cssi/SciSciGPT-SciSciNet huggingface dataset:
Program-wide implementation of the Pyramid Model: Supporting fidelity at the program and classroom levels

Abstract Many early childhood programs are not prepared to meet the needs of children who have significant social, emotional, and behavioral challenges. Program-Wide Supports for Pyramid Model Implementation (PWS-PMI) provides a systematic approach to supporting early childhood programs using Pyramid Model practices and enhancing children's social-emotional outcomes that is grounded in implementation science. We designed the current study to test the PWS-PMI intervention and examine its feasibility of implementation in community-based early childhood programs serving children from low-income environments. In this study, we found programs increased their implementation of PWS-PM and improved classroom practices after only one year of support. Our findings indicate a program-wide approach is effective, although more time and support will be necessary to sustain high fidelity implementation and produce robust effects on children.
Ordered macroporous materials by emulsion templating

Ordered macroporous materials with pore diameters comparable to optical wavelengths are predicted to have unique and highly useful optical properties such as photonic bandgaps1,2,3 and optical stop-bands4. Tight control over the pore size distribution might also lead to improved macroporous materials (those with pores greater than approximately 50 nm) for application as catalytic surfaces and supports5, adsorbents, chromatographic materials, filters6, light-weight structural materials7, and thermal, acoustic8 and electrical insulators9. Although methods exist for producing ordered porous materials with pore diameters less than 10 nm (refs 10, 11), there is no general method for producing such materials with uniform pore sizes at larger length scales. Here we report a new method for producing highly monodisperse macroporous materials with pore sizes ranging from 50 nm to several micrometres. Starting with an emulsion of equally sized droplets (produced through a repeated fractionation procedure12), we form macroporous materials of titania, silica and zirconia by using the emulsion droplets as templates around which material is deposited through a sol–gel process13. Subsequent drying and heat treatment yields solid materials with spherical pores left behind by the emulsion droplets. These pores are highly ordered, reflecting the self-assembly of the original monodisperse emulsion droplets into a nearly crystalline array14. We show that the pore size can be accurately controlled, and that the technique should be applicable to a wide variety of metal oxides and even organic polymer gels.
The Science Methods Course in the Context of the Total Teacher Education Experience

(1997). The Science Methods Course in the Context of the Total Teacher Education Experience. Journal of Science Teacher Education: Vol. 8, No. 4, pp. 269-282.
Representation and recognition of objects from depth maps

Object manipulation by a robot requires some degree of sensing, and of all possible forms of sensory perception, visual sensing is one of the most attractive because of its non-contact nature, high speed and accuracy. Visual data can be obtained in two or three-dimensional (depth map) form from commercially available sensors. Interpreting visual data has been one of the major themes of computer vision researchers in the past decade.In this paper, we present efficient techniques for object representation and recognition from dense range (depth) maps. The objects and models are represented by regions that are a collection of surface patches homogeneous in curvature-based surface properties. The recognition scheme is based on matching object surface descriptions with model surface descriptions. The recognition task includes both locating the overall object and identifying each of its features. Location is achieved by finding a geometrical “registration” function that correctly superimposes an arbitrary instance of the known model and the model. A localization technique is presented which requires that correspondence be established exactly, between one point on the object surface and one on the model surface. Once the single point correspondence is specified, closed form solutions are given for determining the attitude of the unknown view of the object in 3 space with respect to the model.
Dopamine Modulation of Responses Mediated by Excitatory Amino Acids in the Neostriatum

Publisher Summary This chapter summarizes several studies that have been designed to examine the electrophysiological interactions that occur when subtypes of dopamine (DA) and excitatory amino acid (EAA) receptors are activated simultaneously and to test the hypothesis that the direction of DA modulation is a function of both the subtype of EAA receptor and the subtype of DA receptor activated. The present findings demonstrate that the complex modulatory actions of DA are dependent on combinations of coactivation of specific subtypes of EAA and DA receptors. The chapter demonstrates that the direction of the modulatory effects of DA receptor agonists can be very predictable if the subtype of receptor activated is controlled. When N-methyl-D-aspartate (NMDA) receptors are activated, D1 DA receptor agonists potentiate excitatory responses. When non-NMDA receptors are activated, D2 DA receptor agonists attenuate excitatory responses. Application of the D2-receptor agonist, quinpirole produced inconsistent effects from cell to cell. Thus responses mediated by NMDA receptors are consistently potentiated by D1 DA agonists, while those mediated by non- NMDA receptors are consistently attenuated by D2 DA agonists. These findings are of clinical relevance since the actions of DA and EAAs have been implicated in neurological and affective disorders.
What happens when crops are turned on? Simulating constitutive volatiles for tritrophic pest suppression across an agricultural landscape

