cssi/SciSciGPT-SciSciNet huggingface dataset:
Versions of the Apocalypse in Medieval French Verse

During the Middle Ages, the New Testament Apocalypse, or Revelation of St. John, informed a wide variety of literary and artistic works. Besides the forty or so Latin Apocalypse commentaries composed before the thirteenth century, numerous treatises, prognostics, tapestries, picture cycles, vision narratives, and religious dramas drew inspiration or some of their themes from the biblical account. A further manifestation of medieval interest in the Apocalypse was the composition, between c. 1225 and c. 1300, of four distinctive French Apocalypse poems. These poems the illustrated version, the Kerr and Giffard versions, and the Apocalisse of Mace de la Charite -are contained in twelve manuscripts from the thirteenth, fourteenth, and fifteenth centuries.' Each of the versions has been treated separately in studies dating from 1840 to the present.2 However, no attempt has yet been made to examine the versions collectively, comparing their formal and literary aspects, noting their exegetic preoccupations and, in general, tracing the evolution of this medieval subgenre.
Bone-eating Osedax females and their 'harems' of dwarf males are recruited from a common larval pool.

Extreme male dwarfism occurs in Osedax (Annelida: Siboglinidae), marine worms with sessile females that bore into submerged bones. Osedax are hypothesized to use environmental sex determination, in which undifferentiated larvae that settle on bones develop as females, and subsequent larvae that settle on females transform into dwarf males. This study addresses several hypotheses regarding possible recruitment sources for the males: (i) common larval pool — males and females are sampled from a common pool of larvae; (ii) neighbourhood — males are supplied by a limited number of neighbouring females; and (iii) arrhenotoky — males are primarily the sons of host females. Osedax rubiplumus were sampled from submerged whalebones located at 1820-m and 2893-m depths in Monterey Bay, California. Immature females typically did not host males, but mature females maintained male ‘harems’ that grew exponentially in the number of males as female size increased. Allozyme analysis of the females revealed binomial proportions of nuclear genotypes, an indication of random sexual mating. Analysis of mitochondrial DNA sequences from the male harems and their host females allowed us to reject the arrhenotoky and neighbourhood hypotheses for male recruitment. No significant partitioning of mitochondrial diversity existed between the male and female sexes, or between subsamples of worms collected at different depths or during different years (2002–2007). Mitochondrial sequence diversity was very high in these worms, suggesting that as many as 106 females
Comparison of upright inspiratory and expiratory chest radiographs for detecting pneumothoraces

Expiratory films are regarded as being superior to inspiratory films for pneumothorax detection, yet this has not been proved. In the current study, we compared inspiratory versus expiratory chest radiographs for pneumothorax detection.Eighty-five paired inspiratory and expiratory radiographs with pneumothoraces and 93 pairs without pneumothoraces were randomly arranged and reviewed independently by three radiologists. A score of 1-5 was assigned for each hemithorax (5 = definite pneumothorax, 1 = definitely no pneumothorax). Results were compared for inspiration and expiration using receiver operating characteristic (ROC) analysis.The average area under the ROC curves for all readers was .973 for inspiration and .972 for expiration (nonsignificant). McNemar's test and an alpha level of .05 also yielded no significant difference in sensitivity and specificity. Four of the 85 cases were scored as definite pneumothorax on inspiration and as definitely not on expiration by all readers, and three of the 85 ca...
Testability considerations in technology mapping

We consider the problem of incorporating testability into the process of technology mapping. We demonstrate through examples that the testability of technology mapped circuits depends on the technology mapping process, and can be controlled during this process. We then introduce the required concepts to perform technology mapping with testability considerations. We propose a specific technology mapping procedure that accommodates testability as a criterion for selecting the mapping, and present experimental results to demonstrate the tradeoff between area and testability. We also propose a Design-For-Testability procedure that can be incorporated into the technology mapping procedure, and can guarantee complete fault coverage. >
Robust hybrid control for autonomous vehicle motion planning

The operation of an autonomous vehicle in an unknown, dynamic environment is a very complex problem, especially when the vehicle is required to use its full maneuvering capabilities, and to react in real time to changes in the operational environment. A possible approach to reduce the computational complexity of the motion planning problem for a nonlinear, high dimensional system, is based on a quantization of the system dynamics, leading to a control architecture based on a hybrid automaton, the states of which represent feasible trajectory primitives for the vehicle. The paper focuses on the feasibility of this approach, in the presence of disturbances and uncertainties in the plant and/or in the environment: the structure of a robust hybrid automaton is defined and its properties are analyzed. In particular, we address the issues of well-posedness, consistency and reachability. For the case of autonomous vehicles, we provide sufficient conditions to guarantee reachability of the automaton.
Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

