cssi/SciSciGPT-SciSciNet huggingface dataset:
(p, n) reaction for 89<A<130 and an anomalous optical model potential for sub-Coulomb protons

The ($p$,$n$) cross sections were measured from about 2.5 to 5.8 MeV with about 100-keV target resolution for natural Pd, Ag, Cd, In, and Te and for $^{89}\mathrm{Y}$, $^{93}\mathrm{Nb}$, $^{103}\mathrm{Rh}$, $^{105,106,108,110}\mathrm{Pd}$, $^{107,109}\mathrm{Ag}$, $^{111,112,113,114,116}\mathrm{Cd}$, and $^{125,126,128,130}\mathrm{Te}$. Systematic uncertainties are about \ifmmode\pm\else\textpm\fi{}2% for $^{89}\mathrm{Y}$, $^{93}\mathrm{Nb}$, and the natural targets and about \ifmmode\pm\else\textpm\fi{}4% for the other nuclei. The isotopic ${\ensuremath{\sigma}}_{p,n}$ are fitted by adjustment in the depth ${W}_{D}$ and diffuseness ${a}_{D}$ of the surface imaginary part of a proton optical model potential (OMP) that was chosen previously to describe precision ($p$,$n$) data for isotopes of Sn. The diffuseness ${a}_{D}$ is found to be nearly constant, about 0.4 fm, but the depth ${W}_{D}$ shows a large and systematic $A$ dependence. A study of the parameter space indicates that at least one OMP parameter must have a strong $A$ dependence and that ${W}_{D}$ is probably the only such single parameter that will suffice. The explanation of this anomaly is currently unclear.
Does surgeon workload per day affect outcomes after pulmonary lobectomies

Background Our aim was to evaluate whether the workload of a surgeon, including number of operations, operative time, or number of rooms per day, influenced patient morbidity or mortality after pulmonary lobectomy. Methods The records of all patients who underwent pulmonary lobectomy at our institution during 2 years (2007–2009) by 6 surgeons were retrospectively reviewed. Surgeon workload per day and individual patient variables were evaluated. Both univariate and multivariate analyses were performed to identify risk factors for patient morbidity and mortality. Results We analyzed 481 patients (269 men, 112 women) whose median age was 68 years (range, 20 to 94 years). Operative mortality occurred in 6 patients (1.25%), and morbidity occurred in 198 patients (41%). On univariate analysis, the total number of hours a surgeon operated per day was a significant predictor of complications (odds ratio, 1.032; p = 0. 048) and length of stay (average increase of 0.17 days for each additional hour; p = 0.004). There were multiple patient variables that were significant predictors of outcome. On multivariate analysis, which adjusted for patient variables, the total number of hours a surgeon operated per day remained a significant predictor of complications (odds ratio, 1.036; p = 0.03) and increased length of stay (average increase of 0.16 days for each additional hour; p = 0.006). On multivariate analysis, patient variables of age, forced expiratory volume In 1 second, and renal failure were significant predictors of outcome. Conclusions The total number of hours a surgeon operates per day is independently associated with an increased risk of complications when performing pulmonary lobectomies. This could be related to surgeon fatigue associated with longer operative days. However, other patient variables are also associated with outcome. The relationship among these factors needs to be better understood with larger-scale models on a multiinstitutional level.
Further analysis of the cuticular proteins of the oak silkmoth and other insects

Abstract The protein extracts of the silkmoth Antherea polyphemus cuticles from larval, pupal and adult stages have been analyzed by one and two dimensional electrophoresis. While the larval cuticle consists of mainly low molecular weight acidic proteins, the majority of the pupal cuticular proteins (both wing and abdominal) exhibit sizes in the range of 15–30 kDa and isoelectric points in the range of 6.5–7.5. The adult cuticle is made up of proteins with a wider range of sizes and isoelectric points. The anti-pupal and anti-adult cuticular antibodies cross react with proteins of either stage quite well. The same antibodies do not cross react with the major larval cuticular proteins. The cuticular proteins of another silkmoth Antheraea pernyi and the well-studied tobacco hornworm Manduca sexta have also been analyzed. The electrophoretic gel patterns of the Manduca cuticular proteins and their cross reactivity with the anti-silkmoth cuticular antibodies are shown to be very similar to those seen with the A. polyphemus cuticular proteins. It is possible to distinguish the abdominal cuticular proteins as coming from a particular stage from each of the insects. The gel patterns of the cuticular proteins of the three insects from any one stage of development are much more similar to each other than those of the same insect from different stages. The protein composition of the segmental and intersegmental regions of the pupal abdomen appears similar by electrophoretic analysis.
Assessing Diagnostic Approaches to Depression in Medically Ill Older Adults: How Reliably Can Mental Health Professionals Make Judgments About the Cause of Symptoms?

