cssi/SciSciGPT-SciSciNet huggingface dataset:
Emotional Behaviors, Emotivational Goals, Emotion Strategies: Multiple Levels of Organization Integrate Variable and Consistent Responses

Researchers have found undeniable variability and irrefutable evidence of consistencies in emotional responses across situations, individuals, and cultures. Both must be acknowledged in constructing adequate, enduring models of emotional phenomena. In this article I outline an empirically-grounded model of the structure of the emotion system, in which relatively variable actions may be used to pursue relatively consistent goals within discrete emotion syndromes; the syndromes form a stable, coherent set of strategies for coping with crises and opportunities. I also discuss a framework that can integrate dimensional and discrete perspectives on emotions.
Violence, Volksgemeinschaft and Empire: Interpreting the Third Reich in the Twenty-first Century:

Tim Kirk, Nazi Germany, New York, Palgrave, 2007; 304 pp.; £19.99 pbk; ISBN 0333600738 Dietmar and Winfried Suss (eds), Das Dritte Reich: Eine Einfuhrung, Pantheon, 2008; 393 pp.; €14.95 pbk; ISBN 9783570550441 Roderick Stackelberg, Hitler's Germany: Origins , Interpretations , Legacies, London, Routledge, 2009; 416 pp.; £22.99 pbk; ISBN 04 1 53733 IX Peter Reichel, Harald Schmid and Peter Steinbach (eds), Der Nationalsozialismus: Die Zweite Geschichte , Miinchen, C.H. Beck, 2009; 496 pp.; €29.90 pbk; ISBN 9783406583421 Hans Ulrich Wehler, Der Nationalsozialismus: bewegung, Fuhrerherrschaft, Verbrechen , Miinchen, C.H. Beck, 2009; 315 pp.; €19.90 pbk; ISBN 9783406584862
Residual modeling in music analysis-synthesis

In analysis-synthesis of musical sounds based on a sinusoidal model, the difference between the original signal and the synthesized signal, termed the residual, is typically a broadband noise process. It contains such musical phenomena as flute breath noise or violin bow noise. Synthesis without such "noise" tends to sound artificial; it is desirable to improve the synthesis realism by modeling the residual in such a way that it can be reinjected in the synthesized signal. This paper deals with a model of noise perception based on the equivalent rectangular bands (ERBs) of the auditory system. Since a broadband noise is perceptually well-represented by the time-varying energy in each of these frequency bands, the residual is parametrized in terms of these energies in the proposed model. An application of the model to music synthesis based on the inverse fast Fourier transform (FFT) is described in detail.
A 62-Year-Old Woman With Chronic Cough and Bronchospasm

62-year-old woman presented with chronic productive cough, intermittent wheezing, and shortness of breath over a 5-year period. She was a nonsmoker and had no history of environmental exposure to chemicals or dust. Her medical history was notable for nasopharyngeal cancer (NPC) treated with radiation therapy 26 years previously that resulted in mild dry mouth and hoarseness, nasal polyp, and chronic sinusitis. During the past 5 years, she underwent a series of examinations that revealed positive bronchodilator test and mild hyperinfl ation of lung parenchyma on chest radiograph. She received maintenance therapy with inhaled bronchodilator and corticosteroids, antihistaminics, and xanthine under the impression of chronic asthma and sinusitis, and antibiotics and oral corticosteroids during episodes of acute exacerbation. However, the clinical course fl uctuated, with deterioration of symptoms on climatic changes or following upper respiratory tract infection. Even though the patient denied being aware of any episodes of aspiration, she was hospitalized and treated as having aspiration pneumonia on four occasions. Yet, no advanced study was performed to evaluate her swallowing function. Tracing back her history, she experienced occasional choking episodes while drinking, but did not pay attention to them. Over the past year, her symptoms of productive
On the use of IGBT-gated GTO-cascode switches in quasi-resonant converters

The use of an insulated-gate bipolar transistor (IGBT) to improve the switching performance of a gate turn-off (GTO) thyristor in a cascode switch is documented. The IGBT-gated GTO-cascode switch features simple drive requirement, fast switching, robustness, and overcurrent protection. The cascode switch was applied in a quasi-resonant buck power converter and simulated on a computer using PSpice. The IGBT-gated GTO-cascode switch is suitable for high-power (1200 V, 140 A) and high-frequency operation up to 30 kHz. The turn-off time of the main switch, GTO, is reduced significantly due to the reverse current gain of unity in cascode configuration. >
Development of an Ex Vivo Assay for Use as a Surrogate Model to Assess the Impact of Endotoxin on Cattle

