cssi/SciSciGPT-SciSciNet huggingface dataset:
TABLET-BASED TECHNOLOGY INTERVENTION TO IMPROVE OUTCOMES IN HOSPITALIZED OLDER ADULTS

The purpose of this study was to examine the effect of an avatar virtual service animal on cognition, loneliness, depression, delirium, falls and restraint use in hospitalized older adults. The virtual pet speaks to the client, displays a full range of emotions and responds directly to client questions and touch. The study was conducted in a metropolitan teaching hospital. Participants on the intervention unit received the tablet based avatar virtual service animal for their entire hospital stay. Participants on the control unit received a daily visit from a nursing student. Measures (MOCA, 3 Item UCLA loneliness scale, GDS, and CAM) were administered upon study enrollment and prior to discharge. A total of 200 older adults hospitalized on two medical surgical units were enrolled, 100 who received the intervention and 100 controls. All patients were over the age of 65 (mean 80, range 65–96), English speaking, and admitted for a medical diagnosis. There was no significant difference in MOCA scores for participants on the intervention and control units at both study enrollment and study completion. On the intervention unit, there was a statistically significant difference in loneliness scores (p<0.001), and depression scores (p<0.001). There were no significant changes for all measures on the control unit. Fall rates, and hours of restraint use were statistically significantly lower on the intervention unit (p<0.001). There were too few incidences of delirium on both units to allow for statistical modeling. Study findings support the use of this innovative technology for hospitalized older adults.
151 SCREENING PRACTICES FOR DIABETIC NEPHROPATHY BASED ON CLINICAL SETTING.

Purpose To perform a cross-sectional study to determine differences in screening, identification, and management of chronic kidney disease in diabetic patients based on clinical setting. Methods We studied 307 patients with diabetes. These patients were randomly selected from four different clinics, which included two community health centers, an academic endocrine clinic, and an academic primary care clinic. These patients were originally selected for continued quality improvement purposes for the REACH 2010 project in 2005. Annual urine microalbumin and annual serum creatinine were used to determine screening practices. Urine microalbumin > 17 mg/g (men) or > 25 mg/g (women) or GFR Results One community health center had a nonsignificant higher proportion of annual urine microalbumins (p Conclusion These findings suggest that community health centers screen patients at higher proportions but are less likely to identify patients who have a positive test.
A Preliminary Report on the Relationship Between Microaggressions Against Black People and Racism Among White College Students

Previous efforts to understand microaggressions have surveyed stigmatized group members’ experiences of receiving microaggressions. This report presents the first attempt to measure self-reported likelihood of delivering microaggressions rather than receiving microaggressions and to explore the association between the likelihood of delivering microaggressions and racial prejudice. We conducted a cross-sectional survey of 33 black and 118 non-Hispanic white undergraduate students at a large public Southern/Midwest university. Black students reported the degree to which a series of statements would be experienced as microaggressive. White students reported their likelihood of delivering those statements and completed measures of racial prejudice. White students’ self-reported likelihood of engaging in microaggressive acts was significantly related to all measures of racial prejudice. The single item “A lot of minorities are too sensitive” was the strongest predictor of negative feelings toward black people. Results offer preliminary support that the delivery of microaggressions by white students is not simply innocuous behavior and may be indicative of broad, complex, and negative racial attitudes and explicit underlying hostility and negative feelings toward black students.
The Role and Responsibility of Peer Review

This is the last editorial in the series addressing evolving models of peer review. Throughout the year, we have explored different ways in which peer review manifests—in journal articles, in research data, and in professional practice. It has generated conversations about peer review and its relevance in current scholarship and practice, both positive and critical. There have been conversations and comments about the “flaws of traditional peer review.” I hope that these are opportunities for dialogue and growth within the peer review process. Some of the concerns may be around the “traditional” models possibly perceived as driven by commercial publishers and anathema to open access. Or perhaps it is the opinion that peer review perpetuates an elitist framework around “quality.” Or it may be that the process is not transparent enough and thus, provokes skepticism. Each is a valid perspective. Hopefully, though, the conversation does not stop there.
Nanoscience and Water: Public Engagement at and Below the Surface

Publisher Summary Potable water is a threatened resource for the developing world. As nanoscience contributes to the development of nanotechnologies with the potential to provide safe and inexpensive drinking water to developing countries, it is imperative that the public accepts and maintains the technology. Converting the public in developing countries into advocates can increase the probability of overall acceptance of exotic treatment technologies. Anchoring public sentiment positively will improve the options when resolving problems that predictably arise as new water technologies are implemented. Public engagement demands an approach both appropriate to the public as well as to the technology. A municipally based system will demand a different engagement approach than a point-of-use system. As such, a relevant case-specific strategy of engagement must be developed to coincide with the introduction of new water treatment technologies.
Acculturative stress and coping among Korean immigrant elders residing in non-Korean ethnic enclaves:

Few studies that have been conducted on Korean immigrant elders have been carried out in areas without Korean ethnic enclaves due to their small numbers and proportion. This nonprobability cross-sectional study utilized a structured survey to examine the relationships of acculturative stress, coping, and depressive symptoms among 108 non-institutionalized Korean immigrant elders residing in areas without Korean ethnic enclaves. Multivariate analysis results indicated that acculturative stress might be the most significant risk factor for depressive symptoms, which could decrease coping efficacy of social support and increase somatic symptoms of Korean immigrant elders residing in non-Korean ethnic enclaves. Implications for future research, practice, and policy are discussed.
Outcomes of Endovascular Treatments for In-Stent Restenosis in Patients With Mesenteric Atherosclerotic Disease

Abstract Objective Mesenteric angioplasty and stenting (MAS) has surpassed open revascularization as the treatment of choice for mesenteric ischemia. Despite the lower perioperative mortality associated with MAS, the need for reintervention is not infrequent. The purpose of this study was to review the outcomes of patients treated for mesenteric artery in-stent restenosis (MAISR). Methods Clinical data from a single center between 2004 and 2017 were retrospectively analyzed. Standard statistical analysis including Kaplan-Meier estimate for time-dependent outcomes, χ2 test for categorical variables, and two-sample t-test for continuous variables was performed. Primary end points included stent patency and reintervention rate. Secondary end points included mortality and morbidity. Results During the study period, 91 patients underwent primary MAS. In total, 113 mesenteric vessels were treated with 20 covered stents and 93 bare-metal stents. Overall primary patency was 69% at 2 years. At 2 years, primary patency was 83% for covered stents compared with 65% for bare-metal stents (P = .17). Of these 91 primary MAS patients, 27 (30%) were treated for MAISR (32 vessels). Two covered stent patients developed significant restenosis (11%) compared with 25 (34%) bare-metal stent patients (P = .02). The mean age of patients requiring reintervention was 69 years (36% male), with the majority having a history of tobacco use (85%), hypertension (75%), and hyperlipidemia (78%). Fourteen reintervention patients (52%) presented with recurrent symptoms, 10 (37%) had asymptomatic restenosis, and 3 (11%) developed intestinal ischemia. Twelve patients (44%) underwent reintervention with balloon angioplasty alone and 15 (56%) underwent repeated stent placement. Of the 15 patients who had repeated stent placement, 7 patients had covered stents placed. The 30-day mortality rate after reintervention for mesenteric stent restenosis was 0%. Postoperative complications occurred in 15% of patients (myocardial infarction, 4%; reversible kidney injury, 4%; and bowel ischemia requiring surgical exploration, 7%). There was no difference in the perioperative morbidity in comparing symptomatic and asymptomatic patients undergoing reintervention. Mean follow-up after mesenteric reintervention was 31 months, with one-third of patients (n = 9) requiring another reintervention because of either recurrence of symptoms or asymptomatic high-grade restenosis. Assisted primary patency at 2 years was 92% after reintervention with balloon angioplasty and 87% for repeated stent placement, with no statistically significant difference between the groups (P = .66). Conclusions Treatment of MAISR is associated with low mortality and acceptable morbidity. The initial use of covered stents may reduce the need for reintervention.
Poster Abstract: Characterizing Computational Workloads in UAV Applications

Unmanned aerial vehicles (UAV) enable novel but demanding computational workloads that exceed processing capacity of their onboard resources. Mobile and edge devices can support demanding workloads, but they increase network communication and power usage. These resource constraints block potentially transformative UAV applications that execute too slowly or use too much power. This poster presents early efforts to characterize computational demands of emerging UAV applications. We are building a selfie-drone benchmark. Our benchmark will capture processing metrics, e.g., CPU usage, cache misses, power usage, etc. It will also enable characterization across a wide range of local and edge setups. Our benchmark uses a micro services design, making it easy to move workload execution across multiple contexts. Early results show that our benchmark functions well, i.e., accurately detects faces and safely uses flight controls. Further, edge devices matter. A smart phone uses 4X less power than a laptop when executing our benchmark.
Optimization by searching a tree of populations

GAs have been found to be useful in handling many numerical optimization problems. Because of the variability in results inherent in the stochastic nature of GAs, it is common to run a GA several times and take the best of the results. However, it is possible to save a GA's population at some intermediate states and restart from one of these populations instead of from the very beginning. By doing so we generate a tree of populations, where a child population is generated from its parent by running some number of GA iterations. We describe two methods for searching such a tree of populations, one based on Highest Utility First Search (HUFS) and one that proceeds level by level with no backtracking, and give the results of testing them on a real-world optimization task involving conceptual design of supersonic transport aircraft. They both do much better than repeatedly running the GA from the beginning, with HUFS achieving equivalent results in less than half the GA iterations in some situations.
Reassembling Scattered and Mixed Human Bones by Trace Element Ratios

