cssi/SciSciGPT-SciSciNet huggingface dataset:
Value of the cough pressure profile in the evaluation of patients with stress incontinence

The cough urethral pressure profile has been used to identify patients with genuine stress urinary incontinence. One hundred forty-four patients were studied to determine the value of this test in the evaluation of patients presenting with lower urinary tract symptoms. In the sitting position with a full bladder the test has a high specificity (92%) but relatively low sensitivity (41%). The clinical ramifications of using the test "cough pressure profile" and the definition "genuine stress urinary incontinence" are discussed.
ABSENCE OF HEPATIC CLEARANCE OF HAEMOPHILUS INFLUENZAE TYPE B (Hib) In RATS

In situ perfusions of livers in adult rats were performed using non-piliated (NP) & mannose-resistant piliated (MR) Hib compared to E. coli K12 NP, MR, & mannose-sensitive piliated (MS) strains. Following infusion of organisms via the portal vein, effluent was collected from the inferior vena cava during infusion of 100 ml. tissue culture medium. Total colony counts in the effluent expressed as per cent of number of organisms infused (mean values are listed where more than 1 animal was tested) were: Hib NP, 158% (3 animals); Hib MR 170% (2 animals); E. coli NP, 16% (3 animals); E. coli MR, 11% (1 animal); E. coli MS, 10% (2 animals). Similar results were obtained when whole animals (infant rats) were studied with quantitative blood cultures over a 30 min. period following IV administration of organisms. Hib MR strains recovered following in situ hepatic perfusions remained adherent to buccal epithelial cells, whereas many isolates of Hib MR strains in the live animal studies lost their pili. Adult rat livers do not effectively clear Hib NP or MR strains in this model. Further studies are needed to define the mechanisms by which Hib pili are lost or suppressed during bacteremia.
The Effects of Some Metabolites and Anoxia on the Acid-Soluble Phosphate Fraction of in Virto Rat Intestinal Strips*

Rat intestinal strips were suspended in a muscle bath containing Kreb-Henseleit solution and then were subjected to either endogenous substrate depletion and metabolite restoration or to periods of anoxia and oxygen restoration Acid-soluble phosphate determinations were performed upon the intestinal muscular is at various times during their incubation The intestinal stris were suspended upon holders which approximated the typical laboratory setup for the recording of the longitudinal muscle contractions. Substrate depletion for a period of one hour indicated a progressive decrease in the energy-rich phosphates and an increase in the inorganic phosphate. Anoxic conditions were studied, using Kreb-Henseleit solution containing glucose, 100 mg. per cent, with and without thyroxin, 10−6M. Solutions containing thyroxin appear capable of maintaining the intestinal strips more effectively.
A CASE HISTORY OF NUTRITIONAL INFORMATION ON MENUS1

This paper contains a case study of restaurant-based nutrition intervention which is but one part of the cardiovascular research and demonstration project known as the Pawtucket Heart Health Program. Pawtucket, RI, is a community of 71,204 people with a median age of about 34 years. There is a mean education level of 11 years (less than 50% of the residents are high school graduates) and the mean family income is $19,000. Nearly 44% of all people over the age of 16 are employed in manufacturing industries. It is a middle income, blue-collar city in every sense of the word. Pawtucket has a problem as well: it has one of the highest rates of heart disease in the country—that is why we were there!
The U.S. Government experience with ZBB: Some insights and observations for potential governmental units

Abstract The U.S. Government has recently completed its first year under ZBB. Their experience is serving as a catalyst for local and state governments, as well as other countries, to adopt a ZBB system. This paper describes and summarizes the government's initial experience with ZBB, providing insight into the pitfalls and problems which can be expected with the use of this technique. These findings will be of particular interest to individuals involved with the design and implementation of budget systems in various types of governmental units.
Re-ADA: reliable Ada-based descriptive architecture for C4ISR via a quantitative interoperating model

Military commands must respond to a variety of situations by quickly assembling and organizing coalition forces consisting of different components from several countries. Dependable interoperability of their C4ISR systems is vital to the success of many military applications where pressing new requirements quickly emerge and undergo rapid change.In order to achieve dependable interoperability, a reliable infrastructure is critical to incorporating operational components into C4ISR systems. Software architectures and related techniques hold the answer to interoperable, reliable and evolvable C4ISR systems. This paper analyzes the major aspects of dependable interoperability for C4ISR, and presents a Quantitative Interoperating Model (QIM) for enabling seamless interconnection, effective intercommunication and dependable interoperation between heterogeneous components over the network. Based on the QIM, an approach is synthesized toward Reliable Ada-based Descriptive Architecture (re-ADA) for C4ISR. As an executable architectural framework, re-ADA can directly be mapped into Ada95 code and constructed on the basis of CORBA to support distributed computing over-the-network. In particular, the well-formalized QIM - through mapping dependability into quantitative attributes that are attached to architectural artifacts - makes it possible to statically verify quantitative attributes during architectural design, and dynamically monitor them at runtime.
Microstructural characterization of an oriented silicalite film

