cssi/SciSciGPT-SciSciNet huggingface dataset:
Adolescent Neurodevelopment and Psychopathology

Adolescence is a high-risk period for the onset of psychopathology. The occurrence of depression increases markedly in the years following the onset of puberty, and most individuals who are eventually diagnosed with a psychotic disorder show a marked rise in adjustment problems during adolescence. It is well established that puberty involves increases in the secretion of gonadal hormones. More recently, research has shown that stress hormones show a similar normative rise following puberty. Accumulating findings indicate that the postpubescent period is also characterized by significant neurodevelopment; there are changes in brain structure and function that are partially a consequence of hormonal factors. Researchers are now challenged to elucidate the neural mechanisms relating postpubertal neurodevelopment with the elevations in risk for psychopathology that characterize adolescence. One plausible mechanism is the effect of hormones on gene expression. The normal neuromaturational processes observed in...
Networking behaviors and career outcomes: differences for men and women?

Summary Engaging in networking behaviors, by attempting to develop and maintain relationships with others who have the potential to provide work or career assistance, is considered to be an important career management strategy. This study explores the relationship between networking behavior and career outcomes (i.e., number of promotions, total compensation, perceived career success) in a sample of managerial and professional employees. Furthermore, we investigate whether networking behavior is as beneficial for women as it is for men. Results indicated that some types of networking behavior were related to both objective and perceived career outcomes. In addition, gender differences do impact the utility of networking behavior as a career-enhancing strategy. Explanations of our results and implications for engaging in networking behavior are discussed. Copyright # 2004 John Wiley & Sons, Ltd.
Correlation of leaf chlorophyll readings and stem nitrate concentrations in peppermint

Abstract The SPAD chlorophyll meter appears promising for rapid, on‐farm analysis of crop nitrogen (N) status. Leaf SPAD chlorophyll levels have been correlated with total leaf N concentrations, but it has not been determined how they relate to other widely applied N diagnoses such as petiole or stem nitrate (NO3) analysis. Our objective was to examine the relationship between leaf SPAD readings and stem NO3 levels in peppermint (Mentha piperita L.). Upper canopy SPAD chlorophyll and stem NO3 concentrations were determined weekly during two seasons for peppermint grown with variable N inputs. Leaf SPAD levels exhibited significant linear‐plateau responses with respect to stem NO3, indicating that SPAD readings do not respond to luxury N consumption. The meter is therefore promising for the detection of crop N deficiencies by comparison of production fields to well fertilized plots or strips. Break‐points in the linear‐plateau regressions describe saturation concentrations of stem NO3 with respect to leaf ...
Identification of Osteopontin as a Novel Ligand for the Integrin α8β1 and Potential Roles for This Integrin–Ligand Interaction in Kidney Morphogenesis

Epithelio‐mesenchymal interactions during kidney organogenesis are disrupted in integrin a8b1-deficient mice. However, the known ligands for integrin a8b1—fibronectin, vitronectin, and tenascin-C—are not appropriately localized to mediate all a8b1 functions in the kidney. Using a method of general utility for determining the distribution of unknown integrin ligands in situ and biochemical characterization of these ligands, we identified osteopontin (OPN) as a ligand for a8b1. We have coexpressed the extracellular domains of the mouse a8 and b1 integrin subunits as a soluble heterodimer with one subunit fused to alkaline phosphatase (AP) and have used the a8b1-AP chimera as a histochemical reagent on sections of mouse embryos. Ligand localization with a8b1-AP in developing bone and kidney was observed to be overlapping with the distribution of OPN. In “far Western” blots of mouse embryonic protein extracts, bands were detected with sizes corresponding to fibronectin, vitronectin, and unknown proteins, one of which was identical to the size of OPN. In a solid-phase binding assay we demonstrated that purified OPN binds specifically to a8b1-AP. Cell adhesion assays using K562 cells expressing a8b1 were used to confirm this result. Together with a recent report that anti-OPN antibodies disrupt kidney morphogenesis, our results suggest that interactions between OPN and integrin a8b1 may help regulate kidney development and other morphogenetic processes.
Corporate Restructurings: A Comparison of Equity Carve-outs and Spin-offs

In this paper we examine divisive corporate restructurings in which a firm takes a subsidiary public. Using a sample of 64 spin-off and 76 carve-out firms during 1991–1997, we find firms carve-out subsidiaries with higher market demand. These subsidiaries are more frequently in related industries than spin-offs. The carve-out firms are also more likely to be cash constrained and have lower marginal tax rates, but are not likely to be considering financial reporting synergies when structuring the divestiture. These results provide evidence that factors impacting the divestiture choice related to Master Limited partnerships, as studied previously, differ when divesting a corporate subsidiary.
Automated Design of Spacecraft Telecommunication Subsystems Using Evolutionary Computational Techniques

