cssi/SciSciGPT-SciSciNet huggingface dataset:
The Influence of K-12 Christian Education on Leadership Development

This study was an exploration of the influence of Christian education on leadership development as perceived by people in leadership positions. A small, purposive sample of 10 individuals who are in some position of leadership and who received a Christian elementary and secondary education were interviewed regarding their perceptions of the influence of Christian education on their leadership development. The responses of the participants revealed four themes relevant to the purpose of the study: integration of Christian worldview, influence of teachers and coaches, academic experience, and activities. This study affirmed the importance of educational experience as a life experience, and supported the applicability of Clinton’s Leadership Emergence Theory as a model for evaluating leadership development that occurs in the educational process.
Determination of malachite green and its metabolite, leucomalachite green, in catfish (Ictalurus punctatus) tissue by liquid chromatography with visible detection.

To determine residues of malachite green (MG) and its metabolite, leucomalachite green (LMG), in catfish tissue, analytes are extracted with acetonitrile- buffer and the extract is partitioned into methylene chloride. Final cleanup and isolation are performed on neutral alumina solid-phase extraction (SPE) and propylsulfonic acid cation-exchange SPE columns before analysis by liquid chromatography with visible detection. PbO 2 postcolumn oxidation is performed by isocratic elution with a buffered mobile phase from a cyano column. Recoveries and relative standard deviations (RSDs) from fortified catfish tissues were 72.9% (RSD, 1.92%; 23 ppb), 75.5% (RSD, 6.85%; 11 ppb), and 69.6% (RSD, 6.93%; 5.7 ppb) for MG and 87.4% (RSD, 2.92%; 21 ppb), 88.1% (RSD, 5.94%; 10 ppb), and 82.6% (RSD, 11.5%; 5.3 ppb) for LMG. The method was applied to MG-incurred catfish at depuration times of 0, 2, 4, 8, and 24 h. Average levels of residual MG and LMG in the 24 h depuration catfish tissue were 73.4 and 289 ppb, respectively
Complexity of Yolk Proteins and Their Dynamics in the Sea Star Patiria miniata

Oviparous animals store yolk proteins within the developing oocyte. These proteins are used in gametogenesis and as a nutritional source for embryogenesis. Vitellogenin and the major yolk protein are two of the most important yolk proteins among diverse species of invertebrates and vertebrates. Among the echinoderms, members of the subphyla Echinozoa (sea urchins and sea cucumbers) express the major yolk protein (MYP) but not vitellogenin (Vtg), while an initial report has documented that two Asterozoa (sea stars) express a vitellogenin. Our results show that sea stars contain two vitellogenins, Vtg 1 and Vtg 2, and MYP. In Patiria miniata, these genes are differentially expressed in the somatic and germ cells of the ovary: Vtg 1 is enriched in the somatic cells of the ovary but not in the oocytes, and Vtg 2 accumulates in both oocytes and somatic cells; MYP is not robustly present in either. Remarkably, Vtg 2 and MYP mRNA reappear in larvae; Vtg 2 is detected within cells of the ectoderm, and MYP accumulates in the coelomic pouches, the intestine, and the posterior enterocoel (PE), the site of germ line formation in this animal. Additionally, the Vtg 2 protein is present in oocytes, follicle cells, and developing embryos, but becomes undetectable following gastrulation. These results help elucidate the mechanisms involved in yolk dynamics, and provide molecular information that allows for greater understanding of the evolution of these important gene products.
Arsenic Trioxide (ATO) Is Safe and Effective in Combination with Low-Dose Ara-C (LDAC) for the Treatment of IPSS-2 Myelodysplastic Syndrome (MDS) and Poor-Prognosis Acute Myeloid Leukemia (AML) in Elderly Patients.

Abstract There is no adequate therapy for advanced MDS and elderly AML and treatment outcomes are generally poor. LDAC in elderly AML patients using a variety of dosing schedules results in a CR rate of approximately 20% and possibly improved morbidity and mortality compared to conventional chemotherapy or supportive care. In MDS patients, the CR rates with LDAC are lower, 10–20%, with short duration and no clear benefit over supportive care. On the basis of preclinical data suggesting a possible anti-angiogenic effect of ATO, as well as clinical data showing activity of ATO in MDS, a phase I/II trial of ATO in combination with LDAC was initiated in IPSS-2 MDS and newly-diagnosed, poor-prognosis AML patients. ATO was given at a dose of 0.25 mg/kg for days 1–5 and 8–12. LDAC was dose-escalated from 5 mg/m2 SC BID to the target phase II dose of 10 mg/m2 SC BID for days 1–14 (one treatment cycle). Patients who achieved CR after one treatment cycle were given a second, identical cycle, followed by maintenance treatment of 5 days of LDAC and 2 days of ATO every 28 days. Patients who did not achieve CR after one cycle were given a second cycle beginning between days 21–28, with the addition of ascorbic acid 1g IV within 30 minutes of the ATO infusion. Fifty-seven patients have been enrolled to date, 34 with AML and 23 with MDS. A total of 28 AML and 16 MDS patients are evaluable for response, 38 of whom were treated with the target dose of LDAC. There were no responses in patients treated with less than the target dose. Clinical characteristics of the 28 AML patients include: mean age 75 yrs (range 55–85 yrs; one patient
A Phase I/II Study of Escalating Doses of Thalidomide (Thal) in Conjunction with Bortezomib (Vel) and High Dose Melphalan (Mel) As A Conditioning Regimen for Autologous Peripheral Blood Stem Cell Transplantation (PBSCT) in Patients with Advanced Multiple Myeloma (MM).

