cssi/SciSciGPT-SciSciNet huggingface dataset:
Step, swim, and scratch motor patterns in the turtle.

The turtle generates a variety of coordinated hindlimb movements, including different forms of locomotion and scratching. The intact turtle produces forward step, forward swim, and backpaddle. Following spinal cord transection, rostral, pocket, and caudal scratches can be evoked by mechanical stimulation of the shell. Comparisons of the kinematics and motor patterns of these six behaviors provide insights regarding neuronal mechanisms underlying their production. All six behaviors were characterized by alternating hip flexion and extension and by an event during which force was exerted against a substrate. The portion of the cycle occupied by hip flexion or extension movement varied across behaviors. Hip extension occupied well over half the cycle period in the forward step and the caudal scratch. The cycle was split into approximately half hip flexion and half hip extension for the forward swim, the backpaddle, and the rostral scratch. Hip flexion occupied over half the cycle in the pocket scratch. The swim and scratch forms had curvilinear, crescent-shaped toe trajectories and a single burst of monoarticular knee extensor activity during each cycle. The forward step had a linear toe trajectory and two bursts of knee extensor activity during each cycle, one during swing and one during stance. Timing of monoarticular knee extensor onset was similar for: the forward swim, the rostral scratch, and the swing phase burst of forward step; the pocket scratch and the stance phase burst of forward step; and the backpaddle and the caudal scratch. Amplitudes of muscle activity varied among the six behaviors; high amplitudes of activity were associated with events during which force was exerted against a substrate. These times of force exertion were: stance phase in the forward step, powerstroke in the forward swim and the backpaddle, and rubs of the limb against the shell in the scratch forms. The six behaviors studied represent a range of parameter values, as evidenced by relative durations of hip flexion to hip extension, knee extensor phasing, and electromyogram (EMG) amplitudes. This range of behaviors could be produced by assembling different combinations of neurons from a common pool, with all six behaviors likely sharing some basic circuitry. The extent of shared circuitry may be greater between behaviors with similar timing, e.g., backpaddle and caudal scratch.
Degrees and Hamiltoneity

Obviously any pancyclic graph must contain a Hamilton cycle. In this chapter we look at some results relating the Hamiltonian property to the set of degrees of vertices in the graph.
The Language of Nature

On account of his political lectures and speeches at the open-air meetings of the London Corresponding Society in the 1790s, Thelwall was widely regarded as one of the most powerful public speakers of the age. Wordsworth thought that he had ‘extraordinary talent’ and Coleridge regarded him as ‘the voice of tens of thousands’.2 William Hazlitt described him more ambiguously as ‘[t]he most dashing orator I ever heard’, ‘the model of a flashy, powerful demagogue — a madman blessed with a fit audience’ and ‘a volcano vomiting out lava’? In James Gillray’s iconic depiction of a mass meeting of reformers at Copenhagen Fields in the fall of 1795, Thelwall towers over the crowd from a podium in the foreground, fist pumping the air, lips parted mid-sentence — a posture that recalls his invitation to audiences for his weekly lectures in the Strand to ‘take my lungs for a pair of bellows to blow an alchymist’s fire withal’.4 (Figure 5.1) Thelwall prided himself on such spontaneous overflows of powerful feeling. Rather than compose lectures in tranquillity he spoke from notes and outlines, asserting that ‘the clothing and embellishments ought to be left to the time of delivery: for that language will always be most emphatic, which the warmth of the moment supplies’.5
Deflowering the voting virgin: Piety, political advertising, and the pleasure prerogative

ABSTRACTIn this essay, the author examines political advertisements that employ the tropology of sex and romance in order to promote voter participation. The ads appear initially to be humorous attempts at “perspective by incongruity,” disrupting U.S. political culture by seeking to activate otherwise disengaged young women as a formidable political constituency. Although the ads challenge standards of political propriety, they leave intact the pieties of postfeminism and patriarchy which govern political dialogue on both the left and the right. Furthermore, the ads foster a “pleasure prerogative” which conflates female political agency with romantic engagement, (hetero)sexual consummation, and consumer consciousness. By valorizing the instant gratification of fleeting contact with the ballot box over the subdued satisfaction of a long-term commitment to deliberative democracy, these ads ultimately are corrosive to democratic culture.
Device integration for ESD robustness of high voltage power MOSFETs

The ESD robustness of a power MOSFET device is addressed in this paper. It is shown that by a novel device integration of the power output transistor with SCR, the ESD performance can be improved from less than 2 kV to greater than 6 kV. This is accomplished with no impact on the transistor performance or its application in circuit design. >
Pulmonary Hypertension Patient Navigation: Avoiding the Perfect Storm

