cssi/SciSciGPT-SciSciNet huggingface dataset:
Development of a Selective Broth Medium for the Detection of Injured Campylobacter jejuni by Capacitance Monitoring

The purpose of these studies was to develop a conductimetric method for the rapid detection of Campylobacter jejuni. Numerous basal medium components were analyzed to develop a growth-enhancing broth medium for detection of freeze-injured Campylobacter cells using a conductimetric system. The final medium was composed of a modified Campy-Line agar from which the agar and triphenyltetrazolium chloride were removed and the amino acid, L-arginine was added. Pure isolates of C. jejuni. (frozen and thawed to produce stressed cells) were utilized to test the detection methodology. Monitoring of significant changes in the capacitance signal was found suitable for detection of Campylobacter proliferation. Using stressed pure cultures, Campylobacter growth was repeatedly detected at very low inoculum levels (about one cell per well). There was a direct linear relationship between detection times (DTs) and the initial inoculum level. For example, using a single strain, the mean DT (n = 20) at the 10 CFU/ml inoculum level was 28.6 h, with 100% of the inoculated wells detecting. The mean DTs at the 100, 1,000, and 10,000 CFU/ml inoculum levels were 24.9, 21.4, and 17.0 h, respectively. This study demonstrates that conductimetric methods can be utilized for the rapid detection of C. jejuni.
Bromoacetamido-Analogs of Indomethacin and Mefenamic Acid Affinity-Label Prostaglandin H2 Synthase at Two Sites

Prostaglandin H2 (PGH) synthase (EC 1.14.99.1) catalyzes the bis-dioxygenation of arachidonic acid to yield PGG2 (cyclooxygenase reaction) and the peroxidative cleavage of PGG2 to yield PGH2 (peroxidase reaction). PGH synthase (Mr: 72 kDa) functions as a homodimer and is a target for nonsteroidal antiinflammatory drugs (NSAIDs), which inhibit the cyclooxygenase reaction only.
Utilisation of medications to reduce symptoms in children with postural orthostatic tachycardia syndrome.

BackgroundPostural orthostatic tachycardia syndrome encompasses multiple disabling symptoms that interfere with daily activities. Non-pharmacologic approaches can be insufficient and can require adjunctive medications to manage symptoms. Minimal data exist in the literature on medication outcomes in these patients. We reviewed our database for medication management outcomes.Materials and MethodsPatients aged 18 years and younger at initial diagnosis met the inclusion criteria. All prescribed patient medications were extracted from the electronic health record, excluding medications for unrelated symptoms or comorbid diseases. Medications were grouped by symptom class consistent with our programme utilisation protocol. Within symptom classification, therapy was deemed successful when a specific dose was prescribed at least five consecutive times without changes; this was confirmed by chart review. Individual medications and overall percentage of successful therapies within symptom classifications were assessed, with further analysis by gender. t-Test, χ2, and Mann–Whitney U-test were used to assess for differences in specific variables, as appropriate.ResultsA total of 708 patients met the study criteria. The percentage of patients with effective therapy by symptom includes light-headedness (52.2%), headache (48.2%), nausea (39.1%), dysmotility (43.4%), pain (53.4%), and insomnia (42.8%). Insomnia therapy was better for females; all other therapies showed no gender difference. The median number of therapies prescribed per patient per symptom was 2 for light-headedness, headache, and insomnia, and 1 for nausea, dysmotility, and pain.DiscussionSymptoms associated with this disorder can be effectively managed with various medications. Further randomised studies are needed to better ascertain true efficacy compared with placebo.
Bartonella henselae in a dog with ear tip vasculitis.

Background Bartonella henselae, a Gram-negative, zoonotic, alpha-proteobacteria has been previously implicated in association with cutaneous vasoproliferative lesions (bacillary angiomatosis), nodular panniculitis and multifocal erythema (erythema multiforme) in dogs. Objective Describe clinical, microbiological and histological lesions in a dog with ear margin vasculitis and B. henselae infection. Animals A 12-month-old, specific pathogen-free intact female beagle dog maintained in a vector-free laboratory animal resource facility. Methods and materials Bartonella and Rickettsia serological evaluation, Bartonella and Rickettsia PCR, Bartonella alpha-proteobacteria growth medium (BAPGM) enrichment blood culture/PCR, histopathological investigation and confocal immunohistochemical evaluation. Results Serological investigation (seroreversion) and PCR testing of aural tissue biopsies failed to support Rickettsia rickettsii as a cause of the aural vasculitis; however, B. henselae, genotype San Antonio 2 DNA was amplified and sequenced from both ear tip margins and from normal-appearing abdominal skin. Seroconversion to B. henselae was documented retrospectively by IFA testing. Bartonella henselae organisms were visualized by confocal immunostaining within all three biopsies. Histopathology revealed small vessel necrotizing vasculitis and dermal necrosis. Bartonella henselae seroreversion and complete resolution of skin lesions occurred in conjunction with administration of oral doxycycline and enrofloxacin for six weeks. Conclusions and clinical importance Bartonella henselae is an emerging zoonotic pathogen that has been associated with leucocytoclastic vasculitis in humans and may have had a contributing or causative role in the development of the cutaneous aural margin vasculitis in this beagle.
AORTIC ROOT DILATION IN ADULT MARFAN PATIENTS: DOES AORTIC ROOT STIFFNESS MATTER?

