cssi/SciSciGPT-SciSciNet huggingface dataset:
A Monte Carlo study of the amylosic chain conformation

Monte Carlo studies of the unperturbed amylosic chain conformation have been carried out in the approximation of separable chain configuration energies. Sample chains of arbitrary chain length have been generated so as to be distributed consistent with refined estimates of the configuration energy and thus suitable for evaluation of averages of the desired configuration-dependent properties. Perspective drawings of representative chains from the Monte Carlo sample have been made for comparison with standard idealizations of amylosic chain conformation. He molecular model employed generates a randomly coiling chain possessing perceptible regions of left-handed pseudohelical backbone trajectory. Distribution functions for the end-to-end distance of short amylosic chains disclose some propensity for the chain to suffer self-intersections at sort range in the chain sequence, which may vitiate the usual amylosic chain models based on the assumed independence of sets of glycosidic linkage torsion angles. The amylosic persistence vector and persistence length have been calculated as a function of chain length for the chain model employed.
The structure of Colpoda elliotti n. sp.

SYNOPSIS. Colpoda elliotti n. sp., found in an enrichment culture from deer droppings, is a small (15–28 by 7.5–17 μ) member of the genus with prominent, rigid, tooth-like processes set between the kineties in the posterior 2/3 of the body. These “teeth” give it a distinctive outline even when viewed at low magnifications. The usual number of kineties is 12; the number of keel notches is 4. Multiplication occurs in reproductive cysts yielding typically 4 tomites. Thick-walled, resting cysts are also formed. The nuclear apparatus includes a single, crescentic ***micronucleus and a broadly elliptical macronucleus. The latter contains Feulgen-positive material in a few large masses, but no central nucleolus. The possibility that this species along with other members of the genas is perhaps more closely related to the Hymenostomatida than to the Trichostomatida as now defined is discussed.
Point Mutations Upstream of Hepatitis B Virus Core Gene Affect DNA Replication at the Step of Core Protein Expression

The pregenomic RNA directs replication of the hepatitis B virus (HBV) genome by serving both as the messenger for core protein and polymerase and as the genome precursor following its packaging into the core particle. RNA packaging is mediated by a stem-loop structure present at its 5' end designated the epsilon signal, which includes the core gene initiator AUG. The precore RNA has a slightly extended 5' end to cover the entire precore region and, consequently, directs the translation of a precore/core protein, which is secreted as e antigen (HBeAg) following removal of precore-derived signal peptide and the carboxyl terminus. A naturally occurring G1862T mutation upstream of the core AUG affects the bulge of the epsilon signal and generates a "forbidden" residue at the -3 position of the signal peptide cleavage site. Transfection of this and other mutants into human hepatoma cells failed to prove their inhibition of HBeAg secretion but rather revealed great impairment of genome replication. This replication defect was associated with reduced expression of core protein and could be overcome by a G1899A covariation, or by nonsense or frameshift mutation in the precore region. All these mutations antagonized the G1862T mutation on core protein expression. Cotransfection of the G1862T mutant with a replication-deficient HBV genome that provides core protein in trans also restored genome replication. Consistent with our findings in cell culture, HBV genotype A found in African/Asian patients has T1862 and is associated with much lower viremia titers than the European subgroup of genotype A.
Literacy Transition Strategies for Upper Elementary Students with Language-Learning Disabilities.

Learning to read is the number one education priority in this nation. For the most part, upper-elementary students with language-learning disabilities (LLD) have not been included in the many regional and state initiatives to improve reading achievement and instruction. This article discusses how our knowledge and research about teaching beginning reading effectively to young children in the general education classroom can be applied to students in Grades 4 through 6. Stages of reading acquisition in LLD, key transition points, and a comprehensive set of strategies for general and special educators and other professionals (e.g., speech—language pathologists) to foster literacy in older beginning readers are offered.
Comparison of supervised and unsupervised linear methods for recovering task-relevant activity in EEG

In this paper we compare three linear methods, independent component analysis (ICA), common spatial patterns (CSP), and linear discrimination (LD) for recovering task relevant neural activity from high spatial density electroencephalography (EEG). Each linear method uses a different objective function to recover underlying source components by exploiting statistical structure across a large number of sensors. We test these methods using a dual-task event-related paradigm. While engaged in a primary task, subjects must detect infrequent changes in the visual display, which would be expected to evoke several well-known event-related potentials (ERPs), including the N2 and P3. We find that though each method utilizes a different objective function, they in fact yield similar components. We note that one advantage of the LD approach is that the recovered component is easily interpretable, namely it represents the component within a given time window which is most discriminating for the task, given a spatial integration of the sensors. Both ICA and CSP return multiple components, of which the most discriminating component may not be the first. Thus, for these methods, visual inspection or additional processing is required to determine the significance of these components for the task.
REGULATION OF INITIATION OF DNA SYNTHESIS IN CHINESE HAMSTER CELLS : II. Induction of DNA Synthesis and Cell Division by Isoleucine and Glutamine in G1-Arrested Cells in Suspension Culture