Current guidelines used by the US Food and Drug Administration to establish a safe level of pyrogens in veterinary parenteral products were derived from work designed for products intended for human use, and there is no consensus on what levels of endotoxin or other pyrogens are safe for domestic animals. The accepted biological measures for endotoxins and other pyrogens have been based on measurement of relatively small changes in body temperature in rabbits rather than an assessment of the inflammation caused by the endotoxins. It is difficult to accurately assess the small changes in body temperature caused by low levels of endotoxin in food-producing animals such as dairy cattle. Thus, the true relevance of guidelines to domestic animals is unknown. Accordingly, a whole-blood assay as a measure of endotoxin-induced inflammation was developed to serve as an in vitro surrogate model for either the rabbit pyrogen test or tests in cattle. Induction of interleukin-6 (IL-6) mRNA occurred at concentrations of lipopolysaccharide that ranged from 1 μg/mL through 1 pg/mL. Because there were still differences in IL-6 induction compared with unstimulated cultures, blood from a second set of animals was treated with lipopolysaccharide concentrations ranging from 1 μg/mL to 1 fg/mL. These results demonstrated that induction of IL-6 occurred somewhere between 100 fg/mL and 1 pg/mL. Because the most sensitive chemical assay can detect endotoxin only at a similar range, the whole-blood assay may be a biological assay that could be used in place of the rabbit pyrogen assay.
Measurement of protein flux with positron emission tomography in neonates

AIM To determine whether abnormal transvascular protein flux can be measured with positron emission tomography (PET) in neonates with respiratory distress syndrome (RDS). METHODS Fourteen infants with normal gas exchange (non-RDS group) underwent one PET measurement and 12 infants with RDS (the RDS group) underwent two measurements of protein flux, as determined by the pulmonary transcapillary escape rate for 68 Gallium labelled transferrin (PTCER). RESULTS The mean PTCER for the RDS infants (132 ± 39 10 -4 /min) was significantly greater than that for infants without RDS (75 ± 27 10 -4 /min). PTCER did not change between measurements in the infants with RDS, including five who received and responded to surfactant replacement between the two scans. CONCLUSIONS Increased transvascular flux of large molecular weight proteins complicates RDS in preterm infants. PET provides a tool with which to evaluate the processes that contribute to pulmonary dysfunction in neonates.
The “Real Self” and Inauthenticity: The Importance of Self-Concept Anchorage for Emotional Experiences in the Workplace

I examine the utility of self-concept anchorage (as described by Turner 1976) in the analysis of inauthenticity in the workplace. As controlling internally felt emotion may distance the worker from...
Implementation of strong mobility for multi-threaded agents in Java

Strong mobility, which allows multithreaded agents to be migrated transparently at any time, is a powerful mechanism for implementing a peer-to-peer computing environment, in which agents carrying a computational payload find available computing resources. Existing approaches to strong mobility either modify the Java virtual machine or do not correctly preserve the Java semantics when migrating multithreaded agents. We give an overview of our implementation strategy for strong mobility in which each agent thread maintains its own serializable execution state at all times, while thread states are captured just before a move. We explain how to solve the synchronization problems involved in migrating a multithreaded agent and how to cleanly terminate the Java threads in the originating virtual machine. We present experimental results that indicate that our implementation approach is feasible in practice
Feasibility of using text messaging for unhealthy behaviors screening in a clinical setting: a case study on adolescent hazardous alcohol use

Underage alcohol use is the leading cause of preventable mortality among adolescents in the USA. Moreover, the average age of onset of underage drinking is 13 years. This study examined the feasibility of using a text messaging survey (TMS) to assess adolescent alcohol use. A sample of 29 adolescents, aged 13–17 years, was recruited from two primary care clinics. They completed a 16 question TMS while in the waiting room and a two-question exit TMS. The participation rate was 87%. Two out of 25 (8%) adolescents met the criteria for hazardous drinking and 28% reported alcohol use. It was found that 38% and 25% of adolescents who completed the exit TMS were asked or advised about drinking, respectively. Text messaging to assess adolescent alcohol use in this setting seems feasible, does not disrupt patient workflow, and can assess many health behaviors before a clinical encounter.
College students and use of K2: an emerging drug of abuse in young persons

Background: K2 or “spice” has emerged as a popular legal alternative to marijuana among adolescents and young adults. However, no data has been published assessing prevalence of and associations with ever K2 use in any population. This study’s aims were to examine prevalence of ever K2 use among a sample of college students, to determine characteristics of persons who use K2, and to access the association between K2 and other drug use. Findings: Ever use of K2 was reported by 69 (8%) of the sample of 852 college students. Response rate was 36%. Bivariate and multivariate analyses assessed whether sociodemographic characteristics and other drug use were associated with ever use of K2. Ever use of K2 was reported by 69 (8%) of the sample. Among these 69 individuals, 61 (88%) had used a cigarette and 25 (36%) had used a hookah to smoke K2. In multivariate analyses, K2 use was more common in males (vs. females, adjusted Odds Ratio (aOR) = 2.0, 95% Confidence Interval (CI) = 1.2-3.5, p = 0.01) and 1 st or 2 nd year college students (vs. 3 rd year or above, aOR = 2.4, 95% CI = 1.2-5.0, p = 0.02). Conclusions: Ever use of K2 in this sample was higher than ever use of many other drugs of abuse that are commonly monitored in adolescents and young adults. Although DEA had banned five synthetic cannabinoids recently, clinicians and public health officials concerned with substance abuse in youth should be aware of and monitor the use of this drug in college students over time.
Designing RF control subsystems using the VXIbus standard

