cssi/SciSciGPT-SciSciNet huggingface dataset:
Abstract 1591: Protein kinase Cε, which is linked to ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas, associates with Hsp90β, a core component of multiprotein complex inolving several collaborating chaperones Hsp70/Hsp40, Hop/sti, Cdc37 and p21

Chronic exposure to ultraviolet radiation (UVR) is the most common etiologic factor linked to the development of squamous cell carcinoma (SCC), a nonmelanoma form of skin cancer that can metastasize. We have reported that protein kinase C epsilon (PKCe) expression level dictates the susceptibility of mice to the development of SCC by UVR. As compared to wildtype littermates, PKCe over-expressing transgenic mice exhibit decreases in tumor latency by 12 weeks and a 3-fold increase in tumor multiplicity (Cancer Research, 64, 7756, 2004). To find clues about the mechanism by which PKCe may impart susceptibility to UVR-induced development of SCC, we found that PKCe interacts with heat shock protein (Hsp) 90β. Hsp90 is a ubiquitous molecular chaperone, which plays key roles in the folding, activation and assembly of a range of structurally and functionally different client proteins (e.g., telomerase, nuclear hormone receptors, protein kinases) in eukaryotic cells. Hsp90, a core component of multiprotein complex involving several collaborating chaperons (e.g., Hsp70/Hsp40, Hop/sti1, Cdc37, p21), exhibits a high degree of specificity towards client proteins. In the present experiments, mice were exposed to a single UVR (2 kJ/m2) treatment, emitted by Kodacel-filtered FS-40 sun lamps (approximately 60% UVB and 40% UVA). In reciprocal immunoprecipitation/blotting experiments, Hsp90β and its associated chaperons Hsp70 and p21 co-immunoprecipitated with PKCe in intact mouse epidermis in vivo. The association of PKCe with Hsp90β was further enhanced after UVR exposure of dorsal skin in both PKCe transgenic and wild-type mice. The association of PKCe with Hsp90β was significantly increased in PKCe over-expressing transgenic mice as compared to wild-type littermates. In summary, association of Hsp90 with its client PKC is essential for both its maturation into a signaling-competent enzyme and enzyme stability (JBC, 284: 4921, 2008). In UVR mouse skin carcinogenesis, association of Hsp90β with PKCe may be required for sustained PKCe activity. We have previously reported that PKCe interacts with Stat3, phosphorylates Stat3Ser727 and is essential for Stat3-regulated gene expression (Cancer Research, 67, 1385, 2007). PKCe overexpressing transgenic mice exhibits constitutive activation of Stat3 and increased susceptibility to SCC induction by UVR. Association of Hsp90 with PKCe may critical for these biological effects. We conclude that Hsp90, PKCe and Stat3 are potential molecular targets for human cancer prevention and treatment (Support: NIH grants CA102431, CA35368 and T32ES007015) Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 1591.
Transmission network-based energy and environmental assessment of plug-in hybrid electric vehicles

The introduction of plug-in hybrid electric vehicles (PHEVs) is expected to have a significant impact on regional power systems and pollutant emissions. This paper analyzes the effects of various penetrations of PHEVs on the marginal fuel dispatch of coal, natural gas and oil, and on pollutant emissions of CO2, NOx, SO2 in the New York Metropolitan Area for two battery charging scenarios in a typical summer and winter day. A model of the AC transmission network of the Northeast Power Coordinating Council (NPCC) region with 693 generators is used to realistically incorporate network constraints into an economic dispatch model. A data-based transportation model of approximately 1 million commuters in NYMA is used to determine battery charging pattern. Results show that for all penetrations of PHEVs network-constrained economic dispatch of generation is significantly more realistic than unconstrained cases. Coal, natural gas and oil units are on the margin in the winter, and only natural gas and oil units are on the margin in the summer. Hourly changes in emissions from transportation and power production are dominated by vehicular activity with significant overall emissions reductions for CO2 and NOx, and a slight increase for SO2. Nighttime regulated charging produces less overall emissions than unregulated charging from when vehicles arrive home for the summer and vice versa for the winter. As PHEVs are poised to link the power and transportation sectors, data-based models combining network constraints and economic dispatch have been shown to improve understanding and facilitate control of this link.
Childhood Giftedness and Adulthood Genius: A Historiometric Analysis of 291 Eminent African Americans

Although the association between giftedness and genius has been the subject of several retrospective, longitudinal, and historiometric studies, this research concentrated on majority-culture samples. In the current study, Cox's (1926) findings regarding 301 geniuses were replicated on a sample of 291 eminent African Americans. Relative genius was measured by two archival eminence measures (majority White and minority Black culture) and by scores on the Creative Achievement Scale (Ludwig, 1992). Giftedness was assessed by raters blind to the identity of the individuals being evaluated. Control variables were defined for gender, year of birth, status as a living contemporary, and 18 domains of achievement. Multiple regression analyses indicated that adulthood eminence and creative achievement are positively correlated with early giftedness, with an effect size comparable to that found in the Cox study. Furthermore, this association was not moderated by gender, birth year, or most of the remaining variables
Thulium sensitized neodymium for mid-IR laser development

