cssi/SciSciGPT-SciSciNet huggingface dataset:
Waveguiding without a waveguide: Local‐mode exciton polaritons in multiple quantum wells

Exciton polaritons are considered in infinite multiple quantum wells which are periodic except that one well (impurity) has a different well width from the others (host). Under certain circumstances it is possible to have a long‐lived exciton‐polariton mode localized about the impurity. From the viewpoint of the electromagnetic field, this corresponds to waveguide modes in the vicinity of an exciton resonance in such structures.
Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters

Two commonly used promoters to ubiquitously express transgenes in zebrafish are the Xenopus laevis elongation factor 1 α promoter (XlEef1a1) and the zebrafish histone variant H2A.F/Z (h2afv) promoter. Recently, transgenes utilizing these promoters were shown to be silenced in certain adult tissues, particularly the central nervous system. To overcome this limitation, we cloned the promoters of four zebrafish genes that likely are transcribed ubiquitously throughout development and into the adult. These four genes are the TATA box binding protein gene, the taube nuss-like gene, the eukaryotic elongation factor 1-gamma gene, and the beta-actin-1 gene. We PCR amplified approximately 2.5 kb upstream of the putative translational start site of each gene and cloned each into a Tol2 expression vector that contains the EGFP reporter transgene. We used these four Tol2 vectors to independently generate stable transgenic fish lines for analysis of transgene expression during development and in the adult. We demonstrated that all four promoters drive a very broad pattern of EGFP expression throughout development and the adult. Using the retina as a well-characterized component of the CNS, all four promoters appeared to drive EGFP expression in all neuronal and non-neuronal cells of the adult retina. In contrast, the h2afv promoter failed to express EGFP in the adult retina. When we examined EGFP expression in the various cells of the blood cell lineage, we observed that all four promoters exhibited a more heterogenous expression pattern than either the XlEef1a1 or h2afv promoters. While these four ubiquitous promoters did not express EGFP in all the adult blood cells, they did express EGFP throughout the CNS and in broader expression patterns in the adult than either the XlEef1a1 or h2afv promoters. For these reasons, these four promoters will be valuable tools for expressing transgenes in adult zebrafish.
A New Tool for Climatic Analysis Using the Köppen Climate Classification

Abstract The purpose of climate classification is to help make order of the seemingly endless spatial distribution of climates. The Koppen classification system in a modified format is the most widely applied system in use today. This system may not be the best nor most complete climate classification that can be conceived, but it has gained widespread application and acceptance during the century since it was introduced. Koppen's classification system is applicable to global climate classification. The authors’ experience shows students struggle with temperature and precipitation distribution and applying these data to the several combinations of descriptive letters in the Koppen system. The authors’ students have successfully utilized the dichotomous key introduced in this article for several years. It seems to overcome the aforementioned problems and simplifies the overall classification process.
Spirituality and religion in group counseling: A literature review with practice guidelines.

There has been increased discussion of the need to attend to clients spirituality and religion as a part ofthe counseling process, but much of the literature to date has focused on individual counseling. How dothe research and resulting practice implications apply to group counseling? This article provides arationale for attending to spirituality and religion in counseling, explores the opportunities and barriersin attending to spirituality and religion in group counseling, and reviews the literature on the growingnumber of group interventions with a spiritual or religious focus. The article ends with specific guidelinesfor when and how to incorporate spirituality and religion into group counseling.Keywords: spirituality, religion, group counseling, group therapy
Myelofibrosis involving lymph node: A novel cytogenetic abnormality in a mimicker of mesenchymal neoplasm

A case of primary myelofibrosis involving lymph node and with a novel cytogenetic abnormality [del (18) (p11.2-3)] is reported. The abnormalities are identical among specimens from the lymph node, peripheral blood, and bone marrow that were analyzed years apart. Additionally, we show that the infiltrate by dysplastic megakaryocytes in the lymph node morphologically mimics a metastatic mesenchymal neoplasm, even when the clinical history myelofibrosis was known.
VASCULAR PLANTS FIRST DESCRIBED IN RYDBERG'S FLORA OF COLORADO

Types are indicated for 28 new names inadvertently published in Rydberg’sFlora of Colorado. Included are a discussion as to the validity of these new names and an explanation of the causes of this oversight. A lectotype ofLupinus decumbens var.argentatus is herein designated by Rupert C. Barneby.
Retinomorphic vision systems

The new generation of silicon retinae has two defining characteristics. First, these synthetic retinae are morphologically equivalent to their biological counterparts-at an appropriate level of abstraction. Second, they accomplish all four major operations performed by biological retinae using neurobiological principles: (1) continuous sensing for detection, (2) local automatic gain control for amplification, (3) spatiotemporal bandpass filtering for preprocessing, and (4) adaptive sampling for quantization. The author introduces the term retinomorphic to refer to this subclass of the neuromorphic electronic systems. Their design principles are compared and contrasted with the standard practice in imager design. It is argued that neurobiological principles are best suited to perceptive systems that go beyond reproducing the dynamic scene, like a conventional video camera does, to extracting salient information in real time. The results from a fully operational retinomorphic vision system are presented and the trade-offs involved in its design are discussed.
Reversal by [d-Ala2,d-Leu5]enkephalin of the dopamine transporter loss caused by methamphetamine

