cssi/SciSciGPT-SciSciNet huggingface dataset:
An Islamic Bioraphical Dictionary of the Eastern Kazakh Steppe, 1770–1912 . By Qurbân-'Alî Khâlidî. Edited by Allen J. Frank and Mirkasyim A. Usmanov. Brill'i Inner Asian Library, no. 12. Leiden and Boston: Brill, 2004. xxvi, 179 pp. $107.00 (cloth).

An Islamic Biographical Dictionary of the Eastern Kazakh Steppe, 1770–1912. By Qurbân-'Ali Khâlidi. Edited by Allen J. Frank and Mirkasyim A. Usmanov. Brill'i Inner Asian Library, no. 12. Leiden and Boston : Brill, 2004.
Temperature dependent aqueos solubility of actinomycin D.

L'actinomycine D est solubilisee dans un milieu aqueux par une technique de congelation suivie de degel, ce qui permet d'atteindre des concentrations de 1 mg/ml a 4°C et de 0.5 mg/ml a la temperature du laboratoire. Pour obtenir une absorption rapide de l'actinomycine D les concentrations ne doivent pas depasser 0.25 mg/ml.
Age-grouped differences in bipolar mania

Abstract Objective This review of published studies compares scores on individual items of mania rating scales that systematically recorded symptom severity in persons diagnosed with bipolar disorder to identify age-grouped differences. Methods An extensive literature search identified item scores from mania rating scales, with a particular emphasis on baseline Young Mania Rating Scale (YMRS) item scores in published double-blind, placebo-controlled studies of bipolar I manic disorder. These baseline YMRS item scores were assessed as a proportion of the total YMRS score and compared by age group. Additional YMRS item/total scores in subjects with bipolar spectrum disorders were added to expand the analysis. Results Preadolescents with bipolar disorder had significantly higher YMRS item scores than adolescents on aggression, irritability, and motor activity. Young Mania Rating Scale baseline item scores relative to the YMRS total score revealed that adolescents diagnosed with bipolar I mania scored comparatively higher than did adults on YMRS aggression and irritability items, whereas adults with bipolar I manic disorder scored comparatively higher on the grandiosity and sexual interest items. Age-grouped findings from subjects diagnosed with bipolar I, II, and Not Otherwise Specified (NOS) disorders yielded similar age-grouped results. Conclusion In age-grouped YMRS item assessments of bipolar mania, anger dyscontrol was most prominent for youth, whereas disordered thought content was paramount for adults.
Intuition and Nature in Kant and Goethe

: This essay addresses three specific moments in the history of the role played by intuition in Kant's system. Part one develops Kant's attitude toward intuition in order to understand how ‘sensible intuition’ becomes the first step in his development of transcendental idealism and how this in turn requires him to reject the possibility of an ‘intellectual intuition’ for human cognition. Part two considers the role of Jacobi when it came to interpreting both Kant's epistemic achievement and what were taken to be the outstanding problems of freedom's relation to nature; problems interpreted to be resolvable only via an appeal to ‘intellectual intuition’. Part three begins with Kant's subsequent return to the question of freedom and nature in his Critique of Judgment. With Goethe's contemporaneous Metamorphoses of Plants as a contrast case, it becomes clear that whereas Goethe can embrace the role of an intuitive understanding in his account of nature and within the logic of polarity in particular, Kant could never allow an intuition of nature that in his system would spell the very impossibility of freedom itself.
Hard X-Ray Tests of the Unified Model for an Ultraviolet-detected Sample of Seyfert 2 Galaxies

An ultraviolet-detected sample of Seyfert 2 galaxies shows heavy photoelectric absorption in the hard X-ray band. The presence of UV emission combined with hard X-ray absorption argues strongly for a special geometry which must have the general properties of the Antonucci and Miller unified model. The observations of this sample are consistent with the picture in which the hard X-ray photons are viewed directly through the obscuring matter (molecular torus?) and the optical, UV, and soft X-ray continuum are seen in scattered light. The large range in X-ray column densities implies that there must be a large variation in intrinsic thicknesses of molecular tori, an assumption not found in the simplest of unified models. Furthermore, constraints based on the cosmic X-ray background suggest that some of the underlying assumptions of the unified model are wrong.
Depression in Parkinson's disease

Depression occurs in 40% to 50% of Parkinson's disease (PD) patients. From research over the last decade, this co-occurrence appears to be more than an emotional reaction to disability. Replacement of the neurotransmitter, dopamine, benefits the PD motor functions, and the neurotransmitter, serotonin, in antidepressants, reduces depressive symptoms. However, identification of the physiological linkage between PD and depression continues to evade research efforts.
Mixed hp-finite element method for linear elasticity with weakly imposed symmetry

Abstract The paper presents a generalization of Arnold–Falk–Winther elements to meshes with elements of variable order. The formulation is straightforward but the stability analysis involves a non-trivial modification of interpolation operators. The analysis addresses only h -convergence but the presented numerical results indicate p -convergence as well.
Peirce and the logical status of diagrams

