cssi/SciSciGPT-SciSciNet huggingface dataset:
Solid-phase epitaxial growth of Ge layers

Epitaxial growth of a semiconductor from a solid phase solution is demonstrated. Ge layers were grown from a solid solution of Ge in an Al film onto n-type Ge substrates. Electrical measurements showed the resultant layers to be heavily p-doped. Channeling effect measurements with MeV 4He+ ions indicate that the layers are well-ordered and epitaxial. Es wird das epitaktische Wachstum von Halbleitern aus einer festen Losung nachgewiesen. Ge-Schichten wuchsen aus einer festen Losung von Ge in einem Al-Film auf n-leiten-den Ge-Substraten. Elektrische Messungen zeigten, das die resultierenden Schichten stark p-dotiert sind. Kanal-Effekt-Messungen mit MeV 4He+-Ionen zeigten, das die Schichten epitaktisch und gut geordnet sind.
The (Twice) Failure of the Wisconsin Risk Need Assessment in a Sample of Probationers

Despite being created and validated in the 1970s and 1980s, and widely adopted by many agencies in the United States, including Texas, the Wisconsin Risk Need Assessment Instrument has yet to be examined with a contemporaneous Texas probationer sample. Due to the majority of previous research reporting poor utility, the instrument’s authors proposed a new scoring system for the risk portion of the instrument in 2009 in an attempt to increase the predictive utility. This study examines the original instrument and is the first to examine the proposed reweighted risk scale’s relationship to recidivism with an independent sample of 194 male probationers. Findings revealed that the original risk/need sections and proposed reweighted risk items failed to explain significant variance in recidivism with very few items relating to reoffense. The current results provide further evidence that the Wisconsin Risk Need Assessment should be replaced by other empirically validated risk/need instruments.
Disorders of the pathways involved in the creative process

Abstract The apparent contradiction between the frequent incidence of affective disorders among highly creative people and studies that support significantly positive correlations between creative abilities and ego strength can be accounted for by distinguishing between the form and essence of the creative act. Creative potential is universal. All creative acts entail disrupting an existing homeostatic structure and subsequently synthesizing a new, more adaptive one. This cycle is a necessary part of the healthy response to stressful events. Thus, certain psychiatric illnesses can be reformulated as being disorders of psychobiological mechanisms underlying the creative process, a viewpoint that offers substantial benefits to psychotherapeutic efforts.
Effects of sulfur dioxide and formaldehyde on particle clearance in the rat

The effects of exposures to sulfur dioxide and formaldehyde atmospheres on the clearance of inhaled, insoluble tracer particles from the lungs of rats have been studied. The tracer particles employed were polystyrene latex microspheres radio-labeled with 51Cr. Following the deposition of the 1.9-micron activity median aerodynamic diameter (AMAD) particles, the rats were divided into 3 groups for a single 4-h exposure to purified air, 20 ppm sulfur dioxide, or 20 ppm formaldehyde. Early, presumably upper-respiratory-tract, clearance was monitored by analysis of radioactivity excreted in feces, while late, presumably deep-lung, clearance was followed by thoracic counting of the animals. Both the sulfur dioxide and formaldehyde atmospheres did significantly delay early clearance (p less than 0.1, two-tailed t-test). However, the late clearance rates of the two pollutant-exposed groups of rats were not significantly different from that of the purified air-exposed group of rats. Although sulfur dioxide had numerically greater effects than formaldehyde, the differences were not statistically significant at the p less than 0.1 level.
PACs, lobbies and political conflict: The case of gun control

Previous research has shown that PAC contributions from the National Rifle Association as well as letters and lobbying by Handgun Control, Inc. significantly affected Congressional voting on the Firearms Owners Protection Act of 1986, holding constant ideology, party, constituency characteristics, and a proxy for prior position on the issue. Using data from that study, this paper shows that contributions have a somewhat different effect than lobbying. Contributions from NRA were primarily targeted at NRA supporters and had the net effect of making the progunners even more so. Contributions from Handgun Control, while they did not significantly reinforce the proclivities of the gun controllers, were directed only at that group. At least in this case, money appears to exacerbate conflict. By contrast, the police lobby directed its attention at both gun controllers and pro-gunners; the lobby effectively induced pro-gunners to moderate their position.
Literature and poetry

Beyond the Culture Tours: Studies in Teaching and Learning With Culturally Diverse Texts. Gladys Cruz, Sarah Jordan, Jose Melendez, Steven Ostrowski, and Alan Purves, Mahwah, NJ: Lawrence Erlbaum Associates, Inc., 1997, 108 pages, $16.00. ISBN 0–8058–2613–0. Bilingual Education: From Compensatory to Quality Schooling. Maria Estela Brisk, Mahwah, NJ: Lawrence Erlbaum Associates, Inc., 1998, 206 pages, $29.95 (soft‐cover). Transforming the Curriculum for Multicultural Understanding: A Practitioner's Handbook. James B. Boyer and H. Prentice Baptiste, Jr., San Francisco: Caddo Gap, 1996, 266 pages, $19.95. ISBN 1–8801–9219–5. Standing Outside on the Inside: Black Adolescents and the Construction of Academic Identity. Olga M. Welch and Carolyn R. Hodges, Albany, NY: State University of New York Press, 1997, 144 pages, $14.95. ISBN 0–7914–3342–0. Social and Emotional Adjustment and Family Relations in Ethnic Minority Families. Ronald W. Taylor and Margaret C. Wang (Eds.), Mahwah, NJ: Lawrence Erlbaum Associates...
Confirmation of molecular markers and agronomic traits associated with seed phytate content in two soybean RIL populations.