Abstract A single administration of 40 mg/kg (i.p.) of methamphetamine caused a loss of dopamine transporter in the striatum of albino Swiss (CD-1) mouse for at least 3 weeks. The administration of a single dose of [ d -Ala2, d -Leu5]enkephalin (DADLE) (18 mg/kg, i.p.), given at day 14 after the administration of methamphetamine, caused a significant, transient restoration of dopamine transporter level in the striatum. These results suggest that δ-opioid peptide DADLE is able to reverse the neuronal damage caused by methamphetamine.
A Recombinant Form of the Catalytic Subunit of Phosphorylase Kinase That Is Soluble, Monomeric, and Includes Key C-Terminal Residues

Abstract Residues 302–326 of the catalytic (γ) subunit of phosphorylase kinase (PhK) may comprise an autoinhibitory, pseudosubstrate domain that binds calmodulin. To study this, the cDNA corresponding to rabbit muscle PhKγ was expressed using Escherichia coli. This yielded two stable, high-activity PhKγ forms (35 and 42 kDa by SDS–PAGE) that were smaller than an authentic sample of rabbit muscle PhKγ (45 kDa by SDS–PAGE). Each recombinant form was purified to homogeneity. The N-terminal sequence of the larger, 42-kDa form (pk42) matched that of the rabbit muscle enzyme. This suggested that pk42 consisted of PhKγ residues 1–362, including the putative calmodulin-binding, autoinhibitory domain. Kinetic parameters obtained for pk42 were like those previously reported for the intact γ subunit. This implied that the lack of 25 PhKγ C-terminal residues did not affect phosphorylase kinase activity, but greatly improved enzyme stability. An additional 60 residues were removed from the C-terminus of pk42 using the protease m-calpain. This increased the kinase activity 1.5-fold. Consistent with this, the activity of a mutant PhKγ that consisted of residues 1–300, denoted γ1–300, was like that of the m-calpain-treated enzyme. Therefore, although the effect was small, some influence by the C-terminus of pk42 was noted. Moreover, when pk42 was incubated with ATP alone, a C-terminal threonine residue became phosphorylated. Although the influence of this autophosphorylation cannot be inferred from this data, it was evidence that the C-terminus accessed the enzyme's active site. Taken together, these data imply that pk42 will be useful to study phosphorylase kinase structure/activity relationships.
Some static and dynamic problems concerning non-linear behavior of plates and shallow shells with discontinuous boundary conditions☆

Abstract Berger's field equations are generalized to dynamic phenomena in anisotropic plates and shallow shells the anisotropy being either of a cylindrically orthotropic or rectilinearly orthotropic type. Under the assumption that the rim of the structure is prevented from inplane motions explicit equations for the coupling parameter are given. Method of solution in the dynamic case is illustrated by an example involving isotropy and original axial symmetry of the structure. It is shown that for the non-linear oscillations of built-in circular plates a close agreement is reached with the results obtained by means of the Von Karman field equations and a different coordinate function. The procedure suggested for solution of dynamic problems associated with the discontinuities of the boundary conditions is discussed and illustrated on an isotropic case involving a circular plate partially simply supported and partially clamped at the periphery. A numerical example is given concerning static behavior of an infinite isotropic strip uniformly loaded and simply supported along the edges except for two symmetrically situated built-in segments. The dependence of the average moment of clamping on the width of the built-in segments as well as on the load intensity for a fixed width of the segments is displayed on graphs.
Modelling macromolecular diffusion through a porous medium

Abstract The diffusion of large spherical molecules through a porous medium is studied by means of a two-dimensional computer model developed previously [Int. J. Thermophys., 9 (1988) 1061]. For two well-characterized, bimodal, pore size distributions, a random walk procedure is used to determine the diffusivity under several conditions of wall-molecule interaction, represented by a residence time, and pore connectivity, or turtuosity. To simulate a driving force on the molecules, a constant bias in one direction is imposed on the random walk. The unbiased case is also studied. Pore sizes are chosen either at random from each distribution or from one distribution at a time to form a layered structure. The selectivity of the diffusion with respect to molecular size is monitored. The wall-molecule interaction and the molecule size both have an important effect on diffusion, as expected. The arrangement of the pore size distributions, whether in layers or at random, has only a small effect.
Fundamental equilibrium exchange rates and exchange rate dynamics

This paper examines whether there is a tendency for actual exchange rates to return to their fundamental equilibrium exchange rates (FEERs) when the latter are estimated based on popular exchange rate models. Co-integration tests and unit root tests are applied. There is little evidence that the exchange rates of Japan and Germany have a reversion to the purchasing-power-parity (PPP) rates or Williamson's FEERs or the underlying external and internal balance (UEI) FEERs.
Use of Time-Accurate CFD for Inlet-Fan Interaction

