cssi/SciSciGPT-SciSciNet huggingface dataset:
Absent right and persistent left superior vena cava without other congenital anomaly: A rare combination diagnosed by transesophageal echocardiography

A 70-year-old man with a history of anorexia, weight loss, and progressive shortness of breath was studied by transesophageal echocardiography. In addition to a mass occupying the right ventricular outflow tract, a rare congenital heart anomaly was discovered serendipitously: persistent left superior vena cava, absent right superior vena cava, and no other congenital abnormality. The echocardiographic findings were confirmed by computed tomographic scanning and later during heart surgery performed to resect the malignant tumor.
Fluorinated poly(arylene ether ketone)s bearing pentafluorostyrene moieties prepared by a modified polycondensation

The polycondensation of decafluorobenzophenone with hexafluorobisphenol A was modified by the addition of a molecular sieve dehydrating apparatus to the refluxing reaction system. This modification promoted the polymerization and enabled the reactions to be conducted in milder conditions and completed in a shorter time, thereby depressing side reactions such as branching and crosslinking. The resulting fluorinated poly(arylene ether ketone)s (FPAEK) were free of gel particles and possessed the designed molecular weights. This modified procedure was also suitable for introducing crosslinkable pentafluorostyrene (FSt) moieties into the polymers at the chain ends and/or inside the chain with the vinyl group of FSt being pendant. The resulting FSt containing fluorinated poly(arylene ether ketone)s (FPAEK-FSt) can then be thermally crosslinked at 100 °C in the presence of 1% benzoyl peroxide (BPO) or at 250 °C without any initiator. The glass-transition temperatures (T g 's) of FPAEK increased with increasing molecular weight and leveled off at about 147 °C for the polymer with a number-average molecular weight of 18,600 Da, whereas the values were not apparently affected by the addition of FSt units. However, crosslinking of the FPAEK-FSt resulted in an approximate 30 °C increase of the T g . Spin-coating FPAEK-FSt onto silicon wafers followed by crosslinking gave films with excellent thermal stability, physical strength, and adhesion to the substrate as well as good reproducibility in terms of film preparation and optical properties. The refractive index and birefringence of the films measured at a wavelength of 1.55 μm were 1.502 and 2.5 X 10 -3 , respectively.
Attitudes and barriers towards participation in an acupuncture trial among breast cancer patients: a survey study

As breast cancer patients increasingly use complementary and alternative medicine (CAM), clinical trials are needed to guide appropriate clinical use. We sought to identify socio-demographic, clinical and psychological factors related to willingness to participate (WTP) and to determine barriers to participation in an acupuncture clinical trial among breast cancer patients. We conducted a cross-sectional survey study among post-menopausal women with stage I-III breast cancer on aromatase inhibitors at an urban academic cancer center. Of the 300 participants (92% response rate), 148 (49.8%) reported WTP in an acupuncture clinical trial. Higher education (p = 0.001), increased acupuncture expectancy (p < 0.001), and previous radiation therapy (p = 0.004) were significantly associated with WTP. Travel difficulty (p = 0.002), concern with experimentation (p = 0.013), and lack of interest in acupuncture (p < 0.001) were significant barriers to WTP. Barriers differed significantly by socio-demographic factors with white people more likely to endorse travel difficulty (p = 0.018) and non-white people more likely to report concern with experimentation (p = 0.024). Older patients and those with lower education were more likely to report concern with experimentation and lack of interest in acupuncture (p < 0.05). Although nearly half of the respondents reported WTP, significant barriers to participation exist and differ among subgroups. Research addressing these barriers is needed to ensure effective accrual and improve the representation of individuals from diverse backgrounds.
Ethnoarchaeology: Current Research and Field Methods

This book is the proceedings of a conference on ethnoarchaeology held in Rome in May 2010, with particularly strong representation of researchers from Italy, Spain, France, and Greece. Like many co...
André Gide's collection offaits divers

Andre Gide's collection offaits divers spans a period of fifty years and includes more than 650 documents. A database analysis offers an efficient means of handling such extensive material. Our goal is to trace statistically this author's varied interests as they evolved throughout his career.
Should enteral nutrition be started in the first week of critical illness

Purpose of review To review the mechanistic evidence for early enteral nutrition in critically ill patients within the first week of ICU admission. Recent findings There is a lack of recent large randomized controlled trials showing clinically important outcome benefits related to early enteral nutrition. Most supporting studies are based on the animal models, and explore mechanisms of benefit related to gut immunity and oxidative stress. In addition, the impact of nutrient deprivation on the microbiome recently shown in a human trial is compelling. Large randomized controlled clinical trials have emerged in the last 2 years, however, comparing minimal enteral nutrition therapy and enteral nutrition versus parenteral nutrition. They call into question the low quality of clinical evidence and the widespread support for early enteral nutrition as a primary recommendation. As a result, the questions of whether or not enteral nutrition should be initiated in the first week versus standard of care or parenteral nutrition and how clinicians justify this recommendation are raised. Summary Despite the wide range of quality in the current clinical outcomes evidence, early enteral nutrition within the first week of ICU admission, delivered to the appropriate patient, promotes gut-mediated immunity, lowers metabolic response to stress, maintains microbial diversity, and improves clinical outcomes versus standard of care or parenteral nutrition therapy.
Quantitative STEM and HRTEM Studies on Au Metallic Nano-Catalysts

