cssi/SciSciGPT-SciSciNet huggingface dataset:
Market Reactions to Warnings of Negative Earnings Surprises: Further Evidence

: This study examines two plausible explanations for Kasznik and Lev's (1995) counterintuitive finding that warning firms are subject to more negative market returns than no-warning firms. Namely, are the more negative market reactions to warning firms due to their poorer future earnings performance or due to investor overreaction? I find that, compared with no-warning firms, warning firms experience more severe one-year-ahead earnings declines and these earnings declines can explain the stronger market returns to warning firms. However, my results do not support an investor overreaction explanation. The tests of subsequent abnormal returns of warning firms over various windows do not detect stock return reversals due to correction for overreaction. In addition, the greater revisions in analysts' forecasts for warning firms are found to enhance analyst accuracy rather than increase analyst pessimism. Collectively, my results suggest that the more negative market reactions to warning firms reflect investors' rational anticipation of more severe declines in future earnings for warning firms rather than investor overreaction.
Ordered Nanowire Array Blue/Near-UV Light Emitting Diodes

[∗] S. Xu , C. Xu , Y. Liu , Y. F. Hu , R. S. Yang , Q. Yang , Prof. Z. L. Wang School of Materials Science and Engineering Georgia Institute of Technology Atlanta, Georgia, 30332–0245 (USA) E-mail: zlwang@gatech.edu J. H. Ryou , H. J. Kim , Z. Lochner , S. Choi , Prof. R. Dupuis School of Electrical and Computer Engineering Georgia Institute of Technology Atlanta, Georgia, 30332–0245 (USA) ZnO-based light emitting diodes (LEDs) have been considered as a potential candidate for the next generation of blue/ near-UV light sources, [ 1 ] due to a direct wide bandgap energy of 3.37 eV, a large exciton binding energy of 60 meV at room temperature, and several other manufacturing advantages of ZnO. [ 2 ] While the pursuit of stable and reproducible p-ZnO is still undergoing, [ 3,4 ] heterojunctions of n-ZnO and p-GaN are employed as an alternative approach in this regard by considering the similar crystallographic and electronic properties of ZnO and GaN. [ 5–7 ] Compared with the thin fi lm/thin fi lm LEDs, [ 5,6 , 8 ] which may suffer from the total internal refl ection, n-ZnO nanowire/p-GaN thin fi lm heterostructures are utilized in order to increase the extraction effi ciency of the LEDs by virtue of the waveguiding properties of the nanowires. [ 9–11 ] But in all of these cases, the n-ZnO nanowires are randomly distributed on the substrate, which largely limits their applications in high performance optoelectronic devices. Here in this work, we demonstrate the capability of controlling the spatial distribution of the blue/near-UV LEDs composed of position controlled arrays of n-ZnO nanowires on a p-GaN thin fi lm substrate. The device was fabricated by a conjunction of low temperature wet chemical methods and electron beam lithography (EBL). The EBL could be replaced by other more convenient patterning techniques, such as photolithography and nanosphere lithography, rendering our technique low cost and capable of scaling up easily. Under forward bias, each single nanowire is a light emitter. By Gaussian deconvolution of the emission spectrum, the origins of the blue/nearUV emission are assigned particularly to three distinct electronhole recombination processes. By virtue of the nanowire/thin fi lm heterostructures, these LEDs give an external quantum effi ciency of 2.5%. This approach has great potential applications in high resolution electronic display, optical interconnect, and high density data storage. The design of the LED is shown in Figure 1a . Ordered ZnO nanowire arrays were grown on p-GaN (Figure 1 b–d), [ 12–14 ]
Rapid de-localization of actin leading edge components with BDM treatment

Background: 2,3-Butanedione monoxime (BDM) has been widely used as a non-muscle myosin inhibitor to investigate the role of non-muscle myosinII in the process of actin retrograde flow and other actin cytoskeletal processes. Recent reports show that BDM does not inhibit any non-muscle myosins so far tested, including nm-myosinII, prompting the question, how were these process affected in BDM studies? Results: We have found that treatment of mammalian cells with BDM for only 1 min blocks actin incorporation at the leading edge in a permeabilized cell system. We show that inhibition of actin incorporation occurs through de-localization of leading edge proteins involved in actin polymerization – the Arp2/3 complex, WAVE, and VASP – that de-localize concomitantly with the leading edge actin network. Conclusion: De-localization of actin leading edge components by BDM treatment is a newly described effect of this compound. It may explain many of the results previously ascribed to inhibition of non-muscle myosinII by BDM, particularly in studies of leading edge dynamics. Though this effect of BDM is intriguing, future studies probing actin dynamics at the leading edge should use more potent and specific inhibitors.
SUPPRESSION OF THE WRAPPING EFFECT BY TAYLOR MODEL- BASED VERIFIED INTEGRATORS: LONG-TERM STABILIZATION BY PRECONDITIONING

The verified integration of ranges of initial conditons through ODEs faces two major challenges, namely the precise representation of the flow over the short term, and the avoidance of unfavorable buildup of errors in the long term. The Taylor model approach is very well suited to overcome the problems of short term flow representation. In this paper we discuss a method based on preconditioning that stabilizes the long-term evolution of the flow. Examples of the performance of the method and comparisons to other approaches are given.
Taurine, hypotaurine, epinephrine and albumin inhibit lipid peroxidation in rabbit spermatozoa and protect against loss of motility.