In this paper, I aim to identify Peirce’s great contribution to logical diagrams and its limit.Peirce is the first person who believed that the same logical status can be given to diagrams as to symbolic systems.Even though this belief led him to invent his own graphical system, Existential Graphs, the success or failure of this system does not determine the value of Peirce’s general insights about logical diagrams.In order to make this point clear, I will show that Peirce’s revolutionary ideas about diagrams not only overcame some important defects of Venn diagrams but opened a new horizon for logical diagrams.Finally, I will point out where Peirce’s new horizon for logical diagrams stopped and will claim that this limit is mainly responsible for the discrepancy between Peirce’s and others’ estimates of his contribution to logical diagrams
Convolution of fabric data to determine probability distribution

Abstract To investigate the higher order, multimodal characteristics of fabric data populations, five filter operators are constructed on the surface of the reference hemisphere for convolution with fabric data. These operators include spherical unit disk, triangle, sinc, sinc2 and Gaussian functions. To illustrate filter performance, two fabric data sets, taken from the lower Schoonover sequence of the Northern Independence Mountains, Nevada, are convolved with the filters. The results show that the spherical unit disk, triangle and sinc operators are especially useful for identifying characteristics of the population density distribution and related probability contours for unimodal data sets. The Gaussian and sinc2 operators, however, provide increased resolution of the higher frequency components for multimodal fabric data sets, along with relative statistical probability contours from which inferences on the probability distribution of the population can be made. In general, the convolution process is a very effective tool for analyzing the multimodal behaviour of fabric data, because of the ease and the flexibility with which filter operators may be designed.
Rapid cold-hardening increases membrane fluidity and cold tolerance of insect cells.

Abstract The rapid cold-hardening (RCH) response not only confers dramatic protection against cold-shock (non-freezing) injury, but also “instantaneously” enhances organismal performance. Since cold-shock injury is associated with damage to the cell membrane, we investigated the relationship between RCH and changes in cold tolerance and membrane fluidity at the cellular level. None of the adult flies (Sarcophaga bullata) in the cold-shocked treatment group survived direct transfer to −8 °C for 2 h; in contrast, 64.5% of flies in the RCH group survived exposure to −8 °C. Differences between the treatment groups also were reflected at the cellular level; only 21.3% of fat body cells in the cold-shocked group survived compared to 68.5% in the RCH group. Using 31P solid-state NMR spectroscopy, we determined that membrane fluidity increased concurrently with rapid cold-hardening of fat body cells. This result suggests that membrane characteristics may be modified very rapidly to protect cells against cold-shock injury.
Expression of β-amyloid precursor protein in reactive astrocytes following neuronal damage

Abstract Although the β-amyloid peptide is an established core component of neuritic plaques that accumulate in Alzheimer's disease, the mechanisms responsible for its deposition are not well understood. We now report that lesions of rat hippocampal neurons cause a time-dependent, long-lasting elevation of immunoreactivity for the β-amyloid precursor protein (APP) in neighboring astrocytes, a cell type not normally containing the protein. The increase represents astroglial expression of the protein rather than a scavenging of APP released by damaged neurons. Immunoelectron microscopy confirmed that APP-containing cells are reactive astroglia, both surrounding capillaries and within the neuropil. These results demonstrate that neuronal damage stimulates APP expression in adult brain and suggest that reactive astrocytes may be a source of the β-amyloid that forms neuropathological plaques in Alzheimer's disease.
Gadamer's Hermeneutic Externalism

L'A. defend la these selon laquelle Gadamer adopte la conception realiste de la verite correspondance en ce ce sens qu'il developpe une epistemologie externaliste qui echappe a l'objection epistemique de type internaliste definie par D. Ingram, J. Grondin et K.O. Apel dans le cadre de la philosophie continentale. Examinant les notions de connaissance, entendement et verite ontologique, l'A. definit la position de Gadamer comme une externalisme hermeneutique non-naturaliste qui s'inscrit dans la tradition de la philosophie transcendantale jusqu'a Husserl et Heidegger
The Neighborhood Context of Well-Being

Health-related problems are strongly associated with the social characteristics of communities and neighborhoods. We need to treat community contexts as important units of analysis in their own right, which in turn calls for new measurement strategies as well as theoretical frameworks that do not simply treat the neighborhood as a "trait" of the individual. Recent findings from the Project on Human Development in Chicago Neighborhoods support this thesis. Two major themes merit special attention: (1) the importance of collective efficacy for understanding health disparities in the modern city; and (2) the salience of spatial dynamics that go beyond the confines of local neighborhoods. Further efforts to explain the causes of variation in collective processes associated with healthy communities may provide innovative opportunities for preventive intervention.
New insights into parental effects and toxicity: Mate availability and diet in the parental environment affect offspring responses to contaminants

Parental effects manifest as alterations in offspring phenotype resulting from the parental phenotype and/or parental environment. We evaluated the effects of parental diet quality and mating strategy on the toxicant tolerance of offspring in Biomphalaria glabrata snails. We raised snails either individually (self-fertilizing) or in groups of three (outcrossing) on a diet of uncooked lettuce, fish food, cooked lettuce, or cooked lettuce plus fish food. We then exposed their offspring to cadmium and malathion challenges. Cadmium tolerance varied with parental diet and was greater in the offspring of outcrossing snails than self-fertilizing snails. Malathion tolerance was not affected by parental diet but was greater in the offspring of outcrossing snails. These results indicate that offspring responses to stressors are heavily influenced by parental experience, but may depend on the specific stressor and the mechanism of action and/or detoxification.
Implicit sequence learning without motor sequencing in young and old adults

