cssi/SciSciGPT-SciSciNet huggingface dataset:
Graphically Modeling Stakeholder Values

This study was designed to give insight into the values considered in environmental policy and illustrate the respondents' personal constructions related to creating policy through the development of a graphic tool. Using both qualitative and quantitative methods, this study anonymously captured the intensity of values currently held by decision makers and tracked changes in values over time. Data were acquired through observations of and interviews with stakeholders in a five-year wetland mitigation bank permitting process at the Galveston District of the U.S. Army Corps of Engineers. The study included public and private sector respondents in both governmental and nongovernmental roles. The resulting representations of professional and personal stakeholders' values can be used as a tool for improving information exchange in policy negotiation and provides insight into the complexity of individual and corporate perceptions of a policy issue.
Porting the GROMACS Molecular Dynamics Code to the Cell Processor

The Cell processor offers substantial computational power which can be effectively utilized only if application design and implementation are tuned to the Cell architecture. In this paper, we examine application characteristics which facilitate efficient use of the Cell processor, and those which present obstacles to it. Moreover, we consider possible solutions designed to mitigate inefficiencies. The target application in our study is the GROMACS molecular dynamics package. We have accelerated the most-often used compute-intensive kernel while maintaining the constraints imposed by the structure of the surrounding program. The significant contribution of this paper is the consideration of the kernel in the context of a complex end-to-end application, with irregular data and code patterns, rather than an isolated kernel code. For this challenging scenario, our results show a 2X speedup versus hand-tuned VMX/SSE code running on high-end PowerPC and x86 uniprocessor machines.
Integrated RF circuits design and packaging in high contrast ceramic-polymer composites

The need for pliable, multifunctional RF circuits has resulted in the search for low-cost, convenient and flexible techniques, such as soft lithography, where a patterned metal design is printed on a desired polymer substrate. Hence, we present a low-cost and effective method for the formation of micro-patterns on a pliable, low-dielectric constant polymer-ceramic composite substrate for manufacturing of a bandpass filter with microtransfer molding technique which will be further extended to the fabrication of a stacked patch antenna design. Through this novel approach of blending microfabrication technology in microwave antenna design and fabrication, various metal patterns can be printed on described composite materials with desired dielectric in easy fabrication steps.
Low side-lobe PVDF element using a space tapered electrode

This article describes an approach to hydrophone element design which results in a beam pattern with a low side-lobe structure. The method used is called space tapering. Space tapering simulates a conventional amplitude taper by varying the spacing of equally sized segments of electrode material. These segments are tied in parallel to produce the element output. Five prototype elements were fabricated on a single sheet of polyvinylidene difluoride (PVDF), two control elements, and three elements with increasing degrees of spatial tapering. The results show that, as the spatial density of the segments increase, the beam pattern approaches the ideal theoretical prediction.
Correlates of Relationship Beliefs: Gender, Relationship Experience and Relationship Satisfaction

The purposes of this study were to (a) assess the role of gender, gender-related personality attributes, age and relationship experience in explaining individual differences in relationship beliefs; (b) test various explanations of gender differences in relationship beliefs; and (c) examine correlates of relationship satisfaction for men and women. Subjects (N = 337), who ranged in age from 19 to 47, completed questionnaires assessing relationship beliefs, gender-related personality attributes, relationship experience, proposed mediators of gender differences in relationship beliefs and relationship satisfaction. Results indicated, first, that men and women differed somewhat in their relationship beliefs, and that both instrumental and expressive personality traits were predictive of relationship beliefs. Relationship experience was also associated with relationship beliefs, although more so for women than men. Second, regression analyses provided evidence regarding various mediators of gender differences...
La llegada del Ciborg Mundano

A number of scholars have attempted to outline both a field of “cyborgology” and a set of dominant concerns and tropes concerning the phenomena of accelerating human-machine hybrids. This article argues that, in contrast to popular conceptions of cyborgs as extreme, posthuman monsters, the cyborg concept can be usefully applied to mundane technologies such as automobiles, and that the proliferation of these “mundane cyborgs” is an important consideration in theorizing the cyborg. The essay offers some definitions and typologies of cyborgs, and applies these to the notion that automobiles are exoskeletons with cyborgian consequences.
Texture development of MgO buffer layers grown by inclined substrate deposition

Biaxially textured magnesium oxide (MgO) films used as template layers for YBa/sub 2/Cu/sub 3/O/sub 7-x/ (YBCO)-coated conductors have been grown efficiently and consistently by inclined substrate deposition (ISD). Further improvement in texture and a decrease in surface roughness were obtained by depositing a homoepitaxial MgO layer on the ISD MgO layer at an elevated temperature and flat angle. The texture of the ISD layer was studied as a function of thickness by X-ray diffraction and scanning and transmission electron microscopy. Surface roughness of the ISD and homoepitaxial layers was investigated by atomic force microscopy. Based on the results, the optimal thickness of the ISD layer was determined.
Rethinking Shielding Theory

