cssi/SciSciGPT-SciSciNet huggingface dataset:
Efficiency improvement opportunities for televisions in India: implications for market transformation programs

Televisions (TVs) account for a significant portion of residential appliance electricity consumption in India, and TV shipments in India are expected to continue to increase. We assess the market trends in the energy efficiency of TVs that are likely to occur without any additional policy intervention and estimate that TV efficiency will likely improve with saving potential of 6 terawatt-hours (TWh) per year in 2020, compared to today’s technology. We discuss various energy-efficiency improvement options and evaluate the cost-effectiveness of three of them, at least one of which improves efficiency by at least 20 % cost-effectively beyond these ongoing market trends. We provide insights for policies and programs that can be used to accelerate the adoption of efficient technologies to capture the cost-effective energy savings potential from TVs which we estimate to be 3.4 TWh per year in 2020.
Thermal Lens Measurements in Liquids on a Submicrosecond Time Scale

The use of the thermal lens method is shown to be quite suitable for kinetic studies of quenching on a submicrosecond time scale. The lower limit of time resolution that can be achieved is determined by the acoustic transit time, τa, in the medium. A thermal lens signal with a 100-ns time constant due to the quenched triplet state of benzophenone is readily measured. The thermal lens method is superior to the photoacoustic (PA) method in the breadth of the accessible time range, and in the significantly fewer measurements required to obtain accurate data, including no requirement for a reference sample; it is also less sensitive to geometrical and laser power requirements than is the PA method.
A Mössbauer spectroscopic investigation of a series of Boron-Capped iron II clathrochelates

Abstract A series of boron-capped iron (II) clathrochelates has given excellent Mossbauer intensities for room and liquid nitrogen temperatures. The quadrupole splittings for these clathrochelates decrease slightly between room and liquid nitrogen temperatures, having values between 0.4 and 1.2 mm/sec. The isomer shifts are close to 0.0 mm/sec relative to α-Fe. This is an indication of iron (II) in a low and/or intermediate spin state. While the isomer shift differences are nominal, the quadrupole splittings correlate with the size of the atom or atomic group at the boron site and the distortion of the complex from a trigonal prismatic structure. There is evidence of a phase change for two of the complexes (Fe(DMG) 3 (BH) 2 and Fe(DMG) 3 (BF) 2 between room and liquid nitrogen temperatures.
Organ-specific autoantibodies in children with common endocrine diseases.

Sera from 438 children were examined for autoantibodies to thyroid microsomes, thyroglobulin, pancreatic islet cells, gastric parietal cells, and adrenocortical cells by indirect hemagglutination and immunofluorescence techniques. A modification of the indirect hemagglutination technique allowed specific detection of low titers of antithyroidal antibodies. The subjects included a control group (117) with no known autoimmune disease, and children with disorders of the thyroid (88), insulin-dependent diabetes mellitus (201), Turner syndrome (24), and Addison disease (8). A subject's age at the time of disease onset and the race and sex were correlated with the prevalence of autoantibodies. The coincidence of autoantibodies to components of the thyroid with autoantibodies to gastric parietal cells was increased in children with disorders of the thyroid (94%, 18/19) over that observed in diabetes (29%, 4/14), Turner syndrome (0%), or Addison disease (0%), perhaps indicating different genetic propensities for the development of parietal cell antibodies in these groups. Islet cell antibodies were not found in subjects with Turner syndrome, nor were they more prevalent in white or black subjects with diabetes. The incidence of organ-specific autoantibodies in individuals without overt clinical disease may reflect an altered immunologic state that will lead eventually to autoimmune disease. Islet cell antibodies decline in prevalence in diabetes, whereas thyroid antibodies in disorders of the thyroid do not; this may reflect differences in the pathogenesis of these common autoimmune endocrine disorders in children.
Evaluative verbalization and delay maintenance behavior in children

Abstract An experiment is presented which examined the influence of verbalizations on children's tendencies to postpone immediate gratification in terms of increased delayed reward. Children's verbalizations were varied in terms of their evaluative valence and whether they focused upon the reward itself or the delay task. During a delay task children in experimental groups periodically verbalized evaluative statements that were either positive (I like …) or negative (I don't like …) and which focused upon either the reward itself (… the tokens) or the delay behavior (… to wait). Children who focused on reward, under conditions of either positive or negative evaluation, postponed immediate gratification less than control subjects who made no verbalization. Children who evaluated delay behavior positively postponed immediate gratification longer than silent subjects, though children who negatively evaluated delay behavior did not differ from subjects who did not verbalize. The results are interpreted in terms of the influence of evaluative valence and focus as parameters of plans for delay behavior.
Rapid method for determination of plasma fibrinogen.

