cssi/SciSciGPT-SciSciNet huggingface dataset:
A Low-Cost, Grab-and-Go Breakfast Intervention for Rural High School Students: Changes in School Breakfast Program Participation Among At-Risk Students in Minnesota

Abstract Objective Evaluate the impact of a grab-and-go component embedded within a larger intervention designed to promote School Breakfast Program (SBP) participation. Design Secondary data analysis. Setting Rural Minnesota high schools. Participants Eight schools were enrolled in the grab-and-go only intervention component. An at-risk sample of students (n = 364) who reported eating breakfast ≤3 d/wk at baseline was enrolled at these schools. Interventions Grab-and-go style breakfast carts and policies were introduced to allow all students to eat outside the cafeteria. Main Outcome Measures Administrative records were used to determine percent SBP participation (proportion of non-absent days on which fully reimbursable meals were received) for each student and school-level averages. Analysis Linear mixed models. Results School-level increases in SBP participation from baseline to the school year of intervention implementation were observed for schools enrolled in the grab-and-go only component (13.0% to 22.6%). Student-level increases in SBP participation were observed among the at-risk sample (7.6% to 21.9%) and among subgroups defined by free- or reduced-price meal eligibility and ethnic or racial background. Participation in SBP increased among students eligible for free or reduced-price meals from 13.9% to 30.7% and among ineligible students from 4.3% to 17.2%. Conclusions and Implications Increasing access to the SBP and social support for eating breakfast are effective promotion strategies.
Risk of peritoneal dialysis catheter-associated peritonitis following kidney transplant.

Objective Peritoneal dialysis (PD) patients have equivalent or slightly better kidney transplant outcomes when compared to hemodialysis (HD) patients. However, given the risk for postoperative infection, we sought to determine the risk factors for PD catheter-associated infections for patients who do not have the PD catheter removed at the time of engraftment. Methods Demographic and outcomes data were collected from 313 sequential PD patients who underwent kidney transplant from 2000 to 2015. Risk factors for postoperative peritonitis were analyzed using logistical regression. Results Of 329 patients with PD catheters at transplant, 16 PD catheters were removed at engraftment. Of the remaining 313 patients, 8.9% suffered post-transplant peritonitis. On univariate analysis, patients with peritonitis were significantly more likely to have used the PD catheter or HD within 6 weeks after transplant. Multivariate analysis had similar findings, with increased risk for those using the PD catheter after transplant, with a trend for those who underwent HD only within 6 weeks of transplant. Conclusion These results suggest that delayed graft function requiring any type of dialysis is associated with increased post-transplant peritonitis risk.
Developing a Culture Change Person-Centered Environment

Culture change “is the common name given to the national movement for the transformation of older adult services, based on person-directed values and practices where the voices of elders and those working with them are considered and respected. Core person-directed values are choice, dignity, respect, self-determination and purposeful living.” (Pioneer Network 2017a, para 2).
The Effect of Implicit versus Explicit Comparisons on Temporal Pricing Claims

Existing research has investigated the "pennies-a-day" strategy of reframing an "aggregate" expense as a "per day" expense (Nagle & Holden, 1995; Price 1995; Gourville 1998). This paper extends this research by considering the incremental impact on compliance of explicitly comparing the cost of a transaction to a specific petty cash expense (e.g., a cup of coffee). We show that in the presence of a ‘per day’ framing of price (e.g., $1 per day), an explicit comparison provides little added value. However, we also show that in the presence of an ‘aggregate’ framing of price (e.g., $350), an explicit comparison to a petty cash expense is sufficient to generate a "pennies-a-day" perspective. We conclude that it is not the ‘per day’ framing, per se, which drives "pennies-a-day" effectiveness, but the petty cash comparisons that such a framing either implicitly or explicitly generates.
An actin-depolymerizing factor from the halophyte smooth cordgrass, Spartina alterniflora (SaADF2), is superior to its rice homolog (OsADF2) in conferring drought and salt tolerance when constitutively overexpressed in rice.

Actin-depolymerizing factors (ADFs) maintain the cellular actin network dynamics by regulating severing and disassembly of actin filaments in response to environmental cues. An ADF isolated from a monocot halophyte, Spartina alterniflora (SaADF2), imparted significantly higher level of drought and salinity tolerance when expressed in rice than its rice homologue OsADF2. SaADF2 differs from OsADF2 by a few amino acid residues, including a substitution in the regulatory phosphorylation site serine-6, which accounted for its weak interaction with OsCDPK6 (calcium-dependent protein kinase), thus resulting in an increased efficacy of SaADF2 and enhanced cellular actin dynamics. SaADF2 overexpression preserved the actin filament organization better in rice protoplasts under desiccation stress. The predicted tertiary structure of SaADF2 showed a longer F-loop than OsADF2 that could have contributed to higher actin-binding affinity and rapid F-actin depolymerization in vitro by SaADF2. Rice transgenics constitutively overexpressing SaADF2 (SaADF2-OE) showed better growth, relative water content, and photosynthetic and agronomic yield under drought conditions than wild-type (WT) and OsADF2 overexpressers (OsADF2-OE). SaADF2-OE preserved intact grana structure after prolonged drought stress, whereas WT and OsADF2-OE presented highly damaged and disorganized grana stacking. The possible role of ADF2 in transactivation was hypothesized from the comparative transcriptome analyses, which showed significant differential expression of stress-related genes including interacting partners of ADF2 in overexpressers. Identification of a complex, differential interactome decorating or regulating stress-modulated cytoskeleton driven by ADF isoforms will lead us to key pathways that could be potential target for genome engineering to improve abiotic stress tolerance in agricultural crops.
Radioactive Microspheres for Medical Applications