Sphingosine 1-phosphate type 1 (S1P(1)) receptor agonists cause sequestration of lymphocytes in secondary lymphoid organs by a mechanism that is not well understood. One hypothesis proposes that agonists act as 'functional antagonists' by binding and internalizing S1P(1) receptors on lymphocytes; a second hypothesis proposes instead that S1P(1) agonists act on endothelial cells to prevent lymphocyte egress from lymph nodes. Here, two-photon imaging of living T cells in explanted lymph nodes after treatment with S1P(1) agonists or antagonists has provided insight into the mechanism by which S1P(1) agonists function. The selective S1P(1) agonist SEW2871 caused reversible slowing and 'log-jamming' of T cells between filled medullary cords and empty sinuses, whereas motility was unaltered in diffuse cortex. Removal or antagonist competition of SEW2871 permitted recovery of T cell motility in the parenchyma of the medulla and resumption of migration across the stromal endothelial barrier, leading to refilling of sinuses. Our results provide visualization of transendothelial migration of T cells into lymphatic sinuses and suggest that S1P(1) agonists act mainly on endothelial cell S1P(1) receptors to inhibit lymphocyte migration.
O (log* n ) algorithms on a Sum-CRCW PRAM

We present work- and cost-optimal O(log*n) algorithms for prefix sums and linear integer sorting on a Sum-CRCW PRAM.
Gold(I) triazolyls: organometallic synthesis in air and aqueous media

(N-heterocyclic carbene)gold(I) alkynyls and organic azides have undergone cycloadditions in water–t-butanol mixtures with copper metal as the pre-catalyst to give new gold(I) triazolyls in high purity. Substrate tolerability was outlined for organoazides bearing a range of functional groups, and branching alpha to the azide moiety. All products are validated by combustion analysis or high-resolution mass spectrometry; two are also confirmed crystallographically.
Progress in the identification of subgroups in ALK-negative anaplastic large-cell lymphoma.

Classification of anaplastic large cell lymphoma: historical background Anaplastic large cell lymphoma (ALCL) represents a group of non-Hodgkin lymphomas of mature T-cell origin (peripheral T-cell lymphomas [PTCLs]) that share common pathologic features, especially the presence of large lymphocytes that often involve lymph node sinuses and express the Ki-1 antigen, now designated CD30 [1]. A chromosomal rearrangement in a subset of these cases, t(2;5)(p23;q35), was found to involve the nucleophosmin gene, NPM1, and a novel tyrosine kinase gene, designated anaplastic lymphoma kinase or ALK [2]. Immunohistochemical staining for ALK allowed recognition that cases with several histologic patterns as well as cases with variant, nonNPM1 partner genes could be unified into a common clinicopathologic entity, ALK-positive ALCL [3]. An additional group of cases lacked ALK rearrangements, and these ALKnegative ALCLs occurred in older patients and had inferior outcomes compared with ALK-positive ALCLs [4]. The fourth edition of the WHO classification of lymphomas provisionally classified ALK-negative ALCL as a distinct entity separate from ALK-positive ALCL [5], and this provisional status is likely to be dropped in a forthcoming WHO update. Nevertheless, diagnostic criteria for ALK-negative ALCL still are evolving, particularly to distinguish it from other CD30positive PTCLs [5–7]. Primary cutaneous ALCL is recognized separately by the WHO and represents ALCLs that present in the skin and typically have excellent long-term outcomes [5]; these tumors share some genetic features with systemic ALCLs, as discussed below. The pathogenic role of ALK fusions in ALK-positive ALCL has been studied extensively; however, the pathobiology of ALKnegative ALCL remains incompletely understood [6]. Gene expression profiling studies have identified a molecular signature for ALK-positive ALCL and another signature common to all ALCLs [7]. This latter signature can help distinguish ALCL from other PTCLs, but identifying a signature specific for ALK-negative ALCL has proved challenging. This difficulty likely relates in part to intrinsic molecular heterogeneity within the category of ALK-negative ALCL.
Character, relative age and implications of fractures and other mesoscopic structures associated with detachment folds: an example from the Lisburne Group of the northeastern Brooks Range, Alaska

