cssi/SciSciGPT-SciSciNet huggingface dataset:
Cell Proliferation Kinetics of the Internal Enamel Epithelium of Mouse Incisors

SYNOPSIS IN INTERLINGUACINETICA DEL PROLIFERATION CELLULAR IN LE EPITHELIO INTERO-ADAMANTIN DEL INCISORES DE MUSES.-Un analyse cinetic del proliferation de preameloblastos in le incisores de muses esseva effectuate a base de autoradiographias post le administration a thymidina a tritium. Le minime tempore generatori estimate a base del curva de mitosis esseva 14,2 horas. Le minime tempore del synthese de acido deoxyribonucleic, le minime tempore postsynthetic, le minime tempore mitotic e le minime tempore presynthetic esseva 5,5, 0,82, 0,5, e 7,4 horas, respectivemente. Le total tempore generatori medie de 24,0 horas esseva calculate a base del proportion de tempore medie del synthese de acido deoxyrobonucleic (7,2 horas) al indice de marcage (0,30). Esseva trovate que durante le processo de maturation preameloblastic quatro successive divisiones cellular occurre ante que le cellulas deveni ameloblastos functional. Le minime tempore de transito del preameloblastos es approximativemente 56,8 horas.
“Yes And”: The Uses of Improvisation for Early Childhood Professional Development

In their teacher preparation and professional development training, early childhood teachers learn about the importance of play for children’s development; yet they are rarely taught how to play with children. Once in the classroom, many teachers do not interact responsively to children’s play; instead they ignore, interpret, or dominate the activity. Building on the theory that play is a collective activity similar in form to improvised performances, and that teachers can develop their ability to play collectively, this article presents findings from a pilot project that explored the use of improvisational (“improv”) theatre workshops as a professional development tool for preparing teachers to be better players. The analysis of the data suggests that the skills associated with responsive teaching can be taught through participation in improv workshops and that learning to improvise can give teachers new ways to understand their role in the classroom.
Certain Implications for High-Energy Total Cross Sections from the Multiperipheral Model

The multiperipheral model is used to relate the experimental fact, ${{\ensuremath{\sigma}}_{N\overline{N}}}^{\mathrm{tot}}g{{\ensuremath{\sigma}}_{\mathrm{NN}}}^{\mathrm{tot}}$, to the possibility that the $N\overline{N}$ channel can annihilate into purely meson final states by exchange of $N$ or $\overline{N}$ trajectories, whereas the $\mathrm{NN}$ channel cannot do so. Our argument shows that from the multi-Regge bootstrap point of view, the combination of baryon and antibaryon trajectories will generate a pair of exchange-degenerate trajectories ${P}^{\ensuremath{'}}$ and $\ensuremath{\omega}$. The same line of reasoning can easily be generalized to include strange particles, as well as the (${K}^{\ensuremath{-}}N, {K}^{+}N$) and (${\ensuremath{\pi}}^{\ensuremath{-}}p, {\ensuremath{\pi}}^{+}p$) systems.
Preparation of curium oxysulfate and curium oxide by resin calcination

Abstract Calcination of Cm 3+ -form Dowex 50W-X8 resin in air or oxygen yields Cm 2 O 2 SO 4 at 900°C and Cm 2 O 3 at 1175°C. A stable compound, probably Cm 2 (SO 4 ) 3 , exists at 760°–870°C. The ionic radius of Cm 3+ in Cm 2 O 2 SO 4 is 0·980 A. Alpha radiation damage in 244 Cm 2 O 2 SO 4 causes loss of structure in ∼3 days and partial degradation to CmO 2 in ∼8 days.
Intraoperative assessment of mitral valve area after mitral valve repair for regurgitant valves.

A 37-year-old woman (body surface area 1.75 m2) was monitored using standard American Society of Anesthesiologists noninvasive monitors, intra-arterial and pulmonary artery catheters, and transesoph- ageal echocardiography (TEE). Baseline hemodynamic data are shown in Table 1. At the time of surgery, she was in a normal sinus rhythm. Before CPB, the examination showed diffuse bileaflet myxomatous dis- ease including prolapse of all scallops. There was severe mitral regur- gitation. The left ventricular ejection fraction was estimated to be 55%. Right ventricular function also was reduced. The remainder of the examination was not remarkable. The surgical procedure consisted of plication of P1 and P3, resection of P2, and placement of commissural sutures between A1 and P1 and between A3 and P3. Neochordae were placed to reduce the prolapsing middle anterior leaflet scallop. A 28-mm flexible Carpentier-Edwards (Irvine, CA) annuloplasty ring was placed. To facilitate separation from CPB, an epinephrine infusion was begun. Echocardiographic measurements and calculations of mitral valve
Spontaneous symmetry breaking derived from a stochastic interpretation of quantum mechanics

If the Heisenberg picture correlation functions of a quantum system coincide with the correlation functions of a classical stochastic process, the interpretation is viable that in each individual experiment the quantum system plays out one realization of the classical stochastic process. Such a hypothesis leads to predictions conventionally ascribed to spontaneous symmetry breaking.
Diffusion of sulfur in gallium phosphide and gallium arsenide

