cssi/SciSciGPT-SciSciNet huggingface dataset:
Industrial ecology in motion through enterprise integration

As the next millennium approaches, effective product stewardship strategies require that computer manufacturers put in motion industrial ecology principles of optimizing the materials life cycle from the product's final disposal. One method is aggressively embracing enterprise integration-the linking of organizations, companies and communities with the goal of making environmental considerations a part of every activity. This paper describes how IBM and the industry are responding-and must respond even further-to shifting environmental awareness around the world, the explosive growth of electronic products, technical challenges to solving global environmental problems, and regulatory challenges posed by governments around the world.
Alterations in the Density of Interstitial Cells of Cajal in Achalasia

The aim of this study was to assess the quantity of interstitial cells of Cajal (ICC) in the lower esophageal sphincter (LES) in achalasia. LES muscle was obtained from 11 achalasia and nine esophageal cancer (control) patients during surgery. Immunohistochemistry was performed and average cell counts per high-power field (HPF) were obtained. Overall, more ICC were observed in achalasia (median = 14.0 cells/HPF; range = 0–22.6 cells/HPF) as compared with controls (median = 6.2 cells/HPF; range = 1.6–10.8 cells/HPF) (P = 0.047). There were two subsets of findings within the achalasia group: 8/11(73%) had an increased quantity of ICC (median = 17.1 cells/HPF; range = 11.6–22.6; P = 0.015) as compared with controls, whereas the remaining 3/11(27%) had a paucity of ICC (median = 0 cells/HPF; range = 0–2; P = 0.02). ICC levels were positively correlated with age of the patient (P = 0.043). Our study demonstrates that subsets of abnormal ICC levels are observed in idiopathic achalasia of the esophagus.
Bandwidth control in acoustically coupled AlN contour mode MEMS filters

This paper reports a novel method to acoustically couple higher order AlN contour mode resonators and engineer wide bandwidth filters by controlling the number of electrodes, the size of the overhang and the spacing between electrodes. By exciting a higher order resonance mode using multiple metal electrodes on one side of the device and picking up the generated signal on the other, the location of the response poles can be engineered to create a broader band, wider than previously achieved with similar AlN contour-mode devices. CAD-level parameters are experimentally shown to set the location of the poles and therefore the bandwidth.
Simulating MIMO techniques in a reverberation chamber

We present a general method for over-the-air test of antenna setups and/or post-processing algorithms used in advanced transmission schemes. The method utilizes a reverberation chamber to simulate various levels of multipath in the propagation environment. Multipath is essential for correctly estimating the performance of multiple-antenna systems. Our test set-up enables measurement of data throughput with standard laboratory instruments. With this test set-up, antenna setups can be studied while isolated from any specific system hardware implementation.
Ab initio Molecular Dynamics Simulations of the Hydroxylation of Nanoporous Silica

Accurate information on the interactions between water and silica is critical to the understanding of its properties including mechanical strength under stress and long-term chemical durability of silica and silicate glasses. In this study, interactions between water and nanoporous amorphous silica models were investigated using density functional theory (DFT) based ab initio molecular dynamics (AIMD) simulations which accurately describe bond breakage and formation as well as chemical reactions. AIMD simulations up to 30 ps were performed for systems containing water and nanoporous silica with a wide range of porosities (31%–67%). Partial removal of defects, such as two-membered rings, was observed during the AIMD runs whereas more reactive coordination defects were removed during the initial geometry optimization. The limited two-membered ring removal can be attributed to restricted water-defect movement or the increased stability of rings located on concave surfaces. Two-membered ring removal mechanisms included the formation of an overcoordinated silicon (Si5) intermediate defect from the dynamic simulations. Si5 defects continued to develop throughout the simulations, indicating a thermodynamic drive for two-membered ring removal which is kinetically limited. Changes in the electronic structures, such as atomic charges, and bond length-bond angle correlation functions were monitored during the hydroxylation process.
Hypertextual border crossing: students and teachers, texts and contexts

Abstract Collaborative hypertext writing in the college classroom can underwrite a pedagogy rooted in the cultural hybridity bell hooks has argued is central to progressive educational methodology. This article offers a narrative of the collaborative creation of a HyperCard hypertext called the E.A.R., and describes how the ideas developed in that project were adapted into a first-year composition course. In exploring the creation of a collaborative hypertext, we hope to gain insight into both the larger aims of the border crossings central to hooks’ ongoing project and the more local goals of hypertext pedagogy.
Dual-band reactively loaded microstrip antenna

A previously derived theory is applied to a microstrip antenna with a reactive load to produce a dual-band radiator. A model consisting of a rectangular patch radiator loaded with a variable length short-circuited coaxial stub was investigated experimentally. Comparisons of theoretical predictions and experimental data are made for the impedance and resonant frequencies as a function of the position of the load, the length of the stub, and the characteristic impedance of the stub.
An Analysis of Sand Filtration

Relationship for distribution of sediment in filter in terms of space time coordinates and physical properties of components of system; development of fundamental equation; gravitational sedimentation theory; experimental verification of theory.
Extrusion-Shaping of Curved Hose Reinforced with Short Cellulose Fibers