OBJECTIVE: To evaluate the reliability of the DSM-IV approach and five other schemes for counting symptoms toward the diagnosis of depression in hospitalized medically ill older patients and to examine whether mental health professionals can reliably make judgments about the etiology (medical or psychological) of depressive symptoms. METHOD: A sample of 38 patients aged 60 years or older admitted to the general medicine, cardiology, or neurology services at Duke University Medical Center were evaluated for depression using a structured psychiatric interview and the Hamilton Depression Scale. Interrater reliability for the diagnostic schemes, for unstructured clinical diagnoses, and for determinations of the causes of individual depressive symptoms was assessed by three pairs of mental health professionals. RESULTS: Agreement between raters for structured diagnoses was high regardless of diagnostic strategy, with the DSM-IV approach being only slightly less reliable than the strict inclusive approach (Kappa 0.88 vs Kappa 1.0, respectively). For all diagnostic approaches, there was perfect agreement between raters for eight cases of major depression. Agreement for unstructured clinical diagnoses of depression (K = 0.50) was much lower than for the structured diagnoses. Agreement between raters on the etiology of individual depression criterion symptoms assessed by structured interview was greater than 80% for 14 of 19 symptoms. Correlation between raters' depression severity ratings on the Hamilton Scale using the DSM-IV etiologic approach was equivalent to that using the strict inclusive approach (0.98 vs 0.95, respectively). CONCLUSIONS: Mental health professionals can be trained to make judgments reliably about the cause (medical or psychological) of symptoms in hospitalized older medical patients. The “strict inclusive” and other diagnostic schemes for counting symptoms toward the diagnosis of depression have only marginal, if any, benefit compared with the the current DSM-IV approach.
First-principles study of the structural and electronic properties of Cu clusters.

The structural and electronic properties of small (n\ensuremath{\le}5) Cu clusters are determined from first-principles calculations based on the local-spin-density approximation, using an all-electron, Gaussian-orbital formalism. The computational method includes use of a systematically refined numerical integration mesh, providing extremely accurate total energies and atomic forces, and a variational technique for treating accidental degeneracies at the Fermi level. Equilibrium geometries have been determined for the neutral clusters for n\ensuremath{\le}5, as well as for the ${\mathrm{Cu}}_{2}$ and ${\mathrm{Cu}}_{3}$ anions. The calculated properties of the dimer and trimer structures are examined in detail and compared to existing experimental measurements. The influence of the Cu 3d states on cluster properties is analyzed. It is shown that there is significant hybridization between the 3d and 4s in the cluster bonding states. One effect of this hybridization is a strong bond-length preference in the clusters.
Physiology of Transition from Intrauterine to Extrauterine Life

The transition from fetus to newborn is the most complex adaptation that occurs in human experience. Lung adaptation requires coordinated clearance of fetal lung fluid, surfactant secretion, and onset of consistent breathing. The cardiovascular response requires striking changes in blood flow, pressures, and pulmonary vasodilation. Energy metabolism and thermoregulation must be quickly controlled. The primary mediators that prepare the fetus for birth and support the multiorgan transition are cortisol and catecholamine. Abnormalities in adaptation are frequently found following preterm birth or cesarean delivery at term, and many of these infants need delivery room resuscitation to assist in this transition.
Autograft Versus Nonirradiated Allograft Tissue for Anterior Cruciate Ligament Reconstruction: A Systematic Review

Background:An autograft has traditionally been the gold standard for anterior cruciate ligament reconstruction (ACLR), but the use of allograft tissue has increased in recent years. While numerous studies have demonstrated that irradiated allografts are associated with increased failure rates, some report excellent results after ACLR with nonirradiated allografts. The purpose of this systematic review was to determine whether the use of nonirradiated allograft tissue is associated with poorer outcomes when compared with autografts.Hypothesis:Patients undergoing ACLR with autografts versus nonirradiated allografts will demonstrate no significant differences in graft failure risk, laxity on postoperative physical examination, or differences in patient-oriented outcome scores.Study Design:Systematic review.Methods:A systematic review was performed to identify prospective or retrospective comparative studies (evidence level 1, 2, or 3) of autografts versus nonirradiated allografts for ACLR. Outcome data inclu...
What can we learn from drug marketing efficiency

The time it takes new drugs to penetrate the market is shrinking. David Kao suggests how drug companies’ techniques could be used to improve safety surveillance systems
The clinical and audiologic features of hearing loss due to mitochondrial mutations.