BACKGROUND Herbivore-induced plant volatiles, or HIPVs, are increasingly considered as a biocontrol enhancement tool by constitutively emitting these carnivore-attracting chemicals from agricultural fields. While ample data substantiate the olfactory preference of predators for HIPVs in laboratory environments, little is understood about the consequences of ‘turning crops on’ in the field. To explore the ramifications for arthropod pest management, a spatially explicit predator–prey population model was constructed that simulated a crop field releasing signals to recruit natural enemies from the surrounding landscape. RESULTS Field size had an overriding influence on model outcome, both isolated as a single factor and interactively shaping responses to other parameters (e.g. habituation, foraging efficiency). Predator recruitment exponentially declined with increasing field size from nearly double the baseline density in small fields (225 individuals m−2) to a mere 4% increase (130 individuals m−2) in large fields. Correspondingly, HIPVs enhanced pest consumption in small fields (ca 50% fewer prey), while generating virtually no impact in large fields. CONCLUSION Collectively, the model suggests that reducing the perimeter/core area ratio will ultimately constrain the utility of predator retention as a pest control tactic in commercial-sized fields and illustrates potential consequences of the widespread commercialization of this technology in agriculture. © 2014 Society of Chemical Industry
Relationship of initial hematocrit level to discharge destination and resource utilization after ischemic stroke: a pilot study.

Abstract Diamond PT, Gale SD, Evans BA. Relationship of initial hematocrit level to discharge destination and resource utilization after ischemic stroke: a pilot study. 2003:84:964–7. Objective: To examine the association between initial hematocrit level at the time of ischemic stroke, discharge destination, and resource utilization. Design: Case series. Setting: University hospital. Participants: A total of 1012 consecutive patients with ischemic stroke admitted to a university health system between August 3, 1995, and June 24, 1999. Interventions: Not applicable. Main Outcome Measures: Length of stay, hospital cost, and discharge disposition. Results: Of 1012 patients presenting with ischemic stroke, 58% were discharged home, 10% were discharged home with home care services, 15% were discharged to a rehabilitation hospital, 11% were discharged to a skilled or intermediate care facility, and 6% died. After adjusting for age, sex, race, and comorbidities, a significant association ( P =.009) existed between discharge outcome and initial hematocrit level. The probability of achieving an equivalent or less favorable outcome increased at both high and low hematocrit levels, with a minimum probability at a hematocrit level of approximately 45%. Conclusions: An association exists between hematocrit level at the time of ischemic stroke and discharge outcome. Midrange hematocrit levels appear to be associated with discharge to home rather than to an inpatient rehabilitation unit or to a nursing facility. Further study is indicated to examine the relationship among hematocrit level, stroke severity, and outcome.
Ultrastructure of Putrefactive Anaerobe 3679h During Sporulation

Sporulation of putrefactive anaerobe 3679h was studied by observation of ultra-thin sections in the electron microscope. The customary stages were observed during forespore formation, spore maturation, and liberation of the free spore. The exosporium was partially laminated and devoid of the hairlike surface projections observed on spores of some species. Atypical membrane configurations occurred in some cells, and, occasionally, cells with bipolar forespores were found.
Quantitative gas chromatography of 17-deoxycorti-costeroids and other steroids produced by the rat adrenal gland

Abstract A quantitative method has been developed for the determination of sub-microgram quantities of α-ketolic steroids and their immediate precursors. The method is particularly well adapted for the investigation of biosynthetic pathways in the rat adrenal cortex. Steroids isolated from rat adrenal incubates are treated with HIO 4 in aqueous dioxane to quantitatively convert α-ketolic steroids to the corresponding etiocholenic acids. Aldosterone and 18-hydroxydeoxycorticosterone form internal esters. Gas chromatographic analysis of the product prior to esterification determines progesterone, 11β-hydroxyprogesterone, 11β-hydroxyandrostenedione, 18-hydroxydeoxycorticosterone and aldosterone. Esterification of the same product with diazomethane yields volatile esters of the free etiocholenic acids in the mixture. Rechromatography then determines the previously mentioned compounds plus deoxycorticosterone, corticosterone and dehydrocorticosterone as methyl esters of the corresponding etiocholenic acids. Applications and limitations of this method of corticosteroid analysis are discussed.
An institutional theory of organizational communication

For many years, reviewers have argued that organizational communication research is overly concentrated on microphenomena to the neglect of macrophenomena, but macrophenomena have generally remained unspecified. An institutional theory of organizational communication is proposed to fill that gap. Drawing on institutional theory in organizational sociology and on concerns in organizational communication, we define institutions as constellations (i.e., relatively fixed arrangements) of formalized rational beliefs manifested in individuals’ organizing behaviors. Key concepts for the analysis of institutions include membership, rational myths, isomorphism, and decision hierarchies. Based on our definition and armed with these concepts, the paper formally specifies propositions of an institutional theory of organizational communication. Applying the propositions to a published case of organizational identification demonstrates how an institutional perspective offers additional explanatory power, especially concerning professional roles.
The Empire of Things: Regimes of Value and Material Culture

The Empire of Things: Regimes of Value and Material Culture. Fred R. Myers, ed. Santa Fe, NM: SAR Press, 2001. 366 pp.
Fabrication and preliminary testing of a planar membraneless microchannel fuel cell