Abstract A new development in hose technology, the direct shaping of curved hose reinforced with short fibers at the extrusion die, is described. By moving the inner and outer portions of the tube die out of concentricity in a programmed sequence, the extrusion direction can be made to deviate from the machine axis and thus to produce bends in the hose. This process has been demonstrated on planar S-bends of a 38 mm hose. Bend radii as tight as 13 mm to the inside of the bend are feasible. Such a hose might find various industrial applications. Performance characteristics are similar to cord reinforced coolant hoses. The reproducibility of the die motions and timing sequences to produce the hose shapes are maintained by a digitally controlled hydraulic cylinder that is driven through a stepper motor. The driver for the stepper motor could involve hard-wired or microprocessor circuitry. All of the components for this system are commercially available with the exception of a customized extrusion head to acc...
Trauma and Child Health: An Introduction to the Special Issue

Potentially traumatic events are common occurrences that can lead to significant psychological distress, and yet, there has been remarkably little attention to the associations between traumatic events and youth's physical health. The articles contained in this Special Issue of the Journal of Pediatric Psychology represent a significant step forward in the establishment of "Trauma and Child Health" as a major area of study within the field of pediatric psychology. In this introductory article, we briefly describe several contextual issues that may help to set the stage for the articles contained in this Special Issue. These contextual issues include the most common types of traumatic events that are studied, as well as the features of traumatic events that may affect physical and mental health outcomes, such as whether casualties or interpersonal violence is involved.
Metabolic Analysis of Striatal Tissues from Parkinson’s Disease-like Rats by Electrospray Ionization Ion Mobility Mass Spectrometry

Electrospray ionization ion mobility mass spectrometry (ESI-IMMS) was used to study the striatal metabolomes in a Parkinson’s like disease (PD-like) rat model. Striatal tissue samples from Berlin Druckrey IV (BD-IV) with PD-like disease 20 dpn-affected and 15 dpn-affected rats (dpn: days postnatal) were investigated and compared with age-matched controls. An ion mobility mass spectrometer (IMMS) produced multidimensional spectra with mass to charge ratio (m/z), ion mobility drift time, and intensity information for each individual metabolite. Principle component analysis (PCA) was applied in this study for pattern recognition and significant metabolites selection (68% data was modeled in PCA). Both IMMS spectra and PCA results showed that there were clear global metabolic differences between PD-like samples and healthy controls. Nine metabolites were selected by PCA and identified as potential biomarkers using the Human Metabolome Database (HMDB). One targeted metabolite in this study was dopamine. Select...
An Interpolation Proof of Ehrhard’s Inequality

We prove Ehrhard’s inequality using interpolation along the Ornstein–Uhlenbeck semi-group. We also provide an improved Jensen inequality for Gaussian variables that might be of independent interest.
Identification of insulin-like growth factor binding proteins in human oviduct.

Objective To determine if human oviduct expresses messenger ribonucleic acids (mRNAs) encoding insulin-like growth factor binding proteins (IGFBPs), if oviductal epithelium secretes IGFBPs into conditioned medium (CM), and if IGFBP secretion is regulated by steroid hormones. Design Northern blots of RNA, isolated from late proliferative phase human fimbria and oviductal isthmus, were probed with complementary deoxyribonucleic acids encoding IGFBP-1, IGFBP-2, IGFBP-3, and IGFBP-4. In addition, oviductal ampullary epithelial cells were cultured with and without estrogen and/or progesterone (P), and IGFBPs were examined in CM by Western ligand blot analysis and identified using specific antisera. Setting Tissue was obtained from hysterectomy specimens at Stanford University Hospital, a private teaching institution. Patients, Participants Patients undergoing hysterectomy for benign disease. Interventions None. Main Outcome Measures Transcripts of IGFBP mRNA and IGFBPs secreted into CM were detected by autoradiography of Northern and Western ligand blots, respectively. Results Messenger RNA transcripts encoding IGFBP-2, -3, and -4 were detected, whereas IGFBP-1 mRNA was barely detectable in oviductal tissue. In CM, IGFBP-2 and IGFBP-3 were detected, as was a unique 24–kd IGFBP, although IGFBP-1 was not observed. Estrogen and/or P did not regulate the secretion of these IGFBPs by cultured oviductal epithelium. Conclusions Human oviduct expresses mRNAs encoding IGFBP-2, IGFBP-3, and IGFBP-4, and in vitro oviductal epithelium secretes IGFBP-2, IGFBP-3, and a unique binding protein of 24 kd, which may be the recently identified IGFBP-4.
Case Studies of EM Algorithm with Masked Data

As an alternative to conventional MLE approach, the Expectation-Maximization (EM) algorithm is now widely used for maximum likelihood estimation when data is incomplete. The EM algorithm is remarkable because of its simplicity, generality and convergence. However, such good characteristics of the EM algorithm may lead to less attention to the validity of the MLE problem. Though we can always have solutions when applying the EM algorithm, the solutions may not be meaningful when the MLE problem itself is inappropriate in the first place. In this paper, we demonstrate through case studies that the MLE problem can be inappropriate and the results of the EM algorithm can be misleading. As examples, we estimate the failure probability of two components with masked system test data. We apply both the conventional MLE approach and the EM algorithm. Their results are compared. We show that the process of applying conventional approach may easily expose the inappropriateness of the MLE problem while the EM algorithm may not. We conclude that we should check the validity of the data and corresponding MLE problem before we apply the EM algorithm.
Doulas for surgical management of miscarriage and abortion: a randomized controlled trial

