cssi/SciSciGPT-SciSciNet huggingface dataset:
Thermo-mechanical Response and Damping Behavior of Shape Memory Alloy–MAX Phase Composites

NiTi/Ti3SiC2 interpenetrating composites that combine two unique material systems—a shape memory alloy (SMA) and a MAX phase—demonstrating two different pseudoelastic mechanisms, were processed using spark plasma sintering. The goal of mixing these two material systems was to enhance the damping behavior and thermo-mechanical response of the composite by combining two pseudoelastic mechanisms, i.e., reversible stress-induced martensitic transformation in SMA and reversible incipient kink band formation in MAX phase. Equal volume fractions of equiatomic NiTi and Ti3SiC2 were used. Microstructural characterization was conducted using scanning electron microscopy to study the distribution of NiTi, Ti3SiC2, and remnant porosity in the composite. Thermo-mechanical testing in the form of thermal cycles under constant stress levels was performed in order to characterize shape memory behavior and thereby introducing residual stresses in the composites. Evolution of two-way shape memory effect was studied and related to the presence of residual stresses in the composites. Damping behavior, implying the energy dissipation per loading–unloading cycle under increasing compressive stresses, of pure NiTi, pure Ti3SiC2, as-sintered, and thermo-mechanically cycled (TC) NiTi/Ti3SiC2 composites, was investigated and compared to the literature data. In this study, the highest energy dissipation was observed for the TC composite followed by the as-sintered (AS) composite, pure NiTi, and pure Ti3SiC2 when compared at the same applied stress levels. Both the AS and TC composites showed higher damping up to 200 MPa stress than any of the metal—MAX phase composites reported in the literature to date. The ability to enhance the performance of the composite by controlling the thermo-mechanical loading paths was further discussed.
Estrogen preconditioning protects the hippocampal CA1 against ischemia

Abstract Estrogen is neuroprotective against ischemia in both in vivo and in vitro injury models. Because of the promising preclinical data on neuroprotection, the Women’s Estrogen for Stroke Trial was initiated. The outcomes from this trial were, however, unsuccessful and questions emerged about the safety of chronic estrogen treatment in women. In contrast to the chronic estrogen treatment strategy, the present study aims to investigate: (1) the neuroprotective efficacy of single estrogen pretreatment/preconditioning; and (2) the existence of a similarity between estrogen- and ischemic preconditioning-induced neuroprotection against cerebral ischemia. The efficacy of estrogen was tested in an in vitro model of cerebral ischemia using hippocampal organotypic slice culture system. The hippocampal organotypic slice cultures were generated from female neonatal (9–11 days old) Sprague-Dawley rats. The slices were exposed to estradiol-17β (0.5, 1, 5 nM) for various durations (1, 2 or 4 h) 48 h prior to ischemia (40 min of oxygen-glucose deprivation). For ischemic preconditioning, slices were exposed to sublethal oxygen-glucose deprivation (15 min), 48 h prior to lethal oxygen-glucose deprivation. Quantification of cell death in hippocampal CA1 region was conducted by using propidium iodide fluorescence staining technique. Results demonstrated that estrogen preconditioning significantly protects the hippocampal CA1 region against ischemia ( P n =15), 18±2 (5 nM; 4 h; n =12), 32±3 ( n =8), 65±3 ( n =27), respectively. Further, estrogen preconditioning initiated a calcium-mediated signaling pathway leading to protection of CA1 neurons against ischemia. Future investigations in estrogen preconditioning may suggest new estrogen regimens that avoid potential side effects of chronic estrogen treatment for stroke patients.
Condom Use Negotiation in Heterosexual African American Adults: Responses to Types of Social Power-Based Strategies

This study examined gender differences and preferences in the use of and response to six different styles of condom use negotiation with a hypothetical sexual partner of the opposite gender. Participants were 51 heterosexually active African American adults attending an inner-city community center. Participants completed a semistructured qualitative interview in which they were presented with six negotiation strategies based on Raven's 1992 Power/Interaction Model of Interpersonal Influence. Results showed that female participants responded best to referent, reward, and legitimate strategies, and worst to informational tactics. Male participants responded best to reward strategies, and worst to coercion to use condoms. Further, responses given by a subset of participants indicated that use of negotiation tactics involving coercion to use condoms may result in negative or angry reactions. Response to strategies may vary with the value of the relationship as viewed by the target of negotiation. Implications...
A chelate-stabilized tungsten–bis­(imido) complex

The title compound, [N,N′-bis­(tri­methyl­silyl)-6,6′-di­methyl­bipheny]-2,2′-di­amido]­bis(2,6-diiso­propyl­phenyl­imido)­tung­sten(VI), [W(C12H17N)2(C20H30N2Si2)], has been synthesized and its crystal structure determined. The geometry around the W atom, imposed by the bi­phenyl­di­amido and bulky 2,6-diiso­propyl­phenyl­imido ligands, is that of a tetrahedron. As a result of this geometry, the bi­phenyl group is twisted, with a dihedral angle of 69.65 (8)°. Principal distances include W—N(imido) 1.762 (2) and 1.772 (2) A, and W—N(amido) 1.976 (2) and 1.984 (2) A.
Reclaiming Alfred Hitchcock Presents

