cssi/SciSciGPT-SciSciNet huggingface dataset:
The amino acid requirements for larval development of the hymenopterous parasitoid Exeristes roborator fabricius (Hymenoptera: Ichneumonidae).

Abstract 1. The amino acid requirements for larval development of E. roborator were determined by amino acid deletion from a holidic diet. The results demonstrated that the parasitoid has an absolute requirement for the 10 amino acids, that is, arginine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine. 2. No statistically significant difference in survival was found between insects reared on the control diet and diets lacking alanine, aspartate, cysteine, glutamate, glycine, hydroxyproline, serine or tyrosine and although there were significant differences in development time these were slight. E. roborator , therefore, has no dietary requirement for these amino acids under the present rearing conditions. 3. E. roborator did not survive on diets containing only the 10 essential amino acids.
PIXE-PIGE analysis of teeth from children with and without cystic fibrosis

Abstract Proton-induced X-ray emission (PIXE) and proton-induced gamma emission (PIGE) were used to analyze Ca, Sr, Fe, Zn, Cu and F, Na, P, Mg respectively in teeth of children with and without cystic fibrosis. The accelerators used were the 3 MeV proton Van de Graaff accelerator at the Brookhaven National Laboratory, NY, USA for the first run and the 8 MV FN-tandem Van de Graaff accelerator at the Nuclear Physics Laboratory, Rutgers University, NJ, USA producing a 4 MeV proton beam for the second and third run. Description of the experimental setup, and the data acquisition system are described in the text. A summary of the results on element concentration as a function of types of teeth and correlation studies are in the text and in F.T. Cua, Ph.D. Thesis, Rutgers Univ. (1989).
UDP as the inhibitor of glycogen synthesis from crustacean eyestalks

Abstract The inhibitor of UDPG-glycogen transglucosylase reported earlier to occur in crustacean eyestalks is shown to be uridine-diphosphate (UDP). UDP is shown to be secreted internally, and to participate in the regulation of carbohydrate metabolism in crustaceans.
ISA Wars: Understanding the Relevance of ISA being RISC or CISC to Performance, Power, and Energy on Modern Architectures

RISC versus CISC wars raged in the 1980s when chip area and processor design complexity were the primary constraints and desktops and servers exclusively dominated the computing landscape. Today, energy and power are the primary design constraints and the computing landscape is significantly different: Growth in tablets and smartphones running ARM (a RISC ISA) is surpassing that of desktops and laptops running x86 (a CISC ISA). Furthermore, the traditionally low-power ARM ISA is entering the high-performance server market, while the traditionally high-performance x86 ISA is entering the mobile low-power device market. Thus, the question of whether ISA plays an intrinsic role in performance or energy efficiency is becoming important again, and we seek to answer this question through a detailed measurement-based study on real hardware running real applications. We analyze measurements on seven platforms spanning three ISAs (MIPS, ARM, and x86) over workloads spanning mobile, desktop, and server computing. Our methodical investigation demonstrates the role of ISA in modern microprocessors’ performance and energy efficiency. We find that ARM, MIPS, and x86 processors are simply engineering design points optimized for different levels of performance, and there is nothing fundamentally more energy efficient in one ISA class or the other. The ISA being RISC or CISC seems irrelevant.
Enzyme‐Linked Immunosorbent Assay Detection of Trichothecenes Produced by the Bioherbicide Myrothecium verrucaria in Cell Cultures, Extracts, and Plant Tissues

A rapid technique for trichothecene detection was needed in screening tests of the potential bioherbicide Myrothecium verrucaria (MV), in order to select strains, mutants, or formulations that were void of or that possessed low amounts of these undesirable mycotoxin compounds. Commercially available enzyme‐linked immunosorbent assay (ELISA) plates for trichothecene detection, possessing cross‐reactivity with several trichothecene mycotoxins (e.g., verrucarin A, and J, roridin A, L‐2, E, and H), were tested for their ability to detect trichothecenes produced by a strain of Myrothecium verrucaria (MV) in cell cultures, in plant tissues (hemp sesbania and kudzu) treated with purified roridin A, or ethyl acetate fractions of MV cultures. Evaluations of ELISA assays showed linear responses for standards of verrucarin A and roridin A over a concentration range of 0.2 to 20 ppb. Ethyl acetate or aqueous extractions were used to obtain samples from MV cultures and plant tissues for testing. Trichothecenes were de...
What happened to pastry

This paper describes how Microsoft Research goes about the process of technology transfer, using the experience of transferring the MS Pastry Distributed Hash Table and its applications as an example.
Can Conformational Change Be Described by Only a Few Normal Modes

