cssi/SciSciGPT-SciSciNet huggingface dataset:
Cultural Adaptation Resources for Nutrition and Health in New Immigrants in Central North Carolina

This paper presents results of a study that was conducted for the purposes of describing available human services resources relating to nutrition, physical health, and behavioral health for new and recent immigrants (predominantly Mexican immigrants, but groups from Southeast Asia and continental Africa as well) in Guilford County, NC. Sixty-five service providers were determined to represent cultural adaptation resources providing either direct and/or ancillary assistance to limited English proficient immigrants. Seventeen direct assistance providers specialized in food and nutrition programs, but only 2 had targeted programs for addressing food scarcity, insecurity, and nutritional deficiencies in immigrant households. Four of 15 direct physical health services providers had clinical care or specialty programs for immigrants. Finally, 5 of 16 direct behavioral health care providers offered mental health treatment and counseling services adapted specifically for targeted immigrant groups. These findings highlight the limited development of the existing human services network to increase its capacity to provide nutrition and health related services to a growing community of diverse immigrant groups. These descriptive results underscore a need for additional local level or community based resources to be directed towards increasing the community’s ability to provide essential human services to population groups not yet language proficient and acculturated to “American community standards.”
Harnessing Web 2.0 for ERP Implementations

ERP implementations cost billions of dollars annually in United States alone. This article describes how Web 2.0 may be used to reduce the cost, improve the quality and lower the risk of ERP implementations. Challenges and requirements for a web 2.0 knowledge repository system are gathered from ERP implementation communities through a case study. To fulfill these requirements, the article presents EPICS, a web 2.0 system that supports knowledge reuse in ERP implementations. A prototype is built upon a number of popular open source software packages. Prototype deployment at a real-world ERP community shows promising results. Besides cost savings, interesting business models emerge as a result of the deployment.
The WARMAP system closed-loop simulate validation based on RTDS

The Wide-Area Monitoring Analysis Protection Control System (WARMAP) is used for security and stability analysis and anti-accident measure in system development process in large-scale AC/DC parallel power grid. However, the WARMAP system should collect the required data from the Energy Management System (EMS) for calculation that not only increased the flexibility of the system but also extend the system development cycle. RTDS has wide application prospects in operation analysis, online stability analysis and decision of large-scale AC/DC parallel grid, because of parallel computing ability and expansibility. In RTDS an accurate model can be built, simulation data that is close to actual status of the power network operation can be obtained. By digital communication, the data from simulation is uploading to WARMAP system for Analysis and calculation, so that ensures the data accurateness and increases the portability, at the same time system development cycle is reduced
Interspecies comparison of liver carcinogenesis: implications for cancer risk assessment

The morphology of hepatocellular carcinoma is similar among mice, rats and humans, and the cellular pathogenesis shows features that are both similar and divergent among these species. However, major elements of etiology, molecular pathogenesis, and natural history differ between humans and rodents. As a reflection of these species-determined differences, rodents appear to be neither highly sensitive nor highly specific surrogates for detecting agents that are potential causes of hepatocellular cancer in humans. Results of tests of chemical carcinogenicity in rodents are likely to include a significant number of both false-positive and false-negative risks for humans.
Molecular Determinants of Species Specificity in the Coronavirus Receptor Aminopeptidase N (CD13): Influence of N-Linked Glycosylation

ABSTRACT Aminopeptidase N (APN), a 150-kDa metalloprotease also called CD13, serves as a receptor for serologically related coronaviruses of humans (human coronavirus 229E [HCoV-229E]), pigs, and cats. These virus-receptor interactions can be highly species specific; for example, the human coronavirus can use human APN (hAPN) but not porcine APN (pAPN) as its cellular receptor, and porcine coronaviruses can use pAPN but not hAPN. Substitution of pAPN amino acids 283 to 290 into hAPN for the corresponding amino acids 288 to 295 introduced an N-glycosylation sequon at amino acids 291 to 293 that blocked HCoV-229E receptor activity of hAPN. Substitution of two amino acids that inserted an N-glycosylation site at amino acid 291 also resulted in a mutant hAPN that lacked receptor activity because it failed to bind HCoV-229E. Single amino acid revertants that removed this sequon at amino acids 291 to 293 but had one or five pAPN amino acid substitution(s) in this region all regained HCoV-229E binding and receptor activities. To determine if other N-linked glycosylation differences between hAPN, feline APN (fAPN), and pAPN account for receptor specificity of pig and cat coronaviruses, a mutant hAPN protein that, like fAPN and pAPN, lacked a glycosylation sequon at 818 to 820 was studied. This sequon is within the region that determines receptor activity for porcine and feline coronaviruses. Mutant hAPN lacking the sequon at amino acids 818 to 820 maintained HCoV-229E receptor activity but did not gain receptor activity for porcine or feline coronaviruses. Thus, certain differences in glycosylation between coronavirus receptors from different species are critical determinants in the species specificity of infection.
Estimating microbial survival parameters from dynamic survival data using Microsoft Excel