The crystal orientation of a submicron silicalite membrane is examined using standard x-ray diffraction and pole-figure analyses. Results indicate that the crystals in the molecular sieving layer are preferentially oriented with both straight and sinusoidal channel networks of the zeolite parallel to the membrane surface. This requires that transport across the membrane proceed down the c-axis of the crystals which can occur by jumping between the two channel networks. EDAX data confirms that the molecular sieving layer is the pure silica zeolite silicalite.
Comparison of Stefan model with two- phase model of coal drying

Abstract The Stefan model has frequently been proposed to describe highly non-isothermal rapid drying of porous media. In particular it has been used to analyze the drying of Western coals and lignites which contain up to 40% water, almost all of which is unbound. The Stefan model may be appropriate for freezing processes but may break down when describing processes where much steam is produced within the moist porous material and flows outward because of an internally generated pressure build up. Recently, the first author developed a mechanistic moisture dynamics model called the two-phase model to remedy this deficiency and, thus, to rationally extend the drying theory. The objectives of this paper are: (1) to compare the Stefan and two-phase drying models by analyzing lignite block pyrolysis and subbituminous coal drying experiments; and (2) to determine the range of heating rates for which the Stefan model is adequate. This paper is, to our knowledge, the first to quantitatively assess the adequacy of the Stefan model to describe coal drying.
Cultivating the media activist: How critical media literacy and critical service learning can reform journalism education

The task of journalism education has been defined in relation to both the professional needs of the journalism industry and the need to educate well-informed citizens. A key part of journalism educ...
AN UNNOTED CASE OF AGREEMENT ACCORDING TO SENSE

Author's summary.—Broche, relie, etc., when following titles of books, do not agree with the titles, but according to sense with a word like livre, understood.
The exact eigenfunctions and eigenvalues of a particle in a box obtained using Gaussian wavepacket dynamics

Exact eigenfunctions for a particle in a box are obtained using Gaussian wavepacket dynamics. The eigenfunctions are obtained by propagating, without approximation, an infinite set of Gaussian wavepackets that collectively satisfy the boundary conditions of the problem, being coherent states appropriate to this problem. The method of images is applied to enforce these boundary conditions. This technique may be applied to the quantum billiard problem whenever the particle is confined to any open or closed region that tessellates space, regardless of the dimension of the region. Also, it is shown that the use of frozen Gaussians along with the De Leon-Heller spectral quantisation method gives the exact solution for the one-dimensional problem as well as for the above multi-dimensional problems, provided the components of the momentum of the wavepackets are chosen at random.
Newspaper competition and public spheres in New hampshire in the early revolutionary period

This monograph is a case study of newspaper competition in New Hampshire between the province's official newspaper and an upstart Whig challenger in the period marked by contention over the Stamp Act (1765-1766) and over the tight oligarchical reign of the Wentworth family. The case study is grounded in the civic republican tradition articulated by Bernard Bailyn and Gordon Wood as well as the revisionist scholarship since the 1960s that takes the role of the “little people” seriously. It maintains that the competition between the two newspapers contributed to, and opened up, the public spaces in Portsmouth, New Hampshire, to a wider compass than might have been predicted if one follows the standard Habermasian argument for the develop of a bourgeois public sphere. In part, these more diverse public spheres grew out of a staple of ritualized communication in the form of effigy demonstration reports and stamp master resignation speeches at both the local and intercolonial levels. The paper traces the prove...
ASSAY OF IODINE CONTENT OF THYROID EXTRACT BY X-RAY ABSORPTION EDGE ANALYSIS.

The assay of thyroid extract for iodine content by the X-ray absorption edge technique has been investigated. The method has been found to be applicable to the crude, U.S.P. powder, and uncoated Enseals. Excellent precision has been found for the assay of crude thyroid extract. It is also shown that because of the nature of the method the determination is specific for iodine. The instrumentation used is the same as that used for X-ray crystallography by the diffractometer method.
Safeguarding Abila: Spatio-temporal activity modeling VAST 2014 Mini Challenge 2 award: Honorable mention for effective presentation

We introduce a system for visual analysis of GPS tracking and financial data. This system was developed in response to VAST Mini-Challenge 2 and comprises of different interfaces for mining spatio-temporal and financial data.
Visualizing International Relations: Assessing Student Learning Through Film

Much has been written in the last decade on using film as a pedagogical tool in the classroom and specifically in the teaching and learning of international relations (IR). Instructors assert that film has numerous beneficial effects in terms of student interest, engagement, conceptual understanding, and class performance. This article builds upon the existing literature and fills a gap by presenting and analyzing the empirical findings of recent classroom research on the usefulness of five films for student engagement, understanding, and interpretation of various IR topics (IR theory, media and war, and human rights). The data and their analysis reveal that film can potentially be a powerful and dramatic medium to aid student learning of IR, but the results are mixed. Students' written work also demonstrates that film's value can be overrated and that film can be superficial and confusing. This research sheds light on how we can better use film in the international studies classroom beyond its entertainment and illustrative value.
Influence of saturated and unsaturated fats on platelet fatty acids in cholesterol-fed rabbits