We suggest a simple method to assess how many normal modes are needed to map a conformational change. By projecting the conformational change onto a subspace of the normal-mode vectors and using root mean square deviation as a test of accuracy, we find that the first 20 modes only contribute 50% or less of the total conformational change in four test cases (myosin, calmodulin, NtrC, and hemoglobin). In some allosteric systems, like the molecular switch NtrC, the conformational change is localized to a limited number of residues. We find that many more modes are necessary to accurately map this collective displacement. In addition, the normal-mode “spectra” can provide useful information about the details of the conformational change, especially when comparing structures with different bound ligands, in this case, calmodulin. Indeed, this approach presents normal-mode analysis as a useful basis in which to capture the mechanism of conformational change, and shows that the number of normal modes needed to capture the essential collective motions of atoms should be chosen according to the required accuracy.
Registered Dietitians' Use of Multiple Skills

Abstract LEARNING OUTCOME: To determine the need for multiple skills as perceived by members of the American Dietetic Association. One thousand registered dietitians were randomly selected from the American Dietetic Association's membership. Two hundred thirty six (23.6%) completed the 12 page survey. Data provided by the participants were evaluated to determine: 1.) the need for multiple skills, 2.) the impotence and ranking of practice area tasks identified by the Future Search Conference as well as additional possible tasks, 3.) the importance of certification for each task, and 4.) the grouping of skills assessed to be important for securing future dietetic jobs. The skill groups examined were research, education, managing material resources, managing financial resources, managing facilities, marketing services and products, managing human resources, providing programs to the population and providing care to individuals. Using descriptive statistics, registered dietitians overwhelmingly (97.6%) perceived the need for multiple skills. For every Future Search Conference practice area, respondents identified additional tasks and skills needed. Within each practice area an average of 87.0% of the respondents felt there was a need for certification(s). The skill groups were analyzed according to what the respondents felt they would not do, what they are currently doing, and what they logically could do. Results of this study indicate that the skills currently used and those that could logically be used (in rank order) were as follows: education (75.%), research (72,4%), managing human resources (70.7%), marketing services and products (68.6%), provide care to individuals (67.6%), and manage financial resources (53.5%).
Cloning, expression and directed mutagenesis of the genes for ribulose bisphosphate carboxylase/oxygenase.

The dominant natural form of ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is composed of large (L) 55-kDa and small (S) 15-kDa subunits. This enzyme (as the L8S8 form) is widely distributed among oxygenic photosynthetic species and among chemosynthetic bacteria. Another form lacking small subunits is found as an L2 dimer in Rhodospirillum rubrum or an L oligomer of uncertain aggregation state from Rhodopseudomonas sphaeroides. The present article reviews two basically different approaches in cloning the R. rubrum gene for RuBisCO. One results in high level expression of this gene product fused with a limited aminoterminal stretch of β-galactosidase and the other results in expression of wild-type enzyme in Escherichia coli. Also reviewed are a number of reports of cloning and assembly of the L8 S8 enzyme in using E. coli L and S subunit genes from Anacystis nidulans, Anabaena 7120, Chromatium vinosum and Rps. sphaeroides.
Random laser speckle based modulation transfer function measurement of midwave infrared focal plane arrays

Direct measurement of the modulation transfer function (MTF) of focal plane arrays (FPAs) using random laser speckle approaches for the visible/near-infrared wavelength band has been well documented over the last 20 years. These methods have not transitioned to the midwave infrared (MWIR) primarily because other techniques have been sufficient and MWIR laser sources with sufficient output power have been unavailable. However, as the detector pitch decreases, MTF measurements become more difficult due to diffraction, while potential MTF degradation due to lateral carrier diffusion crosstalk makes accurate MTF characterization critical for sensor system design. Here, a random laser speckle FPA MTF measurement approach is adapted for use in the MWIR that utilizes a quantum cascade laser coupled with an integrating sphere to generate the appropriate in-band random speckle. Specific challenges associated with the technique are addressed including the validity of the Fresnel diffraction assumptions describing the propagation of the random speckle field from the integrating sphere to the FPA. Improved methods for estimating the power spectral density (PSD) of the measured speckle that reduce data requirements are presented. The statistics and uniformity of the laser speckle are presented along with PSD measurements and estimated MTFs of a MWIR FPA.
Fabrication of separate adjacent provisional restorations.

W hen adjacent teeth are prepared to receive castgold or porcelain restorations, provisional restoration of these teeth may present a dilemma. A multiunit acrylic resin splint may be convenient to fabricate, but it will be more difficult for the patient to clean. Although nonsplinted restorations are more accessible to interproximal flossing, fabrication of separate adjacent provisional restorations can be tedious. In a conventional technique separate units are formed from a one-piece acrylic resin splint by sectioning through each connector with a disk. It may be necessary to add acrylic resin interproximally, with subsequent finishing and polishing, to reestablish the proximal contact.
Prions: Portable prion domains

Abstract Self-propagating abnormal proteins, prions, have been identified in yeast; asparagine/glutamine-rich ‘prion domains' within these proteins can inactivate the linked functional domains; new prion domains and reporters have been used to make ‘synthetic prions', leading to discoveries of new natural prions.
Ethics in Geriatric Research

As the need for more information on age-related clinical pharmacology grows, there will be an increased emphasis on research involving elderly individuals. Ethical concerns surrounding the protection of elderly research subjects is increasingly a topic of debate. The increased vulnerability of institutionalized elderly, recruitment and retention of elderly subjects, and informed consent are important issues that affect the conduct of research in this population. Investigators should be aware of the special problems associated with research in the older population and be prepared to deal with these before embarking on a research project. This article provides the pharmacy practitioner with an introduction to the basic ethical principles relating to the conduct of research involving the elderly and gives an overview of some of the important problems that may be encountered. Issues such as autonomy, competence, informed consent, proxy, and rights of privacy are outlined. Circumstances in which elderly patien...
Comparing the Mini-BESTest with the Berg Balance Scale to evaluate balance disorders in Parkinson's disease

Objective. The purpose of this study was to explore the usefulness of the Mini-BESTest compared to the Berg Balance Scale in evaluating balance in people with PD of varying severity. We evaluated (1) the distribution of patients scores to look for ceiling effects, (2) concurrent validity with severity of disease, and (3) the sensitivity/specificity of separating people with or without postural response deficits. Subjects. Ninety-seven people with PD were tested for balance deficits using the Berg, Mini-BESTest, Unified Parkinson's Disease Rating Scale (UPDRS) III and the Hoehn & Yahr (H&Y) disease severity classification. Setting. Clinical research facility at Oregon Health & Science University. Results. The Mini-BESTest is highly correlated with the Berg (r = 0.79, P < 0.001), but avoids the ceiling compression effect of the Berg for mild PD (skewness -2.30 Berg, -0.93 Mini-BESTest). Consequently, the Mini-BESTest is more effective than the Berg for predicting UPDRS Motor score (P < 0.001 Mini-BESTest versus P = 0.86 Berg), and for discriminating between those with and without postural response deficits as measured by the H&Y (ROC differential P = 0.06). Conclusion. The Mini-BESTest is a promising tool for discerning balance deficits in patients with PD, most importantly those with more subtle deficits.
The application research of hyperchaos encryption in security communications

Against the nature of hyperchaos dynamic system, a modified hyper-chaotic sequence encryption algorithm was given. This method used the dynamic system of TNC hyperchaos. And proved to have the effective ability of exhaustive attack and anti-nonlinear reorganization; Used Sub-Nyquist sampling interval to increase the key space, this method has the ability of anti-nonlinear reorganization attack; Realized the algorithm's encryption and decryption by using Matlab simulation platform and got some satisfactory results which make out that the arithmetic is faster and easier implementation by software, had a large key space and so on.
Passive transfer of experimental allergic neuritis in Lewis rats by direct injection of sensitized lymphocytes into sciatic nerve.

Lewis rats injected intraneurally with 6×104 to 6×106 lymph node cells from nerve-immunized donors of the same strain showed more intense cellular infiltrates in nerve and more intensive demyelination than did controls given cells from adjuvant-immunized or non-injected control donors. Twenty of twenty-two recipients of cells from nerve-immunized donors showed perivenular round cell infiltrates; only four of thirty-four controls showed comparable infiltrates.
Building Effective Scheduling Algorithms for Sensor Networks

In wireless sensor networks, some sensor nodes can switch to a sleep state to conserve energy if their neighbors can provide similar sensing coverage. In reality, when more sensor nodes sleep, a sensor network's coverage may degrade. In this paper, we evaluate the coverage-aware sleep scheduling algorithm in areas with uneven event distributions and study its performance on event detection rate and event detection delay. There are two major improvements in this paper: first, we add the components of event generator into this paper and collect data on event detection rate and event detection delay. Second, we analyze sleep probability and energy consumption for coverage-aware sleep scheduling algorithm. Compared with randomized deployment strategy, the density adaptive deployment performs better on event detection delay and event detection rate.
A quasiclassical trajectory study of final state distributions in collisions of fast H(D) atoms with HF(DF)

This paper presents a detailed theoretical study of the reactive and nonreactive final vibrational state distributions obtained in collisions of translationally hot H atoms with HF (and isotopic counterparts D+HF, H+DF, and D+DF). The potential surface used is surface No. 5 of Brown, Steckler, Schwenke, Truhlar, and Garrett, and it is characterized by a high barrier (1.9 eV) to F atom transfer. Cross sections and other dynamical information were generated using the quasiclassical trajectory (QCT) method, and we also did classical infinite‐order‐sudden (CIOS) calculations to characterize vibrational excitation mechanisms. Perhaps our most important results refer to the nonreactive final state distributions, where we find that collision of H with the F atom end of HF gives a broad vibrational distribution spread over many states while collision with the H atom end of HF gives a narrow distribution in which v’=1 is the only significant excited product. For D+HF, only the first collision mechanism is importan...
A 126.9–132.4GHz wide-locking low-power frequency-quadrupled phase-locked loop in 130nm SiGe BiCMOS