Summary Reliable survival parameter estimation is an essential part of building predictive models for microbial survival. It has been demonstrated that these parameters can be accurately identified using a one-step regression approach that fits a survival model to multiple dynamic data sets at once. However, the existing methods are not quite user-friendly because their application requires relatively high computer skills. In this study, a recursive equation for the Weibull model was used to construct microbial survival curves under dynamic conditions. Based on this, a procedure was developed to estimate survival parameters by fitting the equation to dynamic survival data sets using the built-in functions and Solver of Microsoft Excel. The results showed that the method provided an easy and accurate way for estimating microbial survival parameters.
Costs of Financial Distress, Delayed Calls of Convertible Bonds, and the Role of Investment Banks

In a frictionless market with perfect information, a shareholder-wealth- maximizing firm should force conversion of its convertible bond issue into stock as soon as the bond comes in-the-money. Firms however appear to systematically delay forced conversion, sometimes for years, beyond this time. We show that the observed delays can be plausibly explained in terms of costs to shareholders of a failed conversion and the ensuing financial distress. Firms delay the forced conversion to avoid the self-fulfilling outcome that bondholders expect the conversion to fail, tender their bonds for cash, and the stock price falls to account for the costs of financial distress, in which case tendering for cash is in fact optimal. Unlike other explanations of delayed forced conversion, we can explain the common use of investment banks to underwrite these transactions, since the banks can eliminate the self-fulfilling bad outcome.
Utility of an OAI service provider search portal

The Open Archives Initiative (OAI) Protocol for Metadata Harvesting (PMH) facilitates efficient interoperability between digital collections, in particular by enabling service providers to construct, with relatively modest effort, search portals that present aggregated metadata to specific communities. This paper describes the experiences of the University of Illinois at Urbana-Champaign Library as an OAI service provider. We discuss the creation of a search portal to an aggregation of metadata describing cultural heritage resources. We examine several key challenges posed by the aggregated metadata and present preliminary findings of a pilot study of the utility of the portal for a specific community (student teachers). We also comment briefly on the potential for using text analysis tools to uncover themes and relationships within the aggregated metadata.
A UIMA wrapper for the NCBO annotator

Summary: The Unstructured Information Management Architecture (UIMA) framework and web services are emerging as useful tools for integrating biomedical text mining tools. This note describes our work, which wraps the National Center for Biomedical Ontology (NCBO) Annotator—an ontology-based annotation service—to make it available as a component in UIMA workflows. Availability: This wrapper is freely available on the web at http://bionlp-uima.sourceforge.net/ as part of the UIMA tools distribution from the Center for Computational Pharmacology (CCP) at the University of Colorado School of Medicine. It has been implemented in Java for support on Mac OS X, Linux and MS Windows. Contact: chris.roeder@ucdenver.edu
Spherical harmonic inductive detection coils for dynamic pre-emphasis.

The issue of eddy currents induced by the rapid switching of magnetic field gradients is a long-standing problem. A new method for dealing with this problem is presented whereby spatial harmonic components of the magnetic field are continuously sensed, through their temporal rates of change, and corrected. In this way, the effects of the eddy currents on the magnetic field can be detected and correction currents applied to the appropriate gradient or shim coils in a time much less than the rise time of the gradients. This new methodology has the potential to dynamically shape eddy current corrections for multiple spatial harmonic components of the field. Magn Reson Med 60:277–287, 2008. © 2008 Wiley-Liss, Inc.
Roland's Lament: Its Meaning and Function in the Chanson de Roland

FEW critics today will care to question seriously the eminence which the nineteenth and twentieth centuries have granted the Chanson de Roland among the masterpieces of mediaeval literature. No one is likely to read the poem without being profoundly moved by the brief passage in which Roland laments at the sight of his massacred army. The purpose of this essay is to suggest something of the intrinsic quality of that passage and to analyze its relationship to the tone and structure of the first half of the poem. To understand the action in the passage and appreciate the fundamentals of its artistry, we need little more than an awareness of what is in effect common knowledge: before crossing the Pyrenees from Spain into France, Charlemagne has left at Roncevaux a rearguard of twenty thousand men to guard the mountain-pass under the command of his nephew and most trusted vassal, Roland. Despite an attack by a hundred thousand Saracens, Roland has refused to call for help, as his brother in arms, Oliver, would have had him do. Now that only sixty of his men are left alive, he realizes that he must assume the responsibility for the massacre: Rollant reguarded es munz e es lariz. De eels de France i veit tanz morz gesir, E il les pluret cum chevaler gentill: "Seignors barons, de vos ait Deus mercit. Tutes vos anmes otreit il pareYs; En seintes flurs il les facet gesir. Meillors vassals de vos unkes ne vi. Si lungement tuz tens m'avez servit, A oes Carlon si granz paYs cunquis. Li empereres tant mare vos nurrit!
Laser-induced surface damage of transparent dielectrics

Relative values of surface-damage thresholds of transparent dielectrics are calculated for various angles of incidence and polarization. The analysis is valid for damage mechanisms that depend on the electric-field strengths in the immediate vicinity of a damage site. The mechanisms of small inclusions and avalanche breakdown are shown to be included in the range of validity. An example is presented to illustrate how the results can be used in the design of damage-resistant optical components.
Using LiDAR data to map gullies and headwater streams under forest canopy: South Carolina, USA