This paper discusses the application of evolutionary computing to a dynamic space vehicle telecommunication subsystem resource and performance simulation in a parallel processing environment. Our objective is to demonstrate the feasibility, application and advantage of using evolutionary computation techniques for the early design search and optimization of space systems. With this approach, engineers specify several sets of conditional subsystem performance criteria to trade off subsystem goals of mass, cost, performance and risk. Once specified, the integrated evolutionary/simulation software will then automatically generate a design option for each criteria, selecting and sizing telecom elements based on the space system's anticipated performance in the simulated environment. Initial activity plans from an actual JPL mission, Deep Impact (DI) are used to test the software. Our results have shown human-competitive advantages by generating credible design concepts much faster than humans are able to and without the need for expert initial designs.
Distribution of calmodulin and calmodulin‐binding proteins in membranes from bovine epididymal spermatozoa

Reproducible concentrations of calmodulin representing approximately 0.1% of the membrane protein were detected in purified plasma membranes from bovine epididymal spermatozoa. When membranes were isolated in the presence of 1 mM EGTA, the amount of calmodulin associated with the plasma membranes was not reduced. Calmodulin-binding proteins were detected in both purified plasma membranes and in a mixed membrane fraction containing both plasma membranes and cytoplasmic droplet membranes. A calcium-dependent, calmodulin-binding protein of apparent molecular weight 123,000 was detected in both fractions. In the presence of 1 mM EDTA, putative calcium-independent calmodulin-binding proteins of apparent molecular weights 93,000, 32,000, 18,000, and 15,000 were detected in the plasma membrane fraction. The 15,000 Mr polypeptide was also present in the mixed membrane fraction but the three proteins of higher molecular weight were reduced or absent in this fraction.
Concentration theorem for tripartite LDPC codes

This paper presents the framework of tripartite LDPC codes and more than a single coded bit affects its channel outputs. Symbol-nodes along with variable-nodes and check-nodes of the graph of an LDPC codes is used to represent a third set of nodes in channel output. Thus the concentration theorem is considered in this framework, which optimizes the average performance of the codes and the design criterion is meaningful for a randomly chosen sample from the ensemble of LDPC codes.
Research highlights: aptamers on a chip

Aptamers, oligonucleic acid or peptide molecules with binding affinity to a specific molecule, have gained broad scientific attention due to their stability, ease of production and modification, and durability, and therefore have been employed in a wide range of applications both in basic research and clinical science. Recent advances in high-throughput sequencing are poised to revolutionize the selection of aptamers, while microfluidic and microarray approaches have helped automate these processes of selection. Here we highlight work addressing several challenges in using aptamers more widely. We discuss array-based discovery of multivalent aptamers which is used to develop high affinity or paired aptamers by cleverly selecting new aptamers that bind to previously aptamer-bound proteins. Other highlighted work is addressing problems in analyzing local cell secretions, as well as refreshable sensors that detect signals over hundreds of cycles and can be refreshed with DI water scavenged from the air, leading to less reagent storage towards wearable sensors.
Reducing Atomic Force Microscope Tip Deflection using Command Shaping

Dynamic atomic force microscopy (AFM) is a popular scanning method that utilizes an oscillating cantilever tip to interact with and develop high resolution images of surfaces. Though this method is one of the most versatile in AFM, it is dependent upon maintaining constant oscillation amplitude. Constant oscillation amplitude can be difficult to achieve when probe movement is necessary to maintain an appropriate tip to sample distance. This paper documents the effectiveness of command shaping techniques in reducing the probe's tip deflection during the scanning process. Command shapers are used to modify the movements of the scanning probe base in response to changes in the sample's surface. Reducing tip deflection and tip tracking error improve the quality of the scanned image while reducing the likelihood of damage to the sample or the probe.
Small scale energy harvesting - principles, practices and future trends

Harvesting small scale energy from otherwise wasted ambient energy sources has attracted immense research efforts for battery-powered wireless sensor networks for various applications such as structural health monitoring, industrial condition monitoring and healthcare. The power level which those applications may reach ranges from microwatts to milliwatts. Energy scavenged from ambient sources may be able to recharge or even eliminate the battery to power up those devices perpetually. Sources of energy for harvesting include, but are not limited, to light, thermal gradient, vibration, and radio frequency radiation. The fluctuation and intermittence of these ambient energy sources bring in challenging technical issues to make self-powered systems practical. Energy storage devices like rechargeable batteries or supercapacitors and efficient power management circuitry are indispensable to convert a dynamic environmental energy input into a stable power source. This presentation reviews principles of energy harvesting and practices for small scale energy harvesters and self-powered wireless sensor modules developed recently. Industry trends and possible research issues for further developments are discussed in order to give a technical insight into energy harvesting techniques and their applications.
Asymmetric interjoint feedback contributes to postural control of redundant multi-link systems

