cssi/SciSciGPT-SciSciNet huggingface dataset:
The Influence of Communication- and Organization-Related Factors on Interest in Participation in Campus Dialogic Deliberation

Grounded in participatory democracy principles, deliberation is designed to foster collaborative and thoughtful decision-making communication. On college campuses, deliberation can lead to a number of individual and organizational consequences, particularly for students, who may not believe that they have a significant voice in decision-making. Although deliberation ostensibly enables students to make their voices heard, the factors that shape students’ interest in participation in such deliberation remain unclear. This study explored how communication and campus factors influence students’ interest in and perceived helpfulness of dialogic deliberation participation. This manuscript concludes with recommendations for the development of campus-based and community-oriented deliberation programs.
The challenges of closing an ileostomy in patients with total intestinal aganglionosis after small bowel transplant.

We present the case of a 14-year-old male with a history of small bowel transplantation for long segment Hirschsprung’s disease who underwent Duhamel ileorectal pull-through procedure. In post-transplant, the patient had no restrictions and was not TPN-dependent. To improve his quality of life, he and his family were interested in closing the ileostomy and undergoing pull-through surgery. The complexity of the case includes the presence of an aganglionic rectal segment—a short root of the mesentery due to the small bowel transplant—and significant immunosuppression. At the moment, he is continent, doing well, and has not had any remarkable complications.
Stratigraphic and Paleobiogeographic Distribution of Arthrophycus

ABSTRACTIchnofossils attributed to the ichnogenus Arthrophycus (Hall 1852) have been reported from localities worldwide, including all seven modern-day continents. Arthrophycus is most abundant in Ordovician and Silurian strata and is widely regarded as an ichnostratigraphic indicator of this interval. Occurrences of the ichnogenus from younger strata have been reported, but there is growing consensus that post-Paleozoic records of Arthrophycus are not valid. The oldest confirmed occurrence of Arthrophycus is A. minimus (Mangano et al. 2005a) from the Upper Cambrian of Argentina, South America. The youngest confirmed report is A. parallelus (Brandt et al. 2010) from the Upper Carboniferous (Pennsylvanian) of the Michigan Basin, USA. Paleobiogeographic analysis based on the five most widely accepted ichnogenera confirms the hypothesis that Arthrophycus originated in Gondwana during the Late Cambrian and Early Ordovician, expanded to the northern continents during the Mid-Late Ordovician, reaching its acme ...
Fiber Deficiency and the Irritable Colon Syndrome

It would be reasonable to question whether a discussion of the irritable colon syndrome should be included in this meeting. The thought is prompted not by any notion that the irritable colon is an unimportant condition, but rather from the difficulties in arriving at a universally acceptable definition of the disorder based upon objective criteria. This uncertainty leads to multiple difficulties in measurement—in being restricted to gross estimates of prevalence at different ages and in different populations, and in accommodating to great uncertainty about its epidemiology and its clinical course. As a result, hypotheses regarding etiology and therapy always have been difficult to validate.
Adolescents' reactions to hypothetical peer group conversations : Evidence for an imaginary audience?

The theory of adolescent egocentrism holds that early adolescents have a distorted understanding of self-other relations; because of flaws in the traditional methods used to assess adolescent egocentrism, this notion has never received adequate empirical scrutiny. In the present research, the nature of early adolescent social cognition as characterized by that theory was investigated by examining age differences in judgments of hypothetical peer group conversations. In Study 1, children and early adolescents (N = 264) rated the attentiveness, criticalness, and admiration expressed in three conversations, in which the subject or a peer was mentioned in either an admiring, critical, or nonevaluative manner. In Study 2, a similar procedure was used with middle and late adolescents, as well as children and early adolescents (N = 187); two memory tasks were also administered to visit the issue of distortion in social cognition. In Study 3, a new sample (N = 1,019) representing the four age groups from Study 2 was presented with an ambiguous conversation and then asked to interpret who was the target (object of focus) and how that target was regarded. The findings from the three studies do not support the notion that adolescents believe others are attentive to and critical of their every move, or that their social cognition and perception is egocentric and distorted. Conceptual and methodological contributions are discussed, along with directions for additional research.
A Jew of a rather peculiar sort: Leonard Woolf, Jewishness, and a public 20th century life

ABSTRACTLeonard Woolf (1880–1969) was a prominent British writer and international relations theorist for the Labour Party. Despite being born Jewish, scholars have long considered Woolf to have abandoned his Jewishness as the price of acceptance into wider English society, particularly the Bloomsbury literary movement with which he is associated. This article offers a different perspective, showing how Woolf constructed an alternative and positive Jewish identity. In particular, this article suggests that Woolf’s criticisms of British cultural practices and his support of international institutions that emerged after World War One were bound up with Jewish themes, ethics, and values.
On the Unsteady Supersonic Cascade With a Subsonic Leading Edge—An Exact First Order Theory—Part 1

This paper presents, in two parts, the theoretical predictions of the aerodynamic forces acting on slowly oscillating airfoils in a supersonic cascade with a subsonic leading edge. The analysis is based on the assumption of an inviscid, two-dimensional and linearized flow. In the first part of the paper, the flow field ahead of the cascade is considered. An initial value problem is posed and, from the periodicity requirement in the cascade, the problem is reformulated in terms of integral equations. Solution of the integral equations, accurate to the first order of a frequency parameter, are obtained in closed form. In the limit of the steady flow, the unsteady flow analysis yields a mathematical verification of the unique incidence effect. Based on this proof, a simple rule is presented for the airfoil suction surface contour satisfying steady flow requirement ahead of the cascade. The complete aeroelastic problem, including the solution for the flow field between the blades and the trailing interference zone, is treated in Part 2.
Perinatal Risk Factors for the Retinopathy of Prematurity in Postnatal Growth and Rop Study.

