cssi/SciSciGPT-SciSciNet huggingface dataset:
Effect of Pb/Ti Ratio on the Particle Size of Hydrothermal PbTiO3 Powders

The influence of Pb/Ti ratio on the particle size of hydrothermally derived lead titanate (PbTiO3) powders was investigated. Phase pure PbTiO3 powder was synthesized by reacting nanocrystalline TiC2 powder in a 1 m KOH solution for 15 h at 200°C with Pb/Ti ratios of 1 and 5. Faceted platelet particles with a low aspect ratio were formed in solutions with Pb/Ti ratios of 1 and 5. The observed particle size of PbTiO3 was 200 nm and larger when Pb/Ti = 1, while 50 - 100 nm sized particles formed when Pb/Ti = 5. In support of TEM observations, the BET specific surface area data increased from 4.4 m2/g to 7.3 m2/g as the Pb/Ti ratio was increased from I to 5. PbTiO3 particle size was controlled by either inhibiting or promoting dissolution-precipitation. Dissolution-precipitation in a high pH solution was inhibited by maintaining an excess of Pb ions in solution and it was promoted when input concentrations of Pb and Ti were equivalent.
Lipschitz $p$-summing operators

The notion of Lipschitz p-summing operator is introduced. A nonlinear Pietsch factorization theorem is proved for such operators, and it is shown that a Lipschitz p-summing operator that is linear is a p-summing operator in the usual sense.
Is gerontology ready for anti-racist pedagogy? A survey of educators’ practices and perspectives

The older population in the United States is becoming more diverse, bringing increasing attention to the ways in which diversity and multiculturalism are addressed in gerontological education. Although diversity and multiculturalism have long been recognized as important components of the aging experience, our approach to understanding their significance and impact continues to grow and change. Anti-racist pedagogy represents one catalyst to stimulate such change. To evaluate the potential for anti-racist pedagogy in gerontology, this study explored gerontological educators' (N = 121) current practices and perspectives regarding the inclusion of diversity content in their courses, as well as the extent to which they are familiar with and/or use anti-racist pedagogy in their classes. The findings suggest that greater attention to issues of race, ethnicity, and multicultural diversity throughout the gerontological curriculum is needed and wanted. Although respondents were generally unfamiliar with the name anti-racist pedagogy, many indicated that their current teaching practices employed select components of it. Overall, the findings point toward the need for continued exploration of how anti-racist pedagogy may be brought into the gerontological classroom, as well as its implications for future research, policy, and practice.
Synchrony of physiological activity during mother-child interaction: moderation by maternal history of major depressive disorder.

Background Family environment plays an important role in the intergenerational transmission of major depressive disorder (MDD), but less is known about how day-to-day mother–child interactions may be disrupted in families with a history of MDD. Disruptions in mother–child synchrony, the dynamic and convergent exchange of physiological and behavioral cues during interactions, may be one important risk factor. Although maternal MDD is associated with a lack of mother–child synchrony at the behavioral level, no studies have examined the impact of maternal MDD on physiological synchrony. Therefore, this study examined whether maternal history of MDD moderates mother–child physiological synchrony [measured via respiratory sinus arrhythmia (RSA)] during positive and negative discussions. Method Children aged 7–11 years and mothers with either a history of MDD during the child's lifetime (n = 44) or no lifetime diagnosis of any mood disorder (n = 50) completed positive and negative discussion tasks while RSA was continuously recorded for both child and mother. Results Results indicated significant between-dyad and within-dyad group differences in physiological synchrony during positive and negative discussions. Between-dyad analyses revealed evidence of synchrony only among never depressed dyads, among whom higher average mother RSA during both discussions was associated with higher average child RSA. Within-dyad analyses revealed that never depressed dyads displayed positive synchrony (RSA concordance), whereas dyads with a history of maternal MDD displayed negative synchrony (RSA discordance) during the negative discussion and that the degree of negative synchrony exhibited during the negative discussion was associated with mothers' and children's levels of sadness. Conclusions These results provide preliminary evidence that physiological synchrony is disrupted in families with a history of maternal MDD and may be a potential risk factor for the intergenerational transmission of depression.
2009 Influenza A H1N1 influenza epidemic situation in Anshan area laboratory

Objective:Anshan City ILI Influenza H1N1 influenza virus samples for DNA testing for influenza H1N1 flu prevention and control providing the basis.Methods: We collected Anshan region of cases of influenza-like symptoms of 600 throat swabs collected,extracted DNA samples using real-time fluorescent PCR detection kit.Suspected cases were A-/ B-type influenza screening,H1/H3 genotyping,detection of influenza A H1N1,influenza H1N1 detection of discharged patients.Results: 600 suspected cases,a new influenza A H1N1 135 confirmed cases,15 cases of severe cases,2 deaths,patients discharged samples were negative for influenza A H1N1.Conclusion: Laboratory testing for the Anshan area confirmed influenza H1N1 influenza epidemic,prevention and control and treatment of patients provided the basis for the development of laboratory techniques is great significance.
Removing the blinders: utilizing data-plane information to mitigate adversaries in unstructured multicast networks