Pulmonary arterial hypertension (PAH) is a progressive, incurable disease that presents a challenging journey for all involved. Specialized, complex care and treatment is needed for this population of patients, and should be provided in an organized, systematic manner to promote optimal patient outcomes. The concept of patient navigation can be used as a framework for the pulmonary hypertension (PH) center, so that care delivery is well structured and PAH patients have a guide to assist them through all aspects of the health care continuum. This article will focus on how a PH patient navigation program can be implemented and the role of a PH nurse navigator, using the Christiana Care Health System Pulmonary Hypertension Program in Newark, Delaware, as an example. There have been many advances in PAH diagnosis and treatment in the last 20 years, and the time has come to introduce a PH patient navigation model that can be used as a guide to structure PH programs.
Nonfamilial Juvenile Polyposis Syndrome with Exon 5 Novel Mutation in SMAD 4 Gene

Juvenile polyposis syndrome (JPS) is a rare autosomal dominant hereditary disorder, characterized by multiple juvenile polyps in the gastrointestinal tract and an increased risk of colorectal cancer. JPS is most frequently caused by mutations in the SMAD4 or BMPR1A genes. Herein, we report a child with juvenile polyposis syndrome (JPS) with a novel mutation in the SMAD4 gene. An 8-year-old boy presented with recurrent rectal bleeding and was found to have multiple polyps in the entire colon. The histology of the resected polyps was consistent with juvenile polyps. Subsequent genetic screening revealed a novel mutation in SMAD4, exon 5 (p.Ser144Stop). To the best of our knowledge, this mutation has not been reported before. Offering genotypic diagnosis for patients with JPS is an important step for strategic plan of management.
Chapter 4: Institutional Investors

A large body of behavioral finance literature focuses on the behavioral biases of individual investors in their trading choices. The research shows that sophistication is related to the level at which these behavioral biases influence investors’ trading choices. This chapter reviews the literature on institutional investors’ trading behavior and finds that, consistent with the level of investor sophistication, institutional investors are less subject to the common behavioral biases. However, some behavioral biases are also present in institutional trading, and more so among less sophisticated practitioners. Evidence also shows that institutional investors engage in some trading choices such as herding, momentum trading, and under-diversification, which could be symptoms of behavioral biases. Based on the reviewed research, these trading behaviors are not value reducing. Overall, evidence indicates that institutional investors are less subject to behavioral biases, making markets more efficient.
Cultural Revolution and Zhou Enlai

Chapter 4 examines how the Cultural Revolution disrupted Zhou’s efforts to rebuild Sino-Japanese relations and also how he tried to save his colleagues and proteges from this brutal ideological liquidation campaign. The newly published official biographies and chronologies of Zhou Enlai and other latest primary sources on Chinese leaders tell compelling stories.
Experimental test bed to de-risk the navy advanced development model

This paper presents a reduced scale demonstration test-bed at the University of Texas' Center for Electromechanics (UT-CEM) which is well equipped to support the development and assessment of the anticipated Navy Advanced Development Model (ADM). The subscale ADM test bed builds on collaborative power management experiments conducted as part of the Swampworks Program under the US/UK Project Arrangement as well as non-military applications. The system includes the required variety of sources, loads, and controllers as well as an Opal-RT digital simulator. The test bed architecture is described and the range of investigations that can be carried out on it is highlighted; results of preliminary system simulations and some initial tests are also provided. Subscale ADM experiments conducted on the UT-CEM microgrid can be an important step in the realization of a full-voltage, full-power ADM three-zone demonstrator, providing a test-bed for components, subsystems, controls, and the overall performance of the Medium Voltage Direct Current (MVDC) ship architecture.
A life-cycle model for wave-dominated tidal inlets along passive margin coasts of North America

Abstract A regional overview of 107 wave-dominated tidal inlets along the U.S. Atlantic coast, U.S. Gulf of Mexico coast, and Canadian Gulf of St. Lawrence coast yielded a generalized wave-dominated tidal inlet life-cycle model that recognized the rotational nature of tidal inlets. Tidal inlets are influenced by concurrently acting processes transpiring over two timescales: short-term, event-driven processes and long-term, evolutionary processes. Wave-dominated tidal inlets are classified into three rotational categories based on net longshore sediment transport direction and rotation direction along the landward (back-barrier) portion of the inlet channel: downdrift channel rotation, updrift channel rotation, or little-to-no channel rotation. Lateral shifting of the flood-tidal delta depocenter in response to available estuarine accommodation space appears to control inlet channel rotation. Flood-tidal delta deposits fill accommodation space locally within the estuary (i.e., creating bathymetric highs), causing the tidal-inlet channel to rotate. External influences, such as fluvial discharge, pre-existing back-barrier channels, and impeding salt marsh will also influence inlet-channel rotation. Storm events may rejuvenate the tidal inlet by scouring sediment within the flood-tidal delta, increasing local accommodation space. Wave-dominated tidal inlets are generally unstable and tend to open, concurrently migrate laterally and rotate, infill, and close. Channel rotation is a primary reason for wave-dominated tidal inlet closure. During rotation, the inlet channel lengthens and hydraulic efficiency decreases, thus causing tidal prism to decrease. Tidal prism, estuarine accommodation space, and sediment supply to the flood-tidal delta are the primary variables responsible for tidal inlet rotation. Stability of wave-dominated tidal inlets is further explained by: stability (S) = tidal prism (Ω) + estuarine accommodation space (V) – volume of annual sediment supply (Mt). Rotating wave-dominated tidal inlets follow a six-stage evolutionary model; whereas wave-dominated tidal inlets that exhibit little-to-no rotation follow a five-stage evolutionary model.
Incitement on Trial: Prosecuting International Speech Crimes: Chapter 1