Abstract A radiotracer technique was used to study the diffusion of sulfur in GaP and GaAs as a function of temperature, sulfur pressure, and component pressure. The results reported here indicate that the variation of diffusion coefficient with component pressure for sulfur in both GaP and GaAs is not in agreement with a model of vacancy diffusion within a single sublattice. The diffusion coefficient of sulfur in GaP was found to be independent of phosphorus pressure, whereas the diffusion coefficient of sulfur in GaAs varied as ( P As 4 ) 1 2 at low arsenic pressures, and appeared to saturate at arsenic pressures greater than 0.5–1 atm. The results for sulfur in GaP are consistent with diffusion via the divacancy (V Ga V P ) while the diffusion of sulfur in GaAs can be explained by movement via the gallium divacancy (V Ga V Ga ). The apparent decrease in the diffusion coefficient at high sulfur concentrations can be qualitatively explained by the formation of the complex (V Ga S 3 ). A plasma reflection technique was used to study the electrically active part of the sulfur-diffused layers in GaAs. At high sulfur concentrations a large percentage of the sulfur in the diffused layer was found to be electrically inactive. This phenomenon is suggested as a possible explanation for the large discrepancy among previously reported values of the diffusion coefficient of sulfur in GaAs.
Analysis and control of transient torque response in engines with internal exhaust gas recirculation

We analyze the nonlinear dynamic behavior of an internal exhaust gas recirculation system based on a mean-value model of an experimental automotive engine equipped with a camshaft phaser. We develop a control scheme that adjusts camshaft timing to reduce feed-gas emissions while maintaining transient engine torque response similar to that of a conventional engine with zero exhaust gas recirculation. The control scheme consists of a feedforward map that specifies desired camshaft timing as a function of throttle position and engine speed in steady state, and a first-order lag that governs the transition of the camshaft timing to the desired value. The time constant of the first-order lag is adjusted based on engine speed and throttle position.
THE EFFECT OF ACONITINE ON THE GIANT AXON OF THE SQUID.

In the giant axon of Loligo pealii, "aconitine potent" Merck added to the bath (10-7 to 1.25 x 10-6 gm/ml) (a) had no effect on resting membrane potential, membrane resistance and rectification, membrane response to subthreshold currents, critical depolarization, or action potential, but (b) on repetitive stimulation produced oscillations of membrane potential after the spike, depolarization, and decrease of membrane resistance. The effect sums with successive action potentials; it increases with concentration of aconitine, time of exposure, and frequency of stimulation. When the oscillations are large enough and the membrane potential is 51.6 ± SD 1.5 mv a burst of self-sustained activity begins; it usually lasts 20 to 70 sec. and at its end the membrane potential is 41.5 ± SD 1.9 mv. Repolarization occurs with a time constant of 2.5 to 11.1 min. Substitution of choline for external sodium after a burst hyperpolarizes the membrane to -70 mv, and return to normal external sodium depolarizes again beyond the resting membrane potential. The effect of aconitine on the membrane is attributed to an increase of sodium and potassium or chloride conductances following the action potential.
Resistance against Reverse Transcriptase Inhibitors

The response to antiretroviral therapy in human immunodeficiency virus (HIV)-infected patients is limited by the emergence of drug resistance. This resistance is a consequence of the high rate of HIV mutation, the high rate of viral replication (especially when potent multidrug therapies are not used or taken reliably), and the selective effect of these drugs, which favors emergence of mutations that can establish clinical drug resistance. The introduction of highly active antiretroviral therapy (HAART), which typically includes at least 2 nucleoside reverse transcriptase inhibitors (RTIs) and a protease inhibitor or a nonnucleoside RTI, for most treatment-naive patients results in a reduction of viral load below the limit of detection determined by currently available HIV RNA assays. It is this marked reduction that results in durable viral suppression, usually only possible by the simultaneous use of 3 or 4 drugs. The RTI components of HAART are crucial for these benefits of combination therapy. Specific amino acid changes are associated with resistance to several RTIs, but new mutation complexes have been observed that can confer broad cross-resistance within this class. Genotypic and phenotypic resistance assays to measure drug resistance are being developed, but refinements in both methodology and our ability to interpret results of these assays are necessary before they are introduced into widespread clinical use.
Improved Cardiomyocyte Functions of Carbon Nanofiber Cardiac Patches

The objective of the present in vitro research was to determine cardiomyocyte functions on poly-lactic-co-glycolic acid (50:50 (PLA:PGA); PLGA) with greater amounts of carbon nanofibers (CNFs) using an in vitro electrical stimulation system for myocardial tissue engineering applications. The addition of CNFs can increase the conductivity and strength of pure PLGA. For this reason, different PLGA: CNF ratios (100:0, 75:25, 50:50, 25:75, 0:100 wt%) were created where conductivity and cytocompatibility properties under electrical stimulation with human cardiomyocytes were determined. Results showed that PLGA:CNF materials were conductive and that conductivity increased with greater amounts of PLGA added, from 0 S.m -1 for 100:0 wt% (pure PLGA) to 6.5x10 -3 S.m -1 for 0:100 wt% (pure CNFs) materials. Furthermore, results indicated that cardiomyocyte cell density increased with continuous electrical stimulation (rectangular, 2 nm, 5 V/cm, 1 Hz) after 1, 3, and 5 days as well as a slight increase in Troponin I excretion compared to non-electrically stimulated normal cardiomyocyte cell functions. This study, thus, provides an alternative conductive scaffold using nanotechnology which should be further explored for numerous cardiovascular applications.
Detection and classification of signals in impulsive noise modeled as an alpha-stable process

Studies the structure of the probability density function of random variables which are formed as the sum of two or more independent, symmetric stable random variables of different characteristic exponents. The authors present an asymptotic series expansion valid for large argument. Possible applications of the theory can be found in the problem of detection of impulsive stochastic transients superimposed over a background of Gaussian noise. >
Management of HIV infection in treatment-naive patients: a review of the most current recommendations.

