cssi/SciSciGPT-SciSciNet huggingface dataset:
The “Mini-Mental State” Examination in the Syndrome of Self-Induced Water Intoxication and Schizophrenic Disorders (SIWIS): A Pilot Study:

A quantitative assessment of cognitive state (Folstein's “mini-mental state” scores) was correlated with serum sodium concentration in four patients with the syndrome of self-induced water intoxica...
Prevention of Pressure Ulcers Among People With Spinal Cord Injury: A Systematic Review

Abstract Objectives To evaluate the literature on the effectiveness of bed and wheelchair positioning and repositioning in the prevention of pressure ulcers (PUs) in both the spinal cord injury (SCI) and non-SCI populations. Design Systematic review. Methods PubMed, CINAHL, PsycINFO, and EMBASE were queried with the subject heading terms "pressure sore," "pressure ulcer," "position or turn in bed, wheelchair," "pressure relief," and "pressure release." All study design types that assessed the effectiveness of bed and wheelchair positioning and pressure relief maneuvers in any patient group and in any setting were sought. Three independent reviewers extracted and summarized details of eligible trials using a standardized method. Two independent reviewers assessed the methodological quality of each trial using the American Academy of Neurology guidelines. When reviewers were not able to reach consensus, a third independent reviewer served as tiebreaker. Results We identified 2820 publications, of which 49 met inclusion criteria. Of these publications, the subject population was 2834 (923 persons with SCI, 717 persons without SCI, and 1194 healthy control subjects). Among studies examining pressure related to position or repositioning in bed or sitting, procedures for measuring skin pressure and metabolism were highly variable by anatomic location, measurement technique, outcome measure, study site, participant characteristics, and description of position/turning for bed and seated interventions. Numerous factors can influence tissue interface pressures, and no prospective studies had been performed to determine a causal relationship between interface pressure and skin breakdown. Several studies suggest that skin response to pressure differs between subjects with and without SCI. Conflicting results and insufficient evidence for optimal bed and seated positioning and turning and pressure relief maneuvers to prevent PUs in both SCI and non-SCI populations were limiting factors. Conclusions Although there is no clear optimal positioning or turning frequency in bed, the evidence suggests avoiding the 90° lateral position because of high pressures and PU risk over the trochanters. During sitting, pressures are linearly redistributed from the sitting area during recline and tilt; however, reclining carries with it an increased risk of shear forces on this skin. The evidence does not support conclusive guidelines on positioning or repositioning techniques for PU prevention in bed or during sitting. We conclude that PU risk is highly individualized, with the SCI population at a higher risk, which demands flexible PU prevention strategies for bed/seated positioning and pressure relief maneuvers. Education has and will remain our most powerful ally to thwart this pervasive public health problem.
Influenza Virus–induced Dendritic Cell Maturation Is Associated with the Induction of Strong T Cell Immunity to a Coadministered, Normally Nonimmunogenic Protein

We evaluated the proposal that during microbial infection, dendritic cells (DCs) undergo maturation and present a mixture of peptides derived from the microbe as well as harmless environmental antigens. Mice were exposed to an aerosol of endotoxin free ovalbumin (OVA) in the absence or presence of influenza virus. In its absence, OVA failed to induce B and T cell responses and even tolerized, but with influenza, OVA-specific antibodies and CD8+ cytolytic T lymphocytes developed. With or without infection, OVA was presented selectively in the draining mediastinal lymph nodes, as assessed by the comparable proliferation of infused, CD8+ and CD4+, TCR transgenic T cells. In the absence of influenza, these OVA-specific T cells produced little IL-2, IL-4, IL-10, and IFN-γ, but with infection, both CD4+ and CD8+ T cells made high levels of IL-2 and IFN-γ. The OVA plus influenza-treated mice also showed accelerated recovery to a challenge with recombinant vaccinia OVA virus. CD11c+ DCs from the mediastinal lymph nodes of infected mice selectively stimulated both OVA- and influenza-specific T cells and underwent maturation, with higher levels of MHC class II, CD80, and CD86 molecules. The relatively slow (2–3 d) kinetics of maturation correlated closely to the time at which OVA inhalation elicited specific antibodies. Therefore respiratory infection can induce DC maturation and simultaneously B and T cell immunity to an innocuous antigen inhaled concurrently.
CATEGORFZING AND PREDICTING ERRORS IN SOFTWARE PROGRAMS