Abstract A novel design for a planar membraneless microchannel fuel cell (PM2FC) as developed by -92-6, LLC is presented. The design, which eliminates the need for a polyelectrolyte membrane (PEM), takes advantage of the laminar flow of fuel and oxidant streams generated at a tapered flow boundary. This gives rise to a “virtual membrane” with diffusion at that interface being the only mode of mass transport between the two solutions. In addition, proton conduction occurs readily, and fuel crossover is virtually eliminated. Our planar design also gives rise to large contact areas between the electrodes and fuel and oxidant streams. As electrodes, we have employed platinum evaporated onto a polyamide film (Kapton®), allowing for the reproducible preparation of large-area electrode surfaces, which are also convenient for testing. Silicon microchannels, of varying width and height, have been tested and parameter optimization has been carried out using formic acid as fuel and oxygen as oxidant. Power densities on the order of 180 μW cm−2 have been obtained using this planar design. The open circuit potentials, as well as the kinetic behavior, observed for the formic acid fuel using this micro-fuel cell are compared to those of macro-fuel cell systems.
A shared memory parallel algorithm for data reduction using the singular value decomposition

This paper presents a parallel version of a singular value decomposition (SVD) based data reduction method for remotely sensed data that uses a training data set to find good basis vectors for the reduced dimension data. The parallel algorithm is implemented using Fortran 95, OpenMP, and LAPACK, and speedup results are given for up to 128 1.6 GHz processors of an SGI Altix 3700 with 512 MB of RAM. Performance is evaluated for various parallel options including scheduling strategies, data initialization, use of dplace, variable storage options, and cache optimization. Parallel speedup (without including time for input/output) using 128 processors reaches 75 with static scheduling and 190 with dynamic (guided) scheduling.
A Brief History of Statistics in Three and One-Half Chapters

(1991). A Brief History of Statistics in Three and One-Half Chapters. Historical Methods: A Journal of Quantitative and Interdisciplinary History: Vol. 24, No. 3, pp. 124-135.
Depression Among Chinese Americans: A Review of the Literature

The Chinese American population is among the fastest growing ethnic minority groups in the United States. Knowledge of the interaction between culture, disease expression, and utilization of psychiatric treatment by this population is limited. This article gives a general review of the literature on depression among Chinese Americans in order to clarify misconceptions, to increase knowledge of research on depression that has been done on one specific Asian-American group, and to set a direction for future nursing research and intervention.
Zeeman Tuning Rate for Q Branch Transitions in the v3 Band of NO2

Zeeman tuning rates have bee a measured for Q branch transitions in the v3 band of NO2(approx.1610/cm) for magnetic fields of up to 564 Gauss. The average measured tuning rate is 0.1815(53) x 10(exp -3)/cm/Gauss with no dependence on Ka within the approx. equal to 3% standard deviation. Despite significant ,pin-rotation interaction between several of the observed levels the result agrees with the simple linear model for Honda case (be molecules (tuning rate = 2muogs = 0.18696 x 10(exp -3)/cm/Gauss) which neglects the spin-rotation interaction between different J states. The Zeeman effect is analyzed in a full treatment of the Hamiltonian, including spin-rotation interaction, in order to account for the agreement with 2muogs and to explore the onset of spin-rotation effects in the spectra as the magnetic field is increased.
catena‐(Bis(μ2‐1,3‐bis(4‐pyridyl)­propane‐N,N′)‐di­aqua‐cobalt(II)) dinitrate 1,3‐bis(4‐pyridyl)­propane monohydrate

The hydro­thermally prepared title compound, [Co(C26H28N4)(H2O)2]2NO3·C13H14N2·H2O, (I), consists of infinite one-dimensional chains containing two independent Co2+ centers, each octahedrally coordinated by two water mol­ecules and four bridging 1,3-bis(4-pyridyl)­propane (bpp) ligands. The chains are linked into infinite two-dimensional layers by hydrogen bonding, via an uncoordinated bpp molecule, and further into a three-dimensional framework via interstitial nitrate anions and water mol­ecules. (I) is isostructural to the Ni analog previously reported [Krishnamohan Sharma et al., (2000). Cryst. Eng. 3, 201–208].
OVEREXPRESSION AND KINETIC CHARACTERIZATION OF THE CARBOXYLTRANSFERASE COMPONENT OF ACETYL-COA CARBOXYLASE

Acetyl-CoA carboxylase catalyzes the first committed step in the biosynthesis of fatty acids. TheEscherichia coli form of the enzyme consists of a biotin carboxylase protein, a biotin carboxyl carrier protein, and a carboxyltransferase protein. In this report the overexpression of the genes for the carboxyltransferase component is described. The steady-state kinetics of the recombinant carboxyltransferase are characterized in the reverse direction, in which malonyl-CoA reacts with biocytin to form acetyl-CoA and carboxybiocytin. The initial velocity patterns indicated that the kinetic mechanism is equilibrium-ordered with malonyl-CoA binding before biocytin and the binding of malonyl-CoA to carboxyltransferase at equilibrium. The biotin analogs, desthiobiotin and 2-imidazolidone, inhibited carboxyltransferase. Both analogs exhibited parabolic noncompetitive inhibition, which means that two molecules of inhibitor bind to the enzyme. The pH dependence for both the maximum velocity (V) and the (V/K)biocytinparameters decreased at low pH. A single ionizing group on the enzyme with a pK of 6.2 or lower in the (V/K)biocytin profile and 7.5 in theV profile must be unprotonated for catalysis. Carboxyltransferase was inactivated by N-ethylmaleimide, whereas malonyl-CoA protected against inactivation. This suggests that a thiol in or near the active site is needed for catalysis. The rate of inactivation of carboxyltransferase byN-ethylmaleimide decreased with decreasing pH and indicated that the pK of the sulfhydryl group had a pK value of 7.3. It is proposed that the thiolate ion of a cysteine acts as a catalytic base to remove the N1′ proton of biocytin.
Inhibition of premature ventricular extrastimuli by subthreshold conditioning stimuli