Feeding natural fats varying in contents of palmitate (16:0), stearate (18:0), oleate (18:1), and linoleate (18:2) to rabbits resulted in modulation of platelet phospholipid fatty acyl composition. Rabbits were fed high fat semipurified diets containing 2% corn oil (CO) + 18% CO, cocoa butter (CB) or milkfat (M) for periods of up to 300 d. Platelet phospholipid linoleate contents corresponded to diet levels with 18:2 highest in CO-fed rabbits and following the sequence CO greater than CB greater than M. Stearate was highest in CB-fed rabbits, corresponding to high 18:0 levels in CB, but palmitate levels were not affected by diet. Both CB and M-fed rabbits were higher than CO-fed rabbits in oleate. Though CO is highest in 18:2, the accepted 20:4 precursor, arachidonate was highest in M-fed rabbits. Adding cholesterol (0.2%) to the diets did not affect platelet phospholipid fatty acyl composition except to elevate 20:4 in M-fed rabbits. CO-fed rabbits showed uniquely high levels of tetracosadienoate (24:2). Fatty acyl composition data were essentially constant between 200 and 300 d on diet. Phospholipid fatty acyl unsaturation was apparently homeostatically controlled as mole percent unsaturate to saturate ratios were independent of diet. The observed homeostasis resulted in minimal diet influences on platelet membrane fluidity and ADP or collagen stimulated platelet aggregation. Platelet fluidity, determined by fluorescence polarization, was a function of oleate and linoleate contents of the cells. Cholesterol feeding generally lowered platelet fluidity and altered the dependence of fluidity on fatty acyl composition.
Non-TMR SEU-Hardening Techniques for SiGe HBT Shift Registers and Clock Buffers

We report new results from both broad-beam, heavy-ion and proton experiments for circuit-level RHBD techniques in SiGe digital logic. Redundant circuit elements within the latches are used to significantly reduce single-event upset rates in shift registers and clock paths, without resorting to TMR techniques.
Soil microbial community composition and structure: residual effects of contrasting N fertilization of swine lagoon effluent versus ammonium nitrate

Land application of swine lagoon effluent (SLE) often changes soil pH and the concentrations of nutrients and trace metals. We hypothesize that fertilization-associated alteration in soil properties would have long-lasting effects on soil microbial community and the effects would depend on fertilization rates. In this study, microbial community composition and structure were characterized with phospholipid fatty acid (PLFA) profiles. Soils (0–7.5 cm depth) were sampled in March 2004 from the field plots planted with bermudagrass and tall fescue that received 0–600 kg plant available N (PAN) ha−1 year−1 of SLE or ammonium nitrate (AN) from 1999 to 2001. We observed that PLFA profiles differed significantly (P < 0.05) between soils supplied with SLE versus AN, specifically at the highest application rate. PLFA profiles were strongly correlated with fertilization-associated changes in soil pH (Pearson’s correlation coefficient r = 0.80, P < 0.01) and Mehlich III extractable Ca (r = 0.78, P < 0.01) and Mg (r = 0.72, P < 0.01). In soils receiving 200 and 400 kg PAN ha−1 year−1 of SLE or AN, microbial community was enriched slightly with fungi (P < 0.01). In soils receiving 600 kg PAN ha−1 year−1 of SLE or AN, however, microbial community was stressed as evidenced by the reduction in microbial monounsaturated fatty acids and by the increase in the ratios of saturated-to-unsaturated fatty acids and of cyclopropyl fatty acids-to-their monoenoic precursors. These changes in PLFA biomarkers for stress were significantly (P < 0.01) correlated with soil pH and Mehlich III extractable Ca and Mg, but not with soil properties such as total soil C, soluble soil organic C, soil inorganic N or Mehlich III extractable soil P. Our results indicated that soil microbial community was negatively affected when soils received SLE at an application rate of 600 kg PAN ha−1 year−1 in this forage production system.
Overview of Cell-Free Protein Synthesis: Historic Landmarks, Commercial Systems, and Expanding Applications

During the early days of molecular biology, cell-free protein synthesis played an essential role in deciphering the genetic code and contributed to our understanding of translation of protein from messenger RNA. Owing to several decades of major and incremental improvements, modern cell-free systems have achieved higher protein synthesis yields at lower production costs. Commercial cell-free systems are now available from a variety of material sources, ranging from "traditional" E. coli, rabbit reticulocyte lysate, and wheat germ extracts, to recent insect and human cell extracts, to defined systems reconstituted from purified recombinant components. Although each cell-free system has certain advantages and disadvantages, the diversity of the cell-free systems allows in vitro synthesis of a wide range of proteins for a variety of downstream applications. In the post-genomic era, cell-free protein synthesis has rapidly become the preferred approach for high-throughput functional and structural studies of proteins and a versatile tool for in vitro protein evolution and synthetic biology. This unit provides a brief history of cell-free protein synthesis and describes key advances in modern cell-free systems, practical differences between widely used commercial cell-free systems, and applications of this important technology.
Preferences, Structure and Influence: The Engineering of Consent

