cssi/SciSciGPT-SciSciNet huggingface dataset:
Treatment program operations and costs

This study investigates how average costs for an episode of care in outpatient drug-free (ODF) treatment relate to clinical intensity (length of stay and weekly counseling hours) and program structure (e.g., size, staffing), controlling for prices paid and selected clientele measures. Based on cost assessments from a naturalistic sample of 67 programs located across the United States (using the Treatment Cost Analysis Tool), robust regression techniques showed that programs having 10% longer treatment stays had episode costs 7% higher; those having 10% more weekly counseling hours per client had 4% higher episode costs. Other important factors included wages, amount of counselors' time conducting sessions, and serving more clients referred from the criminal justice system. The study provides valuable information on treatment program features that relate to costs. Most importantly, cost differences associated with longer stays or more intensive counseling protocols appear modest and may be justified by improved client outcomes.
Application of an integrated microchip system with capillary array electrophoresis to optimization of enzymatic reactions

In this work, a combination of complementary metal-oxide semiconductor (CMOS) microchip system with capillary array electrophoresis (CAE) is demonstrated as a system for optimizing conditions for enzymatic reaction. Dimethylacridinone (DDAO)-phosphate substrate and alkaline phosphatase conjugate were selected for the enzymatic reaction, which was applicable to the enzyme-linked immunosorbent assay (ELISA) technique. Laser-induced fluorometry with a miniature semiconductor laser was used to detect the enzymatic products. The speed of the enzymatic reaction between the DDAO-phosphate and the alkaline phosphatase conjugate was investigated as a function of reaction time. The microchip-CAE detection system could determine the pH condition and the concentration of enzyme that are suitable for rapid and low-cost analysis. This result shows the feasibility of using the microchip-CAE system for application to miniaturized screening systems.
Dactylaria gallopava , a Cause of Avian Encephalitis, in Hot Spring Effluents, Thermal Soils and Self-heated Coal Waste Piles

THE hyphomycetous fungus Dactylaria (= Diplorhinotrichum = Scolecobasidium) gallopava (W. B. Cooke) Bhatt and Kendrick1 was originally described as a causal agent of encephalitis in turkey poults2. Because of new outbreaks of encephalitis of turkeys and chickens caused by D. gallopava (H. G. Blalock, W. T. Derieux, L. K. Georg and M. Ranck, personal communications), the widespread occurrence of D. gallopava in natural and man-made heated habitats should be noted.
Foundations of Team Computing: Enabling End Users to Assemble Software for Ubiquitous Computing

Team computing concerns the coordination of teams comprised of software components, devices, and humans operating in ubiquitous computing environments. Teams have no central control: elements play their roles autonomously, and overall behavior is emergent. The proposed model promotes resilience to incompleteness and inconsistency in team designs, as well as to run-time faults. Team computing is geared towards enabling end users to design and deploy their own teams in domains such as home surveillance, assisted living, and energy management. This paper presents the foundations of team computing, including its operational semantics and a framework to automate the verification of desired behaviors. The paper also discusses the implementation of a software infrastructure for the automatic deployment of systems based on team designs.
On the Künneth formula for intersection cohomology

We find the natural perversity functions for which intersection cohomology satisfies the Kunneth formula
Maximum likelihood DOA estimation of multiple wideband sources in the presence of nonuniform sensor noise

We investigate the maximum likelihood (ML) direction-of-arrival (DOA) estimation of multiple wideband sources in the presence of unknown nonuniform sensor noise. New closed-form expression for the direction estimation Cramer-Rao-Bound (CRB) has been derived. The performance of the conventional wideband uniform ML estimator under nonuniform noise has been studied. In order to mitigate the performance degradation caused by the nonuniformity of the noise, a new deterministic wide-band nonuniform ML DOA estimator is derived and two associated processing algorithms are proposed. The first algorithm is based on an iterative procedure which stepwise concentrates the log-likelihood function with respect to the DOAs and the noise nuisance parameters, while the second is a noniterative algorithm that maximizes the derived approximately concentrated log-likelihood function. The performance of the proposed algorithms is tested through extensive computer simulations. Simulation results show the stepwise-concentrated ML algorithm (SC-ML) requires only a few iterations to converge and both the SC-ML and the approximately-concentrated ML algorithm (AC-ML) attain a solution close to the derived CRB at high signal-to-noise ratio.
The impact of economic downturns on marketing

Abstract The Great Recession of 2008–2010 affected the global and U.S. economies and its companies more universally than any economic downturn since the Great Depression. This study explores how the Great Recession influenced the marketing decisions of firms and the resulting long-term effects on marketing within business-to-business companies. Empirical evidence from previous recessions suggests that companies should focus on their customers and increase their marketing efforts during a recession. However, many companies typically slash their marketing budgets during economic downturns. Authors found that during the Great Recession, companies reacted differently than in previous recessions with their marketing responses. Authors conclude their analysis by proposing that the Great Recession will have three long-term effects on marketing in business-to-business companies.
Elastic effects in flow of viscoelastic liquids