The concentration of phytate is an important consideration when analyzing feed grain for livestock. Simple sequence repeat markers Satt237 and Satt561 were found to be linked to quantitative trait loci (QTLs) for phytate con- centration in soybean (Glycine max (L.) Merr.) seed. Previous research also established a signifi cant correlation between seed inorganic phosphorus (Pi) and seed phytate. The objec- tives of this study were to confi rm these QTL in independent environments and populations, to compare the effectiveness of marker-assisted selection with that of phenotypic selection for low phytate, and to evaluate agronomic traits associated with low phytate soybean. The low phytate soybean mutant CX1834-1-2 was crossed with the cultivar 5601T and line S97- 1688 to form two populations. The Satt237 marker was linked to a major QTL (R 2 > 0.10) governing seed phytate, and Satt561 was linked to a minor QTL (R 2 < 0.10) in both populations. These two confi rmed QTL have been named cqPha-001 and cqPha-002. The phenotypic correlations were signifi cant (P < 0.05) for plant height (r = 0.26), seed protein (r = −0.19), and seed oil (r = 0.17). Phenotypic selection was found to be more effective in lowering mean phytate levels and more cost effi cient.
Evaporative instability in pulsed laser-heated droplets.

First observations of an evaporative instability in absorptive dye (Nigrosin) doped water droplets heated by a pulsed Nd:YAlG laser (532 nm) are reported. Measurement of the instability thresholds at different dye concentrations shows an approximate inverse linear dependence on droplet absorption index, suggesting that the instability is caused by superheating of the droplet. The instability may trigger subsequent droplet deformation or or disintegration; however, below a well-defined fluence threshold, complete recovery of the droplet occurs following laser excitation. A qualitative model based on Landau instability theory is used to describe the instability.
Crystalline polyimides containing 4,4′‐bis(3,4‐dicarboxyphenoxy)‐diphenyl sulfide dianhydride

A high degree of crystallinity has been found in unoriented polymer films formed from 4,4'-bis(3,4-dicarboxyphenoxy)diphenyl sulfide dianhydride (BDSDA) and p-phenylenediamine (PDA). Partial crystallinity for a polymer containing BDSDA and benzidine is also reported. A study of the thermal properties of the crystalline polyimides shows crystalline melting points of 426 C and 483 C respectively for the BDSDA-PDA and the BDSDA-benzidine polymers.
Anomalous dispersion effects in low-pressure atomic-iodine lasers at 1.315 μm

The atomic-iodine hyperfine structure is shown to produce anomalous dispersion effects on its hyperfine laser transition at 1.315 μm whenever reasonable small-signal gains are available (~1% cm). This dispersion effect is linearly dependent on the iodine inversion density. Such an anomalous dispersion effect may produce strong phase-induced mode–media interactions for all the lower-gain iodine hyperfine transitions in any low pressure (<50 Torr) atomic-iodine laser. Fortunately, the highest-gain hyperfine transition, F′ = 3 → F″ = 4, has the smallest amount of additional phase shift (or refractivity) introduced by this anomalous dispersion. All the other transitions experience much larger anomalous dispersion effects. This condition should act as an internal frequency discriminator, forcing the iodine to lase on the highest-gain hyperfine transition.
Interaction of thiamine and pyridoxine in Neurospora. I. Studies of the pyridoxineless mutants.

Abstract All pyridoxineless mutants of Neurospora crassa and Neurospora sitophila grow better if thiamine is also added to the culture medium. On the basis of the evidence which includes ( a ) an analysis of the growth curves; ( b ) the requirement for thiamine at various concentrations of pyridoxine; ( c ) the interrelation of vitamins B 6 , B 1 , and time; and ( d ) assay of the mycelial content of B 6 and B 1 ; it is concluded that B 1 competitively inhibits the destruction of B 6 . B 6 in turn interferes with thiamine biosynthesis, but sufficient endogenous B 1 is present to satisfy normal metabolic requirements, at least so far as growth is concerned. A specific mechanism is suggested which will be further developed in later publications.
Simulation of neural nets with some applications to visual information processing

Abstract Since the utility of modeling is contingent upon the facility with which successful predictions may be obtained, the application of machine computation to a broad class of models is clearly advantageous. The following points are introduced to elaborate this philosophy. The plausibility arguments for the use of the Rashevsky two-factor neutral elements and computational forms (a nonlinear set of first-order differential equations) are presented. The details of an analog-computer simulation of twelve neural elements are explained as are the capabilities of the inputs, the outputs, and the interconnections which are used to form neural nets. On, off, and on-off behavior of neural pathways are simulated with “on,” “off” and “on-off” elements and predictions are made about the relative amplitudes of the response of the pathways as the stimulating pulse-width decreases. The phenomena of visual masking are described and the model of Landahl is presented. The details of the simulation of visual masking, including the use of iterated computation to model the entire experimental procedure as well as the response of the observer to a single trial, are illustrated. The agreement of the behavior of the model (as found by N. Weisstein) with five diverse sets of data is explained.
Librarian vs. (Open Access) Predator: An Interview with Jeffrey Beall

