cssi/SciSciGPT-SciSciNet huggingface dataset:
Integration of the "How people learn" framework into educational module development and implementation in biotechnology

A team of domain experts, learning scientists, learning technologists, assessment experts and students are currently working on developing and refining educational tools for biotechnology as well as for other domains within the "How People Learn" framework in the NSF funded VaNTH ERC in Bioengineering Educational Technologies. Educational modules In biotechnology cover a collection of challenges designed around bioreactors, mass and momentum transfer issues, and microbial kinetics, which are among core biotechnology topics. The activities form the core of the STAR Legacy Cycle method that was adopted as the template for module development. These modules have been tested in classrooms both at Vanderbilt and Northwestern and detailed assessment data have also been collected. The focus of this contribution is on development and implementation of these educational modules at two universities (VU and NJU).
SRAM cell design for stability methodology

SRAM stability during word line disturb (access disturb) is becoming a key constraint for V/sub DD/ scaling (Burnett, 1994). In this paper we present a design methodology for SRAM stability during access disturb. In this methodology, the SRAM access disturb margin (ADM) is defined as the ratio of the magnitude of the critical current to maintain SRAM stability (I/sub CRIT/) to the sigma of I/sub CRIT/. Using ADM as a figure of merit, this methodology enables one to project the cell stability margin due to process variations, e.g. V/sub T/ variation, during design of a SRAM cell. Using statistical analysis, the required stability margin for an application requirement such as array size and available redundancy can be estimated. Direct cell probing and array test can be used to verify that the stability target is met.
Assessment of Public Knowledge and Willingness to Pay for Recovery of an Endangered Songbird, the Golden-Cheeked Warbler

ABSTRACTEcological economics assigns value to resources. Valuation can be difficult when the resource is a species, particularly one that does not directly impact humans. The endangered golden-cheeked warbler (Setophaga chrysoparia) is a songbird that breeds exclusively in central Texas. Using a door-to-door survey design, we investigated knowledge and willingness to pay for golden-cheeked warbler recovery actions in Austin, Texas, a city attempting to balance human population growth with conservation of several endangered species. Approximately half of respondents had knowledge of this species; of those 80% knew it was endangered. Seventy-four percent of respondents believed the species held value, and most regarded that value as existence-based. The mean willingness to pay was $21.47 per person annually over a 5-year period, including individuals not willing to pay. Our study indicated the public values the warbler, and is willing to provide monetary support for recovery and conservation efforts.
The aesthetic and ecstatic dimensions of soccer: towards a philosophy of soccer

Soccer remains to be the most played and watched form of sport at the international level, and soccer games bring together millions of people. The beauty and the playfulness of the game and its appeal to the many from different social strata are both the source of greatness of this sport and yet also related to its social problems. None of these problems, in my view, are inherent to soccer itself, but soccer, just like any other sport, is a microcosm of the world in which it lives and reflects its problems. In this essay, I would like to explore the aesthetic and the ecstatic dimensions of soccer and show how the spirit of soccer is antithetical to the social phenomena listed above. Under the aesthetic dimension, I will approach soccer insofar as it is the field of playfulness, game-making, imagination and beauty. Under the ecstatic dimension, I will attempt to understand how soccer creates a community, an ecstatic communion, around a sporting event.
Studies on the Feeding, Reproduction, and Development of Amblyseius hibisci (Acarina: Phytoseiidae) on Various Food Substances

Test mites of Amblyseius hibisci (Chant) were confined on excised avocado or citrus leaves in the laboratory at 72°–75°F. Adults fed and reproduced readily (oviposition approximately 1 egg per female per day) on the tetranychid mites Panonychus citri (McGregor), Oliyonychus punicae (Hirst), and Eotetranychus sexmaculatus (Riley), but reproduction was low (0.37 eggs per female per day) and mortality high on Tetranychus cinnabarinus (Boisduval). The predators were hindered by, and often trapped in, the copious webbing network produced by T. cinnabarinus. The citrus rust mite, Phyllocoptruta oleivora (Ashmead), also was fed upon but little reproduction occurred. Calvolia lordi (Nesbitt) (Saproglyphidae), 2 species of Tydeidae, and Cheletomimus berlesei (Oudemans) were not favorable prey species. Reproduction and development of A. hibisci occurred readily on pollen from various plant species, especially Persea americana, Ricinus communis, Capsicum frutescens, Zea mays, Mesembryanthemum, and Quercus. Developmental period was shorter and reproductive rate higher than on tetranychid mite prey. The preoviposition period for individuals developing on pollen was almost invariably 2 days, but was 2–6 days for individuals developing on mite prey. When both mite prey and pollen were available, both were fed upon with no distinct preference being evident. Mealybug honeydew without other food furnished adults sufficient nutrition for a low rate of reproduction and prolonged survival. Honeydew plus mite prey and honeydew plus pollen, respectively, stimulated a higher rate of reproduction than mite prey alone and pollen alone. Individuals developing on mite prey with honeydew had a shorter average preoviposition period than those developing on mite prey only. The possible significance of these responses is discussed in relation to population trends observed in the field.
CARB: A C-State Power Management Arbiter for Latency-Critical Workloads

Latency-critical workloads in datacenters have tight response time requirements to meet service-level agreements (SLAs). Sleep states (c-states) enable servers to reduce their power consumption during idle times; however entering and exiting c-states is not instantaneous, leading to increased transaction latency. In this paper we propose a c-state arbitration technique, CARB, that minimizes response time, while simultaneously realizing the power savings that could be achieved from enabling c-states. CARB adapts to incoming request rates and processing times and activates the smallest number of cores for processing the current load. CARB reshapes the distribution of c-states and minimizes the latency cost of sleep by avoiding going into deep sleeps too often. We quantify the improvements from CARB with memcached running on an 8-core Haswell-based server.
Characteristics and Improvement of Capacitance Wire Alignment Transducers and Coordinatographs

The capacitance instruments have been extensively used in worldwide projects.The principles,performance and characteristics of the capacitance instruments are introduced.With the technical progress,the improved methods for the capacitance instruments are discussed from the two aspects of raising the insulativity and the measuringstability.
Maximizing Corporate Productivity Gain Strategy Through Teambuilding and Group Creative Problem Solving

A trend or phenomenon appears to be taking place in our world of work. As ever increasing amounts of impersonal technology is introduced to the workplace, (e.g. robots and computers) a corresponding need arises for employees to increase their interaction and contacts with one another at work. In addition to this human need for increased employee interaction, a second need by management continues to demand greater amounts of attention. This management need is to rapidly obtain the best ideas to keep the organization competitive in today’s fast changing technological world.
Validity of the Cancer of the Prostate Risk Assessment Score Derived From Targeted Biopsy: Modeling Evidence From Ultrasound Lesion-Directed Biopsy

Abstract Objective Our aim was to evaluate the impact of direct, ultrasound lesion-targeted prostate biopsy, alone or in combination with systematic sampling, on prostate cancer risk prediction. Materials and Methods We reviewed biopsy findings for men with known or clinical suspicion of prostate cancer undergoing direct, ultrasound-targeted biopsy of radiographic lesions with concomitant systematic extended peripheral zone biopsy. We examined the resulting tumor volume estimates, Gleason grade, and Cancer of the Prostate Risk Assessment score generated from each strategy. Resulting multivariate clinical models of adverse surgical pathology—defined as high grade (Gleason pattern, ≥ 4+3) or non–organ-confined disease (≥ pT3a) were compared by the area under the Receiver Operating Characteristic curve. Results A total of 352 patients received ultrasound-targeted biopsy. At diagnosis, the mean age was 63 years, median prostate-specific antigen, 5.7 ng/mL (interquartile range, 4.3-8.2), and median 15 cores (interquartile range, 12-18). The addition of targeted cores to systematic biopsy resulted in reclassification of 52 patients (14.7%) based on Gleason score, 45 (12.8%) by percentage of cores involved > 33%, and 51 (14.5%) by single core positivity > 50%; Cancer of the Prostate Risk Assessment risk category increased in 44 (12.5%). In multivariable logistic regression models of 196 men treated with prostatectomy, the area under the Receiver Operating Characteristic curve for the prediction of adverse pathology generated from targeted (0.754), systematic (0.753), and combined approaches (0.763) were not significantly different ( P = .831). Conclusions The validity of clinical risk prediction assessed with a multi-variable instrument was maintained in the setting of lesion-targeted biopsy.
Anti-immigration Policies and Fear of Deportation: A Human Rights Issue

This paper examines how recent immigration policies and immigration enforcement strategies have impacted Latino immigrants in Arizona. Data were drawn from a sample of adult Latino immigrants (n = 213) living in Arizona. Analyses examined the relationship between fear of deportation and the impact of immigration policies on various aspects of daily life of Latino immigrants as a result of US immigration policies. Results indicate that participants who reported a greater fear of deportation were also significantly more likely to report: (1) trouble keeping a job; (2) trouble finding a job; (3) having been asked for immigration documents; (3) that friends have suffered; (4) that their family has suffered; (5) lower confidence that police will treat Latino immigrants fairly; (6) lower confidence that the courts will treat Latino immigrants fairly; and (7) lower confidence that they will have a better future. Implications for social work practice, advocacy, and research are discussed.
Patterns and drivers for wetland connections in the Prairie Pothole Region, United States.

Ecosystem function in rivers, lakes and coastal waters depends on the functioning of upstream aquatic ecosystems, necessitating an improved understanding of watershed-scale interactions including variable surface-water flows between wetlands and streams. As surface water in the Prairie Pothole Region expands in wet years, surface-water connections occur between many depressional wetlands and streams. Minimal research has explored the spatial patterns and drivers for the abundance of these connections, despite their potential to inform resource management and regulatory programs including the U.S. Clean Water Act. In this study, wetlands were identified that did not intersect the stream network, but were shown with Landsat images (1990–2011) to become merged with the stream network as surface water expanded. Wetlands were found to spill into or consolidate with other wetlands within both small (2–10 wetlands) and large (>100 wetlands) wetland clusters, eventually intersecting a stream channel, most often via a riparian wetland. These surface-water connections occurred over a wide range of wetland distances from streams (averaging 90–1400 m in different ecoregions). Differences in the spatial abundance of wetlands that show a variable surface-water connection to a stream were best explained by smaller wetland-to-wetland distances, greater wetland abundance, and maximum surface-water extent. This analysis demonstrated that wetland arrangement and surface water expansion are important mechanisms for depressional wetlands to connect to streams and provides a first step to understanding the frequency and abundance of these surface-water connections across the Prairie Pothole Region.
Marcantonio Raimondi’s Orpheus Enchanting the Animals: Intersection of Prints Between North and South

SummaryArt historians have often characterized the Italian Marcantonio Raimondi (c. 1480-before 1534) as a foremost reproductive engraver. This view was based mainly on the artist’s activity in Rome when he worked after Raphael’s designs. Until recently, his pre-Roman years were less frequently treated. It has been widely known that he borrowed motifs from Northern sources as Albrecht Durer (1471–1528) and Lucas van Leyden (c. 1494–1533). This essay suggests that Marcantonio drew inspiration, especially in his Bolognese years, from the works of two early engravers from the Upper Rhine, the Master E.S. (active c. 1450–1467), and the Master of the Playing Cards (active c. 1430–1450). He did not copy line-to-line motifs from these masters, however, but reinvented some of their work and imaginatively incorporated them into his own print, Orpheus Enchanting the Animals, c. 1505. This new engraving shows the artist’s creative strength and ability as an independent thinker. The fact that some other North Italian...
Severe Hallux Valgus With Coalition of the Hallux Sesamoids Treated With Modified Lapidus Procedure: A Case Report.

Coalition of the hallux sesamoids is an extremely rare condition. To our knowledge, only 1 case report has been published. We report a case of severe hallux valgus deformities with coalitions of the hallux sesamoids. The coalitions themselves were asymptomatic; however, this severe hallux valgus deformity needed to be surgically treated. The hallux sesamoids in both feet appeared to be fused and heart shaped on anteroposterior radiographs and dumbbell shaped on axial radiographs. It is known that postoperative incomplete reduction of the medial sesamoids can be a risk factor for the recurrence of hallux valgus. The computed tomography scan demonstrated a groove in the bottom of the center of the heart-shaped sesamoid. The flexor hallucis longus tendon was located in the groove. Therefore, a modified Lapidus procedure was performed considering the medial half of the heart-shaped sesamoid as the medial sesamoid. Although delayed union occurred, successful correction of the deformity was achieved. Levels of evidence Level IV.
Abstract 94: Nitric Oxide--Regulated RGS4 Loss of Function Coordinates Vascular Growth with Cardiomyocyte Growth in the Absence of External Hypertrophic Stimuli

The mechanisms that coordinate an increase in vasculature with cardiomyocyte growth in adult heart are not known. We report that induction of angiogenesis is sufficient to promote cardiomyocyte growth and myocardial hypertrophy through a novel nitric oxide (NO)-dependent mechanism. Our hypothesis is that an increase in endothelial-derived NO release promotes the proteosomal degradation of negative regulator of G protein signaling RGS4 in cardiomyocytes (CM) thus relieving repression of hypertrophic stimulation through G proteins. Methods include cell culture systems and transgenic mouse models. We generated three conditional cardiac inducible mouse models: (1) to stimulate angiogenesis by transgenic expression of placental growth factor (PlGF); (2) to stimulate angiogenesis by PlGF and compensate for RGS4 degradation by transgenic expression of RGS4 in CM; and (3) to stimulate angiogenesis by PlGF in eNOS -/- mice. Results. In cultured rat neonatal CM, the treatment with a slow release NO donor resulted in increased degradation of RGS4 through the N-end rule pathway of protein degradation. RGS4 loss of function led to increase in cell size through Gbetagamma/PI3Kgamma-dependent Akt/mTORc1 activation. In mice, PlGF expression induced an increase in capillary/myocyte ratio and arteriolar branches (determined by microCT angiograms). Myocardial hypertrophy was induced subsequent to angiogenic stimulation and concurrent with increased in NO production. Consistent with in vitro data hypertrophic stimulation was associated with reduced RGS4 protein levels and robust activation of Akt/mTORc1 signaling. This hypertrophy was prevented by concomitant transgenic expression of RGS4 in CM, despite the persistence of angiogenesis, arteriogenesis, and increased NO release. Furthermore, the NOS inhibitor L-NAME or mTORc1 inhibitor rapamycin significantly attenuated RGS4 degradation, Akt/mTORc1 signaling, and heart size in PlGF-induced mice. A similar effect was observed upon conditional heart-specific PlGF expression in eNOS -/- mice. In conclusion, these findings support a novel NO/RGS4/G protein/Akt mechanism that couples vessel growth with myocyte growth and heart size in the absence of traditional hypertrophic stimuli.
Identification of key design parameters for earthquake resistance of reinforced concrete shell structures