Marfan syndrome is a connective tissue disorder that can lead to progressive aortic root dilation, aortic dissection, and death. Outcomes have improved with aortic root (AoR) monitoring and prophylactic AoR surgery, however, AoR size remains an insufficient predictor of rate of dilation or
Assessment of Aerocapture for Orbit Insertion of Small Satellites at Mars

Small satellites may provide a low-cost platform for targeted science investigations in the Mars system. With current technology, small satellites require ride shares with larger orbiters to captur...
A Systematic Review Investigating the Relation between Animal-Source Food Consumption and Stunting in Children Aged 6-60 Months in Low and Middle-Income Countries

Animal-source foods (ASFs) are a food group of interest for interventions aimed at reducing stunting and other inadequate growth measures in early childhood. The aim of this systematic review was to examine the relation between ASF consumption and stunting in children aged 6-60 mo in low- and middle-income countries (LMICs). The secondary aim was to examine the relation between ASF consumption and other indicators of growth and development (length/height, weight, head circumference, and anemia). A search of the peer-reviewed and grey literature published from January 1980 to June 2017 was conducted. Databases searched included CINAHL, Embase, Global Index Medicus, PubMed, and Web of Science. There were 14,783 records and 116 full text articles dual screened; 21 studies were included in the review and were dual evaluated for risk of bias (RoB). The relation between ASF and stunting (length- or height-for-age z-score←2) was examined in randomized-controlled trials [(RCTs), n = 3] and cross-sectional studies (n = 4) only; ASF reduced stunting in 1 RCT and was associated with reduced stunting in 1 cross-sectional study. We did not identify any longitudinal cohorts that examined this relation. The relation between ASF and secondary indicators length/height, weight, head circumference, and anemia were largely nonsignificant across study designs. The intervention/exposure, comparator, outcome measures, methods, and analyses were highly heterogeneous. Although we did not find a consistent relation between ASF consumption and our primary and secondary outcomes, this may have been a function of inconsistencies in study design. Foods in the whole diet, particularly combination dishes, are inherently difficult to assess. To quantitatively assess the relation between ASF and stunting and other indicators of growth and iron status in early childhood, future research should provide consistency in the definition and quantification of the exposure and outcomes allowing for interstudy quantitative comparisons.
Lifetime of the metastable P 2 3 and P 0 3 states of rare-gas atoms

The lifetimes of the $^{3}P_{2}$ states of Ne, Ar, Kr, and Xe are calculated by considering the spin-dependent magnetic-quadrupole ($\mathrm{SM}2$) radiative transition to the $^{1}S_{0}$ state as the decay mechanism. By expressing the $\mathrm{SM}2$ operator as a contraction of the spin magnetic dipole and the electric dipole, the lifetime of the $^{3}P_{2}$ state can be expressed very simply in terms of that of the $^{1}P_{1}$ state. With the known lifetimes of the $^{1}P_{1}$ state, the calculated lifetimes of the $^{3}P_{2}$ states are 24.4, 55.9, 85.1, and 149.5 sec, respectively, for Ne, Ar, Kr, and Xe. The lifetime of the $^{3}P_{0}$ state is calculated by considering both the magnetic-dipole ($M1$) transition to $^{3}P_{1}$ and the electric-quadrupole ($E2$) transition to $^{3}P_{2}$ as the decay mechanism. The calculated lifetimes are 430, 44.9, 0.488, and 0.078 sec, respectively, for Ne, Ar, Kr, and Xe. These calculated lifetimes are above the lower limits of the experimental lifetimes measured by Van Dyck, Johnson, and Shugart.
"Revisiting J.S. Mill's Case for Civil Dialogue in the Age of Partisan Division: Its Utility for Teaching Political Theory" Prepared for Civic Engagement TLC2020

John Stuart Mill’s essay, On Liberty (1859) grapples with a familiar problem; namely, how to determine “the nature and the limits of power which can be legitimately exercised by society over the individual.” Today, even more than in Mill’s time, with the proliferation of partisan websites and social media outlets, it is tyranny, not merely of princes, but of polarized public opinion expressed in ‘virtual’ communities, confirming rather than challenging social and political beliefs that—we must now be on guard. Mill’s case in seeking truth depends on vigorous debate, but applying his liberal philosophy may be easier said than done. This paper considers both the possibilities and limitations of putting his philosophy of education into practice when using a tutorial method for teaching political theory.
Synthesis of 6-(Fluoromethyl)-19-norcholest-5(10)-en-3-ol, a fluorine analogue of NP-59, Using TBAF(pin)2