ObjectivesTo characterize mitochondrial sequence variants present in a nationwide hereditary deafness DNA repository of samples from deaf subjects and to define the clinical presentation and audiometric characteristics of individuals with a mitochondrial sequence variant.Study DesignRetrospective review of results for select mitochondrial mutations performed on DNA samples from subjects compiled from 1997 to 2009.SettingNational hereditary deafness DNA repository.Subjects and MethodsAvailable samples from subjects in the repository were screened to identify those with mitochondrial sequence variants. Clinical data on the nature of mutation, type and severity of the hearing loss, and sex, age at diagnosis, family history of hearing loss, and ethnicity were analyzed.ResultsEighty-six patients were identified with mitochondrial mutations or 3.5% of the subjects studied. Among those with mitochondrial mutations, 21 (24.4%) had the m.7445A>G substitution, 18 (20.9%) had the m.1555A>G substitution, 18 (20.9%) h...
An Ethic of Race for Public Administration

Remarkably little public administration scholarship has explored the dynamic of race as manifest in patterns of policy interpretation and discretionary judgments of individual administrators. We raise the issue of race in public administration despite the widespread view that the lens of race is obsolete or counterproductive. We argue that scholarship in the field has failed to come to terms with how this neglect has contributed to maintaining long-standing policies and practices with racist implications. We explore the question of whether the lens of race reveals the outline of an ethic for administrative practice. After a brief illustrative historical review, we critique the current approaches to incorporating race into administrative practice (managing diversity and cultural competence) as inadequate for the necessary rethinking at the theoretical level. We propose an ethical framework based on American pragmatist philosophy and on Hannah Arendt's notion of inclusive solidarity.
Outcomes of noncardiac surgery after coronary bypass surgery or coronary angioplasty in the Bypass Angioplasty Revascularization Investigation (BARI)

Abstract Purpose: Previous studies have shown that coronary artery bypass surgery reduces the risk of cardiac complications after noncardiac surgery. Whether coronary angioplasty provides equivalent protection is not known. SUBJECTS AND METHODS: Patients were randomly assigned to undergo cardiac artery bypass surgery or angioplasty as part of the Bypass Angioplasty Revascularization Investigation trial. All subsequent noncardiac surgeries during a mean (± SD) follow-up of 7.7 years were recorded among participants in the ancillary Study of Economics and Quality of Life. Rates of mortality and nonfatal myocardial infarction, length of stay, and hospital costs were compared by the original randomized assignment. RESULTS: A total of 501 patients had noncardiac surgery at a median of 29 months after their most recent coronary revascularization procedure. Mortality and nonfatal myocardial infarction within 30 days of the first noncardiac surgery occurred in 4 of the 250 of the surgery-assigned patients and in 4 of the 251 of the angioplasty-assigned patients ( P = 1.0). There were no significant differences in the mean length of hospital stay (6.3 ± 6.7 versus 6.2 ± 6.8 days; P = 0.47) or hospital cost ($8,920 ± $11,511 versus $7,785 ± $7,643; P = 0.33) between the surgery and angioplasty groups. Similar results were obtained when subsequent noncardiac procedures were included in the analysis. CONCLUSION: Rates of myocardial infarction and death after noncardiac surgery are similarly low after contemporary bypass surgery or angioplasty in patients with multivessel coronary artery disease.
Velocity dependence of the free carrier optical absorption constant in polar semiconductors

Abstract The velocity dependence of the free polaron optical absorption constant has been determined on solving the Heisenberg's equations of motion for the polaron. It has been shown that an enhancement of the carrier velocity exhibits two main modifications of the optical absorption line shape: first, a small shift of the absorption threshold towards lower frequencies, second an important increase of the peak intensity.
Gene expression and larval evolution: changing roles of distal-less and orthodenticle in echinoderm larvae.

SUMMARY We describe the expression of the homeobox genes orthodenticle (Otx) and distal-less (Dlx) during the larval development of seven species representing three classes of echinoderms: Holothuroidea, Asteroidea, and Echinoidea. Several expression domains are conserved between species within a single class, including Dlx expression within the brachiolar arms of asteroid larvae and Otx expression within the ciliated bands of holothuroid larvae. Some expression domains are apparently conserved between classes, such as the expression of Dlx within the hydrocoel (left mesocoel) in all three classes. However, several substantial differences in expression domains among taxa were also evident for both genes. Some autapomorphic (unique derived) features of gene expression are phylogenetically associated with autapomorphic structures, such as Dlx expression within the invaginating rudiment of euechinoids. Other autapomorphic gene expression domains are associated with evolutionary shifts in life history from feeding to nonfeeding larval development, such as Otx expression within the ciliated bands of a nonfeeding holothuroid larva. Similar associations between evolutionary changes in morphology and life history mode with changes in regulatory gene expression have also been observed in arthropods, urochordates, and chordates. We predict that recruitment of regulatory genes to a new developmental role is commonly associated with evolutionary changes in morphology and may be particularly common in clades with complex life cycles and diversity of life history modes. Caution should be used when making generalizations about gene expression and function based on a single species, which may not accurately reflect developmental processes and life histories of the phyla to which it belongs.
Improving Phonological Awareness and Decoding Skills of High School Students From Diverse Backgrounds

(2008). Improving Phonological Awareness and Decoding Skills of High School Students From Diverse Backgrounds. Preventing School Failure: Alternative Education for Children and Youth: Vol. 52, No. 2, pp. 67-72.
In Vivo Histamine Optical Nanosensors