The lOAl Operational Program was formally This paper investigates the application of empirical software released to Software Configuration Management in Feberror dita-as applied to failure trend analysis and residual error ruary 1977. Since release, it has undergone four prediction. Ths paper: 1) identifies the types and frequency of reassemblies resulting from errors identified in the software errors experienced; 2) makes a comparison between errors experienced in two designs; 3) details a model for predict- program. During the reporting period a of ing the Mean Time to Failure (MTTF) of software; and 4) recom- Investigation Requests (IRs) reporting software problems mends corrective action as to how to reduce and/or limit errors were accumulated; 107 of these IRs resulted in software in future development efforts. changes. The data, when analyzed, shows a steady but gradual decrease in the number of software errors as the program enters the maintenance phase of its life cycle. The data points to the fact that there is a significant difference in the number of program errors experienced in the two designs studied. Of those errors identified, Raytheon Design Changes (RDCs) and Software Design Errors (SDEs) accounted for the largest percentage of the experienced errors; i.e., design changes were the single most critical factor that contributed to software errors. By means of error estimation, a total of 16 residual errors is estimated in the operational program. The data further identified that the majority of those errors are logical software design errors. Also discussed is a simplified approach to determining, within specified confidence levels, the MTTF of the program. The 10A2 Program was released to Configuration Management in May 1977. The PV portion of the program was added in J uly 1977. This activity doubled the program size and necessitated redefining its baseline. Subsequent reassemblies were needed to correct software e rrors. A total of three updates to t he original released baselined program has been made to date. During the reporting period a total of 32 IRs were accumulated, 28 result in design changes to the 10A2 Program.
Effects of justification and a mechanical aid on judgment performance

Abstract This study examines the effect on judgment performance of an explicit justification requirement and of having available the recommendations of a mechanical judgment aid. The subjects are professional auditors, and the task is the classification of industrial bond issues into rating categories that reflect differential levels of financial quality. It is found that both the justification requirement and the availability of the mechanical aid are associated with significantly greater judgment accuracy which can be traced to significantly greater consistency. Both factors are also associated with significantly greater consensus, or agreement among judges, which can be important when accuracy cannot be assessed. Several directions for further research on justification and judgment aiding in applied contexts are discussed.
Completely rank-nonincreasing linear maps on spaces of operators

We discuss some results and conjectures concerning rank-nonincreasing, rank-preserving, completely rank-preserving and completely rank-nonincreasing linear maps on spaces of operators. We show that the main conjectures are equivalent to a statement about closures of joint similarity orbits of k-tuples of matrices.
Classification of Cylindrical Targets Buried in Seafloor Sediments

This paper presents the development and evaluation of a time-frequency processing technique for detection and classification of buried cylindrical targets from chirp-based parametric sonar data. The software is designed to discriminate between cylindrical targets - such as cables - of different diameters, which need to be identified as different from other strong reflectors or point targets. The method is evaluated on synthetic data generated with an acoustic scattering model for elastic cylinders for seven different diameters. The model generates characteristic responses of targets acquired by a parametric sonar system. The signal at the sonar receiver hydrophones is first windowed to reduce the data to the region of interest (buried target return). This return is then transformed using joint time-frequency transforms (we use the Wigner and Choi-Williams distributions) to produce a 2D image of the return. Dimensionality reduction and feature extraction are performed by singular value decomposition of this time-frequency image. Linear, quadratic, and Mahalanobis discriminant functions are then applied to the most significant singular values to produce the final classification. The study is carried out for various scenarios of free field response of targets as well as for responses from targets buried in sediment.
Ring-opening metathesis polymerization (ROMP) of norbornenyl-functionalized fatty alcohols

Novel biorenewable-based thermosets have been successfully synthesized by the ring-opening metathesis polymerization (ROMP) of norbornenyl-functionalized fatty alcohols derived from soybean oil (NMSA), Dilulin (NMDA), ML189 (NMMA) and castor oil (NMCA). The effects of the monomer structure on the polymerization process, and the thermal and mechanical properties of the resulting thermosets have been extensively investigated. The number of ROMP-reactive rings appended to the fatty acid chain and the viscosity play an important role in controlling the initiation and propagation processes of the polymerization and the final properties of the thermosets obtained. The thermosets have been characterized by Soxhlet extraction, DMA, TGA, and tensile tests. It has been found that polyNMDA and polyNMMA have best thermo-mechanical properties. Compared with polyNMSA, the polyNMDA and polyNMMA thermosets exhibit lower soluble fractions, and higher thermal stabilities and mechanical properties, because of more effective crosslinking; whereas, polyNMCA exhibits a higher soluble fraction, and lower thermal stability, resulting from incomplete polymerization of the more viscous NMCA monomer.
A specific human lysophospholipase: cDNA cloning, tissue distribution and kinetic characterization.