The energy transfer properties between Tm/sup 3+/ and Nd/sup 3+/ in KPb/sub 2/Cl/sub 5/ are explored. The efficiency of the energy transfer from the Tm /sup 3/H/sub 4/ to the Nd/sup 4/I/sub 11/2/was evaluated for sensitization of a new mid-IR laser system.
Destination Clustering Geographic Multicast forWireless Sensor Networks

Geographic routing has been proven to provide efficient and scalable unicast routing in resource-constrained sensor networks. However, its applications in multicast routing remain largely unexplored. In this paper, we propose the DCGM (destination clustering geographic multicast) routing protocol for wireless sensor networks. By clustering destinations that can share the same next hop, we iteratively select the next hop as the neighbor with the maximum number of destinations. We prove that the complexity of DCGM is O(nk), where n is the number of neighbors of the current node and k is the number of destinations associated with the current node. Simulations show that DCGM achieves better performance than existing geographic multicast algorithms in terms of path length, but with much lower computation complexity.
A wavelet-based Fock space: a new multi-scale space for nonlinear dynamical systems

Generalized Fock (GF) spaces were introduced by de Figueiredo and associates in late 1970's and early 1980's for generic representation of the input-output maps of nonlinear dynamical systems. Since then the underlying concepts and methods have been used and further developed by the present authors and others in the context of a number of applications including neural networks (see, e.g., the paper by de Figueiredo in the invited session on Fundamental of Neural Networks in this ISCAS'96 Proceedings). A GF Space F consists of sequences of tensor products of a given Hilbert space H. When H is L/sub 2/(R), the elements of F are Volterra series. In the present paper we introduce a GF space F whose elements are constructed from an L/sub 2/(R) equipped with an orthonormal wavelet basis. This provides a unique setting for modeling identification and control of nonlinear dynamical systems at multiple scales as elicited by the underlying wavelet basis.
Household Saving, Class Identity, and Conspicuous Consumption

The saving rate for U.S. households has long been low relative to those in other wealthy countries and in recent decades this rate has plummeted. Most studies of household saving behavior are based...
A 4.78 mm 2 Fully-Integrated Neuromodulation SoC Combining 64 Acquisition Channels With Digital Compression and Simultaneous Dual Stimulation

A 65 nm CMOS 4.78 mm 2 integrated neuromodulation SoC consumes 348 µA from an unregulated 1.2 V to 1.8 V supply while operating 64 acquisition channels with epoch compression at an average firing rate of 50 Hz and engaging two stimulators with a pulse width of 250 µs/phase, differential current of 150 µA, and a pulse frequency of 100 Hz. Compared to the state of the art, this represents the lowest area and power for the highest integration complexity achieved to date.
Measurement of the microwave conductivity of a polymeric material with potential applications in absorbers and shielding

The microwave conductivity of a new material, the polymer poly-p-phenylene-benzobis-thiazole (PBT) made conductive by ion-implantation doping with iodine, is measured at 9.89 GHz as a function of temperature using the cavity perturbation technique applicable to thin films of arbitrary shape. The DC and microwave conductivities of PBT are seen to approach asymptotically the low-temperature limit predicted by Mott's energy-dependent hopping model. The potential utilization of conductive polymers in microwave absorbers and electromagnetic interference (EMI) shielding is examined using layered media EM theory. >
Is news sharing on Twitter ideologically biased

In this paper we explore effects of perceived ideology of news outlets on consumption and sharing of news in Twitter. Selective exposure theory suggests that when given access to a broad range of information, people will tend to consume and share news that confirms their existing beliefs and biases. We find that users share news in similar ways regardless of outlet or perceived ideology of outlet, and that as a user shares more news content, they tend to quickly include outlets with opposing viewpoints. This suggests that while perceived ideology does not inspire most Twitter users to treat liberal or conservative news outlets differently, it is a factor in their news consumption and sharing. Specifically, users in our sample who sent multiple tweets tended to increase the ideological diversity in news they shared within two or three tweets, and users' information diversity increased as their number of tweets sent increased.
Organizational Perspectives for Public Relations Research and Practice

In this article, the authors review three broad paradigms from organizational research—functionalist, interpretive, and critical—and some of the representative theoretical approaches within each of these paradigms. They discuss the implications of these various perspectives for research in public relations and illustrate these implications with examples of research from public relations literature. They conclude with a brief analysis of the public relations efforts of Johnson and Johnson during the Tylenol crisis and illustrate how organizational theory and research can inform our analyses of public relations research and practice.
Plasma and cerebrospinal fluid (CSF) pharmacokinetics of CP‐457,920, a selective alpha 5 GABA‐A receptor inverse agonist in young, healthy volunteers