This paper explores a common-emitter buffer-based frequency multiplier which can be applied to the phase-locked loop (PLL) to boost the overall output frequency and locking range by locking the PLL in a lower fundamental frequency and then multiplying the fundamental frequency to a higher output frequency. An integer PLL with a frequency quadrupler is designed to verify this technique in 130nm SiGe BiCMOS technology. The post-layout simulation shows this D-band (110–170GHz) PLL has a wide locking range from 126.9 to 132.4GHz. The output power into a 50Ω load is −30dBm. The total power consumption is approximately 16.95mW. The PLL phase noise at 1MHz offset frequency is −66dBc/Hz. Its settling time is ∼2µs. The microchip area is 850µm×760µm.
Ingroup Identification and Group-Level Narcissism as Predictors of U.S. Citizens’ Attitudes and Behavior Toward Arab Immigrants

In four studies, the authors explored factors contributing to negative attitudes and behavior toward Arab immigrants in the United States. In Study 1, Americans reported greater threat from Arabs, compared to other groups (e.g., Latino, Asian). In Study 2, they tested the effects of ingroup identification and group-level narcissism on attitudes toward Arab, Latino, Asian, and European immigrants. Identification interacted with group narcissism in predicting attitudes toward Arab (but not other) immigrants, such that identification predicted negative attitudes toward Arab immigrants only at mean and high levels of group narcissism. Study 3 explored the convergent and discriminant validity of the group narcissism construct. In Study 4, the authors added a behavioral dependent measure. Again, ingroup identification predicted negative behavior and attitudes toward an Arab immigrant group (but not comparison groups) only at mean and high levels of group narcissism. Theoretical and practical implications are discussed.
Using existing modeling techniques for manufacturing process reengineering: a case study

The paper presents a case study of a nine-step approach for conducting manufacturing process reengineering. The approach consists of a modeling framework composed of seven tightly integrated conceptual models that are developed from existing modeling techniques. The study was conducted at a major computer manufacturer to solve several organizational and technical problems that were directly related to long product cycle time. Some of the successes of the study include a 75% reduction in cycle time and in work-in-process (WIP).
SUBTHRESHOLD PHOTOIONIZATION SPECTRA OF CH3I PERTURBED BY SF6

Abstract We present pressure- and temperature-dependent subthreshold photoionization spectra of pure CH 3 I (up to 200 mbar) and CH 3 I doped into SF 6 (up to 1 bar). At the high pressures studied, no temperature effect is observed for the subthreshold structure, thus ruling out vibrational autoionization of CH 3 I as an ionization mechanism. Moreover, analysis of photocurrent intensities as a function of CH 3 I number density (pure CH 3 I) and SF 6 number density (CH 3 I doped into SF 6 ) shows a quadratic dependence in the former case and a linear dependence in the latter case. This is discussed in terms of dopant (D)/perturber (P) interactions involving the excited state processes D ∗ +P → D + +P − and D ∗ +P → [DP] + +e − , where D ∗ is a discrete Rydberg state of the dopant (CH 3 I). From the density dependence of the subthreshold structure of CH 3 I/SF 6 , the electron scattering length in SF 6 is determined and compared to a value recently obtained from autoionizing states in the same system.
A search for peas ( Pisum sativum L.) showing strain specificity for symbiotic Rhizobium leguminosarum

A wide variety of primitive pea types and other genetic stocks was tested under gnotobiotic conditions for nodulation and nitrogen fixation with each of two strains of Rhizobium leguminosarum. A strain of Turkish origin (3624) formed active nodules on all 375 pea lines tested, while 24 peas from Afghanistan, 1 from Israel and 1 from Turkey were totally or partially resistant to nodulation by the other strain (2550), which was of European origin. Tests with other Rhizobium strains established that the plasmid pRL5JI present in strain 3624 was required for nodulation of those lines not nodulated by the strain 2550.
Teaching the unteachable: on the compatibility of learning analytics and humane education

This paper is an exploratory effort to find a place for learning analytics in humane education. After distinguishing humane education from training on the basis of the Aristotelian model of intellectual capabilities, and arguing that humane education is distinct by virtue of its interest in cultivating prudence, which is unteachable, an account of three key characteristics of humane education is provided. Appealing to thinkers of the Italian Renaissance, it is argued that ingenium, eloquence, and self-knowledge constitute the what, how, and why of humane education. Lastly, looking to several examples from recent learning analytics literature, it is demonstrated that learning analytics is not only helpful as set of aids for ensuring success in scientific and technical disciplines, but in the humanities as well. In order to function effectively as an aid to humane education, however, learning analytics must be embedded within a context that encourages continuous reflection, responsiveness, and personal responsibility for learning.
Oxidation products of acylated anthocyanins under acidic and neutral conditions

Abstract Acylated anthocyanidin-3,5-diglucosides are oxidized with H 2 O 2 under acidic conditions to acylated ortho -benzoyloxyphenylacetic acid esters. When the same reaction is carried out under neutral conditions, the reaction product is the 3- O -acyl-glucosyl-5- O -glucosyl-7-hydroxy coumarin.
Evaluating Development Interventions in Peace-Precarious Situations