Maintaining the postural configuration of a limb such as an arm or leg is a fundamental neural control task that involves the coordination of multiple linked body segments. Biological systems are known to use a complex network of inter- and intra-joint feedback mechanisms arising from muscles, spinal reflexes and higher neuronal structures to stabilize the limbs. While previous work has shown that a small amount of asymmetric heterogenic feedback contributes to the behavior of these systems, a satisfactory functional explanation for this non-conservative feedback structure has not been put forth. We hypothesized that an asymmetric multi-joint control strategy would confer both an energetic and stability advantage in maintaining endpoint position of a kinematically redundant system. We tested this hypothesis by using optimal control models incorporating symmetric versus asymmetric feedback with the goal of maintaining the endpoint location of a kinematically redundant, planar limb. Asymmetric feedback improved endpoint control performance of the limb by 16%, reduced energetic cost by 21% and increased interjoint coordination by 40% compared to the symmetric feedback system. The overall effect of the asymmetry was that proximal joint motion resulted in greater torque generation at distal joints than vice versa. The asymmetric organization is consistent with heterogenic stretch reflex gains measured experimentally. We conclude that asymmetric feedback has a functionally relevant role in coordinating redundant degrees of freedom to maintain the position of the hand or foot.
Low threshold InGaAs-AlGaAs-GaAs strained-layer quantum well heterostructure square ring lasers

We have described a monolithically integrated strained-layer InGaAs SCH square ring laser using narrow grooves to couple out light from the ring resonator to the straight output waveguides and demonstrated the asymmetry of two lasing modes from two output waveguides of different lengths in the emission spectra as well as in the output powers. >
Experience sampling mood and its correlates at work

The experience sampling method is used to measure variance over time in events, moods, and behaviours in the work setting via palmtop computers in a sample of 41 employees. Theoretical propositions about event-mood-behaviour relations are derived from Affective Events Theory (Weiss & Cropanzano, 1996) and tested using within- and between-persons variance. The experiment found 56% of the variance in hedonic tone of mood was within- rather than between-persons. Hedonic tone was significantly related to both positive and negative work events in expected directions. The relationship between negative events and mood was approximately five times stronger than that between positive events and mood, even though positive events were reported three to five times more frequently than negative events. Hedonic tone was positively related to engaging in work withdrawal and negatively related to engaging in work tasks. Implications of these findings as well as the use of experience sampling for the study of dynamic workplace variables are discussed.
Are There Linkages Between Different Types of Globalization and Economic Growth

The theoretical and empirical debates on the relationship between globalization and economic growth are still hot, and worth to keep studying on. This paper makes two contributions into the literature. First, although there is a wide array of literature examines the cross-country and panel studies using comprehensive measure of globalization such as KOF index, none of them has solely focused on the causality relationship between different types of globalization and economic growth in Turkey. Second, despite the fact that many papers investigate the linkages between economic growth and single variables of KOF index (i.e. foreign direct investment, and trade openness) in Turkey, none of them has used an advance measurement for globalization. So, the purpose of this study is thus to fulfilling this gap, and to examine the causality connection between economic globalization (ECON), political globalization (POL), social globalization (SOC), and overall globalization (GLOB) and economic growth (GR) in Turkey using econometrics in time-series methods. Findings of this paper exhibit that there are bi-directional causalities between economic globalization, social globalization, and overall globalization and economic growth.
Web-based alcohol prevention for incoming college students: a randomized controlled trial.

article i nfo College students are an at-risk population based on their heavy alcohol consumption and associated consequences. First-year students are at particular risk due to greater freedom and access to alcohol on campus. Web-based (electronic) interventions (e-interventions) are being rapidly adopted as a universal approach to prevent high-risk drinking, but have not been well evaluated. The objective of this study was to investigate the effectiveness of the two most widely adopted EIs, AlcoholEdu and The Alcohol eCHECKUP TO GO (e-Chug), in reducing both alcohol use and alcohol-related consequences in incoming college students. To do so, we conducted a 3-group randomized trial (N=82) comparing AlcoholEdu and e-Chug to an assessment-only control group. Compared to the assessment-only control group, participants in the AlcoholEdu and e-Chug groups reported lower levels of alcohol use across multiple measures at 1-month follow-up. Participants who received AlcoholEdu showed significantly fewer lower alcohol-related consequences than assessment-only controls, while there was a trend for reduced consequences in participants who received e-Chug versus assessment-only. Findings indicate that e-intervention is a promising prevention approach to address the problem of college student alcohol consumption, especially for campuses that have limited resources.
Twin-Screw Extrusion Texturization of Acid and Alkali Denatured Soy Proteins

Effect of pH on functional characteristics of soy protein was investigated by modifying soy flour through acid (HCl) or alkali (NaOH) addition. Acid- and alkali-treated proteins were evaluated and texturized by twin-screw extrusion. Products were analyzed by rheological, functional, and ultrastructural methods. Acid-modified texturized protein had little expansion, increased peak force, increased work of shearing, and a nonoriented fiber arrangement. Slightly alkaline extrudates had increased rehydration but poorer texture. Stronger alkaline treatment resulted in denser products with high peak force measurements, which disintegrated when extrudates were rehydrated. The physicochemical state of soy protein, particularly conformation and protein-water interactions as affected by pH, may influence expansion of textured products and development of plexilamellar structure.
The Screening Test for Emotional Problems--Teacher-Report Version (Step-T): Studies of Reliability and Validity.