ABSTRACT Fractures and other mesoscopic structures formed at different times during the evolution of individual detachment folds in Lisburne Group carbonates of the northeastern Brooks Range. These structures provide clues to the mechanism of folding, the conditions under which folds evolved and the paragenesis of fractures in the fold-and-thrust belt as a whole. The earliest fractures strike NNW and probably represent orogen-normal extension fractures that developed in the foreland basin in advance of the fold-and-thrust belt. These rocks and fractures were later incorporated into the thrust belt, where they were thrust-faulted and folded. Later fractures, strained markers and dissolution cleavage developed during detachment folding as a result of flexural slip and homogeneous flattening. Fracturing associated with flexural slip occurred early in the development of folds. These early fractures were commonly overprinted or destroyed by ductile strain as later homogeneous flattening accommodated additional shortening. This penetrative strain was in turn overprinted by late extension fractures that formed during flexural slip in the waning phases of folding or after folding due to unroofing of the orogenic wedge. Early fracturing, overprinting by ductile structures and subsequent later fracturing in detachment-folded Lisburne Group emphasizes the importance of understanding the unique character and history of each fold-and-thrust belt in a successful hydrocarbon exploration effort. In particular, the mechanical stratigraphy and conditions of deformation play an important role in the type of fold that develops, the fold mechanisms that are active and the subsequent distribution and character of fractures and other mesoscopic structures. 1 Current address: National Park Service, Denali National Park, Alaska USA End_Page 121------------------------
Idiocy and the Law in Colonial New England.

A review of the laws and records of the courts of colonial New England indicate some ways the early settlers thought about and responded to idiocy. Early Massachusetts laws extended certain rights to idiots: They authorized the transfer of property, exonerated idiots who committed capital crimes, and extended relief to idiots who were impoverished. There is no documentation of the implementation of these laws nor is there direct reference to idiocy in court proceedings. Nevertheless, the court records identify certain individuals with incompetence and atypical behavior suggestive of idiocy. Most of the colonial laws as well as the colonists' ways of thinking about idiocy originated in English common law and custom. The New England colonial laws and records of the courts offer insights into contemporary issues regarding mental retardation.
Advances in mapping woody plant canopies using the NASA MISR Instrument on terra

Red (672 nm) band reflectance estimates from the NASA multi-angle imaging spectro-radiometer (MISR) on the earth observing system Terra satellite were used to obtain maps of woody plant fractional crown cover, mean canopy height, and biomass for large parts of south-eastern Arizona and southern New Mexico (>200,000 km2). MISR red band bidirectional reflectance estimates in nine views mapped to a 250 m grid were used to adjust the simple geometric-optical model (SGM) that is based on the principles of Boolean geometry first exploited in Li-Strahler geometric-optical (GO) models. The soil-understory background signal was decoupled a priori by exploiting relationships with the nadir camera reflectance data and the kernel weights of the LiSparse-RossThin kernel-driven bidirectional reflectance distribution function (BRDF) model. Maps of fractional crown cover, mean canopy height, and biomass were produced via retrievals of the mean crown radius and shape parameters from inversion of the SGM using the Praxis algorithm. The mean absolute error in randomly sampled and filtered estimates of fractional crown cover, mean canopy height, and woody biomass was 0.10, 2.2 meters, and 4.5 tons acre-1 (10.1 Mg ha-1), with RMS errors of 0.12, 3.3 and 6.2 (14.0), and coefficients of determination (R2) of 0.78, 0.69, and 0.81, respectively, significant at the 0.01 level (N=576).
Alcohol and adolescents

Alcohol is the most socially acceptable drug in Europe, its use being tolerated and to a greater or lesser extent institutionalized (Royal College of Psychiatrists 1986). Heavy drinking is the norm in some communities. Only recently, many UK business organizations have taken a leaf out of American books and signalled their disapproval of the drinking of alcohol immediately before or during working hours. This is because of its deleterious effects on performance and increased risk of accidents
Optical Diagnostics of a Late Injection Low-Temperature Combustion in a Heavy Duty Diesel Engine