The Compressor Aerodynamics Research Laboratory at Wright-Patterson Air Force Base is currently investigating, experimentally and numerically, the effects of inlet distortion on transonic fan performance. The experimental investigation will quantify the flowfield for a cold-tested diffuser-fan with distortion screens, and a coupled diffuser-fan system. Each of these experiments will be mirrored numerically using the solver TURBO. The primary research goal of the work is to quantify the physical mechanisms for distortion-transfer and develop reduced-order models to account for performance and stall-margin loss in engine design. As inlet geometries become more aggressive, namely having smaller length to diameter ratios, the secondary flow physics induce potentially-harmful distortion at the engine fan face. The effects of distortion are typically only investigated experimentally, and at too low a temporal and spatial resolution to adequately quantify the mechanisms which attenuate or amplify total pressure and total temperature non-uniformities. Because of the imbalance of operating conditions between different passages of the turbo-machine, adverse effects have been noted on stall-margin which cannot be explained with traditional design methods. Recently large-scale simulations have been used to investigate total pressure distortion patterns on several full-annulus, multi-stage fan configurations. The current effort simulates a distortion-producing inlet coupled with a single-stage fan. This allows distortion of total pressure, total temperature, and flow angularity to be investigated. Preliminary numerical results have been obtained on the US Air Force Research Laboratory DoD Supercomputing Resource Center (AFRL DSRC) SGI Altix 4700 system for the coupled diffuser-fan system. Total pressure and temperature exhibit both a distinct circumferential variation and a counter-rotation shift. As the simulations are analyzed, a greater understanding of performance detriment, stall-inception, and distortion- transfer in an installed aircraft system will be gained. Finally, a brief discussion of continued efforts investigating blade-row interactions will be presented.
Organisational Learning and Leadership: On Metaphor, Meaning Making, Liminality and Intercultural Communication.

This article discusses sensemaking as a broad framework for understanding organisational learning and its implications for leadership in a global context. Organisational metaphors, the concept of liminality and understanding organisations as interpretation systems are presented as possibilities for enhancing intercultural communication within organisations. The article concludes by identifying challenges and how to overcome them, and raises questions for future dialogue and action.
Randomized non-inferiority trial to compare trimethoprim/sulfamethoxazole plus rifampicin versus linezolid for the treatment of MRSA infection

Objectives: The therapeutic arsenal for MRSA infections is limited. The aim of this study was to assess the noninferiority of a combination of trimethoprim/sulfamethoxazole plus rifampicin versus linezolid alone for the treatment of MRSA infection. Methods: We conducted a randomized, open-label, single-centre, non-inferiority trial comparing trimethoprim/ sulfamethoxazole (160 mg/800 mg three times daily) plus rifampicin (600 mg once a day) versus linezolid (600 mg twice a day) alone in adult patients with various types of MRSA infection. Patients were allocated 1:1 to either regimen. The primary outcome was clinical cure at 6 weeks after the end of treatment (non-inferiority margin 20%) assessed by both ITT and PP analyses. Secondary outcomes included the microbiologically documented persistence of MRSA in clinical cultures, mortality and adverse events. The study protocol has been registered with ClinicalTrials.gov (NCT00711854). Results: Overall, 150 patients were randomized to one of the two treatment arms between January 2009 and December 2013 and were included in the ITT analysis. Of these 56/75 (74.7%) in the linezolid group and 59/75 (78.7%) in the trimethoprim/sulfamethoxazole and rifampicin group experienced clinical success (risk difference 4%, 95% CI 29.7% to 17.6%). The results were confirmed by the PP analysis, with 54/66 (81.8%) cured patients in the linezolid group versus 52/59 (88.1%) in the trimethoprim/sulfamethoxazole and rifampicin group (risk difference 6.3%, 95% CI 26.8% to 19.2%). There were no statistically significant differences between the two groups in any of the secondary outcomes, including microbiologically documented failure. Four adverse drug reactions attributed to the study medication occurred in the linezolid group versus nine in the trimethoprim/ sulfamethoxazole and rifampicin group. Conclusions: Compared with linezolid, trimethoprim/sulfamethoxazole and rifampicin seems to be non-inferior in the treatment of MRSA infection.
The Pathophysiology of Chronic Graft Failure in the Cardiac Transplant Patient

Following cardiac transplantation, many patients develop chronic deterioration of graft function, which may lead to a clinical syndrome similar to native chronic heart failure (CHF). This condition of chronic cardiac graft failure (CGF) may also share pathophysiological processes comparable with that of CHF. However, the unique environment following cardiac transplantation may also contribute with a variety of unique mechanisms, deserved of special attention. This review article discusses the complex pathophysiology of CGF after cardiac transplantation, an important yet neglected condition of transplant medicine.
Mango contact allergy.

A previously healthy 25‐year‐old nongovernmental organization volunteer in Malawi developed acute swelling of both lips and a “cold sore” on the inner aspect of the lower lip and some mild patchy erythema to his face and ears. He reported no fever or pain, but did notice some tingling of the lips and general malaise. He denied any new intimate partners, foods, or other exposures. The patient reported no history of …
Use of a remifentanil–propofol mixture for pediatric flexible fiberoptic bronchoscopy sedation

Summary Background: Flexible fiberoptic bronchoscopy is an important diagnostic tool for pediatric pulmonologists. Because of its favorable respiratory profile, ketamine has become a popular sedative for this procedure, but may be associated with unpleasant emergence reactions in the older child. Remifentanil is a newer, ultra-short acting opioid that has been shown to provide effective sedation and cough suppression for fiberoptic bronchoscopy when combined with inter
Phenotypic Diversity of the Lung Vasculature in Experimental Models of Metastases

In vivo phage display is a screening method in which peptides homing to specific vascular beds are selected after IV administration of a random peptide library. This strategy has revealed a vascular address system that allows tissue-specific targeting of normal blood vessels and angiogenesis-related targeting of tumor blood vessels by selected peptides. Many vascular receptors or "addresses" targeted by homing peptides have been identified. One such vascular receptor of normal lung endothelium is membrane dipeptidase (MDP), which was found by in vivo phage display to bind the tripeptide motif gly-phe-glu (GFE). Our studies with GFE peptide and lung vasculature suggest that MDP mediates cancer cell adhesion to lung vasculature and the development of lung metastases, but that MDP is not present in the vasculature of lung metastases. MDP appears to occupy a vascular distribution that is similar to the pulmonary artery circulation. These results demonstrate the promise of defining critical functional and anatomic characteristics of endothelial cells in lung and other organs by in vivo phage display.
GENETIC AND DEVELOPMENTAL ANALYSIS OF ABDOMINAL PIGMENTATION DIFFERENCES ACROSS SPECIES IN THE DROSOPHILA DUNNI SUBGROUP

Abdominal pigmentation pattern varies dramatically among the species of the Drosophila dunni subgroup across the islands of the Caribbean. Previously, we developed a quantitative measure of abdominal pigmentation to assess phenotypic variation within and between species of this group. In this paper, we use this quantitative measure in an interspecific genetic analysis to decipher the underlying genetic basis of pigmentation differences between one of the lightest and the darkest species in the group. Our analysis shows that pigmentation expression in different areas of the abdomen is under separate genetic control. For these different abdominal regions, we detected a wide range of genetic effects, including X-linked, autosomal additive, near single-gene dominant, and sex-specific effects. Combining these genetic results with our earlier phenotypic and phylogenetic analyses, we present a simple conceptual model to explain how change in the control of expression of pigmentation has evolved throughout the D. dunni subgroup.
Distortion optimized multiple channel image transmission under delay constraints

When multiple channels are aggregated into a higher bandwidth logical channel, strategic product codes can be used to protect data against both channel losses and failures. Previous work in (W. Xu et al., Proc. ICME, vol.1, p.285-288, 2003) has considered a delay-optimal partitioning scheme given pre-determined error correction codes (ECCs). In order to achieve an improved distortion performance, image bit streams can be partitioned together with an appropriate selection of ECCs based on channel conditions. This paper addresses the problem of jointly partitioning image data over multiple channels and selecting product coding rates from a finite set to minimize the decoding distortion under delay constraints. Experimental results show that the image quality degrades very slightly when the delay constraint decreases over a wide range, with a gain up to 4.5 dB achieved over that using a sequential optimization method.
The Relationship Between Bedform and Log Orientation in a Paleogene Fluvial Channel, Weißelster Basin, Germany: Implications for the Use of Coarse Woody Debris for Paleocurrent Analysis

Abstract Isolated logs preserved in the Alterer Flussande of the Weiselster basin, Germany, are examined relative to their subjacent bedform. Paleocurrent analyses conducted on both the log orientation and its underlying bedform are used to determine whether or not any relationship exists between these two structures. Two patterns emerge from this investigation. When the data set is taken collectively, the mean vector of the log orientation is in a subperpendicular relationship to the mean vector of their bedforms. This coarse woody detritus is not oriented preferentially parallel to paleocurrent direction as has been previously hypothesized. In addition, when individual log orientations are compared with their underlying bedforms, logs may be oriented parallel, subperpendicular, or perpendicular to the bedform. There is no statistical preference for any particular orientation in the data set. Comparison is made with an actualistic data set from the Lassa Distributary of the Rajang River delta where a sim...
Placental Cadmium Levels Are Associated with Increased Preeclampsia Risk

Environmental exposure to heavy metals is a potentially modifiable risk factor for preeclampsia (PE). Toxicologically, there are known interactions between the toxic metal cadmium (Cd) and essential metals such as selenium (Se) and zinc (Zn), as these metals can protect against the toxicity of Cd. As they relate to preeclampsia, the interaction between Cd and these essential metals is unknown. The aims of the present study were to measure placental levels of Cd, Se, and Zn in a cohort of 172 pregnant women from across the southeast US and to examine associations of metals levels with the odds of PE in a nested case-control design. Logistic regressions were performed to assess odds ratios (OR) for PE with exposure to Cd controlling for confounders, as well as interactive models with Se or Zn. The mean placental Cd level was 3.6 ng/g, ranging from 0.52 to 14.5 ng/g. There was an increased odds ratio for PE in relationship to placental levels of Cd (OR = 1.5; 95% CI: 1.1–2.2). The Cd-associated OR for PE increased when analyzed in relationship to lower placental Se levels (OR = 2.0; 95% CI: 1.1–3.5) and decreased with higher placental Se levels (OR = 0.98; 95% CI: 0.5–1.9). Similarly, under conditions of lower placental Zn, the Cd-associated OR for PE was elevated (OR = 1.8; 95% CI: 0.8–3.9), whereas with higher placental Zn it was reduced (OR = 1.3; 95% CI: 0.8–2.0). Data from this pilot study suggest that essential metals may play an important role in reducing the odds of Cd-associated preeclampsia and that replication in a larger cohort is warranted.
Inclusive Education Complexly Defined for Teacher Preparation: The Significance and Uses of "Error".