International and national armed conflicts are usually preceded by a media campaign in which public figures foment ethnic, national, racial or religious hatred, inciting listeners to acts of violence. Incitement on Trial evaluates the efforts of international criminal tribunals to hold such inciters criminally responsible. This is an unsettled area of international criminal law, and prosecutors have often struggled to demonstrate a causal connection between speech acts and subsequent crimes. This book identifies 'revenge speech' as the type of rhetoric with the greatest effects on empathy and tolerance for violence. Wilson argues that inciting speech should be handled under the preventative doctrine of inchoate crimes, but that once international crimes have been committed, then ordering and complicity are the most appropriate forms of criminal liability. Based in extensive original research, this book proposes an evidence-based risk assessment model for monitoring political speech.
Feedback-based projected-gradient method for real-time optimization of aggregations of energy resources

This paper develops an online optimization method to maximize operational objectives of distribution-level distributed energy resources (DERs), while adjusting the aggregate power generated (or consumed) in response to services requested by grid operators. The design of the online algorithm is based on a projected-gradient method, suitably modified to accommodate appropriate measurements from the distribution network and the DERs. By virtue of this approach, the resultant algorithm can cope with inaccuracies in the representation of the AC power flows, it avoids pervasive metering to gather the state of noncontrollable resources, and it naturally lends itself to a distributed implementation. Optimality claims are established in terms of tracking of the solution of a well-posed time-varying convex optimization problem.
The Unexpected Amazon: Past, Present, and Imagined

This essay reviews the following works: Upriver: The Turbulent Life and Times of an Amazonian People. By Michael F. Brown. Cambridge, MA: Harvard University Press, 2014. Pp. vii + 321. $29.95 cloth. ISBN: 9780674368071. In Search of the Amazon: Brazil, the United States, and the Nature of Region. By Seth Garfield. Durham, NC: Duke University Press, 2013. Pp. ix + 343. $26.96 paper. ISBN: 9780822355854. Rainforest Cowboys: The Rise of Ranching and Cattle Culture in Western Amazonia. By Jeffrey Hoelle. Austin: University of Texas Press, 2015. Pp. viii + 196. $45.00 cloth. ISBN: 9780292761346. Tracks in the Amazon: The Day-to-Day Life of the Workers on the Madeira-Mamore Railroad. By Gary Neeleman and Rose Neeleman. Salt Lake City: University of Utah Press, 2014. Pp. ix + 195. $29.95 paper. ISBN: 9781607812753. Amazonian Routes: Indigenous Mobility and Colonial Communities in Northern Brazil. By Heather F. Roller. Stanford: Stanford University Press, 2014. Pp. ix + 342. $70.00 cloth. ISBN: 9780804787086.
Climate shifts and coastal changes in a geological perspective. A contribution to integrated coastal zone management

This Special Issue deals with the impact of climate change on western European coastal systems. Notwithstanding the inherent problems of studying geological data in terms of climate shifts, the results show that on the meso- and the macroscale of time, climatic forcing is a major drive for coastal change. However, its impact is largely influenced by other factors. Sediment availability plays a dominant role in the evolution of coastal systems and it can be considered one of the most important thresholds at the land-ocean interface. Sea-level changes are expected to have a significant impact on most European coasts. There is particular concern for the tidally influenced flats and marshes, and for those coastal areas known to have already a net sediment deficit and to be threatened by erosion. Areas where isostatic uplift has countered sea-level rise until now, are expected to become subject to coastal erosion in the near future under an accelerated sea-level rise scenario. The sensitivity and vulnerability of coastal systems to climate shifts is shown to be largely controlled by storm magnitude and fetch. A particular case of vulnerability is the impact of tsunamis. Finally, the consequences of human interference have been demonstrated in many cases. The implementation of geoscientific studies for rational, comprehensive and cost-effective strategies on a regional or national level of integrated coastal zone management is reviewed.
Drosophila as a Model for Starvation: Evolution, Physiology, and Genetics

Fruit flies of the genus Drosophila have become an important model for energy storage and metabolism at multiple levels of organization. Drosophila species differ substantially in their abilities to survive without food, and many species exhibit latitudinal clines in energy storage and starvation resistance. Variation in starvation resistance can also be generated using experimental evolution, by subjecting populations to starvation selection. Physiological analyses of starvation-selected flies reveal that the entire life history of the animal is affected, particularly larval traits associated with growth and energy storage. As adults, these animals contain large lipid stores, but at the cost of reduced fecundity. The genetic toolkit available for Drosophila melanogaster has also allowed researchers to identify the molecular basis for how energy is stored and distributed to tissues that need it. Insulin signaling and other pathways can be manipulated in tissue- and temporal-specific ways that are revealing fundamental energy regulatory mechanisms common to all animals.
The use of Membranes and Sorbents for Blood Detoxification: Cuprophan Sorbent Membranes