Numerous collaborative Internet applications, such as video conferencing and broadcasting, have benefited tremendously from multicast services. Multicast overlay networks were proposed as a viable application level multicast architecture to overcome the scarcity of native IP multicast deployments. Many of these networks utilize adaptivity mechanisms to increase performance and provide fault tolerance for end-to-end communication. While pushing functionality to end-systems allows overlay networks to achieve better scalability, it also makes them more vulnerable since end-nodes are more likely to be compromised than core routers. Thus, end-system overlay networks are more vulnerable to malicious inside attacks coming from an attacker or group of colluding attackers that infiltrate the overlay. In particular, attacks that exploit the adaptivity mechanisms can be extremely dangerous because they target the overlay construction and maintenance while requiring no additional communication bandwidth on the attacker side. Such attacks can allow an adversary to control a significant part of the traffic and further facilitate other attacks such as selective data forwarding, cheating, traffic analysis, and attacks against availability. This work presents a solution for mitigating the effect of malicious adversaries on adaptive overlay networks by aggregating and utilizing data-plane and control-plane information to determine the reliability and utility of received information.
Virtual Teams and Outsourcing

The main purpose of this chapter is to provide formidable solutions to a growing dilemma of how teams work in a virtual and global environment. The advent of virtual teams creates another level of complexity for designing and maintaining project teams. It also furthers the value proposition of why project management, in general, is required for successful transformation into a virtual community of workers and supports further justifications for outsourcing application development and product support services. The global effects of digital transformation have accelerated the need to understand how virtual teams operate and share information. Virtual teams also serve as a better way of representing the needs of local communities.
Oral administration of withaferin A inhibits carcinogenesis of prostate in TRAMP model.

// Suman Suman 1 , Trinath P. Das 1 , Jim Moselhy 1 , Deeksha Pal 1 , Venkatesh Kolluru 1 , Houda Alatassi 2 , Murali K. Ankem 1 Chendil Damodaran 1 1 Department of Urology, University of Louisville, KY, USA 2 Department of Pathology, University of Louisville, KY, USA Correspondence to: Chendil Damodaran, email: chendil.damodaran@louisville.edu Keywords: dietary agents, chemoprevention, prostate cancer Received: April 28, 2016 Accepted: June 13, 2016 Published: July 20, 2016 ABSTRACT We previously reported that withaferin A (WA), a natural compound, deters prostate cancer by inhibiting AKT while inducing apoptosis. In the current study, we examined its chemopreventive efficacy against carcinogenesis in the prostate using the transgenic adenocarcinoma of mouse prostate (TRAMP) model. Two distinct sets of experiments were conducted. To determine whether WA delays tumor progression, it was given before cancer onset, at week 6, and until week 44. To determine its effect after the onset of prostate cancer, it was given from weeks 12 to 35. In both strategies, oral administration of WA effectively suppressed tumor burden when compared to vehicle-treated animals. No toxicity was seen in treated animals at gross pathological examination. Western blot analysis and immunohistochemistry of tumor sections revealed that in TRAMP controls, AKT and pAKT were highly expressed while nuclear FOXO3a and Par-4 were downregulated. On the contrary, treated mice showed inhibition of AKT signaling and activation of FOX03a-Par-4-induced cell death. They also displayed inhibition of mesenchymal markers such as β-catenin, vimentin, and snail as well as upregulation of E-cadherin. Because expressions of the angiogenic markers factor VIII and retic were downregulated, an anti-angiogenic role of WA is suggested. Overall, our results suggest that WA could be a promising anti-cancer agent that effectively inhibits carcinogenesis of the prostate.
Some advances on inverse particle transport problems with applications to homeland security, invited

Generally speaking, inverse problems consist of the recovery of coefficients in a domain from data in the domain (invasive inverse problems) and/or data on its boundaries (noninvasive inverse problems). In particle inverse problems, photons (including X-rays), neutrons or both are used. The most commonly found inverse problems include computed tomography/radiography with applications to medical fields, oceanography, homogenization, aerospace engineering, object detection (including special nuclear material, chemical or biological agents) etc [1,2,3]. For instance, tomographic imaging is a non-contact, non-destructive investigation method that provides cross-sectional images of objects from transmission data measured by illuminating the objects from one or more different directions and locations. A set of mathematical techniques reconstruct (i.e., infer) the composition of the interior of the objects from their crosssectional images. The common feature of these so-called inverse problems is that the unknowns are the object material properties and the givens are the data collected when illuminating the object with a known source. Data can be collected inside the object (invasive method) or at its boundaries (noninvasive method). For the purpose of homeland security applications, such as cargo and container screening, we will mostly consider noninvasive inverse problems where measurements are performed at the boundaries of the object under scrutiny. The uniqueness of solutions for such problems is discussed in [5,6]; noninvasive problems have in general no unique solution except in the case of 1-group transport with isotropic of mildly anisotropic scattering (see [6]). An unconstrained optimization approach combined with duality principles was previously devised to solve the noninvasive inverse problem [7]. In this paper, we show equivalence of solutions of the previous unconstrained optimization framework with a more conventional constrained optimization approach. We also provide 1-group 2-D sensitivity studies for a sarin vile hidden in a high scatterer object.
Effect of Patellar Resurfacing on Distal Femoral Replacements: Commentary on an article by Mauricio Etchebehere, MD, PhD, et al.: "Patellar Resurfacing. Does It Affect Outcomes of Distal Femoral Replacement After Distal Femoral Resection?".