Objective: To evaluate perinatal risk factors for retinopathy of prematurity (ROP), in a large, broad-risk cohort of premature infants. Study design: Secondary analysis of data from the Postnatal Growth and ROP (G-ROP) Study, a retrospective cohort study of infants undergoing ROP examinations at 29 North American hospitals in 2006-2012. Results: Among 7483 infants, 3224 (43.1%) had any ROP and 931 (12.4%) had severe ROP (Type 1 or 2 ROP). In multivariable logistic regression analysis, significant risk factors for any ROP were lower birth weight (BW, odds ratio (OR) = 5.2, 1250 g), younger gestational age (GA, OR = 32, 29 weeks), 1-min Apgar score 1250 g), younger GA (OR = 30, 29 weeks), male (OR = 1.5), Hispanic ethnicity (OR = 1.8), race (OR = 1.6, White vs. Black), outborn (OR = 1.6), and delivery room intubation (OR = 1.6). Together, these factors predicted well for any ROP (area under ROC curve (AUC) = 0.87) and severe ROP (AUC = 0.89), but BW and GA were the dominant factors for ROP (AUC = 0.86) and severe ROP (AUC = 0.88). Conclusions: Based on the largest report to date with detailed ROP data from infants meeting current screening guidelines, ROP risk is predominantly determined by the degree of prematurity at birth, with other perinatal factors contributing minimally.
Mechanisms contributing to the genesis of hypoglossal preinspiratory discharge

Preinspiratory discharge manifests in the neuronal recordings of the pre-Botzinger complex, parafacial respiratory group, retrotrapezoid nucleus, and Kolliker-Fuse nucleus, as well as the efferent neural discharge of respiratory-related nerves innervating upper airway musculature. This neural component of triphasic eupnea contemporaneously contributes to the genesis of native and originate respiratory rhythmic activity, as well as the preinspiratory component of efferent neural respiratory discharges. In the course of our investigations evaluating hypoglossal discharge in response to asphyxia, we noted a curious pattern of neural respiratory recovery following postasphyxia resuscitation in hypoglossal, vagal, and phrenic neurograms in unanesthetized decerebrate rats. Specifically, we observed a gradual return of a pseudobiphasic eupnea characterized by initial transition bursts followed by robust eupneic bursts with dynamics inclusive of a gradually and progressively increasing duration of the hypoglossal eupneic bursts and duration and amplitude of the preinspiratory component of these bursts, as well as progressively lengthening expiratory interval between these bursts in the phrenic nerve discharge. This was followed by conversion to regular triphasic eupnea. We discuss our extrapolations based on these findings regarding eupneic respiratory central pattern generation and mechanisms contributing to the genesis of preinspiratory activity in hypoglossal discharge.
Applied Human Factors in Medical Device Design, 1st ed

If you aspire to be involved in the proper design, development, testing, documentation, sales, or manufacture of (improved) medical devices, this text offers a comprehensive overview of the many standards and methodologies involved in the process of applying human factors analysis in the medical device design process. To a large extent, its many chapters offer guidelines and examples of various aspects specific to recommended U.S. and European design documentation standards and requirements.
Anesthesia Exposure during Therapy Predicts Neurocognitive Outcomes in Survivors of Childhood Medulloblastoma

Objective To examine the contribution of anesthesia exposure during treatment for childhood medulloblastoma to neurocognitive outcomes 3 years after tumor diagnosis. Study design In this retrospective study, anesthesia data were abstracted from medical records for 111 patients treated with risk-adapted protocol therapy at St Jude Children's Research Hospital. Neurocognitive testing data were obtained for 90.9% of patients. Results For the 101 patients (62.4% male) who completed testing, mean age at diagnosis was 10.1 years, and 74.3% were staged to have average-risk disease. Anesthesia exposure during treatment ranged from 1 to 52 events (mean = 19.9); mean cumulative duration per patient was 21.1 hours (range 0.7–59.7). Compared with normative expectations (16%), the group had a significantly greater frequency of at-risk scores ( Conclusions In survivors of childhood medulloblastoma, a neurodevelopmentally vulnerable population, greater exposure to anesthesia significantly and independently predicts deficits in neurocognitive and academic functioning. When feasible, anesthesia exposure during treatment should be reduced.
Abstract 1426: A PI3K/AKT scaffolding protein, IQ motif-containing GTPase associating protein 1 (IQGAP1), promotes head and neck carcinogenesis