Loss of forward motility of rabbit epididymal spermatozoa in high K phosphate buffer is in- hibited by taurine, hypotaurine, epinephrine and bovine serum albumin. Pyruvate and lactate also show this effect. The rate of lipid peroxidation in these spermatozoa, as measured by rate of formation of malonaldialdehyde, is also inhibited by these agents. A close linear correlation be- tween percent inert spermatozoa and malondialdehyde was found, which was independent of the rate of peroxidation. Complete cessation of motility was observed at 0.5 nmol malondialdehyde/ iocells in the absence or presence of these agents, which is the same value found in other sus- pending media in a previous study LAlvarez and Storey (1982) Biol. Reprod. 27:1102-11081. Albumin was the most effective agent in preventing loss of motility and inhibiting lipid peroxida- tion. Hypotaurine was the next most effective, followed by taurine, epinephrine, pyruvate and lactate. Hypotaurine reduces the amount of rate of superoxide production, as measured by the rate of reduction of acetylated ferricytochrome c by 0, from rabbit sperm under these conditions and concomitantly reduces inactivation of the superoxide dismutase in these cells. Since superoxide seems to be the major inducer of lipid peroxidation in rabbit sperm, the protective effect of hypo- taurine, which should be readily permeant to the plasma membrane, may be ascribed to scavenging of intracellular superoxide. The mechanism of the protective action of albumin is not known. Rabbit epididymal spermatozoa lose motility over time if Ca2� or Mg2 are omitted from the suspending medium. This loss is not correlated with the rate of lipid peroxidation, which is un- affected by the absence or presence of these ions. The linear correlation between loss of motility and lipid peroxidation no longer holds in the absence of Ca2* and Mg2�, implying motility loss by a different mechanism.
Is it reasonable to deny older patients treatment for glioblastoma

Is it ever fair to limit treatment for diseases like glioblastoma for which prognosis is poor? Because resources are finite and health care spending limits the other possible uses for those resources, limiting access to an intervention that does not generate benefits is ethically sound. Ignoring the balance of benefits and burdens associated with treatment ignores opportunity costs and leads us to treat some lives as more valuable than others. Although it is ethically sound to set limits on medical care, I argue that biological age is a poor criterion for allocating resources.
Taxes, Subsidies, and Advertising Efficacy in Changing Eating Behavior: An Experimental Study

Using a lab experiment with 258 adult non-student participants, we examined whether unhealthy foods taxes, healthy foods subsidies, anti-obesity advertising, and healthy foods advertising have an impact on changing consumers' choices of lunch items and the nutrient content of their choices for a selected meal. A difference-in-difference regression model was used to determine the efficacy of the various policy treatments. The results indicate that the unhealthy foods tax, healthy foods advertising, and unhealthy foods tax combined with anti-obesity advertising significantly reduced the content of some nutrients of concern, such as calories, calories from fat, carbohydrates, and cholesterol in meal selections. We also find that when combined with healthy foods subsidy, the healthy foods advertising has very little effect on nutrient consumption; the anti-obesity advertising on its own, however, is not efficient at changing dietary behavior. We discuss the policy implications of our findings and venues for future research.
Encephalomalacic dysplastic mass lesion associated with vascular abnormalities in an elderly man. Is this "acquired" focal cortical dysplasia?

Focal cortical dysplasia (FCD) is known to occur in association with a principal lesion and has been newly introduced as FCD type III in the ILAE 2011 classification system of FCDs. FCD type IIIc is associated with vascular malformations, and in all such cases in the literature with histologic confirmation, the principal lesion was a cavernous angioma. We present here a case of mass-forming FCD type IIIc with very unusual vasculopathies. The patient, a 75-year-old man, presented with a seizure and left-sided weakness. MRI showed a right frontal intra-axial mass (4 cm in diameter). He had significant multiple cardiovascular risk factors and a history of melanoma and bladder cancer. Craniotomy was performed for excision of the suspected neoplasm. Histologically, the cortex showed transition from normal, laminar cortical architecture to marked architectural abnormality with irregular areas of encephalomalacia, with intervening, almost nodular regions of “preserved” cortex. These regions consisted of large clusters of dysplastic and maloriented neurons. There were medium-sized to larger arteries with marked medial thickening and luminal stenosis, predominantly within the markedly thickened and fibrosed leptomeninges. In addition, the parenchymal vessels showed markedly hyalinized and thickened walls, and several exhibited glomeruloid clusters of new capillaries. We interpreted the cortical and subcortical encephalomalacic features to be presumably “secondary” to the underlying/associated vascular pathology. This case may represent “acquired” FCD. It is possible that this patient had a preexistent cortical dysplasia with secondary ischemic changes; however, given the absence of previous history of seizure, this appears less likely.
Cooperative topology control with adaptation for improved lifetime in wireless ad hoc networks