In February 2013, Kristen Wilson interviewed Jeffrey Beall, scholarly initiatives librarian at the University of Colorado Denver. Beall discusses “predatory” open access and its implications for scholarly publishing.
Thinning, stacking, and TSV proximity effects for Poly and High-K/Metal Gate CMOS devices in an advanced 3D integration process

An advanced 3D integration process featuring through silicon via (TSV) and chip-on-wafer (CoW) technologies has been demonstrated. Using this 3D process, Poly and High-K/Metal Gate (HKMG) CMOS wafers have been successfully thinned and stacked, showing little to no degradation in the process. The effect of TSV induced mechanical stress on ΔIdsat for HKMG is found to be smaller as compared to Poly Gate devices for the same channel length (ΔIdsat ratio of HKMG to Poly is ∼0.3 and ∼0.5 for PMOS and NMOS, respectively). In addition, we show that ΔIdsat for HKMG device is proportional to TSV diameter square, independent of TSV orientation, device polarity, and device distance from TSV.
Rabaptin-5 is a novel fusion partner to platelet-derived growth factor β receptor in chronic myelomonocytic leukemia

Chromosomal translocations involving the platelet-derived growth factor beta receptor (PDGFbetaR) gene have been reported in some patients with chronic myelomonocytic leukemia (CMML). The resultant fusion proteins have constitutive PDGFbetaR tyrosine kinase activity, but the partner genes previously reported (tel, Huntingtin interacting protein 1 [HIP-1], H4/D10S170) have poorly understood roles in the oncogenic activity of the fusion proteins. A novel PDGFbetaR fusion protein has been characterized in a patient with CMML and an acquired t(5;17)(q33;p13). Southern blot analysis on patient leukemia cells demonstrated involvement of the PDGFbetaR gene. Using 5' rapid amplification of complementary DNA ends-polymerase chain reaction (RACE-PCR) on patient RNA, rabaptin-5 was identified as a novel partner fused in-frame to the PDGFbetaR gene. The new fusion protein includes more than 85% of the native Rabaptin-5 fused to the transmembrane and intracellular tyrosine kinase domains of the PDGFbetaR. Transduction with a retroviral vector expressing rabaptin-5/PDGFbetaR transformed the hematopoietic cell line Ba/F3 to growth factor independence and caused a fatal myeloproliferative disease in mice. Rabaptin-5 is a well-studied protein shown to be an essential and rate-limiting component of early endosomal fusion through interaction with the Ras family GTPases Rab5 and Rab4. The fusion protein includes 3 of 4 coiled-coil domains (involved in homodimerization of native rabaptin-5), 2 caspase-3 cleavage sites, and a binding site for the tumor suppressor gene tuberin (tuberous sclerosis complex-2). Early endosomal transport is critical in regulation of various growth factor receptors, through ligand-induced clathrin-mediated endocytosis, and thus this new fusion protein links together 2 important pathways of growth regulation.
Head and Neck Cancer in the Older Adult: Approaches in Evaluation and Management

Head and neck cancer collectively represents a growing cancer diagnosis among older adults. Many insights have been gained into the pathogenesis and risk factors of head and neck cancer. Moreover, major improvements have occurred in surgical approaches, the delivery of chemotherapy and radiation therapy, and the management of their complications for head and neck cancer. However, how these cancer therapies are best applied to older adults with head/neck cancer remains unclear and under-studied. This review will serve to synthesize the current data available in evaluating and managing head and neck cancer with a focus on the older adult; unique issues and knowledge gaps in geriatric oncology as they apply to those with head/neck cancer, while raising survivorship issues that are key in this growing patient population.
Vasopressin-reversible increase in angiotensin-converting enzyme in specific hypothalamic nuclei of Brattleboro rats

Abstract The activity of the angiotensin-converting enzyme (ACE) (kininase II, EC 3.4.15.1) was examined in 5 discrete hypothalamic nuclei of rats lacking vasopressin (homozygous Brattleboro rats, DI, di/di)and their corresponding controls (heterozygous Brattleboro rats, HZ, di/+, and Long Evans, LE, +/+ rats), with and without hormonal replacement with arginine-vasopressin (AVP). DI rats showed a vasopressin-reversible increased ACE activity when compared with LE controls, HZ rats showing intermediate activity. These changes occurred only in the supraoptic and periventricular hypothalamic nuclei, and were absent in other hypothalamic areas studied, including the paraventricular nucleus. These results provide biochemical evidence in support of previous anatomical and physiological data, for an interaction between the brain vasopressin and angiotensin systems in discrete hypothalamic nuclei, and suggest that vasopressin could regulate the formation of brain angiotensin II by modulating the activity of the converting enzyme.
Survey of dynamic computational general equilibrium models for tax policy evaluation