Background Women undergoing office-based surgical management of a failed or undesired pregnancy often report fear of pain and anxiety pertaining to the procedure. Doulas are trained to specifically address women's physical and emotional needs in obstetric care, and recently have extended their practice to support women through all pregnancy outcomes. Objective We sought to evaluate the impact of doulas on patients' physical and emotional responses to surgical management of a first-trimester failed or undesired pregnancy under local anesthesia. Study Design In this nonblinded, randomized trial, women received doula support or routine care during office uterine aspiration for failed or unwanted pregnancies in the first trimester. The primary outcome was pain measured on a 100-mm visual analog scale. Secondary outcomes included satisfaction, emotional state, sense of personal empowerment, and ability to cope immediately and 1 month after the procedure, as well as medical assistants' assessment of the doula's utility. A sample size of 35 per group (N = 70) was planned to detect a 20% difference in pain score. Results From April 2014 through January 2015, 129 women were screened and 70 were randomized. The 2 study groups were similar on all baseline characteristics. The primary outcome was not different between the doula and control groups (pain score 70.7 ± 24.5 mm vs 59.7 ± 32.5 mm, P = .11, respectively), even after controlling for procedure indication ( P = .20). While 97% of women who received doula support reported this helped with their experience, there was no statistically significant difference in satisfaction, emotional response, sense of empowerment, or perceived ability to cope between the 2 groups of women immediately following or 1 month after the procedure. Of all study participants, 72% reported that it was important to have someone with them during the procedure, but that the support person did not have to be a doula. Conclusion Doula support during office uterine aspiration for failed or undesired pregnancies is well received and desired by women undergoing this procedure despite no significant effect on physical comfort or emotional responses related to the procedure. This may suggest an unmet psychosocial need for procedure-related support among such women.
Electromagnetic Navigation Bronchoscopy

Electromagnetic navigation bronchoscopy (ENB) has been in continuous evolution since its introduction in 2004. The basic components of this global positioning system-like technology include a magnetic field generator, a sensor and computer integration, and a computed tomography scan used as a three-dimensional map. Its value has been documented for individuals with small peripheral pulmonary nodules and clearly represents a significant improvement over standard non-guided bronchoscopy. Variances and worldwide practice have shown how ENB fits into regional work flows and opens several important questions about the values of adjunct technology such as fluoroscopy, peripheral ultrasound, biopsy technique, and anesthesia technique, etc. This chapter reviews the literature on ENB and discusses the evolution as well as the technical aspects of the procedure. Also described is the ideal patient population based on the literature and our own expertise.
Subsurface Fault Damage Zone of the 2014 Mw 6.0 South Napa, California, Earthquake Viewed from Fault‐Zone Trapped Waves

The aftershocks of the 24 August 2014 M w 6.0 South Napa earthquake generated prominent fault‐zone trapped waves (FZTWs) that were recorded on two 1.9‐km‐long seismic arrays deployed across the northern projection (array 1, A1) and the southern part (A2) of the surface rupture of the West Napa fault zone (WNFZ). We also observed FZTWs on an array (A3) deployed across the intersection of the Franklin and Southampton faults, which appear to be the southward continuations of the WNFZ. A1, A2, and A3 consisted of 20, 20, and 10 L28 (4.5 Hz) three‐component seismographs. We analyzed waveforms of FZTWs from 55 aftershocks in both time and frequency to characterize the fault damage zone associated with this M w 6.0 earthquake. Post‐ S coda durations of FZTWs increase with epicentral distances and focal depths from the recording arrays, suggesting a low‐velocity waveguide along the WNFZ to depths in excess of 5–7 km. Locations of the aftershocks showing FZTWs, combined with 3D finite‐difference simulations, suggest the subsurface rupture zone having an S ‐wave speed reduction of ∼40%–50% between A1 and A2, coincident with the ∼14‐km‐long mapped surface rupture zone and at least an ∼500‐m‐wide deformation zone. The low‐velocity waveguide along the WNFZ extends further southward to at least A3, but with a more moderate‐velocity reduction of 30%–35% at ray depth. This last FZTW observation suggests continuity between the WNFZ and Franklin fault. The waveguide effect may have localized and amplified ground shaking along the WNFZ and the faults farther to the south (see a companion paper by Catchings et al. , 2016).
Artificial neural networks: Predicting head CT findings in elderly patients presenting with minor head injury after a fall *