1607 Objectives: The scintiscanning agent NP-59, [131I]6-(iodomethyl)-19-norcholest-5(10)-3-ol, was developed in the 1970’s for adrenal imaging. It is utilized in the imaging of adenomas and carcinomas of the adrenal gland cortex to detect: Cushing9s syndrome, primary aldosteronism, hyperandrogenism, and euadrenal tumors[1-2]. With the advent of PET imaging, there had been an effort in the late 1970’s and early 1980’s to develop an 18F labelled analogue of NP-59 (FNP-59) for use as a PET imaging agent. However, those efforts to prepare the analogue failed due to undesired elimination reactions and unexpected rearrangements observed while trying a wide variety of fluorinating conditions (e.g. silver fluoride, FAR, DAST, and FPA) [3]. Here, we report the synthesis of the FNP-59 using the recently developed, mild fluorinating reagent, that is less prone to produce elimination reactions in the preparation of primary fluorides, TBAF(pinacol)2 [4]. Methods: NP-59 was synthesized according to the previous literature. NP-59 was then treated with acetic anhydride in dichloromethane in the presence of 4-dimethylaminopyridine and pyridine to afford the acetyl protected intermediate (1). This was then heated at reflux in acetonitrile with silver tosylate to give the acetyl protected tosylate analogue (2). The tosylate was then heated in acetonitrile with TBAF(pinacol)2, yielding the acetyl protected FNP-59 (3). Finally, the protected material was treated with potassium carbonate in dichloromethane and methanol, to provide FNP-59. Results: The four step synthesis of FNP-59 from NP-59 proceeded in a 15.6% yield. The identity and purity of intermediates and final product were confirmed by standard analytical methods. The preparation of the standard has allowed us to proceed with single dose acute toxicity studies. Conclusions: With the reference standard FNP-59 synthesized and characterized, the development of a route to prepare [18F]FNP-59 is now underway. References: [1]Counsell, R. E.; et. al. STEROIDS.1970, 16, 317. [2]Sarkar, S. D.; et. al. J. Nucl. Med. 1975, 16(11), 1038-1042. [3] Kobayashi, T., et. al. Chemical and Pharmaceutical Bulletin.1982, 30(9), 3082-3087. [4] Engle, K. M., Gouverneur, V., et. al. Chem. Sci. 2015, 6(9), 5293-5302.Acknowledgements: This work was supported by the Center for the Discovery of New Medicine and a Michigan Memorial Phoenix Project SEED grant. We also want to thank Prof. Milton Gross for his advice and support of this project.
HIGH INCIDENCE OF ELEVATED BLOOD PRESSURE AMONG COLLEGIATE FEMALE ATHLETES AT PRE-PARTICIPATION PHYSICAL EVALUATION

Recently, considerable emphasis has been placed on screening athletes for risk factors associated with cardiovascular morbidity like blood pressure (BP), but there is a paucity of data among female collegiate athletes. This study characterizes the BP of collegiate female athletes at the time of pre-
What to Do When Evidence-Based Treatment Manuals Are Not Enough? Adapting Evidence-Based Psychological Interventions for Primary Care

Abstract Significant barriers exist in accessing high-quality, evidence-based psychological interventions in traditional mental health settings. Adapting these interventions for delivery within primary care is particularly advantageous given that the majority of individuals with mental health conditions are more likely to seek care in this environment much earlier in their course of illness than in specialty mental health clinics. The aim of this paper is to summarize efforts at Mayo Clinic to develop and disseminate evidence-based psychological interventions across multiple primary care clinics. Adaptations aimed at improving access to care, enhancing the quality of care, and incorporating a system of measurement-based outcomes are unique features that are essential to the sustainability and advancement of integrated behavioral health programs within primary care.
Determinants of the Usefulness of Inside Debt in Debt Contract Design

Evidence shows that managers’ debt-like compensation (i.e., inside debt) aligns their incentives with lenders’, reducing the agency cost of debt. We examine how changes in the contracting environment affect the use of inside debt in debt contracting. We find evidence of reduced reliance on inside debt for debt contracting when borrowers have credit constraints, consistent with a shift in bargaining power to lenders, and when firms experience financial distress, consistent with increased agency costs when bankruptcy is more probable. We detect reduced reliance on inside debt for debt contracting during the financial crisis and during shocks to industry demand, two plausibly exogenous shocks to firms’ contracting environments. In total, the results suggest that the role of inside debt changes predictably with the contracting environment.
In Situ Optical Quantification of Extracellular Electron Transfer from Shewanella oneidensis using Plasmonic Metal Oxide Nanocrystals

Abstract Extracellular electron transfer (EET) is a critical form of microbial metabolism that enables respiration on a variety of inorganic substrates, including metal oxides. For this reason, engineering EET processes has garnered significant interest for applications ranging from bioelectronics to materials synthesis. These applications require a strong understanding of electron flux from EET-relevant microbes. However, quantifying current generated by electroactive bacteria has been predominately limited to biofilms formed on electrodes, which require long incubation times, electrode colonization, and convolute contributions to EET from planktonic cells. To address this, we developed a platform for quantifying time-resolved EET flux from cell suspensions using aqueous dispersions of plasmonic tin-doped indium oxide nanocrystals. Tracking the change in optical extinction during electron transfer and fitting the optical response to a free electron model enabled quantification of current generation and electron transfer rate constants from planktonic Shewanella oneidensis cultures. Using this method, we differentiated between starved and actively respiring S. oneidensis, and between cells of varying genotype using an EET knockout strain. In addition, we quantified current production ranging from 0.12 – 0.68 fA • cell−1 from S. oneidensis cells engineered to differentially express a key EET gene using an inducible genetic circuit. Overall, our results validate the utility of colloidally stable plasmonic metal oxide nanocrystals as quantitative biosensors in native biological environments and contribute to a fundamental understanding of planktonic S. oneidensis electrophysiology using simple in situ spectroscopy.
Engaging students in planning for superfund site remediation and redevelopment.