The use of membranes and sorbents for blood detoxification are well published topics in the field of artificial organs. The advantage of the membrane process is that it exhibits low trauma in contact with blood, no particulate is generated, and the removal of large molecular weight substances or cells can be prevented from passage due to the porosity or permeability of the membrane’s wall. Herein lies also a disadvantage in that transport is a function of solute size and discriminate solute removal patterns are thus not possible. The advantage of sorbents is that their physical and chemical characteristics can be matched with those of the solute to be removed. Thereby, specific solute removal patterns different than that of membrane separations and not really as dependent as molecular size can be achieved. Disadvantages in the use of sorbents, however, have been the blood trauma related to damage of blood components or the removal of the cellular elements and particular generation with carryover into the vascular system. As a practical consideration in the use of sorbents for blood detoxification in the treatment of most disease states in which the range of solutes to be removed is broad and generally no one sorbent is totally effective, multiple sorbents must be employed. Past studies have concentrated primarily on the use of a single sorbent.
PERSONAL MONITORING | Passive

Acute or chronic exposure to the thousands of minor components that can be present in the air we breathe may cause adverse health effects. Such exposure may occur in the workplace, home, or outdoor environment. Monitoring of these components is required to ensure compliance with recommended or regulated air quality standards. The preferred monitoring method would give a continuous and accurate measurement of instantaneous changes in the concentration of each harmful species present, in a manner that would model human exposure. The compromise most often applied in practice is to extract the components from a large volume (to provide sensitivity) of breathing zone air together with subsequent laboratory analysis (to provide selectivity).
Four Needles in a Haystack: A Systematic Review Assessing Quality of Health Care in Specialty Practice by Practice Type.

Specialists, who represent 60% of physicians in the United States, are consolidating into large group practices, but the degree to which group practice type facilitates the delivery of high quality...
Abstract NS2: Electronic Stroke Outcome Reporting to Enhance Practice Improvement and Education Among Emergency Nurses, A Pilot Study

Background: Feedback is an effective mechanism to change provider behavior. However, emergency department (ED) nurses who transfer acute stroke patients, rarely receive patient outcomes. Interviews...
OFF State Conduction in Filamentary RRAM

In spite of extensive research, the physics of electric transport in the OFF (high resistance) state of resistive random access memory remains poorly understood. Here, we propose a theory that explains the observed activation nature of that transport, its exponential non-ohmicity, variations between nominally identical structures, and failure trends. Our theory proceeds from the finding that the diffusion transport mechanisms must be ruled out as leading to nonphysically high temperatures ( $T\sim 4000-5000$ K) well above melting. The Schottky emission remains acceptable due to its underlying ballistic transport by ~1 eV electrons spreading the Joule heat over much larger distances without melting. Taking into account, the random fields of charged defects the Schottky emission enables one to describe the device variability and failures.
U.S. Clean Carbon Costs: An Investigation of Georgia Markets and Solar Technology [Kennesaw State University]

This paper investigates how geographical variations affect energy costs throughout the United States by using a Levelized Cost of Energy (LCOE) model. The objective was to deconstruct a nationwide LCOE model and investigate the assumptions that are made on a state level; in this case, Georgia was the chosen sample to exhibit how challenges in solar technology affect the cost of clean carbon energy.
School absence in the United States: understanding the role of STEM-related vocational education and training in encouraging attendance

Recent federal education policies and initiatives in the United States have emphasised the importance of college and career readiness and showing up in school. The Carl D. Perkins Career and Techni...
Re-designing Fashion Design Curricula for a New Generation of Learners

As Gen Z and Millennials are transitioning into higher education and the workforce, a gap between what teachers are teaching today and the unknown needed skills of the future is widening (Weidmer, 2015). The fashion industry is experiencing a revolution not only by rapidly evolving technology, but from consumer demands for more sustainable and responsible practices. As fashion design is inherently hands-on and practice-driven, how do we balance traditional making skills while integrating rapidly expanding technologies? What is considered fundamental fashion design knowledge? Are we ready to instruct this new generation of learners with consideration to their motivations, attitudes and values, while also enhancing our own technological competencies in the process? The purpose of this paper is to share the pedagogical research approach that faculty employed between 2015-2017 to assess the Fashion Design Program at the University of Cincinnati, identify problems, forecast curricular directions, and to begin to translate these findings into actionable outcomes. The paper describes activities and key outcomes with the aim to contribute to the broader conversation around holistic pedagogical strategies for fashion design curriculum development.
Conversion from paper to electronic acute care chemotherapy orders.