Abstract Perhaps the most active area of research in the field of computable general equilibrium tax models involves the addition of genuine dynamics to the behavior of both consumers and producers. Such model enhancement in the direction of dynamics is necessary to satisfactorily capture the effects of such tax alternatives as the adoption of an expenditure tax or the integration of the corporate and personal tax systems. This paper surveys 11 models that include at least some dynamics in their structure. It treats the issue of incorporating dynamics into the models, and also discusses different computational and implementation approaches. Finally, it includes a dynamic computational general equilibrium model of corporate tax integration that indicates the potential importance of modeling dynamic choice.
THE GENUS AMYLOMYCES

SUMMARY Amylomyces is a monotypic genus containing the somewhat variable species A. rouxii Calmette. Certain species of Chlamydomucor and Boedijn's species Rhizopus chlamydosporus are synonyms. Strains vary from somewhat restricted sterile white colonies to light gray-brown colonies containing many abortive sporangia. All strains produce abundant chlamydospores. During growth in liquid media containing glucose as the carbon source, the glucose is exhausted during the first 3 da and lactic acid is formed that is used as a secondary carbon source after a short lag period. The pattern of utilization of sucrose, maltose, and glycerol by strains of Amylomyces rouxii and Rhizopus oryzae supports the morphological data that make these two genera distinct. An unique fungus has often been isolated from ragi and Chinese yeast. Both are used as starters to make fermented foods in Indonesia and elsewhere in the Orient. The main ingredient of ragi is rice flour. This fermented starter contains both yeasts and molds (9). Chinese yeast is a similar product. The predominant mold in these two starters is a member of the Mucorales that is propagated primarily by chlamydospores. At most, isolates form abortive sporangia. Although various names have been proposed for this fungus, its correct name is Amylomyces rouxii Calmette.
Denitrification potential of soils from constructed and natural wetlands

Laboratory experiments were conducted to determine the NO3− removal (reduction) potential of wetland soils currently used for the disposal of reclaimed wastewater. Surface soil samples were collected, incubated under anoxic conditions with two levels of NO3−, and the evolution of N2O was measured with time. Denitrification rates ranged from 0.06 to 0.92 g N m−2 day−1, when 10 mg NO3-N per kg oil was added. Complete reduction of NO3− to N2 occurred in the soils collected from two constructed wetlands (mineral soils) and one natural wetland (organic soil). However, the final reduction step was inhibited in the soils collected from two wetlands with organic soils. The inhibition was most likely the result of the lower pH of these soils. The results suggest that the addition of wastewater enhances the potential for denitrification in these soils.
Transient states in reaction centers containing reduced bacteriopheophytin

Photosynthetic reaction centers isolated from Rhodopseudomonas sphaeroides strain R-26 were excited with non-saturating 7-ps, 600-nm flashes under various conditions, and the resulting absorbance changes were measured. If the quinone electron acceptor (Q) is in the oxidized state, flash excitation generates a transient state (PF), in which an electron has moved from the primary electron donor (P, a dimer of bacteriochlorophylls) to an acceptor complex involving a special bacteriopheophytin (H) and another bacteriochlorophyll (B). PF decays in 200 ps as an electron moves from H to Q and the acceptor complex are reduced photochemically before the excitation, the flash generates a different transient state of P with a high quantum yield. This state decays with a lifetime of 340 ps. There is no indication of electron transfer from P to B under these conditions, but this does not rule out the possibility that B is an intermediate electron carrier between P and H. Measurements of the yield of fluorescence from P under various conditions show that the 340 ps state is not the fluorescent excited singlet state of P. The transient state could be a triplet state, a charge-transfer state of P, or another excited singlet state that is not fluorescent.
Mesenchymal stem cell implantation in a swine myocardial infarct model: engraftment and functional effects.

Abstract Background . A novel therapeutic option for the treatment of acute myocardial infarction involves the use of mesenchymal stem cells (MSCs). The purpose of this study was to investigate whether implantation of autologous MSCs results in sustained engraftment, myogenic differentiation, and improved cardiac function in a swine myocardial infarct model. Methods . MSCs were isolated and expanded from bone marrow aspirates of 14 domestic swine. A 60-minute left anterior descending artery occlusion was used to produce anterior wall infarction. Piezoelectric crystals were placed within the ischemic region for measurement of regional wall thickness and contractile function. Two weeks later animals autologous, Di-I–labeled MSCs (6 × 10 7 ) were implanted into the infarct by direct injection. Hemodynamic and functional measurements were obtained weekly until the time of sacrifice. Immunohistochemistry was used to assess MSC engraftment and myogenic differentiation. Results . Microscopic analysis showed robust engraftment of MSCs in all treated animals. Expression of muscle-specific proteins was seen as early as 2 weeks and could be identified in all animals at sacrifice. The degree of contractile dysfunction was significantly attenuated at 4 weeks in animals implanted with MSCs (5.4% ± 2.2% versus −3.37% ± 2.7% in control). In addition, the extent of wall thinning after myocardial infarction was markedly reduced in treated animals. Conclusions . Mesenchymal stem cells are capable of engraftment in host myocardium, demonstrate expression of muscle specific proteins, and may attenuate contractile dysfunction and pathologic thinning in this model of left ventricular wall infarction. MSC cardiomyoplasty may have significant clinical potential in attenuating the pathology associated with myocardial infarction.
Timeliness of interfacility transfer for ED patients with ST-elevation myocardial infarction ☆