ABSTRACTResearch in the implementation of inclusive education in international contexts shows that progress in the Global South appears to lag behind nations in the North. In this paper, I investigate this phenomenon not by associating it with regional cultural and socioeconomic resource limitations, but by reconsidering the assumptions within inclusive education scholarship itself. Drawing on the theory of disability as complex embodiment [Siebers, T. (2008). Disability Theory. Ann Arbor: University of Michigan Press], I examine the sufficiency of the social model of disability as a foundational basis for teacher preparation for inclusive education in any sociocultural context. I argue for a post-positivist realist theorising of teacher preparation for inclusive education that, through an understanding of error, can imbricate the diversity of historically specific material contexts around the world. To illustrate the affordances of this theory, I examine two dilemmas in a Southern and Northern context, r...
Defect Chalcopyrite Cu(In1-x, Gax)3Se5 Polycrystalline Thin-Film Materials

The defect chalcopyrite material CuIn3Se5 has been identified as playing an essential role in efficient photovoltaic action in CuInSe2-based devices; it has been reported to be of n-type conductivity, forming a p-n junction with its p-type counterpart CuInSe2. Because the most efficient cells consist of the Cu(In1-xGax)Se2 quaternary, knowledge of some physical properties of the Ga-containing defect chalcopyrite Cu(In1-xGax)3Se5 may help us better understand the junction phenomena in such devices. Polycrystalline Cu(In1-xGax)3Se5 (with 0<x<l) thin films have been grown on 7059 Corning glass, soda-lime silica glass, n-type (100)Si, and Mo-coated soda-lime glass by coevaporation from elemental sources. In general, optical data show direct optical bandgaps that range from 1.20 eV for x=0 to ~1.85 eV for x=l (this represents ~200 meV higher bandgaps than the Cu(In,Ga)Se2 counterparts). Micrographs of the thin films show a substantial change in morphology as the Ga content is increased—for identical conditions of growth rate and substrate temperature. X-ray diffraction patterns agree with previously publish data for the ternary case (x=0), where these materials have been referred to as ordered vacancy compounds. Pole figures confirm a high degree of texturing in the films and a change in preferred orientation as Ga content is increased.
ECG phasic voltage changes associated with spontaneous pneumothorax in a patient with vanishing lung syndrome

Alternating or phasic ECG voltage changes are most commonly associated with intrinsic myocardial electrophysiological perturbations or mechanical oscillation within a pericardial effusion. Rare descriptions of electrical alternation have been reported with pneumothorax. We present a case of a 53-year-old woman with vanishing lung syndrome who presented with spontaneous left pneumothorax and phasic ECG voltage changes that resolved after re-expansion of the lung.
A medium free of agar, serum and peptone for plaque assay of herpes simplex virus.

SummaryMethods have been described for quantitative plaque assay of herpes simplex virus either in bottle culture or in Leighton tubes. The overlay employed was devoid of agar, peptones and serum, which are viewed as undesirable constituents. Use of agar overlay results in production of plaques from only a small fraction of the potential plaque-forming population. The inhibition of plaque formation by agar can be reversed by addition of protamine sulfate at a level of approximately 800 μg/ml. Possible uncertainties associated with the use of mixtures of agar and protamine can be avoided by substitution of methyl cellulose with which a further 10-fold increase in sensitivity of the assay was obtained.
Hope and health related quality of life of older women who have had heart attacks

HOPE AND HEALTH RELATED QUALITY OF LIFE OF OLDER WOMEN WHO HAVE HAD HEART ATTACKS by Alice Mary Kelly-Tobin Advisor: Dr Martha Whetsell Background: Heart disease is the number one cause of death and leading cause of disability in adults in the United States. Coronary heart disease (CHD) is the most common form of heart disease with heart attack as its acute manifestation. Health Related Quality of Life (HRQoL) is a multidimensional concept of self-perception of physical, emotional health, and overall sense of well-being. Hope, an inner process focusing on maintaining physical and mental well-being, is considered necessary for survival of chronic illnesses, such as CHD. Method: Women age 65 and older who have had heart attacks (N=91) volunteered to participate in this quantitative non-experimental correlational study. They completed a demographic questionnaire, SF12 and HHI. Findings: Marital status was related to HHI scores, t(90) = -2.70, p = .041, with married participants having greater mean score (40.87) compared to singles (38.39). General Health, r(89) = .244, p = .02; Mental Health, r(89) = .352, p = .001; Vitality, r(89) = .221, p = .035; Social Functioning, r(89) = .333, p = .001 and Role Emotion , r(89) = .223, p = .034 correlated with HHI. Marital Status , t(89) = 2.07, p = .041 and Mental Health, t(88) = 3.40, p = .001, best predicted the HHI and explained an adjusted total of 13.8% of variance in HHI scores, R = .397, F(1,88) = 8.21, p = .001. Relationship between HRQoL and HHI revealed significant findings pertaining to age and ethnicity. Cronbach's alpha on HHI (α=.838) and SF 12 (α=.822) revealed HOPE AND HRQoL OF OLDER WOMEN v internal consistency.
Noninvasive inhaled nitric oxide for persistent pulmonary hypertension of the newborn: A single center experience.