Indium antimony (InSb) has been deformed in compression under gaseous confining pressure (Paterson apparatus) above and below the brittle to ductile transition occurring around 150°C. Thin foils have been prepared from the deformed samples and dislocations were characterized with conventional TEM as well as LACBED. This paper focuses on the room temperature deformation microstructures which appeared to be extremely complex with the observation of very well arranged network of perfect and partial dislocations. In such case, the traditional dislocation extinction conditions were extremely difficult to apply and only the use of the LACBED technique uncovered the nature of the observed dislocations and gave further insight to their interactions, revealing in particular the presence of partial dislocation dipoles. These original observations suggest a change of deformation mechanism at the brittle to ductile transition temperature.
Bridging the Research to Application Divide: Recommendations for Community-Based Participatory Research in a Military Setting

ABSTRACTCurrently, in the United States, of 100 military service members needing behavioral health care it is estimated that around 50 would receive any care and only 30 to 50 would be provided “minimally adequate” care according to clinical, evidence-based standards. The current article discusses the existing gap between research and application and proposed reasons for this disparity. We briefly highlight existing research approaches developed by various disciplines (e.g., public health, psychology, social work) to address the research to application gap and provide example opportunities for the military's use of a community-based participatory approach. We also provide recommendations for a way forward to promote a research approach that utilizes both cutting-edge research methods and the richness of the applied expertise provided by military personnel. The recommended research approach aims to empower those individuals who provide or receive social, behavioral, or mental health services by creating an...
Exploring outcomes and evaluation in narrative pedagogy: An integrative review

Abstract Objectives To identify narrative pedagogy learning outcomes and evaluation methods used for pre-licensure nursing students. Recommend areas for expanding narrative pedagogy research. Design An integrative review using a modified version of Cooper's 1998 framework, as described by Whittemore and Knafl (2005). Data sources A computer-assisted search of the literature from 1995 to 2015 was performed using the search terms narrative pedagogy and nursing. Databases included the Cumulative Index to Nursing and Allied Health Literature, Academic Search Premier, Educational Resources Information Center, Educational Research Complete, Medline, PsychArticles, PsychINFO, and the Teacher Reference Center. Ancestry searches led to the inclusion of additional articles. Review methods Twenty-six texts met the criteria for full review and were evaluated for methodological rigor and relevance to the review aims. Nine articles achieved an acceptable quality score and were used for thematic analysis. Results Learning outcomes associated with narrative pedagogy were grouped into five themes: thinking, empowerment, interconnectedness, learning as a process of making meaning, and ethical/moral judgment. Multiple methods of evaluation are necessary to evaluate these learning outcomes. Conclusions Narrative pedagogy may be a beneficial philosophical approach to teaching. However, at this time, there is insufficient evidence to recommend its universal adoption. It is too broad in its approach to reliably measure its effectiveness. Future research should examine the effectiveness of specific teaching strategies to promote desired learning outcomes.
Gallery of double-contrast terminology

This article visually defines the descriptive terms commonly used in double-contrast gastrointestinal radiology. The terms are organized by whether they primarily refer to mucosal, wall, or extrinsic abnormalities.
Wirtschaftskunde des Kreditwesens

Das Wirtschaftsgeschehen wird durch zwei entgegengesetzte Kreislaufbewegungen bestimmt, durch den Guterkreislauf und den Geldkreislauf. Die Kreditinstitute als Unternehmungen, die gewerbsmasig das Kreditgeschaft betreiben und im Zahlungs- und Wertpapierverkehr tatig sind, stehen nur im Geldkreislauf, wo sie eine Vermittler-funktion ausuben.
New vision, new paradigm: health and wealth for all by 2100 - or for no one

Global environmental change is threatening the health and survival of humankind -are we doing enough to ensure the environmental and social bases for health?.
Microfiber Masses Recovered from Conventional Machine Washing of New or Aged Garments