Suspension cultures of Chinese hamster cells (line CHO), which had stopped dividing and were arrested in G1 following growth to high cell concentrations in F-10 medium, could be induced to reinitiate DNA synthesis and to divide in synchrony upon addition of the appropriate amounts of isoleucine and glutamine. Both amino acids were required to initiate resumption of cell-cycle traverse. Deficiencies in other amino acids contained in F-10 medium did not result in accumulation of cells in G1, indicating a specific action produced by limiting quantities of isoleucine and glutamine. In the presence of sufficient glutamine, approximately 2 x 10-6 M isoleucine was required for all cells to initiate DNA synthesis in a population initially containing 1.5 x 105 cells/ml. Under similar conditions, about 4 x 10-6 M isoleucine was required for all G1-arrested cells to progress through cell division. In contrast, 1 x 10-4 M glutamine was necessary for maximum initiation of DNA synthesis in G1 cells, along with sufficient isoleucine. A technique for rapid production of G1-arrested cells is described in which cells from an exponentially growing population placed in F-10 medium deficient in both isoleucine and glutamine or isoleucine alone accumulated in G1 after 30 hr.
Preservation of apple slices using ascorbic acid and 4-hexylresorcinol / Preservación de rodaj as de manzana con ácido ascórbico y 4-hexilresorcinol

The use of sulphites for the prevention of browning on fruits and vegetables is banned in the USA. The possible alternative use of ascorbic acid (AA), 4-hexylresorcinol (HR), and a mixture of both on apple slices was studied taking quality retention as a function of storage time as compared with similar products treated with sulphites. The mixture of ascorbic acid and 4-hexylresorcinol (AH) significantly inhibited the browning of vacuum packaged apple slices for up to 8 weeks during storage at 0.5 °C (p ≤ 0.001). Browning inhibition by AH was comparable to that achieved by sulphite and stronger than that of ascorbic acid (AA). In addition AH did not bleach the fruit tissue and therefore the colour of AH treated fruits was closer to the fresh apple pieces than those treated with sulphite. AH also reduced the total viable microbial counts by more than 10-fold as compared with AA treated and control apple pieces. AH treated apple pieces had a slightly firmer texture than the control and there were no adverse...
Spatio-temporal signatures of user-centric data: how similar are we?

Much work has been done on understanding and predicting human mobility in time. In this work, we are interested in obtaining a set of users who are spatio-temporally most similar to a query user. We propose an efficient way of user data representation called Spatio-Temporal Signatures to keep track of complete record of user movement. We define a measure called Spatio-Temporal similarity for comparing a given pair of users. Although computing exact pairwise Spatio-Temporal similarities between query user with all users is inefficient, we show that with our hybrid pruning scheme the most similar users can be obtained in logarithmic time with in a (1 + ∊) factor approximation of the optimal. We are developing a framework to test our models against a real dataset of urban users.
Unexpected Malignant Diagnosis in Colonic Biopsies: Malignant Transformation of Ovarian Mature Teratomas—Two Case Reports and Review of the Literature

Colorectal adenocarcinoma is the second cause of cancer-related deaths in the United States. The occurrence of squamous cell carcinoma in the colorectum is extremely unusual. Malignant transformation from mature cystic teratoma of the ovary is a rare event. The most common transformation is squamous cell carcinoma, followed by adenocarcinoma. It occurs more often in elderly patients, who usually present with advance disease. We report two unusual cases of postmenopausal women diagnosed with squamous cell carcinoma in colon biopsies. After surgical resections, the carcinoma was proven to be the result of malignant transformation of ovarian mature cystic teratomas. Since squamous cell carcinoma of the colorectum is extremely rare, the presence of squamous cell carcinoma in a colonic biopsy in a female patient should alert the clinicians to other possible primary sites, as seen in these cases.
Which phenotypic traits of Dictyostelium discoideum farmers are conferred by their bacterial symbionts

The bacterial partners in symbiotic relationships with eukaryotes can have a powerful effect on the phenotypic traits of the host. Here we explore this issue using a simple model eukaryote, Dictyostelium discoideum, and its facultative bacterial symbionts. Some clones of the social amoeba D. discoideum, called farmers, maintain symbiotic relationships with certain species of bacteria while other clones, called non-farmers, do not. D. discoideum farmer clones that carry bacterial symbionts in the genus Burkholderia have four distinct traits associated with the farming symbiosis: i) short slug migration distances, ii) symbiont transport, iii) prudent harvesting of bacteria, and iv) resistance to toxicity of the farmer-associated bacteria. These traits, with their advantages and disadvantages, could be either conferred by bacterial symbionts, or intrinsic to the amoebae that have been colonized by bacteria. We compared five farmers and five non-farmers, both with and without farmer-associated bacteria, to disentangle the direct effects of bacteria from those intrinsic to the host. We found that short migration distance and symbiont transport are bacterially conferred traits. Prudent harvesting seems to represent a trait influenced by bacteria but not entirely controlled by them. Resistance to farmer-associated Burkholderia is present whether or not the farmer clone is currently carrying it or has been cured and newly exposed. Taken together, these data suggest that the association between host farmer and Burkholderia is not recent.
Cross-Functional Integration at the Frontline of the Retail Channel