The Screening Test for Emotional Problems – Teacher Version (STEP-T) was designed to identify students aged 7–17 years with wide-ranging emotional disturbances. Coefficients alpha and test-retest r...
Justice and Equality: Some Questions About Scope

Can a society be just if it ignores the plight of other societies? Does it matter whether those societies are contemporaries? Moral “purists” are likely to assume that the answer to these questions must be “no.” Relying on familiar claims about impartiality or universalizability, the purist is likely to assert that the dictates of justice have no bounds, that they extend with equal strength across space and time. On this view, if, for example, justice requires us to maximize the expectations of the worst-off group in our society, it also requires us to maximize the expectations of the worst-off group in any society, at any time, so far as it is in our power to do so. Is such a position plausible? Is it more plausible than alternative positions? I am unsure about the answers to these questions, but both the questions, and the answers, are important. Clearly, the nature and extent of a just society's obligations will vary markedly depending on the scope of the correct principles of justice.
Video delivery technologies for large-scale deployment of multimedia applications

Deployment of a large-scale multimedia streaming application requires an enormous amount of server and network resources. The simplest delivery technique allocates server resources for each specific request. This technique is very expensive and is not scalable to support a very large user community such as the Internet. Hence, the past decade has witnessed tremendous research efforts to facilitate cost-effective, large-scale deployment of multimedia streaming applications. In this paper, we describe three complementary research approaches: server transmission schemes using multicast, streaming strategies with application layer multicast, and proxy caching techniques. We discuss pros and cons of these technologies and provide our observations on current business solutions.
PSMA-Based Detection of Prostate Cancer Bone Lesions With 18F-DCFPyL PET/CT: A Sensitive Alternative to 99mTc-MDP Bone Scan and Na18F PET/CT?

Imaging of bone metastases in prostate cancer has traditionally involved planar Tc-methylene diphosphonate (Tc-MDP) bone scan with or without the use of supplemental tomographic imaging. More recently, NaF positron emission tomography/x-ray computed tomography (PET/CT) has been found to have improved sensitivity and specificity for sites of osseous metastatic involvement. Prostate-specific membrane antigen (PSMA) is a cell surface enzyme that is highly expressed in prostate cancer and has been explored as a target for prostate cancer imaging. In this case report, we found that PSMA-based PET/ CT with the small molecule F-DCFPyL detected a large number of bony lesions that were occult on Tc-MDP bone scan and NaF PET/CT. PSMA-targeted PET/CT may offer improved sensitivity by binding directly to tumor cells, as opposed to localizing to sites of bony reaction. This preliminary finding should be further explored in larger studies.
Presentation of the Distinguished Public Service Award for 2013 of the Mineralogical Society of America to Pierrette Tremblay

Mr. President, Members of the Society, and honored guests: It is my honor to present Pierrette Tremblay, the 2013 recipient of the Distinguished Public Service Medal—in recognition of her critical role in the creation and continued success of Elements. With more than 15,200 individual subscriptions and nearly 1000 institutional subscriptions in 105 countries, Pierrette has guided some 329 articles in 52 issues, for a total of more than 3500 pages, through the editorial process and to a five-year impact factor of 3.612. More important than the numbers is the fact that Elements has caused 17 different international societies to work together for the common good of mineralogy, geochemistry, and petrology. Pierrette’s role was essential to every step of creating Elements, and more importantly, she remains the key driving force behind every aspect of the magazine—designing each issue, she handles the editing, advertising, layout, production, …
A Main/standby Mode Based Supplementary Damping Control Strategy of TCSC for Subsynchronous Oscillation

In order to damp subsynchronous oscillation(SSO) completely and reliably,it is necessary to study the active suppressing strategies of TCSC for SSO,which can provide additional guarantee besides the damping effect of TCSC's nature characters.Based on the analysis of the principles of attenuating SSO,a TCSC supplementary damping control for SSO is proposed as an active suppression approach.Using phase compensation principle,the proposed method extracts the subsynchronous components through measuring the remote or local signals and provides supplementary electromagnetic torque for electrical damping when integrated with existing TCSC controls.Considering both damping effect and controller reliability,controls based on remote shaft speed deviation are used as the main and those based on local electrical quantities are treated as standby.A test system is derived from a real system for research purpose.Through small signal stability analysis and time domain simulation,the oscillation variation is compared between cases with and without the TCSC supplementary damping control for SSO.The effect of different control inputs and the standby control is also studied.The results show that based on this control principle,the electrical damping increases using whether remote or local input,and the effect of remote shaft speed deviation is better than that of local active power deviation.
Analysis on Case-finding of Pulmonary Tuberculosis in 2002-2005 in Huoshan County