The purpose of this study was to determine whether trains of subthreshold high frequency conditioning stimuli (333 Hz, 1 ms duration, 2 ms interval) delivered to the canine ventricle inhibited the response to a premature stimulus (S2) more effectively than did a single subthreshold conditioning stimulus. It was found that trains of conditioning stimuli (mean 1.21 mA) inhibited the response to S2152 ms beyond expiration of the ventricular effective refractory period, whereas a single conditioning stimulus inhibited S2only 20 ms or less beyond the ventricular effective refractory period. In late diastole, trains of conditioning stimuli failed to inhibit S2when the train of stimuli caused ventricular depolarization or the latter occurred in response to the next sinus impulse. Trains of conditioning stimuli did not induce ventricular arrhythmias. Lidocaine or autonomic blockade did not alter the response to trains of conditioning stimuli. Trains of conditioning stimuli or a single conditioning stimulus inhibited the response to S2only when they were delivered at the same electrode site. By lengthening the ventricular effective refractory period, trains of conditioning stimuli could prevent or terminate tachycardias, but this possibility is constrained, at present, by the spatial limitations of the technique.
Preemption and the Obesity Epidemic: State and Local Menu Labeling Laws and the Nutrition Labeling and Education Act

Obesity is widely recognized as a preventable cause of death and disease. Reducing obesity among adults and children has become a national health goal in the United States. As one approach to the obesity epidemic, public health practitioners and others have asserted the need to provide consumers with information about the foods they eat. Some state and local governments across the United States have introduced menu labeling bills and regulations that require restaurants to post information, such as calorie content, for foods offered on their menus or menu boards. A major dilemma is whether state and local menu labeling laws are preempted by the federal Nutrition Labeling and Education Act (NLEA). While few courts have addressed this issue, ongoing litigation in New York City provides an early glimpse of judicial interpretation in this area. This article explores these preemption issues, arguing that appropriately written and implemented menu labeling laws should not be preempted by the NLEA. We offer guidance for states and localities that wish to develop and implement menu labeling laws.
Thermal analysis of poly(bisphenoxyphosphazene); single crystals and melt crystallized samples

High-molecular-weight polyphosphazenes are of considerable interest because of their potential use as relatively high temperature materials that also possess low glass temperature. A number of authors have examined the thermal properties of a wide range of polyphosphazenes. These studies, however, have usually been limited to compression-molded samples or to samples where the morphology or thermal history are poorly understood or highly complex. This article reports the thermal behavior of a single polymer, poly(bisphenoxyphosphazene) starting with the simplest morphological entity—the single crystal. The result of crystallization from the mesomorphic state [above T(1)] and from the melt were also examined, together with the influence of thermal cycling and heating rate. The effects of a variety of parameters on T(1) are reported. This work clearly demonstrates the importance of morphology–crystallization conditions in determining T(1) and suggests the presence of two crystal forms for this polymer.
The Discourse on Priesthood (Bl Add 18295, ff. 137b–140b): An Anti-Jewish text on the abrogation of the Israelite Priesthood

This previously unpublished Syriac text consists of two parts, a dialogue between a Jew and a Christian concerning the abrogation of the Israelite priesthood by that of Jesus Christ in heaven and a list of key points where the former and the latter priesthoods differ. Although his main source is the pseudo-Pauline Epistle to the Hebrews, the author of this text was influenced by Greek philosophical logic and may have written this text with the aim of debating with Jews.
The current and ideal state of mental health training: pediatric resident perspectives

Phenomenon: Mental health (MH) problems are prevalent in the pediatric population, and in a setting of limited resources, pediatricians need to provide MH care in the primary medical home yet are uncomfortable doing so citing a lack of training during residency as one barrier. Approach: The purpose of this study is to describe pediatric residents’ experiences and perspectives on the current and ideal states of MH training and ideas for curriculum development to bridge this gap. A qualitative study using focus groups of pediatric residents from an urban academic medical center was performed. Audio recordings were transcribed and analyzed using a grounded theory approach. Findings: Twenty-six residents participated in three focus groups, which is when thematic saturation was achieved. The team generated five major themes: capabilities, comfort, organizational capacity, coping, and education. Residents expressed uncertainty at every step of an MH visit. Internal barriers identified included low levels of com...
Calcium-sensitive cytosolic phospholipase A2 (cPLA2) is expressed in human brain astrocytes.