Abstract Objectives: To construct an artificial neural network (ANN) model that can predict the presence of acute CT findings with both high sensitivity and high specificity when applied to the population of patients≥age 65years who have incurred minor head injury after a fall. Methods: An ANN was created in the Python programming language using a population of 514 patients ≥ age 65 years presenting to the ED with minor head injury after a fall. The patient dataset was divided into three parts: 60% for "training", 20% for "cross validation", and 20% for "testing". Sensitivity, specificity, positive and negative predictive values, and accuracy were determined by comparing the model's predictions to the actual correct answers for each patient. Results: On the "cross validation" data, the model attained a sensitivity ("recall") of 100.00%, specificity of 78.95%, PPV ("precision") of 78.95%, NPV of 100.00%, and accuracy of 88.24% in detecting the presence of positive head CTs. On the "test" data, the model attained a sensitivity of 97.78%, specificity of 89.47%, PPV of 88.00%, NPV of 98.08%, and accuracy of 93.14% in detecting the presence of positive head CTs. Conclusions: ANNs show great potential for predicting CT findings in the population of patients ≥ 65 years of age presenting with minor head injury after a fall. As a good first step, the ANN showed comparable sensitivity, predictive values, and accuracy, with a much higher specificity than the existing decision rules in clinical usage for predicting head CTs with acute intracranial findings.
Establishment and characterization of a human primary prostatic adenocarcinoma cell line (ND-1).

AbstractA human primary prostatic adenocarcinoma cell line named ND-1 has been established in long term tissue culture. The cultured cells show growth in both monolayers and in soft agar suspension and produce subcutaneous tumors in nude mice. Cytogenetic analysis by G-banding demonstrated an aneuploid karyotype with a modal chromosome number of 62, and multiple marker chromosomes with 25-30% structural abnormalities. Ploidy analysis revealed that the majority of ND-1 cells (67%) had a DNA mass of 10.1 picogram and DNA index of 1.41. Nineteen percent of cells had a DNA mass of 21.3 picogram and DNA index of 3.0. Electron microscopic studies revealed common features of neoplastic epithelial cells such as numerous microvilli, junctional complexes, abnormal nuclei, nucleoli, and mitochondria. Due to the absence of a structurally normal Y chromosome, confirmation of the presence of a derived Y chromosome was achieved through the use of C-banding and through fluorescent in situ hybridization with a Y chromosom...
Effect of electrode sub-micron surface feature size on current generation of Shewanella oneidensis in microbial fuel cells

Abstract Microbial fuel cells (MFCs) are envisioned to serve as compact and sustainable sources of energy; however, low current and power density have hindered their widespread use. Introduction of 3D micro/nanostructures on the MFC anode is known to improve its performance by increasing the surface area available for bacteria attachment; however, the role of the feature size remains poorly understood. To delineate the role of feature size from the ensuing surface area increase, nanostructures with feature heights of 115 nm and 300 nm, both at a height to width aspect ratio of 0.3, are fabricated in a grid pattern on glassy carbon electrodes (GCEs). Areal current densities and bacteria attachment densities of the patterned and unpatterned GCEs are compared using Shewanella oneidensis Δ bfe in a three-electrode bioreactor. The 115 nm features elicit a remarkable 40% increase in current density and a 78% increase in bacterial attachment density, whereas the GCE with 300 nm pattern does not exhibit significant change in current density or bacterial attachment density. The current density dependency on feature size is maintained over the entire 160 h experiment. Thus, optimally sized surface features have a substantial effect on current production that is independent of their effect on surface area.
“I catch whatever’s biting!”: Motivations, constraints, and facilitators of no-preference anglers residing along New York’s Lake Ontario Coast

A survey of 7000 property owners in the seven counties bordering Lake Ontario in New York State was conducted to examine the relationships among motivations, constraints, facilitators, demographic and experiential characteristics, and fishing participation for resident anglers who did not have a preference for catching a specific fish species (i.e., ‘no-preference’ resident anglers). Understanding the relationships among these elements is important for fisheries promoters and business owners seeking to attract this large angler market. A total of 1303 questionnaires were returned, 681 of which were completed by anglers; 210 of these anglers self-identified as “no-preference” anglers. Two factor analyses (i.e., for motivations and facilitators/constraints) confirmed nine motivations and ten facilitators/constraints for “no preference” anglers. Path analysis results indicate that level of commitment to fishing (facilitator), economic costs associated with fishing (constraint), and nurture (passing on fishing knowledge and traditions to others; motivation) directly influenced fishing participation for responding no-preference anglers; several motivations, constraints, facilitators, and demographic characteristics indirectly influenced participation as well.
What If Pennoyer Was Right

In Pennoyer Was Right, 125 Texas Law Review 1249 (2017), Professor Stephen Sachs argues for a return to Pennoyer v. Neff’s understanding of the Fourteenth Amendment Due Process Clause. In that understanding, the Clause imposes a federal requirement that judgments be supported by personal jurisdiction but does not create a federal standard for assessing when the exercise of personal jurisdiction is appropriate. The relevant standard comes instead from general law — primarily, customary international law (CIL). In this response, I consider conceptual, practical, and normative implications of Sach’s argument. In particular, I argue that Sach’s view of the Due Process Clause bears on the debate in U.S. Foreign Relations Law over the domestic legal status of CIL. Sach’s understanding of the Clause provides another example of how CIL might play a role in domestic law under the revisionist view in that debate.
Abstract WP1: Evaluation of Clinical and Radiographic Variables Related to False Positive Detection of Tandem Carotid Artery Occlusion on CT Angiography