Objective To analyze case-finding of pulmonary tuberculosis in Huoshan county, to evaluate the impact of implementing the modern tuberculosis control strategy in Huoshan.Method The data from TB quarterly, annual reporting system and other related information during 2002-2005 was collected and analyzed.Results From 2002 to 2005 total activity pulmonary TB cases were 926, Smear positive cases were 477, and the new cases were 315 in smear positive cases. The rate of the pulmonary TB suspects visiting a doctor was raised from 0.95‰ in 2002 to 2.46‰ in 2005.The registration rate of smear positive cases was raised from 17.22/100,000 in 2002 to 51.95/100,000 in 2005.Conclusion The level of case-finding of pulmonary tuberculosis improved in Huoshan for 4 years, and achieved significant achievements, due to the modern tuberculosis control strategy.
Integration of outpatient infectious diseases clinic pharmacy services and specialty pharmacy services for patients with HIV infection.

Purpose The integration of specialty pharmacy services and existing outpatient clinical pharmacy services within an infectious diseases (ID) clinic to optimize the care of patients with human immunodeficiency virus (HIV) infection is described. Summary The management of HIV-infected patients is a highly specialized area of practice, often requiring use of complex medication regimens for reduction of HIV-associated morbidity and mortality prophylaxis and treatment of opportunistic infections, and prevention of HIV transmission. To maximize the effectiveness and safety of treatment with antiretroviral agents and associated pharmacotherapies, an interdisciplinary team is often involved in patient care. At Chicago-based Northwestern Medicine (NM), the outpatient ID clinic has long worked with an interdisciplinary care team including physicians, clinical pharmacists, nurses, and social workers to care for patients with HIV infection. In April 2014, specialty pharmacy services for patients with HIV infection were added to the NM ID clinic’s care model to help maintain continuity of care and enhance patient follow-up. The care model includes well-defined roles for clinical pharmacists, pharmacy residents and students on rotation, and licensed pharmacy technicians. Specialty pharmacy services, including medication education, prescription fulfillment, assistance with medication access (e.g., navigation of financial assistance programs, completion of prior-authorization requests), and treatment monitoring, allow for closed-loop medication management of the HIV-infected patient population. Conclusion Integration of specialty pharmacy services with the interdisciplinary care provided in the outpatient NM ID clinic has enhanced continuity of care for patients with HIV infection in terms of prescription filling, medication counseling, and adherence monitoring.
Renal adenocarcinoma with solitary metastasis to the contralateral adrenal gland: report of 2 cases and review of the literature.

AbstractWe report 2 rare cases of renal adenocarcinoma with solitary metastasis to the contralateral adrenal gland, 1 recognized synchronously with the primary neoplasm and 1 found 15 years after nephrectomy. The latter case represents the longest reported interval between nephrectomy and treatment of a solitary contralateral adrenal metastasis of renal adenocarcinoma. Distinction of these metastatic tumors from primary adrenocortical carcinoma was facilitated by immunohistochemical markers. Twelve other reported cases of renal adenocarcinoma with solitary contralateral adrenal metastasis support aggressive surgical management of this lesion.
A genetic assessment of the English bulldog

This study examines genetic diversity among 102 registered English Bulldogs used for breeding based on maternal and paternal haplotypes, allele frequencies in 33 highly polymorphic short tandem repeat (STR) loci on 25 chromosomes, STR-linked dog leukocyte antigen (DLA) class I and II haplotypes, and the number and size of genome-wide runs of homozygosity (ROH) determined from high density SNP arrays. The objective was to assess whether the breed retains enough genetic diversity to correct the genotypic and phenotypic abnormalities associated with poor health, to allow for the elimination of deleterious recessive mutations, or to make further phenotypic changes in body structure or coat. An additional 37 English bulldogs presented to the UC Davis Veterinary Clinical Services for health problems were also genetically compared with the 102 registered dogs based on the perception that sickly English bulldogs are products of commercial breeders or puppy-mills and genetically different and inferior. Four paternal haplotypes, with one occurring in 93 % of dogs, were identified using six Y-short tandem repeat (STR) markers. Three major and two minor matrilines were identified by mitochondrial D-loop sequencing. Heterozygosity was determined from allele frequencies at genomic loci; the average number of alleles per locus was 6.45, with only 2.7 accounting for a majority of the diversity. However, observed and expected heterozygosity values were nearly identical, indicating that the population as a whole was in Hardy-Weinberg equilibrium (HWE). However, internal relatedness (IR) and adjusted IR (IRVD) values demonstrated that a number of individuals were the offspring of parents that were either more inbred or outbred than the population as a whole. The diversity of DLA class I and II haplotypes was low, with only 11 identified DLA class I and nine class II haplotypes. Forty one percent of the breed shared a single DLA class I and 62 % a single class II haplotype. Nineteen percent of the dogs were homozygous for the dominant DLA class I haplotype and 42 % for the dominant DLA class II haplotype. The extensive loss of genetic diversity is most likely the result of a small founder population and artificial genetic bottlenecks occurring in the past. The prominent phenotypic changes characteristic of the breed have also resulted in numerous large runs of homozygosity (ROH) throughout the genome compared to Standard Poodles, which were phenotypically more similar to indigenous-type dogs. English bulldogs have very low genetic diversity resulting from a small founder population and artificial genetic bottlenecks. Although some phenotypic and genotypic diversity still exists within the breed, whether it is sufficient to use reverse selection to improve health, select against simple recessive deleterious traits, and/or to accommodate further genotypic/phenotypic manipulations without further decreasing existing genetic diversity is questionable.
A super-atomic norm minimization approach to identifying sparse dynamical graphical models