Cross-functional integration has become critical in the retail industry in part because marketing events have become more complex and increasingly more dependent on frontline employees for implementation. In recent years, research has highlighted the importance of marketing and logistics managers working together for marketing execution (Esper et al., 2010; Ellinger et al., 2006), but little is known about cross-functional integration at the frontline (Arndt et al., 2012). This research explores cross-functional integration across the frontline networks of two different distribution structures within a consumer package goods (CPG) firm. Thus, the integration literature will be extended beyond the corporate or team level, to the frontline of the firm. Further, this research expands knowledge of the contexts in which cross-functional integration takes place by investigating multiple ways frontline employees interact.
Effects of nonlinear frequency compression on speech identification in children with hearing loss.

Objectives This study evaluated effects of nonlinear frequency compression (NLFC) processing in children with hearing loss for consonant identification in quiet and for spondee identification in competing noise or speech. It was predicted that participants would benefit from NLFC for consonant identification in quiet when access to high-frequency information was critical, but that NLFC would be less beneficial, or even detrimental, when identification relied on mid-frequency cues. Further, it was hypothesized that NLFC could result in greater susceptibility to masking in the spondee task. The rationale for these predictions is that improved access to high-frequency information comes at the cost of decreased spectral resolution. Design A repeated-measures design compared speech-perception outcomes in 17 pediatric hearing aid users (9 to 17 years of age) wearing Naida V SP "laboratory" hearing aids with NLFC on and off. Data were also collected in an initial baseline session in which children wore their personal hearing aids. Children with a wide range of audiometric configurations were included, but all participants were full-time users of hearing aids with active NLFC. For each hearing aid condition, speech perception was assessed in the sound field by using a closed-set 12-alternative consonant-vowel identification measure in quiet, and a closed-set four-alternative spondee-identification measure in a speech-shaped noise or in a two-talker speech masker. Results No significant differences in performance were observed between laboratory hearing aid conditions with NLFC activated or deactivated for either speech-perception measure. An unexpected finding was that the majority of participants had no difficulty identifying the high-frequency consonant /s/ even when NLFC was deactivated. Investigation into individual differences revealed that subjects with a greater difference in audible bandwidth with NLFC on versus NLFC off were less likely to demonstrate improvements in high-frequency consonant identification in quiet, but were more likely to demonstrate improvements in spondee identification in speech-shaped noise. Group results observed in the initial baseline assessment using personal aids fitted with more aggressive NLFC settings than used in laboratory aids indicated better consonant identification accuracy in quiet. However, spondee identification in the two-talker masker was poorer with personal compared with laboratory hearing aids. Comparisons across personal and laboratory hearing aids are tempered, however, by the potential of an order effect. Conclusions The observation of comparable performance with NLFC on and NLFC off in the laboratory aids provides evidence that NLFC is neither detrimental nor advantageous when modest in strength. Results with personal hearing aids fitted with stronger compression settings than laboratory aids (NLFC on) highlight the critical need for further research to determine the impact of NLFC processing on speech perception for a wider range of speech-perception measures and compression settings.
Effect of Anti-Knock Additives on the Chemical Stability of Automotive Gasolines

We have experimentally studied the effect of anti-knock additives on the tendency of gasolines to undergo oxidation and to form gums during blending and storage. We propose a statistical approach to estimating the significance of the effect of anti-knock additives on the chemical stability of gasolines, and have established regression models for the variation in chemical stability as a function of the anti-knock additive content in the gasolines.
Rhythm of Oxygen Uptake in Diapausing Larvae of the Codling Moth at Several Temperatures

The oxygen uptake of larvae of the codling moth, Laspeyresia pomonella (L.) (Lepidoptera: Olethreutidae), in diapause, decreased from an average of 0.2 to loss than 0.05 microliters/milligram wet weight per hour at 26.6 and 11°C, respectively. At 20 and 23°C, a circadian rhythm of consumption was observed, but none was apparent at 11, 14, 17, or 26.6° C. About an 8-hour rhythm was determined for insects kept at 26.6°C, but this rhythm could not be validated statistically at the other test temperatures.
Mapping the road to analytical quality with charts of operating specifications

Quality is often described as a journey. In quality management programs, organizational change often gives the illusion of a journey even when it only represents temporary movement without any well-defined destination. Sometimes the change is only to describe where we have been and how we arrived at the present, rather than advancing us to where we need to be in the future. Laboratory programs in quality management need well-defined destinations, maps to guide us to those destinations, and careful planning to assure a smooth journey.
Vortex Lift Contributions in the Spanwise Plane in Flapping Wings

