Polycystic Kidney Disease

1. Jacques Benun, MD 2. Carol Lewis, MD 1. Hasbro Children's Hospital Providence, RI Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD): The New Horizon For Children Who Have DPKD . Rizk D, Chapman A. Pediatr Nephrol. 2008;23 :1029– 1036[OpenUrl][1][CrossRef][2][PubMed][3] Autosomal Recessive Polycystic Kidney Disease . Zerres K. Clin Investig. 1992;70 :794– 801[OpenUrl][4][PubMed][5][Web of Science][6] Familial Juvenile Nephronophthisis. Konrad M, Saunier S, Calado J, et al. J Mol Med. 1998;76 :310– 316[OpenUrl][7][CrossRef][8][PubMed][9] Congenital Nephropathies and Uropathies. Becker N, Avner E. Pediatr Clin North Am. 1995;42 :1324– 1328[OpenUrl][10] Polycystic kidney disease is the most common hereditary renal malformation. Many malformation syndromes are associated with renal cysts, the primary renal diseases being autosomal dominant polycystic kidney disease (ADPKD), autosomal recessive polycystic kidney disease (ARPKD), and juvenile nephronophthisis (NPH). ADPKD is the most common inherited renal disease, affecting 1 in 800 live births in the United States. The genetic defect is present in utero, but most affected children are asymptomatic. The usual onset of clinical manifestations occurs from the third through … [1]: {openurl}?query=rft.jtitle%253DPediatric%2Bnephrology%2B%2528Berlin%252C%2BGermany%2529%26rft.stitle%253DPediatr%2BNephrol%26rft.aulast%253DRizk%26rft.auinit1%253DD.%26rft.volume%253D23%26rft.issue%253D7%26rft.spage%253D1029%26rft.epage%253D1036%26rft.atitle%253DTreatment%2Bof%2Bautosomal%2Bdominant%2Bpolycystic%2Bkidney%2Bdisease%2B%2528ADPKD%2529%253A%2Bthe%2Bnew%2Bhorizon%2Bfor%2Bchildren%2Bwith%2BADPKD.%26rft_id%253Dinfo%253Adoi%252F10.1007%252Fs00467-007-0706-9%26rft_id%253Dinfo%253Apmid%252F18259779%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1007/s00467-007-0706-9&link_type=DOI [3]: /lookup/external-ref?access_num=18259779&link_type=MED&atom=%2Fpedsinreview%2F30%2F10%2Fe78.atom [4]: {openurl}?query=rft.jtitle%253DThe%2BClinical%2Binvestigator%26rft.stitle%253DClin%2BInvestig%26rft.aulast%253DZerres%26rft.auinit1%253DK.%26rft.volume%253D70%26rft.issue%253D9%26rft.spage%253D794%26rft.epage%253D801%26rft.atitle%253DAutosomal%2Brecessive%2Bpolycystic%2Bkidney%2Bdisease.%26rft_id%253Dinfo%253Apmid%252F1450634%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [5]: /lookup/external-ref?access_num=1450634&link_type=MED&atom=%2Fpedsinreview%2F30%2F10%2Fe78.atom [6]: /lookup/external-ref?access_num=A1992JM59100013&link_type=ISI [7]: {openurl}?query=rft.jtitle%253DJournal%2Bof%2Bmolecular%2Bmedicine%2B%2528Berlin%252C%2BGermany%2529%26rft.stitle%253DJ%2BMol%2BMed%26rft.aulast%253DKonrad%26rft.auinit1%253DM.%26rft.volume%253D76%26rft.issue%253D5%26rft.spage%253D310%26rft.epage%253D316%26rft.atitle%253DFamilial%2Bjuvenile%2Bnephronophthisis.%26rft_id%253Dinfo%253Adoi%252F10.1007%252Fs001090050222%26rft_id%253Dinfo%253Apmid%252F9587065%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [8]: /lookup/external-ref?access_num=10.1007/s001090050222&link_type=DOI [9]: /lookup/external-ref?access_num=9587065&link_type=MED&atom=%2Fpedsinreview%2F30%2F10%2Fe78.atom [10]: {openurl}?query=rft.jtitle%253DPediatr%2BClin%2BNorth%2BAm.%26rft.volume%253D42%26rft.spage%253D1324%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx