cssi/SciSciGPT-SciSciNet huggingface dataset:
THE RELATION OF DIEL PATTERNS OF CELL DIVISION TO DIEL PATTERNS OF MOTILITY IN THE SYMBIOTIC DINOFLAGELLATE SYMBIODINIUM MICROADRIA TICUM FREUDENTHAL IN CULTURE

SUMMARY Frequency of binary fission in cultures of three strains of the symbiotic dinoflagellate Symbiodinium microadriaticum, isolated from the anemones Aiptasia tagetes, Heteractis lucida and the jellyfish Cassiopeia xamachana, was related to their diel patterns of motility. Under a 14:10 h light:dark cycle, karyokinesis, cytokinesis and motility occur diurnally. The highest frequency of cytokinesis preceded highest motility by 4 to 7 h. Karyokinesis preceded cytokinesis by 1 to 5 h. Generally, the ratio of number of dividing cells to the number of motile cells recorded in exponentially growing cultures was 1:2, suggesting that two motile cells arise from one newly divided zooxanthella. No motile cells were seen in stationary cultures. Algae grown at high irradiance (180/μE m−2 s−1) had higher growth rates and higher levels of motility than those grown at lower irradiance (15 μE m−2 s−1). Under constant light or dark conditions, patterns of cytokinesis and motility were circadian. In darkness the rhythm tapered out after about 1 week. The patterns were evident for up to 7 days in constant dim light, but tended to dampen out with time. These results suggest that current views of the life cycle of S. microadriaticum need to be modified, and we propose some alternatives which are consistent with our observations.
A METHODOLOGY FOR MODELING MULTI-AGENT SYSTEMS USING NESTED PETRI NETS

In the past two decades, multi-agent systems have emerged as a new paradigm for conceptualizing large and complex distributed software systems. Even though there are many conceptual frameworks for using multi-agent systems, there is no well established and widely accepted method for the representation of multi-agent systems. We adapt a well-known formal model, predicate transition nets, to include the notions of dynamic structure, agent communication and coordination to address the representation problems. This paper presents a comprehensive methodology for modeling multi-agents based on the extensions. We demonstrate our modeling approach with an example. Several case studies on different application domains from our previous works are also discussed.
The Effects of Different Reinforcement Conditions on the Test Performance of Multihandicapped Deaf Children.

The present study explored the effects of different reinforcement conditions on the number of correct responses on the Rvaen Progressive Matrices. Four groups of 11- to 18-year-old multihandicapped deaf children matched on the basis of mean age and pretest scores were used. The groups were randomly assigned to any of four posttest conditions: end-of-session reinforcement, noncontingent reinforcement, delayed reinforcement, and immediate reinforcement. The mean posttest score of subjects tested under the immediate-reinforcement condition was significantly higher than that of any other group. No significant differences were observed between the mean posttest scores of the three other groups. The practical implications of using reinforcement procedures for testing purposes are discussed.
Hierarchical Segmentation of Surfaces Embedded in R3 for Auto-Body Painting

Complete automation of trajectory planning tools for material deposition/removal applications has become increasingly necessary to reduce the “concept-to-consumer” timeline in product development. Segmentation of a complex automotive surfaces into topologically simple surfaces remains a barrier in the automation of trajectory generation. In this paper, we develop a novel hierarchical procedure to segment a complex automotive surface into geometrically as well as topologically simple components.
Neuroplasticity after spinal cord injury and training: an emerging paradigm shift in rehabilitation and walking recovery

Physical rehabilitation after spinal cord injury has been based on the premise that the nervous system is hard-wired and irreparable. Upon this assumption, clinicians have compensated for irremediable sensorimotor deficits using braces, assistive devices, and wheelchairs to achieve upright and seated mobility. Evidence from basic science, however, demonstrates that the central nervous system after injury is malleable and can learn, and this evidence has challenged our current assumptions. The evidence is especially compelling concerning locomotion. The purpose of this perspective article is to summarize the evidence supporting an impending paradigm shift from compensation for deficits to rehabilitation as an agent for walking recovery. A physiologically based approach for the rehabilitation of walking has developed, translating evidence for activity-dependent neuroplasticity after spinal cord injury and the neurobiological control of walking. Advanced by partnerships among neuroscientists, clinicians, and researchers, critical rehabilitation concepts are emerging for activity-based therapy to improve walking recovery, with promising clinical findings.
Canine coronavirus-associated puppy mortality without evidence of concurrent canine parvovirus infection