Abstract Abstract 3104 Thalidomide is an active agent in the treatment of MM and shows additive and/or synergistic effects when combined with various chemotherapeutics in pre-clinical and clinical models. We conducted a phase I/II study of Thal in combination with Vel and high dose Mel with PBSCT in patients (pts) with either disease progression or less than complete response after a prior PBSCT. Inclusion criteria included a diagnosis of MM and the availability of adequate PBSC. Exclusion criteria were dose-intense therapy within 56 days, uncontrolled infections, uncontrolled CNS metastases, known cardiac amyloid deposition, severe organ dysfunction, Karnofsky score 500/uL 10 days (range, 8–14 days), ANC >1000/uL 10 days (range 9–14 days), and plt >20,000 12 days (range 9–25 days). 28 pts (median age, 56) were enrolled in the phase I and phase II portions of the study. 18 pts were treated for disease progression after prior autologous transplant (median lines of prior therapy =2; range, 1–5); only 22% of pts achieved ≥PR to the most recent therapy prior to PBSCT. 7 pts were enrolled after achieving Our results indicate that high-dose Thal can be safely added up to 1000 mg daily for 5 days to dose-intense Mel and Vel with acceptable toxicities. Confirmation of potential synergistic effects of this combination regimen will require an appropriately designed phase III study. Disclosures: Siegel: Millennium: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Celgene Corp: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. Vesole: Celgene Corp.: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Millennium: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau.
Hot data centers vs. cool peers

Most networked applications use either a largely centralized architecture (e.g. iTunes) or a p2p architecture (e.g. BitTorrent). The popularity of centralized Internet applications such as Search and web portals has fueled the growth of large data centers. Modeling and minimizing the power consumption of large data centers is the hot new research area (pun intended). However, no attention has been paid to the power consumption of p2p systems. This despite the fact that programs like BitTorrent account for up to 95% of Internet traffic today. There are two main reasons why the power consumption of p2p applications has not yet been studied. First, these applications do not consume a large amount of power at a single location. Second, no central entity pays for the power consumed by applications like BitTorrent. Yet, it is undeniable that systems like BitTorrent do consume power, and quite likely, a lot of power. End hosts consume more power as they do more work and routers consume more power as they route additional traffic [3]. Thus one many wonder: is it more energy efficient to download a song from BitTorrent rather than iTunes? To answer such questions, one needs to build models that can predict the power consumption of p2p applications. In this paper, we present an outline of a model that allows us to compare the energy consumed by a p2p system to its centralized counterpart. Note that it is not our aim to advocate one system architecture over another. Many issues such as manageability, reliability and ease of deployment must be taken into account when making high-level architectural decisions. Indeed, it may be entirely infeasible to deploy applications such as web search in a p2p manner. Thus, this model is best viewed as an exercise driven primarily by academic curiosity. And yet, this exercise is not entirely without practical interest. Today energy costs represents a significant component of the capital and operational costs of data centers, and hence it is important to understand whether, and when, alternate system architectures might prove more cost effective. For example, perhaps in controlled environments such as enterprise networks it is reasonable to harness user desktops to take on some of the tasks traditionally assigned to server rooms and data centers? More broadly, models like this help us understand the energy impact of the different design decisions that go into building a large scale system. For example, our model shows that numerous factors such as power consumption of routers, whether the application is communication vs. computation heavy and the efficiency of the protocol design affect the overall power consumption. To the best of our knowledge, this is the first attempt to model the energy consumption of complex networked systems in their entirety. We hope our initial exploration spurs further research on this topic.
The Evolving Role of Diverse Gaseous Transmitters Mediating Heterocellular Communication Within the Vasculature.

Abstract Heterocellular communication between different cell types of the vasculature, both within the blood vessel wall and cells interacting with the blood vessel wall, is absolutely vital and must be tightly regulated. In this Forum, the role of four different gaseous transmitters [nitric oxide [NO], carbon monoxide (CO), hydrogen sulfide (H2S), and superoxide (O2•−)] is examined by four different research groups in detail, with two original articles and two reviews of the literature. In this editorial, we discuss how each of them may contribute their own component to heterocellular signaling in the vasculature. Antioxid. Redox Signal. 26, 881–885.
Digest: For ecologically similar Andean birds, gene flow and plumage uniformity go hand in hand.