Abstract Communities with contaminated lands are also often the most vulnerable to the impacts of a changing climate such as sea-level rise, increased temperatures, and extreme storms and hurricanes due to socio-economic and historic reasons – some of the very factors that enable the creation of these contaminated sites in these communities. In spite of, and arguably because of, this double exposure and impact, the ability of these communities to clean up and reuse their contaminated lands has not kept up with their need. Researchers have often attributed this discrepancy to a lack of technical capacity and human resource. To address this lack, since January 2018, students enrolled in planning-related courses offered by the University of West Florida Department of Earth and Environmental Sciences have engaged with stakeholders on the redevelopment of superfund sites located in Pensacola, FL under the auspices of the USEPA's College Underserved Community Partnership Program. The engagement centered on the reuse of two of these superfund sites for the betterment of the stakeholders' socio-economies and their biophysical environments. I focus in this paper on four examples of engaging with students in planning for superfund site remediation and redevelopment. The examples are of engaging with county staff; collaboratively engaging with city staff and a private firm; engaging with county commissioners; and engaging with a private firm between two superfund sites over the course of one year. I highlight the contextual, unique needs, of each stakeholder group yet emphasize the applicable lessons across all four examples. I also focus on best practices to develop plans and outlines for mutually beneficial products and outcomes for both students and stakeholder groups in the process of land revitalization.
Entrepreneurship and the Market Process

This chapter provides the analytical background for the chapters contained in this volume and reviews the foundational literature on entrepreneurship and the market process.
Scientific teams and institutional collaborations: Evidence from U.S. universities, 1981-1999

Abstract This paper explores recent trends in the size of scientific teams and in institutional collaborations. The data derive from 2.4 million scientific papers written in 110 top U.S. research universities over the period 1981–1999. The top 110 account for a large share of published basic research conducted in the U.S. during this time. We measure team size by the number of authors on a scientific paper. Using this measure we find that team size increases by 50% over the 19-year period. We supplement team size with measures of domestic and foreign institutional collaborations, which capture the geographic dispersion of team workers. The time series evidence suggests that the trend towards more geographically dispersed scientific teams accelerates beginning with papers published at the start of the 1990s. This acceleration suggests a sharp decline in the cost of collaboration. Our hypothesis is that the decline is due to the deployment of the National Science Foundation's NSFNET and its connection to networks in Europe and Japan after 1987. Using a panel of top university departments we also find that private universities and departments whose scientists have earned prestigious awards participate in larger teams, as do departments that have larger amounts of federal funding. Placement of former graduate students is a key determinant of institutional collaborations, especially collaborations with firms and with foreign scientific institutions. Finally, the evidence suggests that scientific output and influence increase with team size and that influence rises along with institutional collaborations. Since increasing team size implies an increase in the division of labor, these results suggest that scientific productivity increases with the scientific division of labor.
Lee Quede: Massacres in 1948 and the Influence of Diego Rivera

The article presents a comprehensive and novel look at the Korean painter Lee Quede (1913–1965), with particular emphasis on his People series (1948). Lee’s work draws direct influence from Kitagaw...
Images and Sequences

Previous chapters have laid out the foundations of AI for us in terms of the overall training process. We have an insight into the expressive power of deep neural networks, for which we used FFN with several hidden layers of neurons which are fully connected. Before the dawn of AI, shallow FFNs with one hidden layer were used in the feature space by ML practitioners. However they don’t work well for images and sequences.
Research Training During Psychiatric Residency A Personal Reflection

There is a dearth of excited, committed, welltrained clinical investigators in psychiatry. This is despite a rapid growth in the scientific foundations of the field over the past 20–30 years. It is also despite substantial improvements in research methods and funding. All areas of psychiatric clinical investigation are in need of researchers, areas including, but not limited to, methods development, population epidemiology, clinical epidemiology, clinical genetics, brain imaging, clinical psychopharmacology, clinical trials, and outcomes research. Barriers to the recruitment of clinical investigators have been discussed by many publications, roundtables, and meetings; these barriers include the complexities of psychiatry as a field, difficulties in quantifying and studying psychiatric disorders, intricate human-subjects issues, negative perceptions from other branches of medicine, and others. Yet, a message that seems to come across over and over again is that the most opportune time to cultivate a future psychiatric clinical investigator is during residency. It is during this time that the psychiatrist-trainee is immersed in learning about psychiatry, taking care of patients, reading the literature, and attending teaching conferences, all the while interacting with senior psychiatrists and other teachers. This immersion is occurring in a variety of environments, but, more often than not, in an academic environment where research is happening alongside clinical care. The purpose of this essay is to reflect upon my own experience in psychiatric residency and on how it influenced my development as a clinical investigator. It is also to reflect upon the key elements that need to be in place during psychiatric residency in order to entice residents into clinical investigation. Background
The Textbooks-in-College-Libraries Mystery