A late injection, high exhaust-gas recirculation (EGR)-rate, low-temperature combustion strategy was investigated in a heavy-duty diesel engine using a suite of optical diagnostics: chemiluminescence for visualization of ignition and combustion, laser Mie scattering for liquid fuel imaging, planar laser-induced fluorescence (PLIF) for both OH and vapor-fuel imaging, and laser-induced incandescence (LII) for soot imaging. Fuel is injected at top dead center when the in-cylinder gases are hot and dense. Consequently, the maximum liquid fuel penetration is 27 mm, which is short enough to avoid wall impingement. The cool flame starts 4.5 crank angle degrees (CAD) after the start of injection (ASI), midway between the injector and bowl-rim, and likely helps fuel to vaporize. Within a few CAD, the cool-flame combustion reaches the bowl-rim. A large premixed combustion occurs near 9 CAD ASI, close to the bowl rim. Soot is visible shortly afterwards along the walls, typically between two adjacent jets at the head vortex location. OH PLIF indicates that premixed combustion first occurs within the jet and then spreads along the bowl rim in a thin layer, surrounding soot pockets at the start of the mixing-controlled combustion phase near 17 CAD ASI. During the mixing-controlled phase, soot is not fully oxidized and is still present near the bowl-rim late in the cycle. At the end of combustion near 27 CAD ASI, averaged PLIF images indicate two separate zones. OH PLIF appears near the bowl rim, while broadband PLIF persists late in the cycle near the injector. The most likely source of broadband PLIF is unburned fuel, which indicates that the near-injector region is a potential source of unburned hydrocarbons.
Identifying common patterns and unusual dependencies in faults, failures and fixes for large-scale safety-critical software

As software evolves, becoming a more integral part of complex systems, modern society becomes more reliant on the proper functioning of such systems. However, the field of software quality assurance lacks detailed empirical studies from which best practices can be determined. The fundamental factors that contribute to software quality are faults, failures and fixes, and although some studies have considered specific aspects of each, comprehensive studies have been quite rare. Thus, the fact that we establish the cause-effect relationship between the fault(s) that caused individual failures, as well as the link to the fixes made to prevent the failures from (re)occurring appears to be a unique characteristic of our work. In particular, we analyze fault types, verification activities, severity levels, investigation effort, artifacts fixed, components fixed, and the effort required to implement fixes for a large industrial case study. The analysis includes descriptive statistics, statistical inference through formal hypothesis testing, and data mining. Some of the most interesting empirical results include (1) Contrary to popular belief, later life-cycle faults dominate as causes of failures. Furthermore, over 50% of high priority failures (e.g., post-release failures and safety-critical failures) were caused by coding faults. (2) 15% of failures led to fixes spread across multiple components and the spread was largely affected by the software architecture. (3) The amount of effort spent fixing faults associated with each failure was not uniformly distributed across failures; fixes with a greater spread across components and artifacts, required more effort. Overall, the work indicates that fault prevention and elimination efforts focused on later life cycle faults is essential as coding faults were the dominating cause of safety-critical failures and post-release failures. Further, statistical correlation and/or traditional data mining techniques show potential for assessment and prediction of the locations of fixes and the associated effort. By providing quantitative results and including statistical hypothesis testing, which is not yet a standard practice in software engineering, our work enriches the empirical knowledge needed to improve the state-of-the-art and practice in software quality assurance.
Infectious Deoxyribonucleic Acid from λ Bacteriophage

T2 and lambda bacteriophage, after treatment with urea, yield infectious material for protoplasts and intact bacterial host cells. After treatment with phenol, lambda bacteriophage yields material, presumably desoxyribonucleic acid, which is infectious for protoplasts but not for intact bacterial host cells. Examination of the composition and structure of lambda desoxyribonucleic acid indicates that it has the conventional double stranded configuration. (auth)
HIFiRE-1 Background and Lessons Learned

*† The Hypersonic International Flight Research Experimentation (HIFiRE) program is a hypersonic flight test program executed by the Air Force Research Laboratories (AFRL) and Australian Defence Science and Technology Organization (DSTO). HIFiRE flight one flew in March 2010. Principle goals of this flight were to measure boundary layer transition (BLT) and shock boundary layer interaction (SBLI) in hypersonic flight. This paper reports background preparation and analysis for HIFiRE-1, and lessons that may be derived from this flight and applied to future hypersonic flight tests, particularly boundary layer transition tests. The boundary layer transition experiment was complicated and compromised to some extent by secondary experiments incorporated into HIFiRE. The high bandwidth instrumentation tested on HIFiRE-1 survived and performed well. The measurement of second-mode instabilities in flight using piezo pressure gauges appears feasible.
Annals of morphology fields and prepatterns. Editorial Festschrift for John C. Carey, MD, MPH.

