The Breast: Comprehensive Management of Benign and Malignant Diseases

Section I: The History of the Therapy of the Breast Disease. The History of the Therapy of Breast Disease. Section Ii: Anatomy and Physiology of the Normal and Lactating Breast. Anatomy of the Breast, Axilla, Chest Wall and Related Metastatic Sites. Breast Physiology: Normal and Abnormal Development and Function. Discharges and Secretions of the Nipple. Section Iii: Benign and Premalignant Lesions. Inflammatory, Infectious & Metabolic Disorders of the Breast. Subareolar Breast Abscess: The Penultimates Stages of the Mammary Duct-Associated Inflammatory Disease Sequence. Gynecomastia. Section Iv: Pathology of Benign and Premalignant Lesions of the Breast. Benign, High-Risk, & Premalignant Lesions of the Breast. Congenital and Acquired Disturbances of Breast Development and Growth. Section V: Clinical Aspects of Benign Disease. Evaluation and Treatment of Benign Breast Disorders. Etiology and Management of Breast Pain. Section Vi: Pathology of Malignant Lesions. In Situ Carcinomas of the Breast: Ductal Carcinoma in Situ, Paget's Disease, Lobular Carcinoma in Situ. Malignant Neoplasia of the Breast: Infiltrating Carcinomas. Extent and Multicentricity of in Situ and Invasive Carcinoma. Mammary Sarcoma and Lymphoma. Epithelia Neoplasms and Dermatological Disorders. Section Vii: Natural History, Epidemiology, Genetics and Syndromes of Breast Cancer. Epidemiology of Breast Cancer. Primary Prevention of Breast Cancer. Breast Cancer Genetics: Heterogeneity, Molecular Genetics, Syndrome Diagnosis, And Genetic Counselling. Patterns of Recurrence in Breast Cancer. Section Viii: Staging of Breast Cancer. Assessment and Designation of Breast Cancer Stage. Section Ix: Prognostic Factors for Breast Cancer. Traditional Prognostic Factors in Breast Cancer. Risk Factors for Breast Carcinoma in Women with Proliferative Breast Disease. Integration of Molecular Biology as Prognostic Parameters for Breast Carcinoma. Steroid and Peptide Hormone Receptors: Methods, Quality Control and Clinical Use. Section X: Molecular Biology of Breast Carcinogenesis and Metastasis. Oncogenes in Human Breast Cancer. Growth Regulation of Normal and Malignant Breast Epithelium. Concepts and Mechanisms of Breast Cancer Metastasis. Gene Therapy of Breast Cancer. Angiogenesis of Breast Cancer. Immunology and the Role of Immunotherapy in Breast Cancer. Section Xi: Screening and Diagnosis of Breast Disease. Examination Techniques: Roles of the Physician and Patient in Evaluating Breast Diseases. Screening and Detection. Interval Breast Cancer and the Kinetics of Neoplastic Growth. Breast Imaging. Stereotactic Imaging and Breast Biopsy. Cytological Needle Samplings of the Breast: Techniques and End Results. Section Xii: Clinical Trials: Biostatistical Applications. Design and Conduct of Clinical Trials for Breast Cancer. Section Xiii: Surgery for Benign and Malignant Diseases of the Breast. Evolution of Surgical Principles and Techniques for the Management of Breast Cancer. Indications and Techniques for Biopsy. General Principles of Mastectomy: Evaluation and Therapeutic Options. Halsted Radical Mastectomy. Extended Radical Mastectomy. Modified Radical Mastectomy and Total (Simple) Mastectomy. Quadrantectomy. Lumpectomy (Segmental Mastectomy) and Axillary Dissection. Extended Simple Mastectomy. Therapeutic Value of Axillary Lymph Node. Section Xiv: Breast Reconstruction and Regional Disease. Breast Reconstruction Following Mastectomy. Section Xv: Complications of Breast Surgery. Wound Care. Lymphedema in the Postmastectomy Patient: Pathophysiology, Prevention and Management. Section Xvi: Current Concepts and Management of Early Breast Carcinoma. Current Concepts on the Biology and Management of in Situ (Tis, Stage 0) Breast Carcinoma. Ductal Carcinoma in Situ: Controversial Issues. Small Invasive Carcinomas: The Role of Axillary Lymph Node Dissection. Selective Management of Axilla in Minimally Invasive and Early Invasive Ductal Carcinoma. Lymphatic Mapping and Sentinel Lymphadenectomy for Breast Cancer. Intraoperative Cytologic Evaluation of Surgical Margins in Breast Cancer. Intraoperative Imprint Cytology. Section Xvii: Surgical Management of Stages I & Ii Breast Cancer. Choice of Operations for Early Breast Cancer: An Expanding Role for Breast Conservation Instead of Mastectomy. Section Xviii: Radiation Therapy for Stages I & Ii Breast Cancer. Adjuvant Radiation Therapy for Primary Management of Apparently Regionally Confined Breast Cancer. Adjuvant Radiation Therapy After Modified Radical Mastectomy. Conservative Surgery and Radiation for Stages I and Ii Breast Cancer. Conservation Surgery and Radiation: The M.D. Anderson Cancer Center Experience. Patterns of Failure in Small Breast Cancers Treated By Conservative Surgery and Radiotherapy at the Institute Gustave-Roussy. Conservation Surgery and Irradiation in Stages I and Ii Disease: The European Experience. Section Xix: Adjuvant Systemic Modalities for Therapy of Stages I and Ii Breast Cancer. Adjuvant Systemic Therapy of Breast Cancer. Section Xx: Management of Advanced Local and Regional Disease. Surgical Procedures for Advanced Local and Regional Malignancies of the Breast. Management of Local/Regional Recurrence: Role of Radiation Oncology and Complications of Mastectomy. Locally Advanced Breast Cancer: Role of Medical Oncology. Section Xxi: Management of Systemic Disease. Detection of Occult Micrometastatic Disease. Palliative Radiotherapy for Disseminated Breast Cancer. Chemotherapy for Metastatic Breast Cancer. Endocrine Therapy of Breast Cancer. Management of Osseous Metastases and Impending Pathological Fractures. Management of Pleural Metastases in Breast Cancer. Management of Central Nervous System Metastases in Breast Cancer. Management of Pericardial Metastases in Breast Cancer. Section Xxii: Special Presentations of Breast Cancer. Bilateral Breast Cancer. Cancer of the Male Breast. Local Recurrence, The Augmented Breast, And the Contralateral Breast. Carcinoma of the Breast in Pregnancy and Lactation. The Unknown Primary Presenting with Axillary Lymphadenopathy. Management of the Patient at High Risk. Section Xxiii: Follow-Up Care and Rehabilitation of the Breast Cancer Patient. General Considerations for Follow-Up. Hormone Replacement Therapy and the Risk of Breast Cancer. Breast Cancer: Nursing Management Issues. Rehabilitation. Dietary Management in Breast Disease. The Psychosocial Consequences of Breast Cancer. Psychosocial Resources for Breast Cancer Patients and Their Families. Patient and Family Resources. Section Xxiv: Medical and Legal Issues Specific to the Care of Breast Cancer. Breast Cancer: A Model for Cancer Education. Legal Issues in Breast Disease. The Delayed Diagnosis of Symptomatic Breast Cancer.