SummaryA method is presented for rapid and, under certain conditions, accurate determination of plasma fibrinogen level. The method correlates well with standard tyrosine technic. This method should find its greatest use in rapid determination of plasma fibrinogen level in hemorrhagic catastrophes and especially in hemorrhagic accidents of pregnancy.
Sponsorship and follow-up effects on response quality of mail surveys

Abstract This paper reports the results of an investigation of response quality in a mail survey. Survey sponsorship (university versus consulting firm) was evaluated in relation to the classification of the respondent (university alumni versus general public) on the dependent variable. In addition, response quality of the follow-up questionnaire was compared to that of the initial mailing. The findings revealed that there were differences in response quality between the initial and follow-up mailing. No differences were found in response quality for the four experimental conditions within the initial mailing, but differences were found within the follow-up mailing. Interpretations of the findings are discussed and implications for further research are presented.
Cultural influences on national rates of innovation

Abstract The purpose of this research was to examine the effect of the cultural values of individualism, power distance, uncertainty avoidance, and masculinity on national rates of innovation in 33 countries in 1975 and 1980. The study found that rates of innovation are most closely associated with the cultural value of uncertainty acceptance, but that lack of power distance and individualism also are related to high rates of innovation. This research suggests that nations may differ in their rates of innovation because of the cultural values of their citizens. These findings have important implications for managers and policy-makers. First, culture matters. Countries may not be able to increase their rates of innovation simply by increasing the amount of money spent on research and development or industrial infrastructure. They also may need to change the values of their citizens to those that encourage innovative activity. This concept, in turn, suggests that national rates of innovation are driven by more fundamental forces than economic conditions, and that societal change may be necessary to make less innovative societies more innovative. Second, the values associated with high national rates of innovation are those that many scholars have long argued are important at the firm level. An acceptance of uncertainty appears to be necessary, probably because innovation requires a tolerance for risk and change. Individualism seems to be important, perhaps because of its association with autonomy, independence, and freedom. Lack of power distance appears important, perhaps reflecting the role that tolerance of change in the social order and distribution of power play in the innovation process. Third, the study indicates that the strength of the relationship between innovation and two cultural values—individualism and lack of power distance—were stronger in 1975 than in 1980, suggesting, perhaps, that these values are becoming less important in spurring the innovation process. This finding supports the anecdotal evidence that many collectivist and hierarchical Asian nations are becoming more innovative. Fourth, this study shows that per capita income is a more important economic variable than industrial structure in determining national rates of innovation. This finding confirms previous work that has shown that as nations become wealthier, they become more innovative. The reason may be that wealthier countries have more demand for innovations, both because innovations are often laborsaving, and because wealthier nations have greater demand for new and differentiated consumer goods.
Invited Commentary: Trends in Coronary Heart Disease Mortality—Location, Location, Location

The well-documented decline in coronary heart disease (CHD) mortality in the United States of approximately 3 percent per year over the past 30 years is one of the most remarkable developments in improving public health in the modern era. Determining the relative contribution of treatment versus primary prevention in achieving this decline is an important medical and epidemiologic issue. This endeavor is not about assigning credit but is a discovery of ways to accelerate the decline and reach those segments of the population that have not yet benefited from the reduction. In real estate, the maxim “location, location, location” is a commentary on the preeminence that setting has in determining the value of a home. Likewise, the “location” of CHD deaths in the community—in-hospital or out-ofhospital—helps elucidate the role and the potential of medical treatment versus primary prevention in reducing CHD death. Temporal trends in in-hospital deaths often are associated with medical care, whereas trends in out-ofhospital events are best associated with primary prevention. This is helpful thinking, especially when combined with information about prior history of heart disease. For example, the rate of sudden cardiac death (SCD) outside of hospitals among persons with no prior history of heart disease is a target of primary prevention and risk factor management more so than medical treatment. Conversely, preventing a fatal outcome for a hospitalized patient with CHD involves medical and/or surgical intervention in the context of disease severity, which is related to both medical treatment and primary prevention. As such, trends in these types of events are often considered an indication of the success of primary prevention and treatment innovation.
Adherence to the 2010 Dietary Guidelines for Americans and the Relationship to Adiposity in Young Women

Abstract Objective To determine the relationship between adherence to the 2010 Dietary Guidelines for Americans and adiposity in young women with and without statistical adjustment for physical activity (PA). Methods Participants included 324 young women (aged 17–25 years). The researchers measured dietary intake using the Dietary History Questionnaire and determined diet quality using the 2010 Healthy Eating Index (HEI-2010). BOD POD (Cosmed, Rome, Italy, 2006) and accelerometry were used to assess body fat and PA, respectively. Results Women in the top quartile of HEI-2010 had significantly lower percent body fat than women in the lowest 3 quartiles (F = 3.36; P = .03). Controlling for objectively measured PA weakened this relationship by 20%. These young women (top quartile of HEI-2010) also had 0.37 odds (95% confidence interval, 0.16–0.85) of having body fat > 32%. Conclusions and Implications Young women whose diets most closely meet the 2010 Dietary Guidelines for Americans have lower adiposity.
Human Experiments and National Security: The Need to Clarify Policy