Vortices in the vicinity of the wingtip generate lift force in the spanwise plane of flapping wings. I n previous studies by the authors to determine the contribution of pure spanwise flow (flow parallel to the wing surface) to the overall lift force in flapping wings , vortex -like structures were identified in the spanwise plane. In classical fixed wing ae rodynamics, the presence of wingtip vortices has been shown to increase the lift locally near the tip. Additionally, the impingement of large vortices on the upper surface of delta wings is considered to contribute largely to the lift force at higher angle s of attack . It is thus proposed that vortices in the spanwise plane (streamwise vorticity) generate lift in a similar manner in flapping wings. Using a mechanical ornithopter with wings fabricated in -house, vortices were identified at several different lo cations along the span of the wing, and at numerous different points throughout the flapping cycle under a variety of operating conditions . The lift generated by these spanwise planar oriented vortices was quantified experimentally using Digital Particle I mage Velocimetry. After subtracting inertial effects from the total measured lift force via force transducer the vortex lift force was found to be significant.
Research of image pre-processing of well-logging based on wavelet transform

Based on wavelet transform,the image of well-logging can be decomposed in various scales.Wavelet coefficients are processed by several methods,including clearing wavelet coefficients of high frequency in small scales,processing under different threshold,modular maximum and enhancing wavelet coefficients of high frequency in large scales。Therefore,de-noising and enhancement come true.The results showed image preprocessing could be realized well based on wavelet transform.
Effects of the conjugation of whey proteins with gellan polysaccharides on surfactant-induced competitive displacement from the air-water interface

Whey proteins can be used to stabilize foams and emulsions against coalescence because of their ability to form viscoelastic films at the interface that resist film rupture on collision between colloidal particles. However, whey proteins are competitively displaced from the interface if small-molecule surfactants are added, leading to destabilization of the entire system. This is because surfactants are more effective in molecular packing at the interface, and they lower interfacial tension to a greater degree than whey proteins do, but their interfacial films are poor in viscoelasticity. We hypothesized that whey proteins would become more resistant to surfactant-induced competitive displacement if they were conjugated with network-forming polysaccharides. The protein moiety of the conjugate would be expected to enable its adsorption to the interface, and the polysaccharide moiety would be expected to form self-assembled networks, strengthening the interfacial film as a whole. In this study, whey proteins were conjugated with gellan polysaccharides using the Maillard reaction. Atomic force microscopy images of interfacial films formed by the whey protein-gellan conjugate at the air-water interface and transferred onto mica sheets using the Langmuir-Blodgett method revealed that gellan did form self-assembled networks at the interface and that interfacial films also contained a large number of unconjugated whey protein molecules. Following the addition of a small-molecule surfactant (Tween 20) to the sub-phase, surface pressure increased, indicating spontaneous adsorption of surfactants to the interface. Atomic force microscopy images showed decreases in interfacial area coverage by whey proteins as surface pressure increased. At a given surface pressure, the interfacial area coverage by whey protein-gellan conjugates was greater than coverage by unconjugated whey proteins, confirming that whey proteins became more resistant to surfactant-induced displacement after conjugation with gellan. Furthermore, gellan molecules added to the sub-phase after the formation of a monolayer of whey proteins at the air-water interface did not adsorb to the interfacial protein film. These results provide a molecular basis for designing interfacial structures to enhance the stability of colloidal systems.
A Comparison of Coupon Usage Behavior Between Afro-, Caucasian- and Chinese-Americans

This study was undertaken to compare coupon usage behavior between Afro-Americans, Caucasian-Americans and Chinese-Americans. The following areas were analyzed: types of coupons used, frequency of use, source of coupons and desired monetary face values. The results imply that Afro-Americans, Caucasian-Americans and Chinese-Americans use coupons and have similar coupon usage behavior.
Genetic Identification of a PilT Motor in Geobacter sulfurreducens Reveals a Role for Pilus Retraction in Extracellular Electron Transfer.

The metal-reducing bacterium Geobacter sulfurreducens requires the expression of conductive pili to reduce iron oxides and to wire electroactive biofilms, but the role of pilus retraction in these functions has remained elusive. Here we show that of the four PilT proteins encoded in the genome of G. sulfurreducens, PilT3 powered pilus retraction in planktonic cells of a PilT-deficient strain of P. aeruginosa and restored the dense mutant biofilms to wild-type levels. Furthermore, PilT3 and PilT4 rescued the twitching motility defect of the PilT-deficient mutant. However, PilT4 was the only paralogue whose inactivation in G. sulfurreducens lead to phenotypes associated with the hyperpiliation of non-retractile mutants such as enhanced adhesion and biofilm-forming abilities. In addition, PilT4 was required to reduce iron oxides. Taken together, the results indicate that PilT4 is the motor ATPase of G. sulfurreducens pili and reveal a previously unrecognized role for pilus retraction in extracellular electron transfer, a strategy that confers on Geobacter spp. an adaptive advantage for metal reduction in the natural environment.
Media Components and Preparation