The idea that genetic differentiation can proceed despite genetic exchange between divergent lineages is gaining support in evolutionary biology (Nosil 2008). Though theoretically difficult to achieve because interbreeding counteracts population differentiation, divergence with gene flow has shaped the evolutionary histories of diverse organisms including Heliconius butterflies (Martin et al. 2013) and Galapagos finches (de Leon et al. 2010). In some taxa, such as the haplochromine cichlids, hybridization may even have played a creative role, providing the genetic variation necessary to fuel adaptive radiations (Meier et al. 2017). This article is protected by copyright. All rights reserved
Teaching as Applied Behavior Analysis: A Professional Difference

Teaching is a dynamic interaction among four components: the student, the teacher, the curriculum (or what is being taught), and the learned repertoire (how and when to use it). The study and development of teaching as behavior analysis provide in-depth treatment of the dynamic interaction of teaching. Applied behavior analysis is a strategic science. Teaching is a common form of activity, both for species and for many others. As it is so common, its importance and complexity is not appreciated. Yet, the expertise of a teacher, who can function as a strategic scientist of instruction, is vastly different from the level of expertise demonstrated during untutored teaching interactions that occur between parents and children. Learning occurs much more frequently than instances of teaching, which is why inexpert teaching does not result in poor learning outcomes for children, who are raised in privileged settings and have no disabilities.
Discrimination Complaints in the U.S. Federal Government: Reviewing Progress Under the No FEAR Act:

The foundational goal of civil rights legislation is to reduce discrimination, in both the public and private sector. To understand the levels of perceived discrimination in the federal government,...
Optical coherence tomography of lymphatic vessel endothelial hyaluronan receptors in vivo

Optical Coherence Tomography (OCT) imaging of living subjects offers millimeters depth of penetration into tissue while maintaining high spatial resolution. However, because most molecular biomarkers do not produce inherent OCT contrast signals, exogenous contrast agents must be employed to achieve molecular imaging. Here we demonstrate that microbeads (μBs) can be used as effective contrast agents to target cellular biomarkers in lymphatic vessels and can be detected by OCT using a phase variance algorithm. We applied this technique to image the molecular dynamics of lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) in vivo , which showed significant down-regulation during tissue inflammation.
Solution of the Bulgarian Solitaire Conjecture

It's the gaps, not the stacks, that are the key to showing this game can always be won neatly.
Innocence, Perversion, and Heather's Two Mommies

This paper begins by untangling the twisted threads linking homosexuality and childhood in the mind of America, and explaining how contemporary constructions of homosexuality have become entwined with modern conceptions of childhood. The author draws on the literature on the invention of childhood and especially the pioneering work of Jonathan Silin to show how the entrenchment of capitalism and arrival of compulsory schooling have created a hegemonic form of family and produced a child at once innocent and ignorant. The author then probes the construction of “the homosexual” in the late 19th century and uncovers interconnections between this new social typology and representations of childhood. By examining how these linkages are historically embodied in incidents of sex panic, the author argues that the psyches of lesbians and gay men who are in relationship with children (as parents, teachers, coaches . . .) are often suffused with anxiety and self-doubt. Hence a gay movement emerges rife with hyper-traditional representations of children and youth. Contemporary queer representations of childhood are then explored through a focus on children's books designed for the offspring of lesbian and gay parents. The author suggests that contemporary gay advocacy, which attempts to dislodge perversion as the central representation of homosexuality, will be unsuccessful until activists abandon tactics that infantilize children and perpetuate a vision of childhood as vulnerable, innocent, and unknowing.
Source Effect on Near-Field Multi-Beam-Splitting in Fabry-Perot Cavity Antenna System

Fabry-Perot Cavity (FPC)antenna systems can be designed to produce beam-splitting in the near-field as a means of increasing system gain. This paper will describe performance of FPC system when two unidirectional antenna designs are evaluated with frequency selective surface (FSS)design with a cross (i.e. FSS-Cross)to create quad beam-splitting. The cavity-backed slot design has gain that is ~1 dB higher than the patch design.
An empirical study on predicting cloud incidents

Abstract With the increasing rate of adoption and growth of cloud computing services, businesses have been shifting their information technology (IT) infrastructure to the cloud. Although cloud vendors promise high availability and reliability of their cloud services, cloud-related incidents involving outages and service disruptions remain a challenge. Understanding cloud incidents and the ability to predict them would be helpful in deciding how to manage and circumvent future incidents. In this study, we propose a hybrid model that employs machine learning and time series methods to forecast cloud incidents. We evaluate the proposed model using a sample of 2261 incidents collected from two cloud providers namely, Netflix and Hulu. Unique to this study is that our model relies solely on historical data that is independent of the underlying cloud infrastructure. Results suggest that the proposed hybrid model outperforms individual forecasting models: neural network, time series and random forest. Results also reveal important temporal insights from the proposed model and highlights the practical relevance of historical data to forecast and manage cloud incidents.
A National Survey of Internal Medicine Primary Care Residency Program Directors