Various components are being designed to control the RF system of the 7-GeV Advanced Photon Source (APS). The associated control electronics (phase shifters, amplitude modulators, phase detectors, automatic tuning control, and local feedback control) are designed as modular cards with multiple channels for ease of replacement as well as for compact design. Various specifications of the VXIbus are listed and the method used to simplify the design of the control subsystem is shown. A commercial VXI interface board was used to speed the design cycle. Required manpower and actual task times are included. A discussion of the computer architecture and software development of the device drivers which allowed computer control from a VME processor located in a remote crate operating under the Experimental Physics and Industrial Controls Software (EPICS) program is also presented. >
Highly resistant HIV-1 proteases and strategies for their inhibition

The virally encoded protease is an important drug target for AIDS therapy. Despite the potency of the current drugs, infections with resistant viral strains limit the long-term effectiveness of therapy. Highly resistant variants of HIV protease from clinical isolates have different combinations of about 20 mutations and several orders of magnitude worse binding affinity for clinical inhibitors. Strategies are being explored to inhibit these highly resistant mutants. The existing inhibitors can be modified by introducing groups with the potential to form new interactions with conserved protease residues, and the flexible flaps. Alternative strategies are discussed, including designing inhibitors to bind to the open conformation of the protease dimer, and inhibition of the protease-catalyzed processing of the Gag-Pol precursor.
Biodegradable plastics derived from micro-fibrillated cellulose fiber and chitosan

We have been carrying out studies to develop biodegradable plastics from natural polysaccharides. We have found that a combination of micro-fibrillated cellulose fiber and chitosan produces a useful material that can be used to form biodegradable film and moldings. Cellulose-chitosan composite film demonstrate higher strength than general purpose plastic films, and wet strength peaks when chitosan content is 10-20%. The relatively small amount of chitosan needed is economically convenient because chitosan is more expensive than cellulose. This film biodegrade well in soil, completely dissolving and disappearing in two months. Biodegradability is influenced by the temperature used in thermal treatment the film, the quantity of acid groups in the cellulose, and other factors. These characteristics will be used to control decomposition. Since cellulose-chitosan plastics are not thermoplastics, we have been working on joint research with companies to produce films, nonwoven fabrics and foams. We discuss here the properties and application of these composite moldings.
Non-Enzymatic Remodeling of Fibrin Biopolymers via Photothermally Triggered Radical-Generating Nanoparticles

Thrombosis is a hallmark of several chronic diseases leading to potentially fatal heart attacks and strokes. Frontline interventions include intravenous delivery of potent, enzymatic fibrinolytics that possess a high risk for inducing systemic bleeding. As a conceptual countermeasure, we have developed a water-soluble PEGylated gold nanoparticle appended with the enediyne diamine (Z)-octa-4-en-2,6-diyne-1,8-diamine that is capable of photothermally generating 1,4-diradical species under visible excitation (λ = 514 nm, 100 mW, 2–6 h). In the absence of biopolymer substrate, photothermal excitation of these particles leads to self-quenching polymer coating formation in water. When these radical-generating nanoparticles are intrinsically applied toward the blood clot structural protein assembly fibrin, as well as its nonpolymerized precursor protein fibrinogen, scanning electron microscopy images reveal significantly modified fibrin clot morphology, as evidenced by larger void spaces and collapsed fiber regi...
Hemagglutination, Adherence, and Surface Properties of Vaginal Lactobacillus Species

To address the poorly understood mechanisms through which lactobacilli adhere to vaginal epithelial cells (VECs), 65 wild type lactobacilli isolated from the vaginal flora of young women and 3 American Type Culture Collection Lactobacillus strains were studied. Group I isolates (n = 56) hemagglutinated sheep, rabbit, and human red blood cells (RBCs) and adhered poorly to VECs. In contrast, all 4 group II strains hemagglutinated sheep and human but not rabbit RBCs, adhered in large numbers to VECs, and were identical in five phenotypic tests and DNA-DNA hybridization. Eight other strains (group III) hemagglutinated all RBC types studied, adhered avidly to VECs, and had identical protein and hybridization patterns but showed heterogeneous enzyme activities. Although most wild type lactobacilli from the vaginal flora of young women adhered poorly to VECs, selected isolates (groups II and III) adhered in large numbers, demonstrated specific and reproducible hemagglutination patterns, and may have specific mechanisms of attachment to VECs.
Low-Thermal-Budget Photonic Processing of Highly Conductive Cu Interconnects Based on CuO Nanoinks: Potential for Flexible Printed Electronics.