International development assistance tackles sociopolitical and socioeconomic problems, typically with formal host government and population buy-in (or acquiescence), in settings with complex interrelated challenges. A new subset of contemporary interventions, however, faces all of the usual development challenges plus security threats affecting foreign and local staff, host country leadership, and local counterparts necessary for generating sustainable improvements. Threats can arise as a function of individuals’ roles in promoting development. Evaluations of the results of development interventions in peace-precarious situations not only confront the same extra challenges implementation does in these settings, but must also account for the consequences of a panoply of interactive intangibles, shifting dynamically over time. Salient contextual features shaping feasible and useful approaches to evaluation in peace-precarious situations include adherence to management and monitoring and evaluation (ME elasticity in design and resources; and dynamics of stakeholder politics and broader political relationships.
Localization of nucleoside triphosphatase activity to the inner nuclear envelope and associated heterochromatin

Nuclear-envelope nucleoside triphosphatase activity (NTPase), an enzymatic activity thought to participate in RNA transport, was localized in rat liver in situ after brief perfusion with 3% paraformaldehyde. Reaction product was distributed along the nucleoplasmic side of the nuclear envelope (NE) in heterochromatin, was only occasionally found at nuclear pores, and nuclear deposition was selectively blocked by inhibitors of NE NTPase activity. Our results suggest that NTPases, which are active in the NE and which participate in RNA transport, are not specifically associated with nuclear-pore complexes.
Effects of nuclear forces on neutrino opacities in hot nuclear matter

Neutrino opacities are analyzed in terms of correlation functions for density, spin density, isospin density, and spin-isospin density operators. In a long-wavelength limit appropriate to the scattering of thermal neutrinos in most situations relevant to the supernova, the opacities coming from the neutral current interaction are given in terms of susceptibilities, \ensuremath{\partial}${\ensuremath{\rho}}_{i}$/\ensuremath{\partial}${\ensuremath{\mu}}_{j}$, where ${\ensuremath{\rho}}_{i}$ are the various densities and ${\ensuremath{\mu}}_{j}$ the associated chemical potentials. These susceptibilities are calculated in the framework of a Skyrme interaction, one which has been used in calculations of the hot equation of state, supplemented by spin-dependent terms from other sources. There is a large reduction in the Gamow-Teller part of the cross sections in all of the domains of temperature, proton fraction, and density which were studied. Effects of the screened Coulomb force also cause a large reduction in the opacity arising from the Fermi interaction of the neutrino with protons, in some domains of density and temperature.
Quantitative organellar proteomics analysis of rough endoplasmic reticulum from normal and acute pancreatitis rat pancreas

The rough endoplasmic reticulum (RER) is a central organelle for synthesizing and processing digestive enzymes and alteration of ER functions may participate in the pathogenesis of acute pancreatitis (AP). To comprehensively characterize the normal and diseased RER subproteome, this study quantitatively compared the protein compositions of pancreatic RER between normal and AP animals using isobaric tags (iTRAQ) and 2D LC-MALDI-MS/MS. A total of 469 unique proteins were revealed from four independent experiments using two different AP models. These proteins belong to a large number of functional categories including ribosomal proteins, translocon subunits, chaperones, secretory proteins, and glyco- and lipid-processing enzymes. A total of 37 RER proteins (25 unique in arginine-induced, 6 unique in caerulein-induced and 6 common in both models of AP) showed significant changes during AP including translational regulators and digestive enzymes, whereas only mild changes were found in some ER chaperones. The six proteins common to both AP models included a decrease in pancreatic triacylglycerol lipase precursor, Erp27, and prolyl 4-hydroxylase beta polypeptide as well as a dramatic increase in fibrinogen alpha, beta and gamma chains. These results suggest that the early stages of AP involve changes of multiple RER proteins that may affect the synthesis and processing of digestive enzymes.
Clinical sampling device for rapid viral diagnosis by transmission electron microscopy

A clinical sampling device useful for rapid viral diagnosis was constructed from a plastic-shafted throat swab by excision of the cotton or alginate wool tip and heat shaping the end of the plastic shaft to accommodate a Formvar- and carbon-coated grid. The device can be conveniently carried in the coat pocket and can be readily used to obtain specimens at the bedside. Various types of fluids containing virus particles may be examined by transmission electron microscopy to obtain a presumptive diagnosis, often in less than 1 hour.
Outsourcing strategies for apparel manufacture: a case study

Purpose – The redesign of a product supply chain, in terms of production, cost and delivery capabilities can be effectively accomplished by mapping, analyzing and simulating the changes in the supply chain prior to implementation. The case being discussed pertains to the apparel industry in the USA. The beginning of 2005 marked the end of a 30‐year old quota on the apparel market in the USA. This has led many western apparel manufacturers to outsource their production to low‐labor cost countries. This in‐turn has led to increased customer lead‐times. This paper aims to discuss how the implementation of proper IT systems and supply chain measures can reduce lead‐times and also reduce total cost.Design/methodology/approach – An integrated approach is utilized to model the impact of apparel outsourcing added to a US apparel producer supply chain by studying the process map, data analysis, and simulation of the supply chain using Visio, Excel and @Risk simulation software. Using Monte Carlo simulation, the hy...
Mechanistic aspects of group transfer polymerization