The United States is facing a primary care physician shortage. Internal medicine (IM) primary care residency programs have expanded substantially in the past several decades, but there is a paucity of literature on their characteristics and graduate outcomes. We aimed to characterize the current US IM primary care residency landscape, assess graduate outcomes, and identify unique programmatic or curricular factors that may be associated with a high proportion of graduates pursuing primary care careers. Cross-sectional study Seventy out of 100 (70%) IM primary care program directors completed the survey. Descriptive analyses of program characteristics, educational curricula, clinical training experiences, and graduate outcomes were performed. Bivariate and multivariate logistic regression analyses were used to determine the association between ≥ 50% of graduates in 2016 and 2017 entering a primary care career and program characteristics, educational curricula, and clinical training experiences. Over half of IM primary care program graduates in 2016 and 2017 pursued a primary care career upon residency graduation. The majority of program, curricular, and clinical training factors assessed were not associated with programs that have a majority of their graduates pursuing a primary care career path. However, programs with a majority of program graduates entering a primary care career were less likely to have X + Y scheduling compared to the other programs. IM primary care residency programs are generally succeeding in their mission in that the majority of graduates are heading into primary care careers.
Biomarkers to diagnose metastatic breast carcinoma to the pancreas: A case report and update.

The patient is a 72-year-old female who presents with new onset jaundice. The patient has a past medical history significant for right-sided estrogen receptor (ER)-positive and left-sided ER-negative breast cancers in 2005 and 2009, respectively, and recent 1-year history of ER-positive right-sided breast cancer with bone and brain metastases. CT scan and endoscopic ultrasound (EUS) revealed a new 2 cm mass in the head of the pancreas, leading to EUS-guided fine-needle aspiration of the lesion. Pathologic workup revealed adenocarcinoma with signet-ring cells, representing either metastatic breast or primary pancreatic cancer. Immunohistochemistry and molecular diagnostic workup identified positive GATA-binding protein 3 (GATA3) immunoreactivity and a mutation in Erb-B2 receptor tyrosine kinase 2 (ERBB2), also known as human epidermal growth factor receptor 2 (HER2). Here, we review the diagnostic markers commonly used to differentiate metastatic breast vs primary pancreatic adenocarcinoma, and discuss the challenges of utilizing GATA3 immunoreactivity and ERBB2 mutations for diagnosis.
Secondary hosts of the Asian citrus psyllid, Diaphorina citri Kuwayama: Survivorship and preference

The Asian citrus psyllid, Diaphorina citri Kuwayama, is the most economically important and difficult to manage citrus pest in Florida due to its role as vector of huanglongbing or citrus greening disease. Spread of the disease is a function of dispersal patterns and thus influenced by availability of suitable hosts. Young leaves of citrus or related plants are required for reproduction, but in their absence, secondary hosts may provide needed resources to enhance survival. Therefore, survivorship on and preference for three abundant weed species was investigated. The suitability of potential secondary host plants Bidens alba (L.), DC, Ludwigia octovalvis (Jacqu.) P. H. Raven, and Eupatorium capillifolium (Lam.) Small was compared to a reproductive host, Murraya paniculata (L.) Jack, in no‐choice tests by assessing survivorship of D. citri adults confined to these plants in cages. Preference was evaluated by choice tests where D. citri adults were released into cages containing all three secondary hosts alone or with M. paniculata. Both B. alba and E. capillifolium increased D. citri survivorship by twofold compared to starvation conditions with only water available. Choice trials revealed no difference in initial selection between true and secondary hosts; however, the true host was favoured over time. This result suggested that hosts were selected initially by sight, and only later by taste and/or smell. While secondary hosts are unable to support reproduction or long‐term survival, these findings establish the ability of D. citri to use secondary hosts that are ubiquitous in Florida citrus groves as temporary reservoirs for food and moisture when ideal host conditions are scarce or absent.
Setting ecological expectations for adaptive management of marine protected areas

Marine Protected Areas (MPAs) are being implemented worldwide, yet there are few cases where managers make specific predictions of the response of previously harvested populations to MPA implementation. Such predictions are needed to evaluate whether MPAs are working as expected, and if not, why. This evaluation is necessary to perform adaptive management, identifying whether and when adjustments to management might be necessary to achieve MPA goals. Using monitoring data and population models, we quantified expected responses of targeted species to MPA implementation and compared them to monitoring data. The model required two factors to explain observed responses in MPAs: (a) pre‐MPA harvest rates, which can vary at local spatial scales, and (b) recruitment variability before and after MPA establishment. Low recruitment years before MPA establishment in our study system drove deviations from expected equilibrium population size distributions and introduced an additional time lag to response detectability. Synthesis and applications. We combined monitoring data and population models to show how (a) harvest rates prior to Marine Protected Area (MPA) implementation, (b) variability in recruitment, and (c) initial population size structure determine whether a response to MPA establishment is detectable. Pre‐MPA harvest rates across MPAs plays a large role in MPA response detectability, demonstrating the importance of measuring this poorly known parameter. While an intuitive expectation is for response detectability to depend on recruitment variability and stochasticity in population trajectories after MPA establishment, we address the overlooked role of recruitment variability before MPA establishment, which alters the size structure at the time of MPA establishment. These factors provide MPA practitioners with reasons whether or not MPAs may lead to responses of targeted species. Our overall approach provides a framework for a critical step of adaptive management.
Countering Botnet of Things using Blockchain-Based Authenticity Framework