This paper reviews the preparation and application of radioactive microspheres for medical purposes. It first discusses the properties of relevant radioisotopes and then explores the diagnostic uses of gamma-emitter labelled microspheres, such as blood flow measurement and imaging of the liver and other organs. The therapeutic uses of alpha- and beta-emitting microspheres, such as radioembolization, local tumour therapy and radiosynovectomy, are then described, and the recent developments in neutron capture therapy using gadolinium microspheres and boron liposomes discussed. The review concludes with some considerations in radiopharmaceutical kit preparations and radioisotope generator use, as well as with some radiobiological and dosimetric concerns.
Nutritional Requirements for Growth in Children with Renal Insufficiency

Optimum requirements for growth in normal children are defined by the Recommended Dietary Allowances (RDAs) (National Research Council, Food and Nutrition Board, 1980). Given access to adequate food, it is assumed that normal children will have an appetite that assures an adequate intake of energy. Requirements for specific nutrients other than energy are usually met when children satisfy appetite for calories with customary foods. Specific nutrients are taken well in excess of RDA and, in many instances, the excess is excreted in urine. Dietary tolerances are generous in normal children (Holliday, 1976).
Elastic plastic mode III crack under internal shear

A complete solution is presented for the problem of a mode III crack in an infinite elastic perfectly-plastic solid under internal shear stress. This problem is the anti-plane strain equivalent of a mode I crack with internal pressure. The problem is transformed into a boundary value problem for a potential function. The particular case when the applied stress σA is equal to the yield stress σ0 is solved analytically, and the distance to the elastic-plastic boundary is obtained in closed form. The general case when σA σ0 is solved numerically by using the Boundary Element Method for potential problems. Numerical results are given for the distance to the elastic-plastic boundary and the crack tip opening displacement. The extent of the plastic zone ahead of the crack tip is shown to vary linearly with the ratio σA/σ0) when 0.5 ≤ (σA/σ0) ≤ 1.
An Analysis of the Thermal Behavior of a Stagnant Pool for Fast Reactor Safety

This paper analyzes the radial progression of a pool of molten reactor material that might form in a liquid-metal fast breeder reactor (LMFBR) experiencing an accident. An assessment of the thermal interaction of the molten material with its steel containment is made. The thermal response of molten UO/sub 2/ and molten UC pools was examined prior to their boilup and their dependence on steel content, porosity, and internal heat generation in the pool, as well as the heat convection rate at the outer boundary of the container, was determined. A preliminary feasibility study was presented illustrating the importance of heating rate in the pellet, radial power profile, and the heat transfer coefficient at the container outer boundary. 23 refs.
Galantamine alleviates inflammation and other obesity-associated complications in high-fat diet-fed mice.

Obesity, a serious and growing health threat, is associated with low-grade inflammation that plays a role in mediating its adverse consequences. Previously, we have discovered a role for neural cholinergic signaling in controlling inflammation, and demonstrated that the cholinergic agent galantamine suppresses excessive proinflammatory cytokine release. The main objective of this study was to examine the efficacy of galantamine, a clinically-approved drug, in alleviating obesity-related inflammation and associated complications. After 8 wks on a high-fat diet, C57BL/6J mice were treated with either galantamine (4 mg/kg, intraperitoneally (i.p.)) or saline for 4 wks in parallel with mice on a low-fat diet and treated with saline. Galantamine treatment of obese mice significantly reduced body weight, food intake, abdominal adiposity, plasma cytokine and adipokine levels, and significantly improved blood glucose, insulin resistance and hepatic steatosis. In addition, galantamine alleviated impaired insulin sensitivity and glucose intolerance significantly. These results indicate a previously unrecognized potential of galantamine in alleviating obesity, inflammation and other obesity-related complications in mice. These findings are of interest for studying the efficacy of this clinically-approved drug in the context of human obesity and metabolic syndrome.
A Wildland and Woodland Vision for the New England Landscape: Local Conservation, Biodiversity and the Global Environment

Most arguments that start “think globally/act locally” struggle to forge a convincing connection between these two scales of action. However, for New England and most of the eastern United States there is a direct link between effective forest protection and management and the global environment. As a consequence of sub-continental reforestation and growth since the 19th Century, residents across this region have a second chance to determine the fate of their natural landscape. The forests that blanket this region are young and growing rapidly, storing globally important amounts of carbon and thereby thwarting global climate change. Protecting these forests and managing them to generate products and store additional carbon will bring immense benefits to local communities and the world. The Wildlands and Woodlands proposal to protect and manage 50% of southern New England in forests provides a mechanism for achieving such ambitious local and global goals.
Applying the RE-AIM Framework for the Evaluation of a Clinical Decision Support Tool for Pediatric Head Trauma: A Mixed-Methods Study.