Background CP-457,920 is a selective α5 GABAA receptor inverse agonist studied for the treatment of dementia in Alzheimer's Disease. In vitro, the compound has a potent Ki of ~ 1 ng/mL for the α5 GABAA receptor and is a substrate for efflux transporters. However, preclinical microdialysis studies in rats have shown an extracellular fluid (ECF) to CSF ratio that approaches unity. Objectives To estimate CNS penetration of CP-457,920 after multiple oral dose administration to healthy young adult subjects as measured by the CSF concentration and the CSF to unbound plasma concentration ratio at steady-state. Methods CP-457,920 was administered 120 mg BID for 4 days to 6 young healthy volunteers. On day 4 plasma was collected at just prior to dosing and at 1, 2, 3, 4, 6, 8 and 12 hours after dosing. A CSF sample was collected at approximately 4 hours post dose. Results CP-457,920 was quantifiable in the CSF of all 6 subjects at 4 hours post dose. The CP-457,920 CSF/unbound concentration ratio was on average approximately 6-fold less than unity. Despite this disequilibrium, approximately 75% receptor occupancy would be projected at Cmax in healthy volunteers. Conclusions At steady-state, CP-457,920 CSF penetration was observed at concentrations greater than the in vitro receptor Ki. The CSF/unbound plasma disequilibrium may be due to low permeability and/or P-gp mediated efflux. Clinical Pharmacology & Therapeutics (2004) 75, P30–P30; doi: 10.1016/j.clpt.2003.11.115
TLR4 Signaling via MyD88 and TRIF Differentially Shape the CD4+ T Cell Response to Porphyromonas gingivalis Hemagglutinin B

Recombinant hemagglutinin B (rHagB), a virulence factor of the periodontal pathogen Porphyromonas gingivalis, has been shown to induce protective immunity against bacterial infection. Furthermore, we have demonstrated that rHagB is a TLR4 agonist for dendritic cells. However, it is not known how rHagB dendritic cell stimulation affects the activation and differentiation of T cells. Therefore, we undertook the present study to examine the role of TLR4 signaling in shaping the CD4+ T cell response following immunization of mice with rHagB. Immunization with this Ag resulted in the induction of specific CD4+ T cells and Ab responses. In TLR4−/− and MyD88−/− but not Toll/IL-1R domain-containing adapter inducing IFN-β–deficient (TRIFLps2) mice, there was an increase in the Th2 CD4+ T cell subset, a decrease in the Th1 subset, and higher serum IgG1/IgG2 levels of HagB-specific Abs compared with those in wild-type mice. These finding were accompanied by increased GATA-3 and Foxp3 expression and a decrease in the activation of CD4+ T cells isolated from TLR4−/− and MyD88−/− mice. Interestingly, TLR4−/− CD4+ T cells showed an increase in IL-2/STAT5 signaling. Whereas TRIF deficiency had minimal effects on the CD4+ T cell response, it resulted in increased IFN-γ and IL-17 production by memory CD4+ T cells. To our knowledge, these results demonstrate for the first time that TLR4 signaling, via the downstream MyD88 and TRIF molecules, exerts a differential regulation on the CD4+ T cell response to HagB Ag. The gained insight from the present work will aid in designing better therapeutic strategies against P. gingivalis infection.
Separation of Powers and the Politics of Administrative Rule Review

In many states, agency rules are subject to review and possible veto by elected political officials in the legislative and/or executive branches. The consequences of this rule review authority are ...
Instructional Theory and Technology for the New Paradigm of Education

This article describes instructional theory that supports post-industrial education and training systems – ones that are customized and learner-centered, in which student progress is based on learning rather than time. The article describes universal methods of instruction, situational methods, core ideas of the post-industrial paradigm of instruction, the importance of and problems with task-based instruction, a vision of an instructional theory for post-industrial education and training, and the roles that may be played by the teacher, the learner, and technology in the new paradigm.
Evasion of Innate Immune Responses: Evidence for Mannose Binding Lectin Inhibition of Tumor Necrosis Factor Alpha Production by Macrophages in Response to Blastomyces dermatitidis