The success and widespread use of Internet of Things (IoT) bring remarkable contributions and economic benefits in various fields. However, the increasing number of devices also raises security concerns. The prevalence of Botnet of Things (BoT) has been observed and it has been recently reported that the launched attacks affect multiple domains and have caused unacceptable losses. As majority of IoT devices are manufactured off-shore, ensuring their identity becomes one of the major challenges. Cloned devices, with backdoors for malicious purposes, can provide an undue advantage of the adversary to compromise a system even though proper security measures are in place. In this paper, we propose a novel blockchain-based framework to provide traceability of hardware. A unique identity for every IoT device is ensured using a physically unclonable function (PUF). The blockchain provides the verification of these devices by comparing these unique IDs. HyperLedger is selected to implement the blockchain-based framework, and its performance is being evaluated and analyzed.
Diagnosis of Osteosarcopenia – Imaging

An essential requirement for translating osteosarcopenia research into clinical care is determining the best method for assessing both muscle and bone tissue composition. Several non-invasive imaging modalities exist that differ in terms of accuracy, reliability, cost, and radiation exposure. Magnetic resonance imaging (MRI), computed tomography (CT), dual energy X-ray absorptiometry (DXA), and ultrasound all have variable importance in assessing sarcopenia and osteoporosis, and may provide useful information for clinical decision making aimed at reducing falls, injuries and fractures. Recent advances to these technologies focus on measures that describe tissue ‘quality’, an important improvement beyond measurement of quantity, to better explain the gap in knowledge connecting muscle and bone with function, fracture, and mortality. Aligned with the growing interest in osteosarcopenia, this chapter explores the clinical applications and limitations of various imaging techniques available for the assessment of muscle and bone in the diagnosis of osteosarcopenia.
Future Research Directions in Young Children’s Early Learning of Mathematics

Let us define the modern era of schooling as dating from the industrial revolution. Mass education became a practical necessity at about that time in order that a salisfactorily-trained work force would become available to meet the demands of the rapidly changing commercial world. No longer could the traditional apprenticeship system, based on a one-to-one relationship between artisan and novice, produce sufficient numbers of semiskilled workers; nor were newly-needed skills able to be acquired under the old system. Workers were now needed who were to some degree dogmatized and socialized into acceptance of new roles whose facets were dependent on an entirely new conception of industry. The modern school was thus begun to teach rudiments of reading, writing, and numbering to the masses in order that many of their number would be employable in the factories that were rapidly emerging. As the associated expansion of the marketplace occurred, the need for clerks (and secretaries) grew very rapidly; these classes of worker needed bookkeeping (and secretarial skills) to take on the work of calculating accurately and transposing the results in a good hand into the increasingly-important ledgers of companies (and to draft business and legal correspondence). Here we see the sources of school curricula that emphasized quick, accurate acquisition of number facts (and legible handwriting) in the elementary school; have those emphases been reduced in schools to match the rate of invention of machinery to carry out the tasks of calculating, bookkeeping and writing?
Cultural Competence or Deficit-Based View? A Qualitative Approach to Understanding Middle School Students' Experience with Culturally Framed Engineering.

Recent policies have given momentum to the science, technology, engineering, and mathematics (STEM) education in the USA and throughout the world. This has resulted in rapid growth in engineering and STEM curricula, many of which incorporate global contexts to frame student experiences; however, little research has been done on the effects of this contextualization. Thus, it is critical to explore the impact of these curricula on student learning and the development of STEM identities, especially those who have historically been marginalized in STEM fields. The purposes of this study are to critically examine how STEM curriculum helps shape students’ perceptions of the underlying cultural context and suggest ways that anti-oppressive education theory can be applied in middle school physical science classrooms. This study draws on classroom observational data and the curriculum text itself to understand how students perceive culture that they do not identify with. We found that the curriculum provides very limited perspectives of the non-dominant culture in which the learning was situated. Our results also indicate three emerging themes showing students to be demonstrating an elitist viewpoint, having a narrow view of another culture, or being indifferent toward the embedded cultural context in the lessons. As a class, deficit-based views of the people and places presented in the lesson were created rather than the desired culturally competent views. These negative perceptions were imprinted and solidified through limited portrayal of the embedded culture in the curriculum. This work highlights the importance of curriculum context in students’ learning. Beliefs about the people and places are created through global context presented in the curriculum. Portrayal of these people and places was not representative of the culture; thus, resulting in limited perceptions of the situated contexts. It is crucial that the teachers critically evaluate the curriculum prior to its implementation to make sure Others are represented appropriately by drawing upon the anti-oppressive education theory. Lastly, we also advocate for the incorporation of global culture in STEM curriculum by having students learn beyond what the written curriculum offers.
A Case Report of Isopropanol Ingestion During the SARS-CoV-2 Pandemic.