In the developing field of printed electronics, nanoparticle based inks such as CuO show great promise as a low-cost alternative to other metal-based counterparts (e.g., silver). In particular, CuO inks significantly eliminate the issue of particle oxidation before and during the sintering process that is prevalent in Cu-based formulations. We report here the scalable and low-thermal-budget photonic fabrication of Cu interconnects employing a roll-to-roll (R2R)-compatible pulse-thermal-processing (PTP) technique that enables phase reduction and subsequent sintering of ink-jet-printed CuO patterns onto flexible polymer templates. Detailed investigations of curing and sintering conditions were performed to understand the impact of PTP system conditions on the electrical performance of the Cu patterns. Specifically, the impact of energy and power of photonic pulses on print conductivity was systematically studied by varying the following key processing parameters: pulse intensity, duration, and sequence. Thr...
Gender and Private Security in Global Politics

This timely collection brings together an excellent group of emerging and established scholars engaged in ‘critical gender studies in private security' (p. 2). Hailing from a variety of disciplines...
Color multi-fusion fisher vector feature for fine art painting categorization and influence analysis

This paper presents a novel set of image features that encode the local, color, spatial, relative intensity information and gradient orientation of the painting image for painting artist classification, style classification as well as artist and style influence analysis. In particular, a new color DAISY Fisher vector (CD-FV) feature is first created by computing Fisher vectors on densely sampled DAISY features. Second, a color WLD-SIFT Fisher vector (CWS-FV) feature is developed by fusing Weber local descriptors (WLD) with Scale Invariant Feature Transform (SIFT) descriptors and Fisher vectors are computed on the fused WLD-SIFT features. Finally, an innovative color multi-fusion Fisher vector (CMFFV) feature is developed by integrating the Principal Component Analysis (PCA) features of CD-FV, CWS-FV and color SIFT-FV features. The effectiveness of the proposed CMFFV feature is assessed on the challenging Painting-91 dataset. Experimental results show that the proposed CMFFV feature is able to (i) achieve the state-of-the-art performance for painting artist classification, (ii) outperform other popular image descriptors, as well as (iii) discover the artist and style influence to understand their connections and evolution in different art movement periods.
Observations on some of the basic concepts of electrocardiography.

Most electrocardiographers do not appear to understand that certain concepts, widely accepted and regarded as basic, are derived from, simplifications of a type more familiar to engineers than to physicians. Consequently beginners are taught technics, the validity of which depends on the applicability of these simplifications to the conditions encountered in the body. An attempt has been made to inquire into a few of these matters as simply as possible.
Corrigendum to "Advances in T-cell therapy for ALL" [Best Pract Res Clin Haematol 27 (2014) 222-228].

The authors regret that an acknowledgement regarding funding was not included in this article. The following paragraph should have been included in the article: Financial support was provided by grants from the National Institutes of Health (R01CA102646 and R01CA116660), the Pennsylvania Department of Health, the Leukemia and Lymphoma Society, and the Jeffrey Jay Weinberg Memorial Foundation. The authors would like to apologise for any inconvenience caused.
Thinking about Schools and Universities as Social Institutions

I was born in Albuquerque, NM in 1951. My father, one of the first computer systems analysts, worked in the defense industry at Sandia Laboratories. My mother raised three boys and acted in local theater. Both of my parents were Jewish, but secular by orientation. Though neither held advanced degrees, they were politically liberal and intellectually oriented. When I told my parents at age 9 that I had no intention to continue with Sunday school, my mother agreed as long as I promised to read an illustrated treatise on the world’s major religions.
Case 34-2016. A 17-Year-Old Boy with Myopia and Craniofacial and Skeletal Abnormalities.

A 17-year-old boy was seen in the medical genetics clinic because of myopia, craniofacial and other skeletal abnormalities, and pectus excavatum. Ophthalmologic examination revealed ectopia lentis, and imaging studies showed osteoporosis. Diagnostic testing was performed.
Long-term outcomes for patients with chronic lymphocytic leukemia who discontinue ibrutinib.

BACKGROUND Ibrutinib is a Bruton tyrosine kinase inhibitor and is approved for the treatment of patients with chronic lymphocytic leukemia (CLL) in frontline and relapsed/refractory settings. The authors previously reported poor outcomes for patients who discontinued ibrutinib; however, long-term outcomes were not reported. METHODS Data from 320 patients who received ibrutinib on clinical studies between 2010 and 2015 at The University of Texas MD Anderson Cancer Center were retrospectively analyzed. RESULTS Long-term outcomes among patients with CLL after they discontinued ibrutinib were analyzed. Ninety of 320 patients (28%) who were treated on ibrutinib-based regimens discontinued ibrutinib. Of these, 80 had relapsed/refractory disease, and 10 were treatment-naive. The median time to discontinuation was 15 months (range, 1.2-54 months). After a median follow-up of 38 months after starting ibrutinib, 40 patients (44%) remained alive. Major reasons for ibrutinib discontinuation were intolerance (n = 29; 32%), miscellaneous (n = 28; 31%), progression (n = 19; 21%), and Richter transformation (RT) (n = 9; 10%). The median survival according to the reason for discontinuation was 33 months for ibrutinib intolerance, 11 months for miscellaneous causes, 16 months for progressive CLL, and 2 months for RT. Among the 19 patients who had progressive CLL, 42% responded to subsequent therapy. CONCLUSIONS Ibrutinib discontinuation was observed during therapy. Patients with CLL who had disease transformation had especially poor outcomes, whereas those who developed progressive disease during ibrutinib therapy had a median survival of <1.5 years. Survival was associated with the reason for discontinuation; patients who had progressive CLL had better survival compared with those who had disease transformation. Effective salvage strategies for patients with CLL who progress on ibrutinib therapy is of critical importance. Cancer 2017;123:2268–2273. © 2017 American Cancer Society.
Control of immune-mediated pathology via the aryl hydrocarbon receptor