In this communication we discuss the development of ionophore based nanosensors for the detection and monitoring of histamine levels in vivo. This approach is based on the use of an amine-reactive, broad spectrum ionophore which is capable of recognizing and binding to histamine. We pair this ionophore with our already established nanosensor platform, and demonstrate in vitro and in vivo monitoring of histamine levels. This approach enables capturing rapid kinetics of histamine after injection, which are more difficult to measure with standard approaches such as blood sampling, especially on small research models. The coupling together of in vivo nanosensors with ionophores such as nonactin provide a way to generate nanosensors for novel targets without the difficult process of designing and synthesizing novel ionophores.
George S. Long, Timber Statesman

When Frederick Weyerhaeuser and his midwestern associates purchased 900,000 acres of western Washington timberland from the Northern Pacific Railway Company in 1900, the initial question was, who would manage the property? Recommended as a valued employee by one of the associates, George S. Long (1853-1930) was hired by Weyerhaeuser on a trial basis. The sheer breadth of Long's responsibility was amazing. Not only was this the largest such purchase in American history, but for the investors that amounted to a giant leap in the dark. They knew next to nothing about the details of their ownership, and Douglas-fir was an unfamiliar species. And where were the markets? Long's first job was to get acquainted with the land, the people, and forestry methods. He soon realized that diplomatic skills would be far more useful in the beginning than would expertise in lumber. The Weyerhaeuser Timber Company was not initially involved in manufacturing, but by the end of Long's career, modern Weyerhaeuser mills were in operation at Everett, Longview, and Snoqualmie Falls in western Washington, and at Klamath Falls, Oregon. Each was a self-sufficient, integrated unit, with enough timber in reserve to maintain operations for a significant period, even without reforestation. But the possibility of reforestation fueled Long's imagination. He recognized that the challenge was to maximize the Pacific Northwest's huge forest-growth capacity - a challenge that continues to this day. Appointed at a time when Frederick Weyerhaeuser was still clearly in charge, Long quickly earned his trust. In a few brief years he had become indispensable. In the Pacific Northwest he was not only "Mr. Weyerhaeuser" but the oneto whom others in the industry looked for leadership. Under his aegis, the Washington Forest Fire Association came into being, soon to be followed by the Western Forestry and Conservation Association. And in the 1920s he led in creating the West Coast Lumbermen's Association. Cha
Comparative study of leadership in divided nations: Past, present and possible futures

(1981). Comparative study of leadership in divided nations: Past, present and possible futures. Journal of East and West Studies: Vol. 10, No. 2, pp. 23-44.
Stock Dynamics and Recreational Fishing Welfare Estimation: Implications for Natural Resource Damage Assessment

From a modeling perspective, the assessment of damages to fisheries resources and welfare analysis of fisheries policy changes have many similarities. Both require information on the dynamics of stock and user group interactions. For damage assessment, beyond measuring how the stock is initially affected, we must know the timing and magnitude of stock growth as the resource recovers. In order to translate these stock changes into changes in resource services, we must quantify the relationship between stock and catch. Evaluating the desirability or efficacy of stock-enhancing fisheries policies requires much of the same information. Another sim-
H and D Atom Addition to Ethylene on Cu(100): Absence of Ethyl H/D Shift and Decomposition

The addition of gas phase H and D atoms to unsaturated hydrocarbons physisorbed on metal surfaces is a viable synthetic route to partially-deuterated alkyl groups on the surface (Jenks, C. J.; Xi, M.; Yang, M. X.; Bent, B. E. J. Phys. Chem. 1994, 98, 2152−2157). Because these processes are exothermic by ∼60 kcal/mol, the possibility of alkyl decomposition and/or rearrangement prior to thermal accommodation with the surface (a possibility not explicitly addressed in prior studies) should be considered. In the studies here, these decomposition and rearrangement possibilities have been investigated by studying H and D atom addition to variously−deuterated ethylenes physisorbed on a Cu(100) surface. Ethyl decomposition by C−H, C−D, or C−C bond scission has been addressed and shown not to occur by comparison with results from previous studies of the surface species that would be formed by these bond scission processes. H/D shift between the two carbons of the ethyl groups has been addressed by heating the surf...
Global gauge anomalies for theories with the Green-Schwarz local-anomaly-cancellation mechanism.