Purpose: Head and neck cancer (HNC) is the sixth most common cancer worldwide with a 5-year survival rate of less than 50%. The PI3K/AKT/mTOR signaling pathway is frequently implicated in HNC. Recently, IQ motif-containing GTPase activating protein 1 (IQGAP1) was discovered to scaffold the PI3K/AKT signaling pathway. IQGAP1 gene expression is increased in HNC, raising the hypothesis that IQGAP1 contributes to HNC. Experimental Design: We performed a combination of in vitro studies using human cancer cell lines treated with a cell permeable peptide that interferes with IQGAP19s ability to bind to PI3K, and in vivo studies utilizing mice genetically knocked out for the Iqgap1 (Iqgap1-/-). In vivo EGF-stimulation assays were used to evaluate PI3K signaling. To study the role of IQGAP1 in HNC, we used a well-validated mouse model that drives HNC via a synthetic oral carcinogen, 4-nitroquinoline 1-oxide (4NQO). Results: IQGAP1 is necessary for efficient PI3K signaling in vitro and in vivo. Disruption of IQGAP1-scaffolded PI3K/AKT signaling reduced HNC cell survival. Iqgap1-/- mice had significantly lower cancer incidences, lesser disease severity and fewer cancer foci. IQGAP1 protein levels were increased in HNC arising in Iqgap1+/+ mice. The level of PI3K signaling in 4NQO-induced HNC arising in Iqgap1-/- mice was significantly reduced, consistent with the hypothesis that IQGAP1 contributes to HNC at least partly through PI3K signaling. High IQGAP1 expression correlated with reduced survival, and high pS6 levels correlated with high IQGAP1 levels in HNC patients. Conclusions: These data demonstrate that IQGAP1 contributes to head and neck carcinogenesis. Citation Format: Tao Wei, Suyong Choi, Darya Buehler, Richard A. Anderson, Paul F. Lambert. A PI3K/AKT scaffolding protein, IQ motif-containing GTPase associating protein 1 (IQGAP1), promotes head and neck carcinogenesis [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 1426.
More on Heine’s Formula and the General Binomial

Inspired by (13.16) and (13.17), it is natural to generalize the notion of a q-binomial in the following way.
The Atmospheres of the Terrestrial Planets: Clues to the Origins and Early Evolution of Venus, Earth, and Mars

We review the current state of knowledge of the origin and early evolution of the three largest terrestrial planets - Venus, Earth, and Mars - setting the stage for the chapters on comparative climatological processes to follow. We summarize current models of planetary formation, as revealed by studies of solid materials from Earth and meteorites from Mars. For Venus, we emphasize the known differences and similarities in planetary bulk properties and composition with Earth and Mars, focusing on key properties indicative of planetary formation and early evolution, particularly of the atmospheres of all three planets. We review the need for future in situ measurements for improving our understanding of the origin and evolution of the atmospheres of our planetary neighbors and Earth, and suggest the accuracies required of such new in situ data. Finally, we discuss the role new measurements of Mars and Venus have in understanding the state and evolution of planets found in the habitable zones of other stars.
Sports Participation in Patients with Congenital Long QT Syndrome

Congenital long QT syndrome (LQTS) is an inherited channelopathy that can manifest as sudden cardiac death in the absence of morphologic heart disease. Corrected QT interval (QTc) is typically calculated using Bazett’s formula of QTc = QT interval/√RR on the 12-lead electrocardiogram (ECG). Suspicion for the diagnosis of LQTS should be based upon a QTc exceeding 470 milliseconds (ms) in males and 480 ms in females. About 75–80% of patients with LQTS have identifiable genetic variants with variable penetrance. The most common subtype is LQT1 in which arrhythmia is triggered by exercise, particularly swimming. The less common subtypes are LQT2 and LQT3 in which arrhythmias are triggered by auditory stimuli and during sleep, respectively. The mainstay of treatment for LQTS is beta blockers which have been shown to reduce the risk of sudden cardiac death. Nadolol and propranolol have been demonstrated to have the best efficacy. Sports participation guidelines have become less restrictive as studies have demonstrated that episodes of sudden cardiac death are not as high as previously thought, particularly with avoidance of QT prolonging medications and adherence to proper medical treatment with beta blockers. It is crucial to review risk stratification with athletes with LQTS and utilize shared decision making to come to a consensus for sports participation on a case-by-case basis. Safety precautions at practices and games must be utilized such as having an AED on-site, avoidance of dehydration, and establishing an emergency action plan with the appropriate school/team officials.
Role of Metabolic Factors: Lipids, Glucose/Insulin Intolerance

Overnutrition characterized by overconsumption of food rich in fat and carbohydrates is a significant contributor to hypertension, type 2 diabetes, and the cardiorenal syndrome (CRS). Obesity, insulin resistance, and diabetes mellitus are associated with a substantially increased prevalence of arterial disease (AD), which is involved in the risk of coronary, cerebral, and peripheral atherosclerosis and the clinical consequences of myocardial infarction, stroke, limb ischemia, and death. Although the underlying mechanisms and mediators of AD are not well understood, accumulating evidence supports the role of dysregulation of VSMCs, ECs, and vascular extracellular matrix in pathogenesis of AD. Risk factors related to CRS and misregulation of adaptive metabolic responses develop a complex network and contribute to the progression of AD. In this review, we will focus on the interaction of metabolic risk factors, adaptive metabolic response, and AD, highlighting pathophysiology and molecular mechanisms, as well as the contemporary understanding of potential therapeutic strategies.
Consumer Service Satisfaction: Some Research Insights