PURPOSE UNC Medical Center converted to an electronic health record (EHR) in 2014. This conversion allowed for the transition of paper chemotherapy orders to be managed electronically. This article describes the process for converting inpatient paper chemotherapy orders into the new EHR in a safe and effective manner. SUMMARY A collaborative interdisciplinary approach to the EHR transition enabled our organization to move from using paper chemotherapy orders to fully electronic chemotherapy treatment plans in both ambulatory and acute care areas. Active chemotherapy orders for acute care inpatients were reviewed and transcribed by two oncology pharmacists in the cancer hospital prior to being signed by an attending physician. The newly input orders were independently verified by two pharmacists in the cancer hospital inpatient pharmacy. Nurse review of the signed and verified treatment plans, along with reconciliation of the medication administration record ensured a safe transition to the new EHR workflow. Providers benefit from the ability to review treatment plans remotely, track changes, and include supportive medications in one consolidated location. The coordinated team effort allowed for a smooth transition with minimal interruptions to patient care. CONCLUSION The pharmacist-led, multidisciplinary conversion to electronic chemotherapy orders was safe, accurate, and occurred ahead of schedule for the EHR go-live. Advance communication and planning around scheduled inpatient admissions helped to minimize the impact of the transition from paper to electronic treatment plans. Both pharmacist and physician engagement were necessary to ensure a smooth transition for active inpatient treatment plans.
Robust Hybrid III-V/Si 3 N 4 Laser with kHz-Linewidth and GHz-Pulling Range

We demonstrate a hybrid III-V/Si 3 N 4 laser system robust to coupling losses and reflection variations. We show self-injection locking of a conventional laser diode to a high-Q resonator obtaining 1 kHz linewidth and 2 GHz pulling range.
Moral grandstanding and political polarization: A multi-study consideration

Abstract The present work posits that social motives, particularly status seeking in the form of moral grandstanding, are likely at least partially to blame for elevated levels of affective polarization and ideological extremism in the U.S. In Study 1, results from both undergraduates (N = 981; Mean age = 19.4; SD = 2.1; 69.7% women) and a cross-section of U.S. adults matched to 2010 census norms (N = 1,063; Mean age = 48.20, SD = 16.38; 49.8% women) indicated that prestige-motived grandstanding was consistently and robustly related to more extreme ideological views on a variety of issues. In Study 2, results from a weighted, nationally-representative cross-section of U.S. adults (N = 2,519; Mean age = 47.5, SD = 17.8; 51.4% women) found that prestige motivated grandstanding was reliably related to both ideological extremism and affective polarization.
On learning to thrive in the academy by turning outsiderness into strength

If you don’t see things the same way as everyone else, if you feel like a square peg trying to fit into a round hole, can you succeed in the academy while staying true to yourself? Can you survive, thrive, and make a significant contribution? These personal questions connect with my professional work in multicultural education and ethnic studies, both of which interrogate institutionalized processes and structures in education that benefit groups with power at the expense of everyone else. I have spent much of my professional life trying to figure out how to transform those processes and practices to support the intellects, cultures, identities, and perspectives of students in our schools, and particularly those from communities minoritized on the basis of race. At the same time, I have had to wrestle with various dimensions of my own outsiderness, and learn how to thrive in academe without losing myself. When advising young scholars and graduate students faced with vexing choices that affect their professional and personal lives, I always tell them to listen to their gut, to follow their heart. This is something I learned to do gradually, as I waded through years of distrusting myself. I also advise them that following your heart is not necessarily easy. Academe may well not be organized to support your passions and perspectives, so to thrive, you must be willing to invest effort in learning how academe functions in order to map out a path that fits you. But ultimately, thriving in the academy begins by valuing what makes you, you.
Corporate Personality, Purpose, and Liability

Questions about corporate personality and purpose ramify differently depending on context. For example, the question whether or not, and in what sense, a corporation is, or may be, a “person” will be understood and answered differently if framed as a question of metaphysics, morality, social perception, politics, or law. The same is true of the question whether, and if so, what purposes are attributable to corporations. Recognizing the value of disentangling legal from parallel but non-legal constructs, in this chapter I examine how and why the law personifies groups, and how it modulates the attribution of actions – and liability for same – to corporate persons partly on the basis of corporate purpose. The primary aim is to clarify how corporate purpose mediates the individuation and attribution of actions, and liability for same, to corporations. A secondary aim is to show that legal conceptions of corporate personality and purpose are primordial relative to moral and social conceptions, insofar as reliance on law enables the self-constitution and -presentation of groups.
Hypertension: A new safety risk for patients treated with erenumab.