Abstract Lysophospholipases are critical enzymes that act on biological membranes to regulate the multifunctional lysophospholipids; increased levels of lysophospholipids are associated with a host of diseases. Herein we report the cDNA cloning of a human brain 25 kDa lysophospholipid-specific lysophospholipase (hLysoPLA). The enzyme (at both mRNA and protein levels) is widely distributed in tissues, but with quite different abundances. The hLysoPLA hydrolyzes lysophosphatidylcholine in both monomeric and micellar forms, and exhibits apparent cooperativity and surface dilution kinetics, but not interfacial activation. Detailed kinetic analysis indicates that the hLysoPLA binds first to the micellar surface and then to the substrate presented on the surface. The kinetic parameters associated with this surface dilution kinetic model are reported, and it is concluded that hLysoPLA has a single substrate binding site and a surface recognition site. The apparent cooperativity observed is likely due to the change of substrate presentation. In contrast to many non-specific lipolytic enzymes that exhibit lysophospholipase activity, hLysoPLA hydrolyzes only lysophospholipids and has no other significant enzymatic activity. Of special interest, hLysoPLA does not act on plasmenylcholine. Of the several inhibitors tested, only methyl arachidonyl fluorophosphonate (MAFP) potently and irreversibly inhibits the enzymatic activity. The inhibition by MAFP is consistent with the catalytic mechanism proposed for the enzyme – a serine hydrolase with a catalytic triad composed of Ser-119, Asp-174 and His-208.
New, Guaranteed Positive Time Update for the Two-Step Optimal Estimator

A new time update for the two-step optimal e lter is presented. This time update eliminates the occurrence of low eigenvaluesin thee rst-step covariance for certain systems. This event left the e rst-step covariance singular (or negative dee nite ) and often resulted in an unstable implementation. The new time update is guaranteed positive dee nite and signie cantly improves the performance of the two-step estimator on all systems. The two-step e lter is an alternative to the standard recursive estimators that are applied to nonlinear measurement problems, such as the extended and iterated extended Kalman e lters. It improves the estimate error by splitting the cost function minimization into two steps (a linear e rst step and a nonlinear second step ) by dee ning a set of e rst-step states that are nonlinear combinations of the desired states. A linear approximation is made in the time update of the e rst-step states rather than in the measurement update as in conventional methods.
Response diversity and dual response mechanism of organic field-effect transistors with dinitrotoluene vapor

We employ an assortment of n- and p-channel organic semiconductors to fabricate organic field-effect transistors (OFETs) that respond in different ways to dinitrotoluene (DNT) vapor. Different responses are obtained from devices with various semiconductor materials and receptor functionality. Differences are noted in the magnitude and direction of current changes, and also the device parameters (mobility and threshold voltage) affected. The pattern of responses includes sufficient diversity to set it apart from other vapors that might give similar responses to some OFETs in the set, but not all of them. This gives rise to the possibility of distinguishing DNT from other vapors in a manner that could be further developed using mechanistic principles elucidated in this work.
MFM observation of localized demagnetization in magnetic recordings

The micromagnetic details of magnetization reversal were studied using Magnetic Force Microscopy (MFM). We developed a correlation technique using MFM images to measure changes in magnetization. These correlations are related to the changes in magnetization, as measured in a Vibrating Sample Magnetometer (VSM). This technique was used to examine the onset of demagnetization near a transition.
DEVELOPMENT OF TWO-DIMENSIONAL TURBULENT WAKES IN A CURVED CHANNEL AT POSITIVE STREAMWISE PRESSURE GRADIENT

The development of turbomachinery wake flows are greatly influenced by streamline curvature and streamwist pressure gradient. This papa is a part of a comprehensive experimental and theoretical study on the development of the steady and the periodic unsteady turbulent wakes in curved channels at different streamwise pressure gradients. The experimental investigation of the two-dimensional wake behind a stationary circular cylinder in a curved channel at positive streamwise pressure gradient is reported in this paper. Measurements of mean velocity and Reynolds stress components are carried out using a X-hot-film probe. The measured quantities obtained in probe coordinates are transformed to a curvilinear coordinate system along the wake center line and are presented in similarity coordinates. The results indicates strong asymmetry in velocity and Reynolds stress components. The Reynolds stress components have higher values at the inner half of the wake than at the outer half of the wake. However, the mean velocity defect profiles in similarity coordinates is almost symmetric and follows the same Gaussian function for the straight wake data. A comparison with the wake development in a curved channel at zero streamwise pressure gradient suggests that the decay rate of velocity defect is slower and the growth of wake width is faster in the case of positive streamwise pressure gradient. NOMENCLATURE wake width resultant velocity pressure coefficient momentum thickness ratio = 282/d diameter of wake generating cylinder frequency shape factor of wake curvature of wake centerline = I/R total number of samples per channel of hot-film data for time avenging p, � = Pin � = • =
Epithelial cell polarity and disease.

The establishment and maintenance of epithelial polarity is essential for the integrity and function of epithelial organs and is particularly critical in the kidney, where vectorial reabsorption an...
Special C44 Isomers

O’Keefe, Ross, and Baronavski, using laser vaporization of graphite and time-of-flight mass spectrometric detection have observed enhanced abundances of C+N cluster ions not only for n=50 and 60 but also for N = 44. Stimulated by this experimental result we have carried out a search for unusually stable C44 fullerene isomers. In this search, all possible 87 fullerene isomers of C44 were first generated and then classified according to the number of bonds, p, shared by abutting pentagons. We found that for C44 the minimum value of p is 8 and that there are only two C44 fullerenes with this value of p. Self-consistent geometry optimized calculations at the AM1 level show that these two special C44 fullerene isomers—although differing from one another by only about 0.1 eV in total energy—are over 1.0 eV more stable than any of the other possible 85 fullerene isomers of C44. These self-consistent-field calculations not only single out these two C44 fullerenes for special attention, but also further confirm the instability of abutting pentagons for lower fullerenes (those fullerenes with less than 60 carbon atoms).
Area and Volume Errors in Reservoir Projects