Synthetic textiles can shed numerous microfibers during conventional washing, but evaluating environmental consequences as well as source-control strategies requires understanding mass releases. Polyester apparel accounts for a large proportion of the polyester market, and synthetic jackets represent the broadest range in apparel construction, allowing for potential changes in manufacturing as a mitigation measure to reduce microfiber release during laundering. Here, detergent-free washing experiments were conducted and replicated in both front- and top-load conventional home machines for five new and mechanically aged jackets or sweaters: four from one name-brand clothing manufacturer (three majority polyester fleece, and one nylon shell with nonwoven polyester insulation) and one off-brand (100% polyester fleece). Wash water was filtered to recover two size fractions (>333 μm and between 20 and 333 μm); filters were then imaged, and microfiber masses were calculated. Across all treatments, the recovered microfiber mass per garment ranged from approximately 0 to 2 g, or exceeding 0.3% of the unwashed garment mass. Microfiber masses from top-load machines were approximately 7 times those from front-load machines; garments mechanically aged via a 24 h continuous wash had increased mass release under the same wash protocol as new garments. When published wastewater treatment plant influent characterization and microfiber removal studies are considered, washing synthetic jackets or sweaters as per this study would account for most microfibers entering the environment.
Opportunities and Gaps in Primary Care Preventative Health Services for Transgender Patients: A Systemic Review.

Abstract Purpose: Transgender people face barriers to accessing healthcare, resulting in population-level disparities in health outcomes. Little research is available to better understand the receipt of primary healthcare among transgender patients or how the rate of receipt of preventive care may differ among transgender populations. Methods: The medical literature regarding U.S. adult transgender primary healthcare was reviewed using a keyword search strategy: transgender OR transsexual OR transvestite OR gender nonconforming for articles published between January 1, 2001 and June 15, 2015. Studies addressing the following topics as assessed by the Behavioral Risk Factor Surveillance System were extracted for qualitative review: colorectal cancer screenings, mammography or chest/breast tissue examinations, cholesterol and blood pressure screenings, tobacco use and smoking cessation, cervical cancer or human papillomavirus (HPV) screenings, human immunodeficiency virus (HIV), annual flu shot, and insuran...
Social media mining for identification and exploration of health-related information from pregnant women.

Widespread use of social media has led to the generation of substantial amounts of information about individuals, including health-related information. Social media provides the opportunity to study health-related information about selected population groups who may be of interest for a particular study. In this paper, we explore the possibility of utilizing social media to perform targeted data collection and analysis from a particular population group -- pregnant women. We hypothesize that we can use social media to identify cohorts of pregnant women and follow them over time to analyze crucial health-related information. To identify potentially pregnant women, we employ simple rule-based searches that attempt to detect pregnancy announcements with moderate precision. To further filter out false positives and noise, we employ a supervised classifier using a small number of hand-annotated data. We then collect their posts over time to create longitudinal health timelines and attempt to divide the timelines into different pregnancy trimesters. Finally, we assess the usefulness of the timelines by performing a preliminary analysis to estimate drug intake patterns of our cohort at different trimesters. Our rule-based cohort identification technique collected 53,820 users over thirty months from Twitter. Our pregnancy announcement classification technique achieved an F-measure of 0.81 for the pregnancy class, resulting in 34,895 user timelines. Analysis of the timelines revealed that pertinent health-related information, such as drug-intake and adverse reactions can be mined from the data. Our approach to using user timelines in this fashion has produced very encouraging results and can be employed for other important tasks where cohorts, for which health-related information may not be available from other sources, are required to be followed over time to derive population-based estimates.
Direct Observation of Adolescents with Serious Emotional Disturbance and Their Nonhandicapped Peers in Mainstream Vocational Education Classrooms

The purpose of the present study was to determine whether the behavior of students with serious emotional disturbance differs from that of their nonhandicapped peers in integrated vocational classrooms and to determine whether teachers instruct students with serious emotional disturbance differently than they do students with no handicaps. Eleven pairs of students and their teachers were observed in a variety of vocational settings. Overall, the behavior of the two student groups did not differ significantly, nor did the behavior of teachers differ towards the students. The results are discussed in terms of integrating students with serious emotional disturbance into mainstream vocational education classes.
A new gas–solid reaction model for voloxidation process with spallation

Abstract A new methodology, the crack–spallation model, has been developed to analyze gas–solid reactions dominated by crack growth inside of the solid reactant and spallation phenomena. The new model physically represents three processes of the reaction progress: (1) diffusion of gas reactant through pores; (2) growth of product particle in pores; and (3) crack and spallation of solid reactant. The validation of this method has been conducted by comparison of results obtained in an experiment for oxidation of UO2 and the shrinking core model. The reaction progress evaluated by the crack–spallation model shows better agreement with the experimental data than that evaluated by the shrinking core model. To understand the trigger point during the reaction progress, a detailed analysis has been conducted. A parametric study also has been performed to determine mass diffusivities of the gas reactant and volume increase constants of the product particles. This method can be appropriately applied to the gas–solid reaction based on the crack and spallation phenomena such as the voloxidation process.
Neer Award 2018: the effect of preoperative education on opioid consumption in patients undergoing arthroscopic rotator cuff repair: a prospective, randomized clinical trial.