Serum factors, including mannose binding lectins (MBL), influence innate responses to microbes. Little is known about the effects of serum factors or MBL on the interaction of Blastomyces dermatitidis, a pulmonary fungal pathogen, with macrophages or on tumor necrosis factor alpha (TNF-alpha) production. Since macrophage production of TNF-alpha is an important innate immune response, we examined a mouse peritoneal macrophage (PM) cell line (RAW) and resident PM from CD-1 mice to study TNF-alpha production by PM stimulated with heat-killed (HK) or live B. dermatitidis yeast cells. Mouse serum and heat-inactivated mouse serum inhibited TNF-alpha production 94% when macrophages were stimulated by B. dermatitidis, whereas mouse immunoglobulin G (IgG) did not have this effect. HK B. dermatitidis incubated with serum and then washed also failed to stimulate significant TNF-alpha production by PM. By the sandwich immunofluorescent antibody (IFA) method with anti-mouse MBL (MBL-A or -C), we showed that serum MBL bound to B. dermatitidis. When serum was absorbed with HK B. dermatitidis or live B. dermatitidis, absorbed serum failed to significantly inhibit TNF-alpha production by RAW cells plus B. dermatitidis, and immunoblotting showed that absorbed serum was depleted of MBL-C. If serum was absorbed with live B. dermatitidis, unbound serum was eluted, and bound serum factor(s) (BS) was released with guanidine buffer, BS inhibited TNF-alpha production by PM plus B. dermatitidis in a concentration-dependent manner. BS contained MBL-C, which bound B. dermatitidis, as shown by IFA assay. 1,3-beta-Glucan stimulated TNF-alpha production by PM, and this was inhibited by mouse serum. Treatment of B. dermatitidis with anti-1,3-beta-glucan antibody inhibited TNF-alpha production by PM. With anti-1,3-beta-glucan antibody, we showed by IFA assay that B. dermatitidis contained 1,3-beta-glucan. In an IFA study with B. dermatitidis, serum with an anti-mouse IgG conjugate did not result in fluorescence, yet serum blocked IFA staining of B. dermatitidis by anti-1,3-beta-glucan IgG antibody. This indicated that non-IgG serum factors binding to B. dermatitidis prevented access to 1,3-beta-glucan by anti-1,3-beta-glucan antibody. These results suggest that the mechanism of inhibition of the innate proinflammatory immune response of PM to B. dermatitidis is mediated by serum MBL binding to B. dermatitidis at 1,3-beta-glucan sites or sterically masking 1,3-beta-glucan sites, thus preventing 1,3-beta-glucan stimulation of PM for TNF-alpha production.
On the stability of saturating nonlinear feedback systems

A saturating nonlinearity contained in a stable feedback system can be considered to lie within the sector [ \varepsilon,k ]. Thus all the well-known Popov-type stability criteria are applicable for the saturating nonlinear feedback system.
Optimal twist vectors as a tool for interpolating a network of curves with a minimum energy surface

Abstract This paper provides a new answer to the old problem of specifying the mixed partial derivatives (MPDs) or ‘twist vectors’ at the grid points for an interpolating surface over a rectangular network of curves. An algorithm is presented for finding the MPDs that minimizes a generalized energy integral over the entire surface. The integrand may be any quadratic form in the second partial derivatives of the surface. This results in a surface design technique for interpolating over a network of curves by automatically selecting the optimal twist vectors at the grid points.
Graft survival and promotion of female and male strobili by topgrafting in a third-cycle slash pine (Pinus elliottii var. elliottii) breeding program

A total of 2561 slash pine (Pinus elliottii Engelm. var. elliottii) grafts were topgrafted in the winter of 2003 and evaluated in January of 2004. The objectives of this study were to understand the effect of the genetic material and crown position on survival and flowering response of topgrafts. Also, the effects of geographic direction, branch order, and scion age on topgraft response were assessed. Topgrafting was an effective tool for promoting both female and male strobili. The genetic material (scion and interstock clones) and the crown position had large effects on the promotion of female flowering and topgraft survival. More than 23% of the total variation in female flowering and 16.3% of the total variation in topgraft survival were due to differences among scion clones and among interstock clones, respectively. The highest survival rate was reached by grafting in the mid-top followed by the top crown position. Grafting in the top of the crown was highly superior in promoting female strobili foll...
PERITONEOVAGINAL FISTULA-UNUSUAL COMPLICATION OF PERITONEAL DIALYSIS

The formation of a peritoneovaginal fistula was observed in a young female who had undergone continuous peritoneal dialysis for 17 months. The patient had experienced an episode of acute bacterial ...
The efficacy of simulation debriefing in developing critical thinking in accelerated baccalaureate nursing students

Background: Critical thinking is an essential attribute of a nurse. Nursing education which incorporates simulation and debriefing learning activities has an important role to ensure key components of safety and clinical effectiveness are present before nursing students graduate. Aims and methods: To examine, using Quality and Safety Education for Nurses (QSEN) based rubrics, the relationship between simulation debriefing and critical thinking in nursing students enrolled in an accelerated second degree baccalaureate program. Results: Univariate Spearman Rho regression showed a significant direct relationship between critical thinking and all five components of debriefing (allowing reflection on student’s clinical judgement and approach to patient care; feedback received supportive and constructive; feedback helpful to learning; adequate time given to reflect and discuss clinical performance; and helping understand the rational for the actions and responses to performances). Logistic multivariate regression revealed that only three out of the five debriefing components predicted developing stronger critical thinking skills: allowing reflection on student’s clinical judgement and approach to patient care (χ 2 = 34.249, p = .011), adequate time given to reflect and discuss clinical performance (χ 2 = .068, p = .030), and helping understand the rational for the actions and responses to performances (χ 2 = 119.365, p = .001). Conclusions: Debriefing is an important aspect of simulation which helps enhance critical thinking skills in nursing students and thus should be appropriately addressed in education and research.
Shore Line Effects on Mixing of a Tee Diffuser

