surface, which can potentially help to enhance the performance of thermal devices under various operation conditions. Poly(N-isopropylacrylamide) or PNIPAAm polymer brush can be grafted onto solid surfaces so that at temperatures below the lower critical solution temperature (LCST), the surface is hydrophilic, while at temperatures above LCST, it automatically becomes more hydrophobic. In this study, PNIPAAm is grafted on to aluminum alloy 6061, which is a multipurpose alloy commonly used in thermal mechanical systems. It is demonstrated by water static contact angle experiment at varies temperature that, the surface is hydrophobic at temperatures above LCST, and hydrophilic below LCST. The results are compared with bare aluminum surface at similar temperatures. Grafting PNIPAAm polymer brush on roughened aluminum surface would result in the ability to automatically switch between superhydrophobic state and superhydrophilic state in response to temperature change.Copyright © 2015 by ASME
A Design Environment for Performance Modeling and Analysis of Aero Engine Lubrication Systems

This paper presents the overview and capability of design Environment for performance modeling and analysis of aero engine lubrication systems. The design environment is implemented as an intuitive and easy to use toolbox implemented within the commercial off-the-shelf (COTS) simulation software environment MATLAB/Simulink®. The toolbox consists of a library of predefined reusable/generic lubrication system components like flow resistance elements, pumps and orifice. The component behavior is modeled mathematically using first principles and component characteristics. The developed components have been extensively verified & validated with actual hardware test data covering multiple test points in the flight envelope and also different failure modes of the system. The verification & validation methodology and the results of the component tests, is not the subject of the paper. The aero engine lubrication system is modeled by connecting the components drawn from the library to form a network consisting of nodes and flow paths. The solver implemented computes the unknown pressure and flow values in the lubrication circuit. The design environment has been used to perform steady state performance analysis of aero engine lubrication system. It has additional capability to perform parametric studies, trade studies, design exploration, analyzing simulation results and automated report generation, which will be described in the paper. The flexible software architecture and modular programming techniques has delivered the significant benefit of component models reuse. The generic nature of the toolbox can be exploited to perform system modeling and analysis of any hydraulic system.Copyright © 2013 by ASME
Luminescent organoboron ladder compounds via directed electrophilic aromatic C–H borylation

Luminescent B–N containing conjugated ladder compounds are prepared by directed electrophilic aromatic substitution. Negishi cross-coupling reaction of 2,7-dibromo-9,9-dihexylfluorene with 6-methylpyridin-2-yl(pivaloyloxy)zinc furnishes the dipyridylfluorene precursor (1) in 44% yield. Compound 1 is then subjected to electrophilic borylation with BBr3 in the presence of iPr2NEt as a bulky base to give the tetra-coordinate ladder-type organoboron species 2-Br. Arylation of 2-Br is accomplished by addition of Ph2Zn or C6F5Cu in toluene furnishing the targeted bis(pentafluorophenyl)borane and diphenylborane species 2-Ar (Ar = Ph, C6F5) in 53 and 44% yield respectively. The products show a strong blue emission and undergo multi-step reversible reduction and oxidation processes. The effect of fluorination of the pendant aryl groups on the electronic structure is further examined by DFT methods.
Discrimination by the Parasite, Apanteles melanoscelus, Between Healthy and Virus-Infected Gypsy Moth Larvae

Lymantria dispar L. larvae infected with the gypsy moth nuclear polyhedrosis Virus were exposed to Apanteles melanoscelus (Ratzeburg) females, separately and in combination. with noninfected larvae. Significant differences established among the number of parasite-host contacts and percent ovipositional attempts observed under various treatments indicated that the parasites preferred noninfected larvae, making fewer efforts to parasitize virus-infected individuals. Since the noninfected and virus-infected larvae were different in a number of ways, several factors may have contributed to the behavioral discrimination evidenced.
Pediatric small bowel transplantation: techniques and outcomes

Intestinal failure remains a major cause of morbidity and mortality in children. Intestinal transplantation has emerged as a life-saving therapy for selected patients and is now a routine therapeutic tool at some transplant centers. The short-term and long-term survival rates after intestinal transp
Progress of clinical research and new formulations of paclitaxel