This paper considers the problem of identifying sparse dynamical graphical models from input/output data. Our main result shows that this problem can be recast into an expanded atomic-norm minimization framework that allows for enforcing block-sparsity. This approach leads to efficient algorithms capable of handling large data sets, unknown inputs and fragmented data records. These results are illustrated with several examples.
On Hamilton Cycles in Cayley Ghaphs in Groups with Cyclic Commutator Subgroup

It has been conjectured there is a Hamilton cycle in every Cayley graph in a finite group. We prove this in the case where the commutator subgroup of the group is a cyclic p-group.
The Changing Financial Landscape of Renal Transplant Practice: A National Cohort Analysis

Kidney transplantation has become more resource intensive as recipient complexity has increased and average donor quality has diminished over time. A national retrospective cohort study was performed to assess the impact of kidney donor and recipient characteristics on transplant center cost (exclusive of organ acquisition) and Medicare reimbursement. Data from the national transplant registry, University HealthSystem Consortium hospital costs, and Medicare payments for deceased donor (N = 53 862) and living donor (N = 36 715) transplants from 2002 to 2013 were linked and analyzed using multivariate linear regression modeling. Deceased donor kidney transplant costs were correlated with recipient (Expected Post Transplant Survival Score, degree of allosensitization, obesity, cause of renal failure), donor (age, cause of death, donation after cardiac death, terminal creatinine), and transplant (histocompatibility matching) characteristics. Living donor costs rose sharply with higher degrees of allosensitization, and were also associated with obesity, cause of renal failure, recipient work status, and 0-ABDR mismatching. Analysis of Medicare payments for a subsample of 24 809 transplants demonstrated minimal correlation with patient and donor characteristics. In conclusion, the complexity in the landscape of kidney transplantation increases center costs, posing financial disincentives that may reduce organ utilization and limit access for higher-risk populations.
ATP-Dependent Formation of Free Synaptic Vesicles from PC12 Membranes in Vitro*

Synaptic vesicles are released from membranes during incubation at 37°C in the presence of ATP (adenosine triphosphate). The donor membranes are a rapidly sedimenting fraction derived from the neuroendocrine cell line PC12 (pheochromocytoma 12). These starting membranes contain the synaptic vesicle proteins, synaptophysin and SV2, and the endosomal markers transferrin receptor and cation-independent MPR (mannose 6-phosphate receptor). Incubating the membranes in vitro increased the amount of organelles that migrate as synaptic vesicles in velocity sedimentation gradients. The synaptic vesicle fractions that contain both synaptophysin and SV2 do not contain endosomal markers. A synaptic vesicle increase in vitro is time-, cytosol-, ATP- and temperature-dependent and is inhibited by NEM (N-ethylmaleimide), BFA (brefeldin A) and aluminum fluoride, but not GTPγS (guanosine-5′-O-C3-thiotriphosphate). The production of synaptic vesicles under these conditions is unlike the de novo generation of vesicles from endosomes (1). Incubation in vitro under the conditions described here may allow the final stages of synaptic vesicle formation, uncoating or undocking, to occur but not the initiation of formation de novo.
5-FU/leucovorin, irinotecan, oxaliplatin (FOLFIRINOX) induction followed by chemoXRT in borderline resectable pancreatic cancer.

e14613 Background: FOLFIRINOX improves overall survival compared to gemcitabine in patients with metastatic PCa. We retrospectively evaluated the feasibility of using induction FOLFIRINOX followed ...
Search for new physics with tau final states at 13 TeV

Abstract Searches for four new particles: Sequential Standard Model W' and Z' bosons, right-handed W bosons and third-generation leptoquarks; are performed using pp collision data at s = 13 TeV recorded by the CMS detector at the LHC. The events observed are found to be in good agreement with the SM predictions. At 95% confidence level, new mass exclusions are set for W'SSM between 1 to 3.3 TeV, for Z'SSM up to 2.1 TeV, for WR up to 3.2 TeV, when the N τ mass is half the mass of WR, and for third-generation leptoquarks up to 900 GeV.
An Energy-Efficient Programmable Manycore Accelerator for Personalized Biomedical Applications