Topology control algorithms allow each node in a wireless multi-hop network to adjust the power at which it makes its transmissions and choose the set of neighbors with which it communicates directly, while preserving global goals such as connectivity or coverage. This allows each node to conserve energy and contribute to increasing the lifetime of the network. Previous work on topology control has largely used an approach based on considering only the energy costs across links without considering the amount of energy available on a node. Further, previous work has largely used a static approach where the topology is determined at the beginning of the network's life and does not incorporate the varying rates of energy consumption at different nodes. In this paper, we address these weaknesses and introduce a new topology control algorithm that dynamically adapts to current energy levels at nodes. The algorithm, called Cooperative Topology Control with Adaptation (CTCA), employs a game-theoretic approach that maps the problem of maximizing the network's lifetime into an ordinal potential game. This allows a node running the CTCA algorithm to make a sacrifice by increasing its transmission power if it can help reduce energy consumption at another node with a smaller lifetime. We prove the existence of a Nash equilibrium for the game. Our simulation results indicate that the CTCA algorithm extends the life of a network by more than 50% compared to the best previouslyknown algorithm.
Near-Field Imaging of Nonlinear Optical Mixing in Single Zinc Oxide Nanowires

The nonlinear optical response of semiconductor nanowires has potential application for frequency conversion in nanoscale optical circuitry. Here, second- and third-harmonic generation (SHG, THG) are imaged on single zinc oxide (ZnO) nanowires using near-field scanning optical microscopy (NSOM). The absolute magnitudes of the two independent (2) elements of a single wire are determined, and the nanowire SHG and THG emission patterns as a function of incident polarization are attributed to the hexagonal nanowire geometry and (2) tensor symmetry. Semiconductor nanowires are of current interest because of their unique electrical and optical properties. 1-3 In particular, their nonlinear optical properties suggest potential applications as frequency converters or logic/routing elements in nanoscale optoelectronic circuitry. A linear optical property of nanowires, photoluminescence (PL) polarization, has recently been studied in single indium phosphide nanowires. 2 In that case, the PL polarization is based upon the classical electromagnetic properties of a dielectric cylinder and averages ca. 91%. In contrast, coherent nonlinear optical phenomena, such as second- and third-harmonic generation (SHG and THG, respectively), depend explicitly on the crystal lattice structure of the medium, which could yield a very high (nearly 100%) polarization selectivity. In addition, the temporal response of the nonresonant harmonic generation is similar to the pulse width of the pump laser, in some cases 20 fs, 4 while incoherent processes are at least 2-4 orders of magnitude slower. Moreover, nonresonant SHG is essentially independent of wavelength below the energy band gap of semiconductor materials, most often including the 1.3-1.5 Im wavelength region typically used in optical fiber
Modeling collaborative robots for detecting intrusions

In this paper, we study collaborative robots for detecting intrusions using game theory. We consider the coalition formation in a group of three robots which detect and capture intrusions in a closed curve loop. In our analysis model, individuals seek alliances/collaboration if they think their detect regions/lengths are too short to gain an intrusion capturing probability larger enough on their own. We allow coalition seeking to carry an investment cost (c) and let outcomes of parities to be determined by the formation of coalition, with the detect length of a coalition simply to be the sum of those of separate coalition members.
DSP-based real-time video decoding

In this paper we describe the implementation of MPEG4/H.263 real-time video decoding on the high performance fixed-point DSP. This series of DSP utilize a common core based on VelociTI/sup TM/, the advanced very long instruction word (VLIW) DSP architecture, which makes them ideal for the high performance embedded multimedia applications. On the EVM board of this kind of DSP (CPU frequency 160 MHz) we were able to demonstrate decoding of MPEG-4/H.263 bitstream coded at 700 Kbps, CIF (352/spl times/288), at a speed of 55/65 fps, respectively. Applications such as consumer set-top boxes that decode streaming video on the Internet and packet-based videophones will benefit from this performance.
Voiceless implosives in Seereer-Siin

This paper provides articulatory and acoustic data on voiceless implosive stops in Seereer-Siin, an Atlantic language of the Niger-Congo family spoken in Senegal. Seereer is characterized by pairs of voiced and voiceless implosive stops in three places of articulation. These pairs are phonemically contrastive in lexical items. Oral air pressure measurements from Seereer stops uphold Clements & Osu's (2002) proposal that implosives and other non-explosive stops are characterized by the absence of positive oral air pressure rather than the presence of negative oral air pressure during occlusion. Acoustic data show that voiceless implosives are characterized by a short period of silence ranging from approximately twenty to fifty milliseconds before the onset of prevoicing prior to release. These findings replicate to a certain extent those of Faye & Dijkstra (1997).
Freedom, Community and Function: Communitarian Lessons of Medieval Political Theory