Trace metal ratios in human bones were examined to determine if there were ratios that were sufficiently consistent within an individual yet varying sufficiently from the bones of another individual so that bones in a mixed grave could be reassembled. The concentrations of 21 elements sampled at 54 places on 30 human bones in each of 5 skeletons indicated that the magnesium/zinc ratio was the most reliable and that the zinc/sodium, magnesium/sodium, and chromium/sodium ratios could be used as supplements to help reassemble human bones belonging to the same individual after all standard techniques had been used.
What Is Convergence Acceleration Anyway

The concept of convergence acceleration is presented through two examples of its application to very different physics. The first is for self-assembly of misfolded proteins described by moments of the filament length distribution. With convergence acceleration, highly accurate moments can be found, as confirmed by a manufactured solution, leading to a more accurate estimate of spongiform disease onset. The second application considers the transient behavior of a nuclear reactor. Here, the reactor kinetics equations (RKE) are solved to extreme accuracy as demonstrated by comparison to analytical and manufactured solutions. From our investigation, we conclude that with some added initiative and effort, extreme accuracy in a numerical computation involving discretization is achievable through convergence acceleration.
Multiculturalism and Identity Politics: Cultural Concerns

Multiculturalism is a social perspective that is committed to publicly recognizing and respecting many cultures and cultural identities. Identity politics is one means by which members of a society strive for public recognition of their cultures and cultural identities. One conception of multiculturalism that animates identity politics is that people primarily identify as members of groups defined by ethnicity, race, gender, religion, or sexual orientation, and therefore can be expected to pressure their government for greater positive political recognition of, and public benefits for, their own group. Another conception of multiculturalism is critical of identity politics because it rejects the idea of a one-to-one correspondence between a person and a particular cultural identity, and views individual identities as themselves multicultural. Although societies have long been multicultural, the use of multiculturalism as a term in social and political discourse is relatively recent. Three kinds of multiculturalism can be identified as coexisting in the same society: ethnic, linguistic, and national multiculturalism. Different perspectives on various dimensions of multiculturalism—personal identity, public recognition, and standards of assessment—help elucidate the controversies that multiculturalism generates and the policies that it supports.
The 'Bulgarian Situation': Constructing the Myth of a 'National Mentality' in Bulgarian Discourse and its Effect on Agency

ABSTRACTThis study examines the mythic form of the ‘Bulgarian situation’,which is evoked and managed in moments of social interaction,and during enactments of oplakvane (complaining) in Bulgarian discourse. Based on ethnographic examination of naturally occurring talk, interviews, and various media data, the article constructs the larger cultural narrative available in Bulgarian discourse,which explains the origins of a national identity,linked to a ‘national mentality’ developed over a historical period.This national identity is constituted communication, and highlights a deeply cultural notion of nationality and biology as intricately connected, and developed in the context of the Ottoman occupation,and the following period of socialism. Such a discursive conceptualization of nationality has implications for the local understandings of self and agency, also visible in a larger field of study across disciplines in Bulgaria under the name narodopsihologij (national psychology). The study bridges areas of ...
USE OF A GASTROSTOMY AND JEJUNOSTOMY TUBE FOR MANAGEMENT OF GASTRIC DISTENTION FOLLOWING PYLORIC OUTFLOW OBSTRUCTION IN A FERRET (MUSTELA PUTORIUS FURO)

Abstract An 8-month-old spayed female ferret (Mustela putorius furo) was presented for evaluation of persistent, severe gastric distention following gastrotomy to retrieve several foreign bodies. A structural cause of gastric outflow obstruction was not identified ultrasonographically or surgically. A 14 Fr gastrostomy and an 8 Fr jejunostomy tube were used to facilitate medical management of severe gastric stasis and to allow enteral nutrition. The ferret tolerated the feeding tubes well and recovered completely following intensive medical therapy. This report describes successful management of idiopathic gastric distention using gastric and jejunal feeding tubes in a ferret. Feeding tubes and supplemental nutrition plans should be considered for management of ferrets with compatible disease processes.
Measurement of Energy Metabolism in Explanted Retinal Tissue Using Extracellular Flux Analysis

High acuity vision is a heavily energy-consuming process, and the retina has developed several unique adaptations to precisely meet such demands while maintaining transparency of the visual axis. Perturbations to this delicate balance cause blinding illnesses, such as diabetic retinopathy. Therefore, the understanding of energy metabolism changes in the retina during disease is imperative to the development of rational therapies for various causes of vison loss. The recent advent of commercially-available extracellular flux analyzers has made the study of retinal energy metabolism more accessible. This protocol describes the use of such an analyzer to measure contributions to retinal energy supply through its two principle arms - oxidative phosphorylation and glycolysis - by quantifying changes in oxygen consumption rates (OCR) and extracellular acidification rates (ECAR) as proxies for these pathways. This technique is readily performed in explanted retinal tissue, facilitating assessment of responses to multiple pharmacologic agents in a single experiment. Metabolic signatures in retinas from animals lacking rod photoreceptor signaling are compared to wild-type controls using this method. A major limitation in this technique is the lack of ability to discriminate between light-adapted and dark-adapted energy utilization, an important physiologic consideration in retinal tissue.
Estimating Queue Length Under Connected Vehicle Technology: Using Probe Vehicle, Loop Detector, and Fused Data