We show that theories with the Green-Schwarz mechanism of canceling local anomalies in even dimensions have the possibility of the worst type of global Yang-Mills chiral anomalies given by the homotopy group of the Yang-Mills gauge group. The examples are given for SU(3) gauge theories in six dimensions ({Pi}{sub 6}(SU(3))={ital Z}{sub 3 }) whose global anomalies are of types {bold Z}{sub 1}, {bold Z}{sub 2}, {bold Z}{sub 3}, and {bold Z}{sub 6}.
Buying supermajorities in a stochastic environment

This paper considers a model in which two opposing lobbyists compete for the votes of legislators, but the precise preferences of the legislators are not known. I show that, in contrast to the normally predicted effect of uncertainty on the formation of supermajorities, in the presence of competing lobbyists, increased risk that members of a lobbyist’s coalition will not vote for the proposal may decrease the number of legislators a lobbyist includes in her coalition.
The Next-Generation Sequencing Revolution and Its Impact on Genomics

Genomics is a relatively new scientific discipline, having DNA sequencing as its core technology. As technology has improved the cost and scale of genome characterization over sequencing's 40-year history, the scope of inquiry has commensurately broadened. Massively parallel sequencing has proven revolutionary, shifting the paradigm of genomics to address biological questions at a genome-wide scale. Sequencing now empowers clinical diagnostics and other aspects of medical care, including disease risk, therapeutic identification, and prenatal testing. This Review explores the current state of genomics in the massively parallel sequencing era.
(Na+ + K+)-ATPase activity in rats with 20, 25-diazacholesterol-induced myotonia.

Abstract 20,25-diazacholesterol, an inhibitor of cholesterol biosynthesis, produces myotonia, but the biochemical correlates of the disease are not completely defined. In rats treated with 20,25-diazacholesterol for 5–6 months the activity of (Na+ + K+)-ATPase in a NaI-extracted high speed fraction of frozen muscle was increased. At this time, desmosterol constituted 70% of the total sterol of this fraction. It is possible that the accumulation of desmosterol was the cause of the increased (Na+ + K+)-ATPase activity. Since 20,25-diazacholesterol produces an experimental myotonia which is very similar to human myotonia, it appears to be an experimental model worthy of further elucidation.
From Monty Python to Total Recall: A feature film activity for the cognitive psychology course

Thirty-nine sophomore and junior college students from an introductory cognitive psychology course participated in a feature film activity designed to help students define the parameters of cognitive psychology, apply course information to nonacademic situations, and work in a cooperative-learning situation. Working in pairs, students selected a feature film and a journal article-that represented some topic in cognitive psychology. Students wrote a three- to five-page paper and gave optional class presentations in which they reported theoretical or empirical connections or both among the cognitive topic, journal article, and film. The instructor and students evaluated the film activity as highly enjoyable, a valuable instructional tool, and a fairly simple task to complete; 85% of the students wrote positive comments about the activity and recommended it be continued in the future.
Percutaneous Transluminal Angioplasty of Venous Anastomotic Stenoses Complicating Liver Transplantation: Intermediate-term Results

Purpose The authors evaluated the safety and efficacy of percutaneous transluminal angioplasty (PTA) for the treatment of venous stenoses in liver transplant recipients. Patients and Methods Over a 5-year period, 15 venous stenoses were treated with PTA in 12 patients with liver transplants (seven children and five adults). PTA was performed for portal vein stenoses in five patients, inferior vena cava (IVC) stenoses ( n = 6) in five patients, combined superior mesenteric vein–portal vein graft anastomosis and hepatic vein–IVC anastomosis in one patient, and combined IVC and hepatic vein–IVC anastomosis in one patient. PTA was repeated in three patients (five procedures) for recurrent IVC stenoses. Results Initial technical and clinical success of PTA was achieved in 11 patients (92%); failure occurred in one patient (8%) with a portal vein anastomotic stenosis. No complications occurred in the immediate post-procedure period (up to 7 days). Nine patients (75%) are clinically well, with follow-up ranging from 7 to 33 months (mean, 18 months). Two of them required one or more repeated PTA procedures to maintain vessel patency. One patient required retransplantation for chronic rejection at 3 months, and another died of gastrointestinal tract bleeding from a gastric ulcer at 2 months after initially successful IVC PTA. Conclusions PTA is a safe procedure for the treatment of venous anastomotic stenoses in liver transplant recipients. PTA of portal vein anastomotic stenosis has favorable intermediate-term results. Repeat PTA may be necessary in some cases of IVC anastomotic stenoses to maintain vessel patency and avoid surgical revision or retransplantation.
Successive laser-induced breakdowns in atmospheric pressure air and premixed ethane-air mixtures

Abstract Two successive focused laser pulses are employed to experimentally simulate laser-induced breakdown plasmas at high repetition rates. We find that energy absorption of the second laser pulse by the plasma produced by the first laser pulse is enhanced slightly when the time interval between the pulses is shorter than several tens of nanoseconds but falls to almost zero when the time interval is between a few hundreds of nanoseconds and several tens of microseconds. This behavior is attributed to gas heating by the first breakdown event. In premixed ethane–air mixtures, we identify another strong reduction in the second laser pulse absorption when this pulse coincides with the heat released by combustion, typically milliseconds after the first laser pulse. The fuel–air equivalence ratio (ϕ) and base flow speed are also varied in this study. The results show that the window of reduced absorption coinciding with heat release due to combustion is narrowed when the base flow speed is increased, and also under fuel lean and fuel rich conditions. These results suggest that the use of pulsed high frequency laser breakdowns for premixed combustion stabilization is optimized when laser pulse repetition rates below a certain frequency (e.g., 500 Hz at the conditions that ϕ is 1 and the base flow speed is 4.9 m/s) to maximize laser energy coupling and for improved anchoring of the flame base.
Parametric approach to variational two-electron reduced-density-matrix theory

Two general variational paradigms for computing ground-state energies and properties of molecular quantum systems are (i) the parametrization of the $N$-particle wave function, as in truncated configuration interaction, which yields an upper bound on the energy in a given basis set and (ii) the constraint of the two-electron reduced-density matrix (2-RDM) by necessary $N$-representability conditions (without using the wave function) which yields a lower bound on the energy in a given basis set [D. A. Mazziotti, Phys. Rev. Lett. 93, 213001 (2004)]. In this paper we synthesize these two directions in a class of techniques which we call parametric variational 2-RDM methods. The 2-RDM in these methods is parametrized to be size consistent while approximately satisfying the $N$-representability conditions. We extend an energy functional of Kollmar [C. Kollmar, J. Chem. Phys. 125, 084108 (2006)], which modifies configuration interaction with double excitations to be size consistent, by including not only double but also single excitations explicitly. Using the 2-RDM parametrization, we calculate ground-state energies at both equilibrium and nonequilibrium geometries in correlation-consistent polarized valance double-zeta (cc-pVDZ) basis sets. Energies as well as properties from the parametric variational 2-RDM method, particularly at nonequilibrium geometries, are better in accuracy than those obtained from coupled cluster with single and double excitations. The present work shows clearly that, except in the dissociation of ${\text{N}}_{2}$, the deviation of the 2-RDM from the well-known $N$-representability conditions, such as the $D$, $Q$, and $G$ conditions, is negligible. Furthermore, calculations with helium atoms demonstrate the size consistency of the method. The computational results on $N$ representability and size consistency are especially important because they legitimatize the selected parametrization of the 2-RDM.
A Note on the Uniform Filling Property and Strong Irreducibility

Various separation properties of shift spaces have been defined in the literature. In Boyle et al. (Trans. Am. Math. Soc. 362:4617, 2010), several were put into a chain of strict implications, leaving one open question: Is the uniform filling property (UFP) a strictly weaker condition than strong irreducibility (SI)? We given an example to show that it is, and we show that UFP and SI are equivalent for two-dimensional square filling shifts of finite type.
Blending Exercise Into Family Life.

(1996). Blending Exercise Into Family Life. The Physician and Sportsmedicine: Vol. 24, No. 2, pp. 83-84.
The development of planning skills in children with and without mental retardation

Abstract This study examines the planning skills of children with and without mental retardation. Thirty-two children, 16 from each group, were compared on their planning strategies, task management, and bids for adult assistance while searching for items in a model grocery store. Children with retardation spent less time visually surveying the store in the course of developing their plans than children without retardation. Also, children with retardation made more item errors and requested more assistance from the experimenter than children without retardation. Age differences in planning skill appeared only for children without retardation, suggesting that the developmental course for these skills may differ between the two populations.
Short-term (90 min) diagnostic performance for acute non-ST segment elevation myocardial infarction and 30-day prognostic evaluation of a novel third-generation high sensitivity troponin I assay.

Abstract Objectives We evaluated a third-generation high sensitivity “guidelines acceptable” troponin I assay (hs-cTnI) against a contemporary “clinically usable” troponin assay (cTnI). Design and methods Remnant samples of undifferentiated emergency department (ED) patients with suspected acute coronary syndrome were enrolled. Baseline and 90-minute samples were analyzed for cTnI and hs-cTnI. Sensitivity, specificity, positive and negative predictive values for AMI and 30-day adverse cardiac events (ACE) were compared. Results Of 486 ED patients, there were 465 patients who had blood remaining at the presentation for the hs-cTnI assays, with 12 AMIs. At presentation, the clinical sensitivity and specificity for AMI was 75% and 97% for cTnI and 83.3 and 82.1% for hs-cTnI. There were 407 patients who had paired baseline and 90-minute blood samples for cTnI and hs-cTnI including 9 of the 12 AMI patients. The sensitivity and specificity was 77.7% and 96.5% for cTnI and 100% and 81.9% for hs-cTnI at 90 min. A Δ change of 30% increase from baseline to 90 min improved the specificity to 94.5% (95% CI 92%–96%) without lowering the sensitivity. When AMI was defined as a Δ30% change of hs-cTnI at t = 0 and 90 min and one hs-cTnI result > 99th percentile cutoff, more than 3 times as many patients met the diagnostic criteria for AMI compared to results from the normal sensitive troponin assay; 28 (6.9%) for hs-cTnI vs. 9 (2.2%) with cTnI. There were 37 in-hospital or 30-day events, producing an OR of 3.03, 95% CI: 0.86–9.59 for cTnI, and 2.54, 95% CI: 1.27–5.10 for hs-cTnI, which detected 11 more cases. Conclusions The hs-cTnI assay achieved a 90-minute rule out for AMI and detected more 3 times as many AMI cases. The specificity increased with the Δ30% criteria. The hs-cTnI assay also detected more cases of patient at risk for adverse cardiac events at 30 days.
An Unexpected Product From Polymerase Chain Reaction-Mediated Site-Directed Mutagenesis Due to Misalignment of the Mismatched Primer.

