Antiviral Therapy for Influenza Infections

1. Karin Hillenbrand, MD 1. Brody School of Medicine East Carolina University Greenville, NC Influenza. American Academy of Pediatrics. In: Pickering LK, ed. 2000 Red Book: Report of the Committee on Infectious Diseases. 26th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 2003:382– 390 Reduction of the Influenza Burden in Children. Committee on Infectious Diseases. American Academy of Pediatrics. Pediatrics. 2002;110 :1246– 1252[OpenUrl][1][Abstract/FREE Full Text][2] Influenza Diagnosis and Treatment in Children: A Review of Studies on Clinically Useful Tests and Antiviral Treatment for Influenza. Ukeyi TM. Pediatr Infect Dis J. 2003;22 :164– 177[OpenUrl][3][CrossRef][4][PubMed][5][Web of Science][6] Influenza infection results in significant morbidity each year for children in the United States. Although usually a self-limited illness, influenza may result in complications, including pneumonia, Reye syndrome, myositis, febrile seizures, and acute encephalopathy. Hospitalization, severe disease, and disease complications are more likely in children younger than 2 years of age and in those who have risk factors, including asthma or other chronic pulmonary disease, significant cardiac disease, immunocompromising conditions, chronic renal disease, hemoglobinopathies, and metabolic diseases, such as diabetes mellitus. The risk of influenza infection can be reduced significantly by annual administration of influenza vaccine, which is recommended for high-risk children and their contacts and for all children younger than 2 years of age. Although not a substitute for vaccination, antiviral agents are … [1]: {openurl}?query=rft.jtitle%253DPediatrics%26rft.stitle%253DPediatrics%26rft.issn%253D0031-4005%26rft.aulast%253DCommittee%2Bon%2BInfectious%2BDiseases%26rft.auinit1%253D%2B%26rft.volume%253D110%26rft.issue%253D6%26rft.spage%253D1246%26rft.epage%253D1252%26rft.atitle%253DReduction%2Bof%2Bthe%2BInfluenza%2BBurden%2Bin%2BChildren%26rft_id%253Dinfo%253Adoi%252F10.1542%252Fpeds.110.6.1246%26rft_id%253Dinfo%253Apmid%252F12456926%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/ijlink?linkType=ABST&journalCode=pediatrics&resid=110/6/1246&atom=%2Fpedsinreview%2F26%2F11%2F427.atom [3]: {openurl}?query=rft.jtitle%253DThe%2BPediatric%2Binfectious%2Bdisease%2Bjournal%26rft.stitle%253DPediatr%2BInfect%2BDis%2BJ%26rft.aulast%253DUyeki%26rft.auinit1%253DT.%2BM.%26rft.volume%253D22%26rft.issue%253D2%26rft.spage%253D164%26rft.epage%253D177%26rft.atitle%253DInfluenza%2Bdiagnosis%2Band%2Btreatment%2Bin%2Bchildren%253A%2Ba%2Breview%2Bof%2Bstudies%2Bon%2Bclinically%2Buseful%2Btests%2Band%2Bantiviral%2Btreatment%2Bfor%2Binfluenza.%26rft_id%253Dinfo%253Adoi%252F10.1097%252F00006454-200302000-00015%26rft_id%253Dinfo%253Apmid%252F12586981%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [4]: /lookup/external-ref?access_num=10.1097/00006454-200302000-00015&link_type=DOI [5]: /lookup/external-ref?access_num=12586981&link_type=MED&atom=%2Fpedsinreview%2F26%2F11%2F427.atom [6]: /lookup/external-ref?access_num=000181062700013&link_type=ISI