Few would deny that Alfred Hitchcock was the most recognizably famous motion picture director of the twentieth century. This was largely due to the popularity of his films, the cameo appearances he...
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

Methylation of the N(6) position of adenosine (m(6)A) is a posttranscriptional modification of RNA with poorly understood prevalence and physiological relevance. The recent discovery that FTO, an obesity risk gene, encodes an m(6)A demethylase implicates m(6)A as an important regulator of physiological processes. Here, we present a method for transcriptome-wide m(6)A localization, which combines m(6)A-specific methylated RNA immunoprecipitation with next-generation sequencing (MeRIP-Seq). We use this method to identify mRNAs of 7,676 mammalian genes that contain m(6)A, indicating that m(6)A is a common base modification of mRNA. The m(6)A modification exhibits tissue-specific regulation and is markedly increased throughout brain development. We find that m(6)A sites are enriched near stop codons and in 3' UTRs, and we uncover an association between m(6)A residues and microRNA-binding sites within 3' UTRs. These findings provide a resource for identifying transcripts that are substrates for adenosine methylation and reveal insights into the epigenetic regulation of the mammalian transcriptome.
Modeling of Cross-Flow Across an Electrostatically Charged Monolith Filter

The flow field and filtration efficiency of electrostatically charged micro-channel filters under cross-flow conditions were modeled. In our simulations, the fluid flows tangentially to the filter face (cross-flow). Particles with diameters larger than 2 μm were considered in this study, hence, the effects of Brownian motion were not included in the simulations. The influence of particle size, pressure drop, and electrostatic charge on the filtration efficiency was investigated. Measurements from performing electrostatic force microscopy (EFM) on the monolith sample confirmed the presence of charge and gave a qualitative measurement of the charge distribution. Results from the flow simulations indicate that the electrostatic forces increased the particle capture efficiency only at lower pressure drop. At higher pressure drops, electrostatic forces did not significantly increase the capture efficiency of the particles. Also, the capture efficiency of relatively small particles is found to be more dependent...
Statistical study of strength and fatigue life of composite materials

Abstract Fatigue life scattering of glass fibre-reinforced epoxy composites has been studied at 300 K and 77 K. The static strength and the fatigue life distributions were studied using normal, log-normal and two-parameter Weibull distribution functions; the value of mean fatigue life was analysed using mean fatigue life, mean log fatigue life and expected value of the Weibull distribution function. The effect on fatigue life of two stress levels (low-high and high-low) was investigated using the distribution functions; a modification of Miner's rule is made to predict the resulting scattering.
Abstract LB-125: Selective inhibition of CDK7 targets MYCN-driven transcriptional amplification in neuroblastoma

Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Oncogenic MYC family transcription factors act as universal amplifiers of the existing gene expression program in many cancer cells, thus reducing rate-limiting constraints on growth and proliferation. Amplification of the MYCN gene defines approximately 50% of high risk neuroblastomas (NB), and is associated with aggressive disease and a poor clinical outcome. Here we exploit MYCN-driven global transcriptional amplification to specifically target MYCN-deregulated NB cells by inhibiting CDK7, a cyclin-dependent kinase with major roles in transcriptional initiation (as part of the TFIIH complex) and elongation (by activating CDK9/P-TEFb). For this purpose, we chose CDK7-IN-1, a newly developed, highly selective, first-in-class covalent inhibitor of CDK7, and then determined the effects of CDK7 inhibition on MYCN expression and global transcriptional activity. NB cells expressing high levels of MYCN were 10 times more sensitive to CDK7 inhibition than normal cells or NB cells not driven by amplified MYCN. CDK7-IN-1 was more active than its reversible (non-covalent) analogue and two pan-CDK inhibitors, roscovitine and flavopiridol. Cytotoxicity in treated MYCN -amplified NB cells resulted from G2 arrest and apoptosis. We observed a dose-dependent decrease in serine 2, 5 and 7 phosphorylation of RNA Pol II C-terminal domain only in MYCN -amplified NB cells, indicating that CDK7-IN-1 selectively inhibits RNA Pol II-mediated transcriptional initiation and elongation. Growth inhibition was accompanied by downregulation of MYCN and MYCN -associated transcriptional programs. CDK7-IN-1 significantly slowed tumor growth in a xenograft model of MYCN -amplified NB (median growth, 56.8% vs. 100% for vehicle-treated mice, P <0.05; n=6 per group) with tumors showing decreased MYCN expression. Mice remained free of toxicity over 4 weeks of CDK7-IN-1 treatment, suggesting that a therapeutic window may exist for NB cells with high MYCN expression. In conclusion, we show for the first time that selective suppression of MYCN expression and MYCN -associated transcriptional activity can be achieved through CDK7 inhibition, with associated antitumor effects in high-risk NB. Thus, CDK7 inhibition warrants further attention as a potential therapeutic strategy for MYCN-deregulated NB and perhaps other MYC-driven cancers. Citation Format: Edmond Chipumuro, Eugenio Marco, Tinghu Zhang, Camilla Christensen, Nicholas Kwiatkowski, Bandana Sharma, Clark Hatheway, Abigail Altabef, Brian J. Abraham, Kwok-Kin Wong, Guo-Cheng Yuan, Richard A. Young, Nathanael S. Gray, Rani E. George. Selective inhibition of CDK7 targets MYCN-driven transcriptional amplification in neuroblastoma. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr LB-125. doi:10.1158/1538-7445.AM2014-LB-125
Effect of hexachlorobenzene on the specific binding of 2,3,7,8,-TCDD to the hepatic receptor