This article investigates whether textbooks are appropriate for a college library collection. Collection development policies and other professional commentary offer little clear direction since they do not define what a textbook is. Evidence and opinion suggest that it would be wise to eliminate the ''textbook'' label, treat these resources as ''books,'' and apply to them the standard collection development criteria.
Sexual Use and What to Do About it

The 18th-century German philosopher Immanuel Kant described human sexuality in hideous terms; on his view, by their essence sexual desire and sexual activity are always morally suspicious. Given Kant's metaphysics or anthropology of human sexuality, all sexual activity apparently conflicts with the Second Formulation of his Categorical Imperative and hence is morally wrong. An analytic typology of solutions to this problem is proposed and within this typology recent philosophical ethics of sexuality are critically discussed. Kant's stated solution, the Biblical idea that marriage unites the two persons into one, is not really the solution he proposes; it is more subtle than that, and depends instead on the duty not to harm the self.
Circuit design issues for the POWER4 chip

POWER4 is a next-generation system-on-a-chip design, incorporating two microprocessor cores, 1.44 MB L2 memory, and L3 directory and memory controller, all on one die.[1-3] It contains over 170 million transistors, and operates at frequencies in excess of 1.3 GHz in IBM's 0.18 /spl mu/m silicon-on-insulator (SOI) technology.[4] Along with the usual area, power, and frequency concerns, the circuit design leaders of this chip faced many difficult and, in some cases, unique challenges including the definition and application of global clocking and latching styles, rigorous definitions of allowed circuit styles, rules, and methodologies, and special considerations for SOI-related phenomena. The circuit design "rules and regulations" had to be carefully crafted and balanced to allow achievement of the project's aggressive design goals, while at the same time taking the utmost care to minimize the risks imposed by the size of the chip and its logical complexity, new features, aspects and characteristics of the SOI technology, the number of designers involved and their varying levels of skill and experience, and the necessity of maintaining strict adherence to a tight product delivery schedule. This paper describes the circuit design of the POWER4 chip, covering in detail some of the solutions adopted, as well as the techniques and methodologies employed to optimize the design.
Temperature sensing: The direct road to information

The retrievability of detailed temperature soundings from remote measurements of emission spectra depends not so much on how the data are treated as on what the data are. It is shown that the shape of the weighting functions depends on the nature of the pressure and temperature dependence of the transmittance, which differ from one part of the spectrum to another as well as with spectral resolution. It is shown that careful selection of channels results in much narrower weighting functions than those corresponding to channels that have actually been used.
The Archaeology Education Handbook: Sharing the Past with Kids

The Archaeology Education Handbook: Sharing the Past with Kids. Karolyhn Smardz and Shelley J. Smith. eds. Walnut Creek, CA: AltaMira Press, 2000. 447 pp.
Strategies for Helping Early School-Aged Children with Oppositional Defiant and Conduct Disorders: The Importance of Home-School Partnerships

This article provides a brief review of the diagnosis, developmental progression, and etiology of oppositional defiant and early-onset conduct disorders (ODD/CD) in children. Family and school beha...
Formation of Fatty Acid Methyl Esters During Gas Chromatography Using Trimethylanilinium Hydroxide

Abstract Fatty acid methyl esters may be formed by dissolving the fatty acids in a 0.2 M solution of trimethylanilinium hydroxide in methanol and injecting the solution into a gas chromatograph. The reaction is rapid and quantitative, and the reagent appears to be less hazardous than diazomethane.
Oscillation During Switching Transient Of Acousto-Optic Bistable Device With Dual Feedback: Indication Of Chaos And Output-Input Characteristics For Continuous Oscillation Mode

An optical switch has been designed, built, and tested and is based upon an acousto-optical modulator with dual feedback and a short carrier round trip time. It is observed that: (1) the switching transient itself displays oscillatory behavior; (2) the pre-and post-switching stable states seem to display chaos; and (3) slight variation in feedback will convert the switch to an optical oscillator/modulator with a characteristic zigzag output-input curve.
Electron microscopic study of the lymphocytes capable of binding antigen-antibody-complement complexes.

Abstract Complement-receptor-lymphocytes (CRL), cells capable of forming rosettes with sheep erythrocytes (E) complexed with anti-erythrocyte antibody (A) and complement (C) were compared with non-CRL with respect to fine structures and contact with EAC complexes. Observations were made upon rosettes formed by sensitized erythrocytes (EAC) with CRL from spleen and lymph node after 30 min of incubation at 37 ° c, upon CRL isolated from rosettes, and non-CRL from spleen and lymph nodes. Multiple contacts, both broad and point-like occurred between EAC and CRL. Small and medium-sized lymphocytes accounted for 98% of CRL from lymph nodes and 89% from spleen. Morphologically CRL from spleen and lymph nodes and non-CRL are not distinguishable.
The quantitative methods component in social sciences curricula in view of journal content

What level of quantitative methods (or applied statistical analysis) should graduate students in the social sciences be prepared to master, if they are to be competitive in the job market? In the age of information technology, more data, in survey or other form, about any imaginable topic exist than ever before. Empirical analysis on the basis of more advanced quantitative methods becomes more common. This study takes the perspective that graduate students in the social sciences must be prepared to read a literature that makes extensive use of quantitative methods. To quantify this dimension of the literature, top journals in economics, political science, public administration, and sociology are examined for their quantitative complexity.
Implementing a Gero-Infused Curriculum in Advanced-Level MSW Courses in Health, Mental Health and Substance Abuse: An Evaluation