Abstract The southeastern Piedmont of the USA was severely gullied during the early 20th century. A thick canopy established by reforestation in many areas now inhibits the identification or mapping of gullies by aerial photography or other conventional remote sensing methods. An Airborne Laser-Scanning (ALS or LiDAR) mapping mission flown for the U.S. Forest Service in April, 2004 acquired bare-Earth topographic data. This paper tests the ability of the ALS topographic data to identify headwater channels and gullies for two branching gully systems in forested areas and to extract gully morphologic information. Comparisons are made with field traverses using differential GPS and reference cross sections measured by leveling surveys. At the gully network scale, LiDAR data provide accurate maps – the best available – with robust detection of small gullies except where they are narrow or parallel and closely spaced. Errors in mapping channel location and network topological connectivity under forest canopy increase with attempts to identify smaller features such as large rills. The ability of LiDAR data to map gullies and channels in a forested landscape should improve channel-network maps and topological models. At the gully reach scale, attempts to use LiDAR data to extract gully cross-section morphologic information under forest canopy were less successful due to systematic underestimation of gully depths and overestimation of gully top widths. Limited morphologic accuracy of the data set at this scale may be due to low bare-Earth point densities, shadowing of gully bottoms, and filtering of topographic discontinuities during post-processing. The ALS data used in this study are not suitable for detailed morphometric analysis or subtle change detection to monitor gullies or develop sediment budgets. Data collection may be improved by orienting flights over gullies and with increased point densities through improved scanner technology or better filtering and software capabilities to differentiate between vegetation and ground surfaces.
The utility of a HindIII polymorphism of factor VIII examined by rapid DNA analysis.

Summary. A previously described HindIII restriction fragment length polymorphism (RFLP) of factor VIII (FVIII) has its polymorphic site in the unsequenced nineteenth intron. We have located the polymorphic site, as well as an invariant site, by amplifying and sequencing IVS 19 using the polymerase chain reaction (PCR). The oligonucleotide primers were synthesized from known FVIII sequence on either side of the 19–20 splice junction. The amplified product was cloned into a plasmid and sequenced by the dideoxy chain termination method. The polymorphic HindIII site was 103 bp and the invariant site 184 bp from the 3’end of the nineteenth exon. The frequency of the polymorphism was determined in 457 subjects (643 chromosomes) of seven ethnic groups on whom frequency of the BclI RFLP of IVS 18 was also assessed. The HindIII site is highly polymorphic in all groups, ∼ 0.25:0.7 5, the expected heterozygosity averaging 37.6%. and the observed number of heterozygotes did not differ significantly from expectation. The (+):(-) allelic ratio is similar in all groups, except African-Americans in whom it is reversed. Strong allelic association (linkage disequilibrium) is present between the HindIII polymorphism of IVS 19 and the BclI polymorphism of IVS 18.
Impact of Diabetes on Outcome of Total Ankle Replacement.

Background:As the incidence of diabetes mellitus (DM) grows, managing patients with diabetes and concomitant ankle arthritis poses a challenging clinical dilemma. While diabetes is known to be a ri...
Production of mummichog ( Fundulus heteroclitus ): Response in marshes treated for common reed ( Phragmites australis ) removal

The invasion of U.S. east coast salt marshes by common reed (Phragmites australis) and the efforts to remove it and restore marshes to their natural vegetation (Spartina spp.) can directly impact mummichog (Fundulus heteroclitus) as this abundant species is critically linked to marsh habitat. We estimated population density, growth, and biomass to determine production of mummichog in treated Phragmites (''Treated,'' now dominated by Spartina), untreated Phragmites, and naturally occurring Spartina habitats in Delaware Bay using throw traps for small fish (mean 5 24.1 mm standard length or SL, 95% CI 5 10-38) and tag/recapture for large fish (mean 5 36.5 mm SL, 95% CI 5 18-64). Mean population density of small fish on the marsh surface was significantly higher in the Spartina (20.2 fish m 22 ) and Treated (14.1 fish m 22 ) habitats than in the Phragmites (0 fish m 22 ) habitat. Population density of large fish was similar among all three habitats (mean 5 0.9-1.7 fish m 22 ). Mean absolute growth rates of large fish were significantly higher in the Spartina (0.24 mm d 21 ) and Treated (0.24 mm d 21 ) habitats than in the Phragmites (0.13 mm d 21 ) habitat. Mean monthly mummichog production during June to September varied among habitats with Spartina highest (1.22 g dw m 22 mo 21 ), Treated intermediate (0.51 g dw m 22 mo 21 ), and Phragmites lowest (0.07 g dw m 22 mo 21 ). Small fish were the largest contributor to the production estimates in Spartina and Treated habitats. The Phragmites habitat had little or no standing water at low tide (i.e., optimal habitat for small fish was lacking), and thus, it had the lowest production for mummichog. These results also indicated that Treated marshes were more similar to Spartina than to Phragmites habitat; therefore, it appears that habitat quality and mummichog production can be increased with restoration.
Cell Damage and Cell Renewal in the Lung