Background Opioids are commonly administered for the treatment of acute and chronic pain symptoms. The current health care system is struggling to deal with increasing medication abuse and rising mortality rates from overdose. Preoperative patient-targeted education on opioid use is an avenue yet to be explored. The purpose of the study was to determine whether preoperative narcotics education reduces consumption after arthroscopic rotator cuff repair (ARCR). Methods Patients undergoing primary ARCR at our institution were randomized to receiving opioid-related preoperative education or not. Patients filled out preoperative questionnaires detailing complete medical history and visual analog scale (VAS) for pain. Patients completed questionnaires regarding their opioid consumption and pain at their 2-week, 6-week, and 3-month follow-up. Results The study enrolled 140 patients. Patients in the study group consumed significantly less narcotics than the control group at the 3-month follow-up. Patients in the education group were 2.2 times more likely to discontinue narcotic use by the end of follow-up (odds ratio, 2.19; P = .03). In addition, patients with a history of preoperative narcotic use that were in the education group were 6.8 times more likely to discontinue narcotics by the end of follow-up (odds ratio, 6.8; P = .008). Discussion/conclusions The findings of this study determined that preoperative education intervention significantly decreased the number of narcotic pills consumed at 3 months after ARCR. In addition, education resulted in earlier cessation of opioids; therefore, directed patient education can help alleviate the current opioid epidemic.
Performing China on the London Stage: Chinese Opera and Global Power, 1759–2008 by Ashley Thorpe (review)

Ashley Thorpe’s Performing China on the London Stage makes an important contribution to the scholarship on theatre history, Chinese opera, Sino-British contacts, orientalism, and intercultural perf...
Interventions in the Pathways Model

This chapter details multilevel intervention plans based on the principles and concepts underlying the Pathways Model. The main focus of the Level One interventions is to reestablish normal biological rhythms that have been disrupted by conditioning, stress, or trauma. Skill building is the main objective of the Level Two interventions, for example, developing relaxation skills to calm the body, exercising to improve physical condition, and redirecting the mind towards positive thoughts. The Level Three interventions consist of more sophisticated psychophysiological and medical interventions.
Perinatal depression—The fourth inflammatory morbidity of pregnancy?: Theory and literature review

Perinatal depression is one of the leading causes of maternal morbidity and mortality. The biological etiology of this disorder remains in question, despite considerable research into the contributions of hormonal imbalance, the role of monoamines, and dysregulation of the HPA axis. Because inflammation is known to be associated with major depression in men and non-perinatal women as well as with other important morbidities of pregnancy (such as preeclampsia, preterm birth, and gestational diabetes), and because these morbidities may correlate with perinatal depression, inflammation may be a common physiological pathway that can also help explain perinatal depression. In this paper, we review the theoretical background of inflammation in perinatal depression and then review the literature concerning immune and inflammatory factors in the etiology and course of perinatal depression. We close with recommendations for future studies in this still relatively unexplored area. Identification and understanding of a common pathophysiology between other pregnancy morbidities and perinatal depression would link physical and mental well-being, likely leading to better treatment and prevention.
Fifty Years of Progress in the Study of the Catalytic Synthesis of Ammonia

The catalytic synthesis of ammonia developed in Germany in the 1908 to 1913 period has probably been studied more extensively during the past 50 years than any other catalytic reaction. Research endeavors include the development of a method for measuring the surface area of the catalysts; a study of the adsorption of both hydrogen and nitrogen by the iron catalysts; a phase-rule study of the formation of nitrides of iron from ammonia-hydrogen mixtures; a study of the distribution of promoters on the catalyst surface; methods for estimating the fraction of adsorbed nitrogen present in the molecular form; and estimates from infrared spectroscopy, from LEED measurements, and from ion-emission spectroscopy as to the path followed during synthesis and the catalyst planes important in the synthesis. Recently, revolutionary nonferrous catalysts severalfold more active than standard iron catalysts have been prepared by Ozaki. These throw new light on the mechanism of the catalytic synthesis of ammonia.
Embodied Affect in Tutorial Dialogue: Student Gesture and Posture

Recent years have seen a growing recognition of the central role of affect and motivation in learning. In particular, nonverbal behaviors such as posture and gesture provide key channels signaling affective and motivational states. Developing a clear understanding of these mechanisms will inform the development of personalized learning environments that promote successful affective and motivational outcomes. This paper investigates posture and gesture in computer-mediated tutorial dialogue using automated techniques to track posture and hand-to-face gestures. Annotated dialogue transcripts were analyzed to identify the relationships between student posture, student gesture, and tutor and student dialogue. The results indicate that posture and hand-to-face gestures are significantly associated with particular tutorial dialogue moves. Additionally, two-hands-to-face gestures occurred significantly more frequently among students with low self-efficacy. The results shed light on the cognitive-affective mechanisms that underlie these nonverbal behaviors. Collectively, the findings provide insight into the interdependencies among tutorial dialogue, posture, and gesture, revealing a new avenue for automated tracking of embodied affect during learning.
Setting Specifications for Drug Substances