Background: The I1307K (T3920→A) variant of the APC gene has been identified as a potential risk factor for colorectal cancer and is present in 6% of Ashkenazi Jews. Screening for this mutation may allow identification of people at elevated risk who would benefit from increased surveillance. Methods and Results: We designed an assay to detect the T3920→A allele using a primer mismatched at the 3′ terminal nucleotide in the polymerase chain reaction (PCR) to generate a recognition site for the restriction enzyme Mse I. After optimization of the PCR for magnesium ion concentration and annealing temperature, the amplicon did not cut completely with the restriction enzyme in each of four tested DNAs. Sequence analysis of the PCR product that was resistant to digestion revealed that the T3920→A variant was not present. The artifact was caused by a single nucleotide loop-out in the genomic DNA template under the 3′ region of the primer, which allowed the 3′ terminal base of the primer to hybridize properly. As a result, the mismatched primer created a modified product different from that originally planned. At a magnesium ion concentration below the optimum for product yield, most of the product was digested by Mse I. Sequence analysis showed that, under these conditions, the intended product was produced. Conclusions: Mismatched primers can produce unintended products in a PCR due to looping out of a nucleotide in the template or the primer. The magnesium ion concentration can influence the sequence and amount of the product.
Glucose and l-amino acid electrodes based on enzyme membranes

Abstract Membranes containing immobilized glucose oxidase have been constructed in a simple, easily reproduced procedure. The enzyme is co-crosslinked with bovine serum albumin using the bifunctional agent, glutaraldehyde. Amperometric enzyme electrodes have been constructed using these membranes and the effect of membrane thickness and enzyme activity studied.
Truth-In Publishing: Federal Regulation of the Press's Business Practices 1880-1920

This is the first policy history to examine government regulation of the print media s business practices in the early twentieth century.Most media histories depict the early twentieth-century press as a crusader, working closely with reformers to weed out abuses in society. This book turns the tables and examines the press as a business susceptible to corporate abuses and government regulationjust like any other enterprise. And like other business leaders targeted by reformers, some publishers and advertisers welcomed the scrutiny of reformers and encouraged lawmakers to enact strong legislation to cleanse the profession. Others, however, tried to hide behind the First Amendment and resisted all attempts at government regulation.In the end, Congress bypassed the First Amendment question by linking its regulations to the press s mail privilege, where, it was felt, the courts would uphold its authority to set standards for the subsidy.The Newspaper Publicity Act, passed in 1912, is still in effect and requires commercial newspapers and magazines using the preferential second-class mail rate to identify their owners and investors and to label advertisements that resemble news stories or editorials. Daily newspapers are also required to disclose circulation data along with their ownership statements.In part 1, Lawson documents the press s inner workings, including its excesses and abuses, as it evolved from a collection of small businesses in the mid 1800s to an established commercial institution of the twentieth century. Large, urban newspapers challenged small, rural papers at the same time burgeoning popular magazines and trade journals competed fiercely with every other type of publication for advertisers and readers. The regulatory actions brought about by these divisions within the industry are treated in part 2. Lawson makes clear how Congress, the post office, and the courts responded to the troubling business practices outlined in part 1. Finally, she analyzes what this episode in policy making reveals about the Progressive ideology with its reliance on publicity and regulation to solve social and economic problems and in the process integrates many of the apparently paradoxical strands of scholarship on the Progressive period."
Time-Dependent Ginzburg-Landau Theory of Nonequilibrium Relaxation

The system is considered which is brought into a state far from thermal equilibrium by a sudden change of independent variables. Its approach towards the equilibrium state is studied introducing nonequilibrium relaxation functions. Near the equilibrium state the lowest-order relaxation functions reduce to the time-dependent pair correlation functions. The relaxation process is especially interesting near a first-order phase transition, where metastable states can occur. Characterization of these states in terms of the nonequilibrium relaxation functions is discussed, and a "constructive" definition of the metastable states in terms of a "flatness" property of the relaxation curve is proposed. In order to give explicit results, the time-dependent Ginzburg-Landau theory is treated in detail, and exact solutions for the relaxation functions are given. If an equilibrium state is described by a real-valued order parameter, the inverse lifetime of a metastable state is determined from the imaginary part of its order parameter. Transition from the "metastable" to the stable state is characterized by fluctuations which increase with time for wave vectors up to some critical value, and later decrease again because of the nonlinearity of the Ginzburg-Landau equations. The validity of these results is discussed with respect to systems with long-range interactions, and also a few remarks are given concerning systems with short-range interactions and the nucleation picture.
The effect of acute hypercalcemia on growth hormone release in man.