In reservoir planning-design, the engineer is facing the task of determining area of tracks of land, of surfaces covered by the reservoir water, and of the volumes of water contained in the reservoir at different water elevations. It is of fundamental importance to estimate the errors of these determinations in order to have a realistic look at the values obtained and their possible variations. In general, areas are measured from map directly by planimeters or computed from rectangular coordinates obtained by coordinatographs, and Volumes derived from contour areas. Areas and, consequently, volumes are affected by map and area measuring instrumentation errors. Formulas are presented to estimate these errors in general and specifically under the mapping standards commonly used in the United States. Because of its importance in reservoir planning-design, an example of the use of these formulas to the area-capacity curve determinations is included.
The Ecological Study of Emotions In Humans

Our emotions appear to us as beyond our rational control, a reminder of our animal heritage. We tend to regard them as primary and our cognitions as secondary, a thin veneer that evolved late and that remains under the influence of the emotional substrata. As will be seen shortly, there is a serious fallacy in this way of thinking, for while it considers what man shares in common with other animals, it fails to consider what is unique in the experience of human emotions. It fails to consider that underlying all emotional experience in humans are implicit cognitions.
Collard Greens, Clarence Thomas, and the High-Tech Rape of Anita Hill

Militant arguments that blacks now have no alternative except disruptive protests and boycotts will be invulnerable to more moderate responses. The Court's action will even give legitimacy to claims by some extremist leaders that black people must respond with violence to the violence inflicted on them by an uncaring society. History reveals no precedent for a black man in a position of real power advocating racial policies that are so at odds with the convictions of a great majority of his people. Thus, Judge Thomas must expect fierce criticism, first from blacks and then when they realize the racial chaos his decisions will
Abstract T MP66: Injury to the Head or Neck Increases Risk of Ischemic Stroke Three-fold After Trauma.

Background: Over 2 million people under age 50 are seen in a U.S. emergency room monthly for non-fatal injuries. Our objective was to measure ischemic stroke incidence after traumatic injury in young patients and identify stroke risk factors. Methods: We performed a population-based study of ischemic stroke after trauma among people <50 years old in a Northern Californian integrated health care system. We electronically identified a cohort of patients with diagnostic codes for trauma (ICD-9 800-959.9) in emergency and inpatient encounters from 1997-2011, then identified ischemic stroke outcomes within 4 weeks. To determine stroke, we required an ICD-9 stroke code (433-438) plus a radiology report of brain imaging containing a keyword: stroke, infarct#, thromb#, ischemi#, lacun#, or dissect#. A neurologist reviewed the reports to exclude those inconsistent with ischemic stroke. We obtained clinical data such as injury type from electronic databases to calculate stratified incidence rates and risk ratios. R...
Assessment of the Antibody Response to Pneumococcal Vaccine in High-Risk Populations

Vaccine-induced levels of antibody to Streptococcus pneumoniae of approximately 250-300 ng of antibody nitrogen/ml are protective against pneumococcal disease. Side effects of vaccination are not severe and are generally confined to local reactions at the site of inoculation. Patients with a documented high risk of acquiring pneumococcal disease include the elderly, especially those with underlying cardiopulmonary disease, and those with sickle cell anemia, Hodgkin's disease, a renal transplant, multiple myeloma, asplenia, and nephrotic syndrome. People with insulin-dependent diabetes mellitus or renal failure do not appear to be at high risk. All of these groups, except those with multiple myeloma, respond to vaccine with levels of antibody that are protective for many but not all of the serotypes included in the vaccine. Immunosuppression, splenectomy, and hemoglobinopathy depress antibody response. Duration of vaccine-induced antibody is unknown but may be shorter than that in normal persons. Preliminary guidelines for vaccination are proposed.
The Discussion on the Truth Norm and Party Theory Construction

The 1978 discussion on the Truth Norm is one of three times of thought liberation movement in China history.This discussion vividly criticizes the"Two Whatevers"erroneous views,puts forward that the practice is the sole criterion for testing truth,makes clear the right attitude on treating Marxism,MAO Zedong Thought.The Big Discussion re-established the ideological line of emancipating the mind and seeking truth from facts,which settled a correct political line and organizational line for the Third Plenary Session of the Eleventh Central Committee and the reform and opening-up,and had a profound historical meaning to socialism with Chinese characteristics,and the formation of idea system,especially DENG Xiaoping Theory.It is of great significance to inherit and carry forward the courage and pioneering spirit in the big discussion process,to the spirit of reform and innovation constantly perfection of party theory construction,and to carry forward the cause of socialism with Chinese characteristics.
The delivery of cottonseed meal at three different time intervals to steers fed low-quality grass hay: effects on digestion and performance.