Background and purpose: CT angiography has been shown to result in up to 30% false positive detection of extracranial ICA occlusion in patients with acute ICA terminus occlusion. This may confound planning for acute endovascular intervention and cause inaccurate patient exclusion from related clinical trials of acute stroke therapy. We explored demographic, clinical variables, recanalization rates and outcomes that are associated with this radiographic artifact. Methods: Retrospective review of a prospectively maintained database of acute endovascular therapy at UPMC between 2002 and 2015. Patients with isolated terminus ICA occlusion were selected from a previously derived cohort of cases with or without pseudo-occlusion of the extracranical ICA on pre-procedural CTA (false positives and true negatives). Comparisons between these two groups were evaluated with univariate analysis. Results: We reviewed 69 cases of isolated ICA terminus occlusion. 21 patients had false-positive occlusion of the extracranial ICA (group 1) and 48 patients had adequate CTA diagnosis (true negatives, group 2). Rates of IV tPA (33% vs. 29%) and median CTA to groin puncture time (98 vs. 80 min) were similar between the two groups. Terminus ICA occlusion types were as follows: ICA-I (19% vs 6 %), ICA-L (67% vs. 56%), ICA-T (14% vs. 37%). Manual aspiration thrombectomy was used in 68% of cases in group 1 compared to 38% of cases in group 2 (P=0.03), no difference in use of recanalization devices were found. TICI 2b/3 recanalization was achieved to similar extent (42% vs. 33%). Favorable outcome (90-day modified Rankin Scale ≤ 2) was achieved in 26% vs. 40% between the two groups (P=0.52). Conclusions: Patients with acute terminus ICA occlusion who are misclassified as having tandem ICA occlusions on CTA have similar characteristics than their respective controls in this small cohort. Although future studies with larger sample sizes are needed to tease out preliminary trends, the data support the need for optimization of current screening methods for tandem ICA occlusion in the acute setting.
EL ARTE COMO MANIPULACIÓN EN ABY WARBURG

Al definir al hombre, Aby Warburg pone al centro de su consideracion el concepto de manipulacion. La existencia humana estaria caracterizada por el contacto con objetos externos, lo cual se aprecia tanto en el uso de utensilios como en la creacion artistica. Mientras para el primer caso Warburg habla de un sentimiento tragico producto de la extension de lo organico a lo inorganico del objeto, en el caso del arte la nocion de tragedia es omitida. Este articulo propone una interpretacion de esta diferencia sostenida en el analisis comparativo de textos de Warburg y de algunos autores que lo infl uenciaron.
Corrigendum to “The Schwarz alternating method in solid mechanics” [Comput. Methods Appl. Mech. Engrg. 319 (2017) 19–51]

Abstract This corrigendum clarifies the conditions under which the proof of convergence of Theorem 1 from the original article is valid. We erroneously stated as one of the conditions for the Schwarz alternating method to converge that the energy functional be strictly convex for the solid mechanics problem. We have relaxed that assumption and changed the corresponding parts of the text. None of the results or other parts of the original article are affected.
Ultra-Wideband Radar for Robust Inspection Drone in Underground Coal Mines

Coal mines pose a high safety risk for human workers. An autonomous inspection drone would enable a coal mine operation to reduce this risk by minimizing the time spent by workers inside the mine. This inspection drone must be highly robust to the harsh and dangerous environment of an underground coal mine, with high levels of coal dust and humidity that can obstruct many conventional sensing methods. For high functionality, the drone must sense and avoid potential obstacles and as well as inspect and map the mining wall face. The objective of this paper is to present ultra-wideband (UWB) radar as a robust sensing solution to this challenging environment and validate its performance experimentally in the typical coal mine environment, both statically and dynamically.
External loading is dependent upon game state and varies by position in professional women’s soccer

Objectives: This investigation examined relationships between game state and external loading in professional women’s soccer. Methods: Match motion and accelerometer data were collected and used to...
Augmenting Food Experience While Traveling Abroad by Using Mobile Augmented Reality Application

Local cuisine is an essential part of a travel experience. Food is not only nourishment and entertainment but also helps travelers understand the people, traditions, and culture of a particular country. However, communication gaps and lack of information make it very challenging for travelers to experience truly local cuisine and the restaurants that serve it.
The Argon Laser and Its Application in Neurological Surgery

Although the argon (Ar) ion laser has been available for many years and has been widely used in ophthalmology and dermatology, its use in neurological surgery has been limited. The recent availabihty of high powered Ar lasers that can rapidly vaporize tissue, transmit light through fiberoptic delivery systems, and have variable and small spot diameters has allowed us to use the laser beneficially for a variety of neurosurgical procedures.
Measurements of maize root plasticity under water stress in hydroponic chambers