Background The overuse of cranial computed tomography (CT) to diagnose potential traumatic brain injuries (TBIs) exposes children with minor blunt head trauma to unnecessary ionizing radiation. The Pediatric Emergency Care Applied Research Network and the Clinical Research on Emergency Services and Treatments Network implemented TBI prediction rules via electronic health record (EHR) clinical decision support (CDS) to decrease use of CTs in children with minor blunt head trauma. Objective This article aims to facilitate implementation and dissemination of a CDS alert into emergency departments around the country. Methods We evaluated the EHR CT CDS tool through a mixed-methods analysis of 38 audio-recorded interviews with health care stakeholders and quantitative data sources, using the Reach, Efficacy, Adoption, Implementation, and Maintenance framework. Results Reach —The demographics of participants enrolled in the clinical trial were consistent with national estimates of TBI prevalence. Efficacy—There was a variable and modest reduction in CT rates for the 8,067 children with minor head trauma whose clinicians received CDS. Adoption —The EHR CT CDS tool was well matched with the organizational mission, values, and priorities of the implementation sites. Implementation— The most important predisposing factors for successful implementation were the presence of an approachable clinical champion at each site and belief that the tool was a relevant, reusable knowledge asset. Enabling factors included an effective integration within the clinical workflow, organizational investment in user training, and ease of use. Maintenance — Reinforcing factors for the EHR CT CDS tool included a close fit with the institutional culture, belief that it was useful for providers and families, and a good educational and informational tool. As such, the EHR CT CDS tool was maintained in clinical practice long after study completion. Conclusion Data from this mixed-methods study complement findings from the efficacy trial and provide critical components for consideration prior to integration and subsequent dissemination of the EHR CT CDS tool. Trial Registration NCT01453621, Registered September 27, 2011
Incapacitating Criminal Corporations

If there is any consensus in the fractious debates over corporate punishment, it is this: a corporation cannot be imprisoned, incarcerated, jailed, or otherwise locked up. Whatever fiction the criminal law entertains about corporate personhood, having an actual “body to kick” — and, by extension, a body to throw into prison — is not one of them. The ambition of this project is not to reject this obvious point, but rather to challenge the less-obvious claim it has come to represent: incapacitation, despite long being a textbook justification for punishing individuals, does not bear on the criminal law of corporations. In this Article, I argue that incapacitation both can and should serve as a justification for punishing criminal corporations. Descriptively, I interrogate how rote appeals to the impossibility of corporate imprisonment obscure more pressing, challenging questions about whether and to what extent the criminal law can vindicate an account of incapacitation that extends to corporate persons. Excavating a richer conceptual framework for incapacitation from our practices of individual punishment, I demonstrate that sanctions we already impose in or just outside the criminal law can be better understood as efforts to incapacitate, rather than to deter or rehabilitate, a criminal corporation. Indeed, reevaluating our understanding of penal incapacitation provides reason to think that we have similar and perhaps stronger reasons for incapacitating corporate persons than we do individuals. Prescriptively, I leverage this comparative framework to argue that incapacitation should be recognized as a core justification for corporate punishment. Although rehabilitation has gained traction in past decades as a basis for punishing corporations, incapacitation stands as a more realistic, more administrable, alternative. This is because a principle of rehabilitation has led to a practice of imposing on corporations intricately designed, but dubiously effective, compliance and internal governance reforms. Incapacitation, by contrast, lends itself to clear, discrete prohibitions for which the criminal law is better situated to justify, impose, and monitor.
Winners and Losers of Marketplace Lending: Evidence from Borrower Credit Dynamics

Using comprehensive credit bureau data, we document that consumers who borrow from marketplace lending (MPL) platforms have lower credit scores and higher default rates in the long run relative to observably similar applicants for bank loans. This underperformance of MPL borrowers is more pronounced when the MPL platforms provide less information to MPL investors, when MPL borrowers are benchmarked against relationship bank borrowers, and for one-time MPL borrowers than repeat MPL borrowers. Overall, our results suggest that MPL lenders face greater information asymmetries with respect to their borrowers than traditional banks.
Saturday, August 21, 2010—Chicago, IL

On Saturday morning at approximately 10:00 a.m. Mona and Delta had traversed the Dan Ryan expressway in Mona’s little Geo and eventually merged into city traffic. By 10:30 they had wrangled their way through the city traffic and arrived at Caleb Barthes’ apartment in Old Town.
The Creation of Stable Dynastic Empires in East and Southeast Asia