Plant tissue culture medium components can and do vary; this chapter divides the components in most cell culture media into the inorganic salts, plant growth regulators, vitamins, carbohydrates, hexitols, gelling agents, amino acids, antibiotics, natural complexes, pH and preparation of a medium. All of these components must be carefully considered when developing a medium for any specific plant or purpose. The information presented will guide the beginning student or researcher in the process of plant cell culture preparation.
Smart Watch Potential to Support Augmented Cognition for Health-Related Decision Making

In this paper, we review current smart watch research in the health domain to inform an Augmented Cognition (AugCog) research agenda for health-related decision making and patient self-management. We connect this AugCog research agenda to prior Clinical Decision Support (CDS), workflow, and informatics research efforts using Persons Living With HIV (PLWH) and Chronic Obstructive Pulmonary Disorder (COPD) patients as examples to illustrate potential research directions.
The influence of self heating on the measurement of hot carrier degradation in high voltage n-channel LDMOS

A systematic study of self heating caused by hot-carrier (HC) stress in packaged thick gate oxide HV LDMOS devices (Laterally Diffused MOSFETs), and how self heating significantly affects HC degradation characteristics is presented. The time delay between the removal of the HC stress and the parameter measurement significantly affected the measured HC Idlin/Rdson degradation with longer delay times resulting in less observed Idlin degradation. We show the recovery of degradation observed with longer delay times was mostly due to self heating effects, as opposed to interface trapped charge related recovery. HC stress at wafer level with different relaxation times exhibits almost no recovery on Idlin/Rdson degradation. The HC Idlin degradation caused by the self heating effect is observed in packaged HV LNDMOS devices but not in wafer level tests. A method is proposed to eliminate the influence of the self heating effect on HC measurement.
Indigenous Healing Practices and Asian Immigrant Women

ABSTRACTThe current article highlights the importance of indigenous psychology for Asian immigrant women. A brief overview is provided about Asian American immigration and the importance of understanding women’s experiences with the contextual lens of gender, ethnicity, and race. Key values relevant to help-seeking and service utilization are also presented. Complementary alternative approaches to Western-based mental health treatment are discussed as ways in which feminist and multicultural treatment approaches can be integrated. Given the inherent diversity of Asians and Asian Americans, which includes over 60 ethnic subgroups, the article is not meant to provide an exhaustive list of available native practices nor to reflect the experiences of Asians as a homogenous group. Instead, the goal of this article is to provide readers with an understanding of how culturally based healing practices and concepts are needed to complement and contribute to our extant understanding of help-seeking. We conclude by ...
Dose finding study of the intratumoral administration of the oncolytic polio/rhinovirus recombinant (PVSRIPO) against WHO grade IV malignant glioma (MG).

e13533Background: The live attenuated oral poliovirus vaccine was modified to contain a heterologous internal ribosomal entry site stemming from human rhinovirus type 2, creating PVSRIPO. PVSRIPO r...
The Presidential Debates 2016

Ben Voth examines the 2016 presidential debates. He begins by noting the rhetorical significance of the 2016 debates and identifies four essential ingredients of a debate. In reviewing the presidential primary debates, Voth explains why 2016 was a blockbuster year with so many initial candidates among the Republicans and a surprisingly tough contest for the Democrats between Clinton and Sanders. Voth addresses the unprecedented role and impact of the media on the debates. Trump received overwhelmingly more negative press than Clinton and the moderators became active participants during the debates. Voth concludes with considerations of why Trump’s vulgarity and offensive arguments worked and five lessons from the debates that will influence the 2020 presidential debates.
Insights for Measuring Social Value: Classification of Measures Related to the Capabilities Approach

The measurement of performance and the evaluation of social change efforts are vital yet challenging issues for practitioners and researchers in the social sector. Although tools exist to measure social value, they tend to focus on converting non-monetary costs and benefits into monetary terms to demonstrate the cost-effectiveness of operations. The capabilities approach provides a value-based alternative that could potentially enable a broader assessment of a project’s impact; this approach encapsulates societal-level factors, beneficiary perspectives, and a more holistic view of a beneficiary’s life. Ultimately, our goal is to raise the following question in the social sector field: what might a capabilities approach to social value measurement that is suitable for practical application by social sector organizations look like? The purpose of this article is to introduce the theoretical framework and to present what some of the measures and instruments might look like, at least in part, based on applications in other contexts.
Suicide behaviour among Guyanese orphans: identification of suicide risk and protective factors in a low- to middle-income country.