The results of preliminary study show that these formulations can increase the solubility of paclitaxed in water or decrease adverse reactions of the Cremophor EL. These formulations can avoid anti-allergy pretreatment in clinic and improve the advantage in pharmacokinetic, pharmacodynamics or toxicity. These formulations give a good perspective in clinical development. This article reviewed the development of some new formulations and clinical application of paclitaxel in recent years.
Traumatic brain injury, nutritional status and outcomes: a registry based cohort study

Severe Traumatic Brain Injury (TBI) is associated with hypermetabolism and increased protein catabolism. While studies suggest that nutritional support in TBI may be beneficial, to date, limited information exists regarding the association between existing malnutrition at ICU admission and patient outcomes.
How to establish a pharmacokinetics consulting service for ambulatory patients

Guidelines on establishing a pharmacokinetics consultation service are presented with emphasis on outpatient services. Need for the service must first be demonstrated, using the literature and local data on frequency of serum drug concentration monitoring for particular drugs and patient subgroups. Physician interest in the program must be determined. The pharmacist intervention may be restricted to technical interpretation of serum drug concentration data, or it can include advice based on the patient's disease process, drug effects, and the interaction between the two. In the service described, a patient interview, a chart review, drug analysis, and a written consultation were provided. A flow chart showing movement of the patient through the service was used, and the pharmacist documented the consultation in the patient's medical record, including recommendations for dosage change and follow-up. Cost items to consider in establishing the service include equipment and supplies, space, and personnel. Staff members who are responsible for serum drug analyses must meet state-specific requirements. In estimating revenues, the current number of requests for serum drug concentrations should be doubled and the institution's estimated rate of collection should be used. After the service is established, the cost of a computerized system for pharmacokinetic predictions may be justified by the increased efficiency of such a system.
From the Carolingian Empire to the Holy Roman Empire of the German Nation

Both the birth and the death dates of the medieval Empire are matters of unambiguous public record. From the day on which Pope Leo III (795–816) crowned Charlemagne (771–814), Christmas Day in the year 800, until 6 August 1806, when Napoleon’s actions caused Charlemagne’s final imperial successor, Francis II (1792–1806), to give up the imperial crown brought it to an end, there was a Roman Empire functioning in Western Europe.3 The specificity with which we know its beginning and its end, however, is misleading. To say that Francis II surrendered Charlemagne’s crown is to assume that his empire was the same as Charlemagne’s.4 Comparing maps showing the territorial extent of the two rulers’ domains would quickly disabuse the observer of the belief that Charlemagne and Francis II ruled the same domain. While Charles’s domains stretched south and west from their heartland along the Rhine, into Italy and Spain, Francis II’s empire was centered on the Austrian lands that formed the base from which the Habsburgs pushed south and east. To the extent that Charlemagne had a capital, it was Aachen, Aix-la-Chapelle, in the Rhineland, while Prague and then Vienna served the Habsburgs as capitals as they pushed into southeastern Europe.
Conceptualizing Genre-Based AWE for L2 Research Writing

This chapter presents a conceptual model for the design of genre-based AWE for L2 research writing. The model is needs-based and combines theoretical and operational frameworks. The theoretical framework underscores desired learning phenomena, drawing from Systemic Functional Linguistics (SFL), the Interactionist Approach to Second Language Acquisition (SLA), and Skill Acquisition Theory (SAT). I discuss these theories here in terms of their main tenets as well as in terms of their relevance to L2 writing, indicating areas that could be strengthened by genre-based AWE.
P-ρ-T Values for Neon from 27° to 300°K for Pressures to 200 atm Using Corresponding States Theory

Earlier compilations of neon properties by the authors[1,2] were based on the pressure-density-temperature data in the gaseous range and at saturation. To provide a basis for the extrapolation of the P-ρ-T data to lower temperatures and higher pressures, the limited experimental P-ρ-T data for neon have been compared to the P-ρ-T surfaces of nitrogen and argon by the law of corresponding states.
Predictors of Response to Behavioral Treatments Among Children With ADHD-Inattentive Type