The traditional "shielding theory" for the shielding effectiveness of enclosures is examined. It is shown that there can be significant effects which are not included within a simple barrier based theory at high frequencies. It is shown that a 1- dimensional box (using the full Maxwell's equations solution) has 1-D resonances that can significantly affect the accuracy of a barrier based shielding calculation. Treating the enclosure as a resonant cavity with perturbations on the walls is a better approach to the analysis of radiated emissions and radiated susceptibility problems at high frequencies (at and above the first resonance). This has the added advantage of having been worked out quite thoroughly for wave guides and resonant cavities.
A coarse-to-fine disparity energy model with both phase-shift and position-shift receptive field mechanisms

Numerous studies suggest that the visual system uses both phase-and position-shift receptive field (RF) mechanisms for the processing of binocular disparity. Although the difference between these two mechanisms has been analyzed before, previous work mainly focused on disparity tuning curves instead of population responses. However, tuning curve and population response can exhibit different characteristics, and it is the latter that determines disparity estimation. Here we demonstrate, in the framework of the disparity energy model, that for relatively small disparities, the population response generated by the phase-shift mechanism is more reliable than that generated by the position-shift mechanism. This is true over a wide range of parameters, including the RF orientation. Since the phase model has its own drawbacks of underestimating large stimulus disparity and covering only a restricted range of disparity at a given scale, we propose a coarse-to-fine algorithm for disparity computation with a hybrid of phase-shift and position-shift components. In this algorithm, disparity at each scale is always estimated by the phase-shift mechanism to take advantage of its higher reliability. Since the phase-based estimation is most accurate at the smallest scale when the disparity is correspondingly small, the algorithm iteratively reduces the input disparity from coarse to fine scales by introducing a constant position-shift component to all cells for a given location in order to offset the stimulus disparity at that location. The model also incorporates orientation pooling and spatial pooling to further enhance reliability. We have tested the algorithm on both synthetic and natural stereo images and found that it often performs better than a simple scale-averaging procedure.
The Kendrick-Eldering-(Frost) pertussis vaccine field trial

Additional material for this article is available from the James hind Library website [http://www.jameslindlibrary.org], where this article was previously published.
Superoxide Contributes to Development of Salt Sensitivity and Hypertension Induced by Nitric Oxide Deficiency

This study was performed to examine the role of superoxide (O 2 − ) in the development of salt sensitivity and hypertension induced by inhibition of nitric oxide (NO) generation. Male Sprague-Dawley rats were fed with diet containing either normal salt (NS) (0.4% NaCl) or high salt (HS) (4% NaCl). These rats were treated with or without an NO synthase inhibitor, nitro-l-arginine methylester (l-NAME) (15 mg/kg/d) and O 2 − scavenger, tempol (30 mg/kg per day) in the drinking water for 4 weeks. Systolic blood pressure (SBP) was measured by tail-cuff plethysmography and urine collection was performed during the course of experimental periods. At the end of 4 weeks, l-NAME treatment resulted in greater increases in SBP in HS rats (127±2 to 172±3 mm Hg; n=8) than in NS rats (130±2 to 156±2 mm Hg; n=9). Co-administration of tempol with l-NAME markedly attenuated these SBP responses to a similar level in both HS (128±3 to 147±2 mm Hg; n=8) and NS rats (126±2 to 142±3 mm Hg; n=8). Urinary 8-isoprostane excretion (U Iso V) increased in response to l-NAME treatment that was higher in HS (10.6±0.5 to 21.5±0.8 ng/d) than in NS rats (10.8±0.7 to 16.9±0.6 ng/d). Co-treatment with tempol completely abolished these U Iso V responses to l-NAME in both HS and NS rats but did not alter urinary H 2 O 2 excretion rate. The decreases in urinary nitrate/nitrite excretion in response to l-NAME treatment were not altered by co-administration of tempol in both HS and NS rats. These data suggest that enhancement of O 2 − activity during NO inhibition contributes to the development of salt sensitivity that is associated with NO-deficient hypertension.
Make it fresh, make it quick: searching a network of personal webservers

Personal webservers have proven to be a popular means of sharing files and peer collaboration. Unfortunately, the transient availability and rapidly evolving content on such hosts render centralized, crawl-based search indices stale and incomplete. To address this problem, we propose YouSearch, a distributed search application for personal webservers operating within a shared context (e.g., a corporate intranet). With YouSearch, search results are always fast, fresh and complete -- properties we show arise from an architecture that exploits both the extensive distributed resources available at the peer webservers in addition to a centralized repository of summarized network state. YouSearch extends the concept of a shared context within web communities by enabling peers to aggregate into groups and users to search over specific groups. In this paper, we describe the challenges, design, implementation and experiences with a successful intranet deployment of YouSearch.
Postdiction: its implications on visual awareness, hindsight, and sense of agency