With the emergence of connected vehicle technology, the use of probe trajectory data to estimate queue length has recently received considerable attention. Unlike data collected by loop detectors, probe trajectory data can provide a lower bound on the queue length even if the market penetration rate is low. An event-based method is developed: it uses both probe trajectory and signal timing data to estimate queue length, and the estimation accuracy under different market penetration rates is examined. A data fusion method is developed: it combines probe trajectory data and loop detector data, and the situation in which the data fusion method is expected to work well is investigated. Case studies are conducted with microscopic simulation data, and some observations are made.
2192-P: Extracellular Vesicles as Novel Mediators of Proinflammatory Cytokine-Induced ß-Cell Dysfunction

The presence of a proinflammatory islet microenviroment and consequent dysregulation of glucose-stimulated insulin secretion (GSIS) is a hallmark feature of both type 1 and type 2 diabetes. Recent evidence has implicated islet cell-derived extracellular vesicles (EVs) as novel mediators of cytokine-derived inflammatory stress in diabetes, however the mechanisms governing this process remain largely unknown. Therefore, we set out to test the hypothesis that cytokine-mediated β-cell dysfunction is mediated in part through β-cell autocrine release of proinflammatory EVs which promote inflammation and inhibit GSIS. Particle size analysis of EVs from conditioned media of cytokine treated (IL-1β, TNF-α, and IFNγ) Min6 β-cells (CytoEV) showed an overall increase in β-cell EV secretion (∼2 fold increase, P Disclosure N. Javeed: None. T.K. Her: None. P.M. Vanderboom: None. I.R. Lanza: None. A. Matveyenko: None.
Thermal Diffusivity Measurement of Diamond Materials

The thermal wave/mirage effect technique is applied to the determination of thermal properties of polycrystalline diamond slabs and single crystal diamonds of different isotopic compositions. This method is well-suited for these kinds of materials.
Determinants of Capital Structure: An Expanded Assessment

Using a standardized methodology, we empirically evaluate 56 determinants of capital structure proposed in the literature in terms of economic significance, statistical significance, identification, and intertemporal stability. We organize the determinants into a framework in which each proposed determinant represents a constraint on shareholder value maximization in interactions with specific related parties. We find that truly robust and economically important determinants of debt ratios are relatively few in number. However, the evidence as a whole shows that the strongest determinants are those related to shareholder interactions with prospective equityholders and debtholders.
Probingintermediate-mass black holes in M87 through multiwavelength gravitational wave observations

We analyze triple systems composed of the super massive black hole (SMBH) near the center of M87 and a pair of black holes (BHs) with masses in the range $10-10^3$ $M_{\odot}$. We consider the post Newtonian precession as well as the Kozai-Lidov interactions at the quadruple and octupole levels in modeling the evolution of binary black hole (BBH) under the influence of the SMBH. Kozai-Lidov oscillations enhance the gravitational wave (GW) signal in some portions of the parameter space. We identify frequency peaks and examine the detectability of GWs with LISA as well as future observatories such as $\mu$Ares and DECIGO. We show examples in which GW signal can be observed with a few or all of these detectors. Multi-Wavelength GW spectroscopy holds the potential to discover stellar to intermediate mass BHs near the center of M87. We estimate the rate, $\Gamma$, of collisions between the BBHs and flyby stars at the center of M87. Our calculation suggests $\Gamma < 10$ $\rm{Gyr}^{-1}$ for a wide range of the mass and semi-major axes of the inner binary.
‘Nondemocratic Islamists’ and support for ISIS in the Arab World

Are proponents of Islamic government in the Arab World more likely to support violent extremist groups like ISIS? Previous research indicates that the answer to this question is dependent on indivi...
It’s Not Rational It’s Complicated: Latina Mothers’ Choices of Childcare

In order to understand Latina mothers’ choices of childcare for their children ages birth to five, a qualitative study of 42 Latina mothers (ages 18 to 43) from Southern California was conducted. R...
Understanding Advance Directives as a Component of Advance Care Planning.