The Qin Empire united China but soon fell, being replaced by the Han Empire, which lasted over 400 years to become China’s longest-lived dynasty. Han consolidated Chinese governmental strategy, uniting Ru (Confucian) and Legalist ideas, with some Daoist influence. The Xiongnu Empire rose as a competitor and was largely defeated, but at enormous cost. This set a pattern for later wars on the northern Central Asian frontiers. Meanwhile, Vietnam, Korea, and Japan moved toward civilization, but were still isolated, small powers. This took place in a time of warm, moist climate, which greatly helped both China and the Xiongnu, but did not deeply affect the other regions. The Roman Empire was also benefited; Han and Rome had enough distant and indirect contact to give the Romans some idea of the “silk people” (the Chinese).
Acculturation strategy and innovation in higher education: a study of individuals and dyads

This novel quasi-experimental study examines the relation between two salient constructs: acculturation strategy and innovation in higher education. A sample of 54 undergraduates, comprising equal numbers of assimilated and bicultural students, participated in the first study session where they individually assembled comic books and stationery into new product prototypes to cheer stressed classmates. In the second study session, the students were randomly grouped into 13 homogeneous and 13 heterogeneous acculturated pairs to assemble the comic books and stationery into novel prototypes to help classmates reconcile over a disagreement. Two external innovation judges blindly scored the degree of innovation of each prototype. Findings exhibit that acculturation strategy significantly predicts the original dimension of individual innovation, but dyad acculturation type does not significantly predict dyad level innovation. The study suggests that pairing may not need to be solely based on acculturation strategy for enhancing pair innovation in higher education and organisations.
Single-Site Laparoscopy: Expediting the Learning Curve

Video Objective The objective of this video is to understand the advantages and disadvantages of single site versus multiport laparoscopy and identify the key steps to simplify the single site approach. Setting Academic medical center. Interventions Multiple studies have evaluated single-site versus traditional laparoscopy. While there are no differences in conversion rate, estimated blood loss, postoperative pain and length of hospital stay; it has been shown that single site laparoscopy has an increased operating time but is the preferred cosmetic approach. Using the same basic principles of laparoscopy and implementing them into single site laparoscopy, the surgery dynamics can be simplified and expedite the learning curve. This video will demonstrate these techniques of triangulation, visualization, traction-countertraction and purposeful movements. By visualizing this skillset directly, it will be easier to implement the key steps of single site laparoscopy when put into practice. Conclusion Executing this knowledge of simplification and fundamentals, surgeons will be able to avoid the frustrations of single-site laparoscopy so that these skills may be applied to better serve our patients.
Biomedical Evidence Generation Engine.

With the rapid development of precision medicine, a large amount of health data (such as electronic health records, gene sequencing, medical images, etc.) has been produced. It encourages more and more interest in data-driven insight discovery from these data. It is a reasonable way to verify the derived insights in biomedical literature. However, manual verification is inefficient and not scalable. Therefore, an intelligent technique is necessary to solve this problem. In this paper, we propose a task of biomedical evidence generation, which is very novel and different from existing NLP tasks. Furthermore, we developed a biomedical evidence generation engine for this task with the pipeline of three components which are a literature retrieval module, a skeleton information identification module, and a text summarization module.
Comparison of Conditioning Regimens for Allogeneic Hematopoietic Cell Transplantation in Non-Hodgkin Lymphoma

Background Allogeneic hematopoietic cell transplantation (allo-HCT) allows for the possibility of cure in patients (pts) with Non-Hodgkin Lymphoma (NHL) as it provides an immunologic graft-versus-lymphoma effect. Non-relapse mortality (NRM) was prohibitive in myeloablative regimens, but technical advances with the advent of reduced-intensity conditioning (RIC) or nonmyeloablative (NMA) regimens have decreased these rates. RIC regimens are generally associated with more toxicity and higher NRM than NMA regimens. Though studies showed both approaches are safe and effective, there is lack of direct comparison between these different intensities in NHL. Methods This retrospective study identified pts aged ≥ 18 years who underwent allo-HCT for relapsed/refractory NHL between 3/2008-6/2017 at our center. Outcomes were compared between pts who received NMA and RIC conditioning, with intensity defined per CIBMTR. Progression-free survival (PFS) was the primary outcome. Secondary outcomes included overall survival (OS) and non-relapse mortality (NRM). Additional outcomes included rates of acute GVHD at Day 100, chronic GVHD, and CMV reactivation at Day 100. Regimen intensity and other variables significant by univariate analysis were included in the multivariate analysis Results For the 144 pts identified, median age was 56 years (range, 19-79). More pts received NMA regimens (n=80, 56%) and most did not undergo prior autologous HCT (n=103, 72%). NMA regimens were given more frequently to pts with indolent B-cell lymphoma and were more likely to receive ATG and/or rituximab (p = 0.008, p Conclusion Our study suggests that there are comparable and favorable outcomes between RIC and NMA regimens in allo-HCT for NHL with careful patient and regimen selection. Further studies are needed to better define criteria in choosing between NMA and RIC allo-HCT regimens for pts with NHL.
Radioactive Decay of Cs 137