Objective: Suicide is the leading cause of death among youth in Guyana, a low- and middle-income country (LMIC), which globally ranks first in female adolescent suicides over the last decade. Worldwide, Guyana has experienced the largest increase in youth suicide, despite focused public health efforts to reduce suicide. Further, youth in Guyana, who are clients of the orphanage system and have faced early childhood trauma, may have an additive risk for suicide. Guided by an ideation-to-action theoretical framework for suicide prevention, the goal of the proposed research study is to describe and identify risk and protective factor correlates of youth suicidal behaviour among those at highest risk for suicide – orphans who reside in a LMIC institutional setting. Methods: In a preliminary sample of 25 orphan youth, one licensed psychologist and two social workers administered the DSM-5 Level 1 Cross-Cutting Symptom Measure and Behavioural Assessment Schedule for Children, 2nd Edition (BASC-2) during a semi-...
The redox requirements of proliferating mammalian cells

Cell growth and division require nutrients, and proliferating cells use a variety of sources to acquire the amino acids, lipids, and nucleotides that support macromolecule synthesis. Lipids are more reduced than other nutrients, whereas nucleotides and amino acids are typically more oxidized. Cells must therefore generate reducing and oxidizing (redox) equivalents to convert consumed nutrients into biosynthetic precursors. To that end, redox cofactor metabolism plays a central role in meeting cellular redox requirements. In this Minireview, we highlight the biosynthetic pathways that involve redox reactions and discuss their integration with metabolism in proliferating mammalian cells.
Pioneers in Unknown Territory: Teacher Perceptions and Use of Non-Conventional Instructional Tools

In an ongoing effort to understand teacher adoption of innovative instructional practices and their consideration of non-conventional tools for teaching and learning we collected survey data from over 300 teachers. From the 44 teachers who participated in our research we found a lack of alignment between teacher personal use of technology for teaching, high levels of teacher-centered use of technology and low levels of student-centered access to technology for learning, and need for instructional technology professional development that is different than what the teachers are receiving. Our discussion includes possible explanations, implications, and directions for future research.
What We Do: A Nonreductive Approach to Human Action

“What is left over,” Wittgenstein once asked, “if I subtract the fact that my arm goes up from the fact that I raise my arm?”1 In this paper, I shall try to give a nonreductive and nondualistic answer to this question. First, I shall simply present a view of human action that allows a straightforward answer to Wittgenstein’s question, and then show how this view of human action fits into a general conception of what a human person or agent is. Next, I shall show how this view can handle what Jaegwon Kim has called ‘the problem of explanatory exclusion.’ Finally, I shall offer reasons why a nonreductive approach to action is needed.
Resiliency in Pediatric Chronic Illness: Assisting Youth at School and Home

This chapter is intended to provide the reader with a perceptive of how resiliency plays a role in youth’s adjustment and management of chronic medical conditions. We will draw upon theory and empirical research to build a case for the need for psychological evaluations and interventions to incorporate an individual and family resiliency perspective to aid youth and their families in having more positive outcomes, such as better disease control, healthier interpersonal relationships, and greater self-confidence in their own abilities. Further, youth with chronic illnesses are at particular risk for difficulties in school. Thus, we will also highlight strategies that may work to promote better school functioning. In order to demonstrate these connections, we will draw upon case examples and present data from a study focused on integrating medical, mental health, and school psychological services for adolescents with diabetes.
Isolation of a cDNA clone encoding a zinc finger protein highly expressed in T-leukemia lines.

A cDNA clone encoding a novel zinc finger protein expressed in lymphoid cells has been isolated. This protein contains 5 repeats of the C2H2 motif previously described in the Drosophila gap gene, Kruppel, which is involved in embryo segmentation. Northern blot analysis showed that the messenger RNA (mRNA) encoding this protein is expressed at high levels in a variety of T-leukemia cell lines, at lower levels in some B cells, but is not observed in nonlymphoid cells. Within the T lineage, the mRNA is found at high levels in both alpha beta and gamma delta T cells. These data suggest that this cDNA, designated Hkr-T1, represents a gene that may contribute to the determination of the differentiation and the specificity within lymphoid cells.
Electron-impact excitation of forbidden and allowed transitions in Fe II

Extensive calculations are reported for electron collision strengths, rate coefficients, and transitions probabilities for a wide range of transitions in Fe ii. The collision strengths were calculated in the close-coupling approximation using the B-spline Breit-Pauli R-matrix method. The multiconfiguration Hartree-Fock method in connection with adjustable configuration expansions and a semiempirical fine-tuning procedure is employed for an accurate representation of the target wave functions. The energy correction was also used in the scattering calculations by adding to Hamiltonian matrices prior to transformation to intermediate coupling. The spin-orbit interaction term was added to the final Hamiltonian matrices in scattering calculations. The close-coupling expansion contains 340 fine-structure levels of Fe ii and includes all levels of the $3{d}^{6}4s$, $3{d}^{5}4{s}^{2}$, $3{d}^{7}$, and $3{d}^{6}4p$ configurations, plus a few lowest levels of the $3{d}^{5}4s4p$ configuration. The effective collision strengths are obtained by averaging the electron collision strengths over a Maxwellian distribution of velocities at electron temperatures in the range from ${10}^{2}$ to ${10}^{5}$ K and are reported for all possible inelastic transitions between the 340 fine-structure levels. The present results are more extensive than the previous calculations and considerably expand the existing data sets for Fe ii, allowing a more detailed treatment of the available measured spectra from different space observatories. Comparison with other calculations for collision rates and available experimental radiative rates is used to place uncertainty bounds on our collision strengths and to assess the likely uncertainties in the existing data sets.
Outcomes of parathyroidectomy for primary hyperparathyroidism with nonlocalizing preoperative imaging.