Our presentation looks at recent research on consumer satisfaction, then discuss a conceptualisation of the disconfirmation paradigm suitable for service encounters proposed by Walker (1995). Some research ideas for a better understanding of the service encounter satisfaction process are also presented.
Coordination of Reaching and Grasping in Prosthetic and Normal Limbs

An experienced user of a body powered voluntary-close upper extremity prosthesis was studied while tending to the task of grasping a vertical cylindrical object. Trials of repeated grasps were carried out under three different speeds of action. Similar trials were run using the subject’s normal right hand. Findings for the normal hand are consistent with previous studies by Fraser & Wing (1981) and Wing & Fraser (1983) in that the thumb tended to deviate significantly less from a straight line trajectory to the target than did the index finger. In the prosthetic hand, the moveable “thumb” maintained a straight line course toward the target while the fixed portion of the prehensor was moved normal to the trajectory in a manner which accounted for change in the aperture. Maximum aperture was greatest for the fast grasp in both prosthetic and normal hands. Other findings show significantly greater variability in most measures of the normal hand grasp compared to the prosthetic grasp. In general, the findings suggest multiple, but less variable, temporal patterns of coordination between transport and manipulation in the prosthetic compared to the normal hand.
Model system to study interaction of platelets with damaged arterial wall. I. Inhibition of platelet adhesion to subendothelium by aspirin and dipyridamole.

Abstract An experimental model system has been developed to study the interaction of platelets with a damaged vessel wall, in vivo , without deep surgical intervention. Endothelium of the central ear artery of an anesthetized rabbit is damaged by placing artery forceps on the ear directly over the vessel. Forceps are removed 30 min later and blood flow resumes. After 30 min, blood is washed out with Tyrode's solution and the vessel is perfused with 1% glutaraldehyde solution. Tissue containing the vessel is then removed and further prepared for scanning and transmission electron microscopy. Damage to the endothelium observed by scanning electron microscopy included separation of adjacent endothelial cells (EC); partial destruction and lifting up of some EC, exposing subendothelium; and denudation of larger areas of endothelium. Disc-shaped platelets were seen clinging to some damaged endothelial cells. Platelets adhered, formed pseudopods, and spread over the surface of some areas of exposed subendothelium. The extent of platelet adhesion to exposed subendothelium was estimated by eight “blind” evaluators and the average taken. Aspirin (8 mg/kg, ip) significantly inhibited adhesion ( P P P
Experimental study of the orientation dependence of indium incorporation in GaInN

Abstract Indium incorporation was studied on a wide variety of planes tilted from the c-plane towards either the a-plane or the m-plane, as well as on two additional planes that were tilted with respect to the a- and m-planes but normal to the c-plane. It was found that the indium content and the photoluminescence wavelength variation patterns are similar. The growth rates do not vary significantly with orientation except for (10-13) and (10-1-3). Indium incorporation was found to increase with reactor pressure except for (10-1-2) and (20-2-7). The change in indium incorporation efficiency with growth temperature is found to depend on the orientation.
Genetic Distances and Reconstruction of Phylogenetic Trees From Microsatellite DNA

Recently many investigators have used microsatellite DNA loci for studying the evolutionary relationships of closely related populations or species, and some authors proposed new genetic distance measures for this purpose. However, the efficiencies of these distance measures in obtaining the correct tree topology remains unclear. We therefore investigated the probability of obtaining the correct topology (PC) for these new distances as well as traditional distance measures by using computer simulation. We used both the infinite-allele model (IAM) and the stepwise mutation model (SMM), which seem to be appropriate for classical markers and microsatellite loci, respectively. The results show that in both the IAM and SMM CAVALLI-SFORZA and EDWARDS’ chord distance (Dc) and NEI et al.’s DA distance generally show higher PC values than other distance measures, whether the bottleneck effect exists or not. For estimating evolutionary times, however, NEI’S standard distance and GOLDSTEIN et aL’s (6~)‘ are more appropriate than other distances. Microsatellite DNA seems to be very useful for clarifymg the evolutionary relationships of closely related populations.
Egyptian Popular Culture in Wide Array

Mass Culture and Modernism in Egypt. Walter Armbrust New York: Cambridge University Press, 1996.275 pp.
Early Childhood Teacher Education in Ethiopia: Progress and Emerging Challenges

This article extends concerns of our National Association of Early Childhood Teacher Educators (NAECTE) membership beyond the borders of the United States to the continent of Africa. Specifically, it explores the current status of early childhood teacher education in one of the poorest nations of the world—Ethiopia. It includes an analysis of recent policy developments as well as continuing challenges to educational progress. The article concludes with a call for like-minded professional organizations such as NAECTE to lend its expertise and support to this struggling nation.
Piecewise‐linear modelling and simulation of nonlinear networks

This paper presents a method which combines the modelling and simulation of a nonlinear network together. The main idea is to divide the rectangle of interest into simplices by imposing a fixed ordering. It turns out that the creation of a piecewise-linear model and the computation of an approximate solution are greatly simplified because of the use of simplices. Some examples show that it is possible to apply the method to ‘fixed point’ problems and other types of problems.
On the definition of lying: A reply to Jones and revisions