I present a decision process framework that informs the design and implementation of stakeholder influence strategy. This process combines insights from agent-based dynamic utility and dynamic network processes. Stakeholders strategically seek an outcome as close as possible to their preferred point but also wish to be on the winning side and not to pursue positions divergent from stakeholders with whom they have strong affective ties. Simulation analysis highlights important effects from embedding stakeholders within such an interdependent policymaking network. The resulting decision process framework can be used by firms to assess the likely dynamics within such a stakeholder network as well as to compare alternative treatments to that network for their efficacy in securing a favorable policy outcome, collective decision, or shift in group opinion.
Theory and practice of sequential machine testing and testability

Undetectable and redundant faults in synchronous sequential circuits have recently received wide attention. Previous classifications of detectable, undetectable and redundant faults in such circuits assume certain restrictions regarding the operation of the circuit-under-test. In this work, no restrictions are imposed, and faults are classified on the basis of the existence (or lack) of an input/output experiment that distinguishes the fault free and faulty circuits. It is shown that faults that were previously considered redundant are detectable according to the new definitions (detectable in a probabilistic sense). The practical usefulness of the fault classification presented is discussed.
The Role of Ocean–Atmosphere Coupling in the Zonal-Mean Atmospheric Response to Arctic Sea Ice Loss

AbstractThe role of ocean–atmosphere coupling in the zonal-mean climate response to projected late twenty-first-century Arctic sea ice loss is investigated using Community Climate System Model version 4 (CCSM4) at 1° spatial resolution. Parallel experiments with different ocean model configurations (full-depth, slab, and no interactive ocean) allow the roles of dynamical and thermodynamic ocean feedbacks to be isolated. In the absence of ocean coupling, the atmospheric response to Arctic sea ice loss is confined to north of 30°N, consisting of a weakening and equatorward shift of the westerlies accompanied by lower tropospheric warming and enhanced precipitation at high latitudes. With ocean feedbacks, the response expands to cover the whole globe and exhibits a high degree of equatorial symmetry: the entire troposphere warms, the global hydrological cycle strengthens, and the intertropical convergence zones shift equatorward. Ocean dynamics are fundamental to producing this equatorially symmetric pattern...
Predictors of Intention to Eat 2.5 Cups of Vegetables among Ninth-Grade Students Attending Public High Schools in Eastern North Carolina.

Abstract Objective To identify beliefs about eating 2.5 cups of vegetables and to assess how well these beliefs predict intention to eat them. Design A survey based on the Theory of Planned Behavior. Setting Two public high schools in 2 counties in eastern North Carolina. Participants 157 ninth-grade students (mean age = 14.71 years [SD = 0.82]). Analysis Regression analysis was performed to assess how well the variables of the Theory of Planned Behavior predicted behavioral intention to eat 2.5 cups of vegetables. Findings Attitude, subjective norms, and perceived behavioral control predicted 77.2% of variance of intention to eat 2.5 cups of vegetables (F [3, 154] = 178.05, P P P P Conclusions and Implications Factors such as impact of parents and peers, availability of vegetables at home and in school, and making sure that vegetables offered to teens are tasty are important in increasing their intention to eat the recommended amount of vegetables. These factors could help education campaigns targeted toward teens be more successful.
Environmental and chemical sensing applications of diode and quantum cascade laser based gas sensors

Summary form only given. In recent years, laser-based techniques for the real time detection of trace gases with ultra high sensitivity and excellent selectivity have been developed. In this paper, we report the development of portable automated gas sensors based on three different types of device architectures. If the anticipated concentration levels of a desired trace gas are sufficiently large and if this species exhibits near IR resolved rotational-vibrational transitions that are free of interfering species (such as CO/sub 2/ and H/sub 2/O), then a sensor based on distributed feedback (DFB) diode lasers are ideally suited. If, however, trace gas detection at ppb and ppt levels is required for a specific application, it is convenient to select a sensor architecture suitable for the mid-IR based on difference-frequency generation (DFG) of two diode lasers in a nonlinear optical material such as periodically poled lithium niobate or quantum cascade-DFB lasers in the 3 to 5 /spl mu/m and 4 to 17 /spl mu/m spectral region, respectively. In the case of the two types of diode laser DFG based gas sensors, we have used robust fiber pigtailed telecommunications DFB diode lasers and, when appropriate, Yb and Er/Yb optical fiber amplifiers to boost their power and fibered beam delivery. The QC-DFB based gas sensors have so far been operated either CW or pulsed, cooled to liquid nitrogen and room temperatures, respectively. Details of the spectroscopic parameters for the three spectroscopic devices will be reported, specifically their available power, linewidth, and wavelength tunability.
AN APPRAISAL OF CHILD PSYCHIATRY IN A COMMUNITY HEALTH PROJECT: Relevance as a Function of Social Context