Abstract Concrete roof shells have shown to be inherently able to sustain earthquakes, but the reasons for this apparent seismic resistance have been subject to limited research. Concrete shells exhibit a high structural efficiency and thus can be constructed very thin. Because of their relative lightweight nature, the earthquake forces induced in a thin shell structure are relatively low. However, the shape of a shell structure is typically established so that it performs optimally under gravity loads, carrying the loads to the foundations mainly through membrane action over the shell surface. Unanticipated horizontal forces induced by earthquakes generate bending stresses in concrete shell structures, which could lead to structural damage. Through a parametric study of 8 cm thick, concrete roof shells with a square plan, the research presented in this paper demonstrates that small to mid-sized (span
Wire-Free and Adenosine-Free Fractional Flow Reserve Derived From the Angiogram: A Promising Future Awaiting Outcomes Data.

Invasive measurement of coronary arterial stenosis pressure gradients during maximal arteriolar vasodilation provides key physiological insights into ischemia-producing lesions that drive clinical outcomes before and after percutaneous coronary intervention.1–4 Although invasive coronary pressure gradients obtained during maximal hyperemic flow (ie, fractional flow reserve [FFR]) in patients with coronary artery disease do not provide a quantitative measure of absolute myocardial perfusion,5 FFR-guided coronary revascularization improves symptoms and reduces major adverse cardiovascular events (primarily target vessel revascularization),6,7 and may improve prognosis in patients with a large burden of ischemia.5 See Article by Westra et al The measurement of FFR requires placement of a coronary guidewire within the artery of interest followed by induction of maximal coronary artery hyperemic flow, usually by infusion of intravenous adenosine. The instrumentation of the coronary circulation and use of a systemic vasodilator required to perform FFR are associated with small but nontrivial increases in cost, risk, and time, with limited reimbursement for such procedures. These limitations are reflected in the remarkably low adoption of invasive FFR in the real world.8 To address these barriers, several noninvasive and invasive alternatives to invasive FFR have emerged.9–17 Among the panoply of FFR alternatives, only the instantaneous wave-free ratio (iFR), an adenosine-free approach, has been shown to perform …
An fMRI study of finger tapping in children and adults.

Functional brain imaging studies have characterized the neural bases of voluntary movement for finger tapping in adults, but equivalent information for children is lacking. When contrasted to adults, one would expect children to have relatively greater activation, reflecting compensation for an underdeveloped motor system combined with less experience in the execution of voluntary movement. To test this hypothesis, we acquired functional magnetic resonance imaging (fMRI) data on 17 healthy right-handed children (7.48 ± 0.66 years) and 15 adults (24.9 ± 2.9 years) while they performed an irregularly paced finger-tapping task in response to a visual cue (left- and right-hand examined separately). Whole-brain within-group analyses revealed that finger tapping in either age group and for either hand activated contralateral SM1, SMA, ipsilateral anterior cerebellum, and occipital cortices. We used an ANOVA factorial design to test for main effects of Age Group (children vs adults), Hand (left vs. right), and their interactions. For main effects of Age Group, children showed relatively greater activity in left SM1 (extending into bilateral SMA), and, surprisingly, adults exhibited relatively greater activity in right pre-SMA/SMA (extending into left pre-SMA/SMA), right lateral globus pallidus, left putamen, and right anterior cerebellum. The interaction of Age Group × Hand revealed that while both groups activated right SM1 during left finger tapping and exhibited signal decreases (i.e., below fixation baseline) during right finger tapping, both these responses were attenuated in children relative to adults. These data provide an important foundation by which to study children with motor disorders.
Derelict of Duty

If obscenity were to claim any parentage to obsolescence, it might be through an inexact filiation illicited through an apprehension of language that might be qualified as untoward. Certainly, to insinuate myself, as I have done, into a work of Lusophone disobedience, without language, and wearing myself into its verb, is precisely the sort of act that might encourage the distribution of various punishments. These capital pains borrow directly from French, the language by which I came to translate Hilda Hilst from Portuguese.
Procedures for Mixed Mode Fracture Testing of Bonded Beams in a Dual Actuator Load Frame