The spins of the ground states of ${\mathrm{Cs}}^{137}$ and ${\mathrm{Ba}}^{137}$ are known to be 7/2 and 3/2, respectively. The shape of the 518-kev beta-ray spectrum has been measured and found to correspond to the correction factor ${G}^{\ensuremath{'}}={({W}_{0}\ensuremath{-}W)}^{2}+A({W}^{2}\ensuremath{-}1)$ in agreement with previous work. This is the shape predicted by the Fermi theory of beta-ray decay and the Gamow-Teller selection rules for a transition for which $\ensuremath{\Delta}I=\ifmmode\pm\else\textpm\fi{}2$ and there is a parity change. The internal conversion coefficient of the 663-kev gamma-ray has been measured and found to be 0.097, which is in agreement with the theoretical value for magnetic ${2}^{4}$-pole radiation.
Hotel Surfing in California: Which Brand Rides the Best Waves?

This case features R.D. Olson Development (RDOD), a prominent hotel developer that has been presented with an RFP opportunity to develop a hotel in a prime master planned development in Southern California. As RDOD works towards submitting its RFP bid, it has many things to consider, including most notably the brand that it will select for its proposal. With a quality franchisor in place, it must decide whether to pursue a high-quality select-service hotel, or a full-service hotel instead. RDOD’s decision must take into account a number of variables, including and especially the interests of the other project stakeholders. The case follows the typical timeline and process for a development opportunity, specifically focusing on the feasibility work, brand selection, and strategic decision-making as RDOD prepares for its RFP response to the landowner.
Impact of L-glutamine as replacement of dietary antibiotics during post weaning and transport recovery on carcass and meat quality attributes in pigs

Abstract Dietary L -glutamine could be used as an antibiotic alternative to alleviate post-weaning and transport stress. However, the impact of supplementing L-glutamine to newly weaned and transported pigs on final carcass and meat quality characteristics is currently unknown. Therefore, the objective of this study was to evaluate the impact of 0.2% dietary L -glutamine supplementation during post-weaning and transport recovery on carcass and meat quality attributes in pigs. A total of 480 mixed-sex pigs were studied in two production seasons, July-January and April-September (from weaning to harvest), where pigs were randomly assigned to 3 different diets (Non: no antibiotic, Anti: 441 ppm chlortetracycline and 38.6 ppm tiamulin, Gln: 0.20% L -glutamine with no antibiotics) for 14 days after weaning and transport, and then all pigs were fed a basal diet until reaching market weight. Pairs of longissimus dorsi (LD) and psoas major (PM) muscles were obtained from 1 d and 7 d postmortem carcass sides (n = 10 gilts/dietary treatment/season replicate). Overall, no negative impacts of Gln were observed in carcass characteristics including loin eye area, back fat, and muscling score. Dietary Gln did not affect chemical and physical attributes of porcine muscles including pH, protein and lipid content, SF, and WHC (P > 0.05). The Gln treated pigs had decreased CIE L* and hue, suggesting enhanced color stability. April-September replicates had a faster pH decline, paler surface color, higher intra-muscular fat deposition, improved tenderness and water-holding capacity as indicated by lower shear force values, thaw-purge loss, and cooking loss compared to their July-January counterparts (P L -glutamine supplementation as a nutraceutical mitigation strategy could have equivalent impacts on fat and lean accretion, SF, and WHC and some positive impacts on meat color attributes compared to meat from pigs treated with antibiotics.
A guided approach for subtomogram averaging of challenging macromolecular assemblies.

Cryo-electron tomography is a powerful biophysical technique enabling three-dimensional visualization of complex biological systems. Macromolecular targets of interest identified within cryo-tomograms can be computationally extracted, aligned, and averaged to produce a better-resolved structure through a process called subtomogram averaging (STA). However, accurate alignment of macromolecular machines that exhibit extreme structural heterogeneity and conformational flexibility remains a significant challenge with conventional STA approaches. To expand the applicability of STA to a broader range of pleomorphic complexes, we developed a user-guided, focused refinement approach that can be incorporated into the standard STA workflow to facilitate the robust alignment of particularly challenging samples. We demonstrate that it is possible to align visually recognizable portions of multi-subunit complexes by providing a priori information regarding their relative orientations within cryo-tomograms, and describe how this strategy was applied to successfully elucidate the first three-dimensional structure of the dynein-dynactin motor protein complex bound to microtubules. Our approach expands the application of STA for solving a more diverse range of heterogeneous biological structures, and establishes a conceptual framework for the development of automated strategies to deconvolve the complexity of crowded cellular environments and improve in situ structure determination technologies.
Acoustic ranging in meadow katydids: female preference for attenuated calls

For many insects advertisement calls made by males are the primary method of mate choice. Females often have a preference for higher amplitude calls. However, if a male is capable of making a loude...
Why Disability Studies in Criminal Law and Procedure