The goal of the study was to examine baseline characteristics—child gender, IQ, age, internalizing problems, symptoms of hyperactivity/impulsivity (HI), oppositional defiant disorder, and sluggish cognitive tempo, and parent income, education, attention deficit/hyperactivity disorder (ADHD) severity, and anxiety/depression (A/D)—associated with response to behavioral treatments for ADHD, predominantly inattentive type. We employed data from 148 children (M = 8.7 years), 58% male, and 57% Caucasian in a randomized clinical trial. Positive treatment response was defined as (a) 5 or fewer inattentive symptoms and (b) a decrease of at least 3 inattentive symptoms from baseline to posttreatment. Child HI, parental A/D, and child IQ were associated with positive response, as follows: Child HI had a main effect in which it was negatively associated with treatment response (36% with 2 or more HI symptoms were positive responders vs. 59% of those with 1 or no symptoms) that was qualified by parental A/D and child ...
Grit: The Power of Passion and Perseverance

In this instant New York Times bestseller, pioneering psychologist Angela Duckworth shows anyone striving to succeed—be it parents, students, educators, athletes, or business people—that the secret to outstanding achievement is not talent but a special blend of passion and persistence she calls “grit.”Drawing on her own powerful story as the daughter of a scientist who frequently noted her lack of “genius,” Duckworth, now a celebrated researcher and professor, describes her early eye-opening stints in teaching, business consulting, and neuroscience, which led to the hypothesis that what really drives success is not “genius” but a unique combination of passion and long-term perseverance. In Grit, she takes readers into the field to visit cadets struggling through their first days at West Point, teachers working in some of the toughest schools, and young finalists in the National Spelling Bee. She also mines fascinating insights from history and shows what can be gleaned from modern experiments in peak performance. Finally, she shares what she’s learned from interviewing dozens of high achievers—from JP Morgan CEO Jamie Dimon to New Yorker cartoon editor Bob Mankoff to Seattle Seahawks Coach Pete Carroll. Among Grit’s most valuable insights: *Why any effort you make ultimately counts twice toward your goal *How grit can be learned, regardless of I.Q. or circumstances *How lifelong interest is triggered *How much of optimal practice is suffering and how much ecstasy *Which is better for your child—a warm embrace or high standards *The magic of the Hard Thing Rule Winningly personal, insightful, and even life-changing, Grit is a book about what goes through your head when you fall down, and how that—not talent or luck—makes all the difference.
DYNAMIC CHANGES OF MITRAL APPARATUS IN ACUTE MYOCARDIAL INFARCTION WITH ISCHEMIC MITRAL REGURGITATION: PROSPECTIVE 3D QUANTITATIVE ECHOCARDIOGRAPHIC STUDY

Background: Ischemic mitral regurgitation (IMR) when chronic, involves flat and adynamic mitral annulus but IMR mechanisms in acute myocardial infarction (MI) are not known. Methods: We prospectively performed 3D echocardiography (3DE) 1.8±1.0 days after a first MI, in 2 groups of consecutive
Orbiting stellar interferometer

The Orbiting Stellar Interferometer (OSI) is a concept for a first-generation space interferometer with astrometric and imaging capabilities and its responsive to the recommendations of the Astronomy and Astrophysics Survey Committee for an astrometric interferometry mission. OSI is a triple Michelson interferometer with articulating siderostats and optical delay lines. The design uses a 7 m maximum baseline and aperture diameters of 33 cm; the targeted astrometric performance is a wide-field accuracy of 5 (mu) as for 20-mag objects. The instrument would also be capable of synthesis imaging with a resolution of 10 mas. Laser metrology is used to relax structural requirements thereby reducing cost. The currently envisaged flight system fits into an Atlas II shroud, for insertion into a 900 km sun- synchronous orbit.© (1995) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
System productivity alters predator sorting of a size-structured mixed prey community