Wearable personalized health monitoring systems can offer a cost-effective solution for human health care. These systems must constantly monitor patients’ physiological signals and provide highly accurate, and quick processing and delivery of the vast amount of data within a limited power and area footprint. These personalized biomedical applications require sampling and processing multiple streams of physiological signals with a varying number of channels and sampling rates. The processing typically consists of feature extraction, data fusion, and classification stages that require a large number of digital signal processing (DSP) and machine learning (ML) kernels. In response to these requirements, in this paper, a tiny, energy-efficient, and domain-specific manycore accelerator referred to as power-efficient nanoclusters (PENC) is proposed to map and execute the kernels of these applications. Simulation results show that the PENC is able to reduce energy consumption by up to 80% and 25% for DSP and ML kernels, respectively, when optimally parallelized. In addition, we fully implemented three compute-intensive personalized biomedical applications, namely, multichannel seizure detection, multiphysiological stress detection, and standalone tongue drive system (sTDS), to evaluate the proposed manycore performance relative to commodity embedded CPU, graphical processing unit (GPU), and field-programmable gate array (FPGA)-based implementations. For these three case studies, the energy consumption and the performance of the proposed PENC manycore, when acting as an accelerator along with an Intel Atom processor as a host, are compared with the existing commercial off-the-shelf general-purpose, customizable, and programmable embedded platforms, including Intel Atom, Xilinx Artix-7 FPGA, and NVIDIA TK1 advanced RISC machine -A15 and K1 GPU system on a chip. For these applications, the PENC manycore is able to significantly improve throughput and energy efficiency by up to $1872{\times}$ and $276{\times} $ , respectively. For the most computational intensive application of seizure detection, the PENC manycore is able to achieve a throughput of 15.22 giga-operations-per-second (GOPs), which is a $14{\times} $ improvement in throughput over custom FPGA solution. For stress detection, the PENC achieves a throughput of 21.36 GOPs and an energy efficiency of 4.23 GOP/J, which is $14.87{\times} $ and $2.28{\times} $ better over FPGA implementation, respectively. For the sTDS application, the PENC improves a throughput by $5.45{\times} $ and an energy efficiency by $2.37{\times} $ over FPGA implementation.
The Stone Surgeon/Lithotomists’ Armamentarium: Today and Tomorrow

Advancements over the past three decades in endourological instrumentation have transformed the stone surgeon’s armamentarium. This chapter reviews the most significant recent advancements and commonly used tools for conducting ureteroscopy and percutaneous nephrolithotomy. Based on in vitro and clinical studies, we provide a comparative assessment of numerous devices, including properties and critical design characteristics that support improved functionality and outcomes. Additionally, we focus on changing trends and clinical challenges associated with medical devices used for treating stone disease.
A compensated voltage-mode control strategy for a DC-DC boost converter in a solar battery charger

In this paper, the analysis and design of a switch-mode DC-DC boost converter with a feedback control for a solar battery charging circuit are presented. The design of a feedback control for such converters is desired to ensure an output with zero steady state error and fast response to input/output voltage and load changes. To achieve these characteristics, a fixed frequency compensated voltage-mode controller is designed and implemented for a DC-DC boost converter operating in Continuous Conduction Mode (CCM). The proposed controller addresses the issue of moving Right-Half-Plane (RHP) zero of a boost converter caused by variations in the input voltage of solar panel and load. The designed controller is fast, robust, and does not have the complexity of current available strategies for battery charging circuits. The simulation studies are provided to evaluate the performance of the proposed approach.
Long-Term Results of Internal Thoracic Artery Grafting

After nearly four decades of coronary artery bypass surgery, internal thoracic artery grafts have proven to be the best conduit for revascularization. They are resistant to arteriosclerosis and have excellent and stable long-term patency. Use of the left internal thoracic artery to revascularize the left anterior descending improves both long-term survival and freedom from cardiac events. The survival benefit of internal thoracic artery grafting increases with time, and patient-related factors, such as age, gender, and left ventricular dysfunction, do not decrease this benefit. Internal thoracic artery grafting of the left anterior descending should be an integral part of nearly all surgical coronary revascularizations.
Quasi-Classical use of Trace Identities in one and Higher Dimensional Field Theories

Suppose one suspected that a non-linear system in 1+1 dimensions was perfect (completely integrable)1, but did not know all the classical static or time-dependent solutions. If one wished to consider such a system as a field theory and apply functional WKB methods2 to compute quasi-classical quantities, it is generally assumed that one would have to know all these solutions to the original nonlinear system. The reason is that they determine the saddle point of the functional integral defining the energy spectrum and the accuracy of the WKB is in direct proportion to control over the saddle points. If one had the complete set of classical solutions, then a strong coupling approximation is possible, since one is no longer doing perturbation theory in some small parameter, but rather a functional expansion in solution space. However, the complete spectrum of classical solutions to non-linear systems is notorious for the analytic effort required to find it.
5.2 Energy-Efficient Low-Noise CMOS Image Sensor with Capacitor Array-Assisted Charge-Injection SAR ADC for Motion-Triggered Low-Power IoT Applications