The ability to detect patterns and organize individual events into complex sequences is a fundamental cognitive skill that is often learned implicitly. The serial response time (SRT) task has been widely used to investigate implicit sequence learning, but it remains unclear whether people learn a perceptual or motor sequence in this task. This study reports three experiments that build on previous research by Goschke and colleagues using an auditory SRT task in which the stimulus-to-response mapping changes on every trial to eliminate spatio-motor sequencing. The current study extends earlier work in three ways. First, healthy young and older adults were tested rather than the neuropsychological patients used in previous research. Second, sequences of different structural complexity were investigated including first- and second-order repeating sequences as well as higher-order probabilistic sequences. Third, the potential role of explicit knowledge was examined using three separate tests of declarative knowledge. Results indicate that young and old adults are able to learn purely perceptual auditory sequences, but that explicit knowledge contributes to learning of repeating sequences by young adults.
Design And Test of the 80386

A complex design effort, the 80386 was nevertheless one of the company's most successful projects. The work was completed in less time than scheduled and set an Intel record for tapeout to mask fabricator. The strategy incorporated both top-down and bottom-up design approaches. The top-down flow was external architectural definition, internal architecture, internal unit RTL (register transfer logic) and finally detailed logic. The bottom-up flow was detailed transistor and cell circuit design and layout, block (ALU, PLA, etc.) circuit design and layout, and finally global circuit design and layout. Testability also played an important part in the design's success. The 80386 combines two forms of designed-in test functions: built-in self-test and test hooks or functions explicitly designed in to aid testing.
Mate choice based on a key ecological performance trait

Mate preference for well-adapted individuals may strengthen divergent selection and thereby facilitate adaptive divergence. We performed mate choice experiments in which we manipulated male red crossbill (Loxia curvirostra complex) feeding rates. Using association time as a proxy for preference, we found that females preferred faster foragers, which reinforces natural selection because poorly adapted males would be less likely to obtain a mate as well as less likely to survive. Although theoretical models predict direct preference for adaptation and performance, to the best of our knowledge this experiment provides the first evidence of individuals directly assessing feeding performance in mate choice. In species where assessing the ecological adaptation of potential mates is possible, females may gain fitness benefits from choosing a well-adapted mate directly or indirectly, promoting the use of information about ecological adaptation in mate choice.
A Postweaning Iron-Adequate Diet Following Neonatal Iron Deficiency Affects Iron Homeostasis and Growth in Young Rats

Iron deficiency is among the most prevalent of nutrient-related diseases worldwide, but the long-term consequences of maternal and neonatal iron deficiency on offspring are not well characterized. We investigated the effects of a postweaning iron-adequate diet following neonatal iron deficiency on the expression of genes involved in iron acquisition and homeostasis. Pregnant rats were fed an iron-adequate diet (0.08 g iron/kg diet) until gestational d 15, at which time they were divided into 2 groups: 1) a control group fed an iron-adequate diet, and 2) an iron-deficient group fed an iron-deficient diet (0.005 g iron/kg diet) through postnatal d (P) 23 (weaning). After weaning, pups from both dietary treatment groups were fed an iron-adequate diet until adulthood (P75). Rat pups that were iron deficient during the neonatal period (IDIA) had reduced weight gain and hemoglobin concentrations and decreased levels of serum, liver, and spleen iron on P75 compared with rats that were iron sufficient throughout early life (IA). IDIA rats developed erythrocytosis during postweaning development. Further, hepatic expression of hepcidin in IDIA rats was 1.4-fold greater than in IA rats, which paralleled an upregulation of IL-1 expression in the serum. Our data suggest that an iron-adequate diet following neonatal iron deficiency induced an inflammatory milieu that affected iron homeostasis and early growth and development.
Osteoimmunology: Cross-talk between Bone and Immune Cells

The complexity of skeletal system has long been appreciated for its roles in support and regulation of mineral homeostasis. However, with increasing knowledge of the intercommunication among the various cell types associated with bone, a deeper appreciation of the dynamic role of the skeleton has unfolded. The cells of bone were classically identified as the bone forming osteoblasts, the osteocytes embedded in the mineral matrix, and the bone resorbing osteoclasts. As more information became available regarding the origin of these cells, it became increasingly apparent that there were not only important control mechanisms within the skeletal system, but also with the immune system. Although the term ‘‘osteoimmunology’’ was first used in a published commentary by Aaron and Choi in 2000, observations that cells of the immune system could be involved in the regulation of bone cell action date back to 1972 (Aaron & Choi, 2000). This study by Horton et al. (1972) noted that a soluble mediator present in supernatant fluid from cultures of human peripheral blood leukocytes that were stimulated by phytohemagglutinin, or by antigenic material found in human dental plaque, could increase the number of active osteoclasts and stimulate bone resorption in fetal rat bone organ cultures. This factor was initially called osteoclast-activating factor (OAF) but was later identified as the cytokine, IL-1 beta (Dewhirst et al., 1985). IL-1 is now recognized as a major player in the regulation of osteoclastic as well as osteoblastic mediated responses particularly in inflammatory conditions. Since then, a number of cytokines and chemokines produced by a variety of cells associated with the immune system have been identified as modulators of bone cells. The article by Souza & Lerner (2013) in this thematic issue provides a comprehensive review of the wide variety of the factors produced in inflammatory processes that have both positive and negative effects on osteoclastic
Medical Ethnocentrism and the Treatment of Addiction