Predator–prey interactions are often size-structured and focused on smaller vulnerable size classes. Predators are also predicted to sort prey communities according to relative vulnerabilities. Increased system productivity and juvenile growth may benefit some species more than others, making relative vulnerability non-static and growth-mediated. We hypothesized that increased system productivity would weaken juvenile-stage predation generally, and potentially shift the community sorting effects of a predator. Using replicated wetland mesocosms we quantified the effects of a generalist size-specific crayfish predator (Procambarus fallax) on juveniles of two species of apple snails (Pomacea spp.) under two levels of system productivity (low vs. high). After 6 weeks of exposure, we quantified predator and productivity effects on snail survival, biomass, and composition of the assemblage. Crayfish depressed the final density and biomass of snails, and sorted the assemblage, selectively favoring survival of the native P. paludosa over the intrinsically more vulnerable invasive P. maculata. Both snails grew faster at higher productivity, but growth differentially increased survival of the invasive snail in the presence of crayfish and weakened the sorting effect. The native P. paludosa hatches at a larger less vulnerable size than the invasive P. maculata, but higher productivity reduced the relative advantage of P. paludosa. Our results are inconsistent with predictions about the sorting effects of predators across productivity gradients, because the more vulnerable prey dominated at low productivity. Our findings highlight that the relative vulnerabilities of prey to a common predator are not always fixed, but can be growth-mediated.
Poly(styrene–divinyl benzene)‐immobilized Fe(III) complex of 1,3‐bis(benzimidazolyl)benzene: Efficient catalyst for the photocatalytic degradation of xylenol orange

A polymer-supported Fe(III) complex of 1,3-bis(benzimidazolyl)benzene [PS–Fe(III)BBZNH] was used in the photodegradation of xylenol orange (XO) dye with H2O2 under UV irradiation. The catalyst was synthesized and characterized by elemental analysis, and Fourier transform infrared, far-infrared, and UV–visible–diffuse reflectance spectroscopy, Scanning electron microscopy, Brunauer–Emmett–Teller surface area measurements, thermogravimetric analysis, and magnetic measurements. An octahedral coordination around Fe(III) was confirmed by electronic spectral data, and a decrease in the intensity of the νCH2Cl peak in PS–Fe(III)BBZNH was observed compared to the polymer support; this indicated the binding of the ligand to the support. An array of experiments were carried out to assess the influence of various reaction parameters on its photocatalytic performance to ensure maximum dye degradation. The maximum photocatalytic activity was observed at pH 8 with 125 mg of catalyst, 300 ppm of XO, and 200 ppm of H2O2 with complete mineralization after 90 min, as confirmed by chemical oxygen demand measurements. Furthermore, the reactions were repeated under sunlight and under dark conditions to check the photocatalytic efficiency of PS–Fe(III)BBZNH. It displayed better catalytic performance compared than the unsupported complex, PS–Cu(II)BBZNH [Cu(II) complex of 1,3-bis(benzimidazolyl)benzene], and PS–VO(IV)BBZNH [VO(IV) complex of 1,3-bis(benzimidazolyl)benzene]. PS–Fe(III)BBZNH could be recycled for up to seven runs. A tentative mechanism involving ·OH radical was proposed. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46480.
Colonoscopy in Acute Lower Gastrointestinal Bleeding: Diagnosis, Timing, and Bowel Preparation.

Lower gastrointestinal bleeding is bleeding from a colonic source. Rapid colon purge using 4 to 6 L of polyethylene glycol followed by early colonoscopy, within 24 hours of presentation, is recommended to optimize the detection and management of bleeding sources. Although the data are mixed, early colonoscopy seems to be associated with higher detection of bleeding lesions and therapeutic interventions. There is no clear benefit for early colonoscopy in terms of reduced duration of stay, rebleeding, transfusion requirement, or surgery compared with patients undergoing elective colonoscopy. Further studies are needed to determine the effect of early colonoscopy on clinically important outcomes.
Luetic endolymphatic hydrops: Diagnosis and treatment