In the absence of good evidence, we surgeons base decisions on what we were taught, our experience, and a sense of what we think is best for a particular patient. This is the case when we decide whether to resurface the patella during a distal femoral replacement. I go through this every time I get to the end of a case and the implant representative asks, “Do you want to do the patella?” More often than not I reply “No,” acknowledging that my decision is based not on evidence but on my opinion that it is unlikely to benefit the patient. I was therefore eager to read the paper by Etchebehere et al. and hoped that it would shed some light on this question. The authors completed a very good study comparing the results of distal femoral replacement with and without patellar resurfacing. Interestingly, there was no difference in …
People Reject (Superior) Algorithms Because They Compare Them to Counter-Normative Reference Points

People often choose to use human forecasts instead of algorithmic forecasts that perform better on average; however, it is unclear what decision process leads people to rely on (inferior) human predictions instead of (superior) algorithmic predictions. In this paper, I propose that people choose between forecasting methods by (1) using their status quo forecasting method by default and (2) deciding whether or not to use the alternative forecasting method by comparing its performance to a counter-normative reference point that is often independent of the performance of the default. This process leads people to reject a superior algorithm when (1) the algorithm serves as their alternative forecasting method and (2) the algorithm performs better than their default forecasting method but fails to meet their reference point for forecasting performance. I present the results of five studies that are consistent with this decision process. In Studies 1 through 4, participants were less likely to use a superior algorithm to complete an incentivized forecasting task when they were assigned to a relatively higher performance goal. This behavior persisted when participants recognized that their performance goal did not provide information about the relative performance of their two forecasting options, and even persisted among those participants who believed that the algorithm was the best performing option. Study 5 shows that this pattern of behavior reverses when people are assigned to use an algorithm as their default forecasting method.
EFFECTS OF TOOTLING ON CLASSWIDE DISRUPTIVE AND ACADEMICALLY ENGAGED BEHAVIOR OF GENERAL-EDUCATION HIGH SCHOOL STUDENTS

Considered the opposite of tattling, Tootling is a positive peer-reporting procedure in which students report their classmates’ positive prosocial behavior instead of inappropriate behavior and employs other well-established behavior analytic principles. This study examined the effects of Tootling on students’ behavior in three general-education high school classrooms. Students wrote and then submitted tootles into a marked container. Teachers recorded the number of tootles on publicly posted progress charts, and read a sample of tootles at the end of the class period. An interdependent group contingency procedure was used along with a class goal of the number of tootles needed to earn the class a reward. An A-B-A-B withdrawal design with follow-up found decreases in classwide disruptive behavior and increases in academically engaged behavior across classrooms. Results suggest that Tootling can provide high school teachers a method for positively reinforcing students’ prosocial behavior, and function as a preventative measure against disruptive behavior. Issues related to social validity and directions for future research are discussed.
The lofts of Soho: gentrification, art and industry in New York, 1950–1980

This is an historian’s detailed story of the rise of Soho, New York City’s famed loft district, over a period of three decades, before it became a chic upscale destination. It provides important in...
Can We Talk? Communicating with Clients

This article considers the best methods in which an attorney can communicate with clients simply and clearly, while still providing the necessary information.
Infinitesimal Mechanism Modes of Tensegrity Modules

Tensegrity structures, invented by Snelson in 1948, are a class of truss structures consisting of a continuous set of tension members and a discrete set of compression members [1, 2]. Ingber [3] stated that the assembly pattern of organic structures such as cells, tissues, organs, and animals are described by a universal building rule of self-assembly at different scales based upon geodesic tensegrity. Furthermore, animal mechanisms, including that of humans, do not include any pins or gears that are representative components of machine. Therefore, in order to develop smart deployable structures as well as understand the role of cytoskeleton in cell mechanotransduction, it is necessary to understand infinitesimal mechanism modes of tensegrity modules [4, 5, 6]. The objectives of the paper are to analytically find initial configurations and pre-stress modes for regular truncated octahedral and cubic tensegrity modules and to classify a large number of infinitesimal mechanism modes by conducting modal analyses. In what follows, the static and dynamic characterization procedure proposed by the authors is employed using the same notation as that of [7, 8].
The Evolution and Ecology of Body Size

An organism’s size affects virtually all aspects of its physiology and ecology. There are presently no theoretical models which can explain the broad patterns of shape and functional changes observed; empirical descriptions of these patterns have suffered from a lack of rigor in choice and analysis of data.
Neurological Effects of Callosotomy