Objective To identify and analyze postmarketing case reports of elevated blood pressure (BP) associated with erenumab use. Methods A retrospective analysis of postmarketing (spontaneous) case reports of erenumab-associated elevated BP submitted to the FDA Adverse Event Reporting System from May 17, 2018 through April 30, 2020. A case of elevated BP was defined as (a) an initiation of a pharmacological intervention or emergency department visit or hospitalization for emergent de novo or worsening of preexisting hypertension, or (b) BP measurement of ≥140 mm Hg systolic or ≥90 mm Hg diastolic with or without baseline BP measurement reported. Reports of elevated BP associated with erenumab use were analyzed for baseline and demographic information, latency, drug-event causal association, and clinical outcome. Results Sixty-one cases of elevated BP were identified, 86% (49/57) were women and the median age was 56 [range 24-88] years. Forty-one cases were associated with a serious outcome per regulatory criteria, including seven that specified hospitalization. No case reported an outcome of death. The median systolic BP increase was 39 (interquartile range (IQR) 32, 59) mm Hg and median diastolic BP increase was 28 (IQR 18, 41) mm Hg. A total of 27/61 (44%) cases reported treatment for elevated BP (i.e., pharmacologic intervention or emergency department visit/hospitalization). Elevated BP occurred most frequently (28/61, 46%) within a week of the first dose of erenumab. Nineteen cases (19/61, 31%) reported a history of preexisting hypertension. Conclusions This case series suggest an association between elevated BP and use of erenumab. In light of our findings, the erenumab (Aimovig) prescribing information was amended to include hypertension in the Warnings and Precautions section.
Samya: A Geo-Distributed Data System for High Contention Aggregate Data

Geo-distributed databases are the state of the art tools for managing cloud-based data. But maintaining hot records in geo-distributed databases such as Google’s Spanner can be expensive, as it synchronizes each update across a majority of replicas. Frequent synchronization poses an obstacle to achieve high throughput for contentious updateheavy workloads. While such synchronizations are inevitable for complex data types, simple data types such as aggregate data can benefit from reduced synchronizations. To this end, we propose an alternate data management system, Samya, to manage aggregate cloud resource usage data. Samya disaggregates available resources and stores fractions of these resources across geo-distributed sites. Dis-aggregation allows sites to serve client requests independently without synchronization for each update. Samya incorporates a learning mechanism to predict future resource demands. If the predicted demand is not satisfied locally, a synchronization protocol, Avantan, is executed to redistribute available resources in the system. Avantan is a novel fault-tolerant consensus protocol where sites agree on the global availability of resources prior to redistribution. Experiments conducted on Google Cloud Platform highlight that dis-aggregating data and reducing synchronizations allows Samya to commit 16x to 18x more transactions than state of the art cloud geo-distributed systems such as Spanner and CockroachDB.
Robotic, totally endoscopic excision of mitral valve papillary fibroelastoma.

Papillary fibroelastoma is a rare, benign tumor that affects males more frequently than females and that tends to be diagnosed during the fifth or sixth decade of life. It tends to arise on cardiac valves, with the aortic valve being the most frequent location followed by the mitral valve, the tricuspid valve, and the pulmonary valve. We present the case of a robotic-assisted, totally endoscopic excision of a mitral valve papillary fibroelastoma.
"WHAT WOMEN CAN STUDY IN VALPARAÍSO" BY GLADYS PEAKE: ANALYSIS OF A PERIOD SPEECH DOCUMENT

This paper analyzes a document entitled “What women can study in Valparaiso”, written in 1945 (approximately) by one of the first nurses in Chile, Gladys Peake. This document is examined through a discourse analysis, as a document which depicts a particular age, which tells us about the nursing social context, its characteristics and visions at a certain period of time. Results show the prevalence of an own discourse referring the professional nursing origins as a method to obtain social awareness. It argue in favor of its assessment and the necessity of nursing in that period. From there we hope to reflect on the profession in the current context.
Impact Response of Laminated and Sandwich Composites

With increasing use of composites in transportation, military ground and air vehicles, ship structures, infrastructure, sporting goods and the power industry, the understanding of impact and dynamic behavior is critical to composite designers and end-users. A wealth of knowledge has been published on dynamic impact response of composite materials and structures. Yet, with continually emerging materials and processes, there is a lack of systematic structure-property-performance relationships that provide guidelines on dynamic impact behavior of composites.
An emic approach to organizational citizenship behavior of Mexican professionals

Purpose – The purpose of this paper is to examine the dimensionality of emic (culturally specific) organizational citizenship behavior (OCB) of Mexican professionals. Design/methodology/approach – This study considered the collectivistic cultural background of Mexican professional employees and developed a framework based on the emic (culturally specific) dimensions of OCB. Findings – Based on exploratory and confirmatory factor analyses, the authors find that the emic OCB of Mexican professionals is characterized by five dimensions: collegial harmony, organizational camaraderie, professional development, organizational faithfulness, and protecting company resources. Originality/value – The findings also offer incremental contributions to OCB research. In order to correctly capture the entire phenomena of OCB in different cultures, researchers often focus on the emic (specific/cultural unique) approach. Along this vein, the authors identified the Mexican OCB dimensions in an emic approach.
Embedding Group Algebras into Finite von Neumann Regular Rings

Let G be a group and let K be a field of characteristic zero. We shall prove that KG can be embedded into a von Neumann unit-regular ring. In the course of the proof, we shall obtain a result relevant to the Atiyah conjecture.
Aromatic and Volatile Acid Intermediates Observed during Anaerobic Metabolism of Lignin-Derived Oligomers.