INTRODUCTION Nitric oxide is a potent, selective pulmonary vasodilator that has been proven to decrease pulmonary vascular resistance and has been part of the treatment arsenal for persistent pulmonary hypertension of the newborn (PPHN). In 2009, the approach to the administration of inhaled nitric oxide (iNO) at Winnie Palmer Hospital for Women and Babies (WPH) changed to emphasize avoiding invasive ventilation while maintaining optimal ventilation to perfusion ratio, avoiding hyperventilation and alkalosis agents, and avoiding hyperoxemia and hyperoxia exposure. Our aim is to describe the outcomes of babies whose primary treatment for PPHN was noninvasive (NIV) iNO. METHODS A retrospective chart review of neonates born at WPH from October 1, 2009 through October 1, 2014. INCLUSION CRITERIA >34 weeks' gestation, echocardiographic evidence of PPHN within the first week of life, and NIV iNO as the primary treatment. RESULTS Twenty-four babies met criteria: 21 solely treated noninvasively, 3 required invasive support. Supplemental oxygen need was ≥50% for 21 babies pre-iNO treatment and dropped to <30% for all babies post-iNO. Average exposure to supplemental oxygen was 6.3 days. Mean duration of iNO administration was 2.5 days. Average length of stay was 14 days. All babies survived. CONCLUSION Our review revealed a low incidence of escalation to invasive ventilation. Non-invasive iNO was found to be an effective and well-tolerated frontline approach for treating PPHN in near-term and term infants with an intact respiratory drive. Further studies could provide the necessary evidence on clinical outcomes as well as cost effectiveness to guide best practice.
Herpesvirus in the Induction of Cervical Carcinoma

From its beginnings in epidemiology, the hunt for a virus as the possible cause of cervical cancer has led to the identification of a second type of herpesvirus and the detection of significantly high antibody titers to this virus in patients with invasive carcinoma of the cervix. Describing the accumulating circumstantial evidence, the authors outline a variety of approaches that may soon clinch the proof.
Correlation between helium atmospheric pressure plasma jet (APPJ) variables and plasma induced DNA damage

A helium atmospheric pressure plasma jet (APPJ) source with a dielectric capillary and two tubular electrodes was used to induce damage in aqueous plasmid DNA. The fraction of different types of DNA damage (i.e., intact or undamaged, double strand breaks (DSBs), and single strand breaks (SSBs)) that occurred as the result of plasma irradiation was quantified through analysis of agarose gel electrophoresis images. The total DNA damage increased with an increase in both flow rate and duration of irradiation, but decreased with an increase in distance between the APPJ and sample. The average power of the plasma was calculated and the length of APPJ was measured for various flow rates and voltages applied. The possible effects of plasma power and reactive species on DNA damage are discussed.
Online graduate educational technology program: An illuminative evaluation

Abstract With continued growth in online courses and programs in higher education a pressing need exists to evaluate their perceived quality and effectiveness. Evaluation criteria – course evaluations, student surveys and retention data – from previous online program evaluations were used in this study. An illuminative evaluation using descriptive and scientific analysis was undertaken for a graduate degree program in educational technology. Course and program-level data were analyzed to compare quality for two programs – an existing hybrid and new online. Analysis of student enrollments, course evaluations, survey results, retention, and time to completion reveal similar experiences reported from students in both programs. Results suggest that a majority of students were satisfied with their graduate experience and view those experiences as worthwhile. This illuminative evaluation provides evidence that online graduate programs are comparable and can satisfy stakeholders’ expectations while maintaining high levels of quality.
Hypertension during Weight Lifting Reduces Flow-Mediated Dilation in Nonathletes

Purpose: The purpose of this study was to determine whether increased intraluminal pressure is the damaging factor that reduces flow-mediated dilation (FMD) in young, healthy subjects after resistance exercise to maximal exertion. Hypothesis: Attenuating the rise in brachial artery pressure during weight lifting by placing a blood pressure cuff on the upper arm prevents postexercise impairment of brachial artery FMD in sedentary individuals. Methods: Nine sedentary individuals who exercise once a week or less and six exercise-trained individuals who exercise three times a week or more performed leg press exercise to maximal exertion on two separate occasions. During one visit, a blood pressure cuff, proximal to the site of brachial artery measurement, was inflated to 100 mm Hg to protect the distal vasculature from the rise in intraluminal pressure, which occurs during resistance exercise. Brachial artery FMD was determined using ultrasonography before and 30 min after weight lifting. Results: Without the protective cuff, brachial artery FMD in sedentary individuals was reduced after weight lifting (9.0% ± 1.2% prelift vs 6.6% ± 0.8% postlift; P = 0.005), whereas in exercise-trained individuals, FMD was unchanged (7.4% ± 0.7% prelift vs 8.0% ± 0.9% postlift; P = 0.543). With the protective cuff, FMD no longer decreased but rather increased in sedentary individuals (8.7% ± 1.2% prelift vs 10.5% ± 1.0% postlift, P = 0.025). An increase in FMD was also seen in exercise-trained subjects when the cuff was present (6.6% ± 0.7% prelift vs 10.9% ± 1.5% postlift, P < 0.001). Conclusion: Protecting the brachial artery from exercise-induced hypertension enhances FMD in sedentary and exercise-trained individuals. These results indicate that increased intraluminal pressure in the artery contributes to the reduced FMD after heavy resistance exercise in sedentary individuals.
Detection of Abnormal Milk with Impedance Microbiology Instrumentation