Abstract Objectives Most US hospitals lack primary percutaneous coronary intervention (PCI) capabilities to treat patients with ST-elevation myocardial infarction (STEMI) necessitating transfer to PCI-capable centers. Transferred patients rarely meet the 120-minute benchmark for timely reperfusion, and referring emergency departments (EDs) are a major source of preventable delays. We sought to use more granular data at transferring EDs to describe the variability in length of stay at referring EDs. Methods We retrospectively analyzed a secondary data set used for quality improvement for patients with STEMI transferred to a single PCI center between 2008 and 2012. We conducted a descriptive analysis of the total time spent at each referring ED (door-in–door-out [DIDO] interval), periods that comprised DIDO (door to electrocardiogram [EKG], EKG-to-PCI activation, and PCI activation to exit), and the relationship of each period with overall time to reperfusion (medical contact-to-balloon [MCTB] interval). Results We identified 41 EDs that transferred 620 patients between 2008 and 2012. Median MCTB was 135 minutes (interquartile range [IQR] 114,172). Median overall ED DIDO was 74 minutes (IQR 56,103) and was composed of door to EKG, 5 minutes (IQR 2,11); EKG-to-PCI activation, 18 minutes (IQR 7,37); and PCI activation to exit, 44 minutes (IQR 34,56). Door-in door-out accounted for the largest proportion (60%) of overall MCTB and had the largest variability (coefficient of variability, 1.37) of these intervals. Conclusions In this cohort of transferring EDs, we found high variability and substantial delays after EKG performance for patients with STEMI. Factors influencing ED decision making and transportation coordination after PCI activation are a potential target for intervention to improve the timeliness of reperfusion in patients with STEMI.
Effects of Limited Suckling and Varying Prepartum Nutrition on Postpartum Reproductive Traits of Milked Buffaloes

Abstract Effects of supplemental prepartum feeding and limited suckling on postpartum reproductive performance of milked Nili-Ravi water buffaloes were examined in two 2×2 factorial experiments. Prepartum feeding was either moderate (metabolizable energy=32 Mcal/d) or high (46 Mcal/d) in Experiment 1 and high (46 Mcal/d) or very high (51 Mcal/ d) in Experiment 2. Nutritional treatment was initiated about 75 d prior to calving and stopped at parturition. Half of the buffaloes were suckled by their calves twice daily (2min at each milking) until second estrus. Prepartum feeding did not influence any trait measured in either experiment. Postpartum intervals to uterine involution, resumption of follicular development, first rise in milk progesterone, first palpable corpus luteum, and first estrus were longer for limited-suckled buffaloes than for those that were only milked. Most buffaloes (86%) showed at least one short luteal phase (8 to 13 d) before first estrus. Number of rises of progesterone before first estrus was greater for limited-suckled buffaloes in Experiment 2 but not in Experiment 1. Luteal activity after first estrus (15 to 19 d) and pregnancy rate to insemination at second estrus (average 50%) did not differ with limited suckling. In conclusion, postpartum anestrus of water buffaloes can be shortened by weaning calves at birth, regardless of supplemental feeding prepartum.
Oxygen pressures over fast breeder reactor fuel (I) A model for UO2±x☆

Abstract A model has been developed for calculating oxygen pressures for uranium oxide compositions in the range from the UO 2−x metal-rich boundary to UO2,1. The model is based on the law of mass action, the free energy of formation of UO2 and U4O9, and phase boundary data. Oxygen pressures calculated with the model are in excellent agreement with experimental observations.
Portopulmonary hypertension: Evolving concepts and therapy

0 rthotopic liver transplantation has become an accepted therapy For end stage liver disease. As centers become increasingly sophisticated and experienced in the perioperative care of the liver disease patient, historic contraindications lo candidacy are being challenged. One such contraindication is the presence of combined portal and pulmonary hypertension, so-called portopulmonaty hypertension. With improved methods of preoperative diagnosis, new pharmacologic therapies, advances in anesthesia and critical care, and accrual of clinical experience, this condition no longer is an absolute contraindication to liver transplantation. Recent data suggest that patients with certain clegrees ~Tportopulrnonaty hypertension can undergo liver transplantation with acceptable morbidity and mortality. The purpose of this review is to provide an update on the evolving thoughts regarding the cause, pathophysiology, pathology, and clinical parameters associated with portopulmonaty h~pcrtension.
Multiway analysis of epilepsy tensors

Motivation: The success or failure of an epilepsy surgery depends greatly on the localization of epileptic focus (origin of a seizure). We address the problem of identification of a seizure origin through an analysis of ictal electroencephalogram (EEG), which is proven to be an effective standard in epileptic focus localization. Summary: With a goal of developing an automated and robust way of visual analysis of large amounts of EEG data, we propose a novel approach based on multiway models to study epilepsy seizure structure. Our contributions are 3-fold. First, we construct an Epilepsy Tensor with three modes, i.e. time samples, scales and electrodes, through wavelet analysis of multi-channel ictal EEG. Second, we demonstrate that multiway analysis techniques, in particular parallel factor analysis (PARAFAC), provide promising results in modeling the complex structure of an epilepsy seizure, localizing a seizure origin and extracting artifacts. Third, we introduce an approach for removing artifacts using multilinear subspace analysis and discuss its merits and drawbacks. Results: Ictal EEG analysis of 10 seizures from 7 patients are included in this study. Our results for 8 seizures match with clinical observations in terms of seizure origin and extracted artifacts. On the other hand, for 2 of the seizures, seizure localization is not achieved using an initial trial of PARAFAC modeling. In these cases, first, we apply an artifact removal method and subsequently apply the PARAFAC model on the epilepsy tensor from which potential artifacts have been removed. This method successfully identifies the seizure origin in both cases. Contact: [email protected]
Humanists as Teachers of Science