Anaerobic enrichment cultures acclimated for 2 years to use a 14C-labeled, lignin-derived substrate with a molecular weight of 600 as a sole source of carbon were characterized by capillary and packed column gas chromatography. After acclimation, several of the active methanogenic consortia were inhibited with 2-bromoethanesulfonic acid, which suppressed methane formation and enhanced accumulation of a series of metabolic intermediates. Volatile fatty acids levels in 2-bromoethanesulfonic acid-amended cultures were 10 times greater than those in the uninhibited, methane-forming consortia with acetate as the predominant component. Furthermore, in the 2-bromoethanesulfonic acid-amended consortia, almost half of the original substrate carbon was metabolized to 10 monoaromatic compounds, with the most appreciable quantities accumulated as cinnamic, benzoic, caffeic, vanillic, and ferulic acids. 2-Bromoethanesulfonic acid seemed to effectively block CH4 formation in the anaerobic food chain, resulting in the observed buildup of volatile fatty acids and monoaromatic intermediates. Neither fatty acids nor aromatic compounds were detected in the oligolignol substrate before its metabolism, suggesting that these anaerobic consortia have the ability to mediate the cleavage of the β-aryl-ether bond, the most common intermonomeric linkage in lignin, with the subsequent release of the observed constituent aromatic monomers.
Assessing psychiatric illness in geriatric patients

Assessing psychiatric illness in geriatric patients can be difficult for a variety of reasons. First, medical comorbidity may obscure the diagnosis. For example, the patient with multiple chronic illnesses will often have many "vegetative" symptoms of either dementia or depression (e.g., fatigue, loss of energy, poor appetite) attributed to the primary medical condition rather than to an underlying psychiatric illness. Second, the phenomenology of psychiatric illness in the elderly is often different. For example, depression in the elderly is often characterized by prominent anhedonia--loss of interest in virtually everything--and physical complaints leading to an unnecessary medical workup. Third, physicians are often reluctant to diagnose new-onset mental illness in their elderly patients. The fear of stigmatizing the patient or physician discomfort with "psychologic language" often results in underdetection of straightforward psychiatric syndromes. This article will focus primarily on detection of 3 of the most common psychiatric syndromes: dementia, depression, and delirium. The field of geriatric psychiatry has done a good job of characterizing the prevalence (Table I) and clinical features of these syndromes. The problem--briefly addressed here--is how to incorporate some of these findings into a busy clinical practice where there is very little time for the assessment of psychiatric symptoms.
Changing Interests of Women: Myth or Reality?

Depuis quelques 50 ans, les psychologues utilisent le “Strong Vocational Interest Blank” (SVIB) pour mesurer les motivations professionnelles; la longue histoire du SVIB et le recent collationnement d'un grand nombre d‘echantillons de professionnels interroges avec des versions anterieures du SVIB, ont rendu possible l'analyse des donnees recueillies sur de longues periodes de temps, determinant l'impact de l'Histoire sur la societe et par voie de consequence sur les motivations professionnelles. Les resultats de six professions autant feminines que masculines “en general”, furent utilisees pour etudier deux points: le premier, l'identification du changement general des motivations professionnelles dans la societe, le second, l'augmentation ou la diminution des differences entre les motivations des femmes et des hommes depuis 50 ans. Les resultats illustrerent la tenacite et la stabilite des motivations des femmes et des hommes “en general” autant que des individus oceupant des professions particulieres, comme ils montrerent egalement d'une facon claire l’elasticite des differences sexuelles dans les aptitudes aux changements. Over 50 years ago, psychologists began using the Strong Vocational Interest Blank (SVIB) to measure occupational interests; the lengthy history of the SVIB and the recent collection of a large number of occupational samples that were represented on earlier versions of the SVIB have made it possible to analyse interest data collected over long time spans to determine the impact of history on society and, consequently, on vocational interests. Data for six occupations, as well as for Women- and Men-in-General, were used to explore two areas; first, general changes in the occupational interests of society were identified, and second, differences between female and male interests were examined to determine if the differences had increased or decreased over the last 50 years. Results from the data illustrated the tenacious stability of occupational interests for Women- and Men-in-General as well as for people in specific occupations. Also, the data graphically illustrated the resilience of sex differences in interests to change.
Far infrared spectroscopy of mineral particles

Mineralogical characterization and far-infrared spectroscopy of laboratory analogues in the wavelength range 57 - 210 mum is performed for interpreting data from Herschelpsilas Photodetector Array Camera and Spectrometer (PACS).
Evaluation of Three Sorghums as Potential Alternative Forages for Crawfish Culture