Abstract Calcium-sensitive cytosolic phospholipase A 2 (cPLA 2 ) is responsible for receptor-mediated liberation of arachidonic acid, and thus plays an important role in the initiation of the inflammatory lipid-mediator cascade generating eicosanoids and platelet-activating factor. In this study we have investigated the cellular distribution of cPLA 2 in brain using a monoclonal antibody raised against cPLA 2 to immunostatin tissue sections of human cerebral cortex. We have localized cPLA 2 in astrocytes of the gray matter. Colocalization with glial fibrillary acidic protein (GFAP) confirmed that cPLA 2 is associated predominantly with protoplasmic astrocytes. Astrocytes of the white matter, on the other hand, were not immunoreactive. In experiments using different human astrocytoma cell lines we found that cPLA 2 can be immunochemically localized in UC-11 MG cells, but cannot be detected in U-373 MG cells. This finding is consistent with the observation that cPLA 2 mRNA as well as cPLA 2 enzymatic activity can be readily measured in UC-11 MG astrocytoma cells, yet cannot be detected in U-373 MG cells. Our data suggest that the astrocyte is a primary source of cPLA 2 in the brain and provide further evidence for the importance of this cell type in inflammatory processes in the brain.
Management of pediatric ranula.

Objective: Many surgical techniques to manage ranulas have been described in the literature. These techniques include excision of the cyst with or without excision of the ipsilateral sublingual gland, marsupialization, cryosurgery, and CO2 laser excision. Few studies have described the approach toward management in pediatric patients. Methods: Six patients were treated for intraoral ranulas. Two patients had spontaneous resolution of their lesions. Four patients required dissection of the submandibular duct and lingual nerve to completely excise an oral cavity ranula and an ipsilateral sublingual gland. Results: There were no recurrent lesions. One patient developed a lingual nerve injury but no numbness. The 2 patients with spontaneous resolution did not develop a subsequent lesion. Conclusion: Optimal management of pediatric oral cavity ranulas may include observation for 5 months for spontaneous resolution. If the lesion does not resolve or recurs repeatedly, surgical treatment is recommended. Submandibular duct dissection with relocation appears to enhance exposure to the floor of mouth. The pseudocyst and entire sublingual gland should be removed. Identification of the lingual nerve is necessary to accomplish this goal. (Otolaryngol Head Neck Surg 2002;127:115-118.)
Temperature dependent intersystem crossing and triplet-triplet absorption of rubrene in solid solution

Abstract Relative fluorescence quantum yields and lifetimes of the first excited singlet state (S 1 ) of rubrene in sucrose octa-acetate glass have been measured as a function of temperature. From the thermal activation of intersystem crossing, it was found that the triplet state to which S 1 intersystem crosses lies 4600±400 cm -1 above S 1 . System dynamics were measured with picosecond pump-probe experiments as a function of temperature. The data yield the temperature dependent intersystem crossing rate constants and the triplet-triplet extinction coefficient, which was found to be 8800±600 L mol -1 cm -1 at 532 nm. The triplet-triplet extinction coefficient provides absolute calibration of the previously reported triplet-triplet absorption spectrum. Inclusion of stimulated emission quantitatively in the analysis of pump-probe experiments involving more than one pair of states is shown to be necessary for a proper analysis of system dynamics.
Spin-triplet pairing in large nuclei

The nuclear pairing condensate is expected to change character from spin singlet to spin triplet when the nucleus is very large and the neutron and proton numbers $Z,N$ are equal. We investigate the transition between these two phases within the framework of the Hartree-Fock-Bogoliubov equations, using a zero-range interaction to generate the pairing. We confirm that an extremely large nucleus would indeed favor triplet pairing condensates, with the Hamiltonian parameters taken from known systematics. The favored phase is found to depend on the specific orbitals at the Fermi energy. The smallest nuclei with a well-developed spin-triplet condensate are in the mass region $A~130--140$.
Studies on DNAase-Sensitive Antigens of Brucella abortus by Complement-Fixation.

SummaryComplement-fixation has proved to be a rapid, sensitive method of testing DNA preparations obtained from Brucella abortus for DNAase-sensitive antigens, and similarly, for analyzing antisera for possible antibodies against DNAase-sensitive antigens. Considerable variation in such antigens has been found among various DNA-rich preparations isolated from the same Brucella abortus strain and among antisera prepared against such preparations. The percentage of rabbits that yielded antibodies against DNAase-sensitive antigens following immunization with a preparation selected for DNAase-sensitive antigens was greater than that obtained in prior studies with unselected immunizing preparations.The efficient technical assistance of Miss Christine Pootjes, Mrs. Janet Collins, and Mrs. Janet Feder is gratefully acknowledged.
ULTRASONOGRAPHY AS AN AID IN THE DIAGNOSIS OF RENAL CELL CARCINOMA IN A HORSE

Clinical diagnosis of renal tumors in the horse has been difficult because the traditional diagnostic techniques are inadequate. Because of this shortcoming, early publications rarely reported antemortem diagnosis of primary renal tumors. Conventional radiographic techniques cannot effectively outline kidneys in the adult horse. With the advent of ultrasonography, a new dimension to the evaluation of the large-animal kidney has been introduced. Percutaneous diagnostic ultrasonography provides a noninvasive method of examining both kidneys. This report describes a 15 year-old Tennessee Walking Horse mare presented for evaluation of a mass in the sublumbar region, polyuria and polydipsia. Clinical examination and laboratory test results suggested intra-abdominal neoplasia. Two-dimensional ultrasonographic images of the mass were consistent with renal neoplasia. Histologic diagnosis of ultrasound-guided renal biopsy was renal tubular cell carcinoma.
Equilibrium states of nonlinearly elastic rods