Trescher and Ford reported in 1937 on alexia in the left visual field of a patient who had had section of the posterior callosum by Dandy and opined that “special methods of examination are required to demonstrate the essential symptoms.” In spite of this caveat, until Sperry and his colleagues (1953, 1961) had undertaken their studies on the split-brain monkey, the right questions were not asked. Dandy appeared to be ignorant of Trescher and Ford’s observations on his own patient stating that “No symptoms follow its division. This simple experiment at once disposes of the extravagant claims to function of the corpus callosum” (Dandy 1936).
Cheeger Inequality for Infinite Graphs

In this paper we prove the Cheeger inequality for infinite weighted graphs endowed with 'corresponding' measure. This measure has already been developed in the study of tree lattices. Our graphs have finite volumes. A similar theory has already been developed for manifolds of finite volumes.
Symmetry energy constraints from giant resonances: A relativistic mean-field theory overview

Giant resonances encapsulate the dynamic response of the nuclear ground state to external perturbations. As such, they offer a unique view of the nucleus that is often not accessible otherwise. Although interesting in their own right, giant resonances are also enormously valuable in providing stringent constraints on the equation of state of asymmetric matter. With this view in mind, we focus on two modes of excitation that are essential in reaching this goal: the isoscalar giant monopole resonance (GMR) and the isovector giant dipole resonance (GDR). GMR energies in heavy nuclei are sensitive to the symmetry energy because they probe the incompressibility of neutron-rich matter. Unfortunately, access to the symmetry energy is hindered by the relatively low neutron-proton asymmetry of stable nuclei. Thus, the measurement of GMR energies in exotic nuclei is strongly encouraged. In the case of the GDR, we find the electric dipole polarizability of paramount importance. Indeed, the electric dipole polarizability appears as one of two laboratory observables --with the neutron-skin thickness being the other-- that are highly sensitive to the density dependence of the symmetry energy. Finally, we identify the softness of skin and the nature of the pygmy resonance as important unsolved problems in nuclear structure.
Motivation for Gluten-Free Diet Adherence among Adults with and without a Clinically Diagnosed Gluten-Related Illness

Background and Purpose: Historically used as the sole treatment for celiac disease, there has been a substantial rise in popularity of the gluten-free diet (GFD) as both a diet plan and alternative form of medicine in the United States (US). Approximately 1% of the US population suffers from celiac disease, but various reports show 30% to 80% of adults have an interest in, or are currently adhering to, a GFD. This study aimed to understand this disproportion by exploring GFD adherence motivations, in addition to medical diagnoses, within a population of gluten-free followers. Methods. An anonymous, internetbased survey was administered to assess GFD motivations and adherence within the general population (n=99). Results. Of those currently following or who had previously followed a GFD, medical diagnosis was reported by only 28.6% as motivation for GFD adherence, with 60.7% reporting general health motivations, 25.0% reporting weight loss motivations, and 21.4% reporting curiosity. Conclusion. This study supports previous research suggesting that adherence to a GFD may occur for reasons outside of a medical diagnosis. Public health educators should inform individuals about risks and misconceptions associated with GFDs when implementing healthy eating programs for adults without medically diagnosed digestive conditions.
THREE BROKEN VESSELS IN A PERI-PARTUM PATIENT: A RARE CASE OF SPONTANEOUS TRIPLE CORONARY ARTERY DISSECTION

Spontaneous coronary artery dissection (SCAD) has a strong association with pregnancy and connective tissue disorders. A 23YO Female G5P4, presented to ER for severe sub-sternal chest pain, associated with shortness of breath. PMHx was significant for pre-eclampsia. Initial EKG was remarkable for
Chapter 2 – Recognizing, Addressing, and Celebrating Diversity

Publisher Summary Issues of diversity are integral to all discussions of ecosystemic play therapy. The role of individual, group, and systems differences in the onset and eventual resolution of psychopathology is pervasive in the model. This chapter introduces some of the general issues and concepts that are central to integrating diversity effectively into play therapy practice. However, it is believed that these issues are so much more than peripheral. One problem related to the issue of diversity is the variability and emotional and political nature of the terms used in both formal and casual discussions of diversity. Indeed, language and terminology have a major impact on the nature and quality of the discourse. The chapter discusses the various definitions of such terms. It emphasizes that recognizing, addressing, and celebrating diversity should be considered essential elements of all children's play therapy regardless of the reason for the referral. Therapy cannot be optimally effective unless the needs of the individual and of the various systems in which he or she is embedded can be balanced to the betterment of all concerned. To solve problems effectively, the problems should be approached from a wide variety of perspectives. To ensure a continuous supply of rich and varied perspectives, it is essential to maintain and value the cultural differences.
Extracellular vesicles from organoids and 3D culture systems