On September 4, 2001, press reports indicated that the Defense Intelligence Agency of the U.S. Department of Defense (DOD) planned to reproduce a strain of anthrax virus suspected of being held in Russian laboratories. According to the same reports, the Central Intelligence Agency (CIA), under the auspices of Project Clear Vision, is engaged in building replicas of bomblets believed to have been developed by the former Soviet Union. These small bombs were designed to disperse biological agents, including anthrax. Government attorneys were said to be confident that, because these projects were designed to develop defensive measures, they were not in violation of the 1972 Biological and Toxin Weapons Convention.
Locomotory patterns, spatiotemporal organization of exploration and spatial memory in serotonin transporter knockout mice.

Abstract Serotonin transporter knockout (SERT−/−) mice are extensively used as a genetic model of several neuropsychiatric disorders, and consistently display anxiety-like behaviors and inactivity in different tests. To better understand how these mice organize their behavior, we assessed the open field and elevated plus maze spatiotemporal patterning of activity in adult male SERT wild type (+/+), heterozygous (+/−) and −/− mice on C57BL/6J genetic background using new videotracking and analytic procedures. In addition, we analyzed their spatial memory, assessing within- and between-trial habituation, and examined specific motor characteristics of their movement in these two tests. In the open field test, SERT−/− mice showed reduced vertical exploration throughout the arena, reduced central (but not peripheral) horizontal exploration, unaltered within-trial habituation, and slightly poorer between-trial habituation for horizontal activity. In the elevated plus maze, SERT−/− mice demonstrated anxiety-like avoidance of open arms, hypoactivity, as well as unaltered within-trial and between-trial habituation (except for poorer between-trial habituation of total horizontal activity). In both tests, SERT−/− mice showed greater prevalence of horizontal over vertical dimension of their exploration in the areas protected by the walls (open field periphery, plus maze closed arms), but not in open aversive areas, such as the center of the open field or center or open arms of the maze. In both arenas, SERT−/− mice consistently displayed increased turning behavior, potentially representing a perseverance-like phenotype or aberrant spatial strategies in novel environments. Overall, using a fine-graded behavioral analysis in two different novelty tests, this study revealed alterations in motor and spatiotemporal patterning of activity in SERT−/− mice. Given the relevance of exploratory strategies to human personality traits and brain disorders, our data may be useful for developing further neurobehavioral models using these mice.
Effects of Chilling Method on the Sensory, Chemical and Cooking Characteristics of Ground Beef Patties

Hot-boned beef (excised 90 min postmortem) was chilled either by mixing coarse ground beef with CO(2) snow or by immersing ground beef chub packs in a brine chiller (-2 degrees C). Hamburger patties were prepared from both hot and cold-boned chub packed, coarse ground beef after 0, 7, 14, and 21 days of storage (0 degrees C). Microbiological quality of the hot-boned ground beef was either superior or equal to that of the control. Purge present in all the chub packs after 21 days of storage was 1.0%. Patties prepared from CO(2) chilled ground beef were more tender than control patties. Patties prepared from brine-chilled ground beef had greater cooking losses than patties prepared from cold-boned ground beef.
Deployment Strategy for Mobile Robots with Energy and Timing Constraints

Mobile robots usually carry limited energy and have to accomplish their tasks before deadlines. Examples of these tasks include search and rescue, landmine detection, and carpet cleaning. Many researchers have been studying control, sensing, and coordination for these tasks. However, one major problem has not been fully addressed: the initial deployment of mobile robots. The deployment problem considers the number of robots needed and their initial locations. In this paper, we present a solution for the deployment problem when robots have limited energy and time to collectively accomplish coverage tasks. Simulation results show that our method uses 26% fewer robots comparing with two heuristics for covering the same size of area.
Waveform Diversity Based Ultrasound System for Hyperthermia Treatment of Breast Cancer

In this letter, we present a new waveform-diversity-based ultrasound hyperthermia technique for the treatment of breast cancer. Waveform diversity offers a new paradigm for beampattern design. By choosing a proper covariance matrix of the transmitted waveforms under the uniform elemental power constraint, the ultrasound system can provide a focal spot matched to the entire tumor region, and meanwhile, minimize the impact to the surrounding healthy breast tissues. As shown in our 2-D numerical simulations, this method has better acoustic power deposition than the existing methods, and can provide the necessary temperature gradients required for the effective hyperthermia treatment of breast cancer.
Imidacloprid in Melon Guttation Fluid: A Potential Mode of Exposure for Pest and Beneficial Organisms