Submerged multi-port diffusers are often used to discharge waste heat resulting from once-through cooling at coastal power plants. For shallow receiving waters characterized by weak ambient currents (e.g., large lakes), a tee diffuser, with diffuser axis parallel to shore and ports oriented offshore, provides the most effective mixing. However, if the diffuser is sufficiently close to shore, dilution is reduced because of the limited availability of ambient dilution water reaching ports from behind the diffuser. A semi-empirical theory, with laboratory calibration, accounts for the reduced dilution for a tee diffuser in shallow, quiescent water of constant depth near a parallel shoreline. Dilution is reduced by 10% when the ratio of distance offshore to diffuser length is about 0.8 while dilution drops by 30% when the raio is about 0.35. For a sloping bottom, similar results are expected if the distance offshore is taken as one-half of the actual distance.
Wireless Sensor Networks with RF Energy Harvesting: Energy Models and Analysis

This paper formulates the location-dependent power harvesting rates in generalized 2D and 3D placement of multiple Radio Frequency (RF) Energy Transmitters (ETs) for recharging the nodes of a wireless sensor network (WSN). In particular, we study the distributions of total available and harvested power over the entire WSN. We provide closed matrix forms of harvestable power at any given point in space due to the action of concurrent energy transfer from multiple ETs, explicitly considering constructive and destructive interference of the transmitted energy signals. We also analyze the performance of energy transfer in the WSN through power outage probability, interference, and harvested voltage as a function of the wireless power received from the ETs. Our results reveal that the network wide received power and interference power from concurrent energy transfers exhibit Log-Normal distributions, and the harvested voltage over the network follows a Rayleigh distribution.
Theory Driven Community Analytics and Influence on Community Success

This paper describes two projects that analyze online community behaviors. The first discusses the modeling of emotional and factual language within argumentative forums. When applied to enterprise communities, this model is found to be a predictor of member satisfaction. The next project covers a unique perspective of member and owner content creation and curation behaviors across the lifecycle of online communities. Both members and owners are found to increase in content posting but the level of linking is role dependent.
Association between prediabetes and risk of chronic kidney disease: a systematic review and meta-analysis

Abstract To assess the effect of prediabetes (impaired fasting glucose and/or impaired glucose tolerance) on the incidence of chronic kidney disease. PubMed and EMBASE were searched (for studies published up to March 2015). Effects estimated from cohort studies reporting the relationship of prediabetes to incident chronic kidney disease [kidney damage (microalbuminuria, albuminuria or proteinuria) and/or decreased glomerular filtration rate] were pooled using a random-effects model meta-analysis. Nine cohort studies with a total of 185 452, mainly Asian and white, participants were followed for a total of 835 146 person-years. In eight cohort studies defining impaired fasting glucose as fasting glucose 6.1-6.9 mmol/l, the summary relative risk of chronic kidney disease after adjustment for established risk factors was 1.11 (95% CI 1.02-1.21). When a study defining impaired fasting glucose as fasting glucose 5.6-6.9 mmol/dl was added, the overall relative risk of chronic kidney disease was 1.12 (95% CI 1.02-1.21). Exclusion of the only study with information on impaired glucose tolerance did not change the relative risk (1.12; 95% CI 1.02-1.21). There was no evidence of publication bias (P value for Egger test = 0.12). Prediabetes is modestly associated with an increase in chronic kidney disease risk, but this remains to be robustly confirmed. Chronic kidney disease screening among people with prediabetes, and aggressive management of prediabetes in those with chronic kidney disease may be warranted. This article is protected by copyright. All rights reserved.
EARLY ACCOUNTS OF FUNGAL BIOLUMINESCENCE

According to Harvey (1957), written observations and speculations on the nature of fungal bioluminescence can be traced as far back as Aristotle. Among the important discoveries Harvey cites are Bacon's observations (1677) on the essential similarity of the luminescence of wood and other objects, Boyle's proof (1668) that luminous wood requires air to produce light, and Heller's demonstration (1853) that the light emanating from decayed wood is fungal in origin. The continuing interest in fungal bioluminescence is reflected by the subject's inclusion in many twentieth century textbooks and popular books on mycology. Among the more recent accounts of bioluminescence in fungi are those by Buller (1924), Rolfe and Rolfe (1925), Wassink (1948,1979), Ramsbottom (1953), Harvey (1957), and Findlay (1967). Recently we encountered several accounts of fungal bioluminescence dating from the sixteenth, seventeenth, and eighteenth centuries that either were not cited in these works or were incompletely discussed. In addition to the intrinsic interest of the subject matter, these accounts serve as examples of how mycological discoveries were made and the results disseminated during the crucial era when modern science was beginning to flourish. Accordingly, herein we discuss these early records in relation to the science and scholarship of their times. The earliest reference to fungal bioluminescence by an American author appears to be that by Cotton Mather (1663-1728). Mather mentions the subject in The Christian Philosopher: A Collection of the Best Discoveries in Nature, with Religious Improvements. The manuscript was completed in 1715 and the book was published in England in 1720, although it bears an imprint of 1721. Mather's (1721) avowed purpose was to demonstrate "that Philosophy is no Enemy, but a mighty and wondrous Incentive to Religion." The organization of the book reflects the traditional Aristotelian view of nature. Mather
III-V Nanowire-based Solar Cells on Si and Graphene