The challenge is how to attain, how to maintain, and how to restore a unified concept of man in the face of the scattered data, facts and findings supplied by a compartmentalized science of man.... What is dangerous is the attempt of a man who is an expert, say, in the field of biology, to understand and explain human beings exclusively in terms of biology. The same is true of psychology and sociology as well. At the moment at which totality is claimed, biology becomes biologism, psychology becomes psychologism, and sociology becomes sociologism. In other words, at that moment science is turned into ideology. Viktor E. Frankl. 1
VsrA, a second two-component sensor regulating virulence genes of Pseudomonas solanacearum

The wilt-inducing phytopathogen Pseudomonas solanacearum produces several extracellular virulence factors, both polysaccharides (EPS I) and proteins (EXPs), which are independently regulated by a LysR-type transcriptional regulator, PhcA, and a histidine kinase sensor, VsrB. Here we characterize a third locus, vsrA, which is also required for normal production of EPS I, some EXPs and wilt disease. Analysis of eps::lacZ reporters in vsrA mutants showed that, like vsrB and phcA, vsrA is required for maximal expression (transcription) of eps, which contains some of the genes necessary for production of EPS I. Unlike vsrB and phcA mutants, however, eps transcription (and EPS I production) by vsrA mutants varies from 3 to 17% of wild-type levels, depending on growth conditions. Inactivation of vsrA also causes a dramatic reduction in production of three species of EXPs (28 kDa, 48 kDa, and 66 kDa), and an apparent increase in production of a few other EXPs. Unlike most other EPS-deficient P. solanacearum strains, vsrA mutants caused almost no disease symptoms when 10(4) cells were stem-inoculated into tomato plants. This correlated with a greater than 10-fold reduction in their ability to grow in planta. vsrA was cloned from a P. solanacearum genomic library by complementation of the vsrA mutant and was further subcloned on a 2.3 kb DNA fragment. PhoA fusion analysis and subcellular localization of the vsrA gene product in Escherichia coli maxicells suggest that it is a 53 kDa membrane-associated protein. Analysis of the nucleotide sequence of vsrA revealed a 502 residue open reading frame with homology to the histidine kinase domain of sensors in the two-component regulator family. This discovery shows that EPS I production by P. solanacearum is simultaneously controlled by dual two-component sensors.
Sparse channel estimation via matching pursuit with application to equalization

Channels with a sparse impulse response arise in a number of communication applications. Exploiting the sparsity of the channel, we show how an estimate of the channel may be obtained using a matching pursuit (MP) algorithm. This estimate is compared to thresholded variants of the least squares (LS) channel estimate. Among these sparse channel estimates, the MP estimate is computationally much simpler to implement and a shorter training sequence is required to form an accurate channel estimate leading to greater information throughput.
Assertive Community Treatment: Twenty-Five Years of Gold

Editor's Note: In the commentary below, Lisa Dixon, M.D., M.P.H., discusses the arti- cle on page 755, reprinted from the October 1974 issue of Hospital and Community Psy- chiatry. That article described an innova- tive, two-year-old program in Madison, Wis- consin, that received a Gold Achievement Award in 1974 from the American Psychi- atric Association. Citing numerous articles from this journal, Dr. Dixon shows how the award-winning program, which was the first to use what is now called assertive commu- nity treatment, captured the attention of practitioners and researchers and shaped the delivery of mental health care over the past 25 years. (Psychiatric Services 51:759- 765, 2000)
New adducts of 1,3,5‐trinitro‐1,3,5‐triazacyclohexane (RDX)

Relatively stable equimolar adducts of 1,3,5-trinitro-1,3,5-triazacyclohexane were prepared with 2,6-lutidine-N-oxide, 4-hydroxy-1-butanesulfonic acid δ-sultone (1,4-butane sultone), and 2,2,6,6-tetramethyl-4-piperidone-1-oxyl. Only the last adduct is selective for RDX; the others also form adducts with 1,3,5,7-tetranitro-1,3,5,7-tetrazacyclooctane. A very labile RDX adduct is formed with tetrahydrothiophene-1-oxide. Some properties of the new adducts are presented.
Quantitative response of volumetric variables measured by a new ultrasound dilution method in a juvenile model of hemorrhagic shock and resuscitation.