This report presents 2 cases in which puppy fatalities were associated with canine coronavirus (CCV), but no evidence of concurrent canine parvovirus (CPV-2) disease was observed. Case 1 involved a 7-week-old, male short-haired Chihuahua, which had become lethargic 24 hours after purchase from a pet store. Within 72 hours, the puppy began to vomit, had diarrhea, and was admitted to the veterinary clinic, where it was placed on IV fluids. The parvovirus Cite test was negative. The puppy died within 12 hours of admission and was submitted for diagnostic workup. Gross pathology revealed an enteritis suggestive of CPV-2. Histopathology on intestines showed scattered dilated crypts with necrotic cellular debris and neutrophils. There was moderate depletion and necrosis of lymphoid follicles. Electron microscopy (EM) on intestinal contents was positive for coronavirus and negative for parvovirus. Immunohistochemistry (IHC) on gut sections was positive for CCV and negative for CPV-2. Case 2 was an 8-week-old, male Shih Tzu, which was admitted to the veterinary clinic exhibiting symptoms of severe gastroenteritis with abdominal pain. The referring veterinarian euthanized the puppy, and the entire body was submitted for diagnostic evaluation. Necropsy revealed a severe ileo-cecal intussusception and segmental necrotic enteritis of the small intestine. Electron microscopy of the intestinal contents was positive for coronavirus and negative for parvovirus. Immunohistochemistry on sections of affected gut were positive for CCV and negative for CPV-2. These cases emphasize the importance of pursuing a diagnosis of CCV in young puppies when CPV-2 disease has been ruled out by IHC.
Chronic Monitoring of Intraventricular Pressure in Children Using Telemetry: Engineering and Physiologic Aspects

Acute monitoring of intracranial pressure via external ventricular drainage systems carries low risk when the implantation is for short periods of time (usually less than ten days) (Smith and Alksne 1976). As the length of time the device is used increases, the risk of infection increases (Rekate 1976). During the period of monitoring the patient is continuously restricted in movement by the drainage system. There are certain pathologic States in which prolonged monitoring of intracranial pressure would be clinically useful. These include hydrocephalus, some metabolic encephalopathies, and patients with brain tumors undergoing chemotherapy. For these purposes the Electronics Design Center of the School of Engineering is developing a device for the continuous monitoring of intraventricular pressure by telemetry. This report will deal with the development of, and clinical experience with, this device.
Discriminant Analysis of Transmission of Elevated Blood Pressure in First Generation Offspring of African Green Monkeys

A linear discriminant analysis was applied to blood pressure data of 162 first generation colony-born offspring of normotensive (C), hypertensive (H), or borderline hypertensive (B) African green monkeys who were being selectively bred in an attempt to establish a strain of spontaneously hypertensive monkeys. The offspring were classified according to their parents' blood pressures as CC, HH, or Mixed (e.g. HC). Blood pressures were measured by indirect methods from unanesthetized offspring aged 0.5–6 years of age. The discriminant score was used to classify each of the 533 blood pressure measurements of the CC, Mixed, and HH offspring into one of three predicted groups: normotensive, borderline hypertensive, or hypertensive. The group means of the three predicted groups compared without regard to offspring type were significantly different (p<.001). In addition, the percentage of blood pressure measurements predicted to be normal or elevated differed among the three offspring groups (p<.001). 82% of the ...
Full-length RAG1 promotes contact with coding and intersignal sequences in RAG protein complexes bound to recombination signals paired in cis

The RAG proteins initiate V(D)J recombination by mediating synapsis and cleavage of two different antigen receptor gene segments through interactions with their flanking recombination signal sequences (RSS). The protein-DNA complexes that support this process have mainly been studied using RAG-RSS complexes assembled using oligonucleotide substrates containing a single RSS that are paired in trans to promote synapsis. How closely these complexes model those formed on longer, more physiologically relevant substrates containing RSSs on the same DNA molecule (in cis) remains unclear. To address this issue, we characterized discrete core and full-length RAG protein complexes bound to RSSs paired in cis. We find these complexes support cleavage activity regulated by V(D)J recombination's '12/23 rule' and exhibit plasticity in RSS usage dependent on partner RSS composition. DNA footprinting studies suggest that the RAG proteins in these complexes mediate more extensive contact with sequences flanking the RSS than previously observed, some of which are enhanced by full-length RAG1, and associated with synapsis and efficient RSS cleavage. Finally, we demonstrate that the RAG1 C-terminus facilitates hairpin formation on long DNA substrates, and full-length RAG1 promotes hairpin retention in the post-cleavage RAG complex. These results provide new insights into the mechanism of physiological V(D)J recombination.
Image synthesis and lens response using spot diagrams.

A simple shadowgraph is used to measure the square wave response of a lens system from its computed spot diagrams. Some fundamental aberrations are studied. Images of a silhouette test object are synthesized and compared to those produced by the lens system itself.
The LMA Supreme™ in 700 parturients undergoing Cesarean delivery: an observational study.