Purpose The most current guidelines issued by the Department of Health and Human Services (DHHS) on the management of human immunodeficiency virus (HIV) infection in treatment-naive patients are reviewed. Summary Treatment guidelines are updated frequently because of the emergence of data demonstrating the risks and benefits of antiretroviral therapy. The DHHS guidelines strongly recommend initiating therapy in patients with certain conditions regardless of CD4 cell count and in patients with CD4 cell counts of 500 cells/mm3 is controversial. Although cumulative observational data and biological evidence support treatment at higher CD4 cell counts, randomized controlled trial data to support this are not available, and the risk of antiretroviral toxicities, resistance, non-adherence, and cost should be considered in individual patients. The preferred regimens have been consolidated to four options, including a dual-nucleoside reverse transcriptase inhibitor backbone (tenofovir plus emtricitabine) with a nonnucleoside reverse transcriptase inhibitor (efavirenz), a ritonavir-boosted protease inhibitor (atazanavir plus ritonavir or darunavir plus ritonavir), or an integrase strand-transfer inhibitor (raltegravir). Regimens are classified as alternative or acceptable when they have potential safety or efficacy concerns, have higher pill burdens, or require more-frequent administration compared with preferred regimens. Conclusion The DHHS 2011 guidelines advocate earlier antiretroviral therapy initiation than recommended in recent years, and preferred regimens have been refined to maximize efficacy, safety, and quality of life for treatment-naive HIV-infected patients.
Studies of frequency dependent C-V characteristics of neutron irradiated p/sup +/-n silicon detectors

Frequency-dependent capacitance-voltage (C-V) characteristics of neutron-irradiated high-resistivity silicon P/sup +/-n detectors have been observed up to a fluence of 8.0*10/sup 12/ n/cm/sup 2/. It has been found that the frequency dependence of the deviation of the C-V characteristic (from its normal V/sup -1/2/ dependence) is strongly dependent on the ratio of the defect density to the effective doping density N/sub t//N'/sub d/. As the defect density approaches the effective dopant density, or N/sub t//N'/sub d/ to 1, the junction capacitance eventually assumes the value of the detector geometry capacitance at high frequencies (f>or=10/sup 5/ Hz), independent of voltage. A two-trap-level model that uses the concept of quasi-Fermi levels and predicts the effects of C-V frequency dependence and dopant compensation observed has been developed. >
Study on grouping technology of Redox Flow Battery

The group technology, which leads battery cell combined in series-parallel ways scientifically, is the basis of large scale application of Battery Energy Storage System (BESS). Especially for VRB, as it holds a unique structure of hydraulic interconnection pipe system, the combination of electrical connection and hydraulic connection should be more challenging to the group technology. On the basis of experimental study of Vanadium Redox Flow Battery (VRB), the reliability, efficiency and economic analysis of battery group technology are discussed from the viewpoint of engineering application in this paper.
Assessing behavior and social competence of severely emotionally disturbed youth admitted to psychiatric residential treatment.

PROBLEM: Youth admitted to psychiatric residential treatment centers demonstrate behavioral problems and social competence deficits. Little systematic inquiry has quantified these issues or their impact on therapeutic care. METHOD: Secondary data from Child Behavioral Checklists and Relationship Questionnaires were collected through retrospective chart reviews and were statistically analyzed. FINDINGS: Seventy-one percent of the 113 subjects met clinical behavioral problem levels. Youth who were older than 15 years at admission lagged significantly behind 12th-grade norms in social competence, having scores congruent with 8th-grade students. CONCLUSION: Youth in this study had significant behavioral problems, and deficits in social competence were identified among older youth.
Familiality estimates from restricted samples

Abstract In a recent paper here, Benbow, Zonderman, and Stanley (1983) report that the coefficient of regression of offspring IQ on parental IQ is much lower among the gifted than in the population at large. Thus, Benbow, Stanley, Kirk, and Zonderman conclude in a second paper, the gifted resemble their parents less than do people in general. In this paper, I show that this result is an artifact of the particular estimator of the regression coefficient employed by Bendoq, Zonderman, and Stanley. The leastsquares estimator, which they employ, is severely biased downward, if the sample on the dependent variable is restricted to the upper tail of the distribution, and this is precisely the nature of Benbow et al.'s sample. That is to say, in a bivariate normal distribution with constant regression coefficient, samples restricted to values of the dependent variable (here, child's IQ) above a certain value will always produce a lower regression coefficient than unrestricted samples drawn from the entire but same distribution. I introduce an unbiased estimator that can be calculated from the sample statistics reported in the Benbow, Zonderman, and Stanley article and find that the coefficient of regression of gifted child's IQ on parental IQ is, in fact, higher than the regression coefficients reported in the literature for unrestricted samples. That is, Benbow et al.'s data suggest that the gifted in fact resemble their parents more than do persons in general.
Green tea catechins are potent sensitizers of ryanodine receptor type 1 (RyR1).