Abstract Propagation of information in a viscoelastic liquid can occur through an elastic shear wave mechanism. The comparison of the shear wave velocity with t
The Rotation of the White Light Solar Corona at Height 4 R sun from 1996 to 2010: A Tomographical Study of Large Angle and Spectrometric Coronagraph C2 Observations

Solar rotational tomography is applied to Large Angle and Spectrometric Coronagraph (LASCO) C2/Solar and Heliospheric Observatory (SOHO) observations covering the period 1996-2010, resulting in a set of electron density maps at a height of 4 R ? from which rotation rates can be calculated. Large variation of rotation rates is measured. Rates are dominated by the Carrington rotation rate (14.18?deg?d?1 sidereal), but at times over the solar cycle, rates are measured between ?3 and 3?deg?d?1 relative to the Carrington rotation rate. Rotation rates can vary considerably between latitudes, even between neighboring latitudes. They can remain relatively stable or change smoothly over long periods of times, or can change rather abruptly. There are periods for certain latitudes (for example, the equator at solar maximum) when the movement is dominated by rapid structural reconfiguration, not a coherent rotation. These results raise new questions regarding the link between the Sun and the corona, and provide fresh challenges to interpretations of the coronal structural evolution and the development of large-scale coronal models. In particular, can interchange reconnection provide an explanation of the considerable latitudinal differences in rotation rates, and what mechanism can explain abrupt changes in rotation rates?
Multipole line strengths for linear Hund's case (a) molecules

Abstract Generalized line strength formulae for Hund's case (a) type linear molecules have been derived through the use of spherical tensors and Clebsch-Gordon angular momentum coupling coefficients. Explicit formulae for rotational line strengths, or Honl-London factors, of dipole and quadrupole moments have been tabulated. A general multipole line strength formula for Hund's case (a) type linear molecules has been calculated using the assumptions of isotropy and the Born-Oppenheimer approximation.
Lycopene Accumulation Induced by 2-(4-Chlorophenylthio)-Triethylamine Hydrochloride

After fruits, roots, or the mycelium of certain plants were treated with 2-(4-chlorophenylthio)-triethylamine hydrochloride, lycopene was detected in the tissue. This is the first known success in causing lycopene to accumulate in a wide range of carotenogenic tissues that normally do not accumulate the pigment at some stage of development. The response should be of value in the study of carotenoid biosynthetic pathways and gene control mechanisms.
Naphthalene derivatized TiO2–carbon hybrid materials for efficient photocatalytic splitting of water

Abstract We report a facile approach for the synthesis of TiO2–Carbon (C) hybrid formed by a ligand-to-metal charge transfer (LMCT) complexation between a small organic molecule precursor, 2,3-dihydroxynaphthalene (DN) and TiO2 nanomaterial. The resultant photocatalysts were characterized by powder X-ray diffraction (XRD), surface area and porosity analysis, Raman spectroscopy, diffuse reflectance spectroscopy (DRS), photoluminescence (PL) spectroscopy, transmission electron microscopy (TEM), and by X-ray photoelectron spectroscopy (XPS). Carbonization by N2 pyrolysis at 800 °C altered the physical properties of the TiO2 as evidenced by the increase in the surface area of TiO2 from 6.5 m2 g−1 to 12.5 m2 g−1 and fluorescence quenching of TiO2 emission. The photocatalytic performances of these TiO2–C hybrid materials were evaluated by calculating the amount of hydrogen evolved from the decomposition of water under solar simulated illumination. A marked improvement was observed from ∼0 to 2.6 μ mol/g TiO 2 /h evolved from the bare TiO2-0 and TiO2–C-240 composites, respectively. These results suggested that anchoring of C onto the TiO2 surface can harness effective transfer of electrons through the TiO2–C hetero junction, and promote the photocatalytic performance of TiO2.
The effects of different solar flare characteristics on the global thermosphere

Abstract Given the ability of global models of the upper atmosphere to utilize high-resolution solar spectra to specify the solar soft X-ray and EUV irradiance, researchers now have the ability to perform detailed theoretical analysis of the response of the upper atmosphere to dynamic solar forcing more completely than ever before. Therefore, it is possible to develop a more quantitative understanding of the response of the thermosphere to solar flares. In this study, the effect of different characteristics of solar flares on the thermosphere is investigated. This is done in a theoretical manner, using synthetic solar irradiance data that is based on observations as input to the global ionosphere-thermosphere model (GITM). Specifically, the neutral response to the total incident energy, peak flare magnitude, background irradiance magnitude, duration of the impulsive phase, and decay time is investigated. It is found that the density response at 400 km altitude is linearly dependent on the total integrated energy above the background level being deposited into the atmosphere, and that the day-side response is strongly dependent on both the total incident energy into the system and the peak flare magnitude. Also, the decay time of the flare is important in determining the time at which the maximum global response occurs. Finally, the duration of the impulsive phase is found to have little effect on the global response of the system.
Orbital Origins of Helices and Magic Electron Counts in the Nowotny Chimney Ladders: the 18 – n Rule and a Path to Incommensurability

Valence electron count is one of the key factors influencing the stability and structure of metals and alloys. However, unlike in molecular compounds, the origins of the preferred electron counts of many metallic phases remain largely mysterious. Perhaps the clearest-cut of such electron counting rules is exhibited by the Nowotny chimney ladder (NCL) phases, compounds remarkable for their helical structural motifs in which transition metal (T) helices serve as channels for a second set of helices formed from main group (E) elements. These phases exhibit density of states pseudogaps or band gaps, and thus special stability and useful physical properties, when their valence electron count corresponds to 14 electrons per T atom. In this Article, we illustrate, using DFT-calibrated Huckel calculations and the reversed approximation Molecular Orbital analysis, that the 14-electron rule of the NCLs is, in fact, a specific instance of an 18 - n rule emerging for T-E intermetallics, where n is the number of E-supported T-T bonds per T atom. The structural flexibility of the NCL series arises from the role of the E atoms as supports for these T-T bonds, which simply requires the E atoms to be as uniformly distributed within the T sublattice as possible. This picture offers a strategy for identifying other intermetallic structures that may be amenable to incommensurability between T and E sublattices.
Rare air of motion

Dynamics of the Upper Atmosphere. BySusumo Kato. Pp.233. ISBN 90-277-1132-1. (Reidel: 1980.) Dfl. 57, 29.95.
Human SSRP1 Has Spt16-dependent and -independent Roles in Gene Transcription

The facilitating chromatin transcription (FACT) complex, a heterodimer of SSRP1 and Spt16, has been shown to regulate transcription elongation through a chromatin template in vitro and on specific genes in cells. However, its global role in transcription regulation in human cells remains largely elusive. We conducted spotted microarray analyses using arrays harboring 8308 human genes to assess the gene expression profile after knocking down SSRP1 or Spt16 levels in human non-small cell lung carcinoma (H1299) cells. Although the changes of these transcripts were surprisingly subtle, there were approximately 170 genes whose transcript levels were either reduced or induced >1.5-fold. Approximately 106 genes with >1.2-fold change at the level of transcripts were the common targets of both SSRP1 and Spt16 ( approximately 1.3%). A subset of genes was regulated by SSRP1 independent of Spt16. Further analyses of some of these genes not only verified this observation but also identified the serum-responsive gene, egr1, as a novel target for both SSRP1 and Spt16. We further showed that SSRP1 and Spt16 are important for the progression of elongation RNA pol II on the egr1 gene. These results suggest that SSRP1 has Spt16-dependent and -independent roles in regulating gene transcription in human cells.
Oligonucleotide-directed assembly of materials: Defined oligomers

A nano-architectural system that has high variability while maintaining component specificity is described. Tetraphenylcyclobutadiene(cyclopentadienyl)cobalt complexes and phenyleneethynylene trimers were synthesized and subsequently modified with oligonucleotides utilizing standard phosphoramidite chemistry. The resulting oligonucleotide modified organics (OMOs) were characterized by UV-vis spectroscopy, fluorescence spectroscopy, and phosphate analysis. Hybridization of these OMOs resulted in a series of self-assembled oligomeric hybrids of varying length and topology. These hybrids were characterized by melting temperature, polyacrylamide gel electrophoresis, and fluorescence spectroscopy. This model system demonstrates the power of DNA to self-assemble modules of interest-independent of the module itself.
A reparameterization of the prisoner's dilemma game

A parameterization of the prisoner's dilemma paradigm is constructed based on recent research on the theory of risk and risk preference. The conflict is cast as intrapersonal and in terms of a risk parameter and an inducement to accept the risk, sometimes interpretable as fear and greed respectively, both acting in the context of a level for the game relative to the status quo. These correspond to the independent variables directly under the control of the experimenter. The dependent variable is the strength of the tendency to defect. These variables are acting in the context of an experimental environment which includes the benevolence or hostility of another player which is assumed to contribute to the risk variable only. Some suggestions are made for the controlled study of conjoining a hostile environment.
What About the Baby? The New Cult of Domesticity and Media Images of Pregnancy

This article explores the explosion of images of pregnancy in the media since 9/11. Recent articles from The New York Times to academic journals have noted a marked increase in the representations of traditional gender roles since 2001, what the author here is comparing with the cult of domesticity that arose in the 19th century as an attempt at gaining cultural organization in a time of upheaval. According to Brown (2005), our culture is also facing the death of modernity—the promise of a better future. The author ties these seemingly disparate ideas together by quantitatively and qualitatively analyzing representations of pregnancy in the media. As the author details, the focus on pregnancy may be an attempt to instill faith in a future that has been rendered uncanny and unknowable by the recent awareness of our potential annihilation. The implications and dangers of this form of temporal linking are discussed.
Reduction of Listeria monocytogenes in Raw Catfish Fillets by Essential Oils and Phenolic Constituent Carvacrol