As IoT is increasingly integrated into our everyday life, the demand for different sensor modalities, especially imaging, is rising. IoT imagers are often compact and have small form-factor batteries and thus must be designed with both low power (improving battery life) and high image quality (maximizing utility). Previously reported sensors [1, 2], along with this work, adopt motion-detection (MD) triggering of full-array capture where MD is performed on a heavily subsampled frame to enable continuous low-power operation. MD limits energy-hungry full-array captures to cases where activity is detected. To further reduce power consumption, the full-frame capture energy itself needs to be addressed, which is typically dominated by the ADC.
Molecular karyotypes of Eimeria tenella resolved by PFGE: an evaluation of different agaroses.

Molecular karyotypes that revealed size polymorphisms between homologous forms of chromosomes 1, 2, 3 or 4 in three strains of the coccidial parasite Eimeria tenella were derived by pulsed field gel electrophoresis (PFGE) using brands of agaroses marketed either specifically for PFGE or for purposes such as protein electrophoresis or the separation of small molecules of DNA. Chromosomes up to ~4 Mbp were well resolved in agaroses marketed for non-PFGE purposes and these products clearly provide useful alternatives when supplies of dedicated PFGE agaroses are limited or withdrawn.
Abstract SY23-02: Actions of the EMT Program in fostering malignant progression

The cell-biological program commonly termed the epithelial-mesenchymal transition (EMT) confers a variety of distinct traits on epithelial cells that express it, including many that enable primary carcinoma cells to complete most of the steps of the invasion-metastasis cascade. Among other traits, it confers increased resistance to various forms of therapy and a stem-cell phenotype, which appears to be tightly linked to tumor-initiating ability. In addition, mammary carcinoma cells expressing an EMT program show a reduced susceptibility to elimination by anti-CTLA4 checkpoint blockade relative to their more mesenchymal counterparts. Carcinoma cells rarely if ever execute a complete EMT program but instead venture only partway toward the mesenchymal state, resulting in cells that co-express both epithelial and mesenchymal traits. Moreover, tumor-initiating cells appear to co-express both epithelial and mesenchymal traits, indicating that cells that have moved too far into the mesenchymal state actually lose stemness and thus tumor-initiating powers. Citation Format: Robert A. Weinberg. Actions of the EMT Program in fostering malignant progression [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr SY23-02.
A People's History of Leisure Studies: The Great Race and the National Parks and U.S. Forests

For some time, researchers have discussed the relationship of the National Park Service (NPS) and other parks, parks and recreation, and outdoor recreation entities’ cultural engagement through a lens of needed and improved management that emphasizes culturally diverse outreach programming, but that also is aimed at a greater awareness of social marginality and the preponderance of racial preferences. While Santucci, Floyd, Bocarro, and Henderson (2014) particularly explored the potential influence of the organizational culture of the NPS for maintaining a traditional culture resistant to diversity-related changes as an effort on truly diversifying its staffing, programming, and outreach, there has never been a call to examine the historical influences of the culture of the NPS, the United States Forest Service (USFS), the overall environmental movement, and even our very conception of outdoor recreation within the leisure studies and recreation service provision literature. What is presented here is a discourse-historical approach of authored texts as primary sources of conservationist, preservationist, and interpretation legends, Gifford Pinchot, Madison Grant, and Charles M. Goethe (among others). The article calls into question as to how their natural history, biological anthropology, and preservationist ideological lens influenced their philosophical articulation of conservation, preservation, and interpretation. In particular, Grant worked on matters of preservation synergistically in tandem with his eugenics beliefs, as chiefly articulated in the eugenicist tome, The Passing of the Great Race (1916a). This seminal eugenics text informed Western interests in racial nativism, and highlighted the intersection of conserving “the best” in nature and among humanity. While Grant and Goethe’s relationship with eugenics has had more exposure, there has not been a reckoning of their views, as well as the views of Pinchot within leisure research and recreation practice. It is evident in taking a discourse-historical approach in examining these primary sources that the purity of race, enforced reproductive encouragement of the fit and the reproductive restriction of the unfit along racialized gender lines, were the most important factors in determining the fate of populations and the environment (The National Conservation Commission, 1909). The aim here is to highlight Pinchot, Grant, and Goethe and to focus on the social injustices that they advocated as a basis to highlight the calls of social justice through this special issue and by way of the work of others who have championed the need for social justice perspectives within leisure studies and parks and recreation service delivery against their various ideals. Subscribe to JPRA