Abstract Catechins, polyphenols extracted from green tea leaves, have a broad range of biological activities although the specific molecular mechanisms responsible are not known. At the high experimental concentrations typically used polyphenols bind to membrane phospholipid and also are easily auto-oxidized to generate superoxide anion and semiquinones, and can adduct to protein thiols. We report that the type 1 ryanodine receptor (RyR1) is a molecular target that responds to nanomolar (−)-epigallocatechin-3-gallate (EGCG) and (−)-epicatechin-3-gallate (ECG). Single channel analyses demonstrate EGCG (5–10 nM) increases channel open probability (Po) twofold, by lengthening open dwell time. The degree of channel activation is concentration-dependent and is rapidly and fully reversible. Four related catechins, EGCG, ECG, EGC ((−)-epigallocatechin) and EC ((−)-epicatechin) showed a rank order of activity toward RyR1 (EGCG > ECG ≫ EGC >>> EC). EGCG and ECG enhance the sensitivity of RyR1 to activation by ≤100 μM cytoplasmic Ca2+ without altering inhibitory potency by >100 μM Ca2+. EGCG as high as 10 μM in the extracellular medium potentiated Ca2+ transient amplitudes evoked by electrical stimuli applied to intact myotubes and adult FDB fibers, without eliciting spontaneous Ca2+ release or slowing Ca2+ transient recovery. The results identify RyR1 as a sensitive target for the major tea catechins EGCG and ECG, and this interaction is likely to contribute to their observed biological activities.
A Septin from the Filamentous Fungus A. nidulans Induces Atypical Pseudohyphae in the Budding Yeast S. cerevisiae

Background Septins, novel cytoskeletal proteins, form rings at the bases of emerging round buds in yeasts and at the bases of emerging elongated hyphal initials in filamentous fungi. Methodology/Principal Findings When introduced into the yeast Saccharomyces cerevisiae, the septin AspC from the filamentous fungus Aspergillus nidulans induced highly elongated atypical pseudohyphae and spore-producing structures similar to those of hyphal fungi. AspC induced atypical pseudohyphae when S. cerevisiae pseudohyphal or haploid invasive genes were deleted, but not when the CDC10 septin gene was deleted. AspC also induced atypical pseudohyphae when S. cerevisiae genes encoding Cdc12-interacting proteins Bem4, Cla4, Gic1 and Gic2 were deleted, but not when BNI1, a Cdc12-interacting formin gene, was deleted. AspC localized to bud and pseudohypha necks, while its S. cerevisiae ortholog, Cdc12, localized only to bud necks. Conclusions/Significance Our results suggest that AspC competes with Cdc12 for incorporation into the yeast septin scaffold and once there alters cell shape by altering interactions with the formin Bni1. That introduction of the A. nidulans septin AspC into S. cerevisiae induces a shift from formation of buds to formation of atypical pseudohyphae suggests that septins play an important role in the morphological plasticity of fungi.
Disability and Feminism

Abstract The author concludes that Goffman's description of the difficulties involved in identity management for persons with disabilities are as true now as when Stigma was first written. However, Goffman was unaware of the interaction between disability and feminism when he wrote Stigma in 1963. Women with disabilities are subject to additional disadvantages in ways that many professionals may not recognize. Suggestions are offered for human services professionals when working with women who have disabilities.
A security framework for protecting traffic between collaborative domains

In this paper, we propose a novel Secure Name Service (SNS) framework for enhancing the service availability between collaborative domains (e.g., extranets). The key idea is to enforce packet authentication through resource virtualization and utilize dynamic name binding to protect servers from unauthorized accesses, denial of service (DOS) and other attacks. Dieren t from traditional static network security schemes such as VPN, the dynamic name binding of SNS allows us to actively protect critical resources through distributed ltering mechanisms built in collaborative domains. In this paper, we present the architecture of the SNS framework, the design of SNS naming scheme, and the design of authenticated packet forwarding. We have implemented the prototype of authenticated packet forwarding mechanism on Linux platforms. Our experimental results demonstrate that regular Linux platforms are sucien t to support the SNS authenticated packet forwarding for 100Mbps and 1Gbps Ethernet LANs. To further improve the performance and scalability, we have also designed and implemented unique two-layer fast name lookup schemes.
A microfluidically switched feed network for beam-scanning focal plane arrays

A microfluidically switched feed network is designed for beam-scanning focal plane arrays by utilizing a selectively metallized plate within the microfluidic channel. As compared to the prior work that microfluidically repositioned a patch antenna element behind the lens for beam-scanning, the presented feed network approach is shown to provide higher efficiency and bandwidth performance. The design is carried out at Ka-Band (30 GHz) for an aperture coupled patch antenna array located at the focal plane of an extended hemispherical dielectric lens.
Effects of Actual and Simulated Seedcorn Maggot (Diptera: Anthomyiidae) Damage on Soybean Growth and Yield