There are a few postdictive perceptual phenomena known, in which a stimulus presented later seems causally to affect the percept of another stimulus presented earlier. While backward masking provides a classical example, the flash lag effect stimulates theorists with a variety of intriguing findings. The TMS-triggered scotoma together with “backward filling-in” of it offer a unique neuroscientific case. Findings suggest that various visual attributes are reorganized in a postdictive fashion to be consistent with each other, or to be consistent in a causality framework. In terms of the underlying mechanisms, four prototypical models have been considered: the “catch up,” the “reentry,” the “different pathway” and the “memory revision” models. By extending the list of postdictive phenomena to memory, sensory-motor and higher-level cognition, one may note that such a postdictive reconstruction may be a general principle of neural computation, ranging from milliseconds to months in a time scale, from local neuronal interactions to long-range connectivity, in the complex brain. The operational definition of the “postdictive phenomenon” can be applicable to such a wide range of sensory/cognitive effects across a wide range of time scale, even though the underlying neural mechanisms may vary across them. This has significant implications in interpreting “free will” and “sense of agency” in functional, psychophysical and neuroscientific terms.
Fever After International Travel

Fever in a child after international travel may represent a benign self-limited illness or may be a manifestation of a more severe life-threatening disease. Knowledge of these illnesses is extremely important for a clinician managing a febrile child after travel. This article presents an approach to history taking and evaluation of the febrile child after travel, stressing knowledge of diseases endemic to geographic regions, timing of symptoms, travel exposures, and specific presenting signs and symptoms. The article also discusses in detail some of the more commonly encountered systemic febrile illnesses, including malaria, dengue fever, typhoid fever, rickettsial infections, and leptospirosis.
Consed: A Graphical Tool for Sequence Finishing

Sequencing of large clones or small genomes is generally done by the shotgun approach (Anderson et al. 1982). This has two phases: (1) a shotgun phase in which a number of reads are generated from random subclones and assembled into contigs, followed by (2) a directed, or finishing phase in which the assembly is inspected for correctness and for various kinds of data anomalies (such as contaminant reads, unremoved vector sequence, and chimeric or deleted reads), additional data are collected to close gaps and resolve low quality regions, and editing is performed to correct assembly or base-calling errors. Finishing is currently a bottleneck in large-scale sequencing efforts, and throughput gains will depend both on reducing the need for human intervention and making it as efficient as possible. We have developed a finishing tool, consed, which attempts to implement these principles. A distinguishing feature relative to other programs is the use of error probabilities from our programs phred and phrap as an objective criterion to guide the entire finishing process. More information is available at http:// www.genome.washington.edu/consed/consed. html.
An adaptive QoS routing protocol with dispersity for ad-hoc networks

In this paper, we present the design and simulation of a bandwidth constrained multiple path on-demand routing protocol for ad-hoc networks to support end-to-end quality of service, which is known as the adaptive dispersity QoS routing (ADQR) protocol. We propose a route discovery algorithm to find multiple disjoint paths with longer-lived connections, where each path also specifies associated network resource information. This provides an efficient approach for network resource reservation combined with data dispersion and for route maintenance. A longer-lived path generally involves less route maintenance, resulting in an increase of bandwidth utilization. We propose a route maintenance algorithm to proactively monitor network topology changes, providing an interface to network resource management protocols. We also propose a fast rerouting algorithm to significantly reduce data flow and QoS disruptions. Rerouting is proactively carried out before path unavailability occurs. Simulation results show that ADQR reduces data disruptions and provides end-to-end QoS, by employing efficient route discovery and maintenance mechanisms with network resource information.
Location of childbirth for rural women: Implications for maternal levels of care

Background A recent American Congress of Obstetricians and Gynecologists and Society for Maternal-Fetal Medicine (MFM) consensus statement on levels of maternity care lays out designations that correspond to specific capacities available in facilities that provide obstetric care. Pregnant women in rural and remote areas receive particular attention in discussions of regionalization and levels of care, owing to the challenges in assuring local access to high-acuity services when necessary. Currently, approximately half a million rural women give birth each year in US hospitals, and whether and which of these women give birth locally is crucial for successfully operationalizing maternal levels of care. Objective We sought to characterize rural women who give birth in nonlocal hospitals and measure local hospital characteristics and maternal diagnoses present at childbirth that are associated with nonlocal childbirth. Study Design This was a repeat cross-sectional analysis of administrative hospital discharge data for all births to rural women in 9 states in 2010 and 2012. Multivariate logistic regression models were used to predict the odds of childbirth in a nonlocal hospital (at least 30 road miles from the patient's residence). We examined patient age, race/ethnicity, payer, rurality, clinical diagnoses (diabetes, hypertension, hemorrhage during pregnancy, placental abnormalities, malpresentation, multiple gestation, preterm delivery, prior cesarean delivery, and a composite of diagnoses that may require MFM consultation), as well as local hospital characteristics (birth volume, neonatal care level, ownership, accreditation, and system affiliation). Results The rate of nonlocal childbirth among 216,076 rural women was 25.4%. It varied significantly by primary payer (adjusted odds ratio [AOR], 0.76; 95% confidence interval [CI], 0.68–0.86 for Medicaid vs private insurance) and by clinical conditions including multiple gestation (AOR, 1.82; 95% CI, 1.58–2.1), preterm deliveries (AOR, 2.41; 95% CI, 2.17–2.67), and conditions that may require MFM services or consultation (AOR, 1.28; 95% CI, 1.22–1.35). Rural women whose local hospital did not have a neonatal intensive or intermediate care unit had nearly double the odds of giving birth at a nonlocal hospital (AOR, 1.94; 95% CI, 1.64–2.31). Conclusion Approximately 75% of rural women gave birth at local hospitals; rural women with preterm births and clinical complications, as well as those without local access to higher-acuity neonatal care, were more likely to give birth in nonlocal hospitals. However, after controlling for clinical complications, rural Medicaid beneficiaries were less likely to give birth at nonlocal hospitals, implying a potential access challenge for this population.
Interference detection using time-frequency binary hypothesis testing