ABSTRACT ELISA techniques were used to detect imidacloprid in guttation fluid of young cantaloupe plants in Arizona. Imidacloprid was detected at up to 4.1 µg/ml (ppm) in a coincidental guttation collection 3 d after a top label rate soil application and at 37 µg/ml one d after a separate top label rate soil application study. These imidacloprid titers exceed reported median oral toxicities for several insect species by factors of 10 or more. Pesticides in guttation fluid are a relatively unexplored route of exposure for both pest and beneficial insects, and could represent an important risk for both of these groups in guttation-prone environments.
France Debates International Student Fees

The question of international students’ tuition fees has sparked debates in many of the European welfare states. One of the latest countries to face such a debate was France, where the matter is complicated by the African origin of half of the mobile students. This article looks at the French context to provide insights on the questions and concerns that the establishment of such policies should raise.
Hybridization of RNA from the mouse spleen and low density reiterative DNA.

Minor fractions of nuclear DNA which reassociate rapidly have been identified in many eucaryotes; they may or may not have buoyant densities differing from the bulk of the DNA. They contain DNA sequences of varying degrees of repetition frequency.In this report, we describe afraction of reiterative DNA which Results in dicate that a formed hybrids with RNA from mouse spleens. fraction of mouse splenic RNA undergoing relatively rapid synthesis and deqradation formed molecular hybrids w i t h DNA sequences of intermediate repetition frequency.
Optimal Planning for Urban Storm Drainage Systems

A watershed in an urban area may be partitioned into subbasins, each of which is a tributary to a downstream subbasin or to a receiving water body. The planning of a storm drainage system for such a watershed according to the requirements of Section 208, PL 92-500, can be efficiently accomplished by coordination of the interactions among the subbasins. A model for these interactions is presented and implemented in the urban storm drainage planning model URBDRAIN. The planning variables in the model are maximum conveying capacities of the drainage network, placement and size of detention storage facilities, and size of a central treatment facility. A two-level optimization solution procedure is shown which provides minimal-cost values for the planning variables. An example application is shown for a medium size community in Indiana.
Do We Need a VAT to Solve Our Long-Run Budget Problems?

The U. S. federal budget is on an unsustainable path. Three programs – Social Security, Medicare, and Medicaid constitute about one-half of spending and are growing faster than tax revenues and the economy. It is hard to imagine any solution to the problem that does not require some combination of tax increases and spending restraint. If taxes are to be increased, there are three options: rates can be increased in the current system; there can be a fundamental, revenue raising tax reform; or a brand new tax, such as a Vat may be imposed. The first option would be extremely inefficient and inequitable and the second would be very difficult politically. That leaves the possibility of a Vat which would be especially likely if reform has to take place in the midst of a budget crisis.
Axillary and Brachial Vessels

Penetrating injuries to the axillary and brachial vessels are fairly uncommon [1–5]. As with all traumatic injuries, prompt diagnosis and rapid repair provide the best outcomes. A thorough physical examination looking for any “hard” or “soft” signs of vascular injury will identify most injuries. Detailed neurological examination should be performed because of the proximity of these vessels to the branches of the brachial plexus. If an arterial injury is diagnosed on clinical ground, then operative intervention should be performed without further delay. If the physical examination is unrevealing and a clinical suspicion for vascular injury remains, then additional studies such as duplex ultrasonography or CT angiography should be performed. An understanding of the vascular anatomy and the relationships of key structures is critical for any operation, particularly in the emergency setting where anatomy is often distorted and time is of the essence.
15 Cognitive Components of the Event-Related Brain Potential: Changes Associated with Development

This report addresses some aspects of the relationship between normal development and cognitive components of event-related brain potentials (ERPs). It includes a description of the ERP components which have been associated with cognitive processes in normal infants, children and adolescents and a description of the way that these components might be changing with development. Also presented are some of the suggestions that researchers have made about the cognitive correlates of these components.
On a Family of Generalized Conchoids

(1959). On a Family of Generalized Conchoids. The American Mathematical Monthly: Vol. 66, No. 10, pp. 843-849.
Hidden effects of mouse chow.

![Figure][1] PHOTO: RAMA/WIKIMEDIA COMMONS In her 3 October News Features “The littlest patient” (p. [24][2]) and “Hope in a mouse” (p. [28][2]), J. Couzin-Frankel discusses the utility of mouse genetic cancer models for testing the efficacy of chemotherapeutic drugs [also discussed
Stabilization of Urinary 3-Hydroxyanthranilic Acid by Oral Administration of L-Ascorbic Acid.