Most of the common methods for conducting fracture tests on adhesively bonded specimens refer to pure mode measures and to traditional load frames, where only one actuator is present. The critical strain energy release rates that characterize mode I, mode II and mixed-mode I/II fracture of bonded adherends can be measured also using a dual actuator load frame in which there are two degrees of freedom. The geometry that is tested is the double cantilever beam (DCB) type. DCB specimens are commonly used in traditional load frames for pure mode I tests but the independent actuators permit testing at different levels of mode-mixity. The focus of this paper is to develop and present evaluations of experimental and analytical aspects for mixed-mode fracture tests performed with the dual actuators liad frame. In fact, tests performed woth the dual actuator instead of other techniques give new possibilities and simplify the experimental effort, but also introduces different possible issues. New testing procedures have to be implemented; goals of these procedures are to enhance the capabilities of the dual actuator frmae maintaining some of the advantages of other techniques already in use woth traditional testing and analysis. Moreover, Nonlinear geometrical effects during the tests can play a role and are evaluated in this paper.
Stress Fractures of the Foot and Ankle

Among athletes, stress fractures are common injuries, many of which occur about the foot and ankle. Typically they develop when a specific bone is subjected to repetitive loads that create microfractures at a rate faster than the body’s ability to compensate and repair them. The stresses are affected by training volume and intensity, as well as biomechanical factors specific to the athlete. The athlete’s healing ability is dependent on the overall metabolic status and the local environment of the bone that is fractured. Treatment varies depending on the location of the fracture, as some bones have a predisposition to slow healing times and complications, and other heal quite readily without aggressive treatment. Regardless, when treating stress fractures it is always necessary to tailor the program to the specific athlete, as well as to identify both intrinsic and extrinsic factors that may have contributed to the injury and may predispose the athlete to recurrence. High risk locations of stress fractures of the foot and ankle include the anterior cortex of the tibial diaphysis, the medial malleolus, the navicular body, the proximal fifth metatarsal, and the tibial sesamoid of the hallux.
Distribution of Additive Functions (mod 1)

In this chapter, largely under the impulse of Weyl’s classic paper on uniform distribution, we make an excursion into the study of additive functions (mod 1).
Lacrimal Gland Hormone Regulation

Paracrine mediators orchestrate the lacrimal gland's organization into ductal and acinar epithelial elements and its immunophysiology, that is, its maintenance of an optimal niche for dimeric immunoglobulin A (IgA)-secreting plasmacytes, secretion of secretory IgA, and prevention of inflammatory autoimmune responses. Transforming growth factor-beta (TGF-β) conveys important differentiation signals, but it may also be antiproliferative and pro-apoptotic. Prolactin, epidermal growth factor (EGF), and fibroblast growth factor (FGF) are suggested to convey important survival signals that abrogate TGF-β's deleterious influences. However, prolactin also exerts mitogenic and proinflammatory influences; TGF-β likely abrogates these. Pronounced cytophysiological and immunoarchitectural changes that the lacrimal gland undergoes during pregnancy suggest that reproductive hormones influence expression of both.
Link between absence seizures and t-type calcium channels

An animal model of human absence epilepsy containing a G to C mutation of the Cav3.2 T-type Ca2+ channel gene (Cacna1h) ties together the gene mutation, increased T-type Ca2+ channel activity and the epileptic phenotype. Mice lacking a related gene (Cacna1a) also show enhanced T-type Ca2+ current and increased susceptibility to absence seizures. On the other hand, mutations that decrease T-type Ca2+ channel activity in thalamocortical relay neurons display no spike–wave discharges associated with absence seizures. These animal models are supported by genetic studies showing defects in T-type Ca2+ channel function in humans suffering from epilepsy. Thus, in both human and animal studies, T-type Ca2+ channel antagonists show promise in the treatment of absence seizures.
Society of Agents: A Framework for Multi-Agent Collaborative Problem Solving

The development of multiple agent systems faces many challenges, including agent coordination and collaboration on tasks. Minsky's The Society of Mind provides a conceptual view for addressing these multi-agent system problems. A new classification ontology is introduced for comparing multi-agent systems. Next, a new framework called the Society of Agents is developed from Minsky's conceptual foundation. A Society of Agents framework-based problem-solving and a Game Society is developed and applied to the domain of single player logic puzzles and two player games. The Game Society solved 100% of presented Sudoku and Kakuro problems and never lost a tic-tac-toe game. The advantage of the Society of Agents approach is the efficient re-utilization of agents across multiple independent game domain problems and a centralized problem-solving architecture with efficient cross-agent information sharing.
IPUMS-Terra: integrated big heterogeneous spatiotemporal data analysis system

Big Geo Data promises tremendous benefits to the GIS Science community in particular and the broader scientific community in general, but has been primarily of use to the relatively small body of GIScientists who possess the specialized knowledge and methods necessary for working with this class of data. Much of the greater scientific community is not equipped with the expert knowledge and techniques necessary to fully take advantage of the promise of big spatial data. IPUMS-Terra provides integrated spatiotemporal data to these scholars by simplifying access to thousands of raster and vector datasets, integrating them and providing them in formats that are useable to a broad array of research disciplines. IPUMS-Terra exemplifies a new class of National Spatial Data Infrastructure because it connects a large spatial data repository to advanced computational resources, allowing users to access the needle of information they need from the haystack of big spatial data. The project is trailblazing in its commitment to the open sharing of spatial data and spatial tool development, including describing its architecture, process development workflows, and openly sharing its products for the general use of the scientific community.
Tribological characteristics of greases with and without metallo-organic friction-modifiers