Three cultivars of Sorghum bicolor (L.) Moench (grain sorghum, forage sorghum, and a sorghum sudangrass hybrid) were evaluated as planted forages for crawfish (Procambarus spp.) in two simulated culture systems, double cropping and crawfish monoculture. Based upon ease of culture, biomass production, and biomass degradation characteristics, grain sorghum and sorghum sudangrass exhibited great potential for either system. With the added advantage of grain production, grain sorghum represents the more attractive option and may provide farmers with a viable alternative to rice for double cropping with crawfish. The sorghum sudangrass produced large amounts of vegetative biomass and also represents a worthwhile forage option for the crawfish fanner. Either of these plants is conveniently incorporated into existing farm operations and could provide options as producers strive to integrate crawfish aquaculture with conventional agriculture.
Use of stable carbon isotope compositions of pyrolytically derived methane as maturity indices for carbonaceous materials

Abstract Nineteen coals of varying ranks and twelve organic-solvent-extracted shales of different ages and maturities were subjected to a long-term, closed system, isothermal (500°C) pyrolysis procedure until no additional methane or carbon oxide gases were generated. Three significant trends were observed: 1. (1) For all of the samples, the stable carbon isotope difference between the total accumulated methane and parent carbon was linearly correlated with yield of methane with r = 0.88. 2. (2) For a series of thirteen model compounds, two lipid-free shales and twelve coals, the H C ratio of each was linearly correlated with the yield of methane with r = 0.93. 3. (3) For a series of eleven coals samples, the O C ratio of each was linearly correlated with the yield of carbon oxides with r = 0.97. The experimental relationships described above indicate that a simple pyrolysis procedure and measurements of the amounts of generated CH4, CO2 and CO relative to the carbon content of the sample and the stable isotopic compositions of the methane and parent organic carbon give 1. (a) an index of the maturity and 2. (b) values which are directly related to the H C and O C ratios of the carbonaceous materials.
An Educator's Guide to the Development of Advanced Practice Competencies in Clinical Social Work.

The 2008 Educational Policy and Accreditation Standards identified 10 core competencies that all social work graduates should master. MSW programs found themselves with a need to identify knowledge, values, and skill statements that reflected what concentration-year students were expected to know and be able to do. In 2009 a group of educators convened at the Council on Social Work Education in Alexandria, VA to develop a model of advanced practice in clinical social work. This article describes the work group's process; identifies and describes the resulting advanced clinical knowledge, values, and skills statements; discusses the key debates and issues that arose during the development of the statements; and concludes with the implications for social work education and practice.
Pharmacodynamics of acute intranasal administration of verapamil: Comparison with IV and oral administration

The present study was conducted in order to examine the intranasal administration of verapamil and compare this route to oral and intravenous administration in a 3 way crossover protocol in five dogs. Unanesthetized, adult mongrel dogs were given verapamil intravenously (0.5 mg/kg), orally (2.5 mg/kg) and intranasally (0.75 mg/kg) with at least a 3-4 day washout period between each administration. Blood samples were collected over a 10 hour period and analyzed for verapamil using HPLC with fluorescence detection. A lead II ECG was monitored to determine the effects of verapamil on heart rate and P-R interval. Following intravenous administration, verapamil was distributed according to a two compartment model. Bioavailability (corrected for dose and elimination rate constant) following intranasal administration (36% +/- 7%) was approximately 3 fold that after oral administration (13% +/- 3%). Absorption from the nasal cavity appeared instantaneous compared to an absorption half-life of 50 +/- 6 min after oral administration. All three routes of administration resulted in significant increases in heart rate and increases in the P-R interval. Maximal P-R interval prolongation occurred after peak plasma concentrations of verapamil. The results of this study suggest that the intranasal route is a viable alternative route of administration for verapamil.
Mixed-Media Filter System for Removal of Multiple Contaminants from Urban Storm Water: Large-Scale Laboratory Testing

AbstractUrban storm water runoff consists of unacceptable levels of nutrients and heavy metals, and a mixed-media filter system is proposed to treat such storm water with multiple contaminants. In this study, a two-dimensional filter simulation test apparatus was constructed to examine the effectiveness of mixed media for the removal of multiple contaminants from synthetic storm water. The mixed media, selected based on several series of batch and column experiments in previous studies, consisted of a mixture of calcite, zeolite, sand, and iron filings. The mixed media was tested for removal of coexisting nitrate, phosphate, Ni, Cu, Cd, Cr, Pb, and Zn at concentrations and conditions relevant for typical urban storm water. Results show that the mixed-media filter was able to maintain high flow rates without any clogging issues, with an average hydraulic conductivity around 30 cm/min. No significant initial release or final desorption of the contaminants was observed. The filter system proved effective fo...
Rheumatic manifestations of endocrine diseases.

Purpose of reviewMusculoskeletal complaints accompanying or as a result of endocrine disorders are common and have been well described. This review re-examines these associations in light of newer information on biology and genetics.Recent findingsIn this article, we describe the recent studies on p