The ability of HCB to interact with the Ah receptor was investigated in vitro and in vivo. HCB, up to 1.0 μM, was not a potent in vitro competitor for the specific binding of [3H]-TCDD (0.3 nM) to rat hepatic cytosol. Administration of HCB (3000 ppm in the diet) to rats for up to 7 days resulted in a decrease in the specific binding of [3H]-TCDD to hepatic cytosol, as compared to pair-fed control rats. These results suggest that HCB may be able to interact, either directly or indirectly, with the hepatic Ah receptor in vivo.
An optimal distributed algorithm for recognizing mesh-connected networks

In this paper, we consider the problem of recognizing whether a given network is a rectangular mesh. We present an efficient distributed algorithm with an O(N) message and time complexity, where N is the number of nodes in the network. This is an improvement of a previous algorithm presented in Mohan (1990) with a message complexity of O(N log N) and time complexity of O(N1.6). The proposed algorithm is constructive in nature and also assigns coordinates to the nodes of the network.
Graded dilation technique for EUS-guided drainage of peripancreatic fluid collections: an assessment of outcomes and complications and technical proficiency (with video).

Background Although the utility and safety of EUS and EUS-guided FNA is well known, there is a need for more data on outcomes and complications of EUS-guided drainage procedures. Objective To evaluate the rates of technical success, treatment success, and complications of the graded dilation technique for performing EUS-guided drainage of peripancreatic fluid collections (PFCs) in a large cohort of patients. Also, the technical proficiency for performing EUS-guided drainage of PFCs was evaluated. Design A prospective study of all patients undergoing EUS-guided drainage of PFC. Setting A tertiary-referral center. Interventions After passage of a 0.035-inch guidewire into the PFC by using a 19-gauge needle, graded dilation of the tract was sequentially performed by using a 4.5F ERCP cannula, a 10F ERCP inner guiding catheter, and an 8-mm balloon dilator. A transmural stent and/or drainage catheter was then deployed. Main Outcome Measurements To evaluate the technical success, treatment success, and complications of the graded dilation technique. Technical proficiency was evaluated by comparing the procedural duration between the first 25 cases (group A), with a later cohort of patients (group B, n=29) who underwent EUS-guided drainage of a single PFC. Results Sixty patients (41 men; mean age 51 years [range 20-79 years], 6 multiple PFCs) underwent EUS-guided drainage of a PFC (types included 36 pseudocyst, 15 abscess, and 9 necrosis) over a 42-month period. The rates of technical and treatment success were 95% and 93%, respectively. A minor complication of stent migration was encountered in 1 of 60 patients (1.7%). There was no significant difference in patient or clinical characteristics between group A and B patients who were undergoing drainage of a single PFC. Although there was no significant difference in technical or treatment outcome, median procedural duration was significantly shorter for group B than for group A patients (25 vs 70 minutes; P P P = .01), even after adjusting for patient age; serum albumin; type, location, and size of PFCs; drainage modality (stent vs stent plus drainage catheter); and site of endoscopic access for establishing drainage. Conclusions In this study, EUS-guided drainage of a PFC could be performed safely by using the graded dilation technique, with a successful outcome in a majority of patients. Technical proficiency, with regard to procedural duration, improved significantly after the first 25 cases.
Export of Organic Matter from a Coastal Freshwater Wetland to Lake Erie: an Extension of the Outwelling Hypothesis

I tested the hypothesis that seiches in large lakes play a role similar to tides in marine system by exporting detrital carbon from coastal wetlands to adjacent open waters. The study was conducted at a wetland site located along the shore of the Lake Erie. Water samples were collected at the outlet of the marsh, during inflow and outflow events, over a 19-month period. Water isotopes were also measured in the lake and in the marsh to establish the magnitude of the mixing between the two water masses. On average, the concentrations of the outflow water samples was enriched by 7.3 mg DOC l−1 and 3.4 mg POC l−1compared to the inflow water samples, while no difference observed in inorganic carbon fluxes. Organic carbon was exported during fall, winter and early spring which coincide with period of organic matter decomposition. Such a concept of outwelling is not new for marine ecosystem, but is demonstrated in this study for the first time in a large lake setting influenced by seiche events. Ultimately to understand the role that these fluxes may play in maintaining the integrity of the wetland-lake system, it will be necessary to investigate whether the detrital material exported from coastal freshwater wetlands is incorporated into the open lake foodweb.
The final pathogenetic steps in focal bone erosions in rheumatoid arthritis.