SummaryA method is presented for the stabilization of urinary 3-hydroxyanthranilic acid (3-HOA) to enable the acquisition of more reliable data concerning the urinary excretion of 3-HOA by patients with tumors of the urinary bladder. The data show that significant amounts of 3-HOA can decompose in urine samples of some tumor patients if such samples are allowed to incubate at 37°C for 6 hours, and that the presence of high levels of L-ascorbate in such samples inhibits this decomposition.
Abstract 4878: The fallopian tube is the origin of high-grade serous ovarian carcinomas in a mouse model

Ovarian cancer is a lethal disease primarily because it is often not detected until it spreads beyond the female reproductive tract. Early detection is thus the key to successful intervention in ovarian cancer. Yet it is not known how this cancer arises and metastasizes. In the last decade, new evidence has challenged the dogma that the ovary is the main source of these cancers. The fallopian tube has been proposed instead as the primary origin of high-grade serous ovarian cancer _ the subtype causing 70% of ovarian cancer deaths. To understand the origin and early progression of this serous cancer, we have generated double knockout (DKO) mice by conditionally disabling in the reproductive tract two critical genes _ Dicer, an essential gene for microRNA synthesis, and Pten, a tumor suppressor that negatively regulates the PI3K pathway. These DKO mice develop high-grade serous carcinomas that arise from the fallopian tube. These high-grade serous cancers spread to engulf the ovary and then extensively metastasize throughout the abdominal cavity, causing ascites and killing 100% of the mice by 13 months. This is the first mouse model demonstrating that the fallopian tube is capable of initiating and developing high-grade serous carcinomas with similar clinical manifestations shown in the human serous ovarian carcinomas. Intriguingly, analyzing these DKO tumors at early time points also reveals that these epithelial cancers begin in the stroma of the fallopian tube, suggesting that the cancers arise through a mesenchymal-to-epithelial transition (MET) _ a novel mechanism of carcinoma initiation. This study thus presents a new paradigm for the origin and initiation of deadly high-grade serous ovarian cancer. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 4878. doi:1538-7445.AM2012-4878
Microwave digest-atomic fluorescence spectrometry for the determination of selenium in health food

[Objective]To established a method for the determination of selenium in health food by atomic fluorescence spectrometry with microwave digestions.[Methods]Optimizing the test condition,the sample was determined for selenium in health food by atomic fluorescence spectrometry.[Results] Linear range for the determination was between 10. 0 μg / L to 50. 0 μg / L. The detection limits was 3. 6 μg / kg. The relative standard deviation( RSD) was less than 5%. The recoveries were 92. 0%-102. 5%.[Conclusion]The method is simple,accurate and precise. It is suitable for the determination of Sselenium in health food.
Detection of activating MAP2K1 mutations in atypical hairy cell leukemia and hairy cell leukemia variant.

Hairy cell leukemia variant (HCLv) is a rare B-cell lymphoproliferative disorder that resembles classical hairy cell leukemia (HCLc) histologically but is immunophenotypically and clinically distin...
CHOLINE AVAILABILITY - CHOLINE HIGH AFFINITY TRANSPORT AND THE REGULATION OF ACETYLCHOLINE SYNTHESIS

The use of precursor-loading with choline as a therapeutic modality raises the question of whether the plasma levels of choline directly regulate the synthesis of (ACh) in brain. In this chapter, the issues of choline availability and the transport of choline by cholinergic nerve endings in the regulation of (ACh) formation will be discussed. Data are presented which suggest that under normal physiological conditions brain ACh levels and turnover are not regulated by the levels of free choline in plasma and that the physiologic regulatory step in ACh synthesis is the high affinity uptake of choline by cholinergic nerve endings.
Taxonomy of Oribatid Mites — Retrospect and Prospect

Ross (1971) considers systematics as the oldest of the sciences because it began with man’s lingual classification of things in his experience. Even though classification is arbitrary, biosystematics is an attempt to determine what to classify in nature, comprising both speciation — a natural process, and phylogeny — an artificial fabrication of the human mind subject to varying opinions and personal interpretations. In his view, taxonomy, biosystematics and phylogeny must be modified as new data and interpretations are disclosed.
BotTracer: Bot user detection using clustering method in RecDroid

RecDroid is a smartphone permission management system which provides users with a fine-grained real-time app permission control and a recommendation system regarding whether to grant the permission or not based on expert users' responses in the network. However, in such a system, malware owners may create multiple bot users to misguide the recommendation system by providing untruthful responses on the malicious app. Threshold-based detection method can detect malicious users which are dishonest on many apps, but it cannot detect malicious users that target on some specific apps. In this work, we present a clustering-based method called BotTracer to finding groups of bot users controlled by the same masters, which can be used to detect bot users with high reputation scores. The key part of the proposed method is to map the users into a graph based on their similarity and apply a clustering algorithm to group users together. We evaluate our method using a set of simulated users' profiles, including malicious users and regular ones. Our experimental results demonstrate high accuracy in terms of detecting malicious users. Finally, we discuss several clustering features and their impact on the clustering results.
Imatinib Plus Vincristin & Prednisolone Induces Complete Remission and Prolonged Survival in Elderly Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Patients.