Background The LMA Supreme™ (SLMA) is a single-use supraglottic device that provides a good seal for positive pressure ventilation. It has a double aperture design that facilitates the introduction of an orogastric tube to aspirate gastric contents. This observational study evaluated the role of the SLMA in parturients undergoing Cesarean delivery under general anesthesia.
Is Top 10 Better than Top 9? The Role of Expectations in Consumer Response to Imprecise Rank Claims

AbstractMany marketing communications are carefully designed to cast a brand in its most favorable light. For example, marketers may prefer to highlight a brand’s membership in the top 10 tier of a third-party list instead of disclosing the brand’s exact rank. The authors propose that when marketers use these types of imprecise advertising claims, subtle differences in the selection of a tier boundary (e.g., top 9 vs. top 10) can influence consumers’ evaluations and willingness to pay. Specifically, the authors find a comfort tier effect in which a weaker claim that references a less exclusive but commonly used tier boundary can actually lead to higher brand evaluations than a stronger claim that references a more exclusive but less common tier boundary. This effect is attributed to a two-stage process by which consumers evaluate imprecise rank claims. The results demonstrate that consumers have specific expectations for how messages are constructed in marketing communications and may make negative infere...
A Systematic Approach to High Density Settings: Psychological, Social, and Physical Environmental Factors

The difficulties high density are viewed in light of behavioral constraints encountered and the experience of cognitive overload. These concepts are explained and several field experiments are reported supporting the importance of each separately and in interaction in determining responses to density. Perceptions of crowding stress spontaneously reported in an interview study of urban stress are then described; different place-related patterns of crowding stress and coping emerge from this analysis that confirm and extend the previous concepts. Finally several studies of high density residential environments are presented that lead to a more strongly ecological theoretical perspective.
MOLECULAR ALTERATIONS IN GLIOBLASTOMA: POTENTIAL TARGETS FOR IMMUNOTHERAPY

Glioblastoma is the most common and deadly brain tumor, possibly arising from genetic and epigenetic alterations in normal astroglial cells. Multiple cytogenetic, chromosomal, and genetic alterations have been identified in glioblastoma, with distinct expression of antigens (Ags) and biomarkers that may alter therapeutic potential of this aggressive cancer. Current therapy consists of surgical resection, followed by radiation therapy and chemotherapy. In spite of these treatments, the prognosis for glioblastoma patients is poor. Although recent studies have focused on the development of novel immunotherapeutics against glioblastoma, little is known about glioblastoma-specific immune responses. A better understanding of the molecular interactions among glioblastoma tumors, host immune cells, and the tumor microenvironment may give rise to novel integrated approaches for the simultaneous control of tumor escape pathways and the activation of antitumor immune responses. This review provides a detailed overview concerning genetic alterations in glioblastoma, their effects on Ag and biomarker expression, and the future design of chemoimmunotherapeutics against glioblastoma.
Diflubenzuron: Evaluation for Control of the Pink Bollworm, Cabbage Looper, and Cotton Leafperforator in a Field Cage Test

Diflubenzuron ( N -[[(4-chlorophenyl) amino]carbonyl]-2,6-difluorobenzamide), an insect growth inhibitor, was applied at 0.22 and 2.2 kg AI/ha to ‘Deltapine 16’ cotton in field cages. There was no control of the pink bollworm, Pectinophora gossypiella (Saunders), but excellent control of the cotton leafperforator, Bucculatrix thurberiella Busck, at both rates of application, and control of the cabbage looper, Trichoplusia ni (Hubner), at the highest rate.
3D Projected Imagery Freespace Control Unit (PIFCU): Design, Implementation, and Analysis

A desirable mechanism to control a computer would be to use a multifaceted, three-dimensional interactive display system that provides varying levels of control of an API via a visually bounded freespace containing projected imagery for interactions. This work presents such a system and its proof-of-concept, which includes two components: the 3D Projected Imagery Freespace Control Unit (PIFCU)-the built hardware used to create 3D imagery and function as the system’s control unit, and the Gesture-Controlled 3D Interface Freespace (GCIF)-the term used for this “sensorized” volume of space in which the 3D images and gestures will reside. This system is intended to ultimately remove the need for keyboards and similar interface hardware. The hardware of this device consists of an array of linearly adjoining slices of concave mirrored surfaces with openings at the top and bottom. This combination advances related work such that the imagery can be perceived as threedimensional images in free-space, and the computer is controlled using hand gestures recognized by sensors. The benefits to other professions include providing new methods of construction, navigation, gaming, as well as presenting a solution for certain physical limitations that traditional computing experiences currently exert on users (i.e. rigid hand angles for typing).
PIV on Simple Mechanical Flapping Wings for Hover-like Kinematics

A Particle Image Velocimetry (PIV) study on aspect ratio effects was performed to highlight the role of three-dimensional aerodynamic contributions relative to inertial contributions to lift and power for a hover-like passive pitch rotation flapping kinematic motion. Interest in the research and development of flapping wing micro air vehicles (MAVs) continues to grow. Despite the large body of work performed recently, an abundance of unanswered questions still exist. The approach taken in this study is to begin by reducing the complexity of the problem through parametric variation of a single geometric parameter, aspect ratio. The present PIV research has a parallel ongoing force acquisition experiment led by the US Air Force Research Labs (AFRL/RBAL). When the AFRL study has been completed, the lift and inertial force results will be used in conjunction with the PIV results to provide more insight into the physics behind the resulting forces. One important finding for the kinematics studied is that an intermediate aspect ratio (rectangular flat plate) wing will result in the greatest lift efficiency from the standpoint of both aerodynamics and power.
Competencies required! For education, recruitment, and retention