The investigation of mammalian malformations began to approach human needs in the 19th century with, for example, Meckel's dissection of sibs with the "Meckel" syndrome, his intimation of Hereditat as cause of the condition, his conclusion as to the common causal origin of this specific combination of congenital anomalies, the clear enunciation of the concept of primary malformations, the recognition that many human malformations are normal developmental states in other animals, and that some were normal anatomical states in remote ancestors and now still normal in collateral descendants (atavisms, Darwin's "reversions"; for example, four wings in dipterans, normal in dragonflies and their common ancestor). Later in the century, Wilhelm His Sr. had proposed a schematic map of "organ-forming districts" for prospective chick development, a concept that did not sit well with early workers in developmental biology (e.g., Boveri) until methods became available for a direct experimental "attack" on the embryo. This approach was pioneered by Spemann and Mangold through interspecies transplantation of embryonic rudiments with the spectacular result that set the research stage in developmental biology for the next many years. But it was not until mid-century that the late, great geneticist, Curt Stern, made the His model of chick development more intellectually and experimentally approachable with his meticulous analysis of cuticular appendages of Drosophila, one bristle and one bristle group (field) at a time, in mosaics or gynandromorphs, leading to the ingenious concept of prepatterns. As a basic scientist, Stern did not broaden prepatterns into medicine or to human malformations where it has now found a most gratifying application. This contribution to the Carey Festschrift is to summarize, briefly, field and prepattern theory. © 2016 Wiley Periodicals, Inc.
International Implications of Lead Poisoning in School Aged Children

The United States and the World Health Organization have worked to decrease lead exposure in children, but despite these efforts lead poisoning continues to exist in industrialized and developing countries.┬a Prevention is the only way to preclude the health, academic and behavioral problems that occur due to the effects of lead.┬a Public awareness remains a critical factor in prevention as the problem has not gone away, yet research on the effects of lead poisoning on school aged children is largely absent in educational journals. ┬a┬aThe effect of lead poisoning on health, academics, and behavior is reviewed.┬a
Resource-controlled remote execution to enhance wireless network applications

We present the design and implementation of a system that provides resource-controlled execution environments for client and server application functionality. The system supports a remote execution model that "extends" a client or server endpoint by allowing either to insert functionality at a point along the communication path between the two endpoints. This is especially useful for wireless clients, as resource limited clients can take advantage of nearby processing power, and for clients that access the Internet via a fast wireless LAN, servers can move services close to the base station to reduce latency and improve bandwidth. The system operates entirely at user-level and so is easily deployable, and it supports quality of service in the form of rate-based resource reservations.
Special issue: "MET as actionable target in cancer therapy".

MET (c-Met, or c-MET) receptor is a multifunctional receptor tyrosine kinase that has been known for many years of its pivotal role in human developmental and cancer signaling. The natural ligand for MET is hepatocyte growth factor [HGF; also called scatter factor (SF)], which can act in autocrine, endocrine or paracrine fashion on the MET-expressing epithelial cells (1).
Mapping the complex topological organization of the human parietal face area.

The macaque monkey ventral intraparietal area (VIP) contains neurons with aligned visual-tactile receptive fields anchored to the face and upper body. Our previous fMRI studies using standard head coils found a human parietal face area (VIP+ complex; putative macaque VIP homologue) containing superimposed topological maps of the face and near-face visual space. Here, we construct high signal-to-noise surface coils and used phase-encoded air puffs and looming stimuli to map topological organization of the parietal face area at higher resolution. This area is consistently identified as a region extending between the superior postcentral sulcus and the upper bank of the anterior intraparietal sulcus (IPS), avoiding the fundus of IPS. Using smaller voxel sizes, our surface coils picked up strong fMRI signals in response to tactile and visual stimuli. By analyzing tactile and visual maps in our current and previous studies, we constructed a set of topological models illustrating commonalities and differences in map organization across subjects. The most consistent topological feature of the VIP+ complex is a central-anterior upper face (and upper visual field) representation adjoined by lower face (and lower visual field) representations ventrally (laterally) and/or dorsally (medially), potentially forming two subdivisions VIPv (ventral) and VIPd (dorsal). The lower visual field representations typically extend laterally into the anterior IPS to adjoin human area AIP, and medially to overlap with the parietal body areas at the superior parietal ridge. Significant individual variations are then illustrated to provide an accurate and comprehensive view of the topological organization of the parietal face area.
Regulations on the hygienic design of food processing factories in the United States