Recently, several authors [l]-[7] have employed techniques of functional analysis to study the qualitative nature of solutions to nonlinear problems of elastic equilibrium. Of particular relevance to our investigation is the work of Tadjbakhsh and Odeh [6], w o h h ave treated the question of existence and bifurcation of solutions of an inextensible circular elastic ring subject to a hydrostatic pressure. The material of this ring is characterized by a constitutive relation of the Euler-Bernoulli type: The bending moment is a constant multiple of the change in curvature. In this paper we generalize and extend their work to prove existence theorems for the planar deformation under hydrostatic loads of both inextensible and extensible rods of arbitrary initial shape which are governed by constitutive laws of a hyperelastic type. This problem was treated from a different viewpoint in [8], where it was shown that if the initial shape of the rod is circular, then the solution can be expressed in closed form by quadratures from which qualitative features, such as periodicity, can be deduced.
Linear velocity fields in non-Gaussian models for large-scale structure

Linear velocity fields in two types of physically motivated non-Gaussian models are examined for large-scale structure: seed models, in which the density field is a convolution of a density profile with a distribution of points, and local non-Gaussian fields, derived from a local nonlinear transformation on a Gaussian field. The distribution of a single component of the velocity is derived for seed models with randomly distributed seeds, and these results are applied to the seeded hot dark matter model and the global texture model with cold dark matter. An expression for the distribution of a single component of the velocity in arbitrary local non-Gaussian models is given, and these results are applied to such fields with chi-squared and lognormal distributions. It is shown that all seed models with randomly distributed seeds and all local non-Guassian models have single-component velocity distributions with positive kurtosis.
Route of antigen administration for tolerance production

Abstract Tolerance production is readily induced by inoculation of heterologous serum proteins in mice. The intravenous and intraperitoneal route are generally preferred because they allow rapid antigen equilibrium in the intra and extravascular spaces of the host. This report shows that the administration of particle-free antigen in the foot pad produces a greater number of tolerant animals at all concentrations used. The active participation of regional lymph nodes in tolerance production is postulated.
The cooperative shift change: an illustration using air traffic control

We define the cooperative shift change and consider it from the perspective of four phases identified in Grusenmeyer (International Journal of Human Factors in Manufacturing, 5, 163–176, 1995): end-of-shift, arrival, meeting, and taking post. We describe the differences expected for the phases for both outgoing and incoming operators, discuss various domains that differ in their shift-change profile, and consider why those profile differences obtain. With this framework as a backdrop, we explore in detail the shift change, or position relief briefing (PRB), of air traffic control. This theoretical framework has the potential to aid in the classification and comparison of the transfer of responsibility in a variety of industrial tasks. This study could aid in the implementation of changes for air traffic control PRBs.
Electrographic tachyphylaxis to etomidate and ketamine used for refractory status epilepticus controlled with isoflurane.

Etomidate and ketamine controlled seizures but acute tachyphylaxis occurred. Isoflurane was then used to control seizures.
Synthesis and photoluminescence properties of hierarchical architectures of YBO3:Eu3+

We present a general hydrothermal method without any organic solvent or surfactant for the synthesis of YBO3:Eu3+ nano- and micro-structures. The samples were of excellent quality with uniform, well dispersed, self-assembled and self-purified YBO3:Eu3+. Single crystal nanoflakes gathered together to evolve into a hierarchical architecture with eight different types of three dimensional morphologies. Strong photoluminescence spectra were obtained at 592, 611 and 627 nm at excitations wavelengths 254 and 363 nm. The emission spectra are associated with the transitions from the excited 5D0 level to the 7FJ (J = 1, 2, 3, 4) levels of Eu3+ activators. YBO3:Eu3+ prepared using ethanol solvent exhibited the highest chromaticity values yet reported.
Distribution of membrane phospholipids in the rabbit neural retina, optic nerve head and optic nerve.

Abstract Since diseases of the neural retina and optic nerve can result in alteration of biological membranes, this study determines similarities and differences in the membrane phospholipid content of the neural retina, optic nerve head, and optic nerve to serve as baseline data. Neural retina, optic nerve head, and optic nerve were dissected, isolated as 5 sets from 20 rabbits and frozen in liquid N2. Separate pooled-tissue extracts were prepared for each set of tissues and phosphorus-31 nuclear magnetic resonance (31P NMR) analyses performed. Ten phospholipids were quantified (respective neural retina, optic nerve head, and optic nerve mole % are given for the 5 major phospholipids detected): phosphatidylcholine (PC), 44.61, 27.67, 26.40; PC plasmalogen or alkylacyl PC (CPLIP); phosphatidylinositol (PI); sphingomyelin (SM); phosphatidylserine (PS), 12.63, 14.77, 15.09; phosphatidylethanolamine (PE), 21.21, 9.59, 8.69; PE plasmalogen (EPLAS), 11.07, 30.96, 33.93; an unidentified (unknown) phospholipid (U) at the chemical-shift value of 0.13 ppm; diphosphatidylglycerol (DPG); and phosphatidic acid (PA), 0.46, 2.92, 1.57. Significant differences between the various tissues were determined by the one-way analysis of variance, using a Scheffe range value of P The neural retina in all phospholipids detected except for the uncharacterized (unknown) phospholipid was significantly different from the optic nerve head tissue. The optic nerve head was significantly different from the optic nerve in PC, CPLIP, PE, EPLAS, U, DPG, and PA. The data provide a baseline for studies on pathologically changed neural retina, optic nerve head, and optic nerve.
Comparative inhibition of hypothalamic uptake of 5-hydroxytryptamine and norepinephrine by 5-hydroxy- and 5-methoxy indole derivatives☆