The experimental evidence supporting the involvement of enolate anions in group transfer polymerization(GTP) is reviewed. The results of silyl group exchange studies between living silyl ketene acetal-ended oligomers under typical GTP conditions are discussed. It is concluded that the observations of significant amounts of silyl group exchange in the presence of polymerizing monomer are not consistent with the originally proposed “associative mechanism” based on the GTP Criterion which precludes intermolecular silyl group exchange.
Natural language command of an autonomous micro-air vehicle

Natural language is a flexible and intuitive modality for conveying directions and commands to a robot but presents a number of computational challenges. Diverse words and phrases must be mapped into structures that the robot can understand, and elements in those structures must be grounded in an uncertain environment. In this paper we present a micro-air vehicle (MAV) capable of following natural language directions through a previously mapped and labeled environment. We extend our previous work in understanding 2D natural language directions to three dimensions, accommodating new verb modifiers such as go up and go down, and commands such as turn around and face the windows. We demonstrate the robot following directions created by a human for another human, and interactively executing commands in the context of surveillance and search and rescue in confined spaces. In an informal study, 71% of the paths computed from directions given by one user terminated within 10m of the desired destination.
Squamous cell carcinoma of renal pelvis

Abstract Squamous carcinoma of the renal pelvis was diagnosed in only 11 of 2,166 renal tumors (0.5 %) seen over a twenty-seven-year period. The combination of an insidious onset and a prolonged duration of symptoms (median: 5 months) resulted in all patients having invasive disease at diagnosis. Ten patients died two to twenty-eight months after diagnosis (median survival: 5 months), and only 1 patient is currently alive at nine months. We conclude that the treatment of choice is radical nephrectomy followed by adjuvant chemotherapy.
A Surprising Etiology of Neonatal Seizures

Neonatal seizures are the most common neurologic emergency in the newborn period. Given that there is a broad differential diagnosis, emergency evaluation should first focus on identifying treatable causes. The following case describes a neonate who presented to the emergency department with seizures. The seizures were provoked by electrolyte abnormalities secondary to dehydration and renal failure from intestinal obstruction secondary to congenital duodenal atresia. This case illustrates a unique and potentially treatable etiology of neonatal seizures.
Notes on ‘open systems’ in building technology

Abstract Careful reading of the literature, in light of recent developments in theory and practice in building, suggests that systems theory as understood in the field of building technology is ready for updating. These notes support the movement in ‘systems’ discussions toward an explicit recognition of the concept of control—or the action of assembling or transforming elements in the staged assembly of buildings. The notes suggest that technical issues, while critical, are insufficient to explain innovation, failure or other aspects of change in technical systems for building. A more adequate understanding is, it is argued, necessarily linked to questions of control.
Evaluating Self-Report Measures of Narcissistic Entitlement

The present work further delineates the psychometric properties of two self-report measures of entitlement: the Psychological Entitlement Scale (PES) and the Entitlement/Exploitativeness subscale from the Narcissistic Personality Inventory (NPI-EE). Past research shows that these measures diverge in their relations with psychological distress and self-esteem. We draw upon conceptual distinctions between normal and pathological narcissism to explain these differences. We also provide additional reliability information for each measure. Study 1 (n = 436) uses self-report data on exploitive entitlement, non-exploitive entitlement, and the traits of the Five-Factor Model (FFM) to evaluate the nomological nets of the PES and NPI-EE. Study 2 (n = 497) uses self-report data on self-esteem and antisocial behaviors to evaluate the criterion-related validity of the PES and NPI-EE; it also replicates the Study 1 FFM profile results. Study 3 (n = 142) investigates the test-retest reliability of the PES and NPI-EE (along with estimates of their internal consistencies) across a 2-week interval. The PES had strong retest reliability and showed a pattern of correlates characteristic of grandiosity (e.g., higher levels of antagonism [immodesty in particular]); the PES also had a strong positive association with non-exploitive entitlement and a modest positive association with self-esteem. The NPI-EE captured some features consistent with vulnerability (e.g., links with higher Neuroticism [anger in particular] and somewhat lower self-esteem) and also had adequate retest reliability in light of its internal consistency. Implications for the assessment of narcissistic entitlement are discussed.
Effect of cordycepin on CRF stimulation and steroid inhibition of ACTH secretion by rat pituitary cells

Abstract Isolated pituitary cells prepared from adrenalectomized rats secrete ACTH in response to CRF, and this response is inhibited by corticosterone. Both the stimulation of release by CRF and the inhibition of release by corticosterone are antagonized by cordycepin (3'-deoxyadenosine). Inhibition of CRF-stimulated secretion by cordycepin is apparently not related to inhibition of RNA synthesis, since high doses of actinomycin D do not affect ACTH secretion. More likely, cordycepin's inhibition of secretion stems from its inhibition of adenylate cyclase activity. Inhibition of corticosterone action by cordycepin is qualitatively similar to that previously reported for actinomycin D. This effect of both drugs is probably due to inhibition of RNA synthesis. Significantly, a low dose of cordycepin has a greater inhibitory effect on cortico-sterone action than on total cellular RNA synthesis. Cordycepin is reported to preferentially inhibit messenger RNA synthesis, and a low dose preferentially inhibits appearance of cytoplasmic RNA in pituitary cells. These data suggest that corticosterone-induced RNA is a cytoplasmic (messenger) RNA.
Treatment of Infrapopliteal Critical Limb Ischemia in 2013: The Wound Perfusion Approach