The past several years have witnessed nationwide changes in delivery of health services (Jahoda, 1958; Caplan, 1964; English, 1968). Child psychiatry has mqved along with other specialties from clinics, hospitals, and privaje offices into open systems of community psychiatry (Malone, 1967; Bolman, 1967). Time-honored practices often have been received as foreign or deviant in these unaccustomed settings, but services, nevertheless, are usually relevant, sometimes desperately needed (Harrison et al., 1965; Christmas, 1969). Acceptance in these circumstances depends on certain critical factors seen in social context and such controversial items as age, class, ethnicity, and race arouse dramatically different responses depending on context. Sociological theory becomes essential to understanding program development and estimating chances for success; ideas about groups are particularly helpful. Sociologists categorize groups as primary, secondary, and tertiary. Primary groups are small and intimate. They focus on personal matters such as family problems and joys. People relate in primary groups on a frequent and regular basis (Cooley, 1909). Secondary groups are larger and less intimate. They also meet regularly, but focus on such functional matters as school, job, and clubs (Burgess,
Introduction: The Three and a Half Minute Transaction: Boilerplate and the Limits of Contract Design

The Hofstra Law Review has organized an “Ideas” symposium around our book manuscript “The Three and a Half Minute Transaction” (see http://ssrn.com/abstract=1937900). The idea for this symposium came from a debate that occurred at a faculty workshop at the Hofstra Law School some months ago where we were presenting our book manuscript. The topics of conversation included the following: the future of the current big-law-firm model, what value lawyers add in commercial transactions that use boilerplate contracts, why (and whether) boilerplate contracts are so slow to change, why law firms do not generally have R&D departments, the resolution of the Eurozone sovereign debt crisis and more. The Essays in this symposium are from an exceptional group of scholars and practitioners and we are honored that they use our manuscript as their jumping off point to tackle some of the topics mentioned. What we provide here is a brief introduction to the manuscript itself.
Early Treatment Response in Children and Adolescents Receiving CBT for Trauma

Objectives To investigate the incidence and correlates of early treatment response among youth receiving cognitive behavioral therapy (CBT) for posttraumatic stress disorder (PTSD). Methods 56 youth who participated in a randomized controlled trial of CBT for PTSD and D-cycloserine were included. Youth with PTSD symptoms below clinical cutoff after Session 4 of a 12-session protocol were classified as early treatment responders (32% of parent reports, 44.6% of child reports). Pretreatment characteristics were examined in relation to responder status. Results Lower levels of pretreatment PTSD, depression, and anxiety symptoms and fewer trauma types were related to child- and parent-reported responder status (d = .57, d = .52, respectively). Early treatment response was maintained at follow-up. Conclusions Pretreatment symptoms levels and number of traumas may play an important role in predicting early treatment response. Correlates of early treatment response may provide avenues for identifying youth who could benefit from abbreviated protocols.
Assessment of Three-class Diagnostic Tests when Disease Verification is Subject to Selection

In the assessment of a three-class diagnostic test, the receiver operating characteristic surface has been one of the established tools when subsequent definitive disease verification can be obtained. However, omitting cases that have no definitive verification can seriously bias the assessment. In this paper, the assumption about the selection mechanism for verification is made in order to adjust for the bias. Through sets of numerical simulations with differential selection mechanisms, the properties of adjusted estimates are demonstrated. The proposed method is used to evaluate the accuracy of using Mini-Mental State Examination in diagnosing the three disease states of Alzheimer's disease.
Successful Management with Glue Injection of Arterial Rupture Seen during Embolization of an Arteriovenous Malformation Using a Flow-Directed Catheter: A Case Report

We present a case in which an arterial rupture occurring during embolization of an arteriovenous malformation of the left occipital lobe with a flow-directed microcatheter, was successfully sealed with a small amount of glue. We navigated a 1.8-Fr Magic catheter through the posterior cerebral artery, and during superselective test injection, extravasation was observed at the parieto-occipital branch. The catheter was not removed and the perforation site was successfully sealed with a small amount of glue injected through the same catheter. Prompt recognition and closure of the perforation site is essential for good prognosis.
A probabilistic approach for automated discovery of perturbed genes using expression data from microarray or RNA-Seq

BackgroundIn complex diseases, alterations of multiple molecular and cellular components in response to perturbations are indicative of disease physiology. While expression level of genes from high-throughput analysis can vary among patients, the common path among disease progression suggests that the underlying cellular sub-processes involving associated genes follow similar fates. Motivated by the interconnected nature of sub-processes, we have developed an automated methodology that combines ideas from biological networks, statistical models, and game theory, to probe connected cellular processes. The core concept in our approach uses probability of change (POC) to indicate the probability that a gene's expression level has changed between two conditions. POC facilitates the definition of change at the neighborhood, pathway, and network levels and enables evaluation of the influence of diseases on the expression. The 'connected' disease-related genes (DRG) identified display coherent and concomitant differential expression levels along paths. ResultsRNA-Seq and microarray breast cancer subtyping expression data sets were used to identify DRG between subtypes. A machine-learning algorithm was trained for subtype discrimination using the DRG, and the training yielded a set of biomarkers. The discriminative power of the biomarkers was tested using an unseen data set. Biomarkers identified overlaps with disease-specific identified genes, and we were able to classify disease subtypes with 100% and 80% agreement with PAM50, for microarray and RNA-Seq data set respectively. ConclusionsWe present an automated probabilistic approach that offers unbiased and reproducible results, thus complementing existing methods in DRG and biomarker discovery for complex diseases. Automated analysis of high throughput data for disease gene and biomarker discovery.Network based analysis using probability of change for gene expression.Analysis of coherent path level changes in regulation in response to complex disease.Biomarkers with high precision and accuracy of classification.
Primary gynecological neoplasms and clinical outcomes in patients diagnosed with breast carcinoma.