This article presents evaluation results from a curricular innovation aimed at increasing the capacity of social work graduates to serve older adults in health, mental health, and substance abuse settings. Working as a team, faculty developed, incorporated, and evaluated gerontology-infused syllabi and teaching modules in multiple sections of the 3 courses, with 2 sections serving as a comparison group. Results indicated that students exposed to the gero-infused curriculum increased their age-related knowledge and self-competence from pre- to posttest, and achieved a greater increase in knowledge than did the comparison group. Implications of the findings to social work education are discussed.
Differential forms — Cartan to de rham

ω = Zf«v«2...«k dxai dx^.^dx^. They have played a major role in such fields as differential equations, algebraic topology, and Lie groups during the twentieth century. In an earlier paper [Ka] I discussed their early history from their origins in the 18th century through the work of PoiNCARE and Volterra at the end of the 19th century, exploring particularly the notions of line and surface integrals and the Poincare lemma and its converse. In this article I continue certain aspects of the story during the first half of the 20th century. For the convenience of the reader, I have also included some material already discussed in the earlier paper. Though they had been used for over a century, differential forms were first defined (albeit "purely symbolically") by Elie Cartan in 1899. 1 will therefore concentrate on the influences which led Cartan to his definition as well as the
Gibbs Ensemble Calculations with an Equation of State: An Application to Vapor-Liquid Equilibria

Abstract A new modification of the Gibbs ensemble Monte Carlo computer simulation method for fluid phase equilibria is described. The modification is based on a thermodynamic model for the vapor phase, and uses an equation of state to account for the weak interactions between the vapor phase molecules. Reductions in the computational time by 30–40% as compared to the original Gibbs ensemble method are obtained. The algorithm is applied to Lennard-Jones - (12,6) fluids and their mixtures and the results are in good agreement with results obtained from simulations using the full Gibbs ensemble method.
An Islamic experiment? Ottoman land policy on Crete

(1996). An Islamic experiment? Ottoman land policy on Crete. Mediterranean Historical Review: Vol. 11, No. 1, pp. 60-78.
Partial Purification of a Progesterone-Inducible Messenger RNA (Avidin) from Hen Oviduct

The messenger RNA (mRNA) for avidin, which represents less than 0.05% of the total cellular proteins, was partially purified from hen oviduct, and the presence of avidin mRNA was shown to depend upon prior stimulation by progesterone. A total nucleic acid extract was subjected to oligo (dT)-cellulose chromatography, followed by Sepharose 4B chromatography, preparative agarose gel electrophoresis, and sucrose gradient centrifugation. The relative purity of each preparation was assessed by translation in a wheat-germ system; avidin messenger RNA activity was measured by specific immunoprecipitation of synthesized proteins. Avidin mRNA was separated from the bulk of the total messenger RNA activity of the oviduct and from all ribosomal RNAs to produce greater than a 1000-fold enrichment of avidin mRNA activity compared with total cellular RNA. Based on the translation assay, the most highly purified fraction contained about 2.5% avidin messenger RNA. Avidin mRNA activity was absent in partially purified mRNA...
Electronic behavior of three oxygen non-stoichiometric Fe4+/Fe3+ oxoperovskites

Abstract For comparison with the Mn 4+ /Mn 3+ oxoperovskites at the crossover from localized to itinerant behavior of the σ -bonding e electrons, the electronic properties of three oxygen non-stoichiometric, mixed-valent Fe 4+ /Fe 3+ oxoperovskites were explored by measuring their resistivity ρ ( T ), thermoelectric power α ( T ), and magnetic susceptibility χ ( T ). Oxidation of Ca 2 Fe 2 O 5 by annealing in ozone progresses by oxygen insertion to give conductive CaFeO 3 perovskite clusters in a localized-electron, weakly oxidized brownmillerite Ca 2 Fe 2 O 5+ δ matrix. Removal of 0.12 oxygen per formula unit from La 1/3 Sr 2/3 FeO 3 lowers somewhat its cooperative disproportionation reaction, and fivefold-coordinated ions neighboring oxygen vacancies in the more ionically bonded slabs act as donors to the covalently bonded Fe(V)O 6 planes. Single-crystal SrFeO 2.83 exhibited bad-metal behavior with superparamagnetic, electron-rich fluctuations below 240 K that, on cooling below 190 K, become progressively trapped by the oxide-ion vacancies as an immobile second phase; long-range antiferromagnetic order is stabilized below a T N ≈60 K.
Amount and Distribution of Amylophosphorylase in Uterus of the Rat.