Abstract Introduction: Acute lymphoblastic Leukemia (ALL) in elderly patients (50yrs or older) carries a poor prognosis. In survival studies using in variety of therapeutic regimens. This may be because of relatively high frequency of the Philadelphia chromosome (Ph). With the advent of dose intensive chemotherapy regimen such as hyper CVAD (Fractionated Cyclophosphamide, Vincristin, Doxorubicin, Dexamethasone) overall survival has not improved. The aim of our study was to see the effectiveness of Imatinib plus Vincristin & Prednisolone in Philadelphia Chromosome positive in elderly acute lymphoblastic leukemia patients. Material & Methods: During period from January 2006 December 2006 we selected 10 consecutive elderly (more than 50yrs) Ph+ ALL patients in the haemato-oncology department Netaji Subhash Chandra Bose Cancer Research Institute. There were 4 males & 6 females. The median age of the patient was 64years (range 51 to 77yrs). All patients were started with Imatinib mesylate (Natco pharma) 400mg daily. Prednisolone was given 40mg /m2 over 6weeks & followed by 2weeks tapering dose. Vincristin was given 2mg/m2 weekly for 6weeks. All patients were evaluated by bone marrow and molecular testing done every 3monthly for 1year then 6monthly. Result: All patients (100%) obtained complete haematological & partial molecular response at 3month. Three patient (30%) achieved complete molecular response at 9month. With median follow-up of 8months (range 6–15months) the disease free survival and overall survival were 80% & 90% respectively. Most of the induction treatment was done as OPD basis, no hospitalization required. The therapy was tolerated well. Conclusion: We concluded that Imatinib plus Vincristin & Prednisolone is a feasible, highly active protocol for elderly Philadelphia Chromosome positive acute lymphoblastic leukemia patients. It is well tolerated & associated with good quality of life.
Mesoscopic Analysis of Small Deformation in Heterogeneous Materials Using Voronoi Cell Finite Element Method

Engineering applications of functionally advanced heterogeneous materials like composites, alloy systems etc., have significantly increased in the recent years. This has resulted in a wide variety of analytical and numerical models for predicting effective material properties and evolution of microstructural state variables. Many advanced materials are additionally characterized by a considerable degree of randomness in their microstructural morphology. In these materials, effects of shapes, sizes, orientations, and locations of microscopic second phases, on deformation characteristics and material properties need to be studied extensively.
Thermal evaluation of water-based alumina nanofluid in an electronic heat sink application

An experimental study was conducted to investigate the thermal performance of a water-based Al2O3 nanofluid in an electronic heat sink application. Heat transfer tests were carried out using 20 nm alumina particles at a concentration of 5% by mass, and a coolant temperature ranging from 47 to 57 oC. The results were compared to a baseline case using deionized water as a coolant. Thermal conductivity and viscosity tests conducted on alumina nanofluids show both parameters increase with nanoparticles mass concentration. Alumina nanofluid with 5% nanoparticles mass concentration behaves as a shear thinning fluid. Tests conducted on an electronic heat sink show heat flux and coolant heat transfer coefficient increase with bulk mass flow rate. Compared to cooling by deionized water, the average increase in the heat transfer coefficient using water-based alumina nanofluid as a coolant was about 20%, while the average increase in heat flux was about 24%. An additional decrease in the heated wall cross-section temperature between 4.1 and 4.9 oC is also seen. For the same pumping power, the presence of nanoparticles in the base fluid is shown to have a significant effect on the increase in heat transfer coefficient.
SPOTLIGHT: Urban social movements, citizen participation, and trust networks

Urban social movements, whether on the left or the right of the political spectrum, typically share the aim of grass-roots empowerment and are, in Charles Tilly’s terms, trust networks. Their apogee in the United States and Western Europe occurred during the 1960s and 1970s. Subsequently their appearance has been episodic. So far they have not reversed the trend toward greater economic inequality that is structuring capitalist societies in the present epoch. Nevertheless, they have increased the level of democratic participation in governance, heightened environmental consciousness, and, in many places, produced higher levels of diversity and tolerance in social life.
‘I Have Come to Abolish Sacrifices’ (Epiphanius, Pan. 30.16.5): Re-examining a Jewish Christian Text and Tradition*

The Gospel of the Ebionites is a ‘text’ that only exists as fragments cited in and extrapolated from the heresiological writings of Epiphanius (Pan. 30). Like Recognitions 1.27–71, the Gospel of the Ebionites is one of a number of second- and third-century Jewish Christian sources, texts and traditions alleging that Jesus rejected animal sacrifice. In this article, I seek to review the history of research on this particular text and tradition and explore its significance as a case study in the use of non-canonical gospel traditions in New Testament studies.
Kinematic and Dynamic Properties of an Elbow Manipulator Mounted on a Satellite