Walsh (2020) presents an argument against what she calls the received view of advance directives in the philosophical literature, suggesting instead a view that she believes is supported by “real c...
Abstract 3907: Invasive properties of GSCs with known IDH1 status into human cerebral organoids

Glioblastomas (GBM) are malignant Grade IV tumors whose prognosis for patients remains dismal, with median survival of 14.6 months after the standard therapy. GBMs have a high proliferative index and are highly invasive to normal brain tissue. GBMs characteristically exhibit areas of necrosis and recruitment of abnormal blood vessels. The most common form of GBMs are primary GBMs (~95%), with no prior clinical history and have poor clinical outcome. Secondary GBMs arise from lower-grade gliomas and are associated with IDH1 mutation (R132H/C/G/S). Methylation profiling identified a subtype of GBMs called glioma-CpG island methylator phenotype (G-CIMP+ve) GBMs, and this subtype yields significant survival benefit compared to non-G-CIMP+ve GBMs and is mostly associated with IDH1 mutant GBMs. GBM biology is traditionally investigated by utilizing patient-derived tumor cells (e.g GBM stem-like cells “GSCs”) in vitro and in vivo as orthotopic xenografts in immunocompromised mouse models. However, these systems lack normal human neural tissue, and therefore the contribution of the normal human neural microenvironment is unable to be studied using these systems. This shortcoming can be addressed by utilizing human cerebral organoids (COs). Cerebral organoids are derived from induced pluripotent stem cells and can serve as in vitro model systems to recapitulate the human brain microenvironment where multiple neural cell types are represented. A recent study showed that GSCs invade and proliferate in human cerebral organoids, and these tumors phenocopy parental tumors. Here, we hypothesized that the invasiveness of GSCs within COs is dictated by IDH1 status, where IDH1 wild-type are more aggressive than IDH1 mutant GSCs. To test our hypothesis, we utilized 45 day-old COs and three GSCs lines (2 IDH1 wild-type and 1 IDH1 mutant) for in vitro invasion and proliferation assays. These GSCs stably express either green or red fluorescent proteins and can be used as surrogates to identify GSCs within COs. Upon co-incubation for various time points, these GSC bearing COs were fixed, embedded, sectioned, and imaged with a confocal microscope. Our preliminary results show that GSCs with wild-type IDH1 appear to be more aggressive within COs. With further research studies, the use of COs will elucidate the contribution of the normal brain microenvironment to the growth and invasiveness of GBMs. Citation Format: Maxime Munyeshyaka, Sanjay Singh, Joy Gumin, Jing Yang, Daniel Ledbetter, Frederick Lang. Invasive properties of GSCs with known IDH1 status into human cerebral organoids [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 3907.
Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids

Three-dimensional (3D) cell culture technologies, such as organoids, are physiologically relevant models for basic and clinical applications. Automated microfluidics offers advantages in high-throughput and precision analysis of cells but is not yet compatible with organoids. Here, we present an automated, high-throughput, microfluidic 3D organoid culture and analysis system to facilitate preclinical research and personalized therapies. Our system provides combinatorial and dynamic drug treatments to hundreds of cultures and enables real-time analysis of organoids. We validate our system by performing individual, combinatorial, and sequential drug screens on human-derived pancreatic tumor organoids. We observe significant differences in the response of individual patient-based organoids to drug treatments and find that temporally-modified drug treatments can be more effective than constant-dose monotherapy or combination therapy in vitro. This integrated platform advances organoids models to screen and mirror real patient treatment courses with potential to facilitate treatment decisions for personalized therapy.
Low-Temperature Molten Sodium Batteries

Low-temperature molten sodium batteries show remarkable promise as the kind of low-cost, large-scale, reliable energy storage technology which is key to enabling a sustainable, safe, and resilient ...
Atomistic Simulations of Strain Rate Dependent Deformation Behavior at Continuum Timescales

A majority of computational mechanical analyses of nanocrystalline materials or nanowires have been carried out using classical molecular dynamics (MD). Due to the fundamental reason that the MD simulations must resolve atomic level vibrations, they cannot be carried out at a timescale of the order of microseconds. Additionally, MD simulations have to be carried out at very high loading rates (~108 s−1) rarely observed during experiments. In this investigation, a modified Hybrid Monte Carlo (HMC) method that can be used to analyze time-dependent (strain rate dependent) atomistic mechanical deformation of nanostructures at continuum timescales is established. In this method there is no restriction on the size of MD timestep except that it must be such that to ensure a reasonable acceptance rate between consecutive Monte-Carlo (MC) time-steps. For the purpose of comparison HMC analyses of a Cu nanowire deformation at two different strain rates (108 s−1 and 109 s−1) (each with three different timesteps 2 fs, 4fs, and 8 fs) are compared with the analyses based on MD simulations at the corresponding strain rates with the MD timestep of 2 fs. As expected, the defect formation in the Cu nanowire is found to be strain rate dependent. In addition, HMC with a timestep of 8 fs correctly reproduced defect formation and stress-strain response observed in the case of MD with a timestep of 2 fs (for the interatomic potential used, 2 fs is the maximum permissible MD timestep). Simulation time analyses show that by using HMC an order of 4 savings in computational time can be achieved bringing the atomistic analyses closer to the continuum timescales.
Large-Scale System Analysis Under Uncertainty: With Electric Power Applications