When discovered, extracellular vesicles (EVs) such as exosomes were thought of as junk carriers and a means by which the cell disposed of its waste material. Over the years, the role of EVs in cell communication has become apparent with the discovery that the nano-scale vesicles also transport RNA, DNA, and other bioactive components to and from the cells. These findings were originally made in EVs from body fluids of organisms and from in vitro two-dimensional (2D) cell culture models. Recently, organoids and other three-dimensional (3D) multicellular in vitro models are being used to study EVs in the context of both physiologic and pathological states. However, standard, reproducible methods are lacking for EV analysis using these models. As a step toward understanding the implications of these platforms, this review provides a comprehensive picture of the progress using 3D in vitro culture models for EV analysis. Translational efforts and regulatory considerations for EV therapeutics are also briefly overviewed to understand what is needed for scale-up and, ultimately, commercialization. This article is protected by copyright. All rights reserved.
Bidirectional, unlike unidirectional transport, allows transporting axonal cargos against their concentration gradient

Even though most axonal cargos are synthesized in the soma, the concentration of many of these cargos is larger at the presynaptic terminal than in the soma. This requires transport of these cargos from the soma to the presynaptic terminal or other active sites in the axon. Axons utilize both bidirectional (for example, slow axonal transport) and unidirectional (for example, fast anterograde axonal transport) modes of cargo transport. Bidirectional transport seems to be less efficient because it requires more time and takes more energy to deliver cargos. In this paper, we studied various models, which differ by the modes of axonal cargo transport (such as anterograde and retrograde motor-driven transport and passive diffusion) as well as by the presence or absence of pausing states. The models are studied to investigate their ability to simulate axonal transport against the cargo concentration gradient. Due to the great lengths of the axons, anterograde transport has to mostly rely on molecular motors, such as kinesins, to deliver cargos synthesized in the soma to the terminal and other active sites in the axon. Retrograde transport can be also motor-driven, in which case cargos are transported by dynein motors. However, retrograde transport can also occur by cargo diffusion. If cargo concentration at the axon tip is higher than at axon hillock, diffusion will move cargo in the retrograde direction. However, for many cargos diffusion is very slow, often negligible, because for large cargos diffusivity is very small. We argue that because bidirectional axonal transport includes both the anterograde and retrograde cargo populations, information about cargo concentration at the axon entrance and at the presynaptic terminal can travel in both anterograde and retrograde directions. This allows bidirectional axonal transport to account for the concentration of cargos at the presynaptic terminal. In unidirectional axonal transport without diffusion, on the contrary, cargo transport occurs only in one direction, and this disallows transport of information about the cargo concentration at the opposite boundary. For the case of unidirectional anterograde transport, this means that proximal regions of the axon do not receive information about cargo concertation in the distal regions. This does not allow for the imposition of a higher concentration at the presynaptic terminal in comparison to the cargo concentration at the axon hillock.
Insights into Modular Polyketide Synthase Loops Aided by Repetitive Sequences

The loops of modular polyketide synthases (PKSs) serve diverse functions but are largely uncharacterized. They frequently contain amino acid repeats resulting from genetic events such as slipped-strand mispairing. Determining the tolerance of loops to amino acid changes would aid in understanding and engineering these multidomain molecule factories. Here, tandem repeats in the DNA encoding 949 modules within 129 cis-acyltransferase PKSs were cataloged, and the locations of the corresponding amino acids within the module were identified. The most frequently inserted interdomain loop corresponds with the updated module boundary immediately downstream of the ketosynthase (KS), while the loops bordering the dehydratase are nearly intolerant to such insertions. From the 949 modules, no repetitive sequence loop insertions are located within ACP, and only 2 reside within KS, indicating the sensitivity of these domains to alteration.
Lyapunov Theorems for Semistability of Discrete-Time Stochastic Systems with Application to Network Consensus with Random Communication Noise

This paper develops Lyapunov and converse Lyapunov theorems for discrete-time stochastic semistable nonlinear dynamical systems expressed by Ito-type difference equations possessing a continuum of equilibria. Specifically, we provide necessary and sufficient Lyapunov conditions for stochastic semistability and show that stochastic semistability implies the existence of a continuous Lyapunov function whose difference operator involves a discrete-time analog of the infinitesimal generator for continuous-time Ito dynamical systems and decreases along the dynamical system sample solution sequences satisfying an inequality involving the average distance to the set of the system equilibria. These results are then used to develop semistable consensus protocols for discrete-time networks with communication uncertainty capturing measurement noise and attenuation errors in the information transfer between agents. The proposed distributed control architecture involves the exchange of information between agents guaranteeing that the closed-loop dynamical network is stochastically semistable to an equipartitioned equilibrium representing a state of almost sure consensus consistent with basic discrete-time thermodynamic principles.
Consequences of Cov-Lite Loans

Recent years have seen a new trend in commercial bank lending—loans with no financial covenants. These covenant light, or cov-lite, loans raise concerns about excessive risk to lenders due to lack of monitoring. In this study, we examine the consequences of cov-lite loans. Focusing on rated, institutional loans, we find that cov-lite loans are more likely to default than loans with financial covenants. Further, we find minimal evidence that investment riskiness is different for cov-lite borrowers but find evidence that cov-lite borrowers have worse future performance than other borrowers. The results collectively suggest a benefit to financial covenants to lenders which is lost when they issue cov-lite loans.
Seroprevalence and Clinical Outcomes of SARS-CoV-2 in Paediatric Patients with Rheumatic Disease.