Interactive damage effects of stand loss and plumule abscision from seedcorn maggot, Hylemya platura (Meigen), on ‘Amsoy 71’ soybean growth and yield were investigated by using actualand simulated-damage methods. Stand reduction affected seed yield more than the presence of surviving seedlings wihtout plumules. Over all years, seed yields were greatest at 29.7 plants per 1-m row. At all plant stands, the seedlings without plumules were shorter and produced less leaf area, fewer flowers, and fewer pods than did normal plants. This retarded growth reduced leaf area index, flowers per unit area, and pods per unit area. The decrease in pods per unit area was accompanied by an increase in beans per pod. When some of the surviving seedlings lacked plumules, seed yields were reduced at poor plant stands in some years. Plant-growth characteristics were very similar for actual and simulated damage. Seed yield comparisons between actual and simulated damage suggested that seedcorn maggot injury to cotyledons had a small, negative effect on seed yield
Radioimmunoassay Quality Control and Troubleshooting

This is the third continuing education article in a four-part series on radioimmunoassay. After reading and studying this article, the reader should be able to: 1) describe the procedures used for immunoassay quality control; 2) state acceptable limits of results; and 3) discuss troubleshooting approaches.
A Quantitative Study of Cavity Evolution in An Al-Cu-Zr Alloy

Experiments were conducted on a superplastic aluminum-based alloy containing 6% Cu and 0.5% Zr. Specimens were pulled in tension under selected experimental conditions and then polished and examined with an optical microscope connected through a video camera to an image monitor and a personal computer. A software package was used to provide quantitative information on the cavity morphologies including the number of cavities in a selected area, their size, their deviation from a circle, and the orientation of their longest length with respect to the tensile axis. Results are presented showing the change in cavity morphology with elongation and the effect of testing at different strain rates.
SMARTCheck Solution for Limited Resources

ABSTRACTPersistent access to library spaces and collections with limited staffing due to budget constraints can easily transition into a circulation nightmare. A lack of information control can result in materials being removed with no record of current location or usage data. A dedicated focus on student integrity combined with the leveraging of new but familiar technologies allowed the Medical Sciences Library of Texas A&M University to overcome both physical and fiscal barriers. In addition, the novel method of capturing circulation usage allowed for expanded services and opportunities for additional interactions with library users.
SURVEY ON PRESENT STATUS OF DISINFECTION AND ISOLATION IN COMMUNITY HEALTH SERVICE INSTITUTIONS OF FANGSHAN DISTRICT

Objective To know the situation of disinfection and isolation in community health service centers(stations) in Fangshan District,to provide the reference for standard management.Method On-the-spot investigation and sampling monitor were used to investigate the status of disinfection and isolation of 195 community health service centers(stations) in Fangshan District.Results In this investigation of the 195 home CHS institutions,82% of the community health service centers equipped with mobile hand-washing facilities,only 43% of them equipped with qualified dry hand disinfectant.The qualified rate of ultraviolet lamp radiation intensity was 85.1% in community health service agencies,the records of ultraviolet light was 70% in them.The qualified rate of medical staff hand hygiene was 90.7% in community health station.Conclusion The status of disinfection and isolation was not optimistic in community health service agencies.The quality qualified rate of hand hygiene of medical personnel was low,the same as the equipment rate of hand quickly disinfectant.We should strengthen management,improve the strength of supervision and monitoring.
SU-F-T-23: Correspondence Factor Correction Coefficient for Commissioning of Leipzig and Valencia Applicators with the Standard Imaging IVB 1000

Purpose: To determine the correction factor of the correspondence factor for the Standard Imaging IVB 1000 well chamber for commissioning of Elekta’s Leipzig and Valencia skin applicators. Methods: The Leipzig and Valencia applicators are designed to treat small skin lesions by collimating irradiation to the treatment area. Published output factors are used to calculate dose rates for clinical treatments. To validate onsite applicators, a correspondence factor (CFrev) is measured and compared to published values. The published CFrev is based on well chamber model SI HDR 1000 Plus. The CFrev is determined by correlating raw values of the source calibration setup (Rcal,raw) and values taken when each applicator is mounted on the same well chamber with an adapter (Rapp,raw). The CFrev is calculated by using the equation CFrev =Rapp,raw/Rcal,raw. The CFrev was measured for each applicator in both the SI HDR 1000 Plus and the SI IVB 1000. A correction factor, CFIVB for the SI IVB 1000 was determined by finding the ratio of CFrev (SI IVB 1000) and CFrev (SI HDR 1000 Plus). Results: The average correction factors at dwell position 1121 were found to be 1.073, 1.039, 1.209, 1.091, and 1.058 for the Valencia V2, Valencia V3, Leipzig H1, Leipzig H2, and Leipzig H3 respectively. There were no significant variations in the correction factor for dwell positions 1119 through 1121. Conclusion: By using the appropriate correction factor, the correspondence factors for the Leipzig and Valencia surface applicators can be validated with the Standard Imaging IVB 1000. This allows users to correlate their measurements with the Standard Imaging IVB 1000 to the published data. The correction factor is included in the equation for the CFrev as follows: CFrev= Rapp,raw/(CFIVB*Rcal,raw). Each individual applicator has its own correction factor, so care must be taken that the appropriate factor is used.
Hewlett-Packard's WEEE management strategy