Overcoming lattice matching restrictions for conventional heteroepitaxy, solar cells based on III-V compound semiconductor nanowires grown on silicon and graphene substrates will be demonstrated.
ALEGRA based computation of magnetostatic configurations

We explore how reliable the ALEGRA MHD code is in its static limit. Also, we explore (in the quasi-static approximation) the process of evolution of the magnetic fields inside and outside an inclusion and the parameters for which the quasi-static approach provides for self-consistent results.
Spontaneous bilateral torsion of fallopian tubes presenting as primary infertility

Case presented at “Stump the Professors” 44th American Association of Gynecologic Laparoscopists Global Congress on Minimally Invasive Gynecology, NV, USA, 15–19 November 2015 Background: Spontaneous torsion of the fallopian tubes is a rare condition, usually seen in acute settings or as incidental findings during laparoscopy. Presentation of the case: A 34-year-old nulligravid woman with inability to conceive for 7 months presented to our center. Her hysterosalpingography revealed a blind-ending right fallopian tube, and a blocked and dilated left fallopian tube. Laparoscopy showed a long, auto-amputated right fallopian tube, disconnected from the fimbriae and a long, dilated left fallopian tube, with several twists around its axis. Bilateral salpingectomy was performed. The patient subsequently underwent IVF, resulting in an ongoing pregnancy. Conclusion: Spontaneous torsion of the fallopian tubes can manifest as primary infertility without any antecedent symptoms, and should be considered in the differ...
Small-on-Large Theory with Applications to Granular Materials and Fluid/Solid Systems

Some mechanics involved in calculating wave speeds in pre-stressed materials of geophysical interest are discussed. Two topics are explored: granular materials, and fluid-solid composite systems. Elasticity in the granular material is dominated by intergranular contact which produces strong nonlinearity. The contact also introduces possible hysteresis and loss of strict macroscopic hyperelasticity. Starting with the Hertz solution for two spheres, these notes develop the theory to the stage where macroscopic elastic properties can be estimated, and the stress dependence of bulk waves calculated. Fluid-solid composite systems, such as a fluid-filled borehole in an elastic solid, are complicated by the ability of the fluid to slip under pre-stress. The interface conditions in the different material descriptions are examined and a procedure is described to determine the modified wave speed using a perturbation integral approach. The example of the fundamental guided mode of the borehole, the tube wave, is described in detail.
Internal mammary artery grafting. Clinical results, patency rates, and long-term survival in 833 patients.

This report reviews 833 patients who underwent internal mammary artery grafting alone or with vein grafts between 1968 and 1981. Use of the internal mammary artery was indicated in young or middle-aged patients with the following characteristics: a significant lesion of the proximal left anterior descending artery or its diagonal branch alone (70.1 %) or combined with diffuse atherosclerosis (19.9 %) or a small caliber (3.4%); absent or unsuitable veins for grafting (5.5%); atherosclerosis or an aneurysm of the ascending aorta (0.6%); and failure of previous vein grafts (0.5%). The left anterior descending artery system was grafted by the left internal mammary artery in 53.2%, and the arterial graft was complimented by vein grafts in 2.6%. In 45.2% of the patients, grafts of the left anterior descending artery by the left internal mammary artery were supplemented by vein grafts to the right coronary artery (23.8 %) to the circumflex artery (15.2 %) or to both (6.2 %). The overall operative mortality was 2.2 %. It rose to 16.7 % with associated cardiac procedures and to 18.5 % in patients who were in New York Heart Association Class IV. If these two high-risk categories of patients are excluded, the perioperative death rate in the remaining 750 was only 0.4%. Of the 815 patients who survived the perioperative period (mean 53.1 months follow-up), 63.1 % were relieved of angina and 83.4 % were in Class I or II of the New York Heart Association, as compared to 27.4 % before the operation. At cardiac recatheterization (mean 18.9 months), 87.9 % of the internal mammary artery grafts and 63.3 % of the vein grafts were patent (p
The Immediate Impact of the 2009 USPSTF Screening Guideline Change on Physician Recommendation of a Screening Mammogram: Findings from a National Ambulatory and Medical Care Survey-Based Study

Regular screening is considered the most effective method to reduce the mortality and morbidity associated with breast cancer. Nevertheless, contradictory evidence about screening mammograms has led to periodic changes and considerable variations among different screening guidelines. This study is the first to examine the immediate impact of the 2009 US Preventive Services Task Force (USPSTF) guideline modification on physician recommendation of mammograms. The study included visits by women aged 40 years and older without prior breast cancer from the National Ambulatory and Medical Care Survey 2008-2010. Bivariate and multiple logistic regressions were used to determine the factors associated with mammography recommendation. Approximately 29,395 visits were included and mammography was recommended during 1350 visits; 50-64-year-old women had 72% higher odds, and 65-74-year-old women had twice the odds of getting a mammogram recommendation compared with 40-49-year-old women in 2009. However, there was no difference in recommendation by age groups in 2008 and 2010. Obstetricians and gynecologists did not modify their recommendation behavior in 2009, unlike all other specialists who reduced their recommendation for 40-49-year-old women in 2009. Other characteristics associated with mammogram recommendations were certain patient comorbidities, physician specialty and primary care physician status, health maintenance organization status of the clinic, and certain visit characteristics. This study demonstrated a temporary effect of the USPSTF screening guideline change on mammogram recommendation. However, in light of conflicting recommendations by different guidelines, the physicians erred toward the more rigorous guidelines and did not permanently reduce their mammogram recommendation for women aged 40-49 years.
Global mass violence: examining racial and gendered violence in the twilight of multiculturalism

ABSTRACTThis article examines three instances of mass violence for what they tell us about the inadequacies of post-racial and colourblind discourses in the US and Europe. I apply an intersectional analysis of the manifestoes that Anders Behring Breivik, Elliot Rodger and Dylann Roof leave in the wake of their horrific acts. These manifestoes, in their appropriation of rights discourses and desire for a white racial order, expose the ambivalent commitments to persons of colour evident in the current retreat of many Western states from multiculturalist ideals in favour of post-racial integration. These states now advocate policies of integration over previous emphases on multiculturalism and diversity, a move that reflects the growing popular promotion of national identity and nativist culture. I argue that such incidents of mass violence should be understood in relation to the political, social and cultural contexts that perpetuate and often legitimate xenophobia and gendered racism.
Priming Performance of Economics Students: Even More Evidence

John Bargh (2006) and several others have established that subtle, subconscious cues can affect test subjects’ behavior in a laboratory setting — the so-called “priming effect.” For example, Bargh, Chen, & Burrows (1996) found that participants primed with an elderly stereotype walked more slowly down the hallway when leaving the experiment compared to members of the control group. Dijksterhuis (1998) showed that priming test subjects (again, in a laboratory setting) for intelligence via exposure to an image of a professor increased performance on a general knowledge test, and priming subjects with stupidity or the stereotype of a soccer hooligan reduced scores measuring general knowledge. In three separate experiments, we primed college students either for high performance or low performance in a classroom environment. Multiple groups of students (n=306) from four colleges — one flagship state university (R2), two state universities (M1), and a community college — were either primed with images of Steve Jobs, Nick Saban, or Bill Gates (high performance), or were primed with images of Napoleon Dynamite or Bluto from Animal House (low performance). Students then watched videos of economics lectures in a classroom setting and then quizzed on lecture content. Students primed with high performance significantly outperformed those students primed for low performance.
Size-Controlled Pd Nanoparticle Catalysts Prepared by Galvanic Displacement into a Porous Si-Iron Oxide Nanoparticle Host.

Porous silicon nanoparticles containing both Pd and iron oxide nanoparticles are prepared and studied as magnetically recoverable catalysts for organic reductions. The Pd nanoparticles are generated in situ by electroless deposition of Pd(NH3)42+, where the porous Si skeleton acts as both a template and as a reducing agent and the released ammonia ligands raise the local pH to exert control over the size of the Pd nanoparticles. The nanocomposites are characterized by transmission electron microscopy, energy-dispersive X-ray spectroscopy, nitrogen adsorption, X-ray diffraction, superconducting quantum interference device magnetization, and dynamic light scattering. The nanocomposite consists of a porous Si nanoparticle (150 nm mean diameter) containing ∼20 nm pores, uniformly decorated with a high loading of surfactant-free Pd nanoparticles (12 nm mean diameter) and superparamagnetic γ-Fe2O3 nanoparticles (∼7 nm mean diameter). The reduction of 4-nitrophenol to 4-aminophenol by sodium borohydride is catal...
Phylogenetic taxonomy and classification of the Crinoidea (Echinodermata)

A major goal of biological classification is to provide a system that conveys phylogenetic relationships while facilitating lucid communication among researchers. Phylogenetic taxonomy is a useful framework for defining clades and delineating their taxonomic content according to well-supported phylogenetic hypotheses. The Crinoidea (Echinodermata) is one of the five major clades of living echinoderms and has a rich fossil record spanning nearly a half billion years. Using principles of phylogenetic taxonomy and recent phylogenetic analyses, we provide the first phylogeny-based definition for the Clade Crinoidea and its constituent subclades. A series of stem- and node-based definitions are provided for all major taxa traditionally recognized within the Crinoidea, including the Camerata, Disparida, Hybocrinida, Cladida, Flexibilia, and Articulata. Following recommendations proposed in recent revisions, we recognize several new clades, including the Eucamerata Cole 2017, Porocrinoidea Wright 2017, and Eucladida Wright 2017. In addition, recent phylogenetic analyses support the resurrection of two names previously abandoned in the crinoid taxonomic literature: the Pentacrinoidea Jaekel, 1918 and Inadunata Wachsmuth and Springer, 1885. Last, a phylogenetic perspective is used to inform a comprehensive revision of the traditional rank-based classification. Although an attempt was made to minimize changes to the rank-based system, numerous changes were necessary in some cases to achieve monophyly. These phylogeny-based classifications provide a useful template for paleontologists, biologists, and non-experts alike to better explore evolutionary patterns and processes with fossil and living crinoids.
The Faculty of the Future