: The antimicrobial activity of various essential oils and carvacrol was determined on fresh raw catfish fillets against a 4-strain Listeria monocytogenes mixture representing serotypes 1/2b, 3b, 4b, and 4c that were predominantly isolated from catfish processing environments. Thyme oil, oregano oil and carvacrol exhibited concentration and time dependent responses in broth against L. monocytogenes; for example 0.5% concentrations resulted in 4 log CFU/mL reduction within 30 min whereas 0.1% concentrations required more than 24 h for the same level of reduction. Lemon, orange, and tangerine oils, at 0.5% showed listeriostatic effect in which 4 log CFU/mL of the initial L. monocytogenes load was unchanged at 4 °C in 10 d whereas 1% concentrations were listericidal in a time dependent manner. Apart from carvacrol, efficacy of tested essential oils in reducing L. monocytogenes and total microbial load from catfish fillet was very limited. Dipping treatment of catfish fillets in 2% carvacrol solution for 30 min at 4 °C reduced L. monocytogenes to an undetectable level from their initial load of 5 log CFU/g and reduced total microbial load from catfish fillets by approximately 5 log CFU/g. In sensory analysis trained panelist preferred control samples over 2% carvacrol treated samples implying potential limitation in applicability of carvacrol for fillet treatments.
The curvature and variability of wrist and arm movements

The control of wrist rotations is critical for normal upper limb function, yet has received little attention. In this study, we characterized path shape of wrist rotations in order to better understand the biomechanical and neural factors governing their control. Subjects performed step-tracking wrist rotations in eight directions “at a comfortable speed” and “as fast as possible.” For comparison, we also analyzed subjects’ arm movement paths in a similar task. We found significant differences between wrist and arm movements. Wrist paths were more curved and more variable than arm paths (p < 0.001). The increased curvature and variability can be explained in part by neuromuscular noise (in actuation and sensing) which is known to increase from proximal to distal in the upper limb. The curvature and variability of wrist paths increased with movement speed (p < 0.001), further implicating (signal-dependent) noise. However, noise cannot explain all of our observations. For example, we found that wrist rotations exhibit a systematic pattern: outbound and inbound paths between the same two targets tend to veer to opposite sides of a straight line. We provide evidence indicating that this type of systematic pattern is not likely caused by noise or other neural causes, but may be explained by the unique biomechanics of the wrist.
Pathogenesis of the hantavirus pulmonary syndrome

Hantavirus pulmonary syndrome caused by hantaviruses in the Americas presents as a broad clinical spectrum ranging from brief febrile prodrome with only thrombocytopenia to rapidly progressive fulminant pulmonary edema and shock. This vascular leak syndrome confined almost exclusively to the lung is initiated by the noncytolytic infection of capillary endothelial cells. A number of pathogenic mechanisms have been proposed, including immune cell-mediated injury, cytokine-mediated injury and enhanced VEGF responses from intercellular junctions resulting from highly specific virus–integrin interactions. This review examines evidence for each of these potential mechanisms, with relevant references to its sister syndrome, hemorrhagic fever with renal syndrome, in Eurasia. Any mechanism or combination of mechanisms must be able to explain the massive pulmonary capillary leak at the severe extreme of the spectrum, a disease manifestation without parallel in clinical medicine.
Thieno[3,4-b]pyrazines: Synthesis, Structure, and Reactivity

A general synthetic route has been developed for the efficient preparation of 2,3-disubstituted thieno[3,4-b]pyrazines. These methods eliminate problems in the preparation of the precursor 3,4-diaminothiophene and utilize α-diones prepared through the reaction of the appropriate organocuprates with oxalyl chloride. This combination allows the convenient preparation of thieno[3,4-b]pyrazine and its 2,3-disubstituted analogues (where substituent = methyl, hexyl, octyl, decyl, dodecyl, and phenyl) in high yield. Characterization of the structure and reactivity of this class of compounds is also described, including the results of structural, electrochemical, and pKa studies.
On the mechanism of conversion of 4-carboxy-3,4-dihydro-3-phenyl-1(2H)-isoquinolones to indeno[1,2-c]isoquinolines by thionyl chloride

Abstract It has been known for a long time that thionyl chloride can effectively mediate the transformation of 4-carboxy-3,4-dihydro-3-phenyl-1(2H)-isoquinolones to indeno[1,2-c]isoquinolines. The mechanism of this unique transformation, however, remains to be established. Evidence is presented to demonstrate that (1) the two-electron dehydrogenation precedes Friedel–Crafts cyclization and (2) the two-electron dehydrogenation occurs via H-4 deprotonation and subsequent O-sulfinylation of the lactam moiety instead of C-sulfinylation of the carbon α to the carboxyl group.
On storing concatenable arrays

Previous studies of extendible array storage mappings (esm's) have envisioned arrays as expanding via a sequence of adjunctions of rows and/or columns. Another mechanism for array expansion is the successive (row-wise or column-wise) concatenation of already stored arrays. This type of expansion is facilitated if the addresses of positions of the resultant composite arrays can be obtained easily and systematically from the addresses of positions of the constituent arrays. A property of esm's, termed translatability , is introduced and is argued intuitively to guarantee easy concatenation of stored arrays. The class of persistent two-dimensional translatable esm's is shown to be a one-parameter family of esm's whose initial member is the familiar diagnonal pairing function. The derived explicit form of these esm's permits one to argue algorithmically that they afford one easy concatenation of stored arrays.
Comparison of the choleretic properties of bile acids.