A basic principle of wound healing is that cell loss will also trigger cell regeneration involving proliferation. This simple concept is actually quite difficult to study in the context of the complex multicellular environment of the lung. The pattern of the proliferative response is predicated on the cell type that is damaged, the extent and degree of the damage, and whether the insult is acute or chronic. When studying cell renewal, it is critically important to define the type of damage, its extent, and the cell types involved so that the nature of the reparative response can be put into context. Toxicologists have contributed vital information that has helped define lung cell reparative potential.
Model for evaluating avian renal hemodynamics and glomerular filtration rate autoregulation

Multiple vascular connections in normal avian kidneys make it difficult to experimentally manipulate renal blood flow patterns and perfusion pressures. In this study, hemostatic clips were used to obstruct the ureter of one kidney at the level of the ischiadic artery (IA) in anesthetized 3-wk-old chicks (Gallus domesticus). Kidney tissue upstream from the ureteral obstruction degenerated, leaving an intact caudal renal division with one route of arterial inflow branching from the IA. Renal function studies were conducted, using general anesthesia, when the birds reached 12-15 wk of age. A snare placed around the IA was used to unilaterally decrease renal arterial perfusion pressure (RAPP) for the experimental kidney. Under control conditions (snare loose), urine flow rates (UFR), glomerular filtration rates (GFR), clearance of p-aminohippuric acid, and fractional excretion of Na, K, Ca, and PO4 did not differ significantly, per gram of kidney weight, when experimental and intact contralateral kidneys were compared. Gradual tightening of the IA snare reduced RAPP stepwise. UFR decreased significantly from the initial control value when RAPP reached 40 mmHg, and urine flow ceased completely when RAPP reached 30-35 mmHg. In four of five birds, GFR did not decrease significantly between 110 and 60 mmHg but did decrease significantly below 60 mmHg. Urine osmolality was inversely correlated with UFR. Clearance of PAH did not decrease significantly from control values as RAPP ranged from 100 to 37 mmHg, possibly caused by increased renal portal blood flow. Overall, these results provide the first direct demonstration that in domestic fowl GFR is autoregulated at reduced RAPP.
Following the Kentucky General Assembly: With Apologies to Niccolo Machiavelli and the ABC Children's Programming Division

No lawyer's knowledge of Kentucky law is safe while the state legislature is in session. Everything from the rules for the taxation of small businesses to the procedures of juvenile courts is subject to change in this period and it is often important to monitor these developments on behalf of current and future clients. To do so, it is necessary to understand something of Kentucky legislative procedure. This article looks at the Kentucky legislative process, noting the myriad limits on lawmaking imposed by the state constitution. These include rules restricting the length of sessions, mandates setting super-majorities for bills raising or spending state funds, and the requirement that all provisions of a bill be on the same topic. Tools for tracking legislation are also discussed.
LIFETIME MARIJUANA USE IS ASSOCIATED WITH INCREASED RISK OF ABDOMINAL AORTIC-ILIAC CALCIUM AND NOT CORONARY ARTERY CALCIUM BY MIDDLE AGE

The impact of marijuana exposure on cardiovascular disease in long term population based studies is still lacking. We studied the association between cumulative lifetime exposure to marijuana use and development of subclinical atherosclerosis as measured by coronary artery calcium (CAC) and
On the Interpretation of Quantum Coherent Beats Observed in Two-Dimensional Electronic Spectra of Photosynthetic Light Harvesting Complexes

The observation of long-lived electronic quantum coherence in a photosynthetic light harvesting system [Engel et al. Nature2007, 446, 782] has led to much effort being devoted to elucidation of the quantum mechanisms of the photosynthetic excitation energy transfer. In this paper we examine the question of whether the decay of the coherent beating signal is due to quantum mechanical decoherence or ensemble dephasing (also called “fake decoherence”). We compare results based on the quantum master equation description of the time-evolution of the reduced density matrix with a mixed quantum/classical approach where the ensemble average is calculated after the dynamics. The two methods show good agreement with results from the quantum master equation in terms of the decay of quantum coherent oscillations when ensemble average is considered for the mixed quantum/classical approach. However, the results also demonstrate it remains possible that the quantum coherent motion is robust under individual realizations...
Effect of Leucogenenol on Origin of Hemolysin in Normal and Splenectomized Rats

SummaryIt has been found that daily injections of leucogenenol, at the time of and following one injection of sheep erythrocytes, causes a marked increase in the concentration of antibody-forming cells in lymphatic tissues as well as in the spleen and bone marrow. In intact animals this results in earlier formation of maximum titers of hemolysin in the serum and causes splenectomized animals to respond to the injection of sheep erythrocytes with the formation of normal maximum titers.It is suggested that leucogenenol stimulates the formation of antibody-reactive cells from precursors.
Association Between Hypertonic Saline and Hospital Length of Stay in Acute Viral Bronchiolitis: A Reanalysis of 2 Meta-analyses