ABSTRACTAn important focus of grease development is to minimize friction and wear while improving load bearing capacity. ASTM D2266 test method is commonly used to evaluate performance of grease at...
Edge Assisted Efficient Data Annotation for Realtime Video Big Data

There is a lack of efficient video data labeling mechanism for real-time applications. Most of the labeling solutions are designed for big data offline video analytics, however emerging real-time applications with video analytics and the data-centric global trend require real-time video analytics with real-time labeling/annotation. In this paper, we present a solution that provides a per frame custom metadata that can be easily encoded and decoded and overlaid with the video frame for labeling the relevant objects/scenes. The presented solution is implemented and tested in a pilot and is leveraging edge computing capabilities to minimize the cost of using the cloud (in terms of latency and additional network resources).
Chapter 14 – Artificial Organs

Expanding beyond the realm to consider functionalized tissues as replacements, the larger question is how larger functional ensembles of tissues can be portrayed as living organ substitutes for damaged or diseased organs. Three ideas are forwarded to present the current state of artificial organs, including the replication of kidney purification by dialysis, the development of onboard functional deployment system to replicate functional pancreas expression regulating blood sugar in sera, and tissue-engineered constructs to replace the bladder. The rationale for intervention is presented in these three distinguishing paradigms of organ substitution. And of course, in the realm of artificial organs, they compete and comingle with organ transplants overall.
Living One’s Theories: Moral Consistency in the Life of Émile Durkheim

This article investigates the relation between a theorist’s theories and his daily life practices, using Emile Durkheim as an example. That theory and practice should be consistent seems not only s...
Radiographic patterns of progression in patients with EGFR-mutant NSCLC undergoing EGFR TKI therapy.

e19108 Background: There is paucity of data about the radiographic patterns of progression in patients with EGFR mutant NSCLC undergoing EGFR TKI therapy. The progression may be linked to evolution...
Nonlinear models for a compressor stall phenomenon using a single pressure measurement

One of the aerodynamic instabilities that severely affect the performance of a high-speed compressor is the rotating stall. In this paper, the experimental pressure measurements associated with the stall phenomenon in a compressor is analyzed. Time series analysis reveals that this process can be a nonlinear one. Furthermore, the dynamical behavior of the compressor in the stall region is shown to be chaotic. More interestingly, several deterministic polynomial models of this process, obtained from experimental pressure measurements, is reported which successfully captures the underlying global dynamics.
Statistical power of dynamic occupancy models to identify temporal change: Informing the North American Bat Monitoring Program

Dynamic occupancy models provide a flexible framework for estimating and mapping species occupancy patterns over space and time for large-scale monitoring programs (e.g., the North American Bat Monitoring Program (NABat), the Amphibian Research and Monitoring Initiative). Challenges for designing surveys using the dynamic occupancy modeling framework include defining appropriate derived trend parameters, and providing usable tools for researchers to conduct project-specific sample size investigations. We present a simulation-based power analysis framework for dynamic occupancy models that allows for the incorporation of the underlying environmental space (i.e., as covariates) within a specific study region to inform sample size estimation. We investigate two definitions of temporal trend: (1) a gradual, sustained (linear or nonlinear) change over a period of many years, and (2) an abrupt increase or decrease between two time periods. We draw upon pilot data collected following NABat protocols to inform assumed data generating values in a demonstration of our approach. Due to the complicated parameter structure of dynamic occupancy models, we emphasize the importance of visualizing simulated changes over time based on different parameter settings prior to conducting a power analysis. Our simulations revealed that the linearity of short-term trends (five years in our investigation) conferred higher power with lower sample size than longer trends where occupancy probabilities approached zero (ten years in our investigation). We provide an example of how to use our tools to conduct customized investigations using questions posed by NABat, and in doing so, we shed light on general guidelines that can be applied to programs monitoring species occupancy for other taxa. Importantly, we created an R package to execute our approach for informing program-, species-, and study-specific investigations aimed at identifying changes in species occupancy.
Effect of implementation of a new inpatient diabetes curriculum on resident education and clinical decision making

Objective: To identify the gaps in resident knowledge of inpatient diabetes management, education, and home insulin regimens. We postulate that identifying deficits and providing an intervention will lead to improvements in inpatient diabetic education, medical safety, and ensure successful transition to outpatient care. Background: The incidence of type 1 diabetes in the pediatric population is projected to increase by 23% by 2050, resulting in increased health care needs and cost. Due to limited financial and healthcare resources, the care and education …
Reducing Racial Bias Embedded in Land Use Codes