The communitarian critique of liberal individualism is presently experiencing something of a decline. One of the reasons for the failure of communitarians to make a lasting impact on liberal theory may be the historical precedents to which communitarians have turned, such as Aristotle and civic republicanism. I argue that communitarian theory may more fruitfully draw upon a model of the relation between individual and community derived from the Latin Middle Ages. This approach—communal functionalism—claims that the community is essentially composed neither of individuals nor of citizens but, rather, of functional groups or parts arranged according to their contribution to the community. I consider two variants of this framework, John of Salisbury's “physiological” version and Marsiglio of Padua's “civic” account. I close with an evaluation of the relevance—and also some of the limitations—of the communal functionalist model in relation to the requirements of contemporary communitarian theory.
A Mössbauer Study on the Clustering and Crystallization Phenomena in BaO-4B2O3 Glasses Containing Dilute Concentrations of Fe2O3

The Mossbauer measurements of the clustering and crystallization phenomena in (1−x) (0.2BaO–0.8B2O3)-xFe2O3, x ≤ 10 mole %, glasses are made in the quenched and heat treated samples. The results indicate that small clusters of two and three iron ions are responsible for the magnetic inhomogeneities observed in the quenched samples. Two superparamagnetic crystalline particles coexist in the heat treated samples whose relative intensities are dependent on the iron concentration and are rather insensitive to heat treating temperatures above 700°C. An epitaxial mode of catalyzed nucleation and crystallization is discussed with reference to the clustering phenomenon and their consecutive developments into crystalline ferrite oxides.
Neutron Scattering Instrumentation: A Tutorial Review

Soon after the discovery of the neutron, by Chadwick in 1932, experiments showed that it, like the electron, had wave as well as particle properties. According to de Broglie's hypothesis, a particl...
Detection of Viral Pathogens by Reverse Transcriptase PCR and of Microbial Indicators by Standard Methods in the Canals of the Florida Keys

In order to assess the microbial water quality in canal waters throughout the Florida Keys, a survey was conducted to determine the concentration of microbial fecal indicators and the presence of human pathogenic microorganisms. A total of 19 sites, including 17 canal sites and 2 nearshore water sites, were assayed for total coliforms, fecal coliforms, Escherichia coli, Clostridium perfringens, enterococci, coliphages, F-specific (F(+)) RNA coliphages, Giardia lamblia, Cryptosporidium parvum, and human enteric viruses (polioviruses, coxsackie A and B viruses, echoviruses, hepatitis A viruses, Norwalk viruses, and small round-structured viruses). Numbers of coliforms ranged from <1 to 1, 410, E. coli organisms from <1 to 130, Clostridium spp. from <1 to 520, and enterococci from <1 to 800 CFU/100 ml of sample. Two sites were positive for coliphages, but no F(+) phages were identified. The sites were ranked according to microbial water quality and compared to various water quality standards and guidelines. Seventy-nine percent of the sites were positive for the presence of enteroviruses by reverse transcriptase PCR (polioviruses, coxsackie A and B viruses, and echoviruses). Sixty-three percent of the sites were positive for the presence of hepatitis A viruses. Ten percent of the sites were positive for the presence of Norwalk viruses. Ninety-five percent of the sites were positive for at least one of the virus groups. These results indicate that the canals and nearshore waters throughout the Florida Keys are being impacted by human fecal material carrying human enteric viruses through current wastewater treatment strategies such as septic tanks. Exposure to canal waters through recreation and work may be contributing to human health risks.
Characterization of directly Compressible Maltodextrins Manufactured by three different Processes

AbstractFive types of maltodextrins which were physically processed by the methods of spray drying, fluidized bed agglomeration, and roller compaction were compared in terms of their pre-, during and post-compaction properties. The maltodextrins all had relatively high moisture contents, and small surface areas. Intrinsic compaction testing found that the maltodextrins all formed stronger tablets than Fast-Flo lactose, and had longer disintegration times which were found to be insensitive to pressure. The roller compacted material had the most fragmentary behavior of the five types of maltodextrins examined. Dissolution testing showed that the maltodextrins had longer release rates than Emdex or Fast-Flo lactose, however the maltodextrin formulations were able to pass a modified USP dissolution test.
Static and High Strain Rate Response of a Glass Fiber Reinforced Thermoplastic

The mechanical response of an impact-modified, discontinuous fiber reinforced styrene-maleic anhydride (S/MA) polymer has been characterized at static and high strain rates and under both dry and wet test conditions. Five different material configurations were tested, including unreinforced S/MA as a reference material and composites incorporating fiber reinforcement with different average diameters, the presence or absence of an interfacial silane coupling agent, and fibers prepared with an acrylonitrile/butadiene latex coating.The ultimate tensile strengths, strains to failure, fracture energies, and effective moduli for each of the materials were evaluated as a function of strain rate, which was varied between 1.67 × 10−3 and 6.0 mm/mm·s. The results of the tests performed on the unreinforced S/MA revealed a 60% increase in the ultimate strength and marked reductions of 80% and 50% in the strain to failure and fracture energy, respectively, with increasing strain rate. While all of the composites exhib...
Microparticle manipulation using multiple untethered magnetic micro-robots on an electrostatic surface

This work presents the control of multiple untethered rectilinear magnetic micro-robots (Mag-μBots) with dimensions 250 × 130 × 100 µm3 actuated by pulsed external magnetic fields, which translate by induced stick-slip motion at speeds of up to 4 mm/s immersed in silicone oil. Multiple Mag-μBot control is enabled by employing an array of individually addressable electrostatic surfaces to selectively anchor individual Mag-μBots. Coupled parallel and uncoupled serial motion of multiple robots is demonstrated, and they can combine to form an assembly that is also capable of motion. Manipulation of 230 µm diameter microspheres is also demonstrated cooperatively by two Mag-μBots in a fluid environment, and is enhanced when the two Mag-μBots are combined. An analysis of the electrostatic anchoring forces and the forces relevant to manipulation is discussed.
Dollars on the Sidewalk: Should U.S. Presidential Candidates Advertise in Uncontested States?