Importance Two previous meta-analyses of nebulized hypertonic saline (HS) on hospital length of stay (LOS) in acute viral bronchiolitis have suggested benefit. Neither study fully addressed the issue of excessive heterogeneity in the cohort of studies, indicating that it may be inappropriate to combine such dissimilar studies to estimate a common treatment effect. Objective To reanalyze the existing data set for sources of heterogeneity to delineate the population most likely to benefit from HS. Data Sources We used the previously analyzed cohort of randomized trials from 2 published meta-analyses comparing HS with normal saline (or, in 1 case, with standard of care) in infants hospitalized for bronchiolitis. We also repeated the search strategy used by the most recent Cochrane Review in the Medline database through September 2015. Study Selection Eighteen randomized clinical trials of HS in infants with bronchiolitis reporting LOS as an outcome measure were included. Data Extraction and Synthesis The guidelines used for abstracting data included LOS, study year, setting, sample size, type of control, admission/discharge criteria, adjunct medications, treatment frequency, mean day of illness at study enrollment, mean severity of illness scores, and mean age. Main Outcomes and Measures Weighted mean difference in LOS and study heterogeneity as measured by the I 2 statistic. Results There were 18 studies included of 2063 infants (63% male), with a mean age of 4.2 months. The mean LOS was 3.6 days. Two main sources of heterogeneity were identified. First, the effect of HS on LOS was entirely sensitive to the removal of one study population, noted to have a widely divergent definition of the primary outcome. Second, there was a baseline imbalance in mean day of illness at presentation between treatment groups. Controlling for either of these factors resolved the heterogeneity ( I 2 = reduced from 78% to 45% and 0%, respectively) and produced summary estimates in support of the null hypothesis (that HS does not affect LOS). There was a weighted mean difference in LOS of −0.21 days (95% CI, −0.43 to +0.02) for the sensitivity analysis and +0.02 days (95% CI, −0.14 to +0.17) for studies without unbalanced treatment groups on presentation. Conclusions and Relevance Prior analyses were driven by an outlier population and unbalanced treatment groups in positive trials. Once heterogeneity was accounted for, the data did not support the use of HS to decrease LOS in infants hospitalized with bronchiolitis.
HCP-20A CLINICAL CARE PATHWAY TO IMPROVE THE ACUTE CARE OF PATIENTS WITH GLIOMA

BACKGROUND: Patients with glioma are at high risk for tumor and treatment related complications. Few guidelines exist to direct the management of these supportive care needs. Our prior work suggests that a standardized clinical care pathway can improve the care of patients with glioma. METHODS: We designed a quality improvement (QI) project to address the acute care needs of patients with glioma. We formed a multidisciplinary team and selected twenty best practice measures from the literature. Using a plan-do-study-act framework, we brainstormed and implemented various improvement strategies starting in October 2013. Statistical process control charts were used to assess progress. RESULTS: Retrospective data was available for 12 best practice measures. The baseline population consisted of 98 patients with gliomas. Record review suggested wide variation in performance, with compliance ranging from 30% to 100%. The team hypothesized that lack of process standardization may contribute to less-than-ideal performance. After implementing improvement strategies, we reviewed the records of 63 consecutive patients with glioma. The proportion of patients meeting criteria for 12 practice measures improved (65% pre QI-work; 76% post-QI work, p > 0.1), although not statistically significant. Unexpectedly, a higher proportion of patients were readmitted within 30 days of hospital discharge but the proportions for preventable readmissions were similar. Post-operative urinary tract infections (UTIs), venous thromboembolic complications and outpatient falls were identified as opportunities for improvement, with a significant decrease in the incidence of UTIs after interventions were established (p < 0.01). Barriers to pathway development included difficulties with transforming manual measures into electronic data sets. CONCLUSIONS: Creating evidence based clinical care pathways for addressing the acute care needs of patients with glioma is feasible and important. Data dashboards help to inform additional improvement work. There are many challenges, however, to developing sustainable systems for measuring and reporting performance outcomes over time.
Bifurcation features of mixtures containing CO and hydrocarbons in diesel oxidation catalyst

Abstract A model of a monolith reactor with radial gradients in the washcoat is used to study the ignition-extinction of pure CO, C2H6 and C3H6 and of their mixtures on a Pt/Al2O3 diesel oxidation catalyst. The ignition temperature of the individual species oxidation increases upon an increase in feed concentration of either CO or C3H6 and decreases upon an increase in feed concentration of C2H6. This is because CO, C3H6 have negative order kinetics and C2H6 has positive order kinetics. We determine the steady-state hysteresis behavior of conversion versus feed temperature during co-oxidation of CO and hydrocarbons (C3H6, C2H6). A single S-shaped bifurcation diagram of conversion versus inlet temperature is obtained during the co-oxidation of all feed mixtures of CO and C3H6 because the activation energies of CO and C3H6 are close to each other. The presence of CO in the feed inhibits the oxidation of propylene during the co-oxidation of CO and C3H6. In contrast, the ignition temperatures of pure CO and pure C2H6 are much different and CO ignites at a much lower temperature than C2H6. A double-S shaped bifurcation diagram is obtained when hysteresis exists for both CO and C2H6 during the co-oxidation. The oxidation of CO present in the feed increases the catalyst temperature and this reduces the C2H6 ignition temperature. The separated ignition is transformed to a simultaneous ignition when the CO concentration in the feed is sufficiently high. We determine the boundary in the parameter space of feed compositions and other operating conditions that separate the simultaneous and separate ignition. The application of this result for the design of DOCs for treating exhaust gases at lower inlet temperatures is discussed.
Protein Phosphorylation and the Regulation of Sugar Transport in Gram-Negative and Gram-Positive Bacteria