Luetic endolymphatic hydrops (LEH) is an effectively treatable disorder that requires astute clinical judgment to suspect, confirm, and treat. We provide a review of the literature as well as recommendations regarding the clinical management of LEH with discussion of several illustrative cases. We also give an overview of laboratory testing for the diagnosis and monitoring of the infectious process. Ultimately, the control of the otologic symptoms in LEH requires acumen on the part of the clinician.
Local Energy Trading Behavior Modeling With Deep Reinforcement Learning

In this paper, we model prosumers’ energy trading behavior, with the operation of an energy storage system, in a proposed event-driven local energy market. Through modeling local energy trading strategies of a prosumer in the proposed holistic market model, the prosumer’s decision-making process will be built as a Markov decision process with many continuous variables. Then, this decision-making process of local market participation will be solved by deep reinforcement learning technology with experience replay mechanism. Specifically, a deep Q-learning for local energy trading algorithm is modified from deep Q-network to facilitate such a decision-making within an intelligent energy system and promote prosumers’ willingness to participate in the localized energy ecosystem.
Transformation of Ammonia Fiber Expansion (AFEX) corn stover lignin into microbial lipids by Rhodococcus opacus

Abstract The lignin from AFEX-pretreated corn stover and lignin model compounds were evaluated as the sole carbon source for microbial lipid production by Rhodococcus opacus NRRL B-3311. R. opacus NRRL B-3311 could grow on the AFEX-lignin without pretreatment and accumulate lipids up to 32 mg/L in 72 h with consuming 20% of the total lignin. The lipid produced from lignin had a similar fatty acid compositional profile to those of vegetable oil. Based on the metabolism analysis, R. opacus NRRL B-3311 could depolymerize AFEX-lignin and catabolize the aromatic compounds derived from the lignin. Study using aromatic model compounds found that R. opacus NRRL B-3311 preferably utilized 4-hydroxybenzoic acid as the sole carbon source over glucose, while it could not grow on p-coumaric acid or vanillin.
The Street Performer

Award for Best Creative Work 2018 Northwest Undergraduate Conference in the Humanities Loosely based off a group of female abstract artists from the late 1800s, this fictional piece is centered around the protagonist’s obsession with one particular subject in her art—the medium being filmmaking—and exploring the rather idolized projection she has created for this individual. This story attempts to examine the life of an artist who is swept up in an unconscious state of fiction, continuously re-creating and shifting her perception of people (the street performer, specifically)—often as a reflection of her own self and frustrations. This is done through the use of film, and highlighting specific images as we might see them in movies. There is a sense of self-awareness in both filming, and being watched or recorded. Faculty Sponsor: Keith Scribner
Leader Life-Span Experience Management: A Practice-Oriented Approach

Experiences accumulated over a life-time impact, form and shape a leader’s identity. Significant people, places and events influence individual leaders’ perceptions of how leaders should behave. By identifying and integrating his/her high-impact leadership relevant experiences, a leader gains a better understanding of who he/she is as a leader. This, in turn, can be used in optimizing his/her effectiveness. After reviewing some related literature, a practice-oriented framework is provided to help leaders arrive at a coherent formulation of who they are as leaders based upon relevant leadership experiences across their life span. An example application of the framework is provided. Some challenges in applying this approach are also offered.
The structure of antagonism

Abstract Several models of the lower order structure of Agreeableness have been developed, but empirically derived descriptions of this domain are largely missing. This chapter describes a recently conducted empirical examination of the factor structure of Agreeableness using items from multiple scales in order to determine the facet-level structure of the domain. Analyses were conducted on 104 items from 22 Agreeableness scales to describe factor emergence from the domain level to increasingly more specific factors. A five-factor solution was identified as most appropriate for most purposes. Identified facets in the five-factor solution were labeled Compassion, Morality, Trust, Affability, and Modesty. Factors from all levels of the construct were compared to current measures of the domain as well as several criterion variables. The results reveal how Agreeableness traits unfold from broader to more specific facets and how these traits are represented in existing measures of the domain.
Relationship of milk production, milk expected progeny difference, and calf weaning weight in angus and simmental cow-calf pairs.