A ruminal fermentation trial and a steer growth trial were conducted to evaluate the effects of time interval of cottonseed meal (CSM) supplementation of predominantly meadow fescue grass hay (GH; CP = 6.6%) on nutrient digestion and growth performance of beef steers. The fermentation trial used four ruminally cannulated steers assigned to a 4 x 4 latin square design with dietary treatments of GH fed alone (C) or GH supplemented with 3 g CP/kg BW.75 daily as supplied by CSM every 12, 24 or 48 h. Nylon bags containing GH were inserted into the rumen on d 1 and 2 of each collection period and incubated for 12, 24, 48 and 96 h to measure NDF and ADF degradation. Subsequently, steers were fed Yb-labeled GH and fecal samples were collected to determine particulate passage rate (PR). Dry matter and NDF intake, mean NDF and ADF in situ disappearance and ruminal VFA concentrations were greater (P less than .05) when CSM was fed; however, the delivery of CSM at various times did not affect (P greater than .10) these variables. Supplemented diets tended (P = .08) to have faster PR compared with the C diet. In the growth trial, CSM supplemented steers consumed more digestible DM (P less than .05) and had greater (P less than .05) daily gain compared with C steers. Effects due to time of CSM supplementation were not observed for the variables measured in the present study.
On the Mathematical Theory of Fluid Dynamic Limits to Conservation Laws

These lectures discuss topics in the theory of hyperbolic systems of conservation laws focusing on the mathematical theory of fluid-dynamic limits. First, we discuss the emergence of the compressible Euler equations for an ideal gas in the fluid-dynamic limit of the Boltzmann equation or of the BGK model. Then we survey the current state of the mathematical theory of fluid-dynamic limits for BGK systems and for discrete velocity models of relaxation type. This is done for the case that the limit is a scalar conservation law or a system of two equations.
High-performance face detection with CPU-FPGA acceleration

Face detection is a critical function in many embedded applications, such as computer vision and security. Although face detection has been well studied, detecting a large number of faces with different scales and excessive variations (pose, expression, or illumination) usually involves computationally expensive classification algorithms. These algorithms may divide an image into sub-windows at different scales, evaluate a large set of features for each sub-window, and determine the presence and location of a face. Even with state-of-the-art CPUs, it is still challenging to perform real-time face detection with sufficiently high energy efficiency and accuracy. In this paper, we propose a suite of acceleration techniques to enable such a capability on the CPU-FPGA platform, based on a state-of-the-art face detection algorithm that employs a large number of simple classifiers. We first map the algorithm using the integrated OpenCL environment for FPGA. Matching the structure of the algorithm, a nested architecture is proposed to speed up both memory access and the computing iterations. This multi-layer architecture distributes parallel computing cores with the memory. The physical aspects of the nested architecture, such as the core size and the number of cores, are further optimized to achieve real-time face detection, under realistic hardware constraints.
Fingerprinting Android packaging

Android's market experienced exponential popularity during the last few years. This blazing growth has, unfortunately, opened the door to thousands of malicious applications targeting Android devices everyday. Moreover, with the increasing sophistication of today's malware, the use of traditional hashing techniques for Android malware fingerprinting becomes defenseless against polymorphic malicious applications. Inspired by fuzzy hashing techniques, we propose, in this paper, a novel and comprehensive fingerprinting approach for Android packaging APK. The proposed fingerprint captures, not only the binary features of the APK file, but also the underlying structure of the app. Furthermore, we leverage this fingerprinting technique to build ROAR, an automatic system for Android malware detection and family attribution. Our experiments show that the proposed fingerprint and the ROAR system achieve a precision of 95%.
Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes

Islet inflammation promotes β-cell loss and type 2 diabetes (T2D), a process replicated in Zucker Diabetic Fatty (ZDF) rats in which β-cell loss has been linked to cannabinoid-1 receptor (CB1R)-induced proinflammatory signaling in macrophages infiltrating pancreatic islets. Here, we analyzed CB1R signaling in macrophages and its developmental role in T2D. ZDF rats with global deletion of CB1R are protected from β-cell loss, hyperglycemia, and nephropathy that are present in ZDF littermates. Adoptive transfer of CB1R-/- bone marrow to ZDF rats also prevents β-cell loss and hyperglycemia but not nephropathy. ZDF islets contain elevated levels of CB1R, interleukin-1β, tumor necrosis factor-α, the chemokine CCL2, and interferon regulatory factor-5 (IRF5), a marker of inflammatory macrophage polarization. In primary cultured rodent and human macrophages, CB1R activation increased Irf5 expression, whereas knockdown of Irf5 blunted CB1R-induced secretion of inflammatory cytokines without affecting CCL2 expression, which was p38MAPKα dependent. Macrophage-specific in vivo knockdown of Irf5 protected ZDF rats from β-cell loss and hyperglycemia. Thus, IRF5 is a crucial downstream mediator of diabetogenic CB1R signaling in macrophages and a potential therapeutic target.
Identifying the Space Buddies to Track Lost Items