Introduction Patients with substance use disorder may be particularly vulnerable to withdrawal-related complications during the SARS-CoV-2 (COVID-19) pandemic. Limited availability of alcohol and other substances coupled with decreased accessibility to substance use treatment poses a substantial risk to this population. Isopropanol, the active ingredient in rubbing alcohol, is widely available; thus, it may be used in times of scarcity. Case report We present a case of intentional isopropanol ingestion used as an ethanol surrogate within the setting of the COVID-19 pandemic. Conclusions Toxic alcohol ingestions are imperative considerations on the differential for the intoxicated patient particularly during resource-limited times.
An advancement in the study of marketing partnership longevity: analysing sport sponsorship survival

Naming rights agreements are some of the most high profile, and costly, sponsorships in the world. Yet, while growth in investments in these multimillion-dollar partnerships has recently outpaced t...
Winds from seattle: database research directions

The database research community has been notably successful in impacting the industry and academia since the invention of the relational model. Examples of innovation in the last decade include columnar storage for data analytic platforms, cloud data services, HTAP systems, and a new generation of data wrangling systems. Despite this success, critical self-assessment by the community and identifying key opportunities for the future is essential if we are to continue the tradition of impactful research. In the Fall of 2018, following a long tradition that dates back to 1988 [4], and five years after the last such meeting [1], a group of approximately thirty database researchers gathered at the University of Washington, Seattle for two days to discuss the opportunities we have as a community for impactful research. A report from that meeting is now available [2]. The discussions in the Seattle meeting focused not just on technical challenges and opportunities but also on topics related to how we organize ourselves as a community. This VLDB panel follows on from a previous discussion at SIGMOD 2020 [3], to provide a forum for the broader database community to review and debate the findings from the Seattle Report on Database Research [2] as well as to identify other challenges, and opportunities that need to be taken into account.
A Kaleidoscopic Future: The State and Assemblages in Global Affairs

The future of Global Affairs will revolve around the state. The erstwhile commitment to multilateralism that was a key feature of the world order since 1945 has faded, only to be replaced with a more self-interested view. The arrangements that states will find themselves in will not be fixed, but transitory. Stable alliances and global agreements will be replaced by temporary hook-ups. This does not bode well for our ability to tackle global challenges.
Postoperative opioid use for patients with chronic pelvic pain undergoing robotic surgery for resection of endometriosis

We aimed to identify the amount of opioids used in the postoperative setting for patients with a history of chronic pelvic pain undergoing robotic surgical excision of endometriosis and compare this to patients undergoing benign robotic gynecologic surgery for other indications. We conducted a retrospective cohort study in an urban academic university hospital from January 2019 to March 2020. Data regarding opioid use was collected via a patient-reported survey that was given at the 3 weeks follow-up visit. Data regarding opioid use was compared to patients undergoing robotic surgery for other benign gynecologic indications. Our study included 158 patients, 119 undergoing surgery for endometriosis and 39 patients undergoing robotic surgery for other benign gynecologic indications. Patients undergoing surgery for endometriosis used on average 105.9 morphine milligram equivalents (MME), equivalent to 14 tabs of oxycodone 5 mg. There was no statistically significant difference in the amount of opioids used postoperatively based on stage of endometriosis or need for hysterectomy. Patients undergoing surgery for other benign indications used on average 49.4 MME, equivalent to 6 tabs of oxycodone 5 mg. The difference in amount of opioids used between patients with and without endometriosis was statistically significant. In conclusion, patients undergoing robotic surgery for endometriosis used over two times as many opioids postoperatively as patients without endometriosis and have a higher perceived postoperative pain. Providers should be aware of this difference in order to provide better pain control for this patient population.
Swine models for translational oncological research: an evolving landscape and regulatory considerations

Swine biomedical models have been gaining in popularity over the last decade, particularly for applications in oncology research. Swine models for cancer research include pigs that have severe combined immunodeficiency for xenotransplantation studies, genetically modified swine models which are capable of developing tumors in vivo, as well as normal immunocompetent pigs. In recent years, there has been a low success rate for the approval of new oncological therapeutics in clinical trials. The two leading reasons for these failures are either due to toxicity and safety issues or lack of efficacy. As all therapeutics must be tested within animal models prior to clinical testing, there are opportunities to expand the ability to assess efficacy and toxicity profiles within the preclinical testing phases of new therapeutics. Most preclinical in vivo testing is performed in mice, canines, and non-human primates. However, swine models are an alternative large animal model for cancer research with similarity to human size, genetics, and physiology. Additionally, tumorigenesis pathways are similar between human and pigs in that similar driver mutations are required for transformation. Due to their larger size, the development of orthotopic tumors is easier than in smaller rodent models; additionally, porcine models can be harnessed for testing of new interventional devices and radiological/surgical approaches as well. Taken together, swine are a feasible option for preclinical therapeutic and device testing. The goals of this resource are to provide a broad overview on regulatory processes required for new therapeutics and devices for use in the clinic, cross-species differences in oncological therapeutic responses, as well as to provide an overview of swine oncology models that have been developed that could be used for preclinical testing to fulfill regulatory requirements.
The Election of Israel: The Idea of the Chosen People