In recent years, police violence against disabled people has been a source of increased public attention and alarm. By some accounts, anywhere from twenty percent to over half of the people killed each year by law enforcement have at least one disability. Disabled people comprise a high proportion of incarcerated people, making up at least thirty percent of state prisoners and forty percent of detainees in jails. Yet, despite these vulnerabilities to criminalization, police violence, and incarceration, in-depth discussions on disability are relatively limited in law school courses on criminal law and criminal procedure. In this essay, I offer some ideas for how law professors can incorporate critical discussions of disability into their substantive criminal law and criminal procedure courses. Drawing from insights from Disability Studies and Critical Disability Theory, I show how law professors seeking to equip their students with tools for examining the limits of legal protections and provide students with a broader scope of the harms of the criminal legal system can incorporate disability as a lens for legal analysis.
Understanding the industry/state interface in creative industries studies:

It is time to transcend the cultural studies vs. media industries debate in media industries studies. To take advantage of the exemplary focus on real-world behavior of media industries that Stuart...
Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness

The diacylglycerol kinases (DGKs) are a family of enzymes responsible for the conversion of diacylglycerol (DAG) to phosphatidic acid (PA). In addition to their primary function in lipid metabolism, DGKs have recently been identified as potential therapeutic targets in multiple cancers, including glioblastoma (GBM) and melanoma. Aside from its tumorigenic properties, DGKα is also a known promoter of T-cell anergy, supporting a role as a recently-recognized T cell checkpoint. In fact, the only significant phenotype previously observed in Dgka knockout (KO) mice is the enhancement of T-cell activity. Herein we reveal a novel, macrophage-specific, immune-regulatory function of DGKα. In bone marrow-derived macrophages (BMDMs) cultured from wild-type (WT) and KO mice, we observed increased responsiveness of KO macrophages to diverse stimuli that yield different phenotypes, including LPS, IL-4, and the chemoattractant MCP-1. Knockdown (KD) of Dgka in a murine macrophage cell line resulted in similar increased responsiveness. Demonstrating in vivo relevance, we observed significantly smaller wounds in Dgka-/- mice with full-thickness cutaneous burns, a complex wound healing process in which macrophages play a key role. The burned area also demonstrated increased numbers of macrophages. In a cortical stab wound model, Dgka-/- brains show increased Iba1+ cell numbers at the needle track versus that in WT brains. Taken together, these findings identify a novel immune-regulatory checkpoint function of DGKα in macrophages with potential implications for wound healing, cancer therapy, and other settings.
Perspectives on social computing

Social computing has emerged as a broad area of research in HCI and CSCW, encompassing systems that mediate social information across collectivities such as teams, communities, organizations, cohorts, populations, and markets. Such systems are likely to support and make visible social attributes such as identity, reputation, trust, accountability, presence, social roles, expertise, knowledge, and ownership. Social computing is transforming organizations and societies by creating a pervasive technical infrastructure that includes people, organizations, their relationships and activities as fundamental system components, enabling identity, behavior, social relationships, and experience to be used as resources. In this talk, I argue for a broad definition of social computing, selectively review emerging applications, and discuss current research within and beyond IBM that is driving and is driven by the emerging vision of social computing.
Institutional Issues in the Enforcement of Future U.S. Greenhouse Gas Legislation

Future U.S. legislation to curb the emission of greenhouse gases (GHGs) seems likely to include enforcement provisions and to give the U.S. Environmental Protection Agency (EPA) and individual U.S. states significant roles in enforcing its provisions. Following an overview of U.S. environmental enforcement approaches and authorities, this paper considers the history and current state of EPA’s organizational structure for enforcement. It assays the Agency’s working relations with the U.S. Department of Justice (DOJ) and its dealings with state environmental agency enforcement programs. The paper also considers the nature and sources of resource shortfalls that have long impaired the effectiveness of EPA’s enforcement work. It advances specific suggestions to redress the problems it identifies.
Self-Stabilizing Leader Election in Optimal Space

A silent self-stabilizing asynchronous distributed algorithm, SSLE, for the leader election problem, in a connected unoriented network with unique IDs, is given. SSLE uses O (logn ) space per process and stabilizes in O (n ) rounds, where n is the number of processes in the network.
System design and verification process for LHC programmable trigger electronics

The rapid evolution of electronics has made it essential to design systems in a technology-independent form that will permit their realization in any future technology. This article describes two practical projects that have been developed for fast, programmable, scalable, modular electronics for the first-level trigger of Large Hadron Collider (LHC) experiments at CERN, Geneva. In both projects, one for the front-end electronics and the second for executing first-level trigger algorithms, the whole system requirements were constrained to two types of replicated components. The overall problem is described, the 3D-Flow design is introduced as a novel solution, and current solutions to the problem are described and compared with the 3D-Flow solution. The design/verification methodology proposed allows the user's real-time system algorithm to be verified down to the gate-level simulation on a technology-independent platform, thus yielding the design for a system that can be implemented with any technology at any time.
Mother‐Infant Neonatal Separation: Some Delayed Consequences