For a practice-based profession, librarianship has been slow to adopt competencies and standards for our practitioners in a majority of settings. Notable exceptions such as medical librarianship can provide some models, but science and technology libraries must go further if we expect the people in our operations to meet the needs of our users in this digital century. Recruitment and retention both should be based upon measurable performance standards and goals. This article discusses some sources upon which we can draw and from which we can adapt competencies and standards, as well as presenting some examples.
Evaluation of 1.5-T Cell Flash Memory Total Ionizing Dose Response

Flash memory is an essential part of systems used in harsh environments, experienced by both terrestrial and aerospace TID applications. This paper presents studies of COTS flash memory TID hardness. While there is substantial literature on flash memory TID response, this work focuses for the first time on 1.5 transistor per cell flash memory. The experimental results show hardness varying from about 100 krad(Si) to over 250 krad(Si) depending on the usage model. We explore the circuit and device aspects of the results, based on the extensive reliability literature for this flash memory type. Failure modes indicate both device damage and circuit marginalities. Sector erase failure limits, but read only operation allows TID exceeding 200 krad(Si). The failures are analyzed by type.
Predicting Phenology of Green Peach Aphid (Homoptera: Aphididae) using Degree-Days

A degree-day model for predicting the phenological events of green peach aphid, Myzus persicae (Sulzer), was developed on both primary (peach and nectarine) and secondary (potato) host plants. A degree-day method, mean-minus-base, was applied to predict 5 significant phenological events of holocyclic M. persicae . Occurrences of egg hatch, 1st alate, and alate emigration from primary host plants were observed at 24, 332, and 509 base 4°C degree-days (DD). On potato plants, immigration of M. persicae commenced at 864 DD and peak migration occurred at 1,278 DD. The timing of these phenological events in both primary and secondary hosts was not predictable in the chronological time scale. However, this study indicated that M. persicae phenology can be predicted precisely using a degree-day method.
TCTAP C-246 Device Closure of Remnant Ventricular Septal Defect in Post MI

### Patient initials or identifier number JP ### Relevant clinical history and physical exam Patient is a 62 year old man who presented to an outside hospital with complaints of substernal chest pain. The onset of the pain was about 12 hours prior to presentation. He was diagnosed with an acute
Using Internet Search Data to Produce State-level Measures The Case of Tea Party Mobilization

This study proposes using Internet search data from search engines like Google to produce state-level metrics that are useful in social science research. Generally, state-level research relies on demographic statistics, official statistics produced by government agencies, or aggregated survey data. However, each of these data sources has serious limitations in terms of both the availability of the data and its ability to capture important concepts. This study demonstrates how state-level Google search measures can be produced and then demonstrates the effectiveness of such measures in an empirical case: predicting state-level Tea Party movement mobilization. Drawing on existing studies of the Tea Party movement and theories of right-wing and conservative mobilization, state-level Google search measures for anti-immigrant sentiment and economic distress are developed and compared to traditional metrics that are typically used to measure these concepts, such as the unemployment rate and the international im...
Looking for homeland with homesickness——The modern value of the creative methods of realistic Art

In view of the existentialist theory of the day,the essence of the realism must be rescanned.The historical materialism is used to discuss the human's historical activity.The value of the soul ofthe realism can be discovered today when modern art is prevailing.The conclusion is that the method of the reali stlc art creation has huge vitality in not only nowadays.but also any eras.
Efficacy of Keshuxing No.1 against rodents

Objective To observe the efficacy of Keshuxing No.1 against SD rats and mice in both laboratory and field,and provide evidential support for practical selection of anticoagulant rodenticide.Methods Selective and nonselective feeding tests of Keshuxing No.1 against rats and mice were conducted in laboratory.Results The feeding indices of Keshuxing No.1 for SD rats and mice were 0.38 and 0.30 respectively in selective feeding tests.In nonselective feeding tests,the death rates of SD rats and mice were 100% and 90% respectively after 3 consecutive feeding.The killing rates of Keshuxing No.1 against mice and rat in the field tests were 92.86% and 91.67% respectively.Conclusion The palatability of Keshuxing No.1 for rat and mouse is good.It has very good killing effect on mouse and rat in both laboratory and field.Keshuxing No.1 can be an effective choice for chemical prevention and control of house mouse.
Survey of Awareness of Nowledge/ehaviors About AIDS Among Men Having Sex With Men and Their HIV Infection Status

Objective To understand the awareness of knowledge and behaviors about AIDS among men having sex with men (MSM) and their infection status in Yingtan,provided scientific basis for the implementation effective intervention.Methods The investigation plan was developed and anonymous questionnaire survey was conducted among MSM and blood samples were taken from them at the places where MSM gathered.Results A total of 135 MSM received the survey,65.93%-97.04% of them correctly answered questions about AIDS transmission route and prevention measures.The use rate of condom in the latest sex was 49.63%.Among 14 blood samples,1 was HIV positive.About 85.93% of MSM refused blood sampling.Conclusion The MSM still experienced high risk sex behaviors although most of them being aware of AIDS,a few of them received voluntary HIV test.
A screening tool for assessing alcohol use risk among medically vulnerable youth