culture, then surely science and its role in present and past societies must be part of it (Winchester 1989, iii). Furthermore, as I argue in this essay, at a time when the gap between the "two cultures" of the sci entist and of the humanist is increasing at a dizzying rate, the need has become pressing for nonscientists to play a greater role in teaching science in their liberal arts courses. I find it difficult to disagree with the sentiments of the engineer Henry Petros ki (1984): "If a true liberal education means understanding the world in which one lives, then engineering, computer sci ence, and applied mathematics courses should certainly be required for a degree" (14). For how can there be profitable philosophical or religious discussions of birth control or abortion without an understanding of biology? Can we mean ingfully study the aesthetics of art with out an understanding of sensory mecha nisms or, on the other hand, the actual
THE EFFECT OF THIOURACIL ON THE COLLECTION OF RADIOACTIVE IODINE BY THE THYROID OF THE CHICK

WE HAVE previously found (Larson, Keating, Peacock and Rawson, 1945) that the thyroid of the chick made goitrous by the administration of thiouracil in the drinking water had a diminished capacity to collect injected radioactive iodine. This effect was present only while thiouracil was being given; when the drug was withdrawn, the goitrous thyroids rapidly acquired a capacity to collect radioactive iodine in quantities even larger than controls. Rawson, Tannheimer and Peacock (1944) have observed in the rat that goiters produced by the administration of thiouracil collectedless radioactive iodine than did controls, whereas thyroid made goitrous by the administration of potassium thiocyanate collected a largei proportion of the injected dose than did controls. Franklin, Lerner and Chaikoff (1944) have made the same observation. In in vitro experiments by Franklin and Chaikoff (1943) and by Schachner, Franklin and Chaikoff (1944) it was found that sulfanilamide inhibited the formation of thyroxin and diiodo...
Acute and Sustained Release of the Atrial Natriuretic Factor Prohormone N-Terminus with Acute Myocardial Infarction

This investigation was designed to determine if acute ischemic cardiac injury causes the release of the 98 amino acid (aa) N-terminus of the 126 aa atrial natriuretic factor prohormone (pro ANF). Seventeen patients with acute myocardial infarction, but without clinical evidence of congestive heart failure, had their circulating concentrations of the whole N-terminus (ie, pro ANF 1-98), the midportion of the N-terminus of the ANF prohormone (consisting of aa 31-67; pro ANF 31-67) and creatine phosphokinase (CPK) monitored daily for 14 days. All seventeen patients had elevated plasma pro ANF 1-98 and pro ANF 31-67 concentrations at the time of presentation. Maximal increase on day three post-infarction correlated with the size of infarction estimated by the maximal CPK (r = 0.675; p less than 0.05) but did not correlate with the amount of left ventricular dysfunction. Another three patients with acute myocardial infarction were treated with tissue plasminogen activator (tPA). The measured pro ANF 1-98 and pro ANF 31-67 levels in these patients were within our normal range and significantly lower (p less than 0.001) than seen in patients with acute myocardial infarction not given thrombolytic therapy. Six patients with unstable angina, likewise, had normal circulating pro ANFs 1-98 and 31-67 concentrations during prolonged episodes of chest pain. These data suggest that myocardial necrosis but not ischemia triggers the release of the entire 126 aa prohormone.
Determination of trazodone and its metabolite, 1-m-chlorophenyl-piperazine, in human plasma and red blood cell samples by HPLC.

Abstract Objectives: To develop an HPLC method for the analysis of trazodone and its metabolite, 1-m-chlorophenyl-piperazine (m-CPP), in human plasma and red blood cells. Design and Methods: The analytes were extracted by heptane containing 1.5% isoamyl alcohol, back extracted into phosphoric acid and analyzed by reverse phase HPLC with UV detection. Results: In seven randomly selected, male, human subjects plasma concentrations (nmol/I) were 380–5841 for trazodone and 14–237 for m-CPP while those in packed red blood cells were 98–634 for trazodone and 15–155 for m-CPP. Plasma trazodone concentrations were 4–11-fold higher than those in red blood cells while those of m-CPP were about equal. This may be the first report on concentrations of trazodone and m-CPP in human red blood cells. This sensitive method can be used for monitoring trazodone and m-CPP in human plasma and red blood cells.
Copper and zinc in the amniotic fluid and serum from high-risk pregnant women.