Under water stress, plants adjust root traits including depth of root system, root diameter, density of root per volume of soil, hydraulic conductance of root. In this experimental study, we present a method to quantify how hydraulic traits of maize roots adapt to drought. The experiments involve a microfluidic flow sensor and a custom-built pressure chamber, made of transparent plastic for visualization purposes. We measured how maize genotypes (PHB47 and PHZ51) grown for a week in deionized (DI) water and one day in hydroponic nutrients solution (called the irrigated condition) respond to one week of water stress. Conditions of water stress (called drought conditions) were created by mixing Polyethylene Glycol with the nutrients solution. Results show that under drought, the roots of both genotypes respond by approximately halving their global hydraulic conductance. This adjustment seems to be achieved mainly by reductions of the total surface area of the roots. Interestingly, the measured hydraulic conductivity of the roots grown under drought was significantly larger. In all, this study sheds light on how plants adapt to water stress in a hydroponic system, by decreasing root area and increasing root permeability.
Alternative Assumptions to Identify LATE in Fuzzy Regression Discontinuity Designs

There exist two alternative assumptions to identify local average treatment effects (LATE) in fuzzy regression discontinuity (RD) designs: local independence (LI) and local smoothness (LS). Together with the usual LATE assumptions requiring existence of a first‐stage and treatment monotonicity, either of these two assumptions is sufficient to identify RD LATE. I discuss the practical (and testable) implications of these alternative assumptions, and show that weakening LI by LS might be empirically relevant. However, when LI does hold, there are some practical implications one may explore. Numerical and empirical examples are briefly presented.
Cyber alarm: Determining the impacts of hotel's data breach messages

Abstract Since cyber-attacks have become a significant concern in the hospitality industry, hospitality professionals need to address vulnerabilities and capabilities when data breaches take effect at hospitality organizations. This study investigated: (1) how a hotel data breach incident from different information channels influence consumers’ perceptions, and (2) how a hotel’s responsibility for a data breach crisis influence consumers’ revisit intention and trust toward the hotel. The present study employed Situational Crisis Communication Theory to develop a 2 by 2 experimental design research. Participants were randomly assigned into one of four conditions (data breach messages received from either the news or the hotel; whether or not hotel guests are the victim of the incident). This study addresses the impacts of cyber-crisis communication on hospitality organizations. The results provide insights regarding hotel guests’ reactions toward information security and the practical implications for hotel management regarding corporate communication and reputation.
MT1-MMP Binds Membranes by Opposite Tips of Its beta Propeller to Position It for Pericellular Proteolysis.

Summary Critical to migration of tumor cells and endothelial cells is the proteolytic attack of membrane type 1 matrix metalloproteinase (MT1-MMP) upon collagen, growth factors, and receptors at cell surfaces. Lipid bilayer interactions of the substrate-binding hemopexin-like (HPX) domain of MT1-MMP were investigated by paramagnetic nuclear magnetic resonance relaxation enhancements (PREs), fluorescence, and mutagenesis. The HPX domain binds bilayers by blades II and IV on opposite sides of its β propeller fold. The EPGYPK sequence protruding from both blades inserts among phospholipid head groups in PRE-restrained molecular dynamics simulations. Bilayer binding to either blade II or IV exposes the CD44 binding site in blade I. Bilayer association with blade IV allows the collagen triple helix to bind without obstruction. Indeed, vesicles enhance proteolysis of collagen triple-helical substrates by the ectodomain of MT1-MMP. Hypothesized side-by-side MT1-MMP homodimerization would allow binding of bilayers, collagen, CD44, and head-to-tail oligomerization.
Long-Term Hemodynamic Effects After Carotid Artery Revascularization:

Objective:The baroreceptor at the carotid body plays an important role in hemodynamic autoregulation. Manipulation of the baroreceptor during carotid endarterectomy (CEA) or radial force from carot...
Deep Learning for Distortion Prediction in Laser-Based Additive Manufacturing using Big Data

Abstract Laser-Based Additive Manufacturing (LBAM) is a fabrication process that is a key aspect of Industry 4.0, which aims to employ many sensors for continuous process control. One current challenge in LBAM is the geometric inaccuracy of fabricated parts. To increase accuracy, accurate predictions of distortion are needed. Here we develop a novel Deep Learning approach that accurately predicts distortion well within LBAM tolerance limits by considering the local heat transfer for pointwise distortion prediction. Our Deep Learning approach not only gives highly accurate predictions but also fits into the Industry 4.0 framework of analyzing big data with many sensors.
Newer-generation Metallic Stents: Design, Performance Characteristics, and Outcomes

Several new coronary stents have been, or soon will be, introduced in the United States. These stents incorporate certain characteristics, such as polymer-free drug coatings, ultrathin stent struts, bioresorbable polymers, and composite materials, that address currently unmet clinical needs to enhance acute stent performance, improve longer-term clinical outcomes, and obviate obligatory prolonged dual antiplatelet therapy. This article reviews the key and novel features of these stents.
Abstract 124: Radiotracer Imaging of Serial Changes in Angiosome Foot Perfusion in Critical Limb Ischemia Patients Undergoing Lower Extremity Revascularization: Association With 12-month Limb Salvage Outcomes

Introduction: Single photon emission computed tomography (SPECT)/CT imaging is a standard approach for assessing myocardial perfusion, but has not been traditionally applied for evaluating peripher...
Engineering Bone-Implant Materials.

This special issue is dedicated to the simulation as well as experimental studies of biomechanical behavior of biomaterials, especially those that are used for bone implant applications [...]
Excited-State Dipole Moments of Homoleptic [Ru(bpy') 3 ] 2+ Complexes Measured by Stark Spectroscopy.