Abstract: This chapter describes Hewlett-Packard’s approach to environmental business management and electronic waste (e-waste) in particular. Section 27.1 describes environmental business management at HP, including a description of its strategy and approach, and the business benefits and challenges that have resulted. Section 27.2 provides a case study of HP’s e-waste management system. it focuses on HP’s end-of-life product return and recycling, and includes insights from an industry perspective. Section 27.3 discusses trends that HP expects to have an impact on WEEE and WEEE management in the future.
Developing Shariah - Compliant Financial Services for the Muslim Customers in India

India is an attractive and growing market for shariah-compliant financial services. Therefore, the purpose of this article is to propose a systematic process for developing new shariah-compliant financial services for the growing number of Muslim customers in the big emerging market of India. This article is based on a longitudinal case study of service innovation employed by a multinational bank providing a diverse range of financial services to the Indian Muslim customers. The findings suggest that a structured new service development process must be used for developing new shariah-compliant financial services. Customer interaction during the service innovation is also important. This research is the first attempt to explore the development process of new shariah-compliant services in India. The findings of this research can be very useful to the managers of multinational financial institutions interested in marketing Islamic banking products and services in the burgeoning Indian market.
The object of mobile spatial data, the subject in mobile spatial research

With an estimated one billion smartphones producing over 5 petabytes of data a day, the spatially aware mobile device has become a near ubiquitous presence in daily life. Cogent, excellent research...
527. Improvement of Pre-Clinical Non-Human Primate Model for Pluripotent Stem Cell Based Therapies by Introducing Marker Genes in Safe Harbor Locus

Induced pluripotent stem cells (iPSCs) are being developed as sources for clinical cellular regenerative therapies, as well as valuable in vitro human disease models. Derivation of iPSCs from non-human primates (NHP) affords the opportunity to test the safety, feasibility and efficacy of proposed iPSC-derived cellular delivery in species with physiology, immunology and scale similar to humans. However, there is a need for stable and safe labeling methods for iPSCs and their differentiated progeny allowing analysis of survival, proliferation, tissue integration and biodistribution, in vitro and in vivo. Typically, marker genes have been inserted into target cells by transduction with randomly-integrating viral vectors. However, these methods raise concerns regarding genotoxicity and transgene silencing, particularly in pluripotent stem cells, limiting their utility for tracking and eventual clinical applications. Targeted integration into genomic “safe harbors” offer a promising alternative approach to mark target cells, potentially circumventing these issues. The adeno-associated virus integration site 1 (AAVS1) has been proposed as a suitable safe harbor for human cells, and we now investigate its utility in our rhesus macaque NHP iPSC model. We have efficiently knocked-in both a truncated CD19 (hΔCD19) marker gene a non-immunogenic and clinical relevant marker, or green fluorescent protein (GFP) at the homologous AAVS1 site in rhesus iPSCs (RhiPSCs) using the clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease 9 (CRISPR-Cas9) system. PCR and Southern blot analyses demonstrated highly efficient knock-in into the AAVS1 locus, with over one third of clones screened containing only targeted but not random integrations. (Table 1Table 1). Edited RhiPSC-GFP/hΔCD19 clones retained a normal karyotype and pluripotency - as shown by teratoma formation. Directed differentiation of these clones to neutrophils, hepatocytes or cardiomyocytes was not hindered by the knock-in of marker genes into the AAVS1 sites. Notably, transgene expression was stable in undifferentiated RhiPSCs and differentiated cell types derived from the RhiPSC (Figure 1Figure 1), in contrast to prior experience with viral vector delivery. We have established a computational platform to assess off-target effects of guide RNAs in the rhesus genome. Genetically marked RhiPSCs afford a unique opportunity to develop clinically relevant models for iPSC-based cell therapies.Table 1Summary of CRISPR-mediated gene editing in rhesus iPSCsOriginal iPSC cloneReporter geneClones with TI/Clones screened1Clones without RI/Clones with TI2ZG15-M11-10hΔCD194/42/8GFP14/145/9ZG32-3-4hΔCD19ND1/4GFPND2/4ZH26-HS41hΔ CD19ND1/4Total18/18(100%)11/29 (37.9%) View Table in HTML RI: random integration, TI; targeted integration, ND: not determined1based on by PCR analysis2based on Southern blot analysisView Large Image | Download PowerPoint Slide
Are coups good for democracy? A response to Miller (2016):

This article responds to “Reanalysis: Are coups good for democracy?” (Miller MK (2016) Reanalysis: Are coups good for democracy? Research and Politics 3(4): ) We make clear to readers that Miller (2016) re-reports findings that we originally reported in the Appendix to our original article. We then discuss the advantages and disadvantages of different estimators and re-state Miller’s main point with a visual presentation of how regime-case and country fixed effects estimators differ in this application.
Reactive force field simulation on thermal conductivities of carbon nanotubes and graphene