Mastitic milk was detected by obtaining conductance measurements using an impedance microbiology Bactomatic 120 SC instrument. Conductance readings separated normal and abnormal milks after 30 min at 25°C when readings differed by more than 2 to 3% and exceeded the variance among instrument module wells. Samples blended from four quarters of a cow indicated milk from one quarter was abnormal if the salt level in the abnormal quarter raised the blend conductivity above that of normal samples and variance among the wells. Either solid or liquid substrates that contained stimulants could be used to accelerate bacterial acid production or reduce impedance detection times and did not affect the ability to detect abnormal milk. However, measurements varied with the volume of sample in the well, suggesting that fixed 1-ml liquid volumes of milk be used. Such volumes would allow detection of abnormal milk and bacterial load on the same sample.
The Public’s Stance on Prisoner Reentry: Policy Support and Personal Acceptance

Prior research has established the public recognizes the obstacles former prisoners’ face upon release from prison, and they support various offender reentry services. Still, we do not have a solid understanding of what affects public opinion on prisoner reentry nor is it clear that support for policies also extends to individuals’ willingness to engage with ex-offenders on a personal level. Drawing on a random sample of South Carolina residents, the current study examines the extent to which citizens’ belief in offenders’ redeemability influences their support for reentry initiatives at a policy and personal level. The results of this study show support for several types of reentry services, reveal that policy-level opinions and personal-level acceptance depend on the type of services, and demonstrate that belief in the redeemability of offenders is an important predictor of the degree to which the public embraces reentry programming.
The Silicon Valley Ethos: Tech Industry Products, Discourses, and Practices:

This special issue of Television and New Media critically examines the ethos of Silicon Valley, imagined broadly, by analyzing its products, discourses, and practices. We argue that, as a technolog...
Neoliberal Discourses: Toward a Deeper Understanding of a Global Latino Education

This article explores the dynamic discursive interactions between two keenly related concepts, globalization and neoliberalism. Though largely synonymous in the social imaginary, in fact, these ideas are different and analytically distinct. They need unpacking. The notion that both globalization and neoliberalism are empirically verified social realities must be advanced. What’s more as they affect the global-local social relation, varying manifestations such as gentrification, the global emergence of schools of choice (charter schools), and the economic and geographic dislocations of subordinate populations become evident. Relying on empirical studies and everyday lived cultural experience in the rebuilding of the city of New Orleans post-Hurricane Katrina, I finally examine the implications for a Global Latino education and pedagogy.
Association Between Sinus Membrane Thickness and Membrane Perforation in Lateral Window Sinus Augmentation: A Retrospective Study

Background: Association between Schneiderian membrane thickness and membrane perforation is examined in lateral window sinus augmentation.Methods: This retrospective study reviewed records of 551 patients who underwent lateral sinus augmentation at Tufts University School of Dental Medicine, Boston, Massachusetts, from June 1, 2006 to May 31, 2015. Preoperative cone-beam computed tomography images were analyzed to evaluate possible association among membrane thickness, residual bone height, and membrane perforation. Data were evaluated using Mann–Whitney U test at P <0.05.Results: Total 167 patients (95 males and 72 females) met the eligibility criteria and were included in the study. Among them, 47 patients had Schneiderian membrane perforation (perforation group). Mean membrane thickness was 0.84 ± 0.67 mm in the perforation group and 2.65 ± 4.02 mm in the non-perforation group. There was a statistically significant difference in membrane thickness between groups (P <0.001). Mean residual ridge thicknes...
Flip chip joining with low temperature solders and thermal gradient bonding

In this study, we investigated effects of thermal gradient of joint during flip chip bonding on intermetallic compound (IMC) growth for several solder materials. Cu/Sn-2.5Ag/Cu joint was prepared by bonding electroplated Cu/Sn-2.5Ag bump on Cu pad. Ni/Sn/Ni, Ni/In/Ni, Ni/In-48Sn/Ni, and Ni/Sn-58Bi/Ni joints were prepared by solder capping by IMS on electro-less plated Ni/Au post and bonding it on electro-less plated Ni/Au pad. Joint pitch and diameter were 80 micron and 38 micron respectively. Joints prepared by thermal gradient bonding (TGB) were compared with those by homogeneous temperature bonding (HTB). With Cu/Sn-2.5Ag/Cu joints, firstly we confirmed faster growth of IMCs at a cold end than a hot end of the joint and thicker IMC in the TGB joint than in the HTB joint. These important features of TGB were also confirmed experimentally on joints with low temperature solder materials. It indicates that TGB can be used for the joints with low temperature solders to shorten bonding time for full IMC joint. IMC growth at the cold end of Ni/In/Ni joint prepared by TGB was as fast as that of Ni/Sn/Ni joint by HTB.
Modeling Battery Performance Due to Intercalation Driven Volume Change in Porous Electrodes