Discover a comprehensive set of tools and techniques for analyzing the impact of uncertainty on large-scale engineered systems. Providing accessible yet rigorous coverage, it showcases the theory through detailed case studies drawn from electric power application problems, including the impact of integration of renewable-based power generation in bulk power systems, the impact of corrupted measurement and communication devices in microgrid closed-loop controls, and the impact of components failures on the reliability of power supply systems. The case studies also serve as a guide on how to tackle similar problems that appear in other engineering application domains, including automotive and aerospace engineering. This is essential reading for academic researchers and graduate students in power systems engineering, and dynamic systems and control engineering.
Writing and Praying Collects as an Intervention in Narrative Therapy

The integration of spiritual practices in therapy is a valuable tool for supporting and reinforcing change. This paper explores the use of a written form of prayer called a collect as an intervention in narrative therapy. A collect is a form of prayer with a structure that can be easily co-constructed by clients and therapists. This spiritual intervention serves as a therapeutic document to help reinforce the externalization of a client’s problem or help thicken alternative narratives. Relevant aspects of narrative therapy and written prayer are summarized. A guide for implementation, examples of collects, and a worksheet for helping clients write collects is provided.
Source Separation and Depthwise Separable Convolutions for Computer Audition (Student Abstract)

Given recent advances in deep music source separation, we propose a feature representation method that combines source separation with a state-of-the-art representation learning technique that is suitably repurposed for computer audition (i.e. machine listening). We train a depthwise separable convolutional neural network on a challenging electronic dance music (EDM) data set and compare its performance to convolutional neural networks operating on both source separated and standard spectrograms. It is shown that source separation improves classification performance in a limited-data setting compared to the standard single spectrogram approach.
Made in Yugoslavia: Studies in Popular Music

Made in Yugoslavia: Studies in Popular Music (edited by Danijela Spiric Beard and Ljerka Rasmussen) is a fascinating study of how popular music developed in post-World War II Yugoslavia, eventually reaching both unsurpassable popularity in the Balkans and Eastern Europe, and critical acclaim in the West. Through the comprehensive discussion of all popular music trends in Yugoslavia − commercial pop (zabavna-pop), rock, punk, new wave, disco, folk (narodna), and neofolk (novokomponovana) − across all six socialist Yugoslav republics, the reader is given the engrossing socio-cultural and political history of the country, providing the audience with a much-needed and riveting context for understanding the formation and the eventual demise of Tito’s Yugoslavia.
Hydrogen-peroxide generating electrochemical bandage is active in vitro against mono- and dual-species biofilms.

Abstract Biofilms formed by antibiotic-resistant bacteria in wound beds present unique challenges in terms of treating chronic wound infections; biofilms formed by one or more than one bacterial species are often involved. In this work, the in vitro anti-biofilm activity of a novel electrochemical bandage (e-bandage) composed of carbon fabric and controlled by a wearable potentiostat, designed to continuously deliver low amounts of hydrogen peroxide (H2O2) was evaluated against 34 mono-species and 12 dual-species membrane bacterial biofilms formed by Staphylococcus aureus, S. epidermidis, Enterococcus faecium, E. faecalis, Streptococcus mutans, Escherichia coli, Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, Cutibacterium acnes, and Bacteroides fragilis. Biofilms were grown on polycarbonate membranes placed atop agar plates. An e-bandage, which electrochemically reduces dissolved oxygen to H2O2 when polarized at −0.6 VAg/AgCl, was then placed atop each membrane biofilm and polarized continuously for 12, 24, and 48 h using a wearable potentiostat. Time-dependent decreases in viable CFU counts of all mono- and dual-species biofilms were observed after e-bandage treatment. 48 h of e-bandage treatment resulted in an average reduction of 8.17 ± 0.40 and 7.99 ± 0.32 log10 CFU/cm2 for mono- and dual-species biofilms, respectively. Results suggest that the described H2O2 producing e-bandage can reduce in vitro viable cell counts of biofilms grown either in mono- or dual-species forms, and should be further developed as a potential antibiotic-free treatment strategy for treating chronic wound infections.
An Engagement of Hope: A Framework and Equity-Centered Theory of Action for Community Engagement

Building upon the proposed concept of an engagement of hope (Green, Stewart, Bergen, & Nayve, 2020) emerging from the exploration of faith-based approaches to community engagement, the authors delve into collaborative inquiry and critical reflection to construct a framework and equity-centered theory of action for community engagement. Drawing from the work of faith-based community organizations and institutions of higher education, and through the lens of a practitioner-scholar framework, the authors present a scholarly approach to collaborative inquiry and exploration into an engagement of hope, responding to the current context of higher education. The development of the engagement of hope conceptual framework emerged with core approaches to community engagement, responding to the current context and seeking to move the field of community engagement to address this context. The five themes that scaffold the conceptual framework are explicated, including challenging unjust structures, the common good, collaborative courage, community-centered, and individual goodness. The implications of this framework and theory of change are discussed as well as a call to re-center relationships in the community engagement field.
Myasthenia gravis: identification of skeletal and heart muscle antigens not related to the acetylcholine receptor