Abstract Carbon nanotubes (CNTs) and graphene are thought to be building bricks for next-generation thermal management devices due to their ultra-high thermal conductivities. However, in practical applications they do not exhibit their full potentials due to issues from interfaces, dopants, and functional groups. Thus, deep understanding of these effects on the thermal conductivities is needed. Molecular dynamics (MD) simulation can provide such insights into these material systems. However, prediction capability is limited by a narrow choice of chemical elements in traditional equilibrium MD potentials. Herein, non-equilibrium MD (NEMD) simulations were implemented to study the thermal conductivities of CNTs and graphene by using ReaxFF potentials (Reax-03, Reax-12, and Reax-15), all of which enable a wider choice of the element category. In the simulations, CNT and graphene have maximum lengths of 400 nm. The length-dependent thermal conductivities were studied in those systems. The ReaxFF potentials predicted higher thermal conductivities and longer phonon mean free paths than the traditional AIREBO potential. The geometry and location of G-peaks shown in the phonon density of states calculated by the Reax-03 and Reax-12 potentials were similar to the results obtained from the AIREBO potential. In contrast, a wider G-peak was obtained from the Reax-15 potential. The phonon dispersion curves based on each potential showed that Reax-03 and Reax-12 can predict accurate out-of-plane modes when compared with experiments. The Gruneisen parameters of the ZA mode based on the Reax-03 and Reax-12 potentials are smaller than those based on the AIREBO potential, indicating a lower anharmonicity of lattice vibrations. Radical distribution functions from the Reax-03 and Reax-12 potentials showed a higher lattice stiffness and longer phonon mean free paths (MFPs) than those obtained from the AIREBO potential. These results illustrate the capability of ReaxFF in predicting thermal conductivities of low dimensional carbon allotropes and their derivatives for advanced heat management.
Leukocyte and plasma activation profiles in chronically transfused patients with a history of allergic reactions

BACKGROUND Allergic transfusion reactions are drawbacks to the benefits of transfusion. Classically, allergic transfusion reactions depend on histamine release from mast cells or basophils, but other leukocyte subsets may also be important. Thus, we propose to better define the exact leukocyte subsets involved in allergic transfusion reactions. STUDY DESIGN AND METHODS The overall objective of the current study was to compare the activation of specific peripheral blood leukocyte subsets (monocytes, neutrophils, eosinophils, and basophils) in a cohort of 13 patients who received chronic transfusions and had a history of allergic transfusion reactions compared with a control group of patients who received chronic transfusions and had no history of allergic transfusion reactions. Leukocyte subsets were analyzed by flow cytometry at baseline and after red blood cell transfusion, and cytokine levels in platelet-free plasma collected at the same time points were measured by Luminex assay. RESULTS Flow cytometry and cytokine profiles before and after transfusion did not differ significantly between patients who did and did not have a history of allergic transfusion reactions (p > 0.05). However, post-transfusion samples from both groups showed a decrease in CD63 expression in basophils, monocytes, and eosinophils and a decrease in CD45 expression in all leukocyte subsets compared with pretransfusion samples. Interleukin 10 levels increased after transfusion in the group with a history of allergic transfusion reactions (p = 0.0469), and RANTES (regulated upon activation, normal T-cell expressed and secreted) was significantly decreased post-transfusion in all patients (p = 0.0122). CONCLUSION None of the leukocyte subsets from patients who had a history of allergic transfusion reactions significantly increased in activation either before or after transfusion. All leukocyte subsets from patients who did and did not have a history of allergic transfusion reactions decreased in their activation profile upon transfusion challenge.
Healthcare utilization, Medicare spending, and sources of patient distress identified during implementation of a lay navigation program for older patients with breast cancer.

Despite benefits for patients, sustainability of breast cancer navigation programs is challenging due to the lack of reimbursement for navigators. This analysis describes distress reported by breast cancer patients to navigators and the impact of navigation on healthcare utilization for older adults with breast cancer. We conducted a retrospective cohort study of Medicare administrative claims data and patient-reported distress assessments. The primary outcome was Medicare spending per beneficiary per quarter. Secondary outcomes included (1) the number of hospitalizations or ER visits in each quarter; (2) distress levels; and (3) causes of distress reported by patients to their navigators. A subset analysis was conducted for stage I/II/III versus stage IV patients. 776 navigated and 776 control patients were included in the analysis. The average age at diagnosis was 74 years; 13% of the subjects were African American; 95% of patients had stage I–III. Medicare spending declined faster for the navigated group than the matched comparison group by $528 per quarter per patient (95% CL −$667, −$388). Stage I/II/III navigated patients showed a statistically significant decline in Medicare spending, ER visits, and hospitalizations over time compared to the matched comparison group. No differences were observed for stage IV patients. Eighteen percent of patients reported moderate distress. Informational and physical distress were more common in late stage than in early-stage breast cancer. Lay navigation reduced healthcare utilization in older adults with breast cancer, with the greatest impact observed in early-stage breast cancer patients.
Sport governance as global governance: theoretical perspectives on sport in the international system

International sport governance is often described as both a significant and unique part of international politics. Simultaneously, proponents of this view lament the lack of (especially academic) attention paid to international sport governance as a political phenomenon. In this essay, the author argues that remedying this problem requires an understanding of sport as a product of the international system, and that the existing system of transnational sport governance organisations should be studied in much the same way as other international governance institutions, such as the United Nations, the World Health Organization and the Organisation for Economic Cooperation and Development. This conceptualisation of international sport governance as an institution is used to demonstrate how paradigms and theoretical frameworks from the field of international relations (IR) can be usefully applied to international sport governance research. Integrating IR theory with sport governance research can enhanc...
Resilience Analysis of Top K Selection Algorithms