The purpose of this study was to quantify and describe nonmammary neoplasms (n-MN), particularly gynecological neoplasms, in a patient population previously diagnosed with breast cancer. Data were collected prospectively in our institutional review board–approved registry for patients diagnosed with infiltrating breast cancer or ductal carcinoma in situ. Patients who developed a second, n-MN were identified; neoplastic site, time to development after breast cancer, and clinical outcomes were recorded. FIGO stage was recorded for patients who developed a gynecological neoplasm. Synchronous bilateral breast cancer was defined as a second, contralateral diagnosis made within 12 months of the first and, similarly, synchronous n-MN were defined as those identified within 1 year of a breast cancer diagnosis. Outcome curves were generated using the method of Kaplan and Meier, and compared using the log-rank test. Of 4126 patients diagnosed with breast cancer, 3% developed a n-MN, the majority of which were nongynecological and asynchronous to the initial breast cancer diagnosis. Three percent of patients diagnosed with breast cancer were diagnosed with a second, n-MN. Among patients who developed a n-MN, most developed a nongynecological cancer more than 1 year after the initial breast cancer diagnosis, and their outcomes were significantly worse than those patients who did not develop a n-MN.
Human Resource Management: The Right Hand of Strategy Implementation

There has been a growing recognition that human resource management can, or at least should, play an important role in the development and implementation of effective strategic plans. This paper suggests that it is in strategy implementation where human resource management may be able to play its most significant role. A continuum of HR roles is described. Specific human resource elements that strategists should incorporate in their thinking about strategy implementation are discussed.
Budget-Constrained Knowledge in Multiagent Systems

The paper introduces a modal logical system for reasoning about knowledge in which information available to agents might be constrained by the available budget. Although the system lacks an equivalent of the standard Negative Introspection axiom from epistemic logic S5, it is proven to be sound and complete with respect to an S5-like Kripke semantics.
The Influence of Debris on Rolling Bearing Performance: Identifying the Relevant Factors

Influence de la contamination par particules solides sur les performances d'un palier de roulement. Recherche des parametres determinants
Coupled-inductor analysis and design

A new coupled-inductor multiple air-gap structure is proposed and analyzed. These EI and EE core configurations eliminate many of the problems associated with the earlier single air-gap structures such as: high sensitivity of ripple currents to air-gap and/or turns ratio changes, complex winding arrangements and consequent high costs and inferior thermal characteristics. To facilitate the design, critical leakage parameter I is evaluated for a whole line of EI and EE cores.
Robust multi-object tracking using confident detections and safe tracklets

This paper presents a novel approach to simultaneous tracking of multiple targets in a video. Instead of using the unreliable “detector confidence scores,” it develops a new scoring system, ConfRank, that originates from the PageRank idea where not only the detection confidence score, but that the quality and the quantity of adjacent detections in spatio-temporal neighborhood are considered. The new scoring system effectively separates False Positives from True Positives, that enables us to remove unwanted detections using a simple threshold without loosing targets. Our framework outperforms state-of-the-art tracking methods in most evaluations. Specifically, it significantly reduces False Positives and switch identities while keeping missed detections low leading to higher precision and multiple object tracking accuracy (MOTA) on several standard datasets.
Histology Grade Is Independently Associated With Relapse Risk in Patients With Ulcerative Colitis in Clinical Remission: A Prospective Study.

Histology Grade Is Independently Associated With Relapse Risk in Patients With Ulcerative Colitis in Clinical Remission: A Prospective Study
High-Fidelity Simulations and Low-Order Modeling of a Rapidly Pitching Plate

numerical simulations at Reynolds number 1000 and a low-order inviscid point vortex model. The pitching rate and axis position are systematically varied, and their eect on the generated aerodynamic forces is inspected. It is found that the maximum lift and drag developed during the pitch-up both increase nearly linearly with increasing pitch rate, though the rates of increase diminish as the pitching axis is moved aft. Furthermore, the maximum lift-to-drag ratio tends to saturate with increasing pitch rate, with the asymptotic value decreasing as the axis is moved aft. The forces predicted by the low-order inviscid Brown{Michael model are compared with the high-delity results. Good qualitative agreement is achieved, though the point vortex model tends to over-predict both components of force. The lift force obtained from the model is decomposed into inertial reaction and circulatory components, and their relative contributions are inspected.
Morphology Control, Dopant Incorporation, and Selective Epitaxial Growth of 4H-SiC at Low Temperatures Using CH3Cl Growth Precursor