Author(s): Garrick, TR; Higa, K; Wu, SL; Dai, Y; Huang, X; Srinivasan, V; Weidner, JW | Abstract: Simulations are presented that result from incorporating dimensional and porosity changes in porous electrodes caused by volume changes in the active material during intercalation into a detailed lithium-ion battery model. Porosity and dimensional changes in an electrode can significantly affect the resistance of the battery during cycling, which in turn alters the reaction distributions in the porous electrodes. In addition, volume changes generate stresses in the electrode which can lead to premature failure of the battery. Here, material conservation equations are coupled with the mechanical properties of porous electrodes to link dimensional and porosity changes to stresses and the resulting resistances that occur during the intercalation processes. Through the use of porous rock mechanics, porosity and strain gradients can be predicted based on state of discharge and discharge rate. Several different battery casings and discharge rates are examined and operating curves are predicted.
Abstract 472: PPARγ-agonist Rosiglitazone Modulates Macrophage Proliferation, Polarization, and Inflammatory Function

Background: Macrophages are central to the initiation, progression, and repair of inflammation. Rosiglitazone (Rosi), an antidiabetic thiazolidinedione (TZD), is a PPAR-γ agonist. Although TZDs improve certain cardiovascular risk factors and surrogate endpoints, they do not appear to reduce major cardiovascular events, and cardiovascular risk of Rosi has been a particular concern. Previously undetected effects on macrophages could provide a more nuanced understanding of how Rosi and other TZDs impact inflammation. Results: To this end, we have characterized the effects of Rosi on bone marrow-derived macrophages (BMMs) in vitro . M2-polarized BMMs express canonical mRNA markers, IL10 and Ym1. In this system, compared to polarized untreated cells and M2s treated with 1μM of the TZD Pioglitazone (Pio), M2s treated with 1μM Rosi express lower levels of anti-inflammatory M2 markers (IL10: 0.07 ± 0.01 for Rosi vs. 0.73 ± 0.04 for untreated vs. 1.00 ± 0.06 a.u. for Pio; Ym1: 0.06 ± 0.00 for Rosi vs. 0.81 ± 0.06 for untreated vs. 1 ± 0.04 a.u. for Pio). M2s polarized in the presence of Rosi express diminished protein levels of the M2 marker CD206 when compared to untreated M2s (Rosi 0.44 vs. untreated 1.00 a.u.). Culture of marrow with BMM-differentiating media in the presence of Rosi increased proliferation compared to untreated marrow and to marrow treated with Pio or the PPARγ antagonist GW9662, as measured by cell counts (Rosi 189 ± 19% relative to untreated BMM counts; Pio 115 ± 4%; GW9662 103 ± 4%; n=4, p -3 ). In an in vitro system of efferocytosis, macrophages differentiated in the presence of Rosi show impaired uptake of apoptotic foam cells in comparison to untreated BMMs (Rosi 0.77 vs. untreated 1.00 a.u.). Conclusion: Overall, we find that rosiglitazone, more than pioglitazone, increases macrophage proliferation and reduces anti-inflammatory markers and effector functions. Future work will seek to delineate the mechanism of this apparent inflammatory effect on macrophages.
Psychiatric Illness and Sleep in Older Adults: Comorbidity and Opportunities for Intervention

This article reviews the literature examining the association between sleep disorders and psychopathology among older adults. Similar to the younger adult literature, the authors found that sleep disorders are robustly associated with anxiety, depression, dementia, and suicidal behavior in late life. Clinical implications and opportunities for intervention are discussed.
Terror as Usual: The Role of the Model Minority Myth in Asian American Women’s Suicidality

This article examines the influence of the model minority myth on the formation of suicidal tendencies among Asian American women. These women experience fractured realities under the myth as a for...
Radiology of Pediatric Laryngeal Pathology

Knowledge of the embryology of the larynx and the trachea allows for a better understanding of common congenital anomalies and disease processes involving the pediatric airway.
Effects of Aging on Sleep in the Golden Hamster

The golden hamster (Mesocricetus auratus) has been a model organism for the study of circadian rhythmicity and, in particular, the effects of age on the circadian system. Surprisingly, nothing is known about the effects of advanced age on sleep in this species. As a first step in determining the effects of aging on sleep in the golden hamster, we recorded sleep for 24 hours in 12 young (3 months) and 18 old (17-18 months) golden hamsters entrained to a 14:10 light:dark (LD) cycle. Aged hamsters exhibited small but significant increases in overall NREM sleep time, primarily due to an increase in time the old animals spent in the NREM sleep state during the dark period relative to the young hamsters. There were no significant differences in REM sleep, median sleep episode length, or the number of arousals. The most striking differences between the sleep of young and old hamsters was in NREM delta (0.5-4 Hz) power per epoch. Old hamsters showed approximately 27% less (p=0.0004) delta power per NREM epoch than young hamsters. It is possible that increased NREM sleep time in the old hamsters may be a failed attempt to maintain cumulative delta power; ie, old hamsters may have more NREM sleep in order to make up for the lower intensity of their sleep. This decline in delta power with age parallels earlier findings in cats and humans, although has it not been previously reported in rodents.
The History of the Xα Method

The Xα method for handling the quantum theory of atoms, molecules, and solids, has origins which go back 50 years, to the earliest days of wave mechanics. Most of the fundamental ideas were well formed by the 1930’s. After the delay of World War II, and after the development of electronic digital computers during the 1950’s, the method has been of practical value since the 1960’s. Various recent developments, including the multiple scattering Xα method, and the concept of the transition state, have been available only during the past several years, and they have led to a rapid rate of expansion in the use of the method, which is adaptable to a great variety of problems in the structure of matter.