Abstract 1. 1. Hypothalamic neuronal activity as measured by mechanisms of serotonin uptake, may be modified by various indole derivatives. 2. 2. 5-hydroxytryptophol and 6-methoxytetrahydroharman are competitive inhibitors of 5-HT uptake while 6-hydroxytetrahydroharman is a non-competitive inhibitor.
Eigenvalues of discontinuous Sturm-Liouville problems with symmetric potentials

Abstract In this paper we consider three examples of discontinuous Sturm-Liouville problems with symmetric potentials. The eigenvalues of the systems were determined using the classical fourth order Runge-Kutta method. These eigenvalues are used to reconstruct the potential function using an algorithm presented in Kobayashi [1, 2]. The results of our numerical experiments are discussed.
Mixing by low‐ and high‐resolution surface geostrophic currents

[1] The nature of mixing near the ocean's surface is investigated by considering passive tracer advection by currents derived geostrophically using sea surface height fields that differ in their spatiotemporal resolution. One is a low-resolution field that can be thought of as being derived using current-generation groundtrack altimetric measurements. The other is a high-resolution field that may be envisioned as derived using hypothetical next-generation wideswath altimetric measurements. The investigation is carried out in two world ocean regions with quite distinct characteristics and which have been the focus of recent studies on mixing by altimetry-derived currents. One region corresponds to an ample domain in the South Atlantic, which is traversed by vortices shed from the Agulhas current. The other region corresponds to a portion of the Pacific sector of the Southern Ocean, which is dominated by multiple zonal jets associated with the Antarctic Circumpolar Current. It is argued that while altimetry-derived currents capture the most salient characteristics of surface ocean mixing, deterministic Lagrangian calculations may be improved by considering surface geostrophic currents with greater spatiotemporal resolution. This is supported on analysis of probability distribution functions of finite-time Lyapunov exponents (FTLEs); inspection of Lagrangian coherent structures (or LCSs), which constitute distinguished material fluid curves that organize mixing; computation of kinetic energy and FTLE variance spectra; and realization of explicit passive tracer advection experiments.
Regional enteritis with pneumoperitoneum.

A 14-year-old male with previously undiagnosed regional enteritis presented with pneumoperitoneum. At surgery there was no identifiable perforation of the bowel and enteritis was confined to the upper jejunum. Reported cases of regional enteritis with pneumoperitoneum are reviewed and possible mechanisms discussed.
Sudden unexplained death caused by cardiac ryanodine receptor (RyR2) mutations.

© 2004 Mayo Foundation for Medical Education and Research See also page 1380 About 10% to 20% of postmortem examinations of young people who were apparently healthy but died suddenly and unexpectedly reveal no morphologic abnormalities to explain their deaths. In up to 50% of such cases, sudden unexplained death (SUD) is the first and only clinical manifestation. Recent studies have suggested that primary arrhythmogenic disorders such as congenital long QT syndrome, Brugada syndrome, idiopathic ventricular fibrillation, and catecholaminergic polymorphic ventricular tachycardia (CPVT) may underlie a substantial proportion of SUD cases. In all these arrhythmogenic cardiac disorders, there is no evidence of pathological abnormalities of the heart, and death would be classified as being of unknown etiology based on traditional postmortem examination. However, recent linkage of these syndromes to causative disease genes (mostly cardiac ion channels) has provided the opportunity to elucidate a pathogenic basis for SUD. In the current issue of the Mayo Clinic Proceedings, Tester et al elegantly demonstrate, using molecular genetic analysis, that mutations in the cardiac ryanodine receptor gene (RyR2) may be associated with about 14% of SUD cases. Mutations in RyR2 have previously been linked to CPVT and arrhythmogenic right ventricular dysplasia type 2 (ARVD2) (Table 1). Moreover, mutations in the calsequestrin gene (CASQ2) have been linked to an autosomal recessive form of CPVT. Unlike ARVD2, which is associated with progressive degeneration of the right ventricular myocardium, CPVT is not characterized by structural heart disease. Although CPVT is characterized by normal electrocardiographic patterns at rest, it is arguably one of the most malignant types of inherited cardiac arrhythmia syndromes. Exercise or sympathetic nervous system activation induces ventricular arrhythmias, syncope, or sudden cardiac death in most patients with CPVT, leading to mortality rates of 30% to 50% at age 35 years. The findings by Tester et al also suggest the involvement of catecholamines in the onset of lethal arrhythmias—of 7 patients, 3 died during exertion, and 1 died during potential emotional stress. Clinical electrophysiologic studies of patients with RyR2 Sudden Unexplained Death Caused by Cardiac Ryanodine Receptor (RyR2) Mutations
Foundations of multi-paradigm modeling and simulation: a port ontology for automated model composition