Abstract Objective New volumetric variables of preload, such as total end-diastolic volume index (TEDVI) and active circulation volume index (ACVI) and central blood volume index (CBVI), may represent good indicators of preload and predictors of fluid responsiveness. During acute changes of intravascular volume these variables would allow a more accurate intervention. Aim The aim of the present study was to investigate the changes in TEDVI, ACVI, CBVI in a juvenile model of hemorrhagic shock and resuscitation. Methods Twelve anaesthetized ponies (3–8 months of age) were studied at normovolaemia (BASE), after blood withdrawal to mean arterial pressure (MAP) of 40 mmHg (HEMO), after infusion of norepinephrine to reach a MAP of ±10% of baseline (HE-NE), and after retransfusion of shed blood (RESU). TEDVI, ACVI, CBVI were measured by Ultrasound Dilution (UD) technology with CoStatus device. Data were analyzed using 1-way (ANOVA) followed by Bonferroni's multiple pairwise comparisons. Evaluation of dependence between CoStatus volumetric variables and stroke volume index (SVI) were performed using the linear regression analysis and calculating the r 2 coefficient of determination. Results TEDVI and ACVI changed significantly during HEMO and RESU status. NE administration induced MAP and CVP significant changes, whereas TEDVI and ACVI remained unchanged. CBVI showed high variability and seemed to be inconsistent on the identification of the volume status. In the correlation analysis, only TEDVI consistently correlated with SVI and volume induced SVI changes. Conclusions In this animal model, TEDVI and ACVI were superior to CBVI in consistently reflecting hemorrhage. TEDVI but not ACVI and CBVI correlated with volume-induced changes in SVI. NE administration did not affect this correlation.
Ophthalmic presentation in the emergency department: a case report of a girl with "shimmering eyes".

Abstract Background Ophthalmic complaints are commonplace in the emergency department (ED) and are often initial presentations of a systemic illness. We present a 2-year-old girl presenting to the ED with ataxia and “shimmering” eyes. Case Report The patient was diagnosed with opsoclonus-myoclonus syndrome (OMS) involving involuntary, multi-vectorial (mostly horizontal), conjugate fast eye movements without intersaccadic intervals. The ophthalmic presentation led to a paraneoplastic work-up, which revealed an abdominal mass measuring 5.3 × 3.3 × 4.3 cm, suggestive of neuroblastoma. The patient's opsoclonus improved after a 5-day course of dexamethasone and intravenous immunoglobulin. Why should an emergency physician be aware of this? This case illustrates the importance of recognizing pathognomonic ophthalmic complaints in the ED. We present an overview of classic ophthalmic presentations associated with systemic illnesses.
Optimal pulses for ultra-wide band communication systems on gaussian and dense multi-path channels

In this paper, we first present several propositions which show how to find optimal pulses for UWB systems using PPM on Gaussian channels. The optimization has been done in term of minimizing bit error rate (BER) for a given modulation index. Using the new pulses the BER performance can be improved by 0.4-0.7 dB. Furthermore, numerical results show that similar performance improvement can be obtained over the multipath channels
Annual Research Review: Building a science of personalized intervention for youth mental health

Background Within the past decade, health care service and research priorities have shifted from evidence-based medicine to personalized medicine. In mental health care, a similar shift to personalized intervention may boost the effectiveness and clinical utility of empirically supported therapies (ESTs). The emerging science of personalized intervention will need to encompass evidence-based methods for determining which problems to target and in which order, selecting treatments and deciding whether and how to combine them, and informing ongoing clinical decision-making through monitoring of treatment response throughout episodes of care. We review efforts to develop these methods, drawing primarily from psychotherapy research with youths. Then we propose strategies for building a science of personalized intervention in youth mental health. Findings The growing evidence base for personalizing interventions includes research on therapies adapted for specific subgroups; treatments targeting youths’ environments; modular therapies; sequential, multiple assignment, randomized trials; measurement feedback systems; meta-analyses comparing treatments for specific patient characteristics; data-mining decision trees; and individualized metrics. Conclusion The science of personalized intervention presents questions that can be addressed in several ways. First, to evaluate and organize personalized interventions, we propose modifying the system used to evaluate and organize ESTs. Second, to help personalizing research keep pace with practice needs, we propose exploiting existing randomized trial data to inform personalizing approaches, prioritizing the personalizing approaches likely to have the greatest impact, conducting more idiographic research, and studying tailoring strategies in usual care. Third, to encourage clinicians’ use of personalized intervention research to inform their practice, we propose expanding outlets for research summaries and case studies, developing heuristic frameworks that incorporate personalizing approaches into practice, and integrating personalizing approaches into service delivery systems. Finally, to build a richer understanding of how and why treatments work for particular individuals, we propose accelerating research to identify mediators within and across RCTs, to isolate mechanisms of change, and to inform the shift from diagnoses to psychopathological processes. This ambitious agenda for personalized intervention science, although challenging, could markedly alter the nature of mental health care and the benefit provided to youths and families.
Dissection, Staining, and Mounting of the Embryos of Conifers