Standard definitions of lying imply that intending to deceive others is a necessary condition of one's telling a lie. In an earlier paper, which appeared in this journal, Wokutch, Murrmann and I argued that intending to deceive others is not a necessary condition of one's telling a lie and proposed an alternative definition. In a reply which also appeared in this journal, Gary Jones argues that (1) our arguments fail to establish the claim that it is possible to lie without intending to deceive others, and that (2) the objections which we raise for standard definitions apply equally to our own. The present paper argues that one can lie without intending to deceive others. I concede Jones' second criticism and propose a new alternative definition.
Low-density lipoprotein particle size, triglycerides, and high-density lipoprotein cholesterol as risk factors for coronary heart disease in older Japanese-American men

Decreased low-density lipoprotein (LDL) particle size is associated with coronary heart disease (CHD) risk among middle-aged Caucasian populations, and has been consistently correlated with increased plasma levels of triglyceride and decreased levels of high-density lipoprotein (HDL) cholesterol. This study examines whether these risk factors predict CHD among older Japanese-American men. With use of the Honolulu Heart Program Lipoprotein Exam 3 (1980 to 1982) as baseline, and 12-year follow-up for CHD events, a nested, case-control study was designed. One hundred forty-five incident CHD cases were identified and matched to 2 controls each. LDL particle diameter (size) was determined by gradient gel electrophoresis. A 10-angstrom (A) decrease in LDL size at baseline was associated with increased risk of incident CHD (relative risk 1.28, 95% confidence interval 1.01 to 1.63). After adjustment for baseline risk factors, the LDL size association was no longer statistically significant (relative risk 1.13, 95% confidence interval 0.86 to 1.49). When principal components analysis was used to define a composite variable for LDL size, triglycerides, and HDL cholesterol, this component predicted CHD independent of smoking, alcohol consumption, physical activity, body mass index, hypertension, diabetes, and beta-blocker use (p <0.01). Therefore, this prospective analysis of data from older, Japanese-American men demonstrated that decreased LDL size is a univariate predictor of incident CHD, and that a composite risk factor of LDL size, triglyceride, and HDL cholesterol was a risk factor for CHD independent of other risk factors.
TESTING OF A HIGH PERFORMANCE COMPRESSOR DISCHARGE SEAL

cation and test evaluation phase. This paper deals with GMA 101, a FRFS system would result in a 1.5% testing and results of the rig evaluation of the scals. Several alternative hydrostatic and hydrodynamic imProvement in cycle specific fuel consumption (SFC) FRFS designs were considered in the desi@ phase, compared to using a conventional labyrinth seal sysFilm stiffness, leakage and heat generation Were sc- tcm. While brush seal technology has recently adlected to be thc most important design cfitcria. llsing vanced to the point where these seals arc bcing used these ,.riteria, hydrodynamic seals proved supc.ior to for compressor discharge seals (such as on the Allison the hydrostatic designs. Spiral groove desigtl ad '1'406 engine for the (V-22), brush seals have not yet ~~~l~igh step pad sea[s were for dct&l demonstrated the capability to seal effectively at the design and fabrication. high levels of pressure differcntial required for an advanced engine. the high pressure
Compound-nuclear reaction cross sections from surrogate measurements

Nuclear reaction cross sections are important for a variety of applications in the areas of astrophysics, nuclear energy, and national security. When these cross sections cannot be measured directly or predicted reliably, it becomes necessary to develop indirect methods for determining the relevant reaction rates. The surrogate nuclear reactions approach is such an indirect method. First used in the 1970s for estimating ðn; fÞ cross sections, the method has recently been recognized as a potentially powerful tool for a wide range of applications that involve compound-nuclear reactions. The method is expected to become an important focus of inverse-kinematics experiments at rareisotope facilities. The present paper reviews the current status of the surrogate approach. Experimental techniques employed and theoretical descriptions of the reaction mechanisms involved are presented and representative cross section measurements are discussed.
Homosexuality and the Pediatrician Early Recognition and Preventive Counselling

Homosexuality is a psychiatric syn drome which begins in childhood. By rec ognizing some of the predisposing factors early, and then using his influence and knowledge to work towards their correc tion, the pediatrician can often play a ma jor role in preventing its development.Homosexuality must be looked upon as the illness which it is. It is not just a "different way of life."
Limitations of the Power Spectral Density as an Indicator of Test Severity

This paper presents a set of experimental data comparing repetitive shock (RS) vibration, single-axis electrodynamic (ED) vibration, and multi-axis ED vibration. It was found that multi-axis testing is more severe than single-axis testing at the same level. In addition, weaknesses were found in the RS system at low frequency. Smoothing of the data or poor line resolution was also shown to change the overall severity of a test. A poor correlation was shown between the power spectral density (PSD) and the rate of natural frequency change (RFC) over a wide frequency shift. The change in natural frequency caused the initial PSD to be an ineffective indicator of test severity. Quantification of the severity of the test profile can be accomplished through characterization of the RFC.
School-college collaborations: A strategy for helping low-income minorities