BACKGROUND: In an effort to reduce barriers to screening for alcohol use in pediatric primary care, the National Institute on Alcoholism and Alcohol Abuse (NIAAA) developed a two-question Youth Alcohol Screening Tool derived from population-based survey data. It is unknown whether this screening tool, designed for use with general populations, accurately identifies risk among youth with chronic medical conditions (YCMC). This growing population, which comprises nearly one in four youth in the US, faces a unique constellation of drinking-related risks. METHOD: To validate the NIAAA Youth Alcohol Screening Tool in a population of YCMC, we performed a cross-sectional validation study with a sample of 388 youth ages 9-18 years presenting for routine subspecialty care at a large children's hospital for type 1 diabetes, persistent asthma, cystic fibrosis, inflammatory bowel disease, or juvenile idiopathic arthritis. Participants self-administered the NIAAA Youth Alcohol Screening Tool and the Diagnostic Interview Schedule for Children as a criterion standard measure of alcohol use disorders (AUD). Receiver operating curve analysis was used to determine cut points for identifying youth at moderate and highest risk for an AUD. RESULTS: Nearly one third of participants (n = 118; 30.4%) reported alcohol use in the past year; 86.4% (106) of past year drinkers did not endorse any AUD criteria, 6.8% (n = 8) of drinkers endorsed a single criterion, and 6.8% of drinkers met criteria for an AUD. Using the NIAAA tool, optimal cut points found to identify youth at moderate and highest risk for an AUD were ≥ 6 and ≥12 drinking days in the past year, respectively. CONCLUSIONS: The NIAAA Youth Alcohol Screening Tool is highly efficient for detecting alcohol use and discriminating disordered use among YCMC. This brief screen appears feasible for use in specialty care to ascertain alcohol-related risk that may impact adversely on health status and disease management. Language: en
Administrative pressure to practice unethically and burnout within the profession of school psychology.

This investigation involved the surveying of school psychology practitioners (N = 291) to determine the possible existence of a relationship between administrative pressure to practice unethically and impaired occupational health, as manifested in elevated levels of burnout, job dissatisfaction, and intent to exit the workforce. Almost one-third of participants claimed to have been pressured to behave unethically, with directives most commonly consisting of instructions to withhold recommendations for support services and to agree with inappropriate special education placement decisions. Practitioners who experienced administrative pressure reported higher levels of burnout, less satisfaction with their current position and the profession, and a greater desire to leave their job and the field of school psychology. The findings are presented within the context of current and projected shortages of practicing school psychologists. Implications for preventing burnout and promoting school psychologists’ occupational well-being are discussed.
Human alveolar macrophage arachidonic acid metabolism

Metabolites of arachidonic acid are potent modulators of many biological events, and their release from macrophages appears to play an important role in immune and inflammatory processes. In addition, metabolites of the cyclooxygenase or lipoxygenase pathway exhibit distinct biological effects. We used a method to determine if human alveolar macrophages (HAM) could be selectively activated to release products of cyclooxygenase or lipoxygenase pathway of arachidonic acid. HAM obtained by bronchoalveolar lavage from individuals were [3H]arachidonic acid labeled and then stimulated with lipopolysaccharide (LPS) or Ca ionophore A23187. Essentially no arachidonate metabolites were released by unstimulated cells. LPS caused dose- and time-dependent release of arachidonate and only cyclooxygenase products; no lipoxygenase products were detected, even in presence of cyclooxygenase inhibition. Metabolites released in response to LPS included thromboxane B2, prostaglandins D2, F2a, E2, and hydroxyheptadecatrienoic acid. A23187 caused a rapid release of arachidonate and 5-lipoxygenase products, leukotriene B4 and 5-hydroxyeicosatetraenoic acid; no cyclooxygenase inhibition. This demonstrates that HAM are specifically activated to release metabolites derived from cyclooxygenase or lipoxygenase pathway of arachidonic acid. Additionally, shunting down an alternate pathway is not induced by use of inhibitors of either pathway. This suggests alveolar macrophages may enhance or suppress various inflammatory or immune processes in lung, in part, by selective release of various derivatives of arachidonic acid.
Actor-centered Europeanization

Think for a minute about soccer, by the way, the most popular sport in Morocco. How crucial are the rules for the game? Or are the players more important? Well, the game would not exist without the rules, but also could not exist without the players. But what happens if a penalty kick decides what team wins the game, who or what is responsible? Maybe the rule which punished the foul with a free goal kick, or the player who has the nerves to withstand the chanting crowds and scores? Or, was it a bad referee decision or just chance? Similar to soccer, processes of institutional change can be triggered by various factors, from which, selecting the decisive ones, is a puzzling task. What came first, the structure or the person? The answer fills libraries, with some studies concluding the structure determines everything, while others believe people can change everything—but only if it is in their interest.
Effect of Curvature on Carbon Chemical Shielding in Extended Carbon Systems.