Sugar uptake and cytoplasmic inducer generation appear to be regulated by the phosphenolpyruvate: sugar phosphotransferase system (PTS) by distinct mechanisms in Gram-negative versus Grampositive bacteria. In Gram-negative bacteria, the free form of the glucose-specific IIA protein of the PTS, which can be phosphorylated on a histidyl residue by PEP and the PTS energy coupling proteins, inhibits non-PTS permease activities. In Gram-positive bacteria, the phosphorylated form of the energy coupling HPr protein of the PTS, which can, be phosphorylated on a seryl residue by ATP and a protein kinase, appears to inhibit non-PTS permease activities. In this summary article, the current status of these two PTS-mediated regulatory mechanisms will be evaluated.
Mutually Exclusive Data Dissemination in the Mobile Publish/Subscribe System

The topic-based mobile publish/subscribe (pub/sub) system has shown the potential applications in many scenarios, e.g., product coupon distribution. In this paper, we focus on the budget-constrained data dissemination services with a pre-determinated total amount of copy. A mobile user may subscribe data under different topics, but receiving a copy in any topic is enough. This is the mutually exclusive delivery requirement in many scenarios. In light of the different amounts of data and the different popularity levels of data in each topic, deciding which data should be forwarded to mobile users becomes an important problem. This paper aims to design an efficient data dissemination scheme in the aforementioned scenario, which minimizes the maximum dissemination delay, and incurs small communication overhead at the same time. We start with the offline message dissemination problem, and the corresponding optimal solution is proposed. Later, we consider the online situation, and propose a distributed data forwarding algorithm, which considers both the amount of data in different topics, mobile users' subscription, and their data forwarding abilities, respectively. The real trace driven experiments show that the proposed scheme achieves a good performance.
Quantitative FRET data analysis: protein localization in living specimens

The current advances in fluorescence microscopy coupled with the development of new fluorescent probes and detectors provide the tools to study protein associations in living specimens using FRET microscopy. Upon energy transfer, donor fluorescence is quenched and acceptor fluorescence is increased (sensitized), resulting in a decrease in donor excitation intensity or lifetime. The fluorophore molecule used for FRET imaging has a characteristic absorption and emission spectrum that should be considered for characterizing the FRET signal acquired using one- and two-photon excitation FRET microscopy. There are a number of methods to avoid, minimize or correct the spectral bleedthrough (SBT) contamination in intensity-based FRET, each having specific limitations depending on the level of sensitivity desired. We have developed an algorithm to correct the contamination in the FRET image to estimate the energy transfer efficiency (E%) and the distance (r) between donor and acceptor molecule. In this presentation we explain the influence of back-bleedthrough signal in quenched donor channel, acceptor excitation wavelength exciting donor component of the double labeled specimen (we call them additional SBT in this paper) and its influence in the calculation of energy transfer efficiency and the distance between donor and acceptor molecules. Considerable amount of additional SBT signals were observed in the intensity based multiphoton FRET microscopy compared to the one-photon FRET microscopy.
Abstract 196: Involvement of Peroxynitrite Formation in Angiotensin II Induced Changes in Na+K+ATPase Activity in HK2 Cells

Angiotensin II (AngII) induces both superoxide (O2-) and nitric oxide (NO) generation forming peroxynitrite (ONOO-) in biological systems. To determine the role of ONOO- in AngII induced sodium excretory responses, we examined Na+K+ATPase (NKA) activity in cultured HK2 cells (human kidney proximal tubule cell line) incubated for 30 min with a wide range (10 pM to 200 μM) of AngII concentrations (conc) in the presence or absence of a ONOO- scavenger, mercapto-ethyl-guanadine (MEG; 200μM). Post incubation HK2 cellular membrane fractions were used for measurement of NKA activity via colorimetric assay capable of detecting inorganic phosphate (Pi). Baseline value of NKA activity in these HK2 cells was measured as 10.3 ±0.7 μmoles of Pi liberated/mg protein/hr (n=12). AngII exerts dose-dependent differential effects on NKA activity. Compared to the baseline value, NKA activity was increased at lower conc (13.7±1.3% at 10 pM to 19.6±1.5% at 100nM) and decreased at higher conc (-6.0±0.8% at 1 μM to -38±2.1% at 200 μM ) without any significant effect at 500 nM conc (-1.2±0.6%) of AngII. Interestingly, MEG treatment markedly attenuated these AngII induced changes in NKA activity, both at lower conc (activity increased only to 7.8±0.67% at 10 pM and to 8.9±0.57% at 100nM; an average reduction of 33.2±2.4% in stimulatory effects) and at higher conc (activity decreased to -3.0±0.7% at 1 μM and to -20±0.57% at 200 μM; an average reduction of 54.4±4.1% in inhibitory effects). Co-incubation with O2- scavenger, tempol (1 mM) or NO synthase inhibitor, nitro-L-arginine methyl ester (100 μM) did not alter these AngII induced responses in HK2 cells indicating that neither O2- , nor NO, was directly involved in mediating these responses. AT1 receptor (AT1R) blocker, losartan (10μM) treatment prevented these AngII induced changes on NKA activity confirming the involvement of AT1R signaling in these responses. These findings demonstrate a direct contributory role for concomitant ONOO- generation in mediating AngII induced changes in NKA activity in the proximal tubular cells. These data also suggest a reno-protective role for ONOO- in minimizing sodium retaining action of AngII by the renal tubules, particularly in the conditions associated with enhanced renin-angiotensin system.
Trait Predictors of Relational Control