Genetic and environmental factors contribute to the development of immune-mediated diseases. Although numerous genetic factors contributing to autoimmunity have been identified in recent years, our knowledge on environmental factors contributing to the pathogenesis of autoimmune diseases and the mechanisms involved is still limited. In this context, the diet, microbiome, geographical location, as well as environmental pollutants have been shown to modulate autoimmune disease development. These environmental factors interact with cellular components of the immune system in distinct and defined ways and can influence immune responses at the transcriptional and protein level. Moreover, endogenous metabolites generated from basic cellular processes such as glycolysis and oxidative phosphorylation also contribute to the shaping of the immune response. In this minireview, we highlight recent progress in our understanding of the modulation of the immune response by the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor whose activity is regulated by small molecules provided by diet, commensal flora, environmental pollutants, and metabolism. We focus on the role of AhR in integrating signals from the diet and the intestinal flora to modulate ongoing inflammation in the central nervous system, and we also discuss the potential therapeutic value of AhR agonists for multiple sclerosis and other autoimmune diseases.
Wayne County Medical Examinerâ€™s Office Homicide in Wayne County: An Epidemic in the Black Community

The mission of the Wayne County Medical Examinerâ€™s Office is to determine the cause and manner of death of those who die in Wayne County under the conditions of Act No.92 of the Michigan Public Acts of 1969 (Medical Examinerâ€™s Office).Â In Wayne County, five manners of death are recognized: Accident, Homicide, Indeterminate, Natural and Suicide (Medical Examinerâ€™s Office). This article will specifically discuss prevalence of homicide cases at WCMEO and the implications of these deaths for Wayne County and the African-American community. As a social work intern, one of the main objectives of the pilot program was to provide support for the families of the decedents. A large majority of the families supported were African-Americans who had lost their loved one due to a homicide. There are a disproportionate number of black males that are victims of homicide in Wayne County. This is a systemic problem and a social justice issue. There is limited research or data available around recent statistics of homicide in the black community, the effect of homicide in the black community, the implications of homicide for the surviving family members, support for surviving homicide family members and a national model for treatment or trauma associated with these losses.
Engaging Diasporas in Development: Contours and Outcomes of International Policymaking

Over the past decade, diasporas as transnational agents have figured prominently on the agenda of a number of global as well as regional initiatives, processes, and forums devoted to exploring the migration–development nexus. This intense consultative activity stems from the increased realization of the role and positive impact diaspora communities could have on both sending and host countries’ development. The chapter takes the measure of this multilayer policymaking activity. It focuses on the contours and outcomes of the United Nations Global Commission on International Migration (GCIM), the High-Level Dialogue on Migration, and the Global Forum on Migration and Development. It also discusses key policy developments at the interregional (AU-EU) and regional (AU) levels centered around a set of four strategic policies that call on governments to identify their goals and capacities in relation to the diaspora, to know their diaspora, to build trust with the diaspora, and to implement targeted measures aimed at effectively mobilizing the diaspora for development.
Test-based promotion policies, dropping out, and juvenile crime

Abstract Over the past decade, several states and school districts have implemented accountability systems that require students to demonstrate a minimum level of proficiency through standardized tests. With many states and school districts ending social promotion, policy makers and researchers have gained renewed interest in the role of grade retention and remedial education in US schools. This paper examines the potential effects of summer school and grade retention on high school completion and juvenile crime. To do so, we use administrative data from a number of state agencies in Louisiana and a regression discontinuity design to analyze Louisiana's statewide test-based promotion policy administered to students in fourth and eighth grades. Our results indicate that potential grade retention increases the propensity of a student to drop out of school. In addition, eighth grade remedial education assignment in the form of summer school appears to provide a positive benefit by decreasing the likelihood that a student drops out. As for fourth grade students, however, we do not find any effect of summer school assignment. Finally, for eighth graders, we find that the net effect of the test-based promotion policies is to decrease the probability of being convicted of a juvenile crime.
Molecular identification of Bathymaster spp. (Bathymasteridae) larvae in the Gulf of Alaska and eastern Bering Sea

Information on the phenology and distribution of fish larvae is critical to understanding recruitment dynamics of populations. Larvae of the family Bathymasteridae (ronquils) are an abundant component of the ichthyoplankton community in the eastern North Pacific Ocean and Bering Sea, but cannot be readily identified to the species level using morphological or meristic approaches. We developed a restriction fragment length polymorphism (RFLP) protocol based upon variation in the mitochondrial (COI) gene to identify larvae of three species in the genus Bathymaster: smallmouth ronquil (B. leurolepis), Alaskan ronquil (B. caeruleofasciatus) and searcher (B. signatus). A subsample of larvae from annual ichthyoplankton surveys was screened using the RFLP protocol, and 259 of 260 individuals were correctly identified to species, providing the first data on the seasonal occurrence of early life-history stages in ichthyoplankton surveys for these species. Peak abundance for two species in surveys conducted from 2006 to 2014 occurred in spring. Larvae of smallmouth ronquil were absent from spring surveys and occurred as only 8% of the total numbers collected in later seasons. Our results indicate that larvae of Alaskan ronquil (B. caeruleofasciatus) were more likely to occur at deeper sampling stations (bottom depth > 180 m) in spring, while searcher (B. signatus) larvae were more common at shallower stations (bottom depth ≤ 100 m).
Percutaneous Management of a Pyocystic Fistulizing Continent Urinary Diversion.