A statement is given of the advantages of this special technic and its place in embryological investigations, including directions for selecting the proper stages in collecting conifer cones and ovules, their methods of dissection from living material and their preservation for later dissection. The choice of dissecting microscopes and dissecting instruments, as well as directions for staining embryos with phloxine which may be combined with slow dehydration in glycerin, or for staining with Delafield's or Heidenhain's hematoxylin which may be followed by the glycerin dehydration are described. Glycerin affords a convenient break for a temporary stopping place in this technic.Directions are given for transfer from glycerin thru 95% and absolute ethyl alcohol into other solvents such as diaphane solvent, essence of euparel or an easily prepared sandarac solvent. Other mounting media which have been used for conifer embryos are discussed—glycerin jelly, Venetian turpentine and Canada balsam—emphasizing the ...
A phase II trial of pemetrexed in patients with recurrent thymoma or thymic carcinoma

7079 Background: Few prospective trials have been conducted in patients with advance thymic malignancies. Pemetrexed a multi-targeted antifolate with a broad range of clinical activity, but previously untested in thymic malignancies. As a result, a phase II trial was initiated to evaluate the clinical activity of pemetrexed in previously treated patients with thymoma (THY) and thymic carcinoma (TC). Methods: From February, 2005 to November, 2005, twenty-seven previously treated patients with unresectable stage IVA (n = 16) or stage IVB (n =11) disease were treated with pemetrexed at a dosage of 500 mg/m2 every three weeks for a maximum of 6 cycles or until undue toxicity or progressive disease. All patients received folic acid, vitamin B12 and steroid prophylaxis. Profile of patients include: median age = 52 years (range 26–84); M: F = 13:14; PS 0/1= 17/10; median number of prior therapies = 2 (range 1–6); 21 had prior radiation therapy; and histology (THY = 16, TC = 11). Results: The median number of cyc...
Deepen research on electric load modelling

Detailed procedures for the modelling of synthesis load of practical power network are presented; then based on the detailed investigation and statistics of load composition at 220 kV and 330 kV substations, the distribution of different kinds of load in domestic power grids are analyzed and the necessity of establishing the parameters of synthesis load model (SLM) suitable to actual power networks is pointed out; finally, the influence of SLM parameters on stability of interconnected power grids is researched. Research results show that it is crucially important for accurate analysis on power grid stability to choose appropriate load model and parameters.
Isolation of Dehydroepiandrosterone-C14 from Dogs Infused with Cholesterol-4-C14 by the Spermatic Artery.∗

SummaryDehydroepiandrosterone-C14 has been isolated in spermatic vein blood of anesthetized dogs infused with cholesterol-4-C14 by the spermatic artery. It is considered that this finding lends additional support to the view that dehydroepiandrosterone is an intermediate in the biosynthesis of testicular androgens.
Design and Implementation of the Enterprise Personnel Management System Based on B/S

With the rapid development of computer and network technology, the traditional manual management mode of the enterprise personnel department has been unable to adapt to the growing demand for human resources management of the modern enterprise. The system uses My Eclipse development environment and SQL Server database, and develops an enterprise personnel management system based on B/S structure. The system has the characteristics of friendly interface, simple operation,stable running,and can greatly improve the work efficiency of the enterprise personnl management.
Surveillance result of natural foci of Microtus fuscus in Sichuan Province from 2000 to 2012

Objectives To analysis epidemic trend of natural foci of Microtus fuscus in Sichuan Province and provide the countermeasure for plague prevention and control.Methods The data of plague surveillance in Sichuan Province from 2000 to 2012 were collected and analyzed.Results The investigation showed an average density of Microtus fuscus of 253.27rats per hectare,9 kinds of fleas were discovered in Microtus fuscus bodys and lairs,The Callopsylla sparsicis and Amphipsylla tuta were main fleas(93.21%).The other fleas accounted for 6.69%,Body flea index was 0.90,infection rate of fleas was 42.48%,every lair of Microtus fuscus had the fleas,nest flea index was 53.65.Fourteen thousand three hundred and twenty-three data of host animals were collected in laboratory,98 trains Y.pestis were detected;twenty-six thousand four hundred and eleven fleas of 2455 groups were examined,11 strains of Y.pestis were detected.There were 8 animals and 3 vector fleas were infected.Three thousand three hundred and sixty-nine animal serums were examined by IHA method and 215 were positive with 102 positive Microtus fuscus serums,94 dog serums and other 19 animal serums.Conclusion Since 2000,natural Foci of Microtus fuscus in Sichuan Province has been active state.The results showed that propaganda and surveillance work of plague control and prevention should be strengthened.
Evaluation of Tuberculosis Health Education Among 1305 Middle School Students in Fengxiang County of Shaanxi Province

Objective:Discussing the methods to develop tuberculosis health education activities about among middle school students by investigating the awareness rate of basic knowledge concerning tuberculosis and the government's free treatment policy.Methods:Health education program concerning key knowledge of tuberculosis was carried out among 1342 students from a middle school in Fengxiang County randomly selected by cluster sampling,then the results of questionares before and after the program were compared.Results:Before the health education program,47.59% of the students heared about tuberculosis,50.42% of the studnts knew the infectiousness of tuberculosis,the awareness rate of the main symptoms of tuberclossis was from 22.99% to 38.77% and that of the transmission route was 24.83%,and 24.83% of the students knew the free treatment policy.After health education intervation,85.11% of the students knew that tuberculosis was infectious,the awareness rate of the main symptoms of tuberclossis was from 62.60% to 84.05% and that of the transmission route was 70.22%,and 81.48% of the students knew the free treatment policy.The percentage of stuents who were aware of the basic knowledge concerning tuberculosis was improved significantly(P0.05 or P0.01).Conclusions:Health education can significantly raise the awareness rate of basic knowledge concerning tuberculosis prevention and treatment among middle school students.
Visual exploration of machine learning results using data cube analysis