Presidential candidates in the United States do not intentionally advertise in states without rigorous competition for electoral votes. However, in some areas of noncompetitive states, media markets overlap with battleground states, exposing these regions to political ads. These spillover advertisements allow us to examine the relationship between advertisements and individual campaign contributions, with data from the Wisconsin Advertising Project and the Federal Elections Commission. Using propensity-score matching within uncontested states, we find that 2008 aggregate giving in zip codes exposed to political ads was approximately $6,100 (28.1% of mean contributions) more than in similar zip codes without advertisements.
Ultrasonography of the rotator cuff. A comparison of ultrasonographic and arthroscopic findings in one hundred consecutive cases

Background: There has been limited acceptance of shoulder ultrasonography by orthopaedic surgeons in the United States. The purpose of this retrospective study was to determine the diagnostic performance of high-resolution ultrasonography compared with arthroscopic examination for the detection and characterization of rotator cuff tears. Methods: One hundred consecutive shoulders in ninety-eight patients with shoulder pain who had undergone preoperative ultrasonography and subsequent arthroscopy were identified. The arthroscopic diagnosis was a full-thickness rotator cuff tear in sixty-five shoulders, a partial-thickness tear in fifteen, rotator cuff tendinitis in twelve, frozen shoulder in four, arthrosis of the acromioclavicular joint in two, and a superior labral tear and calcific bursitis in one shoulder each. All ultrasonographic reports were reviewed for the presence or absence of a rotator cuff tear and a biceps tendon rupture or dislocation. All arthroscopic examinations were performed according to a standardized operative procedure. The size and extent of the tear and the status of the biceps tendon were recorded for all shoulders. The findings on ultrasonography and arthroscopy then were compared for each parameter. Results: Ultrasonography correctly identified all sixty-five full-thickness rotator cuff tears (a sensitivity of 100 percent). There were seventeen true-negative and three false-positive ultrasonograms (a specificity of 85 percent). The overall accuracy was 96 percent. The size of the tear on transverse measurement was correctly predicted in 86 percent of the shoulders with a full-thickness tear. Ultrasonography detected a tear in ten of fifteen shoulders with a partial-thickness tear that was diagnosed on arthroscopy. Five of six dislocations and seven of eleven ruptures of the biceps tendon were identified correctly. Conclusions: Ultrasonography was highly accurate for detecting full-thickness rotator cuff tears, characterizing their extent, and visualizing dislocations of the biceps tendon. It was less sensitive for detecting partial-thickness rotator cuff tears and ruptures of the biceps tendon.
Current Approaches in Hereditary Nonpolyposis Colorectal Cancer

This article emphasizes the central role of tumor-based testing for microsatellite instability followed by performance of genetic counselor-driven germline mutation testing in hereditary nonpolyposis colorectal cancer (HNPCC). Suitably aggressive colorectal neoplasm surveillance is shown to be critical. Limitations of the evidentiary base for extracolonic screening are conceded, with some cautious suggestions for possible strategies notwithstanding the lack of data. Advances in chemoprevention have been made in both familial adenomatous polyposis (clinical trial data favoring eicosapentaenoic acid) and HNPCC (controversial aspirin data). For various reasons, however, no agent or combination of agents has yet come into routine use in either condition, with further trials underway or being designed for both conditions.
On the Molecular Mechanism of Stabilization of Proteins by Cosolvents: Role of Lifshitz Electrodynamic Forces

Several ionic and nonionic additives are known to affect structural stability of proteins in aqueous solutions. At a fundamental level, the mechanism of stabilization or destabilization of proteins by cosolvents must be related to three-body interactions between the protein, additive, and the water medium. In this study, the role of the Lifshitz–van der Waals electrodynamic interaction between various additives (sucrose, glycerol, urea, poly(ethylene glycol)-200, betaine, taurine, proline, and valine) and bovine serum albumin (BSA) in water medium was examined. The electrodynamic interaction energy was attractive for all of the additives studied here when both far ultraviolet and infrared relaxations of the additives were included in their dielectric susceptibility representations. However, when only the infrared contribution was included for structure stabilizers and both far ultraviolet and infrared contributions for the structure destabilizers, the resulting electrodynamic interaction energy (E/kT) fol...
Wie sagt man ...