The presence of peri-articular osteoporosis and focal bone erosions at the joint margins and within the subchondral bone adjacent to inflamed joints has been considered the radiographic hallmark of rheumatoid arthritis (RA).1-4 In addition, in recent years there has been an increased awareness that RA also produces adverse effects on systemic bone remodelling at sites not directly involved with joint inflammation. Numerous reports have documented that people with RA have reduced axial and appendicular bone mass and that this bone loss is associated with an increased risk of fracture.5-11 Thus, it is possible to identify three distinct patterns of bone loss in RA. These include systemic osteoporosis, juxta-articular osteopenia adjacent to inflamed joints and focal marginal and subchondral bone erosions that are associated directly with inflamed synovial tissues. Each of these disorders represents an example of disturbed skeletal tissue remodelling in which there is a net loss of bone, although the precise mechanisms responsible for the bone loss in each of these conditions may involve differential cellular and regulatory processes. This review will focus on the mechanisms involved in the pathogenesis of focal bone erosions that are directly associated with the inflammatory synovial lesion. Insights into the processes underlying the development of focal bone erosions in RA have been derived principally from histopathological evaluation of joint tissues from patients with RA and from animal models of inflammatory arthritis. Early studies by Bromley and Woolley demonstrated the presence of multinucleated cells with phenotypic features of osteoclasts in resorption lacunae at the pannus-bone interface.12-14 More recently, in our own studies,15 we have used in situ hybridisation to demonstrate that multinucleate and some mononuclear cells in resorption lacunae at the bone-pannus interface exhibit the entire repertoire of phenotypic markers that are associated with the fully differentiated osteoclast. This includes …
A Cytological Analysis of the Antimetabolite Activity of 5-Hydroxyuracil in Vicia faba Roots

The effects of 5-hydroxyuracil (5-HU) (isobarbituric acid) upon cell elongation, mitosis, and DNA synthesis were studied in Vicia faba roots. 5-HU had no consistent effect upon root elongation. It blocked DNA synthesis (analyzed by photometric measurements of Feulgen dye in nuclei) during the first 6 hours of treatment; the block spontaneously disappeared by the 12th hour of treatment. Uracil and thymine had no effect upon this block of synthesis. Both thymidine and uridine reversed the block in 6 and 9 hours respectively. In all cases blockage of DNA synthesis was followed by inhibition of mitosis (determined by changes in the percentage of cells in mitosis) and resumption of DNA synthesis was followed by resumption of mitosis. Inhibition indices calculated from the mitotic data indicated a competitive relationship between 5-HU and thymidine and 5-HU and uridine. 5-HU is considered to block DNA synthesis by competing with thymidine for sites on enzymes involved in the synthesis. It is suggested that uridine reverses the block in synthesis by undergoing a conversion to thymidine.
Postaccident Mine Communications and Tracking Systems

Recent mine disasters in the U.S. exposed various inadequacies and gaps in mine-safety technology. Congress responded to these tragedies by enacting the Mine Improvement and New Emergency Response Act of 2006 (MINER Act), which resulted in the most significant change to mine-safety laws in 30 years. To help meet the requirements of the MINER Act and to help eliminate future tragedies, the National Institute for Occupational Safety and Health initiated aggressive research programs for developing new, and enhancing existing, mine-safety technologies. A major research emphasis addressed the lack of postaccident communications, which surfaced as a critical deficiency in some disasters. As a result, three communications approaches emerged as viable technologies-enhanced leaky-feeder, wireless-mesh, and medium-frequency systems. This paper describes the operation, application, advantages, and disadvantages of each system, as well as the challenges associated with underground wireless communications.
Edward Schillebeeckx's Creation Theology as a Resource for Ecological Ethics

As the global community becomes increasingly attuned to the disastrous consequences of our long-standing environmental prodigality, Christians and Christian theologians are cultivating theological and ethical responses to the ecological crisis with the goal of fostering life-giving understandings of creation and ecophilic lifestyles. While many theologians and ethicists have heeded this call to read the signs of the environmental times, Schillebeeckx's creation theology remains an underutilized resource for developing an ethical response to this contemporary crisis. This article seeks to offer Schillebeeckx's theology of creation as fertile soil for nurturing an ecological ethic. This article highlights Schillebeeckx's growing ecological concerns, illustrates the connection between Schillebeeckx's theology of creation and his ecological consciousness, and transposes Schillebeeckx's emerging ecological themes into the register of environmental ethics. This ecological ethics emphasizes co-creativity with God in creation, ecological asceticism, following Christ's creational praxis, and actualizing the present practice of the coming kingdom of God.
Reciprocity for multirestricted Stirling numbers

Multirestricted Stirling numbers of the second kind count the number of partitions of a given set into a given number of parts, each part being restricted to at most a fixed number of elements. Multirestricted numbers of the first kind are then defined as elements of the matrix inverse to the matrix of corresponding multirestricted numbers of the second kind. The anomalous sign behavior of these latter numbers makes them impervious to combinatorial analysis. In answer to a conjecture that has remained open for several years, we derive a reciprocity law for multirestricted Stirling numbers using algebraic techniques based on polynomial recursions. As corollaries, we obtain new recurrence relations for multirestricted numbers, and a new algebraic derivation of the reciprocity law for Stirling numbers.
Political Appointments, Civil Service Systems, and Bureaucratic Competence: Organizational Balancing and Executive Branch Revenue Forecasts in the American States