The visible absorption and Stark spectra of five [Ru(4,4′-(R)2-2,2′-bipyridine)3](PF6)2 and [Ru(bipyrazine)3](PF6)2 complexes, where R = CH3O–, tert-butyl–, CH3–, H–, or CF3–, were obtained in buty...
Numerical modeling of submerged mussel longlines with protective sleeves

Abstract Farmers growing mussels in offshore environments have turned to submerged longline farming as a relatively safe, reliable and profitable way to produce mussels in the exposed ocean environment. However, variations in the environmental conditions (strong currents and storms) and potential presence of predator species (e.g. eider ducks) require robust engineering approaches to design longline mussel farms and their components. This paper describes application of a mechanistic fluid-structure interaction modeling software Hydro-FE to predict the dynamic response of several mooring/longline/dropper configurations subjected to typical and extreme environmental conditions of a North Atlantic mussel farming site. Hydro-FE is a software tool that expands and modernizes the approach previously implemented in the finite element program Aqua-FE developed at the University of New Hampshire to analyze flexible structures in marine environment. The numerical model takes into account smooth variation of the hydrodynamic forces around the free surface (continuous partial submergence), Reynolds number dependence of drag coefficients of mooring lines and includes contributions of predator-protection sleeves to the overall mechanical response of mussel droppers. The simulations provide estimates of anchor forces, mooring line tensions, and time-series data on the motion of the droppers. This information can be used in the design of mussel longlines to prevent anchor failure, rope breakage, line entanglement and mussel fall-off.
Commentary: underutilization of curative-intent therapy for patients with muscle-invasive bladder cancer in Sweden mimics the United States

Patients with muscle-invasive bladder cancer (MIBC) have a narrow window of cure that requires aggressive treatment in order to attempt to achieve cure. Guidelines recommend the use of curative intent therapy (CIT) involving radical cystectomy (RC) with pelvic lymph node dissection and neoadjuvant chemotherapy for those eligible for cisplatin. Alternative treatments, such as partial cystectomy or chemoradiation, are indicated for patients who are medically unfit for RC, for patients who decline RC, or in select patients with favorable tumors who desire bladder preservation (1,2).
“We Are Our Own Counselor”: Resilience, Risk Behaviors, and Mental Health Service Utilization among Young African American Men

Despite risk for trauma, subsequent mental health concerns, and poor health outcomes, young Black/African American men (YBM) are less likely to receive mental health services than other racial/ethn...
Magnetized decaying turbulence in the weakly compressible Taylor-Green vortex.

Magnetohydrodynamic (MHD) turbulence affects both terrestrial and astrophysical plasmas. The properties of magnetized turbulence must be better understood to more accurately characterize these systems. This work presents ideal MHD simulations of the compressible Taylor-Green vortex under a range of initial subsonic Mach numbers and magnetic field strengths. We find that regardless of the initial field strength, the magnetic energy becomes dominant over the kinetic energy on all scales after at most several dynamical times. The spectral indices of the kinetic and magnetic energy spectra become shallower than ${k}^{\ensuremath{-}5/3}$ over time and generally fluctuate. Using a shell-to-shell energy transfer analysis framework, we find that the magnetic fields facilitate a significant amount of the energy flux and that the kinetic energy cascade is suppressed. Moreover, we observe nonlocal energy transfer from the large-scale kinetic energy to intermediate and small-scale magnetic energy via magnetic tension. We conclude that even in intermittently or singularly driven weakly magnetized systems, the dynamical effects of magnetic fields cannot be neglected.
Neuro-Ophthalmic Trauma

This chapter covers traumatic damage to the optic nerve, visual pathways, and oculomotor system. It reviews the relevant anatomy, clinical features, diagnostic workup, and management of traumatic optic neuropathy and acquired Horner syndrome with direct application to the pediatric patient population. The authors highlight the range of ophthalmic manifestations that may follow head trauma, including injury associated with skull base fractures, arterial or venous injury, and traumatic brain injury. Finally, the authors describe the oculomotor system and how to diagnose and manage traumatic injury of cranial nerve (CN) III, IV, or VI. The material will enable the clinician to recognize neuro-ophthalmic manifestations of eye and head trauma, promptly diagnose, and efficiently manage these patients in the acute setting.
Rejoinder to “A Tuning-Free Robust and Efficient Approach to High-Dimensional Regression”

We heartily thank the editors, Professors Regina Liu and Hongyu Zhao, for featuring this article and organizing stimulating discussions. We are grateful for the feedback on our work from the three ...
Negative regulation of FOXP3 expression by c-Rel O-GlcNAcylation.