Abstract Background: Continent diversions have since been performed with increasing frequency since the 1950s, with some providers espousing the use of orthotopic diversions as being the new gold standard. However, patients must be counseled to take great care in the maintenance of their diversions because of complications such as metabolic abnormalities, pouch stones, and mucus retention. Case Report: A 21-year-old male with a history of posterior urethral valves underwent a continent catheterizable diversion as a child. He is undocumented and without health insurance and as a result unable to follow-up with an urologist for >10 years. He subsequently develops pyocystis with cutaneous fistulization and pouch stones necessitating percutaneous management. Conclusion: Patients may benefit greatly from a continent urinary diversion, however, selection must include patients who are able to maintain their pouch and follow-up with their providers to avoid major complications that may occur up to years following...
Time series analysis of soybean response to varying atmospheric conditions for precision agriculture

Four time-lapse cameras, Bushnell Nature View HD Camera (Bushnell, Overland Park, KS, USA) were installed in a soybean field to track the response of soybean plants to changing weather conditions. The purpose was to confirm if visible spectroscopy can provide useful data for tracking the condition of crops and, if so, whether game and trail time-lapse cameras can serve as reliable crop sensing and monitoring devices. Using the installed cameras, images were taken at 30-min intervals between July 22 and August 1, 2015. Using the RGBExcel software application developed in-house, image data from the R (red), G (green), and B (blue) bands were exported to Microsoft Excel for further processing and analysis. Daytime adjusted green red index data for the plant, based on the R and G data, were plotted against time of image acquisition and also regressed with selected weather parameters. The former showed a rise-and-fall trend with daily peaks around 13:00, while the latter showed a decreasing order of correlation with weather variables as follows: log of solar radiation > log of soil surface temperature > log of air temperature > log of soil temperature at 50-mm depth > log of relative humidity. Despite some low correlations, the potential for using game and trail cameras with time-lapse capability to track changes in crop vegetation response under varying conditions is established. The resulting data can be used to develop models that can aid precision agriculture applications. This can be further explored in future studies.
Diagnosis of dementia in cancer patients: Cognitive impairment in these patients can go unrecognized

Abstract Among 61 cancer patients referred for neuropsychiatric consultation, 43 (71%) had an organic mental disorder, and in 11 patients the disorder was consistent with dementia. Three of these cases are described in some detail to discuss the possible etiology of the organic mental disorder and to stress the importance of understanding the neurotoxic effects of chemotherapeutic agents.
In the Realm of Ideas: the Advent of Advanced Surgery of the Human Cerebrum and Neurosurgical Education

High technology has recently exerted remarkable positive forces within the field of neurological surgery. Striking developments in brain imaging, stereotaxy, molecular biology, radiation physics and complex data management promise to revolutionize surgery of the human cerebrum. These changes are not without profound impact on national health care economics and present enormous philosophical and educational challenges which will create considerable turmoil over the next decades.
Questioning the Effectiveness of Addiction Treatments

Some of the most significant economic and social problems facing society are associated with alcohol and drug dependence (National Institute on Drug Abuse, 1991; Merril, 1993). In the United States alone, it has been estimated that alcohol abuse costs approximately $90 billion and that abuse of other drugs costs approximately $67 billion each year (Rice, Kellman, and Miller, 1991). In terms of public health and safety, many studies have shown that one fifth to one fourth of all deaths annually are associated in some way with alcohol, drug or tobacco use (Horgan, 1994). Finally, the social deterioration associated with substance abuse is illustrated by the fact that more than three-fourths of all foster children in the U.S. are the offspring of alcohol and/or drug dependent parents (Childrens Defense Fund Report, 1994).
Online Certificate Status Checking in Financial Transactions: The Case for Re-issuance

High-value financial transactions underwrite the need for a relying party to check the status of a digital certificate in real time. In this paper, we propose a simple mechanism for online certificate status checking that is particularly well suited to the closed public key infrastructures that characterize financial networks. We further demonstrate how persistent evidence of this status checking request/response becomes a valuable by-product. In financial systems, "transaction receipts" naturally accumulate and by doing so, they encapsulate the entire lifecycle of a single transaction.
A Cascaded Self-Similar Rat-Race Hybrid Coupler Architecture and its Compact Fully Integrated Ka-band Implementation