Scholarship on executive politics provides conflicting views about whether staffing administrative agencies through politicized or (politically) autonomous means is the best method for maximizing bureaucratic competence. We offer a theoretical account which maintains that obtaining a proper balance between both types of personnel systems across the supervisory and subordinate levels of an organization will best foster bureaucratic competence. We evaluate our organizational balancing thesis using data on executive branch general revenue fund forecasts in the American states from 1987 to 2002. States with a combination of politically appointed agency executives and merit-selected subordinates generally provide more accurate revenue forecasts than states that possess uniformly politicized personnel selection systems. Conversely, states with a combination of department head–appointed executives and subordinates chosen from an at-will system (i.e., nonmerit) produce more accurate forecasts than states with uniformly autonomous personnel selection systems. Our statistical findings underscore the positive consequences associated with balancing politicized and autonomous means of selecting personnel within hierarchies of political organizations.
Atención al paciente vih/sida: legislación y bioseguridad odontológica en Colombia

The present article describes biosecurity universal norms for dental care, specifically those referred to care of persons with HIV/AIDS, and also it reviews laws and norms at Colombia with respect to the topic. It establishes the routine of evaluating, controlling and preventing accidents at work and infections associated with dental health practices, guaranteeing a better care and quality of life both for patients and for health personnel.
Trade Practices, Credit Ratings, and Regulation of Trading (Perishable Agricultural Commodities Act)

The nature of fresh fruit and vegetable marketing is such that over the years trade practices and special types of businesses have evolved to support the system. These include private firms that supply fresh fruit and vegetable marketers with information on the products and services and on the financial worth and business character of companies with which they do business. Legislation and government regulations designed specifically for this industry have also been developed to prevent unfair trade practices, arbitrate disputes, and punish offenders. Procedures to protect sellers against bad debts in the event that buyers delay or default on payment are also provided. Marketers must still be aware of the special challenges they face in buying and selling produce and take precautions to deal with them.
A trajectory sensitivity approach to parameter disturbance problems in indirect field oriented drive systems

Trajectory sensitivity methods are applied to a nonlinear error model of the indirect field-oriented control system. The resulting sensitivity models provide an efficient, systematic approach to studying parameter disturbance problems. Specific issues addressed include quantifying and predicting torque and system transients, system sensitivity evaluation and comparison, and motor parameter identification. The principal limitation of the method is the restricted range of parameter disturbances. Per-unit disturbances of +or-30% are shown to provide accurate results. >
Rupture of Lisfranc's Ligament in Athletes*

Ligamentous injuries to the tarsometatarsal joints are uncommon and usually result from violent trauma to the forefoot. A more subtle tarsometatarsal injury consisting of an isolated diastasis of the first and second tarsometatarsal rays has recently been described. This injury is thought to be caused by a rupture of Lisfranc's ligament. Nine injuries that occurred during athletics are described. History and physical findings are crucial for arousing the clinician's suspicion for this injury, but confirmation can best be obtained by comparison weight-bearing radiographs; the space between the first and second metatarsal bases may be widened 2 to 5 mm. Nonoperative treatment consisting of casting and the use of crutches for 4 to 6 weeks was successful in returning patients back to athletics; however, the time to return to competition averaged 4 months.
Universal short-distance structure of the single-particle spectral function of dilute Fermi gases

We show that the universal 1/k 4 tail in the momentum distribution of dilute Fermi gases implies that the spectral function A(k ,ω ) must have weight below the chemical potential for large momentum kkF, with observable consequences in radio-frequency spectroscopy experiments. We find that this incoherent spectral weight is centered around ω �− � (k) in a range of energies of order vF k. This "bending back" in the dispersion, while natural for superfluids, is quite surprising for normal gases. This universal structure is present in the hard-sphere gas as well as in the Fermi-liquid ground state of the highly imbalanced, attractive gas near unitarity. We argue that, even in the BCS superfluid, this bending back at large k is dominated by interaction effects which do not reflect the pairing gap.
Enhancement of superconducting properties of textured YBCO using double seeded technique

Isothermal melt texturing is currently a well established technique for manufacturing superconducting bulk materials with high trapped magnetic fields and levitation forces. The technique involves the growth of RE-123 compounds in geometries such as discs and short rods using top seeding of high temperature material such as SmBCO. The technique is relatively simple, however it yields nonuniform microstructure and variable superconducting properties throughout the length of the sample. The top half of the sample is well oriented and possesses good properties, while the bottom half suffers from misorientation, porosity and poor superconducting properties. In this work, the effects of using top and bottom seeding on microstructure and crystal orientation were studied. We also measured trapped magnetic fields throughout the thickness of the sample. In this arrangement, we found that both top and bottom parts of the sample are well oriented and the trapped magnetic fields in both halves are almost the same. These results give promise to the use of this technique to improve the superconducting properties in bulk textured YBCO.
The Vocabulary of Prometheus Bound