Even though the Supreme Court struck down race-based land use controls over a hundred years ago in Buchanan v. Warley, it has long been known that zoning continues to create or exacerbate racial and economic segregation. Today, communities across the U.S. are reexamining their zoning regulations to create more equal, equitable, inclusive, and resilient communities by removing requirements, limitations, or prohibitions that disproportionately and negatively impact individuals based on race or class. This article surveys twenty-three recommendations communities can implement to help address racial and class-based injustice. The recommendations are not all-encompassing. They focus specifically on common “neutral” land use provisions. These are provisions that do not mention race, but nonetheless may have widespread deleterious effects based on race or class. Not every recommendation is applicable to every community, and many communities have acted on some of these recommended areas. The purpose of listing the recommendations is to bring them together in a single list and to provide a starting point to view zoning as a positive force for inclusion and racial justice. The recommendations are categorized in five groups: increasing home ownership and security, accommodating diversity of employment opportunities, increasing food security and sovereignty, increasing pedestrian mobility and safety, and increasing inclusion in land use processes.
Neoliberalism and the (Im)possibility of the Affective Novel

This paper begins by mapping what it calls the ‘affect-neoliberal’ debate in contemporary literary studies. This debate, centred on the relationship between the personal-affective novel and neolibe...
Abolish The Employer Prerogative, Unleash Work Law

Employers are sovereigns in their workplace. Market power disparities, enforcement gaps, and the dwindling power of the beaten US labor movement seem to guarantee that. But it is law that anoints employers as kings. Work law doctrine calls it the “employer prerogative,” and it stands as the default governing rule in the workplace. This rule lays the basic legal structure of the workplace: all decisions fall within the employer’s discretion unless altered by contractual agreements or mandated differently by a statute or court doctrine. The entire array of legal interventions in the workplace, and their accompanying normative debates, flows from this legal rule. This Article calls to abolish the employer prerogative. It is too sticky, and subsequently, it skews all of work law theory and practice toward management interests. The Article begins by describing how the cumulative effects of a judicial presumption of prerogative, labor market power disparities, the employment at-will doctrine, and enforcement gaps make modifying this default a Sisyphean task. The argument follows by describing two mechanisms that tie the employer prerogative to the uphill political struggle of redistributing power in the workplace. To preserve their control, employers can use their prerogative to evade workplace interventions or punish workers and their communities for pursuing redistributive workplace policies. At the expense of any goal work law advocates might pursue, the employer prerogative is self-entrenching. Perhaps the most troubling aspect of this default rule is that challenging it is a taboo of a sort. Hence, the Article concludes by offering a novel framework for considering possible alternatives to it. The Article describes alternative default governance rules and presents a set of new and renewed legal institutions designed to reallocate these default authorities among multiple stakeholders. These novel interventions offer the structural analysis and remedies vitally needed to correct the workplace’s skewed status quo of power and to actualize work law’s potential – unleashing it from its employer prerogative constraints.
Looking Back, Looking Forward

Responding to the honor of the festschrift, I name and honour those who guided me, especially my mentor, Elliot Mishler. I describe a path from initial fascination with the idea of a “story” to my subsequent work that expanded the study of narrative in the human sciences. Efforts to understand how individuals interpreted—made sense of—events and situations that had interrupted their lives led me to discoveries about narrative form, apparent only after close textual interactional analysis. Recently, the appeal of narrative has mushroomed; I urge scholars not to lose sight of features that distinguish it from other forms of discourse.
Assessing the Impact of a High Impact Practice: Implementing a Criminal Justice Shared Learning Experience Using the True Crime Podcast Serial

Common high-impact practices include a diverse menu of curricula. One practice growing in popularity is the shared learning experience. Shared learning is an extension of the learning community con...
The Making of Global Black Anti-Citizen/Citizenship: Situating BlackCrit in Global Citizenship Research and Theory.

Our current moment is abundant in examples of global antiblackness whereby racial violence visibly signals the quotidian elimination of Blackness, or the making of Black people into an object or ab...
The Role of Biomarkers in Surgery for Ulcerative Colitis: A Review

Ulcerative colitis (UC) is an inflammatory condition that generally affects the rectum and extends proximally into the colon in a continuous, distal-to-proximal pattern. Surgical resection (total proctocolectomy) is the only cure for UC and is often necessary in managing complicated or refractory disease. However, recent advances in biologically targeted therapies have resulted in improved disease control, and surgery is required in only a fraction of cases. This ever-increasing array of options for medical management has added complexity to surgical decision-making. In some circumstances, the added time required to ensure failure of medical therapy can delay colectomy in patients who will ultimately need it. Indeed, many patients with severe disease undergo trials of multiple medical therapies prior to considering surgery. In severe cases of UC, continued medical management has been associated with a delay to surgical intervention and higher rates of morbidity and mortality. Biomarkers represent a burgeoning field of research, particularly in inflammatory bowel disease and cancer. This review seeks to highlight the different possible settings for surgery in UC and the role various biomarkers might play in each.
High Temperature Acclimation of Leaf Gas Exchange, Photochemistry, and Metabolomic Profiles in Populus trichocarpa