Preface List of abbreviations Introduction 1. Spinoza and his challenge 2. Hermann Cohen's concept of election 3. Franz Rosenzweig's return to the doctrine 4. The retrieval of the biblical doctrine 5. The rabbinic development of the doctrine 6. Two medieval views of election Conclusion Appendices Bibliography Index.
A Dream Comes True: The Wright Brothers and Their Predecessors

In the wind-swept sand dunes of Kill Devil Hills, about four miles south of Kitty Hawk, North Carolina, on the Atlantic coast, an old dream of man became a reality. By the toss of a coin on December 14, 1903, Wilbur Wright (1867–1912) won the first turn at piloting the powered airplane he had built with his brother Orville (1871–1948). The weather was beautiful, but the wind seemed insufficient for the Wright Flyer I to start from the 9° slope of the dune. The two skids of the aircraft—no undercarriage with wheels existed at the time—were set on a yoke running on a single track. Five men from the local lifesaving station helped with this work. The engine was warmed up while the flying machine was restrained. When all was ready, the men holding it let go, and, after a short run of 35 to 40 feet on the track, the airplane lifted off the yoke into the air. Despite this initial success, the Flyer’s nose turned up too quickly, leading to a stall. A rough landing in the sand broke one of the skids and damaged a control surface, ending further attempts at flight for the day.
Microtechnique for Determining the Specific Activity of Radioactive Intracellular Leucine and Applications to in Vivo Studies of Protein Synthesis

Abstract A microtechnique has been developed for the determination of specific activities of radioactive leucine in the nanogram range, with an accuracy of at least 7%. The technique depends on the coupling of [3H]leucine to [14C]2,4-dinitrofluorobenzene. By use of inulin in the incubation medium, a correction can be made for extracellular leucine contaminating the tissue, and thus the specific activity of the intracellular leucine pool can be estimated. The technique has been applied to determining rates of protein synthesis in a protein-secreting gland, the galea of the silkmoth, Antheraea polyphemus, after progressive exposure to actinomycin D. Actinomycin D is shown to "superinduce" incorporation of [3H]leucine in the differentiation-specific product of the galea, the zymogen of cocoonase. However, superinduction is illusory; when changes in specific activity of the intracellular pool are taken into account, no actinomycin effect on zymogen synthesis is apparent.
Gender and International Marriage Migration

In the last two decades, the growth of intra-regional marriage migration in Asia has stimulated scholarly interest in destination countries. Marriage migration led to social, demographic, and cultural transformations of current and future generations in these countries, and raised new issues in relation to race, ethnicity, gender, class, and nationality. Recent scholarly work on international marriage migration has moved beyond the so-called mail-order bride discourse and has critically examined various aspects of the experiences of women marriage migrants in affinal families, communities, and societies. Influenced by the postcolonial feminist perspective, a great deal of the ethnographic and qualitative research on international marriage migration focuses on women’s agency, the patriarchal and heteronormative underpinnings of marriage, and incongruous gender relations, as well as the dynamics between local transformations and the global political economy.
Liquid Crystal Display (LCD)

A liquid crystal display (LCD) is a flat panel electronic visual display that uses a two-dimensional array of liquid crystal (LC) cells, each of which can be electrically controlled to modulate the transmission of light for the display of digital images. Among all the electronic visual displays in the current world, LCD is taking the dominant position owing to its flat panel, light weight, low driving voltage, low power consumption, high resolution, large viewing angle, high color quality, and availability in a large range of screen size. In this chapter, we describe the basic device structure including various components, principle of operation, properties of LC materials, and various LCD modes of operation and their applications. We also point out some of the fundamental limitations of the LCDs. Keywords: liquid crystal display (LCD); contrast ratio; viewing angle; compensator; thin film transistor (TFT); active matrix (AM); response time; vertical alignment (VA); in-plane switching (IPS); twisted nematic (TN)
Metal-Centered Star Block Copolymers: Amphiphilic Iron Tris(bipyridine)-Centered Polyoxazolines and Their Chemical Fragmentation to Bipyridine-Centered BAB Triblock Copolymers

Amphiphilic metal-centered six-arm star block copolymers were prepared by the sequential addition of two different oxazoline monomers to the hexafunctional metalloinitiator, [Fe(4,4‘-bis(chlorometh...
Growth Response of Halophila engelmanni Aschers. to Sulfide, Copper, and Organic Nitrogen in Marine Sediments.