As complex machine learning systems become more widely adopted, it becomes increasingly challenging for users to understand models or interpret the results generated from the models. We present our ongoing work on developing interactive and visual approaches for exploring and understanding machine learning results using data cube analysis. We propose MLCube, a data cube inspired framework that enables users to define instance subsets using feature conditions and computes aggregate statistics and evaluation metrics over the subsets. We also design MLCube Explorer, an interactive visualization tool for comparing models' performances over the subsets. Users can interactively specify operations, such as drilling down to specific instance subsets, to perform more in-depth exploration. Through a usage scenario, we demonstrate how MLCube Explorer works with a public advertisement click log data set, to help a user build new advertisement click prediction models that advance over an existing model.
Network Aware Reliability Analysis for Distributed Storage Systems

It is hard to measure the reliability of a large distributed storage system, since it is influenced by low probability failure events that occur over time. Nevertheless, it is critical to be able to predict reliability in order to plan, deploy and operate the system. Existing approaches suffer from unrealistic assumptions regarding network bandwidth. This paper introduces a new framework that combines simulation and an analytic model to estimate durability for large distributed cloud storage systems. Our approach is the first that takes into account network bandwidth with a focus on the cumulative effect of simultaneous failures on repair time. Using our framework we evaluate the trade-offs between durability, network and storage costs for the OpenStack Swift object store, comparing various system configurations and resiliency schemes, including replication and erasure coding. In particular, we show that when accounting for the cumulative effect of simultaneous failures, the probability of data loss estimates can vary by two to four orders of magnitude.
Milling quality and rheological properties of two selected local and newly introduced rice cultivars; impacted by drying parameters and milling system

Various postharvest parameters have an impact on the milling quality and rheological properties of rice. The objective of this study was to appraise the whole rice kernel percentage and pasting properties of local and newly introduced rice cultivars as affected by drying air temperature, grain final moisture content and type of rice whitener. The results of whole kernel percentage (WKP) indicated the superiority of abrasive type whitener over the friction type whitener. Bending strength had significant negative correlation with chalkiness, length, width and length to width ratio of grain. There was no significant correlation between WKP and bending strength. For Gohar, results showed that the drying parameters and type of whitener has a significant effect on final, breakdown, and setback viscosity. These differences, however, were not significant for Hashemi. Furthermore, the highest level of the breakdown viscosity and final viscosity was observed for severe drying accompanied with friction type whitener, while the lowest level of final viscosity was belonged to low temperature drying and abrasive type whitener. So drying parameters and milling system can be effect on milling quality and rheological properties of some rice cultivars.
Luanda – A spatial national metonymy in O herói and Na cidade vazia

Through the analysis of the Angolan films O heroi/The Hero (2004) and Na cidade vazia/The Hollow City (2004), this study identifies the filmic depictions of Luanda as a critical site for understanding the continuous struggles of the nation to form itself, to overcome the challenges left by its colonial legacy, and to address those that arise from its internal sociopolitical struggles. To this end, I focus particularly on the spatial representations of the Luanda and how they render the growing inequity of Angolan society visible, as well as revealing a milieu that consistently erects obstacles to the completions of the protagonists’ ambitions. Lastly, the films’ distinct temporal settings allow us to assess different historical perspectives of these ongoing individual and societal processes, which includes discrete idealized and projected outcomes for the nation.
Manufacture of a 1.7m prototype of the GMT primary mirror segments

We have nearly completed the manufacture of a 1.7 m off-axis mirror as part of the technology development for the Giant Magellan Telescope. The mirror is an off-axis section of a 5.3 m f/0.73 parent paraboloid, making it roughly a 1:5 model of the outer 8.4 m GMT segment. The 1.7 m mirror will be the primary mirror of the New Solar Telescope at Big Bear Solar Observatory. It has a 2.7 mm peak-to-valley departure from the best-fit sphere, presenting a serious challenge in terms of both polishing and measurement. The mirror was polished with a stressed lap, which bends actively to match the local curvature at each point on the mirror surface, and works for asymmetric mirrors as well as symmetric aspheres. It was measured using a hybrid reflective-diffractive null corrector to compensate for the mirror's asphericity. Both techniques will be applied in scaled-up versions to the GMT segments.
Synthesis and Reactivity of Pyridine(diimine) Molybdenum Olefin Complexes: Ethylene Dimerization and Alkene Dehydrogenation