Abstract The choleretic properties of cholic, chenodeoxycholic, and deoxycholic acid and their taurine and glycine conjugates were compared to their ability to form micelles. It has previously been concluded that deoxycholate has the lowest critical micellar concentration; chenodeoxycholate is slightly higher and cholic is much higher. Conjugation with glycine and taurine has little or no effect on the critical micelle concentration. Since the choleretic properties of bile salts are thought to be directly proportional to their osmotic activities, one might suspect that deoxycholic acid would be the least choleretic, chenodeoxycholic slightly more choleretic and cholic much more choleretic, with little difference between the conjugated and unconjugated forms. However, in the present study, cholic, chenodeoxycholic and taurocholic acid produced similar increases in bile flow (450–700 μl/kg) after an equimolar dose (55 μM/kg). Except for the conjugation of deoxycholic acid with taurine, conjugation of these bile acids with glycine or taurine always decreased the choleretic properties of the bile acids. Therefore, it has been concluded that there is not a good correlation between the in vitro osmotic properties of bile acids and their ability to increase bile flow.
Dielectric study of polymer compatibility: Blends of polystyrene/poly-2-chlorostyrene

Abstract The dielectric constant and loss have been monitored isothermally in the frequency plane in the α relaxation region for a series of amorphous compatible and phase separating polymer blends comprising one polar and one relatively non-polar component. Differential scanning calorimetry has been employed for preliminary assessment of the miscibility of a given pair. The system polystyrene/poly-2-chlorostyrene (PS/PoCS) has been found to exhibit miscibility highly dependent on molecular weight and temperature. High molecular weight blends display wide loss spectra; phase separation above a lower critical solution temperature (LCST) results in the narrowing of the loss curves. Low molecular weight polystyrene yields blends which remain homogeneous up to degradation temperatures and exhibit narrow loss peaks. Comparison between PS/PoCS blends and random copolymers of styrene and 2-chlorostyrene is made.
Pond-Level Risk Factors Associated with Columnaris Disease on Mississippi Commercial Catfish Farms

Abstract A large commercial catfish enterprise encompassing over 500 food fish ponds from five farms covering multiple counties in the Mississippi Delta was included in this analysis of columnaris risk factors. A gram-negative bacterium, Flavobacterium columnare, is the cause of columnaris disease and is considered the second-most prevalent bacterial disease in farm-raised catfish. The objective of this study was to determine if pond-level risk factors reported by farm personnel were associated with columnaris disease mortalities. To identify risk factors affecting susceptibility of farm-raised channel catfish Ictalurus punctatus to columnaris disease, a Catfish Management database was developed. Logistic regression was used to model the relationships between probability of columnaris in ponds and risk factors examined. Generalized linear mixed models incorporating hierarchically structured random effects of ponds and one or more fixed-effects risk factors were fitted. In the screening process, each risk ...
BIO-AJAX: an extensible framework for biological data cleaning

As databases become more pervasive through the biological sciences, various data quality issues regarding data legacy, data uniformity and data duplication arise. Due to the nature of this data, each of these problems is non-trivial. For biological data to be corrected and standardized, new methods and frameworks must be developed. This paper proposes one such framework, called BIO-AJAX, which uses principles from data cleaning to improve data quality in biological information systems, specifically in TreeBASE.
Surfactant Control of Phases in the Synthesis of Mesoporous Silica-Based Materials

The low-temperature formation of liquid-crystal-like arrays made up of molecular complexes formed between molecular inorganic species and amphiphilic organic molecules is a convenient approach for the synthesis of mesostructure materials. This paper examines how the molecular shapes of covalent organosilanes, quaternary ammonium surfactants, and mixed surfactants in various reaction conditions can be used to synthesize silica-based mesophase configurations, MCM-41 (2d hexagonal, p6m), MCM-48 (cubic Ia3d), MCM-50 (lamellar), SBA-1 (cubic Pm3n), SBA-2 (3d hexagonal P63/mmc), and SBA-3 (hexagonal p6m from acidic synthesis media). The structural function of surfactants in mesophase formation can to a first approximation be related to that of classical surfactants in water or other solvents with parallel roles for organic additives. The effective surfactant ion pair packing parameter, g = V/a0l, remains a useful molecular structure-directing index to characterize the geometry of the mesophase products, and pha...
Spatial constraints and group behaviour in globular proteins

A comparative analysis has been attempted on the spatial placement of amino acid residues derived from radial, ellipsoidal and exposure arrangements. The group behaviour of residues and their restraining influence in protein folding have been brought out. A study is also made on the geometry of proteins, the exposure arrangement of residues and the spatial distribution of the physical properties of the residues in globular proteins. It has been shown that the group constraints along with the information on the shape of the globular proteins would be highly useful in assigning the spatial and exposure arrangements of residues in globular proteins.
NMF-KNN: Image Annotation Using Weighted Multi-view Non-negative Matrix Factorization