This article discusses the purpose of a drug substance specification and the variety of tests to be considered for inclusion. The relevance of these aspects to stability studies is examined and the differences between release testing and tests relevant to stability studies are explored. A scientific approach to setting drug substance specifications and to designing stability studies is encouraged and where necessary, the regulatory landscape is compared and contrasted to this approach.
Governmental Organization and Control Over Environmental Policies

Cuba has a vast number of agencies controlling its interior lands, coastal and maritime areas. This chapter describes the framework of these agencies, institutes and how their existence is linked to catalysts such as the Earth Summit in Rio de Janeiro in 1992. There are also two maps in this chapter that illustrate the year protected areas were established as well as what general entity is in charge of each protected area. The chapter concludes with the Ministry responsible for human health issues. The reason for its inclusion here is the direct link between a healthy environment and a healthy population.
Multifaceted Evaluation Criteria of Digital Libraries in Academic Settings: Similarities and Differences From Different Stakeholders

Abstract Digital library (DL) evaluation is essential to the success and enhancement of DLs. However, there is a lack of research on the assessment of comprehensive evaluation criteria across multiple dimensions of DLs. In particular, limited research is available on criteria prioritization to determine which criteria are perceived important by different stakeholders. This study was conducted to compare similarities and differences in perceptions of the importance of different DL evaluation criteria by heterogeneous stakeholders in academic settings. Ninety subjects were recruited with 30 from each of the group representing DL scholars, DL librarians, and DL users. Subjects were instructed to fill in an in-depth survey consisting of 10 evaluation dimensions with 94 criteria. ANOVA and t-test were applied to examine the similarities and differences among the three groups. This study reveals consensus and divergence in perceptions of criteria importance among the three groups, and indicates an inherent tension among the stakeholders. Moreover, the differences identify gaps not only between user expectations and the DL practice but also between what's desirable and what's possible in the academic environment. The findings provide a comprehensive list of criteria to guide practical evaluation of DLs, and contribute to the narrowing of the identified gaps.
Transformative power of city play: social media and place in a post-affordance world

ABSTRACTU.S. cities annually spend over $6 billion in building and maintaining public parks that afford places for social and physical activity. However, adolescent tendencies toward physical inact...
High-Pressure Vapor−Liquid Equilibria of 1-Alkyl-1-Methylpyrrolidinium Bis(trifluoromethylsulfonyl)imide Ionic Liquids and CO2

The high-pressure vapor–liquid equilibrium for the binary systems of carbon dioxide (CO2) and a series of 1-alkyl-1-methyl pyrrolidinium bis(trifluoromethylsulfonyl)imide ionic liquids ([CnC1pyr][N...
Seeing teacher-designer-curriculum research through an ergonomic lens: Commentary

Abstract In this commentary, we look across the articles in this volume to address the question – what does an ergonomic lens help us see that existing analytic lenses do not? Given that research using an ergonomic lens is relatively new and still emerging, we address this question from the perspectives of both what the current research, as represented in this volume, can help us see and understand, as well as what future research might consider and help us understand more deeply.
Specification Mining and Robust Design under Uncertainty: A Stochastic Temporal Logic Approach

In this paper, we propose Stochastic Temporal Logic (StTL) as a formalism for expressing probabilistic specifications on time-varying behaviors of controlled stochastic dynamical systems. To make StTL a more effective specification formalism, we introduce the quantitative semantics for StTL to reason about the robust satisfaction of an StTL specification by a given system. Additionally, we propose using the robustness value as the objective function to be maximized by a stochastic optimization algorithm for the purpose of controller design. Finally, we formulate an algorithm for parameter inference for Parameteric-StTL specifications, which allows specifications to be mined from output traces of the underlying system. We demonstrate and validate our framework on two case studies inspired by the automotive domain.
Multi-product pickup and delivery supply chain design with location-routing and direct shipment

Abstract This paper presents a decision making model that considers distribution centers locating, pickup and delivery vehicle routing, and direct shipment simultaneously. The goal is to optimize the distribution centers’ location, the delivery, pickup, and direct shipment routes so that the total costs are minimized. Two types of delivery modes are considered. In the first type, each vehicle loads the same type of products and in the second type, each vehicle is allowed to load multiple types of products. An integrated mixed integer linear programming model was formulated for each delivery type. Computational experiments were conducted to validate the models. Three solution methods: deterministic mode, opportunistic mode, and benders decomposition algorithm in CPLEX have been analyzed.
Partial Differential Equation Models

In this chapter we present a number of partial differential equation models for information diffusion in online social networks with friendship hops as distance metrics. First, we discuss embedding of graphs of online social networks into Euclidean spaces. We develop a conceptual framework that divides the information diffusion process over online social networks into two separate processes: external and internal influences. We establish a general framework for partial differential equation models and discuss three diffusive logistic models and then validate them with the Digg and Twitter datasets.
Adaptive additive classification-based loss for deep metric learning.