SummaryAmylophosphorylase activity of the uterus was determined both quantitatively and histochemically in castrate rats and rats treated with estrogen and/or progesterone. There was no signicant difference in enzyme activity between any of the groups of animals regardless of treatment. Moderate to strong activity was uniformly present throughout the myometrium, whereas in the endometrium there was but irregular and weak activity in the lining epithelium.
Brief Communication: The Relationship between Having a Living Will and Dying in Place

Living wills are associated with dying in a patient's residence rather than in a hospital. During advance care planning, physicians should discuss patients' preferences for location of death.
Intergenerational literacy: the use of story in family literacy instruction

Storytelling provides a valuable link between generations within a family. It also provides an innovative approach to literacy instruction for adults and children. Descriptions are given of two methods of using stories within an intergenerational family literacy programme for English-as-a-Second Language families in the United States. Folk tales and family stories are used to build the links between oral and written language, and to provide a transition from personal texts to published texts. These stories also provide a vehicle for cultural transmission between generations, and an opportunity for bilingual language and literacy development. Suggestions are developed for using this approach in Adult Basic Education (ABE) classes in other countries, including South Africa. Storytelling can also be an effective tool to foster adult basic literacy in English and/or the mother tongue.
Caregiver—child mental health: a prospective study in conflict and refugee settings

BACKGROUND: In humanitarian settings, family-level drivers of mental health are insufficiently documented; we examined the strength of caregiver-child associations with two-wave, family-level Afghan data. METHODS: We recruited a gender-balanced sample of 681 caregiver-child dyads (n = 1,362 respondents) using stratified random-sampling in government schools in Kabul (364 dyads) and refugee schools in Peshawar (317 dyads). One year after baseline, we re-interviewed 64% of Kabul and 31% of Peshawar cohorts (n = 331 dyads, 662 respondents), retaining fewer Peshawar families due to refugee repatriation. In multivariable analyses adjusted for baseline, we assessed the extent to which caregiver mental health (Self-Report Questionnaire, SRQ-20) was associated with child symptom scores of post-traumatic stress (Child Revised Impact of Events Scale, CRIES), depression (Depression Self-Rating Scale, DSRS), psychiatric difficulties, impact, and prosocial strength (Strength and Difficulties Questionnaire, SDQ). RESULTS: Caregiver mental health was prospectively associated with all eight measures of child mental health at follow-up, adjusted for baseline. For post-traumatic stress, caregiver mental health had a predictive impact comparable to the child experiencing one or two lifetime trauma events. For depression, caregiver mental health approached the predictive impact of female gender. Thus a one SD change in caregiver SRQ-20 was associated with a 1.04 point change on CRIES and a 0.65 point change in DSRS. For multi-informant SDQ data, caregiver-child associations were strongest for caregiver ratings. For child-rated outcomes, associations were moderated by maternal literacy, a marker of family-level dynamics. Both adults and children identified domestic violence and quality of home life as independent risk and protective factors. CONCLUSIONS: In the context of violence and displacement, efforts to improve child mental health require a thoughtful consideration of the mental health cascade across generations and the cluster of adversities that impact family wellbeing. We identify culturally meaningful leverage points for building family-level resilience, relevant to the prevention and intervention agenda in global mental health. Language: en
Perinatal risk factors for neuroblastoma

Neuroblastoma is the most common cancer among infants, suggesting an etiologic role for prenatal factors. In this case-cohort study, neuroblastoma cases (n = 529) diagnosed between 1985 and 2001 were identified from the New York State Cancer Registry and were matched to the electronic birth records for 1983-2001 from New York State and New York City. Controls (n = 12,010) were selected from the same birth cohorts. Analysis was stratified by age at diagnosis, with one to six months (younger infants), seven to 18 months (older infants), and older than 18 months (older children) analyzed separately. Perinatal exposure data was obtained from the birth certificates. No risk factors were identified to be consistently associated with risk across all three age groups. Generally, more risk factors were identified as associated with neuroblastoma among younger infants relative to older ages, including high birth weight, heavier maternal gestational weight gain, maternal hypertension, older maternal age, ultrasound, and respiratory distress. Among older infants, low birth weight was associated with increased risk while heavier maternal gestational weight gain was protective. In the oldest age group, first born status, primary cesarean delivery, prolonged labor and premature rupture of the membranes were associated with increased risk.
Metallographic aspects of thick film technology

„Thick film technology” traces its ancestry to three sources: the preparation of decorative ceramic glazes, the fabrication of ceramic-to-metal seals, and the development of evaporated or sputtered “thin films” for electronic applications. Today, “thick films” are often the most reliable and also the cheapest route for satisfying numerous requirements in the functional packaging of semiconductor devices, and in related areas in microelectronics. The technology of thick film developments is heavily oriented toward problems related to multiphase structures and to interfaces. Typical thick films are essentially glass/metal composites, similar to the “cermets” which were so popular about a decade ago in attempts to develop structural materials for high temperatures. Micrographs and electron microprobe tracings will be shown to illustrate typical structures, and the defects occurring in them. Soldering, brazing, thermocompression bonding, ultrasonic bonding, eutectic die bonding, and several variations of these techniques are used for attaching devices and/or input-output connections to ceramic substrates via thick films. The interface problems associated with the sequential bonds generated in such processes are of great interest in the development of thick film compositions.
Optimizing the performance of a composite scintillation detector

The feasibility of creating a single, bulk detector from many smaller pieces of inorganic crystal scintillator was demonstrated in this research. The results show that light collection from multiple inorganic scintillators can be optimized via the properties of the non-scintillating medium, the packing factor of the crystals, and the cell geometry to yield a pulse-height spectrum of acceptable resolution. We were able to characterize changes in the 137 Cs gamma ray pulse height spectrum for increasing numbers of individual scintillators to the composite detector.
Synthesis and thermal isomerization of cis-3,4-diphenylcyclobutene

Abstract cis-3,4-Diphenylcyclobutene has been synthesized, and its thermal isomerization has been studied. Only the conrotatory product (> 99%), cis, trans-1,4-diphenylbuta-1,3-diene was observed; the rate constant is described by the Arrhenius equation: log k = 13·1–24·5/2·303 RT.
Reaction of peptide thiobenzyl esters with mammalian chymotrypsinlike enzymes: a sensitive assay method.