Milk EPD, used to predict the milk production potential of a parent's daughters, have been reported by all major cattle breed associations. Our objectives were to determine the relationship of milk EPD of a dam to actual milk production (both fluid and components) and offspring weaning weight. Angus (AN; n = 114) and Simmental (SM; n = 82) cows were machine-milked at approximately 60, 104, and 196 d postpartum after overnight calf removal. In addition, one herd of AN was also milked at approximately 35 and 145 d postpartum. A lactation curve was fitted to these measurements to estimate total milk production during lactation. Simple correlations between 205-d total milk yields (TMY) and adjusted 205-d calf weaning weight (WW) were .30 (P < .001) and .47 (P < .001) for AN and SM, respectively. Furthermore, milk EPD was positively correlated to adjusted WW (r = .38 P < .001; r = .39, P < .001) and TMY (r = .32, P < .001; r = .44, P < .001) for AN and SM cows, respectively. A 1-kg change in TMY changed WW by .014 +/- .006 kg (P < .001) in AN and by .032 +/- .009 kg (P < .001) in SM. A 1-kg change in milk EPD resulted in a 4.85 +/- 1.14 kg change in WW (P < .001) in AN and a 3.74 +/- 1.73 kg (P < .05) change in SM. Corresponding changes in TMY were 42.1 +/- 16.6 kg (P < .01) and 69.3 +/- 16.0 kg (P < .001) for AN and SM, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
41. THE EFFECT OF AN ACADEMIC HALF DAY CURRICULUM ON ITE SCORES AND RESIDENT SATISFACTION WITH BOARD PREPARATION

Background Resident didactics often occur during noon conferences. In 2017, the New York University School of Medicine Pediatric Residency Program transitioned from daily noon conferences to a weekly 3-hour Academic Half Day (AHD). While internal medicine residency programs have shown an association between AHD and higher in-training exam (ITE) scores 1 , the impact of AHD on pediatric resident ITE scores or satisfaction with preparation for the General Pediatric Board Exam is not well studied. Objective To investigate the impact of AHD on resident ITE scores and satisfaction with board preparation. Methods We compared PGY2 raw ITE scores between the 2018 and 2019 graduating resident classes using a 2-sample t-test. We performed the same comparison for the PGY3 raw ITE scores. For the year between exams, the Class of 2018 received noon conferences, while the Class of 2019 received AHD. To assess resident satisfaction with board preparation, residents completed a survey prior to starting AHD and after 1 year. Satisfaction was reported on a Likert scale. Responses were categorized as “agree”, “neutral”, or “disagree” and analyzed with a chi-square test. Results There was no significant difference between the mean PGY2 ITE scores for the Class of 2018 (63.8 +/- 7.2) and 2019 (63.3 +/- 7.2) (p=0.8). The Class of 2019 had a significantly higher PGY3 ITE score (73.8 +/- 5.2) than the Class of 2018 (67.7 +/- 7.4) (p=0.01). When rating the statement “the current curriculum prepares me to take the boards”, the percent of residents responding “agree” was 18% pre-AHD and 73% 1-year post-AHD. The association between initiation of AHD and satisfaction with exam preparation was statistically significant (X2=23.1, p Conclusion The transition to an AHD had a positive impact on ITE scores and resident satisfaction with board preparation.
Ultra-Wideband Underwater Backscatter via Piezoelectric Metamaterials

We present the design, implementation, and evaluation of U2B, a technology that enables ultra-wideband backscatter in underwater environments. At the core of U2B's design is a novel metamaterialinspired transducer for underwater backscatter, and algorithms that enable self-interference cancellation and FDMA-based medium access control. We fabricated U2B nodes and tested them in a river across different weather conditions, including snow and rain. Our empirical evaluation demonstrates that U2B can achieve throughputs up to 20 kbps, an operational range up to 62 m, and can scale to networks with more than 10 nodes. In comparison to the state-of-the-art system for underwater backscatter, our design achieves 5x more throughput and 6x more communication range. Moreover, our evaluation represents the first experimental validation of underwater backscatter in the wild.