Identifying content gaps in health status measures for intermittent claudication using the International Classification of Functioning, Disability and Health.

Abstract Objective The Walking Impairment Questionnaire (WIQ) and Intermittent Claudication Questionnaire (ICQ) are commonly used patient-reported functional outcome measures for intermittent claudication, but their functional representation has not been characterized. The World Health Organization's International Classification of Functioning, Disability and Health (ICF) framework comprehensively describes health-related function and has been used to evaluate health status and quality of life (QOL) measures. We applied a content analysis technique commonly used in functional rehabilitation research to evaluate ICF domains represented by WIQ and ICQ to characterize their health status and functional representation. Methods The overall perspective of each question was assigned as health status–function, health status–disability, Environment–facilitator, Environment–barrier, or QOL. All meaningful concepts in each question were identified and linked to the most appropriate and precise ICF code from the hierarchy of component, chapter, or category using the validated technique. A 20% random sample of questions was secondarily coded with disagreements resolved by discussion. Results Codability was agreed upon for 87% of questions; agreement was 100% on component and chapter and 88% on category. WIQ contains 18 concepts among 14 questions (1.3 concepts per question); all questions are from the health status–disability perspective. All WIQ concepts are from the "Activities/Participation-d" ICF component, "Mobility-d4" chapter. "Walking long distances" (d4501, >1 km) is omitted. ICQ contains 37 codable concepts among 16 questions (2.3 concepts per question). Thirteen questions are from health status-disability perspective, three from QOL. Sox of the nine chapters of the "Activities/Participation-d" ICF component are represented by 20 of 37 concepts; 11 of 20 in the "Mobility-d4" chapter. The other "Activities/Participation-d" chapters and categories in ICQ are "Learning/applying knowledge" ("thinking-d163"), "General tasks/demands" ("carrying out daily routine-d230"), "Domestic life" ("shopping-d6200," "doing housework-d640"), "Major life areas" ("Maintaining a job-d8451"), and "Community life" ("socializing-d9205," "hobbies-d9204"). "Body Functions-b" ICF component is represented 11 times, covering pain, numbness, emotion, mood, and cardiovascular functions. "Body Structures-s" is represented three times as lower extremity. Neither WIQ nor ICQ specifically addresses "Walking on different surfaces," (64,502) "Walking around obstacles" (d4503), or "Moving around using equipment" (d465), which includes assistive devices. Walking on an incline is not addressed in WIQ, ICQ, or the ICF. Conclusions Applying this ICF-based content assessment methodology to patient-reported vascular disease outcome measures is feasible, representing a novel method of assessing such instruments. WIQ's scope is limited; it does not address functional capacity and covers only health status pertaining to walking disability. The ICQ is more inclusive, but concept density may obscure meaning. Neither instrument is functionally comprehensive and both have significant omissions that should be considered for inclusion.