This time "Wie sagt man?" will be very short, in dirt bike das Motocrossrad keeping with the theme of "short-order cooking." A (motorized), number of students who work in restaurants have das Mountainbike asked how certain terms are expressed in German. (bicycle) In some cases, there are terms already available in features (of a car, German motorcycle, etc.) die Ausstattung Waiter Kellner game show host der Quizmaster Waitress Kellnerin garage sale der Flohmarkt to wait [tables] bedienen to hold somebody jemanden zur Geisel Tip/gratuity Trinkgeld/Bedienung for ransom nehmen but, as always, terms that refer to specifically hot tub der Whirlpool (wird oft American gastronomical experiences are the ones mit deutschem "i", of interest. Here are some, with no further comalso "Wirlpuhl", ment and in no particular order, short or otherausgesprochen) wise: human services office das PersonalbOro marching band die Marschkapelle waitron plastic jar die Plastikdose, server der Plastikbehalter
Effect of Potassium Fluoride and Pyrethrum on Periplaneta Americana (L.) after Hemocytes Are Blocked with Chinese Ink Or Nephrocytes Are Stained with Trypan Blue

The variation in insect resistance to insecticides is a common phenomenon observed in testing materials for toxicity. Environmental factors, such as temperature, humidity, and diet, have been found to affect resistance, but few attempts have been made to correlate it with physiological conditions within the insect. It is probable, however, that the effect of the environmental factors was to change the physiological state of the insect, which m turn determined its resistance.
Pancreatectomy in Patients with Impaired Renal Function: How Risky Is It?

Chronic renal impairment causes profound physiologic and metabolic changes. Its impact on surgical outcome after pancreatectomy is not well established. We sought to quantify complication rates of pancreatectomy in patients with chronic renal impairment. Database from the American College of Surgeons National Surgical Quality Improvement Project (2005-2011) was queried to identify patients with chronic renal impairment who underwent pancreatectomy. The study population consisted of 16,708 patients of whom 16,649 patients were not on dialysis and 59 patients were on dialysis. Overall mortality for those on dialysis was 5.1 per cent, whereas it was 2.3 per cent for those not on dialysis (P = 0.114). Patients on dialysis were more likely to have failure to wean ventilation (P 2.0 mg/dL. We found the mortality rates for these three groups were 2.0 per cent, 4.6 per cent, and 7.5 per cent, respectively (P < 0.001). In conclusion, need for dialysis is associated with increased postoperative complications. Increased serum creatinine levels were associated with increased mortality rates. These findings should facilitate informative risk/benefit calculation for patients with renal impairment who are considering pancreatectomy.
Teaching Emotional Intelligence in Schools: An Evidence-Based Approach

The skills of emotional intelligence, such as recognizing emotions in the self and others, understanding the causes and consequence of emotions, and effectively regulating the experience and expression of emotional responses, are essential for children’s success in school and life. Yet, many children arrive at school lacking these skills, which can impede them from reaching their full potential. This chapter describes RULER, a Collaborative for Academic, Social, and Emotional Learning (CASEL) SELect approach, to illustrate how the teaching and learning of emotional intelligence can be integrated into the core academic curricula. RULER uses multiple tools to nurture five interdependent skills: recognizing, understanding, labeling, expressing, and regulating emotions. The chapter focuses primarily on emotion regulation skills and on how the tools that RULER uses foster their development. The promise of formative assessments to enhance the teaching and learning of emotional intelligence is also discussed.
Abstract 1530: Dissecting breast cancer dormant CTC phenotypes

Tumor relapse is a clinically relevant problem in breast cancer where patients are asymptomatic because disseminated cells appear to become dormant for periods longer than 20 years and are undetectable by current clinical tools. Uncovering phenotypes of circulating tumor cells (CTCs) - the “seeds” of intractable metastasis-offers the promise to dissect CTC heterogeneity in relation to metastatic competence, to predict biomarker assessment, and to significantly improve monitoring and treatment of cancer. However, little is known about CTC biology and how CTCs differ in their capacity to circulate while maintaining a metastatic potential. We hypothesized that EpCAM-negative breast cancer CTC subsets exist, and avoid organ arrest with extreme efficiency by the concomitant presence of quiescence and stem cell properties. We collected peripheral blood of clinically diagnosed breast cancer patients with or without brain metastasis, and performed multiparametric flow cytometry to isolate EpCAM-negative CTC subsets with stem-cell properties (CD44+/CD24-), along with combinatorial expression of two neoplastic markers: urokinase plasminogen activator receptor (uPAR) and integrin beta1 (int β1). EpCAM-negative CTCs were further interrogated at a single-cell level employing DEPArray platform. Second, we were able to culture FACS-sorted CTC subsets, selected for six cell-surface expression markers (CD45-/EpCAM-negative/CD44+/CD24-/uPAR+/-/int β1+/-), as long-term in-vitro 3D CTC tumorspheres. Third, CTC subsets were interrogated for biomarker profiling and biological characteristics. We identified adhesive, proliferative and invasive properties of 3D CTC tumorspheres which were distinct per uPAR/int β1 combinatorial expression. Lastly, we performed next-generation whole-genome sequencing and mutation analyses to discover unique genomic signatures of uPAR/int β1 CTC subsets and verified as putative CTCs originally disseminated from primary breast tumor. Additional investigations are being pursued assessing the molecular and genomic characterization of uPAR/int β1 CTC subsets comprehensively. Clinical relevance of this research includes that this may enhance abilities to prospectively identify patients who may be at high-risk of developing breast cancer brain metastasis. Citation Format: Monika Vishnoi, Sirisha Peddibhotla, Wei Yin, Zhong Xue, Antonio T. Scamardo, Goldy C. George, David S. Hong, Dario Marchetti. Dissecting breast cancer dormant CTC phenotypes. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 1530.
Reactions to Rituximab in an Outpatient Infusion Center: A 5-Year Review.