The effect of curvature on the chemical shielding of carbons in curved polycyclic aromatic hydrocarbons has been systematically studied by examining structures analogous to the circumcoronene molecule with different degrees of curvature. We attempt to eliminate effects from Knight shifts in carbon nanotubes, differing ring currents from five-membered rings, and edge effects in finite nanotube models in order to separate out the change in shielding that is due to curvature alone. Using curved structures derived from geometry-optimized structures of carbon nanotubes, we calculate the carbon chemical shielding tensor for carbons in the central aromatic ring as well as the Nucleus Independent Chemical Shift (NICS) on the convex and concave side of each structure. All three tensor components become less shielded with increasing curvature of the system, with the σ33 component radial to the curve experiencing the greatest change. The NICS values are influenced by both the decrease in aromaticity as the structure...
Implementation of an Inpatient Electronic Referral System (Opt-to-Quit) From the Electronic Health Record to the New York State Smokers’ Quitline: First Steps

OBJECTIVES: (1) To implement a new policy-driven referral program, Opt-to-Quit, using electronic data transfer from the electronic health record (EHR) to the New York State Smokers’ Quitline (NYSSQL) and (2) to improve referrals to the NYSSQL for smoking caregivers of children admitted to a children’s hospital. METHODS: Smoking caregivers of pediatric patients were referred to the NYSSQL through a standardized template built into the EHR, during the child’s hospitalization or emergency department encounter. Direct data exchange was based on a point-to-point protocol, without dependence on any external centralized processing service. Input and oversight were provided by a multidisciplinary task force, which included physician and nursing leadership, information technology specialists, Health Insurance Portability and Accountability Act compliance personnel and legal counsel, and NYSSQL staff. The process was refined through several iterative plan-do-study-act cycles, using a single-armed, prospective cohort study design, including surveys of nursing staff and continued input of information technology experts on both hospital and Quitline sides. RESULTS: In 2013, 193 smokers were identified in 2 pilot units; 62% (n= 119) accepted referral to the NYSSQL. In 2014, after expansion to all inpatient units and the emergency department, 745 smokers were identified, and 36% (n = 266) accepted referral. Over the 2 years, overall increase in referrals was 124%; as of the first quarter of 2015, referral rate was sustained at 34%. CONCLUSIONS: Hospital-wide implementation of the Opt-to-Quit program through our EHR was feasible and sustainable and has significantly improved referrals to the NYSSQL.
Design factors involved in mechanically coupling electrical machines to driving or driven equipment

The loads to which electrical machines and coupled equipment can be subjected have been described. Appreciation of these loads and an understanding of the torsional characteristics of the coupled system as a whole is essential to the satisfactory performance of the equipment. Modern design aids can assist in identification of possible problem areas in system behaviour and the effects of proposed solutions can be assessed rapidly and effectively. >
Inference for probability of selection with dependently truncated data using a Cox model

ABSTRACTA truncated sample consists of realizations of two variables L and T subject to the constraint L < T. One simple solution to dependently truncated data is to take L as a covariate of T in the Cox model. We aimed at studying the probability of selection, P(L < T), in this framework. We proposed the point estimator and derived its asymptotic distribution. Both truncated-only data and censored and truncated data were generated in the simulation study. The proposed point and variance estimators showed good performance in various simulated settings. The bone marrow transplant registry data were analyzed as the illustrative example.
Countermeasures Against False-Name Attacks on Truthful Incentive Mechanisms for Crowdsourcing

The proliferation of crowdsourcing brings both opportunities and challenges in various fields, such as environmental monitoring, healthcare, and so on. Often, the collaborative efforts from a large crowd of users are needed in order to complete crowdsourcing jobs. In recent years, the design of crowdsourcing incentive mechanisms has drawn much interest from the research community, where auction is one of the commonly adopted mechanisms. However, few of these auctions consider the robustness against false-name attacks (a.k.a. sybil attacks), where dishonest users generate fake identities to increase their utilities without devoting more efforts. To provide countermeasures against such attacks, we have designed a Truthful Auction with countermeasures against False-name Attacks (TAFA) as an auction-based incentive mechanism for crowdsourcing. We prove that TAFA is truthful, individually rational, budget-balanced, and computationally efficient. We also prove that TAFA provides countermeasures against false-name attacks, such that each user is better off not generating any false name. Extensive performance evaluations are conducted and the results further confirm our theoretical analysis.
Counselors’ and Counseling Students’ Attitudes toward Transgender Persons

ABSTRACTIssues related to persons who are transgender have gained large interest in recent years, but discrimination and differential health outcomes for persons who are transgender continue. This article reviewed the 14 existing studies on attitudes toward persons who are transgender, none dealing exclusively with counselors and/or counselors in training. This study involved investigation of those attitudes with a sample of 95 counselors and counselors in training. Findings indicated that counselors tend to have positive attitudes. Greater personal familiarity and multicultural competence as well as being female were associated with more positive attitudes, whereas quantity of diversity training was not related and professional experience was related to more negative attitudes.
Salvage Therapy with Intraoperative Cesium-131 for Recurrent Ovarian Cancer