SummaryCopper was found to be a normal constituent of the amniotic fluid in high-risk pregnant women at the level of 0.14 ± 0.004 ppm (n = 138). Copper in the amniotic fluid was positively correlated (P < 0.001) to maternal serum copper levels at r = 0.43. During the 13-19 weeks of early pregnancy, copper levels in the amniotic fluid and serum were not appreciably influenced by gestational age. There was no significant correlation between copper and zinc in serum or amniotic fluid. Copper levels in serum and amniotic fluid during this period were not altered in pregnant women having an increased risk of producing a child with a fetal anomaly.
Deterioration of a Classical Final-Stage Microstructure: A Study in Alumina

Classical final-stage microstructures have been obtained in an ultra-high-purity alumina by a latex sphere impregnation and burnout technique. The isolated equilibrium-shaped pores produced by the latex spheres deteriorated during long-term, high-temperature annealing under reducing atmospheres to produce a cracklike interconnected pore network. Several mechanisms of degradation are considered, including (i) the influence of entrapped gases, (ii) the effect of stresses produced during differential sintering, and (iii) the kinetics of competing mass transport mechanisms. Results suggest that the degradation is an inherent microstructural instability promoted by enhancing the ratio of coarsening rate/densification rate. Furthermore, it is shown that magnesia additions inhibit the process of microstructural deterioration.
Subsea downhole optical sensing

The potential for subsea downhole optical fibre sensing to optimize hydrocarbon production and hence contribute to enhanced oil recovery is described. The components of susbea downhole optical sensing systems are reviewed and the performance of a new subsea optical fibre feed-through for downhole optical fibre sensing reported.
6.2: Mechanical Properties of Jade™ Glass Substrate for LTPS Application

Mechanical properties of Jade™ glass substrate, including ring-on-ring strength of surfaces, vertical bend strength of ground edges, dynamic fatigue constant, fracture toughness, and Young's modulus, are presented. This high strain point glass is designed to meet low compaction requirement for low temperature polysilicon process (LTPS). Its fusion surface quality ensures pristine surfaces with high strength. Its superior edge finish leads to high edge strength. Its composition and manufacturing process eliminate the need for post-forming thermal treatment. Its intrinsic thermal stability minimizes viscous distortion during LTPS processing. Its fracture toughness is similar to that of a-Si glasses, yet its fatigue resistance is superior due, primarily, to its composition.
NUMERICAL SIMULATION OF THE EFFECT OF SPATIAL DISTURBANCES ON VORTEX ASYMMETRY

The steady asymmetric vortex pattern observed on slender bodies of revolution at large angle of attack was investigated using fine-grid Navier-Stokes computations. The computed results demonstrate the marked asymmetry which has been observed in experiments. To obtain asymmetry, it was found essential to introduce a space-fixed time-invariant perturbation into the computation. The computational results suggest that vortex asymmetry is forced by amplification of small disturbances, such as those due to surface roughness, occurring within the body viscous boundary layer.
Detection of Water Pollutants by Laser Excited Resonance Raman Spectroscopy; Pesticides and Fungicides

The feasibility of resonance Raman spectroscopy in the detection of hazardous chemicals in water has been tested on some nitrophenol-based pesticides and fungicides. In most cases, detection limits below the parts per million level were obtained. The method was also tested on an artifically polluted river water sample.
Evaluation of a Computer-Based Administration of the Rey Complex Figure Test

This study examined the equivalence of a graphics tablet-based computer administration of the Rey Complex Figure Test (RCF) with a traditional paper-and-pencil administration of the RCF. Participants were also assessed for computer anxiety, attitudes, and familiarity, as well as comfort with the computer equipment used in the study. Sixty-two undergraduate volunteers completed the RCF using the computer graphics tablet and an alternate form of the test (Taylor Complex Figure; TCF) using pencil and paper. RCF and TCF copies were independently scored by two pairs of scorers. No significant performance differences were observed in the first scoring pair; however, participants scored significantly higher on their paper-and-pencil reproduction than on their tablet reproduction in the second pair. No significant relationships between computer-based RCF performance and preexisting computer attitudes, anxiety, or familiarity were found. Participants' ratings suggested that the graphics tablet was perceived as interesting but more difficult to use than the paper-and-pencil administration method. Despite the potential administration and scoring advantages of a computer graphics tablet-based administration, results did not support tablet use as an alternate administration method for the RCF.
Review: Cholinesterase inhibitors do not prevent dementia in patients with mild cognitive impairment

Source Citation Cooper C, Li R, Lyketsos C, Livingston G. Treatment for mild cognitive impairment: systematic review. Br J Psychiatry. 2013;203:255-64. 24085737
A critical examination of some newly available standards for liquid scintillation counting.

Abstract Some newly available encapsulated sources of carbon-14 and tritium have been evaluated for their usefulness as accurate, convenient internal standards in liquid scintillation counting. They have been found to be as accurate and reproducible as claimed and provide the practitioner with a clean, rapid method for using the widely applicable internal standard method. The water-soluble tritium standard (sucrose) requires a minimum water concentration (1.3% for Aquasol-2) in a detergent cocktail before it will completely dissolve. Efficiency determination of colored and gelled samples is considerably simplified as is the preparation of quenched standard sets in any cocktail system.
Novel Docosanoids Inhibit Brain Ischemia-Reperfusion-mediated Leukocyte Infiltration and Pro-inflammatory Gene Expression