A few years ago, as part of an investigation of the authenticity of Prometheus Bound , I published figures for the occurrence of non-Aeschylean words in that play, as compared with two undisputedly Aeschylean plays ( Th., Pers. ) and with one Sophoclean play ( Aj. ) The figures showed that Prom , contained a greater number of words not found elsewhere in the surviving plays of Aeschylus ( Eigenworter ); and also that, like Soph. Aj. , but unlike the six undisputed plays of Aeschylus, it contained a relatively large number of Eigenworter that occur more than once in the play, some of them quite common and familiar words. The discrepancy between Prom , and the two Aeschylean plays chosen for comparison was quite marked; and the high rate of repeated Eigenworter for Soph. Aj. seemed to confirm that this criterion might be a good one for distinguishing unAeschylean characteristics in a non-Aeschylean play. But the sample was very small, and I was conscious that the criterion (or the particular application of it) was somewhat arbitrary; I was therefore not very confident of the value of my findings.
Hammertoe correction with k-wire fixation.

Background:Kirschner wire (K-wire) fixation for correction of hammertoe deformity is a common, low-cost method for fixation of hammertoes after proximal interphalangeal (PIP) arthroplasty or fusion. Complications of this procedure include pin-tract infection, pin migration, pin bending or breakage, and recurrence of deformity. The investigators reviewed a large experience using K-wire stabilization for hammertoe correction.Methods:All hammertoe corrections performed by a single surgeon from 1999 to 2013 were retrospectively reviewed. A resection arthroplasty of the PIP joint or PIP fusion was performed and fixed with a K-wire. Follow-up duration, preoperative diagnosis, pin duration, concomitant procedures, recurrence rates, and complications were reviewed and analyzed. A total of 1,115 operations were performed on 876 patients, with correction of 2,698 hammertoes. There were 709 female and 167 male patients, with an average age of 57.5 years (range, 14-88 years), followed for an average of 20.8 months (r...
Wire number breakthrough for high-power annular z pinches and some characteristics at high wire number

Characteristics of annular wire array z pinches as a function of wire number and at high wire number are reviewed. The data, taken primarily using aluminum wires on Saturn, are comprehensive. The experiments have provided important insights into the features of wire-array dynamics critical for high X-ray power generation, and have initiated a renaissance in z pinches when high numbers of wires are used. In this regime, for example, radiation environments characteristic of those encountered during the early pulses required for indirect-drive ICF ignition on the NIF have been produced in hohlraums driven by X rays from a z pinch, and are commented on here.
The Poverty of the Sociology of Deviance: Nuts, Sluts, and Preverts

There are three theoretical and ideological biases in the field of the sociology of deviance. (1) Despite the attempt to show that the “deviant” is not different from the rest of us, the very emphasis on his identity and subculture may defeat that aim. (2) Certain forms of “deviance,” especially by the economic and political elite, are neglected. (3) The substantive analyses of sociologists of deviance contain no exploration of the role of power in the designation of “deviance,” despite their many statements to the contrary.
A stub multi-homing solution for IPv6 networks

Multi-homing is one of the primary causes for the exponential growth rate of the global routing table (GRT). This work proposes a stub multihoming solution called Multi-Addressing with Stub Tunnels (MAST). By combining IPv6 multi-addressing with backup tunnels between a stub and each of its providers, stubs can enjoy the reliability advantages of multihoming without adding to the size of the GRT. An analysis of the current Internet BGP RIBs was conducted. It showed that the current global routing table size of 450K prefix entries would be reduced to about 24K entries if the MAST solution was adopted by all stubs.
Mollamides B and C, Cyclic hexapeptides from the indonesian tunicate Didemnum molle.

Two new cyclic hexapeptides, mollamides B (1) and C (2), were isolated from the Indonesian tunicate Didemnum molle along with the known peptide keenamide A (3). The structures were established using 1D and 2D NMR experiments. The relative configuration of mollamide B at the thiazoline moiety was determined using molecular modeling coupled with NMR-derived restraints. Their absolute configuration was determined using Marfeyʼs method. The new peptides have been evaluated for their antimicrobial, antimalarial, anticancer, anti-HIV-1, anti-Mtb, and anti-inflammatory activities. Keenamide A and mollamide B show cytotoxicity against several cancer cell lines.
Alternative Interpretations of Crystal-Line Phase Infrared Dichroic Data from Polyethylene Blown Films-Comprison with X-Ray Results:

High density polyethylene (HDPE) blown films were prepared to examine the effect of increasing take-up ratio (TUR) on crystalline morphology. Infrared dichroic results from those films indicated alignment of the crystalline α-axis along the MD with increasing TUR. While this data concurs with models proposed by previous authors, it conflicts with X-ray scattering results. A model is proposed that rationalizes similar apparent inconsistencies between IR and X-ray data previously reported in the literature.
Transscrotal approach to testicular tumors: An anatomical approach

Performing a conventional radical inguinal orchiectomy for suspected testicular cancer has three important deficiencies: 1) A benign lesion can unnecessarily and unknowingly be treated by orchiectomy. 2) Alternate routes of tumor dissemination (superficial external pudendal veins) are not clamped or destroyed before the tumor-bearing testis is brought up through the external inguinal ring. 3) The act of squeezing the testis through the external inguinal ring may be an important cause of tumor spread. Presented in this paper is a transscrotal approach that eliminates these three deficiencies. It is advocated for critical clinical evaluation.
The effect of data windows on the estimation of free oscillation parameters