Recurrent ovarian cancer is considered incurable and the current standard of treatment (surgery and chemotherapy) is palliative. For isolated, localized recurrent tumor, brachytherapy with Cesium-131 is a promising treatment because of its localized radiation yet limited exposure to healthy tissue. Compared to its predecessors, Cs-131 has a very short half-life, allowing for highly localized radiation that decreases toxicity of treatment and convenience for the patient. Our case shows a patient diagnosed with recurrent ovarian cancer metastatic to the right paraaortic odes. The first successful application of Cs-131 brachytherapy was performed with 100% local control without added toxicity. This shows a favorable addition to the current standard of care for highly localized ovarian cancers.
Evaluation of a Novel Field Expedient Musculoskeletal Readiness Screening Tool in an Army Basic Training Population.

ABSTRACT Background: Musculoskeletal injuries present a significant challenge to military readiness accounting for over 29% of ambulatory medical visits and 25 million limited duty days across the U.S. Army. Although U.S. Military Health Systems perform periodic general health and deployment assessments, there is no validated tool to determine when a service member is at increased risk of sustaining a musculoskeletal injury. Method: 292 U.S. Army basic training recruits completed a novel injury screening test called the Musculoskeletal Readiness Screening Tool (MRST). It consisted of six separate physical movements and asked one question regarding perceived risk of personal injury. The injury surveillance period covered the duration of the basic training program lasting from 9 to 20 weeks. An independent t test was performed to assess for differences in composite MRST scores between those who sustained an injury and those who did not. A Receiver Operator Characteristic curve analysis was completed to dete...
Reducing Access to Guns by Violent Offenders

Since the massacre of children and educators in Newtown, Connecticut, in December 2012, public concern and mobilization around the issues of gun violence and regulation has surged, and not only in connection with mass shootings. President Obama called for universal background checks to limit access
Idiopathic intracranial hypertension and autonomic neuropathy as the heralding manifestations of neuro-Behcet’s (P5.312)

Objective: Describe a case of intracranial hypertension (IH) and small fiber autonomic neuropathy preceding other manifestations of Behcet’s syndrome. Background: Behcet’s syndrome is an inflammatory condition of unknown cause that is known to affect peripheral nerves. It has rarely been reported to be associated with increased intracranial pressure. Design/Methods: The clinical and diagnostic course of a patient with Behcet’s syndrome-related autonomic neuropathy and IH is discussed. Results: A 21-year-old woman of Mediterranean descent presented with pulsatile tinnitus (PT) and daily headaches. Fundoscopic exam and visual field testing were normal. Lumbar puncture revealed an opening pressure (OP) of 31 cmH20 with normal CSF analysis. Removal of CSF resulted in resolution of PT and improvement of headaches. Repeat OP measurements were over 30 cm H2O (supine with legs and neck extended). Audiologic testing demonstrated mild right-sided sensorineural hearing loss. Treatment with acetazolamide was initiated. Her symptoms remained resolved so long as this was continued, but recurred at attempts to wean. She developed Raynaud’s phenomenon in her digits. Follow up audiologic testing showed normalization of hearing. She developed recurrent bouts of pericarditis. Separately, she began having episodes of presyncope. Autonomic testing showed delayed orthostatic hypotension, with normal heart rate response to deep breathing and normal responses to Valsalva maneuver. Sudomotor responses were decreased (by QSART) throughout the lower extremity and borderline at the forearm. Plasma catechols were normal while supine with an abnormally low orthostatic norepinephrine increment. Skin biopsy demonstrated abnormally low epidermal nerve fiber density (6.11, normal >6.6). She developed recurrent oral and genital ulcers and intermittent fevers. She denied any prior or current sexual contact. Evaluation for infectious causes was negative. Autoimmune/inflammatory markers and HLA-B51 testing were negative. Due to worsening symptoms of autonomic dysfunction, treatment with intravenous immunoglobulin was initiated. Conclusions: Behcet’s syndrome may be associated with autonomic neuropathies. Additionally, Behcet’s may be associated with IH. Study Supported by: The views expressed are those of the author and do not necessarily reflect the policy or position of the Department of the Navy, Department of the Army, Department of Defense, or the United States Government. Research data derived from an approved Naval Medical Center, Portsmouth, VA, IRB protocol. Disclosure: Dr. Cook has nothing to disclose. Dr. Tagg has nothing to disclose.
Structural consequences of NF-κB inhibition by natural antioxidants: α-lipoic acid and vitamin E

It is conceivable that the use of antioxidants to block NF-κB activation is useful in AIDS therapeutics. Our laboratory concerns on how structures of antioxidants relate to their activities. We show that modifying the anatomy of an antioxidant structure leads to a different behavior in the inhibitory action on TNFα induced NF-κB activation. Understanding such phenomena may lead to accelerated development of effective therapeutic antioxidants. Results from two classes of antioxidants, α-lipoic acid and vitamin E are presented.
The Legal Rights of Mentally Retarded Persons in Twentieth Century America