This study attempted to identify clusters of traits which best predicted the use of relational control style. After 125 subjects interacted in different settings, their interaction was coded using ...
Effect of sedation on quantitative electroencephalography after cardiac arrest

Abstract Background Electroencephalography (EEG) has clinical and prognostic importance after cardiac arrest (CA). Recently, interest in quantitative EEG (qEEG) analysis has grown. The qualitative effects of sedation on EEG are well known, but potentially confounding effects of sedatives on qEEG after anoxic injury are poorly characterized. We hypothesize that sedation increases suppression ratio (SR) and decreases alpha/delta ratio (ADR) and amplitude-integrated EEG (aEEG), and that the magnitude of sedation effects will be associated with outcome. Methods We routinely monitor comatose post-arrest patients with EEG for 48–72 h. We included comatose EEG-monitored patients after CA who had protocolized daily sedation interruptions. We used Persyst v12 to quantify qEEG parameters and calculated medians for 10 min immediately prior to sedation interruption and for the last 5 min of interruption. We used paired t-tests to determine whether qEEG parameters changed with sedation cessation, and logistic regression to determine whether these changes predicted functional recovery or survival at discharge. Results 78 subjects were included (median age 56, 65% male). Interruptions occurred a median duration of 34 h post-arrest and lasted a median duration of 60 min. Prior to interruption, higher aEEG predicted survival, while lower SR predicted both survival and favorable outcome. During interruption, SR decreased (p Conclusion Higher aEEG and lower SR predict survival after CA. Sedation alters aEEG and SR, but importantly does not appear to affect the relationship between these parameter values and outcome.
Considerations of constructing quality, health and safety management system for agricultural products sold via e-commerce

The continual development of internet technology and its extensive applications in the business domain have enabled the development of e-commerce in relation to agricultural products. However, this development is facing some “pain points.” While middle-class consumers are displaying ever-increasing demand for high-quality agricultural products via the e-commerce environment, the quality and safety of agricultural products under this environment cannot be guaranteed. Therefore, to strengthen the evaluation of the technical level of agricultural products quality, health and safety supervision via e-commerce, understand the problems in the regulatory techniques of e-commerce of agricultural products in China, increase the agricultural product quality, health and safety supervision via e-commerce are of great importance to satisfy the growing consumer demand for e-commerce in agricultural products. Based on the comparative analysis of the evaluation methods and the establishment methods of evaluation index system, this research innovatively established quality, health and safety index system for agricultural products sold via e-commerce, which included 6 first-level and 13 second-level indices. The establishment of the index system provides a method for quality, health and safety regulation for agricultural products via e-commerce. In addition, based on the theory of Hazard Analysis and Critical Control Point (HACCP), this paper combed the key links and control points of quality and safety for agricultural products via e-commerce and provided an evaluation basis for the quality and safety management system of agricultural products under the e-commerce environment. Finally, in view of the shortcomings of the current quality and safety for agricultural products via e-commerce, and the development trend of the future electronic commerce of agricultural products, the paper put forward the countermeasures and suggestions. Keywords: agricultural products, e-commerce, quality and safety, supervision, management system DOI: 10.25165/j.ijabe.20181101.3005 Citation: Ma C, Wang D Y, Hu Z Q, Li Z. Considerations of constructing quality, health and safety management system for agricultural products sold via e-commerce. Int J Agric & Biol Eng, 2018; 11(1): 31–39.
Social and Institutional Origins of Political Islam

Under what conditions did the first Islamist movements organize? Which social and institutional contexts facilitated such mobilization? A sizable literature points to social and demographic changes, Western encroachment into Muslim societies, and the availability of state and economic infrastructure. To test these hypotheses, we match a listing of Muslim Brotherhood branches founded in interwar Egypt with contemporaneous census data on over 4,000 subdistricts. A multilevel analysis shows that Muslim Brotherhood branches were more likely in subdistricts connected to the railway and where literacy was higher. Branches were less likely in districts with large European populations, and where state administration was more extensive. Qualitative evidence also points to the railway as key to the movement’s propagation. These findings challenge the orthodoxy that contact between Muslims and the West spurred the growth of organized political Islam, and instead highlight the critical role of economic and state infrastructure in patterning the early contexts of Islamist activism.
Comparison of rabbit breed types for postweaning litter growth, feed efficiency, and survival performance traits.