An earlier study of mothers of premature and full-term infants showed that the type and amount of social interaction between a human mother and her infant in the immediate postpartum period can influence the mother's subsequent behaviour and attitude towards the infant. Separation of a mother from her infant for as short a time as three weeks in the immediate postpartum period can lead to lowered feelings of maternal competency and decreased amounts of attachment behaviour, sometimes continuing for as long as one month after the pair have been reunited. Follow-up of these mothers and infants at 11, 12 and 15 months after discharge from the hospital showed that the effects of separation on maternal attitude and behaviour had disappeared, except that non-separated mothers continued to touch their infants more than separated mothers. Differences in maternal behaviour varied with birth order and sex of the infant and social class membership of the family. These findings are discussed in terms of ethological and social learning theories as they apply to matenal 'social attachment' in the neonatal period. The importance of considering the consequences of neonatal separation for the entire family rather than mother alone is emphasized.
Fuzzy Representation of Pavement Condition for Efficient Pavement Management

This article describes how many government agencies and private consulting companies manage large pavement networks in terms of infrastructure condition assessment and maintenance planning. Efficient pavement management is supported by pavement management systems (PMSs), which includes models for pavement condition assessments considered "valuable" by agency's engineers. This article defines a pavement condition model that is able to overcome surveyors' subjectivity in rating distresses and thereby providing meaningful pavement conditions for the agencies to employ in project planning. The article proposes a fuzzy inference model for calculating pavement condition ratio (PCR) that is specifically tailored to the Alabama Department of Transportation Pavement (ALDOT) guidelines and policies. Applied to several surveyors' ratings, the proposed model has the ability to smooth distress extent differences among surveyors producing PCR values within acceptable range of variability. The approach proposed in this article has the intention of not only enhancing pavement condition characterization but also to exploit the opportunity made available by automation in the collection and interpretation of pavement data which are characterized by an inherent subjectivity.
Case of Occipital Epilepsia Partialis Continua Presenting as Status Migrainosus: Clinical, EEG and Brain MRI Findings (P4.253)

OBJECTIVE: Case report of status migrainosus as the presenting symptom in a patient with occipital epilepsia partialis continua (EPC); including a focused discussion on transient brain MRI findings seen in EPC and its mechanism for pathogenesis. BACKGROUND: EPC and status epilepticus (SE) have been shown to cause transient MRI changes which often correlate with the epileptic focus. DESIGN/METHODS: This is a case report of a 42-year-old woman with acquired left occipital simple and complex partial epilepsy following eclampsia in 2000. Her seizures were characterized by auras of flashing lights and scintillating scotomas lateralizing to her right visual field. In April 2013, she was admitted for a 2-week history of status migrainosus. She reported visual auras recurring every 5-10 minutes accompanied by near constant throbbing headache, nausea and repeated vomiting. Her seizures continued despite rapid escalation of outpatient antiepileptic medications. RESULTS: Extended video-EEG findings performed upon admission demonstrated: 1) frequent local spike or sharp and slow wave discharges localizing to the left occipital or left occipital-posterior temporal region 2) recurring focal electrographic seizures emanating from the left occipital or left occipital-posterior temporal region and 3) patient reported visual auras consisting of flashing lights which correlated with prolonged focal left occipital electrographic seizures. MRI imaging of the brain demonstrated cortically based gyriform T2 FLAIR hyperintensity causing cortical thickening, with involvement of left parietal, temporal, and occipital lobes. Injection of contrast demonstrated subtle asymmetric enhancement of the overlying dura. CONCLUSIONS: The medical literature on transient, often localizing, findings seen on brain MRI in EPC and SE will be reviewed. Proposed mechanisms that lead to these MRI changes include alterations in the blood-brain barrier, cerebral metabolism, and cerebral blood flow. Understanding these mechanisms can facilitate our understanding of epileptogenesis and has the potential for targeted therapies. Study Supported by: Not applicable. Disclosure: Dr. Dai has nothing to disclose. Dr. Grigg-Damberger has received personal compensation in an editorial capacity for Sleep Medicine Clinics.
Computational modeling of complexes of penta-ammine osmium (II) with aromatic ligands

Complexation of aromatic species with penta-ammine osmlium (II)[Os]has remarkable effects on their structure and reactivity. The η2-complexed dearomatized ligand can be encouraged to react in ways of great convenience in synthetic projects. We model the structure of complexes of [Os] with various descriptions of correlation and in various bases. The most satisfactory method for structures is a perturbation correlation corrected model (MP2) with a hybrid basis, 6-31G* on all but osmium, and the LANL2DZ basis and associated pseudopotential for that heavy atom. A B3LYP/hybrid scheme seems to produce better estimates of binding and isomerization energies for a range of ligands, including hydrocarbons, heteroaromatics, and substituted benzenes. © 2003 Wiley Periodicals, Inc. Int J Quantum Chem, 2003
Reversible Electrowetting on Dual-Scale-Patterned Corrugated Microstructured Surfaces