This paper presents a cascaded rat-race coupler architecture that performs broadband in-phase and differential signal generation while maintaining a very compact passive structure size. Our proposed cascaded coupler can support multiband multi-standard 5G communication systems at 24, 27, 37, 39GHz. We have demonstrated that the cascade topology successfully suppresses the output amplitude mismatch and maintains differential output phases, enabling substantial coupler bandwidth extension. A proof-of-concept 22.6-43.4 GHz 2nd-order cascaded rat-race coupler is implemented in the GlobalFoundries 45nm CMOS SOI process. Based on our measurement results, the cascaded rat-race coupler design achieves a less than 5° phase error, less-than 1dB magnitude mismatch, an average insertion loss of only 2.5dB, and better-than −10dB input matching across the entire Ka-band.
Raising Them Right: AI and the Internet of Big Things

Abstract Artificial intelligence (AI) systems tend to grow more capable by increasing in size and complexity. With their workings in many cases already difficult to comprehend, this points to an important tradeoff: if we want really useful AI we may have to forego a detailed understanding of how it works in at least some cases. A really useful Internet of Everything (IoE), in turn, requires really useful AI. So, as we embed that AI into the IoE, and, in particular, into the intelligent infrastructure that will make up what I term the “Internet of Big Things,” we are creating a global operating system that is in an important sense opaque. To cope with this, we will have to accept a relationship with the smart things around us that is more akin to that of a parent with its child than to that of a user with its device.
Effect of medication reconciliation interventions on outcomes: A systematic overview of systematic reviews

Purpose To evaluate and summarize published evidence from systematic reviews examining medication reconciliation. Methods MEDLINE, the Cochrane Database of Systematic Reviews, and the Database of Abstracts of Reviews of Effects were searched for English-language systematic reviews published from January 2004 to March 2019. Reviewers independently extracted information and scored review quality using the Assessment of Multiple Systematic Reviews (AMSTAR) tool. For reviews with AMSTAR scores above 7, Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was applied to assess evidence quality, with evidence summarized and conclusions compared across reviews. Results Eleven reviews met the inclusion criteria, 5 of which used meta-analytic pooling. Most systematic reviews included primary studies of comprehensive bundled interventions that featured medication reconciliation as a central component. Reviews largely focused on transitions into and out of hospital settings. Five reviews focused exclusively on pharmacist-led interventions. Of the 5 reviews that considered all types of medication discrepancies, 3 reviews found very low-quality evidence that interventions reduced medication discrepancies. Neither of the 2 reviews that examined clinically significant medication discrepancies found any intervention effect. Of the 5 reviews that examined healthcare utilization outcomes, only 1 found any intervention effect, and that finding was based on low- to very low-quality evidence. Four reviews considered clinical outcomes, but none found any intervention effect. Conclusion An overview of systematic reviews of medication reconciliation interventions found 9 high-quality systematic reviews. A minority of those reviews' conclusions were consistent with medication reconciliation alone having a measurable impact, and such conclusions were almost all based on very low-quality evidence.
Incidence of an Emotional Tax: The Case of Calorie Menu Labeling

Traditionally, information has been assumed to never harm consumers, a notion recently challenged. Salience nudges have been argued to evoke negative emotions, therefore acting as “emotional taxes.” We analyze the emotional and short-term consumer welfare impact of a calorie salience nudge (calorie menu labeling) – a policy implemented nationwide in the U.S. in 2018. To do so, we design a hypothetical restaurant meal experiment. We find a calorie salience nudge may act as an emotional tax, but only for some – there is considerable heterogeneity in the emotional response to the nudge. In particular, we find the nudge emotionally taxes people with low eating self-control, while it emotionally subsidizes those with higher levels of eating self-control. We also find people with lower level of self-control may experience less of benefits from the nudge – the nudge causes them to adjust their high calorie meal consumption by less than do those with higher self-control. Unsurprising, we therefore find that consumers with lower self-control attach a lower (negative) short-term value to the calorie salience nudge. Overall, we find the calorie salience nudge positively impacts consumer welfare, although heterogeneity over consumers is substantial – the consumer value ranges from positive to negative. We find no distributional effects over income from the calorie salience nudge.
Revealing asymmetric spillover effects in hazelnut, gasoline, and exchange rate markets in Turkey: The VECM-BEKK MGARCH Approach

The study used the VECM–BEKK–MGARCH method to model the volatility transmission between the markets of gasoline, exchange rates, and the hazelnut market for the period of 21.07.2005-20.3.2018. The suitability of the VECM–BEKK–MGARCH method was confirmed by statistical testing. The changes in hazelnut prices were not affected by the changes in the prices or final values in the other two sectors (Granger causality). Moreover, the Granger causality tests revealed that, while the change in the gasoline market was not affected by the other two markets, the change in the exchange rates market was affected by the other two markets. Furthermore, especially the volatilities (long–term uncertainties) of the markets were affected by both their own short– and long–term volatilities and other sectors’ short– and long–term volatilities. It was shown that the long–term swings in these three markets were affected by the cross-interaction in the markets. Additionally, as opposed to the case in the positive news, it was observed that pieces of negative news about the markets affected the markets. Keywords: Exchange Rate, Energy Market, Hazelnut Market, Turkey, VECM–BEKK–MARCH.JEL: Q11, Q13, Q14, G17, G18 .
School Staff and Youth Perspectives of Tier 1 Restorative Practices Classroom Circles