Postweaning data on 643 rabbits from 122 litters representing four breed types, New Zealand White (NZW) and Californian (CAL) purebreds, CAL X NZW (CXN), and Flemish Giant (FG) crossbreds (the latter group was a collection of FG X CAL, FG X Champagne D'Argent [CHA], and 1/2 FG X 1/4 CAL X 1/4 CHA), were gathered over five seasons and compared for growth, feed efficiency, and survival-related performance traits. Evaluation criteria included litter size and weight at weaning (28 d); 28- to 70-d litter feed intake, weight gain, feed efficiency, and mortality rate; and litter and average market weight (70 d). The least squares model included main effects of breed type, season of birth of the litter and parity of dam, litter size at weaning as a linear covariate, and the random error. Breed-type differences were not detected for litter size and weight at weaning and feed efficiency. Purebred NZW and CAL litter trait performances were comparable (P greater than .05). Purebred NZW litters consumed less feed than CXN and FG crosses, gained weight less rapidly than FG crosses, and weighed less per fryer at 70 d than CXN and FG crosses (P less than .05). Feed intake was lower and average market weight was lighter for CAL purebred litters than for CXN and FG crossbred litters (P less than .05). The CXN and FG crossbreds only differed (P less than .05) for average market weight (2,078 vs 2,192 g). Mortality rate was lower (P less than .05) in CXN crossbred litters than in CAL purebred litters.(ABSTRACT TRUNCATED AT 250 WORDS)
Water Conveyance Tunnels

Water conveyance tunnels require special considerations regarding friction losses, drop shafts for vertical conveyance, air removal, control of infiltration and exfiltration, tunnel linings, lake taps and connections to live tunnels, and maintenance.
Statistical Tolerancing: The State of the Art: Part I. Background

The object of this paper is to review and illustrate the concept of statistical tolerancing and the methods which are applicable to assigning component tolerances. The approach is primarily theoretical, but the theory is that which is useful in practice..
Game Theory, Rationality and Evolution

The Theory of Games was conceived as a theory of interactive decisions for rational agents. The basic solution concept — that of Nash equilibrium — is built on rationality assumptions whose strength has only recently been made explicit. Refinements of Nash equilibrium, such as subgame perfection, require even stronger rationality assumptions. Here, it seems, is the pure domain of rational choice theory, where rational decision makers reflect on each others rational decisions, and rationality assumptions are multiplied by strategic interaction.
Lessons in early identification and treatment from a case of disabling vitamin C deficiency in a child with autism spectrum disorder

BackgroundAutism spectrum disorder is a heterogenous neurodevelopmental condition accompanied by a variety of associated features. Case reports suggest one such associated feature, food selectivity...
Impact of Data Availability and Resolution on Long-Term Sedimentation Estimates in a Storage Reservoir

AbstractThe sustainability of worldwide reservoirs is threatened by the reduction of their storage capacity caused by continuous sediment accumulation. Many reservoirs are filling in at rates highe...
Utilizing microwave communication data for detecting fog where satellite retrievals are challenged

This study shows the potential of microwave communication networks for the detection of fog in challenging conditions where satellite systems are often limited. In a first event, the ability to detect fog using commercial microwave links, at a time when the satellite cannot detect the phenomena due to high-level cloud cover obscuring the ground-level fog, is demonstrated. The ability of the microwave system to rule out ground-level fog at times when the satellite detects a low-lying stratus cloud, but cannot identify whether it is adjacent to the ground or at higher elevations above it, is demonstrated in a second event. The results indicate the operative potential of this technique to assist end users in reliable decision making that have highly important economic and safety implications.
Postoperative neutrophil-to-lymphocyte ratio as a predictor of surgical complications, recurrence-free (RFS), and overall survival (OS) among esophageal adenocarcinoma patients after induction chemoradiation followed by esophagectomy.

e15065 Background: Neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation. It has been previously used with variable success to predict overall survival of patients with solid ma...
Disowning Knowledge: Coriolanus and Interpretations of Politics

S omething that draws me to Coriolanus is its apparent disdain of questions I have previously asked of Shakespearean tragedy, taking tragedy as an epistcmological problem, a refusal to know or to be known, an avoidance of acknowledgment, an expression (or imitation) of skepticism. Coriolanus's refusal to acknowledge his participation in finite human existence may seem so obviously the fact of the matter of his play that to note it seems merely to describe the play, not at all to interpret it. It may be, however, that this lack of theoretical grip itself proposes a moral, or offers a conclusion, namely that Coriolanus is not exactly to be understood as a tragedy, that its mystery – supposing one agrees to something like a mystery in its events – will be located only in locating its lack or missing of tragedy, hence its closeness to tragedy. But systematically to pursue this possibility would require – from me – following out a sense that this play presents a particular interpretation of the problem of skepticism as such (skepticism directed toward our knowledge of the existence of others), in particular an interpretation that takes skepticism as a form of narcissism.