We study the cooncept of ports and we define an ontology for representing them. Ports define the locations of interaction at the boundaries of components or sub-systems; they can be used across different disciplines for both product moodeling and simulation. They are therefore a coonvenient abstraction that allows simulation modelers too moodularize and encapsulate their system descriptions such that configurations oof port-based prooduct models can be used to generate multiple simulation moodels at different levels of abstraction. However, to combine system models effectively across different disciplines, the representation of the ports needs to be unambiguous yet flexible, so that it can accommodate the differences in vocabulary and approach of all the disciplines. We provide an overview of how a port ontology, defined in the web ontology language, OWL, can capture both syntactic information such that autoomated modelers can reason about the system configuratioon and corresponding simulation models.
Feasibility and Benefit of Parent Participation in a Program Emphasizing Preschool Child Language Development While Homeless

Purpose This exploratory study examined the feasibility of homeless parents' participation in an intervention to increase use of facilitating language strategies during interactions with their pres...
Collision and Coalescence of Water Drops

Abstract The coalescence efficiency of drops of diameter 0.5≤d≤2.5 mm colliding in an electric field of 70 V cm−1 was found to be about 0.5. The interactions were observed in the test section of a vertical wind tunnel; for events which were not head-on (small impact parameters) collisions, the coalescence efficiency was found to decrease with increasing impact velocity.
Effectiveness of a Smartphone Application for Weight Loss Compared With Usual Care in Overweight Primary Care Patients: A Randomized, Controlled Trial

Background: Many smartphone applications (apps) for weight loss are available, but little is known about their effectiveness. Objective: To evaluate the effect of introducing primary care patients ...
ENDOR spectroscopic evidence for the geometry of binding of retro-inverso-N(ω)-nitroarginine-containing dipeptide amides to neuronal nitric oxide synthase

We describe in detail the use of 35 GHz Mims pulsed 15N and 1,2H electron−nuclear double resonance (ENDOR) spectroscopy to study the binding of substrates and inhibitors to nitric oxide synthase (N...
Simulation of particle collection by model fiber filters

Abstract Computer simulations of particle deposition in model fiber filters were conducted. The basic element of the model filters used in the simulation consisted of three identical parallel and equally spaced circular cylinders, with the flow field around the cylinder obtained using the method of Lehner. The deposition process was simulated using the method developed earlier by the present author. The procedure was further modified by including an adhesion mechanism. Both monodispersed and polydispersed aerosols were considered. The results of the simulation agreed with the available experimental data.
High-resolution satellite and airborne thermal infrared imaging of precursory unrest and 2009 eruption at Redoubt Volcano, Alaska

Abstract A combination of satellite and airborne high-resolution visible and thermal infrared (TIR) image data detected and measured changes at Redoubt Volcano during the 2008–2009 unrest and eruption. The TIR sensors detected persistent elevated temperatures at summit ice-melt holes as seismicity and gas emissions increased in late 2008 to March 2009. A phreatic explosion on 15 March was followed by more than 19 magmatic explosive events from 23 March to 4 April that produced high-altitude ash clouds and large lahars. Two (or three) lava domes extruded and were destroyed between 23 March and 4 April. After 4 April, the eruption extruded a large lava dome that continued to grow until at least early July 2009.
Prevention of Resistant CMV Infection Using Persistent Valganciclovir Therapy through Leukopenia and Extending the Duration

Purpose Cytomegalovirus (CMV) infection increases morbidity and mortality in lung transplant recipients. Our center identified CMV-resistant (rCMV) disease resulting in the death of 3 out of 4 cases. We attributed rCMV to erratic dosing, inconsistent medication levels, and a shortened duration of valganciclovir (Val) prophylaxis. We describe the effect of changes in a prophylaxis protocol in order to prevent rCMV in at-risk patients. Methods and Materials The Pre-intervention cohort (Pre 3/08-4/11) received prophylaxis with Val for 3 (D+ and D-/R+) to 6 (D+/R-) months; Val was held for WBC 6 months and followed ≥12 months were included. Frequency of CMV events, time to first event (unadjusted and adjusted for changes in Val or IS), frequency of changes in Val dosing or IS (due to adverse effects) and frequency of rCMV were compared. Results 54 Pre and 23 Post patients were included. CMV event frequency (Pre 23/54 (43%) vs. Post 9/23 (39%) (p=0.77)), median time to events (Pre 54 days, Post 69 days) and time to event analysis was not different between groups (HR 1.087, 95% CI 0.50-2.35). Changes in IS or Val dosing were not more frequent Pre (11/54 (20%)) versus Post (6/23 (26%)) (p=0.57). Pre was associated with development of rCMV in 4/54 (7%) patients, but rCMV in Post has not yet been detected. Conclusions Our combination therapy was successful in preventing rCMV in at-risk patients even though the frequency of CMV events and the changes in IS or Val dosing were unchanged. Our findings suggest that a longer duration of prophylaxis with consistent dosing and perhaps the addition of CMV-IVIg leads to a reduction in rCMV.