The real world image databases such as Flickr are characterized by continuous addition of new images. The recent approaches for image annotation, i.e. the problem of assigning tags to images, have two major drawbacks. First, either models are learned using the entire training data, or to handle the issue of dataset imbalance, tag-specific discriminative models are trained. Such models become obsolete and require relearning when new images and tags are added to database. Second, the task of feature-fusion is typically dealt using ad-hoc approaches. In this paper, we present a weighted extension of Multi-view Non-negative Matrix Factorization (NMF) to address the aforementioned drawbacks. The key idea is to learn query-specific generative model on the features of nearest-neighbors and tags using the proposed NMF-KNN approach which imposes consensus constraint on the coefficient matrices across different features. This results in coefficient vectors across features to be consistent and, thus, naturally solves the problem of feature fusion, while the weight matrices introduced in the proposed formulation alleviate the issue of dataset imbalance. Furthermore, our approach, being query-specific, is unaffected by addition of images and tags in a database. We tested our method on two datasets used for evaluation of image annotation and obtained competitive results.
Preparation, crystal structure analysis, and catalytic application of [(S)-BINAP]Ni(COD) and [(S)-BINAP]NiBr2

The efficient preparation of [(S)-BINAP]Ni(COD) (1) and [(S)-BINAP]NiBr2 (2) is reported. X-ray crystal structure analysis of these potential precatalysts provides the first structural insights into the nickel−BINAP system at both the 0 and +2 oxidation states.
Pathological characteristics of good and poor interpersonal problem-solvers among psychiatric outpatients

Contrasted good and poor interpersonal problem-solvers (N = 60), as defined by the Means-Ends-Problem-Solving Procedure (MEPS), on indices of psychopathological characteristics, as measured by the Millon Multiaxial Clinical Inventory (MMCI). The results suggest some support for a relationship between performance on the MEPS and psychological adjustment indices (MMCI); however, they do not offer an unambiguous interpretation. Significant differences were found between poor problem-solvers in contrast to good problem-solvers in the direction of relatively more maladjustment for poor problem-solvers. Significant differences were found between black-white good problem-solvers and also between black-white poor problem-solvers. Race may be an important moderator variable in performance on both the MEPS and the MMCI.
Intramolecular vibrational relaxation from C-H stretch fundamentals

Infrared fluorescence measurements have been used to determine the presence or absence of intramolecular vibrational relaxation (or more precisely state mixing) from an excited C–H stretch in 23 representative molecules varying in size from methane to nonbornene. Included are aliphatic hydrocarbons, aromatic molecules, ethers, and ketones, including cyclic molecules. The rate of resonance fluorescence, calculated relative to a nonrelaxing molecule, was used as the criterion of relaxation. Small rates imply state mixing and hence in the large molecule limit, relaxation. The primary correlation with the presence of mixing is with state density; about ten states per wave number (cm−1) are needed to insure mixing. The spread in threshold densities reflects variations in anharmonicity. For some molecules true relaxed (non C–H stretch) fluorescence is observed. These experiments were done in a molecular beam, using a pulsed optical parametric oscillator for excitation and a circular variable filter for spectral...
Ramsey Functions for Quasi-Progressions

A quasi-progression of diameter n is a finite sequence \(\) for which there exists a positive integer L such that \(\) for \(\). Let \(\) be the least positive integer such that every 2-coloring of \(\) will contain a monochromatic k-term quasi-progression of diameter n. We give a lower bound for \(\) in terms of k and i that holds for all \(\). Upper bounds are obtained for \(\) in all cases for which \(\). In particular, we show that \(\). Exact formulae are found for \(\) and \(\). We include a table of computer-generated values of \(\), and make several conjectures.
Sex-specific neuroendocrine and behavioral phenotypes in hypomorphic Type II Neuregulin 1 rats

Neuregulin 1 (NRG1) is an important growth factor involved in the development and plasticity of the central nervous system. Since its identification as a susceptibility gene for schizophrenia, several transgenic mouse models have been employed to elucidate the role NRG1 may play in the pathogenesis of psychiatric disease. Unfortunately very few studies have included females, despite the fact that some work suggests that the consequences of disrupted NRG1 expression may be sex-specific. Here, we used Nrg1 hypomorphic (Nrg1(Tn)) Fischer rats to demonstrate sex-specific changes in neuroendocrine and behavioral phenotypes as a consequence of reduced Type II NRG1 expression. We have previously shown that male Nrg1(Tn) rats have increased basal corticosterone levels, and fail to habituate to an open field despite normal overall levels of locomotor activity. The current studies show that, in contrast, female Nrg1(Tn) rats exhibit enhanced suppression of corticosterone levels following an acute stress, reduced locomotor activity, and enhanced habituation to novel environments. Furthermore, we also show that female, but not male, Nrg1(Tn) rats have impaired prepulse inhibition. Finally, we provide evidence that sex-specific changes are not likely attributable to major disruptions in the hypothalamic-pituitary-gonadal axis, as measures of pubertal onset, estrous cyclicity, and reproductive capacity were unaltered in female Nrg1(Tn) rats. Our results provide further support for both the involvement of NRG1 in the control of hypothalamic-pituitary-adrenal axis function and the sex-specific nature of this relationship.
The theoretical and empirical structure of general well-being