The discussion in this paper is intended as an introduction to several topics treated in various forms or extensions in the other papers in this issue. Many applications of robots in space require the robot to manipulate a load mass that is not negligible compared to the satellite on which the robot is mounted. In such cases, the robot motion disturbs the position and attitude of the satellite, and this in turn disturbs the robot end-effector position. This implies that the robot joint angles that would normally be commanded to produce a prescribed robot end-effector position and orientation will result in missing the target. In this paper an overview is given of certain engineering problems arising from this phenomenon. The robot end-effector positioning problem is discussed for the two cases of the satellite attitude control system either off or on, and computation of the robot motion disturbances to the satellite is discussed. Shuttle Remote Manipulator System based examples are given.
Artin’s Primitive Root Conjecture

By now we have developed a lot of foundational material about the arithmetic of function fields. In this chapter we will put this material to work and give the beautiful proof, due to H. Bilharz, of E. Artin’s conjecture about primitive roots in function fields.
Acid–base directed supramolecular isomers of isophthalate based MOFs for CO2 adsorption and transformation

The ubiquitous [Cu(O2CR)4] paddlewheel molecular building block (MBB) is renowned for producing highly porous metal–organic frameworks (MOFs), yet some carboxylate based ligands can result in supramolecular isomers. We show that it is possible to manipulate the synthesis conditions to favor one isomer over another yielding MOFs with either an lvt or nbo topology. These isomers exist because the 4-connected paddlewheel MBB and isophthalate based ligand can form either a square grid or a Kagome lattice, where layers can join to give their respective framework topologies. Topology differences and accessible Cu(II) centers in isomers of [Cu2L]n were evaluated for their porous properties towards CO2 and their abilities to transform CO2 into value added chemicals under ambient conditions.
A Nondifferentiable Optimization Algorithm for the Design of Control Systems Subject to Singular Value Inequalities Over a Frequency Range

Abstract It has been known for some time that many control system design requirements can be expressed as differentiate inequalities. More recently, it has been shown that important structural properties such as robustness and low noise sensitivity can be expressed as nondifferentiable inequalities involving the singular values of a system or return difference transfer function matrix. This paper presents an optimization algorithm which permits all these constraints to be considered.
Arthroscopic Intramuscular Side-to-Side Repair of an Isolated Infraspinatus Tear

Abstract Intramuscular, full-thickness rotator cuff tears are uncommon and present a challenging clinical scenario for repair because traditional suture anchor or transosseous repair techniques are less feasible. The goal of repair is to achieve a tension-free reduction of both ends of the muscle to allow for adequate healing over time. Intramuscular tears of the infraspinatus specifically have rarely been reported. The clinical presentation of these patients can be challenging to interpret, and other causes of rotator cuff dysfunction, including compression to the suprascapular nerve, must be ruled out. In this Technical Note, we describe our technique for arthroscopic side-to-side suture repair of an isolated intramuscular infraspinatus tear.
Sex Words Used by Partners in a Relationship

Sanders (1978) asked college students what word, if any, they would use in a private conversation with their spouse or lover to refer to each other's genitalia and to the act of copulation. She found gender differences in words used to refer to male genitalia. Women were more likely to use scientific terms and less likely to use slang terms. Also, less variation was found in words used to refer to the act of copulation than in words used to refer either to male or female genitalia.The present study replicated Sanders's (1978) findings, but there were differences between students then and now. Students now were less likely to use scientific terms (e.g., penis and intercourse) and gross terms (e.g., cunt), and they were more likely to use no word at all to refer to their own or their partner's genitalia.The use of scientific terms was expected to increase and the use of no word at all to decrease after a class in Human Sexuality. This was clearly so for male genitalia. Use of “penis” did increase, and use o...
Stability analysis of anisotropic granular base layers in flexible pavements

Abstract The structural integrity of the unbound granular layers is of paramount importance for the design and analysis of multi-layer structures. The passage of slow moving vehicles in overload corridors can potentially compromise the stability of pavement foundations, and incur unforeseen costs to the travelling public. The likelihood of the destabilizing effect of overload traffic is more pronounced upon moisture intrusion due to infiltration or evapotranspiration. Additionally, due to the temperature and loading rate dependency of viscoelastic bituminous surface layers, the stresses transferred to the supporting granular layers will be more taxing in hot summer months. Therefore, it deems necessary to establish a mechanistic framework to characterize the synergistic influence of the moisture ingress and the parameters of the stress path to ensure the longevity of the granular layers. This research strives to bridge this gap by the development of an anisotropic protocol for the stability control of the granular layers. To achieve this objective, the anisotropic elasticity principles were employed to characterize the proximity of the applied stresses to the strength envelope of the particulate soils. The stability analysis presented in this research underscored the systematic error associated with isotropic characterization of granular layers. The numerical simulations showed that isotropic characterization of the base layer can potentially overestimate the structural capacity of unbound granular layers. This can manifest itself in premature failure of the pavement foundations. The findings of this research can be utilized by the pavement design industry and practitioners to mitigate costs associated with reconstruction and repair of pavements.
SV-Means: A Fast SVM-Based Level Set Estimator for Phase-Modulated Radar Waveform Classification