The growth in demand for wireless broadband is increasing the instrumental value of characterizing interference in spectral bands of interest. In particular, detection and classification of interference is an important function for mobile ad hoc network (MANET) nodes to optimize performance. In this paper, we propose interference detection and classification techniques for a network that consists of N distributed nodes and a classification center connected to each node by a robust link. Due to the limited capacity of the network connecting these nodes, each node compresses the observed signal into a binary vector that spans time and frequency and provides the bits to a classification center. In turn, the classification center stitches the compressed signals from all nodes into a single structure with characteristics that are exploited to detect and classify. The Kolmorgorov-Smirnov test is proposed for node compression. Furthermore, bounds on theoretical classification performance from finite blocklength coding theory are defined. Finally, we propose a minimum distance method to perform classification.
When Electronic Health Records (EHRs) Talk, Everyone Can Win: Our Experience Creating a Software Link Between Hospital and Radiation Oncology EHRs.

In 2015, Boston Medical Center (BMC) implemented the Epic (Verona, WI) electronic health record (EHR). To integrate oncology services throughout our hospital, the radiation oncology department implemented an interface to transfer radiation oncology treatment data from the record and verify system, ARIA (Varian Medical Systems, Palo Alto, CA) to Epic; this interface is commercially available from Varian, but not widely used. Building an interface between ARIA and Epic had a variety of potential advantages.
Mixture Theory-Based Poroelasticity and the Second Law of Thermodynamics

The decisive word in this postulate is the quantifier all it makes the postulate a restrictive condition on the internal constitutive assumptions that can be imposed on systems of the type under consideration.
User-Generated Content and Stock Performance: Does Online Chatter Matter?

Online chatter can strongly affect companies by boosting or slowing down sales of commented products, and user generated content even affects stock prices. An analysis of almost 350,000 consumer reviews and product ratings for 15 brands on popular websites showed some interesting effects: Having a higher volume of user comments, regardless of their assessment, was a strong indication of an increase in stock prices. The researchers also found negative reviews had a stronger impact than positive reviews. According to the results, negative chatter could erode about $1.4 million from the average market capitalization over the short term and $3.3 million over the 15 days after it appeared. To better estimate the dollar value of the findings, the researchers calculated possible profits for an initial investment of $100 million. They either sold or bought stock on a daily basis depending on the prevailing valence of the chatter from the previous day. The overall gains using this strategy yielded an average annual profit of $7.9 million over the four years in the sample. With this result, the researchers beat the Standard & Poor’s 500 index by 8 % by buying stock on positive chatter and short-selling it after negative chatter.
Science Fiction as Critique of Science Organ Transplantation and the Body

Science fiction is often used as a tool with which to think about actual science. While often this is depicted in terms of imaginary future potential, science fiction has also shown itself to be a ...
Crime and Crime Control in an Age of Globalization: A Theoretical Dissection

This article examines theimpact of globalization on both crime and crimecontrol at the national and global levels. Tomake conceptual sense out of the transformingnature of these activities at the turn of the21st century, a threefold analysis ispresented: (1) an overview of the threetraditional developmental models of crime andcrime control – modernization, world system,and opportunity; (2) a characterization ofcrime and crime control in relationship to themore recently emerging models of globalization;and (3) a discussion of the implications of thedialectical relations between the models ofdevelopment and the models of globalization.Assessments of the models and other provisionalconclusions are drawn based on a survey of bothcrime and crime control in 15 developed,developing, and post-traditional nation-states.
Effects of Venous Ligation on Bone Remodeling in the Canine Tibia

After unilateral hind-limb venous ligation (resection and ligation of the iliac vein) in dogs, the saphenous venous pressure in that limb increased transiently. There also was an increase in tibial periosteal appositional bone growth and a concomitant decrease in endosteal appositional bone growth in the limb. It is suggested that even transient increases in pressure within vessels in and about bone may stimulate increased bone remodeling.
A microRNA biomarker of hepatocellular carcinoma recurrence following liver transplantation accounting for within-patient heterogeneity

Liver cancer, of which hepatocellular carcinoma (HCC) is by far the most common type, is the second most deadly cancer (746,000 deaths in 2012). Currently, the only curative treatment for HCC is surgery to remove the malignancy (resection) or to remove the entire diseased liver followed by transplantation of healthy liver tissue. Given the shortage of healthy livers, it is crucial to provide transplants to patients that have the best chance of long-term survival. Currently, transplantation is determined via the Milan criteria—patients within Milan (single tumor < 5 cm or 2–3 tumors < 3 cm with no extrahepatic spread nor intrahepatic vascular invasion) are typically eligible for transplantation. However, combining microRNA expression profiling with the Milan criteria can improve prediction of recurrence. HCC often presents with multiple distinct tumor foci arising from local spread of a primary tumor or from the oncogenic predisposition of the diseased liver. Substantial genomic heterogeneity between tumor foci within a single patient has been reported; therefore, biomarker development must account for the possibility of highly heterogeneous genomic profiles from the same individual. MicroRNA profiling was performed on 180 HCC tumor samples from 89 patients who underwent liver transplantation at the University of Rochester Medical Center. The primary outcome was recurrence-free survival time, and patients were observed for 3 years post-transplantation. MicroRNA expression profiles were used to develop a biomarker that distinguishes HCC patients at greater risk of recurrence post-transplantation. Unsupervised clustering uncovered two distinct subgroups with vast differences in standard transplantation selection criteria and recurrence-free survival times. These subgroups were subsequently used to identify microRNAs strongly associated with HCC recurrence. Our results show that reduced expression of five specific microRNAs is significantly associated with HCC recurrence post-transplantation. MicroRNA profiling of distinct tumor foci, coupled with methods that address within-subject tumor heterogeneity, has the potential to significantly improve prediction of HCC recurrence post-transplantation. The development of a clinically applicable HCC biomarker would inform treatment options for patients and contribute to liver transplant selection criteria for practitioners.
Effect of ovariectomy and replacement therapy upon thyroxine secretion rate of rat.

Summary1) Effect of ovariectomy and replacement with 1 μg estradiol benzoate (EB) and/or 3 mg progesterone (P) upon daily thyroxine secretion rate (TSR) has been studied in mature rats. 2) Ovariectomy reduces TSR approximately 33% within 2-6 days postcastration. Increasing the interval to approximately 90 days between ovariectomy and TSR determination did not result in a further reduction in TSR. EB alone and with P prevented decrease in TSR following ovariectomy but P alone had no effect. 3) It is suggested that ovariectomy reduces the circulating estrogen level which, in turn. may reduce thyrotropin secretion and, subsequently, lower daily TSR.
Vapor Phase Synthesis of Ti Aluminides and the Interfacial Bonding Effect on the Mechanical Property of Micro-Composites Reinforced by Pyrolized SiC Fibers

Vapor phase processings for manufacturing near-net-shaped composites, continuous fiber reinforced composites or lamellar composite will be hopeful methods. The method for synthesis of TiAl by a magnetron sputtering using a multiple target has been successfully established, and the tensile property of the microcomposite with SiC fibers has been studied. The TiAl produced by a vapor phase processing was evaluated by Auger electron spectroscopy and the x-ray analysis. The tensile strength properties of the SiC/TiAl microcompositesof which the interface bonding was controlled with the powers of sputtering were estimated. The properties of SiC/TiAl microcomposites are decreasing with increasing the sputtering power. The irradiation-cured SiC fiber has better compatibility with TiAl than the oxidation-cured SiC fiber. The strength of the microcomposite has been improved with using a thin C-coated irradiation-cured SiC fiber.
Absence of isolated nodes in inhomogeneous random key graphs

We introduce a new random key predistribution scheme for securing heterogeneous wireless sensor networks. Each of the n sensors in the network is classified into r classes according to some probability distribution μ = {μ1, …, μr}. Before deployment, a class i sensor is assigned Ki cryptographic keys that are selected uniformly at random from a common pool of P keys, for each i = 1, …, r. Once deployed, a pair of sensors can establish a secure communication channel if and only if they have a key in common. We model the topology of this network by an inhomogeneous random key graph. We establish scaling conditions on the parameters P and {K1, …, Kr} so that the this graph has no isolated nodes with high probability. The result is given in the form of a zero-one law with the number of sensors n growing unboundedly large. An analogous result is also conjectured for the property of graph connectivity.
Circular polarization of the CMB: Foregrounds and detection prospects