Background Reactions to rituximab occur frequently, with up to 77% of patients developing a reaction during initial exposure. The safety of rechallenging patients after a reaction is not clear and standard guidelines are lacking. Objective To better understand clinical decision making surrounding rituximab reactions and subsequent rechallenge. Methods We performed a 5-year retrospective review of all rituximab reactions at a large academic outpatient infusion center. Patients' demographic characteristics, clinical symptoms, and management of reactions were reviewed. Reaction severity was classified using standard criteria. Results Between June 2006 and January 2011, 67 patients (mean age, 58 ± 13 years, 54% men) with at least 1 rituximab reaction were identified. Most reactions occurred during the first exposure to rituximab (63%). Most reactions (n = 59 [88%]) were grade 1 or 2. Fifty-one patients (n = 51 [88%]) were rechallenged with rituximab on the same day as the initial reaction. Most patients with a grade 1 reaction tolerated rechallenge. Conversely, all 4 patients with a grade 3 reaction had a reaction during rechallenge. The outcome of same-day rechallenge after an initial grade 2 reaction was varied; most patients (26 of 31 [84%]) tolerated same-day challenge, but 5 patients had a reaction (all grade 1-2 severity). Conclusions Consistent with previous data, our observations suggest that patients who experience grade 1 reactions to rituximab can be safely rechallenged the same day. A grade 3 or 4 reaction should prompt referral to an allergy specialist for risk assessment before additional rituximab administration. Further research is needed to understand the optimal management of patients with grade 2 reactions.
Emerging Carbon Markets and Fundamentals of Tradable Permits

This chapter discusses the emerging carbon markets and fundamentals of tradable permits. Environmental commodities represent the largest and fastest growing new commodity markets in North America and the world, with a value measured in trillions of dollars. They capture much of the value that society places on safeguard in the environment and energy independence, and are essential to achieving environmental objectives. The increasing involvement of major national and international players, particularly financial institutions, is a clear indication of the importance of environmental commodities. Therefore, the design of compliance and voluntary markets should be based on sound economic principles, and market trust should be established through a national and global technology infrastructure that supports effective markets and their regulatory oversight. This chapter outlines a number of success factors essential in addressing both emission reductions and resulting markets for tradable permits, as well as some of the technological requirements for effective management and regulatory oversight of such markets.
Optimal utilization of power transformers through virtual sensing

Power transformers are the most critical and expensive assets for utility companies and are expected to last for at-least 30-40 years. Unfortunately, many of them have failed before reaching their rated life. In order to prevent such premature failures, utility companies usually deploy real time asset management system by installing thermal sensors (e.g. fiber-optical sensor) inside the tank of large transformers (~500MVA). However, being expensive, sensor deployment may not be commercially viable for small and medium size (<;=250MVA) transformers. This paper proposes an asset management scheme of such power transformers through virtual (sensor-less) sensing. It simulates transformer internal heating phenomena (like hot-spot temperature, insulation aging, loss of life, etc.) using easily available SCADA measurements, ambient temperature from on-line weather forecast, and transformer assets data. It predicts future load and incentive and optimizes transformer operation by analyzing the economic incentive for carrying power and payoff for the loss of life calculated from virtual sensing. Proposed scheme is evaluated and implemented in Fortum's transformers in Finland and experimental results are presented.
Effect of G-CSF and Intramyocardial Injection of Bone Marrow Cells on Cardiac Function in Mouse Model of Myocardial Infarction: A Word for Neo-Vasculogenesis.

Abstract Recent studies suggest that primitive stem cells derived from bone marrow (BM) possess greater functional plasticity that was expected previously. It has been shown that bone marrow stem cells (BMSC) promote repairing mechanisms within myocardium following ischemia/reperfusion models of myocardial infarction (MI). Although it remains unclear whether BMSC transdifferentiate into or just fuse with cardiomyocytes, hemodynamic improvement after intramyocardial BMSC injection as well as after G-CSF injection has been demonstrated. Here, we investigated the contribution of BMSC versus G-CSF administration in myocardial repair following MI. Ten weeks old C57BL/6J mice were irradiated and transplanted with green fluorescent protein (GFP) positive bone marrow cells. Three months later, these mice underwent ligation of left anterior descending branch (LAD) of coronary artery and subsequently divided into three groups. One group (n=7) received G-CSF administration at 200ug/kg for 10 consecutive days. Another group (n=9) was injected with GFP+ marrow cells directly into ischemic heart. The third group was held as control (n=7). One month after coronary ligation we found significant improvement in cardiac function determined as a cardiac output, maximum power and dP/dt, in the G-CSF group compared to control. We evaluated the phenotype of GFP+ cells within myocardium in each treatment group by 488 nm laser-scanning confocal miscroscopy (of whole heart and slides) 35 days after LAD ligation. We found no evidence of myocardial transdifferentiation or cardiomyocyte cell fusion. Instead GFP+ capillaries were present and exclusively located in infarct border zones in both the G-CSF and bone marrow implantation groups, confirmed by anti-factor VIII staining. G-CSF administration and to a lesser extent marrow injection resulted in improved post infarct cardiac function indices. This beneficial effect is not due to transdifferentiation but could be explained by marrow injected or G-CSF mobilized endothelial progenitor cells (EPC) and/or cytokine mediated neo-vasculogenesis.
Load aggregation effect in power grid