As the number of components in high-performance computing (HPC) systems continues to grow, the number of vehicles for soft errors will rise in parallel. Petascale research has shown that soft errors on supercomputers can occur as frequently as multiple times per day, and this rate will only increase with the exascale era. Due to this frequency, the resilience community has taken an interest in algorithmic resilience as a means for reliable computing in faulty environments. Probabilistic algorithms in particular have generated interest, due to their imprecise nature and ability to handle incorrect guesses. In this paper, we analyze the intrinsic resilience of a probabilistic Top K selection algorithm to silent data corruption in the event of a single event upset. We introduce a new paradigm of analytically quantifying an algorithm's resilience as a function of its inputs, which permits a precise comparison of the resilience of competing algorithms. In addition, we discuss the implications of our findings on the resilience of probabilistic algorithms as a whole in comparison to their deterministic counterparts.
Convection in the Labrador Sea: Community Modeling Effort (CME) Results

Abstract Results from the World Ocean Circulation Experiment Community Modeling Effort are compared with observations to study the effects of convective parameterization in the Labrador Sea. The results show that the model boundary conditions have a strong influence on the relative intensity of convection in the northern part of the Labrador Sea, producing an anomalous cross current at about 60° N. Cross sections from the coast of Labrador and south of Greenland show overall agreement, but are considerablydifferent in some areas. In particular, the cold, North Atlantic Bottom Water is not modeled correctly and the model exhibits overly warm, salty surface water south of CapeFarewell. Convection in the model is in general too widespread and does not extend to theproper depth.
Traditional Femininity Versus Strong Black Women Ideologies and Stress Among Black Women

The construct of femininity has typically been conceptualized from a Eurocentric perspective as traditional femininity ideology (TFI). This hegemonic femininity construction might not be fully appl...
Frederick Douglass Patterson (1901–1988)

This chapter highlights the accomplishments and historical significance of Frederick Douglass Patterson who served as President of Tuskegee University and established the United Negro College Fund. The chapter also offers a critical analysis of the role Dr. Patterson had in contributing to the growth and development of education in the African American community, especially as it relates to education policies and practices in twentieth-century America.
22 Renal complications in LVAD and heart transplant patients

Renal dysfunction remains a primary determinant of both short- and long-term outcomes following heart transplantation (HTx) and ventricular assist device (VAD) implantation.1 2 Challenging to the assessment of candidacy for advanced heart failure (HF) therapies is the ability to distinguish intrinsic parenchymal renal disease from reversible cardiorenal disease. Patients with haemodynamically mediated renal failure may recover kidney function once renal perfusion is restored following HTx or VAD surgery. Chronic hypoperfusion, however, can lead to progressive structural lesions that may not improve despite correction of underlying haemodynamic abnormalities. In patients undergoing kidney biopsy as part of their HTx evaluation, there was poor correlation between eGFR and the extent of tubular atrophy and interstitial fibrosis.3 Prolonged elevation of serum creatinine (SCr) levels suggest but do not prove irreversibility and SCr in isolation is unlikely the best biomarker to determine transplant candidacy in this clinical setting. Reasons for SCr elevation in HF including pharmacotherapies such as renin-angiotensin-aldosterone system antagonists which lead to SCr elevations unrelated to underlying renal dysfunction. Additionally, patients with HF are frequently malnourished with muscle wasting, in which case SCr levels may be misleading. Baseline proteinuria is associated with poor post-operative outcomes in LVAD recipients and is an easily measurable biomarker that can further help to risk stratify patients in advance of VAD surgery.4 While absolute thresholds of risk are difficult to define, if eligible for dual organ transplant, advanced HF patients with GFR References Kirklin JK, Naftel DC, Pagani FD, Kormos RL, Stevenson LW, Blume ED, Miller MA, Baldwin JT, Young JB. Sixth INTERMACS annual report: a 10,000-patient database. J Heart Lung Transplant 2014;33:555–564. Erratum in: J Heart Lung Transplant2015;34:1356. Hong KN, Merlo A, Chauhan D, Davies RR, Iribarne A, Johnson E, Jeevanandam V, Russo MJ. Evidence supports severe renal insufficiency as a relative contraindication to heart transplantation. J Heart Lung Transplant 2016;35:893–900. Labban B, Arora N, Restaino S, Markowitz G, Valeri A, Radhakrishnan J. The role of kidney biopsy in heart transplant candidates with kidney disease. Transplantation 2010;89:887–893. Topkara VK, Garan AR, Fine B, Godier-Furnemont AF, Breskin A, Cagliostro B, Yuzefpolskaya M, Takeda K, Takayama H, Mancini DM, Naka Y, Colombo PC. Myocardial recovery in patients receiving contemporary left ventricular assist devices: results from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS). Circ Heart Fail 2016;9. pii: e003157. Kilic A, Grimm JC, Whitman GJ, Shah AS, Mandal K, Conte JV, Sciortino CM. The survival benefit of simultaneous heart-kidney transplantation extends beyond dialysis-dependent patients. Ann Thorac Surg 2015;99:1321–1327.