The cosmic microwave background (CMB) is one of the finest probes of cosmology. Its all-sky temperature and linear polarization fluctuations have been measured precisely at a level of $\ensuremath{\delta}T/{T}_{\mathrm{CMB}}\ensuremath{\sim}{10}^{\ensuremath{-}6}$. In contrast, circular polarization ($CP$) of the CMB has not been precisely explored. The current upper limit on the $CP$ of the CMB is at a level of $\ensuremath{\delta}V/{T}_{\mathrm{CMB}}\ensuremath{\sim}{10}^{\ensuremath{-}4}$ and is limited on large scales. Some of the cosmologically important sources which can induce a $CP$ in the CMB include early Universe symmetry breaking, a primordial magnetic field, galaxy clusters, and Pop III stars (also known as the first stars). Among these sources, Pop III stars are expected to induce the strongest signal with levels strongly dependent on the frequency of observation and on the number, ${N}_{p}$, of the Pop III stars per halo. Optimistically, a $CP$ signal in the CMB resulting from the Pop III stars could be at a level of $\ensuremath{\delta}V/{T}_{\mathrm{CMB}}\ensuremath{\sim}2\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}7}$ in scales of 1\ifmmode^\circ\else\textdegree\fi{} at 10 GHz, which is much smaller than the currently existing upper limits on the $CP$ measurements. Primary foregrounds in the cosmological $CP$ detection will come from the galactic synchrotron emission, which is naturally (intrinsically) circularly polarized. We use data-driven models of the galactic magnetic field, thermal electron density, and relativistic electron density to simulate all-sky maps of the galactic $CP$. This work also points out that the galactic $CP$ levels are important below 50 GHz and is an important factor for telescopes aiming to detect primordial B modes using $CP$ as a systematic rejection channel. In this paper, we focus on a SNR evaluation for the detectability of the Pop III induced $CP$ signal in the CMB. We find that a SNR higher than unity is achievable, for example, with a 10 m telescope and an observation time of 20 months at 10 GHz, if ${N}_{p}\ensuremath{\ge}100$. We also find that, if frequency of observation and resolution of the beam is appropriately chosen, a SNR higher than unity is possible with ${N}_{p}\ensuremath{\ge}10$ and resolution per pixel $\ensuremath{\sim}1\text{ }\text{ }\ensuremath{\mu}\mathrm{K}$ at an observation time of 60 months.
Unique Characteristics of Cohabiters Seeking Therapy

There is limited information on cohabiters presenting for therapy. The authors examined the characteristics of 143 married and 54 cohabiting, young (m = 30.39), Caucasian, couples presenting for therapy. We hypothesized that cohabiters presenting for therapy would be more satisfied and committed than married couples and that they would be similarly emotionally differentiated. We conducted a repeated-measures MANOVA to test the hypothesis. Significant effects between partners and between dyads were found, indicating a difference between clients based on relationship status. Cohabiting clients presented earlier in their relationship and were more satisfied and committed. Cohabiting male partners were less emotionally reactive. Without the institutionalized rules of marriage, cohabiting couples may perceive threats to their relationship earlier than married couples.
Comparison of single-dose antibiotic prophylaxis in uncomplicated transurethral resection of the prostate.

AbstractWe evaluated the necessity for antibiotic prophylaxis in uncomplicated transurethral resection of the prostate. A total of 107 patients was entered into a double-blind, prospective, placebo-controlled, randomized trial. Only 7 patients were excluded because they had positive preoperative urine cultures. All patients received a single dose of either 1gm. cefonicid or saline placebo intramuscularly before surgery. No further antibiotics were administered. Urine cultures were obtained intraoperatively, daily while hospitalized, and at 2 and 4 weeks postoperatively. A growth of 104 organisms constituted a positive urine culture. Postoperative infection rates were statistically significant with 12% (6 of 51) in the cefonicid group and 37% (18 of 49) in the placebo group (p = 0.003). During the initial 2 days postoperatively there were no infections in the cefonicid treated patients as opposed to 8 in the placebo group (p = 0.003). Our study demonstrated the need for antibiotic prophylaxis to prevent in...
TU-H-209-02: Quality Assurance and QMP for Brachytherapy Treatment Delivery and Treatment Planning System.

Learnings Objectives: 1. Although brachytherapy is the oldest form of radiation therapy, the rapid advancement of the methods of dose calculation, treatment planning and treatment delivery pushes us to keep updating our knowledge and experience to new procedures all the time. Our purpose is to present the newest applicators used in Accelerated Partial Breast Irradiation (APBI) and the techniques of using them for a maximum effective treatment. Our objective will be to get the user familiar with the Savi, Contura and ML Mammosite from the detailed description and measurements to cavity eval and choice or size, to acceptance tests and use of each. 2. At the end of the session the attendants will be able to assist at the scanning of the patient for the first treatment, decide on the proper localization and immobilization devices, import the scans in the treatment planning system, perform the structure segmentation, reconstruct the catheters and develop a treatment plan using inverse planning (IPSA) or volume optimization. The attendant should be able to evaluate the quality of a treatment plan according to the ABS protocols and B39 after this session. 3. Our goal is that all the attendants to gain knowledge of all the quality assurance procedures required to be performed prior to a treatment, at the beginning of a treatment day, weekly, monthly and annualy on the remote afterloader, the treatment planning system and the secondary check system. We will provide tips for a consistent treatment delivery of the 10 fractions in a BID (twice daily) regimen.
Endocrine and Metabolic Regulation of Transporters for Organic Cations

The disposition of organic cations in the liver and kidneys are under a dynamic regulation by the endocrine and metabolic systems of the body. Researchers have demonstrated the ability of steroids, sex hormones, and physiological states such as pregnancy to alter the expresion and function of transporter proteins that mediate the uptake and efflux of organic cations. This chapter reviews the endocrine and metabolic pathways that influence the pharmacokinetics as well as the toxicity of organic cations.
Psychotherapie bei Depression – 2. Teil