Background The purpose of this study was to evaluate our surgical experience in patients with primary hyperparathyroidism (PHPT) with nonlocalizing sestimibi and ultrasound scans. Methods A retrospective review of 521 patients treated from April 2005 to July 2017 at Loma Linda University Medical Center who received parathyroidectomy for PHPT. One hundred forty-seven patients (28%) had double negative localization (nonlocalizing sestamibi and ultrasound). Results Surgical cure for PHPT was 97.3% and 99.2% with nonlocalized and localized disease, respectively, and complication rates were similar between groups. Preoperative parathyroid hormone and gland weight were significantly lower with nonlocalization. The incidence of multigland disease (MGD) was greater in patients with nonlocalization on sestamibi and ultrasound. Conclusion Nonlocalization of parathyroid glands was not associated with decreased cure rate or increased morbidity. The presence of MGD and requirement for more extensive surgery were greater in patients with nonlocalizing disease.
Coalitional game theory based local power exchange algorithm for networked microgrids

Abstract The future distribution network may encompass a large number of microgrids, in which case local networked microgrids can be formed and all the microgrids in the network be connected to the main grid through a distribution sub-station. To improve the efficiency of the entire network rather than focusing on improving the efficiency and reliability of each microgrid, this paper proposes a coalitional-game-theory-based local power exchange algorithm to identify incentives for coalitional operation and help microgrids in the network trade power locally with neighboring microgrids, so as to meet their own power requirements while achieving higher expected individual utility. Compared with the traditional operation situation, simulation results show that the proposed coalitional- game-theory-based local power exchange algorithm can help increase individual microgrid utility in the network. When there are 30 microgrids in the network, for example, each microgrid is expected to have a 16% increment of individual utility on average.
New Model for Simulating Hydrologic Processes under Influence of Surface Depressions

AbstractSurface depressions significantly influence hydrologic processes. In traditional semidistributed models, however, the entire area is connected to the outlet of a watershed and surface depre...
The Na + /H + Exchanger: A Target for Therapeutic Intervention in Cerebral Ischemia

The mammalian Na+/H+ exchanger (NHEs) family is a group of integral membrane transport proteins. It mediates an electroneutral 1:1 exchange of intracellular H+ for extracellular Na+ and in doing so regulates intracellular pH (pHi) homeostasis and cell volume. NHEs contain two functional domains: the N-terminal transmembrane domain, which is necessary and sufficient to catalyze ion translocation, and the C-terminal cytoplasmic domain, which is crucial for modulating NHE1 activity.
Addressing the Mental Health Needs of Post-Secondary Students: Considerations for College Administration

Anxiety and depression are the leading causes for diminished performance and quality of life for students in their post-secondary academic career. The effects range from poor grades and dropping out to substance misuse and even suicide amongst members of student bodies nationwide. Students who are unaware of resources available to them are at risk of having these issues exacerbated over time. It is the responsibility of college administrations to prepare students for a life after college and, therefore, must enhance the treatment services and education of said services to the student bodies as a whole to alleviate these problems and to attempt to deter falling retention rates and potential tragedies on campuses.
Clinical Text Summarization with Syntax-Based Negation and Semantic Concept Identification.

In the era of clinical information explosion, a good strategy for clinical text summarization is helpful to improve the clinical workflow. The ideal summarization strategy can preserve important information in the informative but less organized, ill-structured clinical narrative texts. Instead of using pure statistical learning approaches, which are difficult to interpret and explain, we utilized knowledge of computational linguistics with human experts-curated biomedical knowledge base to achieve the interpretable and meaningful clinical text summarization. Our research objective is to use the biomedical ontology with semantic information, and take the advantage from the language hierarchical structure, the constituency tree, in order to identify the correct clinical concepts and the corresponding negation information, which is critical for summarizing clinical concepts from narrative text. We achieved the clinically acceptable performance for both negation detection and concept identification, and the clinical concepts with common negated patterns can be identified and negated by the proposed method.
Identification of durum wheat cultivars and their tetraploid relatives with low cadmium content.