Recent works have shown that deep metric learning algorithms can benefit from weak supervision from another input modality. This additional modality can be incorporated directly into the popular triplet-based loss function as distances. Also recently, classification loss and proxy-based metric learning have been observed to lead to faster convergence as well as better retrieval results, all the while without requiring complex and costly sampling strategies. In this paper we propose an extension to the existing adaptive margin for classification-based deep metric learning. Our extension introduces a separate margin for each negative proxy per sample. These margins are computed during training from precomputed distances of the classes in the other modality. Our results set a new state-of-the-art on both on the Amazon fashion retrieval dataset as well as on the public DeepFashion dataset. This was observed with both fastText- and BERT-based embeddings for the additional textual modality. Our results were achieved with faster convergence and lower code complexity than the prior state-of-the-art.
Scattering of Short Radar Pulses from Multiple Wires and from a Chaff Cloud

We here present a calculation of the transient, short-pulse response of perfectly conducting wires, and its extension to chaff clouds consisting of multiple, randomly distributed and oriented wires (modeled by up to 12,000 wires of equal length). This calculation is based on the analytic wire cross section formulas of Einarsson1. These have been programed by us using computer-generated random-number sets of position and orientation parameters, in order to obtain responses characteristic for the size of the chaff cloud, and its wire distribution in location and orientation.
Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes

Several immunotherapies have demonstrated endogenous insulin preservation in recent-onset type 1 diabetes (T1D). We considered the primary results of rituximab, abatacept, teplizumab, alefacept, hi...
WE ARE HERE FOR YOU: INFERTILITY CLINIC WEBSITE COMMUNICATION DURING THE ESCALATING STAGES OF THE COVID-19 PANDEMIC

Objective: On March 17th, ASRM published guidance for REI clinics regarding infertility treatment during the COVID-19 pandemic The recommendations advised against initiation of new fertility treatment cycles outside of emergent fertility preservation Our objective was to evaluate what SART-member fertility clinics communicated to the public and their patients via clinic websites during this time period Design: Cross-sectional study Materials and Methods: Between 4/20/20 and 4/24/20, SART-member fertility clinic websites were reviewed for REI-specific COVID-19 messages (REI-CM) The REI-CM was evaluated for: type of treatment offered, and to whom;adherence to updated ASRM guidance;and citation of ASRM (or other) guidance Each website was evaluated by two reviewers and arbitrated by a third in the case of discrepancies Practice size, type, and location were abstracted from SART Clinics were classified by whether they were under a shelter in place (SIP) order and the duration of that order Chi squared analyses were performed to determine associations between clinic demographics and patterns in messaging Results: 381 SART-member clinics maintained active websites Of those, 249 (65 3%) had REI-CM The presence of REI-CM was more common in private than academic practices (73% vs 38%, p1000 cycles (p1000 cycles a year (18%, p=0 009), with a trend toward practices in the northeast (16%, p=0 113) and in states with SIP orders lasting <30 days (14%, p=0 09) Clinics treating all-comers were less likely to cite ASRM than other clinics (41% vs 62%, p=0 045) However, 75% (n=14) cited COVID-19 guidance from WHO, CDC and state and local governments Conclusions: While public messaging may not reflect the actual practices of a clinic, this study reveals heterogeneity in how clinics incorporated ASRM recommendations and responded to the early stages of the COVID-19 pandemic Academic practices were more likely to indicate their adherence to ASRM recommendations High volume groups were more likely to communicate with their patients about what treatments they offered and to treat patients outside ASRM guidance Lessons learned may inform optimal response in future waves of COVID-19 References: American Society for Reproductive Medicine Patient Management and Clinical Recommendations During The Coronavirus (COVID-19) Pandemic Available at Accessed on May 26, 2020
Why Ricardo’s Theory of Comparative Advantage Regarding Foreign Trade Doesn’t Work in Today’s Global Economy: Labor Arbitrage, Disloyal Capital, WTO Violations and National Security Implications

The theoretical basis for international trade is Ricardo’s theory of comparative advantage. Paul Samuelson, one of the leading lights in the economics profession in the 20th century, referred to it as one of the most beautiful ideas in economics. Yet, no one seems to have considered its validity in the context of the current global trade environment. What free-trade advocates have not done is to look at the bases underlying Ricardo’s theory, namely, that capital is loyal to the country of origin and that the value of currencies is responsive to imbalances in trade. This article demonstrates that capital is not loyal to the country of origin and that currencies do not move to smooth out imbalances in trade. This then forces us to look at the political, economic, and national security aspects of global trade, rather than just repeating the mantra that free trade benefits all. Clearly, there are winners and losers and, thus far, American workers have been the losers. The last election demonstrates that exporting jobs to countries such as China has domestic political consequences when people believe that the system is not working for them. The article then asserts we need an industrial policy for this country that seeks to benefit not just shareholders but also workers, and which recognizes the national security implications of global trade and the danger of supply chains that run through a potential adversary.
The Private Impact of Public Data: Landsat Satellite Maps Increased Gold Discoveries and Encouraged Entry