Today, with all the talk about educational excellence, schools and colleges still live in two separate worlds. Presidents and deans rarely talk to principals and district superintendents. College faculty do not meet with their counterparts in public schools, and curriculum reforms at every level are planned in isolation. It's such a simple point—the need for close collaboration—and yet it is a priority that has been consistently ignored. Universities pretend they can have quality without working with the schools, which are, in fact, the foundation of everything universities do.
Ceramic thin film thermocouples for SiC-based ceramic matrix composites

Abstract Conductive ceramic thin film thermocouples were investigated for application to silicon carbide fiber reinforced silicon carbide ceramic matrix composite (SiC/SiC CMC) components. High temperature conductive oxides based on indium and zinc oxides were selected for testing to high temperatures in air. Sample oxide films were first sputtered-deposited on alumina substrates then on SiC/SiC CMC sample disks. Operational issues such as cold junction compensation to a 0 °C reference, resistivity and thermopower variations are discussed. Results show that zinc oxides have an extremely high resistance and thus increased complexity for use as a thermocouple, but thermocouples using indium oxides can achieve a strong, nearly linear response to high temperatures.
The abundance and activation of mTORC1 regulators in skeletal muscle of neonatal pigs are modulated by insulin, amino acids, and age

Mammalian target of rapamycin complex 1 (mTORC1) signaling is crucial for the regulation of protein synthesis. Most of known mTORC1 regulators have been isolated and characterized using cell culture systems, and the physiological roles of these regulators have not been fully tested in vivo. Previously we demonstrated that the insulin (INS) and amino acid (AA)-induced activation of mTORC1 is developmentally regulated in skeletal muscle (Suryawan A et al. Am J Physiol Endocrinol Metab 293: E1597-E1605, 2007). The present study aimed to characterize in more detail the effects of the postprandial rise in INS and AA on the activation and abundance of mTORC1 regulators in muscle and how this is modified by development. Overnight fasted 6- and 26-day-old pigs were studied during 1) euinsulinemic-euglycemic-euaminoacidemic conditions (control), 2) euinsulinemic-euglycemic-hyperaminoacidemic clamps (AA), and 3) hyperinsulinemic-euglycemic-euaminoacidemic clamps (INS). INS, but not AA, enhanced the PRAS40 phosphorylation, and this effect was greater in 6- than in 26-day old pigs. Phospholipase D1 (PLD1) abundance and phosphorylation, and the association of PLD1 with Ras homolog enriched in brain (Rheb), were greater in the younger pigs. Neither INS, AA, nor age altered the abundance of Rheb, vacuolar protein sorting 34 (Vps34), or FK506-binding protein 38 (FKBP38). Although INS and AA had no effect, the abundance of ras-related GTP binding B (RagB) and the association of RagB with Raptor were greater in 6- than in 26-day-old pigs. Neither INS, AA, nor age altered AMPK-induced phosphorylation of Raptor. Our results suggest that the enhanced activation of mTORC1 in muscle of neonatal pigs is in part due to regulation by PRAS40, PLD1, and the Rag GTPases.
Comparative aggression in Sceloporus virgatus, S. undulatus consobrinus, and S. u. tristichus (Sauria: iguanidae).

Abstract Aggressive behaviour in both sexes of Sceloporus virgatus, S. undulatus consobrinus , and S. u. tristichus were compared by introducing a conspecific to a resident lizard in the field. Males of S. u. consobrinus exhibited high intensity aggression more commonly than did males of the other forms. Of the females, S. u. tristichus showed the greatest propensity for aggressive behaviour; S. u. consobrinus showed the least. In males, degree of aggression was correlated positively with degree of sexual dichromatism. The high degree of aggression in male S. u. consobrinus may be selectively advantageous because of (1) low density increasing space between females, (2) low density reducing selection against a relatively high frequency of violent fighting, and (3) high predation favouring lizards that do not leave their sites upon intrusion of another male. High aggression in female S. u. tristichus may be selectively advantageous because of (1) higher density leading to reduced food supply and fewer egglaying sites, and (2) lower predation reducing selection against mobility and fighting in females.
The Responsibilities of a Statistical Reviewer