Reduced pyridine(diimine) molybdenum olefin complexes have been synthesized and structurally characterized. Examples with 1,5-cyclooctadiene, (PDI)Mo(η2:η2-1,5-COD) (COD = 1,5-cyclooctadiene) adopt a distorted-trigonal-bipyramidal geometry and are best described as low-spin Mo(II) compounds arising from significant π back-donation to the ligand from a reduced molybdenum center. With the 2,6-diisopropyl N-aryl-substituted variant of the pyridine(diimine) ligand, a molybdenum bis(ethylene) complex was obtained. Reducing the size of the N-aryl substituents to 2,4,6-trimethyl resulted in isolation of (MesPDI)Mo(η4-butadiene)(η2-ethylene) following sodium amalgam reduction of the corresponding molybdenum(III) trichloride complex in the presence of excess ethylene. Analysis of the byproducts of the reaction and olefin addition experiments demonstrate that butadiene formation is consistent with a pathway involving ethylene coupling to form 1-butene followed by allylic dehydrogenation to produce butadiene. Excess...
Countries’ geographic latitude and their human populations’ cholesterol and blood pressure

Background: In the 1980s, analysis of 30 countries suggested that people living farther from the Equator had a higher incidence of cardiovascular disease. Some have hypothesized that sunlight plays a role. Methods: We analyzed 180 or more countries′ age-standardized average cholesterol, age-standardized mean systolic blood pressure (BP), and age-standardized prevalence of raised BP, by geographic latitude, over decades. In addition to latitude, we performed analysis by ultraviolet B light (UVB) exposure averaged over several years. Results: Mean cholesterol increases with the distance of a country from the Equator. This relationship has changed very little since 1980. Similarly, in 1975, mean systolic BP and prevalence of raised BP were higher in countries farther from the Equator. However, the relationship between latitude and BP has changed dramatically; by 2015, the opposite pattern was observed in women. Countries′ average UVB exposure has a stable relationship with cholesterol over recent decades, but has a changing relationship with BP. Conclusions: Since sunlight exposure in a country is relatively fixed and its relationship with BP has changed dramatically in recent decades, countries′ average sunlight exposure is an unlikely explanation for contemporary country-level variation in BP. However, our findings are consistent with a putative effect of sunlight on countries′ average cholesterol, as well as a no longer detectable effect on BP decades ago. A parsimonious potential explanation for the relationship between light and cholesterol is that 7-dehydrocholesterol can be converted to cholesterol, or in the presence of ultraviolet light, it can instead be converted to vitamin D.
Bundle min-Hashing

We present a feature bundling technique based on min-Hashing. Individual local features are aggregated with features from their spatial neighborhood into bundles. These bundles carry more visual information than single visual words. The recognition of logos in novel images is then performed by querying a database of reference images. We further present a WGC-constrained ransac and a technique that boosts recall for object retrieval by synthesizing images from the original query image or reference images. We demonstrate the benefits of these techniques for both small object retrieval and logo recognition. Our logo recognition system clearly outperforms the current state-of-the-art with a recall of 83 % at a precision of 99 %.
Vicarious trauma, themes in research, and terminology: A review of literature.

Growth in the arena of trauma-informed care has correspondingly created interest in the potential hazards for clinicians who regularly provide trauma-based services. However, what to call the phenomena of clinicians being affected by bearing witness to other’s trauma is a source of perplexity. A rev
Progress on cubic interactions of arbitrary superspin supermultiplets via gauge invariant supercurrents

Abstract We consider cubic interactions of the form s − Y − Y between a massless integer superspin s supermultiplet and two massless arbitrary integers or half integer superspin Y supermultiplets. We focus on non-minimal interactions generated by gauge invariant supercurrent multiplets which are bilinear in the superfield strength of the superspin Y supermultiplet. We find two types of consistent supercurrents. The first one corresponds to conformal integer superspin s supermultiplets, exist only for even values of s , s = 2 l + 2 , for arbitrary values of Y and it is unique. The second one, corresponds to Poincare integer superspin s supermultiplets, exist for arbitrary values of s and Y .
Thirty-Day Readmission Among Patients With Non-Ventilator Hospital Acquired Pneumonia and Effects on Outcomes

We determine the rate of hospital readmission within 30 days of non-ventilator hospital acquired pneumonia (NV-HAP) and its impact on mortality, morbidity, and health care use in the United States. A retrospective study was conducted using the Agency for Healthcare Research and Quality’s Healthcare Cost and Utilization Project Nationwide Readmission Database for the year 2014 (14.9 million hospital stays at 2048 hospitals in 22 states). 86,601 adulthospital admissions were identified for NV-HAP and discharged. The primary outcome was rate of all-cause readmission within 30 days of discharge. Secondary outcomes were reasons for readmission, readmission mortality rate, morbidity (shock and prolonged mechanical ventilation) and resource use (length of stay and total hospitalization costs and charges). Independent risk factors for readmission were identified using logistic regression analysis. The 30-day rate of readmission was 12.6%. 51%of readmissions were due to recurrent Pneumonia, followed by sepsis (40%). The rate of death among patients readmitted to the hospital (21%) was lower than that for index admissions (26%) (P In this retrospective study of patients hospitalized for NV-HAP, readmission is associated with a high mortality, morbidity, and resource use.