A comprehensive set of variables that have been supported as contributing to overall health and general well-being were analyzed to determine their simple structure using factor analysis and their relative contribution using Pearson correlation. The contributors to general well-being had been theoretically grouped into: emotions, beliefs, temperaments, behaviors, sittuations, experiences and health. The empirical factor structure was compared with the theoretical structure used to develop the variables. Stability was investigated by comparing results with those of another geographically separated group. All subjects were normally functioning working adults. The results demonstrated the feasibility and potential usefulness of using self-report questionnaires with multivariate procedures to measure components of the global general well-being concept.
Mechanisms of Transdermal Controlled Nitroglycerin Administration (I): Development of a Finite-Dosing Skin Permeation System

AbstractA new finite-dosing cell for in vitro skin permeation studies was recently developed to overcome the deficiencies observed in the commercially available Franz diffusion cell and to accomplish the solution hydrodynamics and temperature control required in studying the rate profiles of skin permeation.Results of comparative studies indicated that the improved diffusion cell, named Keshary-Chien diffusion cell, can achieve and maintain the target body temperature on the skin surface and in the receptor solution, which cannot be accomplished by the Franz diffusion cell. Solution mixing efficiency was substantially improved, so the drug distribution and concentration homogeneity could be achieved in the Keshary-Chien diffusion cell within a duration four times shorter than in the Franz diffusion cell; and a 3-fold reduction in the thickness of the hydrodynamic boundary layer was achieved, so the effect of mass transfer in the hydrodynamic boundary layer on the skin permeation rate profiles was minimized.
Incorporating UTAUT Predictors for Understanding Home Care Patients' and Clinician's Acceptance of Healthcare Telemedicine Equipment

Telemedicine programs within health care are experiencing significant growth as healthcare organizations seek to reduce expenditures and improve efficiency. The high costs of treating chronic diseases, compounded by an aging population, has given focus to creating technology-enabled alternatives to support, enhance, or expand patient services. As investments in telemedicine products and services grow at a rapid pace, user technology acceptance has become a key issue in successful implementation. Drawing from the Unified Theory of Acceptance in Technology (UTAUT), this study investigated the predictors of behavioral intention to use Telehealth equipment by patients, clinicians, and agency personnel at Henry Ford e-Home Health Care. Survey data were provided by 126 participants recruited from an eligible population who were either currently using the Telehealth equipment or were familiar with it. Structural equation modeling was used to study the overall fit of the UTAUT model in predicting behavioral intention. Participant type, self-efficacy, anxiety and attitude were tested as moderators. Implications for increasing adoption of Telehealth technology are discussed.
Rape Myth Acceptance, Sexual Trauma History, and Posttraumatic Stress Disorder

The prediction of false rape-related beliefs (rape myth acceptance [RMA]) was examined using the Illinois Rape Myth Acceptance Scale (Payne, Lonsway, & Fitzgerald, 1999) among a nonclinical sample of 258 male and female college students. Predictor variables included measures of attitudes toward women, gender role identity (GRI), sexual trauma history, and posttraumatic stress disorder (PTSD) symptom severity. Using linear regression and testing interaction effects, negative attitudes toward women significantly predicted greater RMA for individuals without a sexual trauma history. However, neither attitudes toward women nor GRI were significant predictors of RMA for individuals with a sexual trauma history. PTSD did not moderate RMA's relationship with attitudes toward women and GRI. This study has clinical implications for treatment as well as for the development of rape myth-dispelling programs.
The role of transportation in the design and implementation of reverse logistics systems

This paper explores the role of inbound and outbound transportation within the context of a reverse logistics (RL) system. The transportation system is analysed and evaluated in terms of specific subsystems (sub-factors) associated with it. The data was collected from two in-depth case studies from two different industries. The research methodology utilised in this study is exploratory case study approach. The analysis of these case studies resulted in propositions and insights regarding RL practices with respect to a transportation system. The transportation sub-factors, propositions, and a framework for effective design and implementation of RL operations with respect to the transportation system are then presented. In conclusion, the results, managerial implications, and future research results are provided.
‘Cold war’ continuities: US economic and security strategy towards Europe

(1994). ‘Cold war’ continuities: US economic and security strategy towards Europe. Journal of Strategic Studies: Vol. 17, The Future of NATO, pp. 82-104.
Histochemical use of lead tetraacetate. II. alpha-Hydroxycarboxylic acid localization.