Abstract Sensitive methods for the determination of rat mast cell protease I, rat mast cell protease II, human skin chymotrypsinlike enzyme, dog skin chymotrypsinlike enzyme, human leukocyte cathepsin G, and bovine chymotrypsin A α with peptide thiobenzyl ester substrates are reported. Kinetic constants as well as the maximum sensitivity for the hydrolysis of the peptide substrates succinyl-phenylalanyl-leucyl-phenylalanine thiobenzyl ester and succinyl-alanyl-alanyl-prolyl-phenylalanine thiobenzyl ester were determined. Hydrolysis rates were followed spectrophotometrically at 324 nm by the formation of 4-thiopyridone (ϵ = 19,800 m −1 cm −1 ), the product of the reaction between benzylthiol, released during hydrolysis of the peptide thiobenzyl esters, and 4,4′-dithiodipyridine present in the assay mixture. Peptide thiobenzyl ester substrates were shown to be very sensitive substrates, predominantly because of the large extinction coefficient of 4-thiopyridone and the high k cat K m values for these compounds.
Data-efficient quickest change detection with unknown post-change distribution

The problem of quickest change detection is studied, where there is an additional constraint on the cost of observations used before the change point and where the post-change distribution is unknown. An algorithm is proposed for the case where there are finite number of possibilities for the unknown post-change distribution. It is shown that if the post-change family of distributions satisfies some additional conditions, then the proposed algorithm is asymptotically optimal uniformly for all possible post-change distributions.
Electron microscope studies on oocytes of an echinoderm, Thyone briareus, with special reference to the origin and structure of the annulate lamellae

Morphological variations observed in Thyone oocytes of different size indicate that cytoplasmic stacks of annulate lamellae have their origin as a result of the fusion of vesicular elements derived at least for the most part from a blebbing process of the outer layer of the nuclear envelope. Both the origin and growth of annulate lamellae appear capable of taking place in any region of the oocyte cytoplasm but appear to occur more often in the perinuclear region. Evidence was also obtained that the granular endoplasmic reticulum arises in this cell by a fusion of rough-surfaced vesicles; the process apparently being restricted to the region of the yolk nucleus and thus suggesting regional specificity in the ooplasm.
On the transport of the gulf stream between cape hatteras and the grand banks

Abstract Direct velocity observations from four locations in the Gulf Stream between Cape Hatteras and the Grand Banks are analysed to determine the baroclinic and barotropic transport of the Stream. Three of the sites are moored arrays where a method similar to that proposed by Hall and Bryden (1985, Geophysical Research Letters , 12 , 203–206) and Hall (1986, Journal of Physical Oceanography , 16 , 1814–1818) is used; the fourth is the Pegasus site of Halkin and Rossby (1985, Journal of Physical Oceanography , 15 , 1439–1452). The baroclinic transport is found to change little from site to site while the barotropic changes substantially. Total transport reaches 150 Sv at 60°W and remains at that strength to 55°W, the farthest east that moored information is available. These results, augmented by additional information, are used to deduce a scheme for the total transport steamfunction in the western North Atlantic.
Reentrant superconductivity from the anharmonic electron-phonon interaction

The Eliashberg equations are solved for the transition temperature of a superconductor for the case that the phonons are harmonic but the electron-phonon interaction is anharmonic. The anharmonic interaction increases the transition temperature for the same coupling strength. Reentrant behavior is predicted for large anharmonicity. {copyright} {ital 1997} {ital The American Physical Society}
Bartonella henselae endocarditis and glomerulonephritis with dominant C3 deposition in a 21-year-old male with a Melody transcatheter pulmonary valve: case report and review of the literature.

ABSTRACT We report a case of a 21-year-old young man with underlying congenital heart disease who developed Bartonella henselae endocarditis of the right ventricular outflow tract (RVOT) conduit of his Melody transcatheter (percutaneous) pulmonary valve (TPV), with an initial presentation of glomerulonephritis with a dominant C3 pattern, with renal failure and circulating cryoglobulins. There are few reports of a glomerulonephritis with a dominant C3 pattern presenting as a manifestation of B. henselae endocarditis. While most cases of B. henselae endocarditis affect the aortic valve, in this case the valve damage was to the RVOT of the Melody TPV, a percutaneous transcatheter valve delivery system that had previously replaced his pulmonary homograft, which had become dysfunctional as a result of prior Streptococcus viridans endocarditis. The pulmonary homograft had been in place since childhood as a result of a Ross procedure to repair his congenital aortic stenosis. The patient's renal failure significa...