Locating missing or lost objects has always been a challenging task. RFID technology and participatory sensing based approaches have offered solutions but often their adoption was limited due to the high hardware costs or low active participation problem. With the introduction of iBeacon technology and smartphones having BLE capability, tracking such objects has become easier and cost-effective. Objects of care are labeled by attaching to them affordable iBeacon tags, and smartphones in the proximity of these tags sense their presence opportunistically through the applications running in the background. In this paper, we study the tracking of lost objects through the collaboration among users. We analyze the visit patterns of users at the same locations and develop a metric that quantifies for each user the potential benefit of others in terms of their capability of finding that user's lost objects. Depending on the predicted benefits, each user's preference list of other users is formed and then utilized to identify the space buddies who can best track her lost items. The identification is based on the adaption of the solution to the roommate matching problem. We apply the proposed system to two different location based social network datasets and show its effectiveness in different settings.
Fixational Saccades and Their Relation to Fixation Instability in Strabismic Monkeys.

Purpose To evaluate the contribution of fixational saccades toward fixation instability in strabismic monkeys. Methods Binocular eye movements were measured as six experimental monkeys (five strabismic monkeys and one monkey with downbeat nystagmus) and one normal monkey fixated targets of two shapes (Optotype, Disk) and two sizes (0.5°, 2°) during monocular and binocular viewing. Fixational saccades were detected using an unsupervised clustering algorithm. Results When compared with the normal monkey, amplitude and frequency of fixational saccades in both the viewing and nonviewing eye were greater in 3 of 5 strabismic monkeys (1-way ANOVA on ranks P < 0.001; median amplitude in the normal monkey viewing eye: 0.33°; experimental animals: median amplitude range 0.20-0.82°; median frequency in the normal monkey: 1.35/s; experimental animals: median frequency range 1.3-3.7/s). Increase in frequency of fixational saccades was largely due to quick phases of ongoing nystagmus. Fixational saccade amplitude was increased significantly (3-way ANOVA; P < 0.001) but by small magnitude depending on target shape and size (mean difference between disk and optotype targets = 0.02°; mean difference between 2° and 0.5° targets = 0.1°). Relationship between saccade amplitude and the Bivariate Contour Ellipse Area (BCEA) was nonlinear, showing saturation of saccade amplitude. Fixation instability in depth was significantly greater in strabismic monkeys (vergence BCEA: 0.63 deg2-2.15 deg2) compared with the normal animal (vergence BCEA: 0.15 deg2; P < 0.001). Conclusions Increased fixational instability in strabismic monkeys is only partially due to increased amplitude and more frequent fixational saccades. Target parameter effects on fixational saccades are similar to previous findings of target effects on BCEA.
Geographies of production I: Global production and uneven development:

Serial crises in the global economy have spurred renewed debate over contemporary transformations in geographies of uneven development. Global production network (GPN) studies have not been inured ...
Sleep-disordered breathing and cognitive impairment in elderly Japanese-American men.

STUDY OBJECTIVE To assess the association between sleep-disordered breathing and cognitive functioning in an elderly cohort of Japanese-American men. DESIGN Cross-sectional study. SETTING The Honolulu-Asia Aging Study of Sleep Apnea, Oahu, Hawaii. PARTICIPANTS 718 men between 79 and 97 years of age examined in 1999 and 2000. MEASUREMENTS Apnea-hypopnea index from in-home overnight polysomnography, performance on the Cognitive Abilities Screening Instrument, body mass index, neck circumference, Epworth Sleepiness Scale, snoring, Center for Epidemiologic Studies Depression 11-item depression scale, physical disability, and history of heart disease, stroke, hypertension, diabetes, and dementia. RESULTS Less than 30% of the men had no sleep-disordered breathing (apnea-hypopnea index or = 30). Severe sleep-disordered breathing was associated with higher body mass index, habitual snoring, and daytime drowsiness. No association was found between sleep-disordered breathing and cognitive functioning, including measures of memory function, concentration, and attention. CONCLUSIONS Sleep-disordered breathing was associated with more drowsiness but not with poor performance on standardized cognitive tests used to screen for Alzheimer disease and other dementias in older persons. Because a healthy-participant effect may have contributed to this finding, more extensive cognitive testing may be necessary to reveal more subtle deficits from sleep-disordered breathing.
Epidemiology and Prevalence of Silent Myocardial Ischemia, and Prognosis in Asymptomatic Patients