How does public data shape the relative performance of incumbents and entrants in the private sector? Using a simple theoretical framework, I argue that public data reduces investment uncertainty, ...
Thalamic state controls timing and synchronization of primary somatosensory cortical representations in the awake mouse

Summary The thalamus controls transmission of sensory signals from periphery to cortex, ultimately shaping perception. Despite this significant role, dynamic thalamic gating and the consequences for downstream cortical sensory representations have not been well studied in the awake brain. We optogenetically modulated the ventro-posterior medial thalamus in the vibrissa pathway of the awake mouse, and measured spiking activity in the thalamus, and at the level of primary somatosensory cortex (S1) using extracellular electrophysiology and genetically encoded voltage imaging. Thalamic hyperpolarization significantly amplified thalamic sensory-evoked spiking through enhanced bursting, yet surprisingly the S1 cortical response was not amplified, but instead timing precision was significantly increased, spatial activation more focused, and there was an increased synchronization of cortical inhibitory neurons. A thalamocortical network model implicates the precise timing of feedforward thalamic spiking, and timing-sensitive engagement of synaptic depression, presenting a highly sensitive, state-dependent timing-based gating of sensory signaling to cortex.
Eliciting a Mode of Transportation to Improve Product Life Cycle Performance

The purpose of this paper is to describe how to implement the utility theory to a supply chain problem. In this problem, two different modes of freight transportation are compared to improve life cycle performance of a mass product: trucks and trains. First, the problem is described, the criteria and attributes are introduced and the dataset for this problem is defined. Then, a description of the utility theory model is conducted, explaining the choice of the multiplicative model instead of the additive one. After that, the utility functions for each attribute are elicited, and a trade-off analysis is conducted in order to define indifference points and to calculate the scaling factors. Then, the aggregation function is formulated for this problem, the alternatives ranked, and the best mode of transportation elicited.
Silicates in Carbonate Speleothems, Guadalupe Mountains, New Mexico, U.S.A.

Silicates such as amorphous silica, quartz, trioctahedral smectite (stevensite), and possibly kerolite have formed with carbonate minerals in carbonate speleothems from caves of the Guadalupe Mountains, New Mexico, U.S.A. The likely sources of Si were the disseminated silicate minerals in situ in the Permian dolostone units in which the caves have developed. Ca- and Mg-carbonate mineral precipitation from thin water-films on speleothems due to evaporation and CO2 loss progressively increased the Si/(Ca+Mg) ratio, and concentrated the initially low percent of aqueous silica seeping into these caves. Amorphous silica precipitated with calcite and aragonite in stalagmites because the formation of these materials was rapid and the stalagmites are too young for the crystallization of quartz. The presence of organic material in the stalagmites hints that the amorphous silica may have an organic-related origin. Quartz and trioctahedral smectite formed with the Mg-carbonate minerals such as dolomite, huntite, and hydromagnesite. The authigenesis of quartz at the low temperature (15-25°C) of these caves, like that of well-ordered dolomite, required extensive periods of time (i.e., ≫1 ka) in a stable environment conducive for silicate precipitation. Kerolite-like silicates, in aragonite crusts, seemed to be intermediate precipitates between amorphous silicates and trioctahedral smectite.
Immunization of HLA-A2+ Melanoma Patients with MAGE-3 or MelanA Peptide-pulsed Autologous Peripheral Blood Mononuclear Cells Plus Recombinant Human Interleukin 12

Vaccination with dendritic cells (DCs) pulsed with tumor antigen peptides has shown promise in the treatment of melanoma. Interleukin (IL)-12 production by DCs is a key component for their efficacy. Murine studies have shown that IL-12 promotes potent antitumor immunization when coadministered with peptides loaded onto other class I MHC+ cells, thus bypassing the need to use DCs. The easiest cell source to obtain in large quantity from human patients is peripheral blood mononuclear cells (PBMCs). A Phase I clinical trial was thus performed in patients with metastatic melanoma using immunization with autologous PBMCs pulsed with a MAGE-3 or a MelanA peptide, coadministered with various doses of recombinant human (rh)IL-12. Patients receiving low-to-moderate doses of rhIL-12 developed increased specific CD8+ T-cell responses. Of the eight patients showing increased immunity, six had evidence of clinical activity, with one complete, one partial, one minor, and three mixed responses observed. In two patients with mixed responses, growing tumors were found to lack expression of the antigen used to immunize. Thus, vaccination with peptide-pulsed PBMCs plus rhIL-12 induces specific immunity and has clinical activity, without the need to generate DCs. Outgrowth of antigen-negative tumors argues for the future development of polyepitope vaccines.
BiCMOS current source reference network for ULSI BiCMOS with ECL circuitry