Die Leitlinie empfiehlt Psychotherapie bei allen Schweregraden der Depression. Sie fasst differenzierte Empfehlungen auf der Grundlage des aktuellen Forschungsstandes zusammen. Je nach Schweregrad und Verlaufsform ist Psychotherapie als Monotherapie oder Kombinationstherapie empfehlenswert. Empirisch bewahrt hat sich ein Modell, das den Patienten moglichst gut informiert und zu gemeinsamen Entscheidungsfindungen als wirksame Initiatoren fur eine tragfahige therapeutische Beziehung fuhrt, deren Effekt sich positiv auf die Behandlungsergebnisse auswirkt.
LEVELS OF OBESITY AND ACCURACY OF THE ATHEROSCLEROTIC CARDIOVASCULAR RISK EQUATION IN A LARGE COMMUNITY-BASED COHORT

Background: The accuracy of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) Pooled Cohort Risk Equation for atherosclerotic cardiovascular disease (ASCVD) events across different levels of obesity is not known. Methods: The target population for consideration of primary
A Novel Sample Preparation for Shotgun Proteomics Characterization of HCPs in Antibodies.

Residual host cell proteins (HCPs) in biopharmaceuticals derived from recombinant DNA technology can present potential safety risks to patients or compromise product stability. Thus, the downstream purification process is designed to demonstrate robust removal of these impurities. ELISA using polyclonal anti-HCP antibodies as reagents for capture, detection, and quantitation purposes is most commonly used to monitor HCP removal during process development, but this technique has limitations. More recently, LC-MS for residual HCP characterization has emerged as a powerful tool to support purification process development. However, mass spectrometry needs to overcome the enormous dynamic range to detect low ppm levels of residual HCPs in biopharmaceutical samples. We describe a simple and powerful methodology to characterize residual HCPs in (monoclonal) antibodies by combining a novel sample preparation procedure using trypsin digestion and a shotgun proteomics approach. Differing from the traditional method...
Rapid Characterization of Local Shape Memory Properties through Indentation.

Shape memory alloys (SMAs) have the ability to show large recoverable shape changes upon temperature, stress or magnetic field cycling. Their shape memory, material and magnetic properties (e.g. transformation temperatures, strain, saturation magnetization and strength) determine their prospects for applications from small-scale microelectromechanical systems to large scale aerospace and biomedical systems. It should be noted that properties of SMAs are highly temperature dependent. Generally, the conventional mechanical characterization methods (e.g, tension, compression, and torsion) are used on bulk samples of SMAs to determine those properties. In this article, it will be shown that indentation technique can be used as an alternative rapid method to determine some of the important shape memory properties of SMAs. Indentation response of a high-temperature NiTiHf alloy was determined as a function of temperature. A clear relationship between the work recoverable ratio and transformation temperatures, superelastic and plastic behavior was observed. This work shows that indentation response can be used to measure local superelasticity response, determine phase transformation temperatures and reveal the temperature intervals of the deformation mechanisms of shape memory alloys.
Is It Well with Your Soul? The Surprising Divide within the Baptist Community Concerning Trinity Lutheran Church of Columbia, Inc. v. Comer

Baptists and Protestants alike are often seen as a monolith. However, there is a rich diversity of opinion concerning separation of church and state amongst notable Baptist institutions, namely, the Ethics & Religious Liberty Commission of the Southern Baptist Convention and the Baptist Joint Committee for Religious Liberty. Contrary to the contentions of the Baptist Joint Committee for Religious Liberty, Trinity Lutheran Church of Columbia, Inc. v. Comer does not undo the centuries of Baptist advocacy for a distinct demarcation between church and state. In fact, Trinity Lutheran’s holding empowers those affiliated with the Baptist faith to engage more meaningfully with their governments and communities-at-large. Further, the Protestant influence has been largely under-appreciated with regards to American governance. Martin Luther and his ilk guided the Founding Fathers to unambiguously delineate the church and state, and the Holy Bible provided instruction concerning the branches of government. Trinity Lutheran shows an appreciation of that history and enshrines a reinvigorated reverence for the American church, specifically churches aligned with the Protestant faith.
Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation.

Nodes of Ranvier and associated paranodal and juxtaparanodal domains along myelinated axons are essential for normal function of the peripheral and central nervous systems. Disruption of these doma...
An Empirical Basis for Forecasting Storm Tides

The storm tides at six coastal stations along northeastern United States produced by eight coastal storms from 1952 to 1956 are compared with significant storm parameters. Tentative forecast graphs of tide versus wind velocity have been developed which indicate that operational usefulness can be achieved by the methods described. The storm tide appears to be a very local phenomenon, dependent primarily upon wind velocity. The problem of storm-tide lag is also examined.
A Practical Guide to the Safety and Monitoring of New IBD Therapies

The therapeutic armamentarium of inflammatory bowel disease is rapidly evolving with the development of novel treatment options including targeted monoclonal antibodies and small molecules. With these new therapies come additional safety and side effect concerns. Infections, malignancies, immunogenicity, and metabolic issues exist for each treatment. Management of these agents in the face of such complications is a challenge clinicians will encounter. In this article, we review the existing safety data behind the monoclonal antibodies and small molecules, suggest appropriate risk stratification and assessment considerations before and during therapy, and make expert recommendations on the management of potential complications or clinical scenarios.
Electromagnetic and Mechanical Design of a Hermetically Sealed Magnetic Gear for a Marine Hydrokinetic Generator