The ability to reversibly switch between a hydrophobic Cassie state and a hydrophilic Wenzel state is often not possible on textured surfaces because of energy barriers which result from the geometry of the microstructure. In this paper, we report on a simple microstructure geometry that allows an aqueous droplet to be reversibly switched between these states by the application of electrowetting. We demonstrate reversible electrowetting in air on microstructured surfaces consisting of parallel corrugations and show that this geometry can be engineered to produce a Cassie state and can be electrically controlled to switch to a Wenzel wetting state having high adhesion. When the electric field was removed, we observed spontaneous dewetting along the corrugations as the droplet transitioned from the Wenzel state back to a Cassie state.
Automated pre-column derivatization of amino acids with o-phthalaldehyde by a reagent sandwiching technique.

Abstract A totally automated method for the pre-column derivatization and analysis of the o -phthalaldehyde amino acids has been described. The derivatives are formed by combining the sample and reagent in a mixer in-line with the column and taking the mixture directly to the column after a precisely controlled reaction time. Reagent addition is by the use of a multi-port automated valve. Over-all precision of the method at the 50–100 pmol level is about 1%. The proposed method has several advantages over previously reported automated methods for this analysis: (a) The reaction time is precisely controlled and can be varied reproducibly if needed by altering the initial mobile phase flow-rate. (b) The use of the auto-sampler only for taking the sample should give better reproducibility than when used for taking sample and reagent. The full-loop mode of sampling can be used to improve sampling precision. (c) The auto-sampler trays are used for samples only, not for mixing vials and/or reagent vials. As many as 48 samples per day can potentially be analyzed. (d) There is no BASIC program needed to control the sampling, mixing, and injection of the samples. (e) Only the actual volume of sample analyzed is injected, undiluted with reagent and/or quenching solution. (f) The method is easier and less expensive to implement than systems employing robotics, although it is more expensive than procedures which use the auto-sampler for taking the sample and reagent due to the cost of the automated valve for reagent addition. (g) The derivatives are formed on-line and are not exposed to air or light. Whether this enhances the stability of the derivatives is open to speculation.
Amenable subgroups of semi-simple groups and proximal flows

We present a classification of maximal amenable subgroups of a semi-simple groupG. The result is that modulo a technical connectivity condition, there are precisely 2′ conjugacy classes of such subgroups ofG and we shall describe them explicitly. Herel is the split rank of the groupG. These groups are the isotropy groups of the action ofG on the Satake-Furstenberg compactification of the associated symmetric space and our results give necessary and sufficient conditions for a subgroup to have a fixed point in this compactification. We also study the action ofG on the set of all measures on its maximal boundary. One consequence of this is a proof that the algebraic hull of an amenable subgroup of a linear group is amenable.
A Rigorous Method for Synthesis of Offset Shaped Reflector Antennas

In this paper the problem of synthesis of offset shaped single reflector antenna is considered. This problem has to be solved when a reflector antenna system is required to control the field amplitude and/or phase on the far-field or on the output aperture in the near-field. Achieving high efficiency is a very important objective of the design and shaped reflector antennas are used for that purpose.The equations of the problem are strongly nonlinear partial differential equations which can not be analyzed by standard techniques. Though the problem has been the subject of study by many authors for over 40 years, up until recently, there were no rigorous theoretical results resolving completely the questions of existence and uniqueness. With few exceptions, authors have attacked the problem with heuristic numerical procedures, and, depending on the specific formulation, obtained different results not always in agreement with each other.In this paper a new method for solving the single reflector problem is presented. The new method allows a complete and mathematically rigorous investigation of this problem. Furthermore, the proposed method lends itself to a numerical implementation and we present here several examples.
Biodiversity in Hudson River shore zones: influence of shoreline type and physical structure

The shore zones of the Hudson River, like those of many developed waterways, are highly varied, containing a mix of seminatural and highly engineered shores. Our goal was to document the biodiversity supported by different kinds of shore zones in the Hudson. We chose six common types of shore zones, three of them “natural” (sand, unconsolidated rock, and bedrock), and three of them engineered (riprap, cribbing, and bulkheads). We measured selected physical characteristics (shore zone width, exposure, substrate roughness and grain size, shoreline complexity) of three examples of each of these shore types, and also sampled communities of terrestrial plants, fishes, and aquatic and terrestrial invertebrates. Community composition of most taxa differed across shore types, and frequently differed between wide, sheltered shores and narrow, exposed shores. Alien plant species were especially well represented along engineered shores. Nevertheless, a great deal of variation in biological communities was not explained by our six-class categorization of shore zones or the physical variables that we measured. No single shore type supported the highest values of all kinds of biodiversity, but engineered shore zones (especially cribbing and bulkheads) tended to have less desirable biodiversity characteristics than “natural” shore zones.