In this paper, the issue of data-driven modeling of a single load in a laboratory set-up is confronted with the same data-driven modeling of the same load, but in a real grid environment. As it is argued here, an aggregation effect of all of the loads in a grid endows a single load with grid-characteristics properties in addition to the usual load-specific properties. Topologically, the hidden feedback structure of a bus model reveals that the resulting digraph is strongly connected, meaning that all loads are intertwined in a single system that cannot be decomposed into islands.
Vitamin E Deficiency-Dependent Mortality in Zebrafish Embryos Results from Lipid Peroxidation and Disrupted Energy Metabolism

Vitamin E (VitE), a lipophilic antioxidant, prevents fetal resorption in VitE-deficient pregnant rodents. However, the mechanism for this requirement is unknown. We explored the underlying cause of mortality during developmental VitE deficiency using an embryonic zebrafish model. Adult 5D zebrafish (Danio rerio) fed defined diets without (E-) or with VitE (E+, 500 mg/kg diet RRR-α-tocopheryl acetate) were spawned to obtain E- and E+ embryos, which we evaluated up to 120 hours-post-fertilization (hpf). At 48 hpf E- embryos began showing deformities and >75% were dead or malformed by 120 hpf. Untargeted metabolomics analyses revealed that after 48 hpf E- embryos were depleted of free docosahexaenoic acid (DHA; p=0.002) and had increased levels of oxidized DHA species, including 7- and 10-hydroxy DHAs (each p
Densities and Viscosities at 293.15–373.15 K, Speeds of Sound and Bulk Moduli at 293.15–333.15 K, Surface Tensions, and Flash Points of Binary Mixtures of n -Hexadecane and Alkylbenzenes at 0.1 MPa

The viscosities and densities (293.15–373.15 K), speeds of sound (293.15–333.15 K), surface tensions (room temperature), and flash points were measured for binary mixtures of n-hexadecane and alkylbenzenes (hexylbenzene, octylbenzene, dodecylbenzene), which are components of diesel fuel. Increasing the temperature decreased densities, and excess molar volumes of mixtures were higher for hexylbenzene mixtures than for octylbenzene mixtures and insignificantly different from zero for dodecylbenzene mixtures. The decrease in excess molar volume with increasing alkyl chain length is consistent with other binary mixtures of n-hexadecane and alkylbenzenes. Increasing the temperature decreased viscosities, and the McAllister three-body model successfully modeled viscosity with the compound in the mixture with the highest individual viscosity having the largest fitted interaction parameter. Mixture flashpoints, speed of sounds, bulk moduli, and surface tensions fell between the pure component values. For n-hexade...
Guided deep network for depth map super-resolution: How much can color help?

Since the quality of depth maps produced by Time-of-Flight (TOF) cameras is low, color-guided recovery methods have been proposed to increase spatial resolution and suppress unwanted noise. Despite successful applications of deep neural networks in color image super-resolution (SR), their potential for depth map SR is largely unknown. In this paper, we present a deep neural network architecture to learn the end-to-end mapping between low-resolution and high-resolution depth maps. Furthermore, we introduce a novel color-guided deep Fully Convolutional Network (FCN) and propose to jointly learn two nonlinear mapping functions (color-to-depth and LR-to-HR) in the presence of noise. Experimental results on several benchmark data sets show that our method outperforms several existing state-of-the-art depth SR algorithms. Moreover, this work attempts to partially shed some light onto the fundamental question in color-guided depth recovery — how much can color help in depth SR?
Theories that Combine Many Equivalence and Subset Relations

Knowledge comes in different species, such as equations, contingency tables, taxonomies, rules, and concepts. We show how starting from contingency tables, simple tests can distinguish various special forms of 2-D knowledge. Our experience in data mining with the application of the 49er system shows that the exploration of even a modestly sized database frequently leads to large numbers of regularities. The problem that we address in this paper comes from the recurring observation of users who show serious confusion when faced with thousands of regularities discovered in a database. As a response, 49er uses tests which classify regularities into different categories and applies automated methods which combine large numbers of regularities in each category into concise, useful forms of taxonomies, inclusion graphs and other multi-dimensional theories. We focus on detection of 2-D regularities which can be represented by equivalence and implication relation, and we show how taxonomies and subset graphs can capture large numbers of regularities in those categories. We illustrate the presented algorithms by applications on two databases.