CHEST, VOL. 61, NO. 5, MAY 1972 tion: preliminary report. Detroit Mich Harper Hosp Bull 9: 187-189, 1951 2 Johnson AS, Scheinherg SR. Gerisch RA, et al: Effect of cortisone on the size of experimentally produced myocardial infarcts. Circulation 7:224-228, 1953 3 Gerisch HA, Campeau L: Treatment of acute myocardial infarction in man with cortisone (abstract). Circulation 16:885, 1957 4 Gerisch HA, Campeau L: Treatment of acute myocardial infarction in man with cortisone (abstract). Am J Cardiol 1:535-536, 1958 5 Gerisch RA, Johnson AS, Anderson WL, et al: Acute myocardial infarction in man treated with cortisone. Detroit Mich Harper Hosp Bull 19:197-200, 1961 6 Chapman DW, Skaggs RH, Thomas JR, et al: The effect of cortisone in experimental myocardial infarction. Am J Med Sci 223:41-44, 1952 7 Opdyke DF, Lambert A, Stoerk HC, et al: Failure to reduce the size of experimentally produced myocardial infarcts by cortisone treatment. Circulation 8:544-548, 1953 8 Hepper NGG: The Effect of Cortisone on Healing of Experimentally Produced Myocardial Infarction in Dogs. Thesis, Mayo Graduate School of Medicine (University of Minnesota), Rochester, 1954 9 Peel AAF, Semple T, Wang I, et al: A coronary prognostic index for grading the severity of infarction. Br Heart J 24:745-760, 1962 10 DalI JLC, Peel AAF: Hydrocortisone in severe myocardial infarction and associated arrhythmias (abstract). Scott Med J 7:541, 1962 11 Dall JLC, Buchanan, J: Steroid therapy in heart-block following myocardial infarction. Lancet 2:8-12, 1962 12 Dali JLC, Peel AAF: A trial of hydrocortisone in acute myocardial infarction. Lancct 2:1097-1098, 1963 13 Scientific Subcommittee of the Scottish Society of Physicians: Hydrocortisone in severe myocardial infarction. Lancet 2:785-786, 1964 14 Semple T, Dali JLC: Steroids in myocardial infarction. Am Heart J 70:716-717, 1965 15 Lillehei RC, Longerbeani JK, Bloch JH, et al: The modern treatment of shock based on physiologic principles. Clin Pharmacol Ther 5:63-101, 1964 16 Baroody NB, Baroody WG: Adrenocorticosteroids in acute myocardial infarction. Am J Med Sci 250:402-405, 1965 17 Lusiani GB, Calzavara C, Canihari PF, et al: Valore e limiti della terapia corticosteroidea nella fase acute dell’infarto del nliocardio. C Clin Med 50:21-42, 1969 18 Barzilai D, Plavnick L, Hazani E, et al: Treatment of myocardial infarction with hydrocortisone. J lsr Med Assoc 74:165-168, 1968
Temporal oscillations in neuronal nets

A model for the interactions of cortical neurons is derived and analyzed. It is shown that small amplitude spatially inhomogeneous standing oscillations can bifurcate from the rest state. In a periodic domain, traveling wave trains exist. Stability of these patterns is discussed in terms of biological parameters. Homoclinic and heteroclinic orbits are demonstrated for the space-clamped system.
Interaction Among The Stalk Modules Of Thrombospondin-1

Thrombospondin-1 is a trimeric multi-module calcium-binding glycoprotein that is involved in important biological processes, such as angiogenesis, signal pathway, tumor formation and synaptogenesis. The subunit is composed of an N-terminal module, oligomerization module, the stalk modules, which including von Willebrand Factor type-C (vWF-C) module, three properdin or thrombospondin type 1 (TSR) modules, and three EGF-like modules, and finally the C-terminal calcium-binding wire module and the lectin-like module. Recent research indicates that conformational changes in the C-terminal modules influence ligand binding to the N-terminal modules. The second and the third EGF-like modules have been shown to interact closely with both the wire and the lectin-like modules. My work focuses on the interaction among the stalk modules and if they can propagate conformational changes between C-terminal and N-terminal elements of TSP-1 and interact with other extracellular molecules.Series of recombinant proteins have been generated based on the sequence of stalk modules. We have applied biophysical methods including far UV circular dichroism, intrinsic fluorescence, differential scanning calorimetry, isothermal titration calorimetry, and competitional ELISA. We have found there are strong interactions among the three EGF-like modules. There is one calcium binding site with in the second EGF-like module, the calcium concentration influences the stability of all the three modules from the ITC results. Based on DSC, far UV CD and fluorescence results, there are also strong interaction among the three TSRs and between TSRs and EGF-like modules. We did not find evidence for the interaction between vWF-C and TSR modules.Overall, we have demonstrated that there are strong interactions among the stalk modules of TSP-1, which help relay conformational information between the N-terminal and C-terminal parts of the protein.
Design tool chain for cyber-physical systems: lessons learned

Design automation tools evolved to support the principle of "separation of concerns" to manage engineering complexity. Accordingly, we find tool suites that are vertically integrated with limited support (even intention) for horizontal integratability (i.e. integration across disciplinary boundaries). CPS challenges these established boundaries and with this - market conditions. The question is how to facilitate reorganization and create the foundation and technologies for composable CPS design tool chains that enables reuse of existing commercial and open source tools? In this paper we describe some of the lessons learned in the design and implementation of a design automation tool suite for complex cyber-physical systems (CPS) in the vehicle domain. The tool suite followed a model- and component-based design approach to match the significant increase in design productivity experienced in several narrowly focused homogeneous domains, such as signal processing, control and aspects of electronic design. The primary challenge in the undertaking was the tremendous heterogeneity of complex cyber-physical systems (CPS), where such as vehicles has not yet been achieved. This paper describes some of the challenges addressed and solution approaches to building a comprehensive design tool suite for complex CPS.
Eleventh Hour: The Politics of Policy Initiatives in Presidential Transitions. By David M. Shafie. College Station: Texas A&M University Press, 2013. 244 pp.