This case study describes the experiences and perceptions of school staff and students participating in restorative practices (RP) community building circles during the first year of school-wide RP...
Editorial [1/2]

“Il futuro e gia qui. Solo che non e distribuito in modo molto equo.” William Gibson Questo numero di Ardeth e cominciato in un tempo di viaggi, incontri pubblici, e nel mezzo di una crescente crisi residenziale, allorche abbiamo chiesto agli autori di riflettere sui loro temi di ricerca attraverso la lente della contingenza. La produzione del numero si chiude in tempi di contingenza, quando niente puo offrire certezza e la contingenza, piuttosto che una lente, e nell’aria che respiriamo quot...
Many Labs 5: Registered Replication of Albarracín et al. (2008), Experiment 7:

Albarracin et al. (2008, Experiment 7) tested whether priming action or inaction goals (vs. no goal) and then satisfying those goals (vs. not satisfying them) would be associated with subsequent co...
Maculopapular eruptions and vesicles on the limbs and buttocks.

A 3 year old girl presented to the dermatology department with three days of a progressively worsening rash and swelling of the extremities, and two days of a persisting fever of around 38.1°C. Initially her hands were swollen and itchy, then dome-shaped maculopapular eruptions developed and rapidly progressed to involve both elbows (fig 1). She also had multiple erythematous papules on the lower limbs and buttocks, and vesicles were present across the buttocks and ankles (fig 2). A few vesicles with crusting were also seen on her upper and lower lips. Fig 1 Multiple dome-shaped maculopapular eruptions on hands Fig 2 Scattered vesicles on the buttocks She had a mild non-productive cough, malaise, and an …
Music and Metamorphosis in Graeco-Roman Thought

Where does music come from? What kind of agency does a song have? What is at the root of musical pleasure? Can music die? These are some of the questions the Greeks and the Romans asked about music, song, and the soundscape within which they lived, and that this book examines. Focusing on mythical narratives of metamorphosis, it investigates the aesthetic and ontological questions raised by fantastic stories of musical origins. Each chapter opens with an ancient text devoted to a musical metamorphosis (of a girl into a bird, a nymph into an echo, men into cicadas, etc.) and reads that text as a meditation on an aesthetic and ontological question, in dialogue with 'contemporary' debates – contemporary with debates in the Greco-Roman culture that gave rise to the story, and with modern debates in the posthumanities about what it means to be a human animal enmeshed in a musicking environment.
Differential expression of Septin 9 isoforms in cells sensitive and resistant to microtubule stabilizing drugs.

1981 Septin 9 (Sept9) is a microtubule associated protein whose function in normal and cancer cells remains largely unknown. Our previous comparative cytogenetic analysis of Sept9 demonstrated that its locus was amplified in the form of double minute chromosomes and that it was overexpressed in mouse mammary tumors. The Sept9 locus is also amplified in human breast and ovarian tumors. These findings indicate that Sept9 is a putative oncogene. Sept9 is expressed as multiple isoforms that may result from alternative splicing of its mRNA. Based on the ability of Sept9 to bind microtubules and microfilaments, and the genomic amplification observed in cancer cells, we hypothesized that Sept9 might play a role in drug resistance. In particular, Sept9 could be involved in resistance to microtubule interacting drugs, such as Taxol that is used in the treatment of ovarian and breast cancers. Genomic and proteomic analyses on two pairs of Taxol-sensitive and -resistant human cell lines were performed. Using bi-dimensional gel electrophoresis and Western blotting, we found that the complex patterns of Sept9 isoform expression were significantly altered in the resistant cell lines when compared to their sensitive counterparts. The two resistant cell lines displayed almost superimposable patterns of Sept9 expression, despite their selection with two different microtubule-stabilizing agents and their different tissue origin (A540.EpoB40 selected with epothilone B, non-small lung carcinoma and MDA-MB-231.K20T, selected with Taxol, breast carcinoma). FISH analyses indicated no copy number gain compared to the ploidy of the cells. Because we did not detect any significant difference in total Sept9 expression levels in the resistant vs sensitive cells, differential expression of isoforms may have a role in the resistance phenotype. We are currently investigating, at the transcriptional and post-transcriptional levels, how these alterations occurred and if they alter sensitivity to Taxol. Based on a detailed bioinformatic examination of the Sept9 genomic locus, we identified stretches of high density CG di-nucleotides, that mapped at isoform transcription start sites, which could undergo cytosine methylation. Pyrosequencing analysis is being performed to precisely quantify differential levels of methylation in sensitive vs resistant cell lines. Identification by mass spectrometry of Sept9 isoforms expressed in these cells is ongoing. Our findings identify a novel candidate, Sept9, that may be involved in mechanisms of drug resistance and suggest that epigenetic mechanisms could regulate isoform expression in cancer resistant cells. These experiments will reveal critical insights into the regulation of Sept9 isoform expression and its role in cancer development and drug resistance.