A BiCMOS current source reference network which eliminates the impact of DC power supply voltage drops on the operation of ECL (emitter coupled logic) circuits is described. This is essential for implementing ECL design techniques in ULSI BiCMOS circuits. Using the current source network, reference voltages are generated locally, so that the ECL voltage references are correctly referenced to the local power supply potentials. A power-supply-insensitive bandgap reference generator is used to generate precision on-chip voltage references and current sources. The bandgap reference circuit uses both MOS and bipolar transistors and is much simpler than a similar design using bipolar-only circuitry. The micrograph of the test chip containing the bandgap circuit nd BiCMOS op amp analog drivers is shown. The drivers are designed for multiple-reference-level regeneration. The test chip has been fabricated using a 0.8- mu m BiCMOS process. The typical characteristics of the bandgap circuit and the analog driver are shown. >
THE POTENTIAL OF COGNITIVE NEUROSCIENCE FOR INFORMATION SYSTEMS RESEARCH

This paper proposes the idea of applying cognitive neuroscience theories, methods, and tools in Information Systems (IS) research (termed “Neuro-IS”), and introduces a research agenda for exploring the potential of cognitive neuroscience for IS research. Recent cognitive neuroscience discoveries have clarified the neural bases of human psychological processes and behavior and provided insights that may advance progress on core IS research questions on designing and deploying IT tools, technology adoption and use, e-commerce, virtual teams, human-computer interaction, decision making, and information sharing in organizational and market environments, among others. Functional neuroimaging techniques (fMRI, PET, EEG, MEG) have led to a better understanding of the brain areas and structures involved when people make decisions, deal with risk, uncertainty, and ambiguity, respond to rewards and social influences, trust and distrust, cooperate and compete, and acquire and process information. Similar to economics, marketing, and psychology, IS research may also benefit from integrating some of these new discoveries in cognitive neuroscience into IS theories about how IT supports human processes. Moreover, the use of neuroimaging techniques in IS research could complement traditional methods and data, such as self-report surveys, interviews, lab and field experiments, and archival data to integrate new objective sources of brain data for IS theory development and testing. This paper provides several examples of potentially fertile intersections of cognitive neuroscience and IS research on such areas as technology adoption and use, e-commerce, and group support systems. The paper also overviews today’s functional neuroimaging tools and gives guidelines on how IS researchers can utilize these tools to obtain additional new insights into IS phenomena. Finally, it discusses the implications of incorporating cognitive neuroscience theories and functional neuroimaging tools in neuro-IS research, aiming to enhance the diversity of theories, methods, tools, and data in the portfolio of IS researchers.
Complex rotations in atomic scattering theory

There has recently been interest shown in the possibility of using the theory of analytic functions of a complex variable to overcome some of the difficulties encountered in calculating atomic scattering amplitudes. In this paper we discuss the complex rotation method, in which all coordinates are transformed by rj → rj eiα. Previous authors 1 have pointed out that this transformation makes it possible to describe the (complex) energy of a resonance as a discrete eigenvalue of the rotated Hamiltonian Hα which has the form $${H_\alpha } = {e^{ - 2i\alpha }}T + {e^{ - i\alpha }}V$$ (1) for purely Coulomb potentials.
Role of organic fertilizers in walleye (Sander vitreus) production in plastic-lined culture ponds

This study used six 0.04 ha plastic-lined ponds to compare the effects of a fertilization regime using a one-time initial application of an organic fertilizer (alfalfa pellets) with the current regime of weekly applications of organic fertilizers on the abundance and distribution of aquatic invertebrates and walleye, Sander vitreus, fingerling production. Walleye, 3–4 days post hatch, were stocked on 1 May 2002 and harvested on 6–7 June 2002. Throughout the growing season, a ratio of 7:1 total nitrate-nitrogen to total phosphorus was maintained in all ponds regardless of the treatment. Once fry were stocked, ponds in Treatment #1 were fertilized weekly with organic fertilizer (alfalfa pellets; 112 kg ha−1 week−1) for a total of 795 kg ha−1 pond−1. Ponds in Treatment #2 only received an initial application of alfalfa pellets (112 kg ha−1). Ponds in Treatment #1 had significantly higher ammonia and nitrate levels as well as higher chironomid larvae but not zooplankton compared with the other treatment. At harvest, walleye in the Treatment #1 ponds were significantly longer and heavier; however, the survival and relative weight were not significantly different. These results suggest that weekly applications of organics are important for the benthic food base and growth of fingerling walleye reared in plastic-lined ponds.