In this study, 71 durum wheat cultivars (Triticum durum Desf.), 22 emmer wheat (Triticum dicoccum L.) and 11 wild emmer (Triticum dicoccoides L.) genotypes were genetically characterized to determine the alleles associated with high cadmium (Cd) content. After genotypic characterization, 14 cultivars selected among all genotypes with low and high Cd content were phenotyped by a pot experiment to verify the genotypic data. Identification of 32 durum wheat, one emmer wheat and four wild emmer genotypes showed that they have alleles associated with high Cd content, while 68 genotypes of which 39 durum wheat, 21 emmer wheat and 7 wild emmer cultivars had alleles associated with low Cd content, respectively. Moreover, phenotypic data obtained from pot experiment were similar to the molecular data. To sum up, the marker successfully classified durum wheat cultivars into either high or low accumulators and these results can be safely used in breeding programs to improve new durum wheat cultivars with alleles associated with low Cd content. Due to routine use of phosphorus fertilizers in agricultural areas and other anthropogenic factors related to Cd toxicity, new durum wheat cultivars with low Cd content should be urgently developed for safe production of macaroni or other types of wheat products for human and animal consumption.
Changes in association between school foods and child and adolescent dietary quality during implementation of the Healthy, Hunger-Free Kids Act of 2010.

Abstract Purpose The purposes of the study were to estimate the effect of Healthy, Hunger-Free Kids Act of 2010 (HHFKA) implementation on dietary quality of all U.S. school-aged children and adolescents and examine whether those effects differed by the demographic group. Methods We used survey regression on 2007–2016 National Health and Nutrition Examination Survey data to estimate the proportion of energy intake from school foods and the association between school food intake and dietary quality, before and after HHFKA passage/implementation. To account for demographic changes in the U.S. population over time, inverse probability weighting was used. The product of the proportion of energy from school foods and the association between school food intake and dietary quality estimated the effect of HHFKA implementation on dietary quality. Results School food intake quantity remained stable during the study period. HHFKA implementation improved students’ dietary quality by 4.3 Healthy Eating Index-2010 points (95% confidence interval: 2.5, 6.1) on days when school foods were eaten and by 1.3 Healthy Eating Index-2010 points (95% confidence interval: 0.73, 1.8) averaged over all days annually. Conclusions HHFKA implementation improved the total dietary quality of U.S. school students. U.S. students would benefit from eating school meals in the post-HHFKA era, and HHFKA regulations should not be relaxed.
Three A’s to Inclusive Access: Tarrant County College’s Case Story

Inclusive access provides a digital textbook option for students that is higher quality/lower cost and accessible to students on the first day of class with a print option. Tarrant County College (TCC) inclusive access initiative (branded “TCC Plus”) provides an additional option for faculty to adopt course materials which will increase access, affordability, and achievement. Dr. Mark McClendon, vice-chancellor of finance, and Dr. Tyson McMillan, professor of computer science and former president of the Joint Consultation Committee, cochaired a cross-functional task force to plan and implement this initiative. The scope of the project included three precepts: (1) student focused, (2) faculty driven, and (3) administratively supported. In this case study, we provide process, procedures, and data points that resulted from Spring 2018 to Fall 2019 semesters at TCC. This work will focus on the decision-making process, how our strategic thinking evolved, the critical elements of the program, and future steps. Additionally, this case study explores to what extent the TCC Plus program increases access, affordability, and achievement for students, while continuing with the college mission of improving student persistence and graduation rates.
Multiphase CT Angiography: A Useful Technique in Acute Stroke Imaging—Collaterals and Beyond

Multiphase CTA offers several important advantages over the traditional single-phase CTA technique in acute ischemic stroke, including improved detection of large-vessel occlusion, improved characterization of collateral status, improved tolerance of patient motion and poor hemodynamics, and higher interrater reliability. These benefits are gleaned at little additional cost in terms of time, risk to the patient, and capital expense. Existing data suggest that there are important benefits to using multiphase CTA in lieu of single-phase CTA in the initial vessel assessment of patients with acute stroke.
First principles study of thermoelectric properties of β-gallium oxide

The thermoelectric effects in bulk β-gallium oxide crystals are investigated in this work using the ab initio calculated electron-phonon interactions and semi-classical Boltzmann transport theory. We have taken all major scattering mechanisms into account, namely, polar and non-polar optical phonon, acoustic phonon, and ionized impurity scattering. To accurately account for the polar phonon scattering rate, we take into account the dynamic screening at higher electron densities. An iterative solution of the Boltzmann transport equation is used in order to account for the inelastic and anisotropic nature of polar optical phonon scattering. The thermoelectric transport coefficients, Seebeck coefficient, Peltier coefficient, and electronic thermal conductivity, are calculated for a wide range of temperatures and doping densities. The calculated Seebeck coefficient is compared with the experimentally measured value and found to be in good agreement considering the mobility of the samples. The value of the Seebeck coefficient at 300 K is found to be −341 μ V K − 1, which is high compared to that of the other commonly studied semiconductors. The larger Seebeck coefficient is due to the higher density of states arising from comparatively high electron effective mass.
James V. Schall and the Augustinian Recovery of Political Philosophy

The aim of this essay is to articulate the unique approach toward recovering the practice of political philosophy in the work of James V. Schall. In the first part of the essay, I will provide a de...