Abstract Myasthenia gravis (MG) is a neuromuscular disease thought to have an autoimmune etiology. The acetylcholine receptor has been considered the primary site of antibody binding; however, other muscle components may be involved in the pathogenesis of myasthenia gravis. This study describes a hypertonic sucrose extract of skeletal muscle (Muscle-HSE) that reacts with antibodies in myasthenic sera. The active component in Muscle-HSE is not the acetylcholine receptor as demonstrated by the inability of this extract to bind [125I]α-bungarotoxin. Muscle-HSE does, however, contain two distinct antigenic components reactive with MG sera. One antigen reacted with 70% ( 14 20 ) of myasthenic sera in the passive hemagglutination assay. This antigen was detected in the HSE of both skeletal muscle and heart, and was unaffected by treatment with Triton X-100. The second antigen reacted with 10% ( 2 20 ) of MG sera in the complement fixation assay, was unique to skeletal muscle, and was inactivated by Triton X-100.
Congenital cytomegalovirus infection.

Abstract Five cases of congenital cytomegalovirus infection are presented. In the three cases studied by virologic and immunologic techniques, it was demonstrated that complement-fixing antibody titers are low in contrast to the postnatally acquired infection. In 2 of the 3 cases the quantitative immunodiffusion titers for IgM immunoglobulins were not elevated. The lack of an adequate serologic test for congenital cytomegalovirus infection and the failure of an absolute correlation between elevated quantitative IgM levels and congenital infection stress the essentiality of virus isolation techniques as well as clinical acuity in delineating the natural history of congenital cytomegalovirus infection.
Simulation and Measurement of the Los Alamos 94GHz TWT RF Structure

LANL has developed a new vane loaded waveguide RF structure for a sheet beam TWT. The goal was to create a new class of wideband RF structures that allow simple mechanical fabrication and have geometry suitable for interaction with sheet electron beams. LANL has developed an RF structure using planar geometry for simple EDM machining at 94GHz .Structure gain was demonstrated with a 2A pencil beam.
Peptic ulcer disease, hyperparathyroidism, and pituitary tumor.

A 41-year-old man consulted his physician because of refractory peptic ulcer disease. Routine laboratory studies revealed mild hypercalcemia (10.7 mg/dL). A pituitary tumor was removed 10 years earlier. Ultrasound and computed tomography (CT) images are shown below (Figures ​(Figures11–4). Figure 1 Ultrasound image demonstrates a left superior parathyroid mass (arrows 12 mm in maximum dimension. Figure 4 Enhanced CT (arterial phase) shows an enhancing mass (arrows), 1cm in diameter, in the tail of the pancreas. For diagnosis and discussion, see the following page. DIAGNOSIS: Multiple endocrine neoplasia (MEN), type 1.
Double Atrial Septal Defect: Diagnosis and Closure Guidance with 3D Transesophageal Echocardiography

Atrial septal defect (ASD) is a common form of congenital heart disease that often persists well into adulthood before discovery or intervention. The authors report the case of a patient referred for routine percutaneous ASD closure that was found on three-dimensional (3D) transesophageal echocardiography to have two large separate ostium secundum defects which were subsequently closed under 3D echocardiographic guidance. (Echocardiography 2011;28:E115-E117)
Science policy. The NIH budget in the "postdoubling" era.

The 5-year doubling of the NIH budget represents a bold policy decision to reset the level of public investment in biomedical research. The authors propose 6 principles to guide NIH spending in coming years that would protect that investment by balancing support for new research with respect for prior commitments and national research capacity. The goal is a sustainable biomedical research enterprise that avoids destabilizing, counterproductive gyrations in funding. Modeling of NIH budget scenarios reflecting these principles indicates that growth rates below the historic average of the past 4 decades would quickly negate the advantages achieved by the doubling initiative.
Student and Parent Attitudes Before and After the Gifted Identification Process

Questionnaires were given to students prior to testing for giftedness to assess how the gifted identification process changes attitudes to ward gifted programs and parent-child relationships. After those identified as gifted had been participating in a pullout gifted program for one semester, another questionnaire was administered to all original participants. Comparable data were also collected from the students' parents. Results suggest that prior to identification, gifted and nongifted students and their parents shared similar attitudes toward giftedness. After identification, attitudes showed either no change or decreased. Compared to their gifted counterparts, nongifted students and their parents tended to report lower attitudes after identification. The impact of this attenuation and the use of preidentification data are also discussed.
Computing in everyday life: a call for research on experiential computing