Low-temperature homoepitaxial growth of 4H-SiC using halo-carbon precursors was further investigated to address the problems limiting increase of the growth rate of the defect-free epilayers at growth temperatures below 1300°C. Enhanced etching of Si clusters in the gas phase was achieved by adding HCl during the low-temperature growth. The effective Si/C ratio above the growth surface was increased as a result of reduced depletion of silicon vapor species by cluster condensation, which resulted in drastically improved epilayer morphology and significant increase of the growth rate. Intentional insitu nitrogen doping of epitaxial layers during 1300°C growth on Si and C faces revealed more than order of magnitude higher nitrogen donor incorporation in the C-face epitaxial layers. Finally, a feasibility of selective epitaxial growth using low-temperature masking materials such as SiO2 was demonstrated.
41. Case report: telangiectatic osteosarcoma of the left humerus in a 13 year old Girl

Telangiectatic osteosarcoma is a rare variant, representing around 3% of osteosarcomas overall. The main differential radiographi-cally, grossly and on histology is with aneurysmal bone cyst and both these lesions tend to occur in the metaphysis of long bones with a peak incidence in the 2ns decade. We present the case of a 13-year-old girl who attended the Women’s and Children’s Hospital, Adelaide with left upper arm pain for 4 weeks after a fall in 2012. An X-ray showed a lytic destructive lesion of the proximal left humerus while magnetic resonance imaging revealed features highly suggestive of telangiectatic osteosarcoma. The lesion was biopsied which confirmed osteosarcoma, with difficulty subtyping due to the limited material available. After two cycles of chemotherapy the patient underwent a limb salvage operation. The specimen was sent to pathology where histology confirmed the diagnosis of telangiectatic osteosarcoma. We review and discuss the clinical, imaging, and pathological features of this rare variant of osteosarcoma.
Monitoring on Hygiene Indices of Rural Area Drinking Water in Rizhao City,2009-2012

[Objective]To understand the hygienic status of rural drinking water in Rizhao city,and to provide basis for further improvement of rural area drinking water hygiene management.[Methods]Drinking water supply projects in the rural area of Rizhao city were selected randomly and the samples of finished water and tap water were tested both in flooding and dry seasons.[Results]From 2009 to 2012,946 water samples were collected and the total qualified rate was 59.30%.The qualified rates were 36.36%,38.24%,68.30%,and 68.37% for selected years respectively.The difference in qualified rates among the four testing years were statistically significant(χ2=46.58,P0.0001); the qualified rates of water samples in the dry season was higher than those in the flooding season(χ2=12.12,P=0.0005); the qualified rates of the finished water samples were higher than those of the tap water samples(χ2=33.15,P0.0001).[Conclusion]The most important problem of rural drinking water is unqualified microorganism index.Some unqualified physical and chemical indices also need to be addressed.
The effect of ligation or separation between the intrauterine device horn and adjacent ovary on implantation in the hamster

The purpose of this study was to determine whether the luteolytic action of an intrauterine device (IUD) is suppressed following interruption of the continuity between the IUD uterine horn and the adjacent ovary. After several estrous cycles, a silk IUD was placed in the cervical end of one uterine horn of adult hamsters. The animals were then mated, and on day 6 of gestation the ovary and oviduct contralateral to the IUD were removed and a ligature was placed between the IUD horn and the adjacent ovary. The hamsters were killed on day 9 or day 13 of gestation. Fetal development in the contralateral horn was suppressed on day 13 but not on day 9. In the second study the animals were treated as in the first study except that the communication between the IUD horn and the adjacent ovary was severed completely. The hamsters were killed on day 9 or day 13. On both days 9 and 13 normal fetal development was observed in the control horn; no implantation sites were present in the IUD side. In the control (non-IUD) animals of each study, normal fetuses were present in both uterine horns. The study demonstrates that luteolysis does not occur if there is complete disruption of the communication between the IUD horn and ovary. The study also demonstrates that, since implantation did not occur in the IUD horn with a normally functioning ipsilateral ovary, the luteolytic action of the device is not the prime factor in suppressing implantation in the hamster.
Enzyme-catalyzed expressed protein ligation

Expressed protein ligation is a valuable method for protein semisynthesis that involves the reaction of recombinant protein C-terminal thioesters with N-terminal cysteine (N-Cys)-containing peptides, but the requirement of a Cys residue at the ligation junction can limit the utility of this method. Here we employ subtiligase variants to efficiently ligate Cys-free peptides to protein thioesters. Using this method, we have more accurately determined the effect of C-terminal phosphorylation on the tumor suppressor protein PTEN.
Offering Multiple Entry-Points into STEM for Young People

Enrollment in the STEM fields (science, technology, engineering and math) is not keeping pace with the need. Recent reports indicate a decrease in the number of graduates from STEM fields and a shortage on the job market. Considering these issues, particular attention has been paid developing innovative methods and tools for improved teaching of STEM themes. This work presents an approach involving multiple entry points for young people to engage in the STEM fields. This approach is manifested in the non-profit association Practical Robotics Institute Austria (PRIA) with its activities designed to fill STEM gaps in the Austrian education system and to bring innovative engagement that cannot be found in the classrooms. Thus, STEM literacy is fostered as well as the development of systems thinking, problem solving, and teamwork skills.
Thermal Swing Adsorption: Regeneration, Cyclic Behavior, and Optimization

