Abstract A60: Para nuestra comunidad: A Spanish video promoting clinical trials, biospecimen studies, and research participation for advancing cancer research and quality care

Background: The recruitment of ethnic minorities, particularly Latinos, into clinical trials (CT) and biospecimen studies (BB) is a formidable challenge. Latinos equal 17% of the US population and Cancer is their leading cause of death. Increasing their inclusion in biomedical research contributes to advancing public health and medical research and practice. Videos have been used widely in health education with Latinos; yet no adequate Spanish language videos promoting CT and BB exist. Objective: Produce and test a culturally and linguistically tailored 3-minute Spanish video to promote Latino participation in CT and BB. The specific aims are to: 1) educate on the importance of CT and BB studies; and 2) promote acceptability and willingness to participate in CT and BB studies. Participants: Preliminary evaluation was conducted with Latino advocates, survivors and/or family members. Participants viewed the video then completed a short evaluation measuring knowledge, acceptability and willingness to participate in CT and BB. Research Methods: The Theory of Reasoned Action/Planned Behavior was used to guide the video production. The video script was informed by our earlier research studies, community assessments, and focus groups. The literature and our findings underscore that Latinos are more willing to participate in CT and BB if there is perceived familial benefit with individual benefit weighing less impact on research participation decision making. The video was finalized based on consensus input from community partners and City of Hope clinicians who were fluent in Spanish and serve the Latino community. Results: Preliminary findings show that after viewing the video, 100% and 80% of respondents were likely to encourage CT and BB participation with their family and community, respectively; and 70% were more willing to participate in a research study after viewing the video. Qualitative results highlighted that the video was “educational, easy to understand, and informative.” One respondent wrote that using real people with the experience (of CT, BB and research participation) made the video more real and personal. Another respondent expressed interested in using the video for their community-based programs. Conclusions: Preliminary evaluation show that the video increased knowledge, acceptability and willingness to participate in CT and BB among Latinos. Therefore, this culturally and linguistically appropriate video has potential as an effective strategy for engaging Latinos in CT and BB. Future plans include continued evaluation of the video and broad dissemination via BMaP, NCI National Outreach Network, and various local and national community-based organizations. Citation Format: Mayra Serrano, Sophia Yeung, Kimlin Ashing. Para nuestra comunidad: A Spanish video promoting clinical trials, biospecimen studies, and research participation for advancing cancer research and quality care. [abstract]. In: Proceedings of the Sixth AACR Conference: The Science of Cancer Health Disparities; Dec 6–9, 2013; Atlanta, GA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2014;23(11 Suppl):Abstract nr A60. doi:10.1158/1538-7755.DISP13-A60