Objectives Immunosuppressed paediatric patients with rheumatic disease (RD) may be at risk for severe or critical disease related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Data remain scarce on COVID-19 outcomes in paediatric RD patients. The aim of this study is to determine the seroprevalence of SARS-CoV-2 IgG and to describe COVID-19 outcomes in immunosuppressed paediatric RD patients. Methods Patients diagnosed with RD before age 18 and treated with at least one immunosuppressive medication for at least three months were enrolled from a tertiary paediatric rheumatology practice in New York, and also underwent routine SARS-CoV-2 IgG testing from May to November 2020. Five hundred and seventy-one patients were screened and 262 were enrolled. SARS-CoV-2 IgG+ subjects were assessed for symptoms of COVID-19 infection. SARS-CoV-2 PCR results were recorded where available. Demographic, diagnostic, medication, and outcome data were collected. Results Of 262 subjects (186 female), 35 (13%) were SARS-CoV-2 IgG+; 17 (49%) had symptoms suggestive of COVID-19. Of 17 patients who had SARS-CoV-2 PCR testing, 11 (65%) were PCR+; seven of whom were IgG+. Most SARS-CoV-2 IgG+ subjects were not PCR tested. The most common symptoms in IgG+ and/or PCR+ subjects were fever, fatigue, and cough. No SARS-CoV-2 IgG+ or PCR+ subject developed severe or critical COVID-19 or required hospitalisation. Conclusions This is the first report of clinical outcomes of SARS-CoV-2 infection and seroprevalence of SARS-CoV-2 IgG in a large cohort of paediatric RD patients. Most SARS-CoV-2 IgG+ subjects had no symptoms of COVID-19 infection. Symptomatic subjects all had mild COVID-19 symptoms, suggesting that risk of severe or critical COVID-19 in immunosuppressed paediatric RD patients is minimal.
The torn veil : Matthew's exposition of the death of Jesus

1. Introduction 2. Veils in the Old Testament 3. Functionality and identity in the 'veil of the temple' 4. The veil in Second Temple and Rabbinic Judaism 5. Matthew's temple and Jesus' death: hermeneutical keys to the rending of the veil 6. Analysis of the Matthean velum scissum pericope 7. Conclusion: Matthew's velum scissum - retrospect and prospect.
Coming Apart: The State of White America, 1960-2010

From the bestselling author of Lo"sing Ground" and "The Bell Curve," this startling long-lens view shows how America is coming apart at the seams that historically have joined our classes. In "Coming Apart," Charles Murray explores the formation of American classes that are different in kind from anything we have ever known, focusing on whites as a way of driving home the fact that the trends he describes do not break along lines of race or ethnicity. Drawing on five decades of statistics and research, "Coming Apart" demonstrates that a new upper class and a new lower class have diverged so far in core behaviors and values that they barely recognize their underlying American kinship--divergence that has nothing to do with income inequality and that has grown during good economic times and bad. The top and bottom of white America increasingly live in different cultures, Murray argues, with the powerful upper class living in enclaves surrounded by their own kind, ignorant about life in mainstream America, and the lower class suffering from erosions of family and community life that strike at the heart of the pursuit of happiness. That divergence puts the success of the American project at risk. The evidence in "Coming Apart" is about white America. Its message is about all of America.
Symptom Prevalence in the Elderly

Prevalence of reported symptoms was studied in 1927 women and 1140 men over 65 years of age in an ambulatory health screening program. Reports of 28 common symptoms were obtained from a standardized questionnaire completed by participants at the time of their fourth annual visit to the program. A comparison was made of the prevalence of specific symptoms by sex, age, disease states, and drug use patterns. The most common symptoms reported by women were nocturia (80.4%), swollen feet or ankles (30.5%), cold feet and/or legs (28.6%), and irregular heartbeat (23.2%), whereas men complained most often of nocturia (79.8%), irregular heartbeat (24.8%), cold feet and/or legs (23.6%), and tinnitus (23.1%). Women reported a mean of 3.99 symptoms compared with 3.22 reported by men (P less than .0001). In women their was a statistically significant association for most symptoms in subjects reporting the use of medication compared with a group who did not use medication. In men the use of medication was less highly correlated with reports of symptoms. Nearly 100% of participants reported having at least one disease state. The number of symptoms reported was strongly related to the number of disease states, and after adjusting for diseases, women reported more symptoms than men. The best predictor of symptom prevalence was the number of disease states followed by the number of drugs used and then age.
Q-switched Nd:YAG loop laser with a thermal holographic mirror

Summary form only given. By using thermal holographic gratings recorded in slightly absorbing liquids as a mirror with a laser amplifier inside the loop optical scheme offers the possibility to build effective phase-conjugate lasers. We present results of an experimental investigation of Nd:YAG loop laser performance.
Compatibility of furosemide with aminoglycoside admixtures