Although heart disease is the nation’s number one killer, its presentation can take many forms. Some of these have only recently received the attention they deserve. For example, textbooks traditionally teach us that the natural history of coronary artery disease proceeds in an orderly fashion from a presymptomatic phase to angina to myocardial infarction to death. This is a stereotypical presentation that is not borne out by the facts. Data from epidemiologic surveys — such as the Framingham Study — suggest that for every individual who presents with angina, there is another one whose first manifestation of disease is either a myocardial infarction or sudden death. Autopsy studies performed in several centers over the last decade indicate that many of those who have sudden death as their first manifestation of coronary artery disease have had episodes of unrecognized infarction prior to the fatal event. Similarly, there is also data showing that prior painless ischemic events occur in patients who present with infarctions without antecedent angina.
Development of novel heat conduction interaction model for solid body thermal contact in CFD based particle flow simulations

Abstract Traditional computational fluid dynamics (CFD) simulations with resolved objects progressing through the fluid using a moving and deforming mesh require a fixed mesh topology. Though such simulations may more readily capture conditions where large gradients in the flow field exist, particularly high speed, compressible flow phenomena, the ability to directly model the conduction portion of the contact between particles or between particles and other solid bodies immersed in the fluid is thus restricted. A new method was devised to allow for the maintenance of the mesh topology while simulating the contact heat conduction between a discretized particle pair and between a discretized particle and a wall for the intended purpose of implementation of the technique within a computational fluid dynamics (CFD) based coupled particle–fluid flow model. The method is tested for a range of contact resistances (0–1 × 10−3 m2 K/W) and material thermal conductivity (1.60–162 W/m K) and specific heat (50.28–5028 J/kg-K) combinations with one object initially at 700 K and the other at 300 K. The temperature distributions across the mid-particle or mid-particle and wall line produced by the new method at a given time are compared to the results for a standard finite volume simulation of contacting bodies. The maximum difference in the local temperatures obtained is under 1%. Hence, the technique is a robust means of simulating the resolved heat conduction contact thermal energy exchange without connected computational elements, retaining the needed fluid gap space around the solid bodies. Future work will build upon this technique to include the convective and radiative modes of heat transfer before simulating moving and interacting particles in a fluid flow.
Abjection and Authoritarianism in 'I Am Legend' and its Remakes

In this paper I give an alternate and complementary reading of I Am Legend and its remakes, focusing on the psychodynamics behind authoritarian populism. My analysis is rooted primarily in Fromm’s theory of the authoritarian character ([1941]1994, [1955]2012, [1973]1992, 1984), Kristeva’s (1982) theory of abjection, and Sontag’s (1989) theory of plague as metaphor.
DAB-based WPT Charger with Integrated Battery Management System for Fast Charging of Mobility Devices

The wireless charging of electric mobility devices is a convenient charging method for people with physical disabilities and other potential users. Typically, a non-isolated converter is used at secondary of wireless chargers which lacks adequate protective features to keep the battery pack isolated from accidental fault conditions at the charger. Moreover, a CC-CV charge control method is generally used which does not take into account the cell-level imbalances in the battery, thereby is not ideal for ensuring battery longevity in a fast charging environment. In this paper, a solution to these issues is provided in the form of an isolated Dual Active Bridge (DAB)-based smart wireless charger design. The proposed Wireless Power Transfer (WPT) circuit employs smart battery charging features, including cell-level balancing and protection features. The designed WPT charger is implemented in an electric wheelchair system. The proposed charger is designed for about four times faster charging compared to conventional conductive wheelchair chargers. To accommodate the faster charging rate, a Li-ion replacement battery system having approximately the same volume but 66% more capacity compared to typical Sealed Lead-Acid (SLA) wheelchair batteries is deployed.
piRNA-unbound PIWIL1 promotes metastasis.

Piwi proteins are aberrantly induced in human tumours, but their function in cancer has been poorly understood. A study now shows that in the absence of piRNA loading, human PIWIL1 promotes pancreatic cancer metastasis by acting as a co-activator of the anaphase-promoting complex/cyclosome (APC/C) to degrade the cell-adhesion protein Pinin.
12 – Excerpts: Single-Session Therapy

Publisher Summary This chapter presents two single session therapy excerpts that illustrate different components of the model. In first session, doctor examines Mary, age fifty, was divorced; she worked as a nurse's aide. She was feeling depressed, was having trouble sleeping, and found herself tearful. The therapist's attempts to clarify Mary's primary complaint were not working. At this point it seems unlikely that “more of the same” will make things much clearer, so it was time to shift gears. The therapist then decided to ask the miracle question. The therapist reviewed the treatment options available to Mary. Mary wanted Dr. Calhoun to continue to prescribe her medication. Mary did not feel that she needed an individual follow-up appointment, but she expressed interest in joining a women's group. In second session, Doctor examines Liz; she was a forty-three-year-old, divorced college administrator who called for an appointment for “relationship problems.” This excerpt illustrates the therapist's attempts to determine who is the “customer” and what is the “complaint.”
Current View of Ligand and Lipid Recognition by the Menthol Receptor TRPM8