The primary goals of treatment for critical limb ischemia (CLI) are alleviation of ischemic rest pain, healing of arterial insufficiency ulcers, and improving quality of life. These goals are directed toward preventing limb loss and CLI-related mortality. Arterial revascularization serves as the foundation of a contemporary approach to promote amputation-free survival. Mounting evidence supports a wound-directed angiosome revascularization approach, increasingly achieved with endovascular techniques. Innovations in technology and wound-perfusion strategy have advanced patient care and are accelerating the pace of CLI treatment. The evolving angiosome revascularization approach has been augmented with a multidisciplinary wound care strategy that deserves particular emphasis. These state-of-the-art advances in CLI management are reported herein with considerations for the future treatment of CLI.
Accelerated sampling of the free gas resonance elastic scattering kernel

In this work, we present the derivation and investigation of a new Doppler broadening rejection sampling approach for the exact treatment of resonance elastic scattering in Monte Carlo neutron transport codes. Implemented in OpenMC, this method correctly accounts for the energy dependence of cross sections when treating the thermal motion of target nuclei in elastic scattering events. The method is verified against both stochastic and deterministic reference results in the literature for 238U resonance scattering. Upscatter percentages and mean scattered energies calculated with the method are shown to agree well with the reference scattering kernel results. Additionally, pin cell and full core keff results calculated with this implementation of the exact resonance scattering kernel are shown to be in close agreement with those in the literature. The attractiveness of the method stems from its improvement upon a computationally expensive rejection sampling procedure employed by an earlier stochastic resonance scattering treatment. With no loss in accuracy, the accelerated sampling algorithm is shown to reduce overall runtime by 3–5% relative to the Doppler broadening rejection correction method for both pin cell and full core benchmark problems. This translates to a 30–40% reduction in runtime overhead.
Pain and emotion: a biopsychosocial review of recent research.

Pain is the most common symptom reported to health care providers, is a driving force of health care utilization and lost productivity, and exacts a substantial toll on the afflicted, their loved ones, and society in general. Pain is a prevalent symptom not only in primary medical care and specialty pain clinics, but also in mental health and substance dependence treatment settings. Thus, it is vital that psychologists remain abreast of recent theory and research that informs and directs case conceptualization, assessment, and intervention among patients experiencing pain.
Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons

Levels of the proinflammatory cytokine tumor necrosis factor alpha (TNFalpha) are increased in postmortem brain and cerebral spinal fluid from patients with Parkinson's disease (PD). This observation provides a basis for associating TNFalpha with neurodegeneration, but a specific toxicity in dopamine (DA) neurons has not been firmly established. Therefore, we investigated TNFalpha-induced toxicity in DA neurons by utilizing primary cultures of embryonic rat mesencephalon. Exposure to TNFalpha resulted in a dose-dependent decrease in DA neurons as evidenced by decreased numbers of tyrosine hydroxylase-immunoreactive (THir) cells. TNFalpha toxicity was selective for DA neurons in that neither glial cell counts nor the total number of neurons was decreased and no general cytotoxicity was evidenced by lactate dehydrogenase assay. Many of the cells which remained immunoreactive for TH had shrunken and rounded cell bodies with broken, blunted, or absent processes. However, TNFalpha-treated cultures also contained some THir cells which appeared to be undamaged and possibly resistant to TNFalpha-induced toxicity. Additionally, immunocytochemistry revealed basal expression of TNFalpha receptor 1 (p55, R1) and TNFalpha receptor 2 (p75, R2) on all cells within the mesencephalic cultures to some degree, even though only DA neurons were affected by TNFalpha treatment. These data strongly suggest that TNFalpha mediates cell death in a sensitive population of DA neurons and support the potential involvement of proinflammatory cytokines in the degeneration of DA neurons in PD.
Cost model analysis of DFT based fault tolerant SOC designs

A lot of emphasis has been placed on the test cost of chips and a variety of models have been proposed in the literature. However they do not include the fault tolerance consideration. Existing models are incomplete by the fact that most do not take into account the costs involved once the chip reaches the market. This paper addresses these limitations by introducing the cost model for a fault tolerant system taking into account the reliability factor of a system. This model can help designers analyze the need for a fault tolerant system and its feasibility in the industry. This paper models the costs involved during the life cycle of a chip. Two case studies using the proposed model are presented in order to substantiate the need to put fault tolerant designs into chips.
Generating DNA profiles from immunochromatographic cards using LCN methodology