The compatibility of furosemide with i.v. admixtures containing each of five different aminoglycosides was studied. Admixtures of amikacin 2 mg/ml, gentamicin 1.6 mg/ml, kanamycin 2 mg/ml, netilmicin 1.5 mg/ml, and tobramycin 1.6 mg/ml (as the sulfate salts) were prepared in both 5% dextrose injection and 0.9% sodium chloride injection in minibags. Furosemide injection 4 ml (40 mg) was then added to each admixture, and the admixtures were examined visually and microscopically for precipitate. The macroscopic and microscopic evaluations were repeated 15 minutes and 24 hours after mixing. To simulate Y-site injection of furosemide, furosemide injection 1 ml (10 mg) was added to 1 ml of each aminoglycoside admixture in a syringe. For admixtures in which precipitates formed, the pH was recorded before and after adding furosemide to subsequent admixtures and also after dropwise addition of 1N sodium hydroxide until the precipitate dissolved. Precipitates were identified using spectrophotometric analysis and melting point determinations. Addition of furosemide resulted in a precipitate only in admixtures containing gentamicin sulfate or netilmicin sulfate; the results for the simulated Y-site injection study were the same. Spectrophotometric analysis and melting point determinations revealed that the precipitate was furosemide. Because furosemide precipitates when added to admixtures containing either gentamicin sulfate or netilmicin sulfate in 5% dextrose injection or 0.9% sodium chloride injection, furosemide should be administered separately or the i.v. tubing should be flushed thoroughly before and after administering this drug via a Y-injection site.
Kinetic studies of the gastric H,K-ATPase. Evidence for simultaneous binding of ATP and inorganic phosphate.

The steady state rate of ATP hydrolysis (v) by the gastric H,K-ATPase and the steady state level of phosphoenzyme (E-P) have been measured at 0 and 10 mM KCl; both v and E-P have a nonhyperbolic dependence on the ATP concentration that is consistent with negative cooperativity. The ratio of the rate of hydrolysis to phosphoenzyme (v/[E-P]) was found to vary with the concentration of ATP. Thus, for the rate law v = [E-P].k, k must be a function of the ATP concentration. This requires that ATP be able to bind to E-P or to an enzyme form that occurs after E-P but prior to an irreversible step, such as the loss of inorganic phosphate (Pi). At low ATP concentrations, product inhibition by Pi gives concave downward plots of 1/v against Pi concentration. Pi increases the apparent Km and decreases the apparent Vm. At saturating ATP concentrations, Pi is a noncompetitive inhibitor. These data show that ATP and Pi can bind to the H,K-ATPase simultaneously. They are inconsistent with mechanisms where the binding of ATP and Pi is mutually exclusive.
On the Maintenance of the Large-Scale Quasi-Permanent Disturbances in the Atmosphere

It is proposed that large-scale quasi-permanent flow systems are maintained against dissipative effects by a transfer of kinetic energy from smaller, cyclone-scale, disturbances which have baroclinic energy sources, the processes involved being non-linear and barotropic. To illustrate how such processes can operate, an example is given based on an idealized flow consisting of a limited number of double-Fourier components. DOI: 10.1111/j.2153-3490.1959.tb00052.x
Design parameters and operating characteristics of animal waste anaerobic digestion systems. Dairy cattle

Abstract This second of three papers covers the design parameters and operating techniques developed using numerical dynamic simulation studies for beef feedlot waste. The mathematical model used in this study was described and validated by Hill (1982a). Beef waste simulations were performed at two common operating temperatures: 35°C and 60°C. Four influent VS loading concentrations (42·5, 64, 85 and 106 g litre −1 ) were studied for 35°C and two (85 and 106 g litre −1 ) for 60°C digester temperature. Detention times (DT) studied varied from 5 to 15 days for 35°C operation and 3 to 10 days for 60°C. Design recommendations for beef waste digestion systems at steady-state operation in the mesophilic temperature range are: VS loading of 85 g litre −1 ; T = 40° C and DT of 8 days. In the thermophilic range, the recommendations are: VS loading of 106 g litre −1 ; T = 60° C and DT of 6 days. Volumetric methane productivitity at these operating conditions can be expected to be 2·6 to 2·7 litres of CH 4 litre-day −1 and approximately 4·5 litres of CH 4 litre-day −1 for mesophilic and thermophilic operation, respectively. Start-up and recovery techniques vary slightly because the temperature difference causes the thermophilic operation to have a much faster response time for changing operating conditions. Mimimum DT are 7, 6, and 4 days for 35°C, 40°C and 60°C operation, respectively.
Transportation-Related Volatile Hydrocarbon Source Profiles Measured in Atlanta

Abstract Samples representative of transportation-related hydrocarbon emissions were collected as part of the 1990 Atlanta Ozone Precursor Monitoring Study. Motor vehicle emissions were sampled in canisters beside a roadway in a tunnel-like underpass during periods of heavy traffic. Airport and aircraft emissions were approximated by canister samples obtained at a major airport facility. Three octane grades of gasoline were purchased from six major vendors in Atlanta. Canister samples were prepared using these fuels to approximate the whole gasoline and gasoline vapor composition of the fuels in use during the study. All samples were analyzed by gas chromatography/flame ionization detection (GC/FID) for their hydrocarbon content. Detailed speciated hydrocarbon profiles were developed from this source sampling and analysis program for use in the Chemical Mass Balance (CMB) model. Profiles presented and discussed here represent the hydrocarbon composition of emissions from a roadway, composite headspace gas...
Using wavelets to learn pattern templates