This paper examines some implications of predicted demographic changes in Canadian universities that may make them unable to replace retiring faculty members in numbers permitting academic business as usual. If the predictions prove correct, it will be desirable to reinterpret received verities about the relationship between professor/student ratios and effective education, the dual roles of teaching and research, and democratic governance in communities of higher education. Possibilities for restructuring inquiry and instruction in ways consistent with the responsibilities of educators are all too briefly explored. A revised division of instructional labour is suggested, along with changes in the conduct of research and academic administration that would free professors to focus on the tasks for which they have the greatest expertise.
Thermal properties of 3-D printed polylactic acid-metal composites

Standard fused filament fabrication (FFF)-based 3-D printers fabricate parts from thermopolymers, such as polylactic acid (PLA). A new range of metal based PLA composites are available providing a novel range of potential engineering materials for such 3-D printers. Currently, limited material data, specifically thermal property characterization is available on these composites. As a result, the application of these materials into functional engineered systems is not possible. This study aims to fill the knowledge gap by quantifying the thermal properties of copperFill, bronzeFill, magnetic iron PLA, and stainless steel PLA composites and provide insight into the technical considerations of FFF composite 3-D printing. Specifically, in this study the correlation of the composite microstructure and printing parameters are explored and the results of thermal conductivity analysis as a function of printed matrix properties are provided. Considering the relative deviation from the filament raw bulk analysis, the results show the printing operation significantly impacts the resultant component density. Experimentally collected thermal conductivity values, however, do not correlate to the theoretical models in the literature and more rigorous quantitative exercises are required to determine true percent porosity to accurately model the effect of air pore volume fraction on thermal conductivity. Despite this limitation, the thermal conductivity values provided can be used to engineer thermal conductivity into 3-D printed parts with these PLA-based composites. Finally, several high-value applications of such 3-D printed materials that look metallic, but have low thermal conductivity are reviewed.
High precision yet wide range on-chip oscillator with dual charge-discharge technique

This paper describes a high precision all digital on-chip oscillator. This architecture can achieve absolute precisions beyond 0.1% with only one trim. Once trimmed, the oscillator can produce any frequency within the programmable range with similar accuracy. If there are multiple oscillators on same die, trimming one oscillator will be sufficient to trim all the oscillators at multiple frequencies. The designed prototype achieved better than 0.17% accuracy at 112MHz while consuming 250uA. The area for the oscillator is just 0.02mm2.
Memory Is a Strange Country

When the 12 memories of a Proof of Age are read as a single document, they usually focus on a few familiar themes and it is easy to see how the jurors shared a common village life. In a few Proofs there was even a “theme” that covered at least half the memories: a gift for the mother at her churching, the death of valuable animals, and so on. In many Proofs there were joint memories: four men said as one that they had seen the priest write the date of the baptism, and many more statements of this sort. But there were some odd memories and we wonder that only one juror went back to that event: a comet, the burning of a Lollard, deaths from the plague. So in aggregate the hundreds of Proofs attest to the common threads that run through lives that share culture and class (and gender) and they also provide an occasional glimpse into a few once-and-only events that were offered as a memory to mark the year under consideration.
Leveraging Spatial Diversity for Privacy-Aware Location-Based Services in Mobile Networks

While providing unprecedented convenience to people’s daily life, location-based services (LBSs) may cause serious concerns on users’ location privacy, when the system is compromised. Although various location privacy protection mechanisms have been developed for LBSs, the ambient physical environment often imposes some fundamental limitations on their performances. As a result, mobile users may experience a spatial diversity in the achievable location privacy when traveling along their routes. However, to the best of our knowledge, an appropriate location privacy metric that can capture the influence of the ambient environment is still missing in the literature. Also, none of the existing location privacy protection methods can properly leverage such spatial diversity. With this consideration, new ambient environment-dependent location privacy metrics are proposed in this paper, together with a stochastic model that can capture their spatial variations along the user’s route. Based on this modeling, a new optimal stopping-based LBS access scheme that allows mobile users to fully leverage the spatial diversity and achieve a substantially better performance is developed. The effectiveness of the proposed scheme is corroborated by both numerical results and simulations over real-world road maps.
Transient‐Ligand‐Enabled ortho‐Arylation of Five‐Membered Heterocycles: Facile Access to Mechanochromic Materials

Reported herein is the first example of a direct arylation of heteroarenes by a transient-ligand-directed strategy without the need to construct and deconstruct the directing group. A wide range of heteroarenes undergoes the coupling with diverse aryl iodides to assemble a large library of highly selective and functionalized 3-arylthiophene-2-carbaldehydes. This route provides an opportunity to rapidly access new mechanofluorochromic materials. Moreover, a novel strategy for mechanochromic luminogens with chromism trends of red- and blue-shifts has been disclosed for the first time by facile functional-group modifications to a common structural core.