This paper presents a new type of hermetically sealed magnetically geared generator typology for a marine hydrokinetic application. The proposed magnetically geared generator is composed of two series connected magnetic gearbox stages with the second stage having an integrated stator. This paper focuses only on presenting the electromagnetic design for the first stage magnetic gearbox with a 5kW (at 40RPM) rating. A volumetric and mass torque density tradeoff analysis is utilized in order to arrive at a high torque density design. The designed magnetic gearbox uses a unique laminated flux concentration inner rotor and Halbach array outer rotor typology with a 6.67:1 gear ratio. A mechanical deflection analysis is performed to verify that the proposed magnetic gearbox is mechanically robust.
Linking the Getty Vocabularies: The Content Perspective, Including an Update on CONA

This paper focuses on issues surrounding the rich content of the Getty vocabularies, [1] particularly as they have transitioned from more traditional data releases to become optimized for release as LOD and beyond. The Getty vocabularies have been a mainstay of cataloging, indexing, and access for art, architecture, and other cultural heritage information since the 1980s. They are compiled resources that grow through contributions from the expert user community. They are multicultural and multilingual, currently being translated in several languages. With the release of the AAT (Art & Architecture Thesaurus®), ULAN (Union List of Artist Names ®), and TGN (Getty Thesaurus of Geographic Names®) as Linked Open Data (LOD), [2] the Getty vocabularies are entering a new world of seemingly limitless possibilities in digital scholarship. With the addition of new resources, CONA (Cultural Objects Name Authority®) and the Getty Iconography Authority (IA), the Getty vocabularies are poised to truly become linchpins in joining disparate resources from diverse disciplines, including art museums, special collections, libraries, archives, conservation, archaeology, visual resources, universities, and other researchers. The Getty vocabularies may serve as conduits through which data about art, architecture, and other cultural heritage are created and accessed for research and discovery. From their inception, the Getty vocabularies were designed to be linkable to each other and to the broader realm of cultural heritage information. For example, in the AAT, concepts are linked to each other through hierarchical and associative relationships with defined relationship types that inform the user that a rhyta (http://vocab.getty.edu/page/aat/300198841) is a type of ancient drinking vessel having an animal shape and is distinguished from vessels in other cultures having a similar purpose or appearance, such as stirrup cups and sturzbechers. In ULAN, the record for a person such as Katsushika Hokusai (http://vocab.getty.edu/page/ulan/500060426) may include various go names and aliases, and links to records for his teachers, family, and a novelist with whom he collaborated. In TGN, a geographic place record for Siena (http://vocab.getty.edu/page/tgn/7011179) may include ancient names, as well as links to multiple broader hierarchical contexts, for the modern nation of Italy as well as the ancient confederation of states, Etruria. In the IA, an Aztec character Ometecuhtli (http://vocab.getty.edu/page/ia/901002056) may be linked to named legends in which he is a character, as well as to other characters or places to which he is related. In CONA, titles/names and other information for works of art, including architecture, movable works (paintings, sculptures, textiles), and conceptual works (multiples) are linked to AAT, ULAN, TGN, IA and external sources, linking rich information from multiple sources to describe works whether extant, destroyed, or designed but never built. An example is the Old Trikuta temple (http://vocab.getty.edu/page/cona/700002003).
Synthesis of a novel hexaazatriphenylene derivative for the selective detection of copper ions in aqueous solution

A hexaazatriphenylene (HAT) derivative, naphtho[2,3-h]naphtho[2′,3':7,8]quinoxalino[2,3-a]naphtho[2′,3′:7,8]quinoxalino[2,3-c]phenazine-5,10,15,20,25,30-hexaone (NQH) was synthesized, characterized, and found to have novel properties in being selective toward the detection of copper (Cu2+) ions. The capability of NQH to be employed as a colorimetric, chemo-fluorescence and electrochemical sensor for the detection of Cu2+ was demonstrated by performing UV-Vis absorbance, fluorescence intensity, and cyclic voltammetry (CV) measurements. The interaction between NQH and Cu2+ was initially observed with an obvious color change from yellow to brown upon the addition of Cu2+ ions to NQH. The interaction was also confirmed by UV-Vis absorbance, fluorescence intensity, and mass spectroscopy (MS/MS) measurements. UV absorbance, fluorescence and CV of NQH toward Cu2+ showed good linearity with a detection limit of 3.32 μM, 2.20 μM and 0.78 μM, respectively, which are lower than the toxicity levels of copper in drinking water (20–30 μM) set by the U.S. Environmental Protection Agency (EPA) and World Health Organization (WHO). A 1 : 2 stoichiometry complexation between NQH and Cu2+ was confirmed by Job's plot and MS/MS. In addition, the selectivity and sensitivity of the NQH compound towards Cu2+ ions were further confirmed by performing CV on a screen printed flexible and planar electrochemical sensor.