O-GlcNAcylation is a reversible posttranslational protein modification that regulates fundamental cellular processes including immune responses and autoimmunity. Previously, we showed that hyperglycemia increases O-GlcNAcylation of the transcription factor, Nuclear Factor kappaB (NF-κB) c-Rel at serine residue 350 and enhances the transcription of the c-Rel-dependent proautoimmune cytokines interleukin-2 (IL-2), interferon gamma (IFNG), and granulocyte macrophage colony stimulating factor (GM-CSF) in T cells. c-Rel also plays a critical role in the transcriptional regulation of forkhead box P3 (FOXP3), the master transcription factor that governs development and function of Treg cells. Here we show that the regulatory effect of c-Rel O-GlcNAcylation is gene-dependent, and in contrast to its role in enhancing the expression of proautoimmune cytokines, it suppresses the expression of FOXP3. Hyperglycemia-induced O-GlcNAcylation-dependent suppression of FOXP3 expression was found in vivo in two mouse models of autoimmune diabetes; streptozotocin (STZ)-induced diabetes and spontaneous diabetes in non-obese diabetic (NOD) mice. Mechanistically, we show that both hyperglycemia-induced and chemically enhanced cellular O-GlcNAcylation decreases c-Rel binding at the FOXP3 promoter and negatively regulates FOXP3 expression. Mutation of the O-GlcNAcylation site in c-Rel, (serine 350 to alanine), augments T cell receptor-induced FOXP3 expression and resists the O-GlcNAcylation-dependent repression of FOXP3 expression. This study reveals c-Rel S350 O-GlcNAcylation as a novel molecular mechanism inversely regulating immunosuppressive FOXP3 expression and proautoimmune gene expression in autoimmune diabetes with potential therapeutic implications.
More Lasting than the Effects Achieved by a Gun: The Cinematic Architecture of Lebbeus Woods

This paper examines Lebbeus Woods’ 1988 project “Underground Berlin” and a corresponding film script coauthored by Woods, in an exploration into affinities between cinematic thinking and architectu...
The Seeds and Fruits of English Pre-Raphaelitism: Ford Madox Brown as Teacher and Student

The influence of Ford Madox Brown on the Pre-Raphaelite Brotherhood (PRB) -- both as a mentor and teach to Dante Gabriel Rossetti and as a public supporter of the PRB's project -- is well-known. Less known is the influence that the PRB exerted on Brown's artistic aesthetic and work. Brown's early sketches for "The Seeds and Fruits of English Poetry" -- a monumental work that was never completed -- serve as a welcome reminder of this long and mutually beneficial relationship.
How to Build a Persuasive Web Application

Successful web applications are able to influence the behaviors of their users. The top 40 facebook applications were analyzed to determine the most persuasive ways of achieving such influence. This paper presents a framework of feedback loops for this purpose and then applies it within the context of facebook.
Isolation of Antigens of Pasteurella pestis I. Lipopolysaccharide-Protein Complex and R and S Antigens.

Abstract Larrabee, Allan R. (Fort Detrick, Frederick, Md.), John D. Marshall, and Dan Crozier. Isolation of antigens of Pasteurella pestis. I. Lipopolysaccharide-protein complex and R and S antigens. J. Bacteriol. 90:116–119. 1965.—Pasteurella pestis contains at least 18 different antigens, 2 of which will protect experimental animals from challenge infection. A specific polysaccharide isolated and described as a hapten was isolated as a complete antigen. Two additional antigens were isolated from P. pestis. The preparation of antisera directed against these three antigens and the content of protein, lipid, and carbohydrate of each preparation were studied. None of the preparations will protect mice from challenge infection with virulent P. pestis. A basis for naming the new antigens which does not conflict with previously published designations is presented.
Red Blood Cell Storage

Blood transfusion has played an important role in military casualty care since World War I. In November 1917, Capt. Oswald H. Robertson of the Harvard Medical Unit in Camier, France, took 22 quart bottles of universal donor red blood cells (RBCs) suspended in citrate and glucose to a British Casualty Clearing Station behind the Western Front during the Battle of Cambrai. There he demonstrated for the first time the ability of stored blood to resuscitate soldiers in profound shock and to save lives (1,2). Today, packed RBCs are the most important blood product for combat casualty care (3). They are part of every major military deployment.
Procedures and Practice before the California State Water Rights Board

A reorganization of the powers, duties, and responsibilities of various governmental agencies of the state having functions relating to water was accomplished at a special meeting of the California legislature which convened concurrently with the 1956 budget session. By chapter 52 of that special session the offices of the then Division of Water Resources, of the Department of Public Works, and its chief, the State Engineer, were abolished, but their functions were preserved and divided between a newlycreated Department of Water Resources' and a independent three-member board, denominated the State Water Rights Board.2 One of these members is required to be an attorney and another an engineer.3 All are appointed at large by the Governor,' but are removable only for cause by a majority of the members elected to each house of the legislature.5 The Governor also designates a member to serve at his pleasure as Chairman.6 All hearings and meetings of the Board are required to be open to the public.7 A major function of the Board is the administration of the statutory law relating to the appropriation of the unappropriated, or unused, water of the state. The practice and procedure of the Board in the administration of t ese statutes is the subject of the discussion which follows. This function has an extensive legislative history, beginning December 19, 1914.8 The present statutes concerning it are found in Division 2, Part 2, of the Water Code. These are extensive, comprising 158 sections,9 and are supplemented by a 34-page printed pamphlet"' containing detailed rules and regulations formulated over the 43-year period since the function was first authorized by the legislature. This pamphlet also contains eight pages of general information concerning water rig ts. This informative publication is freely available to all. To secure a copy one need only write the Board at its Sacramento office, requesting a copy of its current rules and regula-