The United States Supreme Court in 1972 freed a mentally retarded person from lifetime court-ordered confinement. In Jackson v. Indiana [53] the Court accomplished this result by articulating the modest proposition that “due process requires that the nature and duration of commitment bear some reasonable relation to the purpose for which the individual is committed” ([53], p. 738). Jackson, who was a mentally retarded deaf-mute, had been charged with two thefts of small amounts of property. Because of his handicaps, he was found incompetent to stand trial. Without any determination of guilt or innocence he was ordered by the Indiana court to be confined by the Department of Mental Health until “sane” ([53], pp. 717–719). The Supreme Court held that the nature and duration of Jackson’s confinement was so devoid of a legitimating purpose that the confinement was an unconstitutional denial of due process ([53], pp. 736–739).
The Social Determinants of Health in a Community Context: Lessons for Sociological Practice:

Much of the research on the social determinants of health has been done at national or international comparative levels. Findings from these studies highlight the importance of macro social factors...
Fiber-reinforced polymer (FRP) composites in environmental engineering applications

Abstract: This chapter presents dozens of select environmental engineering applications of fiber-reinforced polymer (FRP) composite materials with emphasis on their environmental benefits, followed by discussions on durability of composites. Significance of design codes and specifications in promoting and advancing the applications of FRP composites is addressed. With ever increasing attention toward a sustainable built environment, FRP composites have potential to be selected as a material of choice because of the performance and design advantages of FRPs.
Metering in Electricity Markets

Worldwide, from England to Australia, with many stops in the U.S., electricity markets are being restructured. Although, as pointed out by Considine and Kleit (2001), “proponents of restructuring have a difficult time articulating why restructuring is a good idea,” economists see the principal goal of these restructuring initiatives to be the increase in market efficiency, in both a static and dynamic sense.1 From the point of view of economists, an important facet of restructuring initiatives is thus the creation of markets to serve as resource allocation mechanisms. Markets allocate resources in a decentralized fashion through the use of prices. Prices act as signals for production, consumption, and investment decisions. The success of markets (in terms of efficiency) as resource allocation mechanisms therefore depends on the clear communication of accurate price signals. Economists therefore generally support the increased use of price signals for production, consumption, and investment decicions in electricity markets.
WC3 reassortant vaccines in children.

Bovine rotavirus strain WC3 (P7[5], G6) administered at the 12th passage level was well tolerated clinically in infants and efficiently induced serum virus neutralizing antibody (VNA) with bovine rotavirus G6 specificity. The protective efficacy of WC3 vaccine against all rotavirus disease was inconsistent, varying in four separate trials from 76% to 0%; some selective protection against severe disease was seen in all trials. WC3 reassortants containing the gene for an individual human rotavirus VP7 (G) or VP4 (P) surface antigen were also well tolerated, but preferentially induced VNA to the WC3 parent. Efficacy trials of human G1 VP7 reassortant WI79-9 (P7[5], G1) consistently led to >60% protection against all rotavirus disease. A quadrivalent WC3 reassortant vaccine was developed to contain four separate monovalent reassortants expressing human rotaviruses surface proteins G1, G2, G3, and P1A [8] respectively. In a multicenter trial including 439 infants, this vaccine induced 67.1% protection against all rotavirus disease (defined as positive for rotavirus antigen by ELISA only [p= 16.0, eight cases) occurred only in placebo recipients.
Dynamic Programming and Quadratic Programming for Vehicle Power Management

In this chapter, following the theoretical fundamentals, the applications of dynamic programming (DP) on several HEV types including series, parallel and series–parallel are specifically given. ADVISOR-based simulation results prove that the DP algorithm is capable of finding optimal power which is from the battery to the electric motor and then the power ratio between them. Quadratic programming (QP) is also contained in discussion of this chapter due to its advantages of saving computational time in real-time realization. The power management strategy on basis of QP algorithm for fuel optimization of PHEV is depicted in details.
UNIT 9.1 Overview of Molecular Genetic Diagnosis

This unit describes the two approaches for molecular genetic diagnosis, direct mutation analysis and linkage studies. Direct mutation analysis is possible if the gene responsible for a disorder has been cloned and techniques exist to detect mutations. Genetic linkage analysis is used when polymorphic markers are available that are closely linked to a disease gene but the gene itself has not been cloned, or when it is difficult or impossible to detect mutations in the gene. For direct mutation analysis, the unit offers a review of the types of mutations that can be detected and the strategies that can be employed for their detection. The unit then describes the types of disorders that are best suited for linkage-based analysis and offers guidance for interpreting the data.
Abstract 597: Disruptions in Hepatic Insulin Signaling Reveal an Enterohepatic Signaling Pathway that Regulates the ABCG5 ABCG8 Sterol Transporter and Biliary Cholesterol Secretion

Insulin resistance is associated with increased risk for cholesterol gallstones as well as the development of diabetic dyslipidemia. HDL is the primary cholesterol carrier in the reverse cholestero...