Ischemic stroke triggers lipid peroxidation and neuronal injury. Docosahexaenoic acid released from membrane phospholipids during brain ischemia is a major source of lipid peroxides. Leukocyte infiltration and pro-inflammatory gene expression also contribute to stroke damage. In this study using lipidomic analysis, we have identified stereospecific messengers from docosahexaenoate-oxygenation pathways in a mouse stroke model. Aspirin, widely used to prevent cerebrovascular disease, activates an additional pathway, which includes the 17R-resolvins. The newly discovered brain messenger 10,17S-docosatriene potently inhibited leukocyte infiltration, NFκB, and cyclooxygenase-2 induction in experimental stroke and elicited neuroprotection. In addition, in neural cells in culture, this lipid messenger also inhibited both interleukin 1-β-induced NFκB activation and cyclooxygenase-2 expression. Thus, the specific novel bioactive docosanoids generated in vivo counteract leukocyte-mediated injury as well as pro-inflammatory gene induction. These results challenge the view that docosahexaenoate only participates in brain damage and demonstrate that this fatty acid is also the endogenous precursor to a neuroprotective signaling response to ischemia-reperfusion.
Twitteracy: Tweeting as a New Literacy Practice

Abstract This article defines Twitter tm ; outlines the features, affordances, and common uses; and conceptualizes “tweeting” as a literacy practice, comprising both traditional and new literacies, and impacting both informal and formal learning settings. Also provided is an overview of traditional and new literacies, and insights from a scan of the research literature to date on tweeting as a literacy practice. The authors outline areas for inquiry and the challenges to conducting such research.
Real-time Daily Activity Classification with Wireless Sensor Networks using Hidden Markov Model

This paper presents a hidden Markov model (HMM) approach for real-time activity classification using signals from wearable wireless sensor networks. A wearable wireless sensor network can be used to continuously monitor the daily activities of a subject in real time. However, the wireless sensor nodes are constrained by limited battery and computing resources. The proposed HMM framework has been applied to find the most probable activity states series with low data transmission rate, which makes it highly suitable for daily activity classification applications. The performance was evaluated using a small sensor network consisting of three accelerometers. The activity detection rate is 95.82%, using a test set of 5 subjects with 11 activity series.
Clarifying the Preschool Assessment Process: Traditional Practices and Alternative Approaches

Preschool assessment is a complex process through which children's eligibility for special education services is determined. The assessment process requires decisions based on information gathered at several steps. To make these decisions, teams of professionals and families require information gathered from multiple sources. This article provides an overview of traditional and nontraditional sources of assessment information.
Classical and quantum phase space evolution: fixed-lattice and trajectory solutions

Abstract Recently, a new trajectory method for advancing solutions of evolutionary partial differential equations was proposed: the derivative propagation method (DPM) evolves the solution and its spatial derivatives concurrently and eliminates the need for function fitting, finite-differences (FDs), etc. This trajectory method and a stationary lattice FD algorithm are applied in phase space to solve the classical Klein–Kramers and quantum modified Caldeira–Leggett equations for several examples: a double-well oscillator in contact with a thermal bath and the decay of a metastable state. For the latter potential, the trajectory and fixed-grid solutions are compared and any discrepancies are noted.
On the role of anxiety in decisions under possibilistic uncertainty

We focus on situations in which we must decide on what time to take an action. The action is not in question it is the time of action. We call these "time for action decisions," a prototypical example being deciding when to leave on a journey. We point out that during this type of decision process, the decision-maker recognizes two groups of forces acting on him: one that pushes him to act now and other that pushes him act later. We note that the strength of these forces depends on the information available about various uncertainties associated with the situation. It also strongly depends upon the personality of the decision-maker. We observe that as time passes these conflicting forces tend to build up an anxiety in the decision-maker resulting in an action being taken at a time of most intense anxiety. In this paper using the ideas of possibility and necessity measures to enable different interpretations of uncertain information we investigate the temporal profile of the decision-maker's anxiety as a function of their decision attitude. We investigate the role of maximization of anxiety as decision paradigm. One of our goals here is to try to understand role of the nature and the quality information plays in these types of decisions as well as its interaction with anxiety.
Emotional category data on images from the International Affective Picture System.

The International Affective Picture System (IAPS) is widely used in studies of emotion and has been characterized primarily along the dimensions of valence, arousal, and dominance. Even though research has shown that the IAPS is useful in the study of discrete emotions, the categorical structure of the IAPS has not been characterized thoroughly. The purpose of the present project was to collect descriptive emotional category data on subsets of the IAPS in an effort to identify images that elicit one discrete emotion more than others. These data reveal multiple emotional categories for the images and indicate that this image set has great potential in the investigation of discrete emotions. This article makes these data available to researchers with such interests. Data for all the pictures are archived at www .psychonomic.org/archive/.
Innovations in Treating the Elderly Who Have Biliary and Pancreatic Disease

Many diseases of the biliary tract and pancreas preferentially effect the elderly. Recent innovations in the evaluation and management of these disorders have directly impacted the lives of many seniors. Improved outcomes of pancreatic surgery is a good example of a positive impact in quality of life, especially when these surgeries are performed in centers of excellence. Evaluation and treatment strategies are presented for complicated calculous biliary disease, pancreatic carcinoma, and pancreatic cystic neoplasms.