Adsorption processes are generally operated in a cyclic manner. Broad classes of cycles are named after the regeneration method. Thermal swing adsorption is based on regeneration by raising the temperature of the adsorbent and purging. Pressure swing adsorption involves regeneration by reducing the total pressure in the bed and usually purging. Pressure-swing adsorption is favored for adsorbates of fairly high volatility, while thermal-swing adsorption is best for adsorbates of moderate volatility. For adsorbates of very low volatility, the adsorbent is replaced rather than regenerated in place, with spent adsorbent possibly reactivated in a furnace.
Bilateral Tensor Fasciae Suralis Muscles in a Cadaver with Unilateral Accessory Flexor Digitorum Longus Muscle

Muscle variants are routinely encountered in the dissection laboratory and in clinical practice and therefore anatomists and clinicians need to be aware of their existence. Here we describe two different accessory muscles identified while performing educational dissection of a 51-year-old male cadaver. Tensor fasciae suralis, a rare muscle variant, was identified bilaterally and accessory flexor digitorum longus, a more common muscle variant, was present unilaterally. Tensor fasciae suralis and accessory flexor digitorum longus are clinically relevant muscle variants. To our knowledge, the coexistence of tensor fasciae suralis and accessory flexor digitorum longus in the same individual has not been reported in either cadaveric or imaging studies.
Differential deposition of H2A.Z in rice seedling tissue during the day-night cycle

Chromatin structure has an important role in modulating gene expression. The incorporation of histone variants into the nucleosome leads to important changes in the chromatin structure. The histone variant H2A.Z is highly conserved between different species of fungi, animals, and plants. However, dynamic changes to H2A.Z in rice have not been reported during the day-night cycle. In this study, we generated genome wide maps of H2A.Z for day and night time in harvested seedling tissues by combining chromatin immunoprecipitation and high-throughput sequencing. The analysis results for the H2A.Z data sets detected 7099 genes with higher depositions of H2A.Z in seedling tissues harvested at night compared with seedling tissues harvested during the day, whereas 4597 genes had higher H2A.Z depositions in seedlings harvested during the day. The gene expression profiles data suggested that H2A.Z probably negatively regulated gene expression during the day-night cycle and was involved in many important biologic processes. In general, our results indicated that H2A.Z may play an important role in plant responses to the diurnal oscillation process.
Measuring Self-Reported Discrimination: Trends in Question Wording Used in Publicly Accessible Datasets:

Research on Americans’ self-reported experiences of discrimination or unfair treatment (hereafter collectively referred to as differential treatment) has proliferated since the 1960s. Despite the growth of this research, some health scholars express concern about how to effectively measure self-reported experiences of differential treatment. Specifically, it has been suggested that the term discrimination is emotionally charged and that more neutral terms, such as unfair treatment, should be used instead. This study documents trends in question wording used to capture self-reported differential treatment in publicly accessible U.S. health and social science surveys. Our systematic review of 221 publicly available surveys reveals that there was a slight decline in social scientists’ use of the once dominant term discrimination. Yet, there has been no consensus in question wording in health surveys, as health scholars increasingly use discrimination, unfair treatment, or other (e.g., because you are) or mul...
Benchmark Comparison for a Multi-Processing Ion Mobility Calculator in the Free Molecular Regime

A benchmark comparison between two ion mobility and collision cross-section (CCS) calculators, MOBCAL and IMoS, is presented here as a standard to test the efficiency and performance of both programs. Utilizing 47 organic ions, results are in excellent agreement between IMoS and MOBCAL in He and N2, when both programs use identical input parameters. Due to a more efficiently written algorithm and to its parallelization, IMoS is able to calculate the same CCS (within 1%) with a speed around two orders of magnitude faster than its MOBCAL counterpart when seven cores are used. Due to the high computational cost of MOBCAL in N2, reaching tens of thousands of seconds even for small ions, the comparison between IMoS and MOBCAL is stopped at 70 atoms. Large biomolecules (>10000 atoms) remain computationally expensive when IMoS is used in N2 (even when employing 16 cores). Approximations such as diffuse trajectory methods (DHSS, TDHSS) with and without partial charges and projected area approximation corrections can be used to reduce the total computational time by several folds without hurting the accuracy of the solution. These latter methods can in principle be used with coarse-grained model structures and should yield acceptable CCS results.
Aerodynamic comparisons of flexible membrane micro air vehicle wings with cambered and flat frames

Flexible membrane wings at the micro air vehicle scale can experience improved lift/drag ratios, delays in stall, and decreased time-averaged flow separation when compared to rigid wings. This rese...
Other Mechanisms for Achieving Gene Duplication

The following are mechanisms other than those previously mentioned which could conceivably contribute to the creation of genetic redundancy, although, to date, there exists no evidence to suggest that these means were actually employed during the evolution of vertebrates.