Eleventh Hour: The Politics of Policy Initiatives in Presidential Transitions. By David M. Shafie. College Station: Texas A&M University Press, 2013. 244 pp. For those in the cottage industry of presidential transition studies, we wait patiently for years, anticipating a new case to devour. Deprived of a transition to examine in 2012, scholars should savor David Shafie's new book, Eleventh Hour: The Politics of Policy Initiatives in Presidential Transitions. Shafie takes on the oft-discussed but understudied activities of outgoing presidents. Specifically, he presents a series of environmental policy case studies related to late, "midnight," or "eleventh hour" rulemaking drawn from transitions in 1980-81 up to 2008-09. Shafie's writing is clear, and the book extends what we know about this important dimension of the presidency. The authority to make late decisions has long been an option for presidents, but only in the last 30 years has the practice emerged as a favored tactic for Republicans, Democrats, one-term, and two-term presidents, alike. Shafie attributes this to two familiar factors: institutionalization of domestic policy by President Richard Nixon and centralization of policy making under President Ronald Reagan. As opposed to last-minute executive orders or appointments, late rulemaking is an attractive policy strategy because rules are harder to undo by Congress and the incoming administration. It is also a preferred strategy of interest group allies of the president who appreciate the lack of public scrutiny and media attention afforded during the transition period. Despite their popularity, "midnight" regulations are routinely criticized, including by those who later use the strategy such as incoming Vice President George H. W. Bush. Bush chastised President Jimmy Carter's rulemaking during the 1980 transition. President Bush's (41) perspective is an intriguing one, as he is a participant in one role or another in all five of the transitions studied in the book. Once a critic, Bush later used the strategy during his outgoing transition in 1992-93, as did his son in 2008-09 The strengths of Shafie's book lie in these historical details and the narrative that emerges of environmental policy making since the 1970s. For example, we learn about land management policy in the Department of the Interior and in the Environmental Protection Agency through the lens of regulatory actions in the first and last few days of each administration. Policy change that was unthinkable, or at least politically untenable, for the first three and a half years in office is quickly enacted to open public lands for resource extraction or increase oil pipeline inspections, as the outgoing president celebrates a final Christmas in the White House. …
Heterotrimeric G protein beta1gamma2 subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane.

Few experimental techniques can assess the orientation of peripheral membrane proteins in their native environment. Sum Frequency Generation (SFG) vibrational spectroscopy was applied to study the formation of the complex between G protein-coupled receptor (GPCR) kinase 2 (GRK2) and heterotrimeric G protein β1γ2 subunits (Gβγ) at a lipid bilayer, without any exogenous labels. The most likely membrane orientation of the GRK2-Gβγ complex differs from that predicted from the known protein crystal structure, and positions the predicted receptor docking site of GRK2 such that it would more optimally interact with GPCRs. Gβγ also appears to change its orientation after binding to GRK2. The developed methodology is widely applicable for the study of other membrane proteins in situ.
Corn Grain Yields and Yield Stability in Four Long-Term Cropping Systems

Most long-term studies evaluate only average crop yields and overlook year-to-year yield variability, which could be highly significant. Our objectives were to evaluate the impact of long-term cropping systems and fertility management on corn (Zea mays L.) yield and yield stability. Cropping systems were (i) CC, continuous corn; (ii) CS, corn-soybean [Glycine max (L) Merr.]; (iii) 4C4A, 4 yr corn-4 yr alfalfa (Medicago sativa L.); and (iv) COW2RT, corn-oat (Avena sativa L.)/winter wheat (Triticum aestivum L.)-2 yr red clover (Trifolium pratense L.)/timothy (Pbleum pratense L.). Fertility regimes were inorganic, or manure based on crop N or P requirements. Averaged across fertility regimes, mean corn yields in 4C4A and COW2RT were 10 to 12% higher than CC, and 7% higher in 4C4A than CS. Yield trends were similar (0.28 Mg ha ―1 yr ―1 ) among all cropping systems. Coefficient of variation (CV) analysis indicated that yield variability was highest in CC (CV = 28%) and lowest in 4C4A (CV = 21%) across fertility regimes. Regression analysis indicated that response of corn yield to the environment mean did not differ among the cropping systems within inorganic and P-based manure fertility and corn yielded lower in CC than in 4C4A and COW2RT systems. Under N-based manure fertility, yield was lower in CC than in other systems in the poorest-yielding year, but similar in the highest-yielding year. Results suggest that, on average, rotations are likely to produce higher yields than CC across fertility regimes. In high-yielding years with N-based manure fertility, however, corn yield in monoculture may be similar to that in rotations.
AMBIPOLAR DIFFUSION AND DRIFT MOTIONS IN THE F2-REGION

Abstract The conditions for ambipolar diffusion in a magnetic field are discussed, and it is shown that the plasma equations of momentum-transfer yield unambiguous steady-state solutions under the conditions stated. The consistency of the solution with Maxwell's equations is discussed. It is further shown that steady-state solutions exist when an external electric field acts normally to the magnetic field lines.
A new method of radioiodine labeling of polyanionic macromolecules for radiommunoassay

A method is described for radiolabeling polyanionic macromolecules by the formation of an electrostatic complex with a radioiodinated tyramine conjugated DEAE-dextran. Data is presented on the use of this technique for the detection and quantitation of immunospecific binding of polynitrophenylated proteins, deoxyribonucleic acids, and cell surface antigens.