In this paper, a novel algorithm, SV-Means, is formulated for open set radar waveform classification. The approach extends the quantile one-class support vector machine (q-OCSVM) density estimation algorithm into a classification formulation with inspiration from k-means and stochastic gradient descent principles. Phase-modulated radar waveform data is used to compare the primal and dual q-OCSVM (configured for classification) to SV-Means to verify the algorithm's classification and rejection performance. SV-Means is also shown to be an effective open set classification algorithm and is compared to these other open set classifiers: 1-vs-set machine, W-SVM, PI-SVM, and probabilistic open space (POS)-SVM. The SV-Means algorithm proves to achieve similar, and some cases better, performance against comparable algorithms in a fraction of the training time (as the data records increase and, in the case of the q-OCSVM, level sets increase). The SV-Means open set algorithm is an attractive adaptive classification framework using any feature extraction approach including deep-learning architectures.
Botulinum Toxin Treatments for Sialorrhea Can Reduce Aspiration Related Hospitalizations (P03.027)

OBJECTIVE: We demonstrate that recurrent aspiration symptoms in patients with sialorrhea can be effectively treated with botulinum toxin. BACKGROUND: Sialorrhea is a common symptom in many primary neurologic disorders which can affect the health of patients. Injection of botulinum toxin into the submandibular and parotid glands has been shown to significantly reduce saliva production in multiple studies for diverse study populations. DESIGN/METHODS: Our study is a retrospective review of 4 patients with clinically significant sialorrhea who were referred for botulinum toxin treatment due to recurrent aspiration pneumonia. Two patients received botulinum toxin A and two patients received botulinum toxin B. Injections occurred every 3-4 months. Primary outcome was hospitalization due to aspiration pneumonia, pneumonitis or respiratory symptoms. RESULTS: Sialorrhea was subjectively reported to be improved for all patients. 2 patients9 outside medical records were available for analysis. Both patients had been treated with botulinum toxin A. Prior to treatment with toxin, patient 1 was hospitalized for respiratory symptoms an average of 17.8 days/year and patient 2 was hospitalized 25.6 days/year. Following treatment patient 1 was hospitalized 0.8 days/year and patient 2 was hospitalized 1.6 days/year. None of the patients reported adverse responses including dysphagia, respiratory insufficiency, or dry mouth. CONCLUSIONS: Botulinum toxin is a highly efficacious method for prevention of aspiration pneumonia due to sialorrhea with few adverse effects. Botulinum toxin therapy can both improve quality of life for patients and limit hospitalization associated costs. Disclosure: Dr. Lai has nothing to disclose. Dr. Lopez has received personal compensation for activities with O2 MedTech as a consultant.
Ethical considerations of sharing data for cybersecurity research

Governments, companies, and scientists performing cyber security research need reference data sets, based on real systems and users, to test the validity and efficacy of the predictions of a given theory. However, various ethical and practical concerns complicate when and how proprietary operational data should be shared. In this paper, we discuss hypothetical and actual examples to illustrate the reasons for increasing the availability of data for legitimate research purposes. We also discuss the reasons, such as privacy and competition, to limit data sharing. We discuss the capabilities and limitations of several existing models of data sharing. We present an infrastructure specifically designed for making proprietary operational data available for cyber security research and experimentation. We conclude by discussing the ways in which a new infrastructure, WINE, balances the values of openness, sound experimentation, and privacy by enabling data sharing with privacy controls.
Glial Precursor Cell Transplantation-Mediated Regeneration after Spinal Cord Injury Repair

Abstract Glial precursor cells (GPCs) have shown great promise for spinal cord injury (SCI) repair. They have been used to approach different therapeutic repair strategies in SCI. These include replacement of oligodendrocytes to promote remyelination of demyelinated and/or regenerated axons; providing a permissive substrate for axonal regeneration to overcome the intrinsic inhibition of surface molecules; and engendering host repair. The potential resources for human GPCs included the fetal central nervous system from abortion, human embryonic stem cells, induced pluripotent stem cells, or the direct reprogramming from somatic cells. The advantages and disadvantages of each cell resource are discussed. The great therapeutic potential of GPCs has been demonstrated in preclinical animal models for many human diseases, including SCI. However, there are several challenges that need to be overcome before the stem cell therapies can be translated to clinic benefiting the patients with SCI. These challenges are also discussed. Although obstacles need to be overcome for clinical application, the rapid progress in the stem cell field makes their use to treat SCI and other neurological disorders more feasible than ever.