Summary In seeking to estimate the frequencies, decay rates, amplitudes and phases of the free oscillations of the Earth using observed seismic spectra, data windows are required to reduce the effects of mode—mode interference. Formal expressions for the variances and covariances of these estimated parameters are derived here, for the case of a single isolated mode and an arbitrary data window. Explicit results are given for a Hann and Blackman—Harris minimum four-term window as well as for a boxcar. The optimum or minimum variance record length for measuring frequencies and decay rates using a Hann window is 1.1 Q-cycles, and that for determining amplitudes and phases is 0.5 Q-cycles.
Clinical Characteristics of Sarcoid Arthropathy: A Population‐Based Study

Objective The epidemiology and clinical characteristics of sarcoid arthropathy are not well described, as only referral-based studies have been reported. This study aimed to use the data from a geographically well-defined population to characterize the clinical characteristics of sarcoid arthropathy. Methods An inception cohort of patients with incident sarcoidosis in the years 1976-2013 in a geographically well-defined population was identified based on comprehensive individual medical records review. Inclusion required physician diagnosis supported by histopathology and radiologic features of intrathoracic sarcoidosis, compatible clinical presentation, and exclusion of other granulomatous diseases. Patients with joint pain were then identified from this cohort. Results In 1976-2013, all 345 incident cases of sarcoidosis were identified. Symptoms of joint pain occurred in 42 patients (mean age 41.2 years, 57.1% female, and 95% white), and 35 patients had swollen joint(s) on physical examination. Most patients had arthralgia prior to the diagnosis of sarcoidosis, with an average time to diagnosis of 21 days. Of the 35 cases, oligoarthritis (2 to 4 joints) was the most common pattern (88% of cases), followed by monoarthritis (6%) and polyarthritis (6%). Ankles were involved in 91% of cases. In the majority of patients (88%), the arthritis resolved within 6 weeks. Classic Lofgren's syndrome was observed in 11 patients (26%). Conclusion Inflammatory arthritis occurs in a minority of patients with sarcoidosis. Acute oligoarthritis with bilateral ankle involvement was the most common pattern of sarcoid arthropathy. It should be noted that the generalizability of the results may be limited, as the cohort was predominantly white.
The Management of Archival Institutions

OVER the past several years we have all heard considerable talk about the deplorable state of reporting by our archival agencies. There seems to be general agreement that too few institutions develop such reports and that too few of those prepared are printed or otherwise reproduced for distribution. The annual report of the Archivist of the United States has come in for its share of this discussion. There is no question that something has happened to the National Archives report. From a high of almost 70 pages 25 years ago our annual accounting is now reduced to a 4or 5-page section of the report to Congress by the Administrator of General Services. We recognize that this accounting is an inadequate report to our profession. It should and will be supplemented; and I, for one, am not unhappy at the prospect of separating our administrative from our professional report. But tonight I am interested in the question of periodic reporting by our archival agencies only as a pretext for my subject. Since we have not been reporting to you in detail I felt that it would not be amiss if I talked to you about the National Archives. I propose to do so from a somewhat novel point of view—the point of view of the management of an archival institution—a subject, I am sure, that seldom is discussed in any annual report. Many years ago A. R. Newsome in a presidential address to this Society described the American archivist as "a scholar, an expert technician skilled in the arts of his profession, and a public administrator." Newsome had little to say about the responsibilities of the archivist as a public administrator, and, so far as I know, no one among us has ever spoken on the problems of managing an archival institution as distinct from those of managing archives
Why the Medieval Trial of Joan of Arc is of Particular Interest Today [Book Review]

Professor Tiefenbrun reviews Daniel Hobbins, The Trial of Joan of Arc (Harvard U. Press, 2005). Hobbins translated into English the original Latin rendering of the proceedings of Joan's trial, and provided an introduction placing the trial in historical and legal context. The review praises the excellence of Hobbins's book, and argues that the trial itself has continued relevance today. The review also suggests that Hobbins's book, and study of the trial itself, would be a valuable addition to a variety of law school courses, including Law and Literature, Women's Rights, Human Rights, Comparative Law, Legal History, and others.
Efficient optical coupling into ultra-compact plasmonic slot waveguides using dipole nanoantennas

Nanoantenna is used for coupling free space radiation to subwavelength plasmonic waveguide. We provide a theoretical design of ultra-compact dipole nanoantennas --- Yagi-Uda antenna with a reflector in telecom range and experimentally demonstrate efficient optical coupling between lensed fiber and plasmonic slot waveguide by utilizing our designed nanoantenna. We also prove that the couple-in efficiency of 8% from the lensed fiber does not equal to the couple-out efficiency of 50% from the plasmonic slot waveguide using the same nanoantenna design, which is different than many published and experimental results. We also study the relationship between couple in efficiency and the incident light spot size, which is experimentally characterized.
The Dissembler of John 3: A Cognitive and Rhetorical Approach to the Characterization of Nicodemus

Ancient rhetorical theory and the modern cognitive sciences have been almost entirely overlooked by scholars interested in the characterization of Nicodemus. In an effort to fill these twin lacunae, I approach the characterization of Nicodemus in John 3:1–15 from the vantage point of its rhetorical context, as well as of what we know of how humans make sense of characters. Unsurprisingly, new approaches shed new light on old questions surrounding the characterization of this (in)famous “leader of the Jews.” Viewed from this perspective, informed audience members likely would have viewed Nicodemus as a suspicious dissembling character in his first appearance in John's Gospel, rather than as a “secret” or “imperfect” believer or seeker. This conclusion is supported by the cognition of characterization and the particular variety of figured speech enlisted by the Johannine Jesus in response to Nicodemus. While this article focuses particularly on John 3:1–15, there are compelling reasons to infer that audience members were meant to deduce that Nicodemus was ultimately convinced by Jesus's rhetorically savvy response (cf. 7:50–51, 19:39).
CRT-200.95 Impella Support Improved Outcomes in Cardiogenic Shock, However STS Mortality and Low EF Predict Survival

Despite marked advances of revascularization, acute myocardial infarction (MI) remains a major cause of mortality. There is a greater than 50% mortality among patients presenting with acute myocardial infarction and cardiogenic shock (AMI-CS). We aim to determine if there are predictors to mortality
The influence on consumer price index change of RMB exchange rate ——An analysis based on co-integration and error correction models

Correct prediction of the relation between RMB exchange rate and price level is important for the People's Bank of China to adapt appropriate exchange rate policy to achieve price stability.Using the Co-integration and Error Correction Models and taking the monthly data from January 2000 to June 2010 as a sample,the essay empirically analyzes the impact of RMB exchange rate on CPI.The results show that: the effective nominal exchange rate appreciation has a certain disinflation impact on domestic price;based on this,it presents that appropriate flexible RMB appreciation policy should be proposed in order to control the current higher price level,but close attention should be paid on the coordination of the fiscal and monetary policy.
A Radiologist's Primer on Bundles and Care Episodes.

Abstract Bundled or episode payments are among the most heavily emphasized approaches to aligning incentives and promoting care coordination, efficiency, and accountability in health care redesign. Bundled or episode payments price a market basket of services for an entire episode of care with both a clearly defined trigger and termination. Because the radiologist is "ancillary" in many bundles, the specialty is often unaware of the phenomenon. This is likely to change rapidly. Radiology is pivotal in high-prevalence, high-impact care areas such as low back pain and stroke that are focuses of widely used system performance metrics. More important, radiology is central to the diagnosis and management of a wide range of important diagnostic issues in areas such as breast cancer, pulmonary nodules, and incidental findings. Three models of bundled care will probably involve radiology intimately in the near future. Pure radiology bundles might be constructed for breast cancer screening and diagnosis, and these could be priced on the basis of guideline-based best-practice frequencies of care events such as recall and biopsy. Clinical bundles, for example low back pain, could be priced on the basis of optimal imaging frequencies. Finally, pricing of imaging studies might include evidence-based frequencies of follow-up imaging for incidental findings.
Catheter-Directed Intraarterial Thrombolysis as Part of a Multidisciplinary Management Protocol of Frostbite Injury

Abstract Purpose To evaluate intraarterial catheter-directed thrombolysis for prediction and prevention of delayed surgical amputation as part of multidisciplinary management of frostbite injury. Materials and Methods A retrospective review was performed of 13 patients (11 men, 2 women; median age, 33.4 y; range, 8–62 y) at risk of tissue loss secondary to frostbite injury and treated with catheter-directed tissue plasminogen activator (t-PA) thrombolysis. Amputation data were assessed on follow-up (mean, 23 mo; range, 9–83 mo). Angiographic findings were classified into complete, partial, and no angiographic response and assessed for association with follow-up amputation rates. Correlation between amputation outcome and duration of cold exposure (mean, 23 h; range, 5–96 h), time between exposure and rewarming therapy (mean, 25.5 h; range, 7–95 h), and time between exposure and t-PA thrombolysis (mean, 32 h; range, 12–96 h) was assessed. Complications were recorded. Results Of 127 digits at risk on baseline angiography that were treated with catheter-directed thrombolysis, complete recovery was seen in 106 (83.4%). Total mean t-PA dose per extremity was 27.5 mg (range, 12–48 mg) over a mean period of 34 hours (range, 12–72 h). Patients with complete angiographic response (8 patients; 79.5% of digits) did not require amputations; 4 of 5 patients (80%) with partial angiographic response (20.5% of digits) underwent amputation ( P = .007). There was no significant correlation between amputation rates and duration of cold exposure ( P = .9), time to rewarming therapy ( P = .88), and time to thrombolysis ( P = .56). Femoral access site bleeding in 2 patients was managed conservatively. One patient underwent surgical exploration for brachial artery hematoma. Conclusions Intraarterial catheter-directed thrombolysis should be included in initial management of frostbite injury, as it may prevent delayed amputations. The degree of angiographic response to thrombolysis can potentially predict amputation outcomes.