Transient receptor potential (TRP) melastatin member 8 (TRPM8), which is a calcium-permeable ion channel, functions as the primary molecular sensor of cold and menthol in humans. Recent cryoelectron microscopy (cryo-EM) studies of TRPM8 have shown distinct structural features in its architecture and domain assembly compared with the capsaicin receptor TRP vanilloid member 1 (TRPV1). Moreover, ligand-bound TRPM8 structures have uncovered unforeseen binding sites for both cooling agonists and membrane lipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]. These complex structures unveil the molecular basis of cooling agonist sensing by TRPM8 and the allosteric role of PI(4,5)P2 in agonist binding for TRPM8 activation. Here, we review the recent advances in TRPM8 structural biology and investigate the molecular principles governing the distinguishing role of TRPM8 as the evolutionarily conserved menthol receptor.
A Critical Sociocultural Cross-Case Analysis

In this chapter, we bring together the four testimonios to illustrate the themes and nuances of their counternarratives that “strengthen traditions of social, political, and cultural survival and resistance” (Solorzano & Yosso, 2002, p. 32). Indeed, the testimonialistas are doing far more than surviving; they are decidedly resisting a monolithic view of their lives through their acts of literacies and languaging. Studying literacies and languaging through this lens allows us to understand how those who seamlessly move between multiple literacies and languaging and/or simultaneously employ them successfully for specific purposes generate community cultural wealth. We further discuss how a raciolinguistic application of Bourdieu’s (1986) terminology (Chapter 4), capital, fields, and habitus, works toward countering doxa in our testimonalistas’ lives.
Increasing Rates of Opioid Prescriptions for Gastrointestinal Diseases in the United States.

Introduction Pain control is an important management approach for many gastrointestinal conditions. Because of the ongoing opioid crisis, public health efforts have focused on limiting opioid prescriptions. This study examines national opioid prescribing patterns and factors associated with opioid prescriptions for gastrointestinal conditions. Methods We conducted a repeated cross-sectional study using the National Ambulatory Medical Care Survey data from 2006 to 2016. The International Classification of Diseases codes were used to identify ambulatory visits with a primary gastrointestinal diagnosis. Data were weighted to calculate national estimates for opioid prescriptions for gastrointestinal disease. Joinpoint regression was used to analyze temporal trends. Multivariable logistic regression was used to examine factors associated with opioid prescriptions. Results We analyzed 12,170 visits with a primary gastrointestinal diagnosis, representing 351 million visits. The opioid prescription rate for gastrointestinal visits was 10.1% (95% confidence interval [CI] 9.0%-11.2%). Opioid prescription rates for gastrointestinal disease increased by 0.5% per year from 2006 to 2016 (P = 0.04). Prescription rates were highest for chronic pancreatitis (25.1%) and chronic liver disease (13.9%) visits. Seventy-one percent of opioid prescriptions were continuations of an existing prescription. Patient characteristics associated with continued opioid prescriptions included rural location (adjusted odds ratio [aOR] 1.46; 95% CI 1.11-1.93), depression (aOR 1.83; 95% CI 1.33-2.53), and Medicaid insurance (aOR 1.57; 95% CI 1.15-2.13). Discussion Opioid prescription rates for gastrointestinal disease visits increased from 2006 to 2016. Our findings suggest an inadequate response to the opioid epidemic by providers managing gastrointestinal conditions. Further clinical interventions are needed to limit opioid use for gastrointestinal disease. See the visual abstract at http://links.lww.com/AJG/B788.
Prediction of Thyroid Hormone Replacement Following Thyroid Lobectomy: A Long-term Retrospective Study.

ObjectiveFollowing thyroid lobectomy, patients are at risk for hypothyroidism. This study sought to determine the incidence of postlobectomy thyroid hormone replacement as well as predictive risk f...
Love’s Resistance: Heidegger and the Problem of First Philosophy

This paper offers a reading of passages in Heidegger’s Nietzsche lectures in which Heidegger describes love as a feeling which grants an essential vision. I contend that by invoking this language o...
Differential levels of serum PSA related to volume of benign, Gleason pattern 3 and pattern 4 prostate tissue.

164Background: PSA is an essential component of prostate cancer screening, management, and oncologic risk. We evaluated how serum levels of PSA vary by volume of benign tissue, Gleason pattern 3 (G...
Emergent learning in the emergency

In the following papers, three writing teachers describe how they learned to work under the conditions of the Covid emergency, what principles helped them find their way, and what new realizations they came to which may impact their teaching going forward. While no one has the final answer, each of them provides important tools that might help each of us reflect on our own experience and help us find our teaching way through the rest of this emergency and beyond.
Tacit Knowledge and Innovation: Insights from the Public Sector in Delta State, Nigeria

This study empirically investigated the relationship between tacit knowledge and innovation from the public sector context in Delta State, Nigeria. The use of tacit knowledge for innovation has bee...
Designing Clothes: Culture and Organization in the Fashion Industry

Book review by Lisa Hayes. Manlow, Veronica. Designing Clothes: Culture and Organization in the Fashion Industry. New Brunswick, NJ: Transaction Publishers, 2007. ISBN 9781412810555