Lead tetraacetate, reacting in glacial acetic acid, will attack α-hydroxy acids as well as 1,2-glycols to form leucofuchsin-positive aldehyde radicals in contrast to the more limited glycol oxidation of periodic acid. This property of lead tetraacetate suggested that a comparison of tissue sections prepared by both histochemical methods might offer a means of recognizing the sites of α-hydroxycarboxylic linkage in tissues. Sections from organs of 27 human necropsies were prepared in this manner and examined microscopically for staining variations. These examinations indicated that although the α-hydroxycarboxylic linkage might be attacked by lead tetraacetate, it could not be differentially localized in the face of the principal oxidizing action at the 1,2-glycol linkage.
Long-term impact of prior rituximab therapy and early lymphocyte recovery on auto-SCT outcome for diffuse large B-cell lymphoma.

Early lymphocyte recovery following auto-SCT for non-Hodgkin's lymphoma (NHL) has been reported to be associated with improved outcome. The significance of early lymphocyte recovery following a stem cell transplant in NHL subtype diffuse large B-cell lymphoma (DLBCL) in the rituximab era remains unclear. Patients who underwent an auto-SCT at our institution for DLBCL during the time period 1998-2008 (n=115) were included in the study. Patient characteristics were well-balanced in both rituximab naive and rituximab-exposed groups. Prior rituximab therapy did not affect lymphocyte recovery on day 14 or day 28. Lymphocyte recovery on day 14 and day 28 and prior rituximab had no impact on survival after auto-SCT for DLBCL, despite early benefit. Other factors such as age, stage at presentation, number of salvage regimens, mobilization procedure, conditioning regimen, pre-transplant radiation therapy and pre-transplant disease status had no impact on survival. Our data showed that the survival benefit with early lymphocyte recovery and prior rituximab seen in previous reports may be lost with longer follow-up. Prior rituximab therapy does not appear to influence the lymphocyte count at days 14 and 28 following auto-SCT. Our findings suggest that future trials should consider manipulating the immune system as a post transplant intervention to improve long-term outcome.
Flow Maldistribution in Multichanneled Microdevices With In-Line Manifolds

This paper deals with the analyses of fluid flow distribution in a microfluidic device with in-line manifolds. The analysis was performed using commercially available microfluidic simulation software called CoventorWare™. The number of channels in the microfluidic device considered for this study was kept at ten due to limitations on the number of nodes and computational time. Channels with only square profile were analyzed for flow rates varying between 1 to 60 ml/min. The length of the channels was maintained at 1.5 cm for all simulations. The fluid flow distribution characteristics for different channel widths/depths (200, 100, and 75 μm) were investigated. It was observed that the flow rate decreased from the central channels to the outer channels. The flow per channel was symmetric about the geometric centre of the microdevice. The uniformity in flow was accessed using the root mean square value of flow per channel and it decreased with decrease in channel width/depth for a specific flow rate. The difference in the flow rate through the channels increased with increase in total flow rate. Similarly, the spacing between the channels was varied (300, 200, and 100 μm) for a microdevice with channel width/depth of 100 μm and its corresponding flow characteristics were studied for flow rate ranging between 1 ml/min and 60 ml/min. Finally, the length of each manifold was varied between 2500 μm and 1000 μm for understanding the effect of manifold length on flow distribution. The standard deviation of flow per channel did not show much variation with changes in spacing and manifold length. In addition each design of the manifolds was analyzed on the basis of pressure and flow rate as well as velocity profile in each of the channels.Copyright © 2009 by ASME
Coronary arteriographic findings in cocaine abuse-induced myocardial infarction

A 31-year-old black man was admitted with an acute anterior myocardial infarction 20 minutes after IV cocaine abuse. Cardiac catheterization showed a totally occluded left anterior descending artery. Intracoronary and intravenous streptokinase resulted in thrombolysis: repeat angiography showed a normal anterior descending.
Optimal control application in supersonic aircraft performance

Optimal control theory is used in the analysis of the three-dimensional turning performance of supersonic aircraft to generate real-time online optimal trajectories.
Toward an engineering ethics for the global information era

Because they fall prey to increasing relativism as the diversity of interpretive schemata proliferate in a global context, neither traditional Conceptual Ethics nor Virtue Ethics can provide a workable framework for evaluating the ethical significance of the variety of technological systems and structures being set loose upon the planet by contemporary engineering practice. Grounded in the notion of "objective caring", and tempered by the philosophies of Levinas and Heidegger, Material Ethics is proposed as a discourse appropriate for the global Information Era. Development of a heuristic cost/value metric, in terms of which the ethics of engineered products may be assessed, is suggested.
THE DIALECTIC ROLE OF THE FLICKERS OF FREEDOM

One well-known incompatibilist response to Frankfurt-style counterexamples is the ‘flicker-of-freedom strategy’. The flicker strategy claims that even in a Frankfurt-style counterexample, there are still morally relevant alternative possibilities. In the present paper, I differentiate between two distinct understandings of the flicker strategy, as the failure to differentiate these two versions has led some philosophers to argue at cross-purposes. I also explore the respective dialectic roles that the two versions of the flicker strategy play in the debate between compatibilists and incompatibilists. Building on this discussion, I then suggest a reason why the compatibilism/incompatibilism debate has reached a stalemate.