The growth hormone response to acute hypercalcemia was studied in 9 normal subjects.Growth hormone, calcium, glucose, phosphate and magnesium levels were determined at 30-min intervals during 4-h infusions. Infusions, performed in random order in the subjects, consisted of either normal saline at 3 ml/min for 4 h or 15 mg calcium/kg (calcium gluconate) at 3 ml/min for 3 h followed by normal saline for the fourth hour. Significant hypercalcemia (P < 0.05) was achieved within 60 min and maintained throughout the infusion. No change in calcium concentrations occurred during normal saline infusions, and phosphate, glucose and magnesium were unchanged in all studies. Growth hormone levels were significantly higher (P < 0.05) at 60 min and all subsequent determinations during calcium infusion when compared to normal saline infusions. In 6 of the subjects, standard L-dopa provocative testing with an oral dose of 500 mg was performed during normal saline and calcium infusions identical to those described above. P...
Use of a Modified Tilt Table for Preambulation Strength Training as an Adjunct to Burn Rehabilitation: A Case Series

Because of the system-wide complications that arise with prolonged bed rest, early mobilization plays a critical role in the recovery process, especially in the patient with significant burn injury. Unfortunately, early mobilization of patients with severe burns can be a difficult and uncontrolled task and often requires several people to lift a patient to a standing position. This article describes the use of a modified tilt table that allows patients to perform a weight-bearing exercise, such as an inclined squat, in a gravity-reduced environment. Use of the modified tilt table may offer a more suitable therapeutic option when treating critically ill patients by providing a safe and controlled transition from bed rest to ambulation. Perhaps most importantly, the table appears to provide psychological benefits by empowering the patient to take more of an active role during the early stage of recovery.
The Free Energy Simulation Approach to Grain Boundary Segregation In Cu-Ni

A new, accurate method for determining equilibrium segregation to defects in solids is employed to examine the segregation of Cu to grain boundaries in Cu-Ni alloys. The results are in very good agreement with the ones given by Monte Carlo. This method is based upon a point approximation for the configurational entropy, an Einstein model for vibrational contributions to the free energy. To achieve the equilibrium state of a defect in an alloy the free energy is minimized with respect to atomic coordinates and composition of each site at constant chemical potential. One of the main advantages this new method enjoys over other methods such as Monte Carlo, is the efficiency with which the atomic structure of a defect, segregation and thermodynamic properties can be determined. The grain boundary free energy can either increase or decrease with increasing temperature due to the competition between energetic and configurational entropy terms. In general, the grain boundary free energy increases with temperature when the segregation is strongest.
Primary Cutaneous Immunocytoma Presenting with Diffuse Subclinical Involvement and Demonstrating Kappa and Lambda Light Chain Restrictions

A 37 year-old man with primary cutaneous immunocytoma with lambda light chain restriction involving the left shoulder was treated with Rituxan with clinical resolution. Four years later, he presented with a six-month history of diffuse asymptomatic erythema. Physical examination revealed three grouped papules on the right upper arm and an irregular sclerotic patch with slight erythema superiorly on the left shoulder at the site of the initial tumor. There was no diffuse erythema. Biopsies were obtained from a papule on the right upper arm, the sclerotic patch on the left shoulder, and clinically uninvolved skin on the right anterior thigh. All three specimens showed a variably dense, predominantly periadnexal and perivascular dermal infiltrate of plasma cells and lymphocytes. The specimen from the right arm demonstrated kappa light chain restriction. The specimen from the right thigh showed lambda light chain restriction. Physical examination six weeks later demonstrated mottled erythema on the anterior thighs. Two biopsies were obtained from the right thigh. One showed immunocytoma. The other was unremarkable. The patient's primary cutaneous immunocytoma demonstrated two unusual findings: (1) histologic presence of tumor in clinically uninvolved and minimally involved skin; and (2) the presence of two distinct monoclonal populations.
Relations Among Dimensions of Feminism and Internalized Heterosexism in Lesbians and Bisexual Women

This study was designed to examine the relations among dimensions of feminism and internalized heterosexism in 227 lesbian and bisexual women. In addition, psychometric support for 2 newly created multiple-item scales, Self-Identification as a Feminist (SIF) and Involvement in Feminist Activities Scale (IFAS), is provided. Results indicate that internalized heterosexism is correlated significantly with most of the feminist dimensions assessed in this study (i.e., self-identification as a feminist, involvement in feminist activities, attitudes toward feminism, feminist identity development, and various feminist ideologies). Interesting relations among feminist identity development and feminist ideologies were found. In addition, involvement in feminist activities was uniquely predicted by self-identification as a feminist and the Embeddedness-Emanation and Active Commitment dimensions of feminist identity development. Implications and suggestions for future research are discussed.