Author(s): Dewhirst, RA; Handakumbura, P; Clendinen, CS; Arm, E; Tate, K; Wang, W; Washton, NM; Young, RP; Mortimer, JC; McDowell, NG; Jardine, KJ | Abstract: High temperatures alter the thermal sensitivities of numerous physiological and biochemical processes that impact tree growth and productivity. Foliar and root applications of methanol have been implicated in plant acclimation to high temperature via the C1 pathway. Here, we characterized temperature acclimation at 35 °C of leaf gas exchange, chlorophyll fluorescence, and extractable metabolites of potted Populus trichocarpa saplings and examined potential influences of mM concentrations of methanol added during soil watering over a two-month period. Relative to plants grown under the low growth temperature (LGT), high growth temperature (HGT) plants showed a suppression of leaf water use and carbon cycling including transpiration (E), net photosynthesis (Pn), an estimate of photorespiration (Rp), and dark respiration (Rd), attributed to reductions in stomatal conductance and direct negative effects on gas exchange and photosynthetic machinery. In contrast, HGT plants showed an upregulation of nonphotochemical quenching (NPQt), the optimum temperature for ETR, and leaf isoprene emissions at 40 °C. A large number of metabolites (867) were induced under HGT, many implicated in flavonoid biosynthesis highlighting a potentially protective role for these compounds. Methanol application did not significantly alter leaf gas exchange but slightly reduced the suppression of Rd and Rp by the high growth temperature while slightly impairing ETR, Fv′/Fm′, and qp. However, we were unable to determine if soil methanol was sufficiently taken up by the plant to have a direct effect on foliar processes. A small number of extracted leaf tissue metabolites (55 out of 10 015) showed significantly altered abundances under LGT and methanol treatments relative to water controls, and this increased in compound number (222) at the HGT. The results demonstrate the large physiological and biochemical impacts of high growth temperature on poplar seedlings and highlight the enhancement of the optimum temperature of ETR as a rapid thermal acclimation mechanism. Although no large effect on leaf physiology was observed, the results are consistent with methanol both impairing photochemistry of the light reactions via formaldehyde toxicity and stimulating photosynthesis and dark respiration through formate oxidation to CO2.
The Sea and Poison: Shusaku Endo’s Prelude to Silence

This chapter focuses on Shusaku Endo’s The Sea and Poison (1958) as a prelude to better understanding his novel Silence (1966). This particular novel shows how Endo was able to introduce Christian characters into the plot (without having to label them) and how these may not be what one would expect from a Japanese Catholic writer. The Sea and Poison was inspired by the experiments in human vivisection on American prisoners of war by Japanese authorities during World War II. In contrast to most critics of Endo’s work, who view it through a Christian lens, this chapter employs a non-religious perspective on this complex topic. In addition to vindicating Japanese cultural and ethical values, novels like Silence and The Samurai (Endo’s last published work, 1980) reveal much more about colonialism and, in a way, “coloniality” than about the persecution of Catholics in sixteenth-century Japan.
The Network Effects of Agency Conflicts

It is customary to focus on the network of interdependencies between firms to understand how and whether a shock to one firm will propagate to others. This paper argues that agency conflicts at the firm-level and not just the network structure, play a crucial role in amplifying or muting the propagation of exogenous shocks. If firms can take investment decisions in response to an exogenous shock, whether their choices amplify or mute the propagation of the shock will depend on the nature of the agency conflict. When agents in our model are subject to default costs or limited liability, they make investment choices that serve to mitigate the spread of an initial shock. In the face of interest conflicts or moral hazard, however, shocks are amplified by firm-level investment choices. The presence of these agency conflicts counters the role of network structure in the propagation of shocks. For example, prior work argues that denser or more integrated networks facilitate the propagation of shocks. We show that in the presence of interest conflicts, this effect can be reversed. Under some conditions, the aggregate effect of an idiosyncratic shock via propagation does not diminish. This suggests a potentially important role that corporate governance plays in macro fluctuations.
Investigation of alkaline–crude oil reaction

Abstract One of the mechanisms of alkaline flooding relies on alkaline reaction with organic acids (saponifiable components) in the crude oil to produce an in situ surfactant called soap that lowers interfacial tensions. However, this mechanism is not quantified in the literature. For example, what is the fraction of acid components which react with alkaline solution to generate soap? How much soap can be generated? In this paper, this mechanism and related issues are discussed, analyzed or quantified. In particular, the numerical simulation approach is used. The results show that only a fraction of acid components can be converted into soap; the amount of generated soap could be low. A minimum pH (e.g. 9) is needed for the acids to be converted to soap. The literature information on the effect of amount of acid components (total acid number) on oil recovery is also discussed.