Despite the success of wavelet decompositions in other areas of statistical signal and image processing, current wavelet-based image models are inadequate for modeling patterns in images, due to the presence of unknown transformations (e.g., translation, rotation, location of lighting source) inherent in most pattern observations. In this paper we introduce a hierarchical wavelet-based framework for modeling patterns in digital images. This framework takes advantage of the efficient image representations afforded by wavelets, while accounting for unknown translation and rotation. Given a trained model, we can use this framework to synthesize pattern observations. If the model parameters are unknown, we can infer them from labeled training data using TEMPLAR (Template Learning from Atomic Representations), a novel template learning algorithm with linear complexity. TEMPLAR employs minimum description length (MDL) complexity regularization to learn a template with a sparse representation in the wavelet domain. We discuss several applications, including template learning, pattern classification, and image registration.
Lung tumorigenesis by 1,2-diformylhydrazine in mice.

1,2-Diformylhydrazine was administered in drinking water as a 2% solution to randomly bred Swiss albino mice for life from 6 weeks of age. As a result of treatment, the lung tumor incidence rose from 15 to 96% in females and from 22 to 82% in males. The treatment had no statistically significant effect on the development of other types of tumors. Histopathologically, the neoplasms exhibited the characteristic appearance of adenomas and adenocarcinomas of the lungs.
Near infrared absorption coefficient of molten glass by emission spectroscopy

Emission spectroscopy is applied in the determination of the near infrared spectral absorption coefficient of molten glass. The glass is held in a small horizontal platinum alloy crucible, within an electrically heated cell, optically coupled to a Fourier transform spectrometer. A formula is derived which relates emissivity to absorption coefficient, thickness, and reflectivities for the glass-air and glass-metal interfaces. The reflectivity parameters are determined, in effect, by varying the thickness. Spectral absorption coefficient results are compared with results of transmission spectroscopy. The emission technique is advantageous in that it eliminates the problem of chemical reactions with window materials used in the transmission method, and sample preparation and interfacing to commercially available spectrometers is simplified.
Reassessing the role of medical therapy in the management of hepatic vein thrombosis

Hepatic venous outflow obstruction caused by hepatic vein thrombosis (HVT) is a manifestation of a hypercoagulable state, most commonly a myeloproliferative disorder (MPD). In the past, HVT was thought to have a poor prognosis unless treated surgically with portosystemic shunt or orthotopic liver transplantation (OLT). The aim of this study was to assess whether early diagnosis of the underlying hematologic disorder and institution of appropriate medical therapy have altered outcome. We reviewed the charts of 22 patients with HVT evaluated at our center from January 1986 to January 1995. The median age was 32 years (range, 14 to 59 years). Underlying etiologies were MPD, 13 (polycythemia vera, 8; essential thrombocythemia, 4; undefined, 1); dysfibrinogenemia, 1; anticardiolipin antibody, 1; oral contraceptive use, 3; and idiopathic, 4. All patients had ascites, hepatomegaly, and/or abdominal pain. Two underwent mesocaval shunting, and 1 had a peritoneal-venous shunt. Seven patients, including 1 with a mesocaval shunt, underwent OLT. The median duration of symptoms before transplantation was 6 months (range, 1.5 to 11 months). Six transplant patients are alive on long-term anticoagulation therapy at a mean post-OLT follow-up of 42 months (range, 2 to 77 months), without recurrence. Of 13 patients treated medically, 10 (77%) are alive at a median follow-up of 40 months (range, 17 months to 14 years 8 months), 1 has died, and 2 have been lost to follow-up. In a majority of patients, symptoms improve with prompt treatment of the underlying hematologic disorder, with a favorable long-term prognosis. Patients with decompensated liver disease can successfully undergo OLT with a low risk of recurrence on long-term oral anticoagulation.
Net Protein Utilization and Amino Acid Deficiencies of Glandless Cottonseed Meal

Abstract MORE than twenty years ago Grau (1946) showed that lysine was the first and methionine the second limiting amino acid in the protein of regular cottonseed meal. Work recently reported from this laboratory (Fisher, 1965) indicated that in addition to lysine and methionine the amino acids leucine, threonine and isoleucine were also and equally limiting for optimum growth of chicks receiving regular cottonseed meal. Yet even when sufficient quantities of all five amino acids were added to cottonseed meal, its net protein utilization value (N.P.U.) was still much inferior to the value obtained for methionine-supplemented soybean meal (Fisher et al., 1962). In the present study, experiments were carried out with a glandless ariety of cottonseed meal produced in Texas, and processed at Texas A & M University. Under conditions similar to those previously employed with regular cottonseed meal, the glandless variety gave far superior N.P.U. values than the regular meal,…