Growth response of the seagrass Halophila engelmanni Aschers. was studied using defined culture techniques. When added to the rhizosphere, nutrient-seawater medium supported vigorous plant growth, if substantial Cu (10 times that in modified Hoagland solution) plus organic N were present. H2S up to 0.2 millimolar in the sediment was not inhibitory. A requirement for exogenous organic N, especially urea, is postulated for vigorous growth of Halophila.
Adaptive RS Code for Message Delivery Over Encrypted Military Wireless Networks

This paper presents a technique that uses a family of Reed-Solomon (RS) code for the assured delivery of short, high-importance messages over IP-based military wireless networks with encryption. Encryption devices drop malformed packets upon receipt, assuming that they may be the result of enemy attacks. To the session layer on the plain-text side, encryption devices introduce packet loss. The presented technique attempts to ensure the delivery of short, high-importance messages while optimizing for Speed Of Service (SOS) requirements and network throughput (i.e., the minimum number of redundancy packets is added to assure delivery within the SOS requirements). As a result, high-importance messages such as a call for fire are delivered in time over the encrypted wireless network, even if the network suffers from attacks or fading.
Components of conspecific host discrimination behavior in the butterfly Battus philenor.

The hypothesis that pipevine swallowtail butterflies (Battus philenor) dis- criminate among Aristolochia reticulate host plants according to their suitability forjuvenile survival was investigated under field and enclosure conditions. Butterflies discriminated among host plants differing in leaf quality both before and after landing. Over 3 yr of field observations, the host plants on which females landed and oviposited were smaller, pos- sessed longer buds, and bore a higher percentage of high-quality leaves than host plants on which females landed but left without depositing eggs. Similarly, the host plants on which females landed in those years were not a random sample of the host plants available in the habitat. Plants on which the butterflies alighted bore a higher percentage of high- quality leaves, a lower percentage of low-quality leaves, and longer buds than their nearest neighbors that were not landed upon. These characteristics were associated with differences in expected larval growth and survival. Field and enclosure experiments in which variation in certain plant characters was manipulated independently of variation in other plant characters generally confirmed these results. Enclosure studies suggested strongly that fe- males learned to land on particular host types according to the responses those plants had elicited after previous alightings. The implications of that finding for models of the evolution of pre-alighting and post-alighting components of discrimination behavior are discussed.
DON'T JUST TELL ME WHAT YOUR COMPUTER TOLD YOU

ABSTRACT Computer assignments and writing assignments have many common goals. Integrating the two techniques enhances the computer assignments and is very effective in engaging students and leading them toward independent and creative thinking.
Stable isotopes differentiate bottlenose dolphins off west-central Florida

Distinguishing discrete population units among continuously distributed coastal small cetaceans is challenging and crucial to conservation. We evaluated the utility of stable isotopes in assessing group membership in bottlenose dolphins (Tursiops truncatur) off west-central Florida by analyzing carbon, nitrogen, and sulfur isotope values (δ 13 C, δ 15 N, and δ 34 S) of tooth collagen from stranded dolphins. Individuals derived from three putative general population units: Sarasota Bay (SB), nearshore Gulf of Mexico (GULF), and offshore waters (OFF). Animals of known history (SB) served to ground truth the approach against animals of unknown history from the Gulf of Mexico (GULF, OFF). Dolphin groups differed significantly for each isotope. Average δ 13 C values from SB dolphins (-10.6‰) utilizing sea grass ecosystems differed from those of GULF (-11.9‰) and OFF (-11.9‰). Average δ 15 N values of GULF (12.7‰) and OFF (13.2‰) were higher than those of SB dolphins (11.9‰), consistent with differences in prey trophic levels. δ 34 S values showed definitive differences among SB (7.1‰), GULF (11.3‰), and OFF (16.5‰) dolphins. This is the first application of isotopes to population assignment of bottlenose dolphins in the Gulf of Mexico and results suggest that isotopes may provide a powerful tool in the conservation of small cetaceans.
Hydrogen bonding and equilibrium isotope enrichment in histidine-containing proteins

We have measured deuterium/hydrogen fractionation in three histidine-containing proteins, ecHPr, ecHPr mutant S31A, and bsHPr, and in random coil peptides using NMR and mass spectrometry. The amide protons of unstructured peptides exhibit equilibrium enrichment for deuterium, in agreement with previous studies. Enrichment for both protium and deuterium was observed in both HPrs, with fractionation factors ranging from 0.63 to 1.41. Enrichment for protium was seen in alpha-helical secondary structure. 'Strong' HBs previously identified by mutagenesis and thermodynamic measurements are significantly enriched for protium. Sites of protium enrichment are conserved in a structural context across species lines, though ecHPr and bsHPr share only 30% sequence identity, suggesting that strong HBs are conserved and may play an important role in stabilizing the folded state.