The aim of this research was to obtain DNA profiles from immunochromatographic test devices which have already yielded positive results with body fluids obtained from fourteen volunteers. Three different immunochromatographic cards for the identification of human blood and one for the identification of human saliva were used for this research. Each body fluid was detected using the appropriate immunochromatographic card. The used cards were kept at room temperature for various lengths of time. The membranes were removed at the end of the designated times and the entire strip was extracted using low copy number (LCN) extraction procedure. The extracted DNA was amplified using reduced amplification volume and higher PCR cycle numbers. Autosomal STR profiles were detected using AmpFlSTR(®) Identifiler™ PCR Amplification Kit from Applied Biosystems (AB). Additionally, DNA extracted from the male volunteers was amplified using the AB AmpFlSTR(®) Yfiler™ PCR Amplification Kit. Analysis of the amplified products was carried out by capillary electrophoresis injection on the AB 3130xl Genetic Analyzer. The generated DNA data was analyzed using the SoftGenetics GeneMarker(®) HID Version 1.7 software. Autosomal and Y-STR DNA profiles were obtained from most of the cards which were stored at room temperature for up to three months. DNA profile was obtained from all four types of the immunochromatographic cards used in this study. These profiles were concordant with the profiles obtained from the donors' reference samples.
Evaluation of the Fracture Strength for Silicon Carbide Layers in the Tri‐Isotropic‐Coated Fuel Particle

A program to develop new methods to measure the fracture strength of the chemical vapor deposition SiC coatings in nuclear fuel particles has been carried out. Internal pressurization and crush test techniques were developed and applied to prototype-sized tubular and hemispherical shell specimens. The fracture strength measured from each test method applying the Weibull two-parameter distribution, and Weibull parameters were measured. It was shown that data generated with each test technique were independent of the test technique applied. This implies that the developed test methods are reliable and provide reasonable strength data. For the same material, fracture strength varied with the specimen geometry and loading configuration. These size and loading configuration effects on the fracture strength are explained with the concept of effective surface.
Stoichiometric and kinetic studies of phenolic antioxidants from Andean purple corn and red-fleshed sweetpotato.

Stoichiometric and kinetic values of phenolics against DPPH (2,2-diphenyl-1-picrylhydrazyl) were determined for Andean purple corn (Zea mays L.) and red sweetpotato (Ipomoea batatas). Both crops had higher antioxidant capacity and antiradical kinetics than blueberries and higher or similar anthocyanin and phenolic contents. The second-order rate constant (k2) was 1.56, 1.12, 0.57, and 0.26 (mg antiradical/mL)-1 s-1 for red sweetpotato, Trolox, purple corn, and blueberry, respectively. On the molar basis of active hydroxyl groups, k2‘ showed the same order as for k2. Corn cob and sweetpotato endodermis contributed the most in phenolic compounds and antioxidant capacity. Both crops studied can be considered as excellent novel sources of natural antioxidants for the functional food and dietary supplement markets. Keywords: Antioxidant activity; DPPH stoichiometry and kinetics; phenolics; purple corn; red sweetpotato
Identification of gene expression elements in Histomonas meleagridis using splinkerette PCR, a variation of ligated adaptor PCR.

abstract: Histomonas meleagridis is the causative agent of blackhead disease in gallinaceous birds. Limited genetic information exists for this organism, with the majority of sequence information coming from the coding regions of genes. No information is available for intergenic regions that contain DNA elements required for the regulation of gene expression. In this study, we demonstrate that splinkerette PCR, a variation of ligated adaptor PCR, can be used to identify regions of unknown sequence that lie upstream and downstream of known genomic sequences. Using this technique, we identified upstream sequences of 2 β-tubulin genes. Sequence analysis identified the 5′ coding portions of the β-tubulin genes, the intergenic regions, and 2 different open reading frames encoding for a putative serine/threonine phosphatase and a putative ras-related protein, racG. We predict that these intergenic regions contain polyadenylation and cleavage signals for the 2 open reading frames and initiator elements for the ...
Research on the Dependency among the Non-functional Properties of Web Services

This paper analyzes the features of non-functional properties of Web Services, studies their classification, advance a method to dispose the uncertain features with fuzzy sets and grey systems, provide a measurement (i.e. relevance degree, based on rough sets) of dependency among the non-functional properties, which evolves a description (i.e. support degree, based on rough sets too) of essentiality how the decision factors affect the decision results, and supply a new approach of QoS evaluation.
Feasibility and utility of positive psychology exercises for suicidal inpatients

article i nfo Objective: The objective was to assess the feasibility and acceptability of nine positive psychology exercises delivered to patients hospitalized for suicidal thoughts or behaviors, and to secondarily explore the relative impact of the exercises. Method: Participants admitted to a psychiatric unit for suicidal ideation or behavior completed daily positive psychology exercises while hospitalized. Likert-scale ratings of efficacy (optimism, hopelessness, perceived utility) and ease of completion were consolidated and compared across exercises using mixed models accounting for age, missing data and exercise order. Overall effects of exercise on efficacy and ease were also examined using mixed models. Results: Fifty-two (85.3%) of 61 participants completed at least one exercise, and 189/213 (88.7%) assigned exercises were completed. There were overall effects of exercise on efficacy (χ 2