The information systems field emerged as a new discipline of artificial science as a result of intellectual efforts to understand the nature and consequences of computer and communication technology in modern organizations. As the rapid development of digital technology continues to make computers and computing a part of everyday experiences, we are once again in need of a new discipline of the artificial. In this essay, I argue that the IS community must expand its intellectual boundaries by embracing experiential computing as an emerging field of inquiry in order to fill this growing intellectual void. Experiential computing involves digitally mediated embodied experiences in everyday activities through everyday artifacts that have embedded computing capabilities. Experiential computing is enabled by the mediation of four dimensions of human experiences (time, space, actors, and artifacts) through digital technology. Drawing on a research framework that encompasses both behavioral and design sciences, six research opportunities that the IS research community can explore are suggested. Ultimately, I propose that the IS field return to its roots, the science of the artificial, by decisively expanding the scope of its inquiry and establishing a new domain of research on computing in everyday life experiences.
Bad Parts: Are Our Manufacturing Systems at Risk of Silent Cyberattacks?

Recent cyberattacks have highlighted the risk of physical equipment operating outside designed tolerances to produce catastrophic failures. A related threat is cyberattacks that change the design and manufacturing of a machine's part, such as an automobile brake component, so it no longer functions properly.
Intragenic Suppressors of Dictyostelium Myosin G680 Mutants Demarcate Discrete Structural Elements: Implications for Conformational States of the Motor

We are using intragenic suppression to generate inferences about currently inaccessible conformations of the molecular motor myosin. We identified 19 unique suppressors of Dictyostelium G680A and G680V mutants and find that they are structurally and chemically restricted, suggestive of specific, compensatory mechanisms of action. Suppressors cluster in two adjacent elements of the myosin structure, one of which is dominated by substitutions that increase the volume of hydrophobic residues. The suppressors outline a general model for the mechanism of suppression of the G680A and G680V alterations. Secondary phenotypes conferred by suppressors independent of the G680 changes demonstrate that they will be useful substrates for biochemical and genetic characterization.
The Regulatizing Process and the Boundaries of New Public Governance

New Public Governance is one of the most significant intellectual movements in the theory of government to have emerged in the past few decades. It suggests that regulators should develop a more modulated, cooperative approach to the task of achieving compliance with regulatory programs, rather than relying on the adversarial stance that characterizes command and control regulation. This speaks directly to the concerns about regulation that have raised by both scholars and elected officials, and that may provide a model for the Obama Administration’s strategy in this important area. The question is when the recommendations of New Public Governance are likely to be most effective, and when they should be treated with caution. This paper advances an answer based on the social theory of Norbert Elias ("The Civilizing Process,” 1939). One feature of Elias’ theory is its suggestion that regulation is not a static process for which one temporally independent approach will be optimal, but a dynamic one that changes and evolves, which means that different approaches will be optimal at different stages of the process. The paper illustrates the applicability of Elias’ theory - and the advantages of a dynamic theory of regulation in general - by using the example of commercial airline regulation. It concludes that the effectiveness of a New Public Governance approach is likely to increase as regulated parties become more accustomed to, and accepting toward, the regulatory framework.
High-density blue-laser rewritable optical disc system adopting 0.3-mm-thick plastic substrate

Continuing demands for higher-capacity optical disc storage system become even stronger as High-Definition TV Broadcasting and Internet are creating new needs for data storage. Recently, high density optical disc systems using blue laser diodes have been reported as potential candidates for next generation industry-standard. At ISOM/ODSi '99, we have proposed to reduce substrate thickness to 0.3 mm, and showed its potential advantage by read-out test using blue laser diode. Later, we reported experimental results of read-only and rewritable disc systems based on the 0.3 mm plastic injection-molded substrate. In this paper, we will report on some of the new features of our blue wavelength system as well as the technical progress we have achieved so far.
Association of crossword puzzle participation with memory decline in persons who develop dementia

Participation in cognitively stimulating leisure activities such as crossword puzzles may delay onset of the memory decline in the preclinical stages of dementia, possibly via its effect on improving cognitive reserve. We followed 488 initially cognitively intact community residing individuals with clinical and cognitive assessments every 12-18 months in the Bronx Aging Study. We assessed the influence of crossword puzzle participation on the onset of accelerated memory decline as measured by the Buschke Selective Reminding Test in 101 individuals who developed incident dementia using a change point model. Crossword puzzle participation at baseline delayed onset of accelerated memory decline by 2.54 years. Inclusion of education or participation in other cognitively stimulating activities did not significantly add to the fit of the model beyond the effect of puzzles. Our findings show that late life crossword puzzle participation, independent of education, was associated with delayed onset of memory decline in persons who developed dementia. Given the wide availability and accessibility of crossword puzzles, their role in preventing cognitive decline should be validated in future clinical trials.