Abstract: The regulatory requirements on hygiene control in the design, construction and renovation of food processing facilities in the United States are summarized. Food processing plants in the United States fall under the federal regulatory authority of the Food and Drug Administration (FDA) or the United States Department of Agriculture (USDA). However, state agencies play the major role in approval of hygienic plant design and in the enforcement of the standards. Additional government entities may be involved in a non-regulatory role, such as the USDA Dairy Program. An overview of the applicable federal statutes and regulations is provided, which generally specify performance requirements. The role of third party certifying organizations is explained, as well as the use of guidance and other recommendations. Finally, specific regulations for specialized processes, such as low-acid canning, are discussed.
The production of schistocytes by fibrin strands (a scanning electron microscope study).

The relationship between intravascular coagulation and schistocyte formation has been adequately documented in animal experiments and in in vitro models. A case report is presented of a patient who suffered from micro-angiopathic hemolytic anemia during life as a result of disseminated gastric adenocarcinoma. The fibrin microclots found in his vasculature on postmortem examination indicate that in intravascular coagulation, both in the human and in the experimental animal, fibrin initially polymerizes in the form of fine fibrin strands. These strands, the main etiologic factor in producing schistocytes, are constantly being lysed or rendered amorphous, and rarely persist in postmortem tissues except under unusually favorable conditions. Postmortem histologic study of one case where such favorable conditions did exist indicates the essential identity of the pathologic process in man and in experimental animals.
Status of the BaBar experiment

Abstract This is a status report from the B a B ar experiment at the Stanford Linear Accelerator Center. It has been designed to measure time-dependent asymmetries in the decays of neutral B mesons (CP violation), whose interpretation in the Standard Model is directly related to the parameters of the Cabibbo-Kobayashi-Maskawa mixing matrix.
Biaxial crushing of honeycombs: - Part 1: Experiments

The in-plane compression and crushing of honeycombs is known to be closely related to the crushing behavior of the broader class of space filling cellular solids. Previously, the authors conducted an extensive study of uniaxial crushing of a polycarbonate honeycomb with circular cells. In this paper the same honeycomb is crushed biaxially. The crushing was performed in a custom testing facility between rigid platens which can be moved independently in two orthogonal directions. The facility allows testing at various biaxiality ratios and volume reductions as high as 95%. The facility was used to conduct several series of biaxial crushing experiments on nearly square honeycomb specimens (18×21 cells) . In each experiment we recorded the true stress–displacement responses in the x- and y-directions as well as full field views of the deformation using a video camera. Biaxial crushing is quite complex and the prevalent mechanisms of collapse depend on the biaxiality ratio (γ) . As is the case in uniaxial crushing, the onset of collapse involves localized instabilities, however, the extent of localized deformation varies with γ. The energy absorption capacity of the material depends on γ. The highest energy is required when the specimen is crushed at the same rates in the two directions.
Proceedings of the 16th International Workshop on Mobile Computing Systems and Applications

It is our great pleasure to welcome you to the Sixteenth International Workshop on Mobile Computing Systems -- HotMobile '15. This year's workshop continues the tradition of previous years, being a highly selective venue for mobile computing research. HotMobile '15 again serves its mission as an interactive workshop focused on mobile applications, systems, and environments, as well as their underlying state-of-the-art technologies. The call for papers attracted 85 submissions from Asia, Australia, Europe, North America, and South America. The program committee accepted 23 across a variety of topics, including: understanding human gestures, the Internet-of-things, mobile energy requirements, cellular networks, network monitoring and imaging, location, mobile platforms, learning, and privacy. The program also includes a keynote speech by Mark Corner of Fiksu Inc. and The University of Massachusetts at Amherst examining the tradeoffs between academia and the startup world, the challenges in starting companies, and the calculus for joining them -- along with his startup experience in mobile advertising technology. 16 posters and 7 demos were accepted for display.
Consumer Choice with Consideration Set: Threshold Luce Model

This paper investigates the threshold Luce model, a recently proposed choice model with a threshold for the consideration-set formation. Under the threshold Luce model, consumers first form their consideration set: If an alternative with significantly low utility is dominated by another one, it will not be included in the consideration set. The threshold Luce model can alleviate the independence of irrelevant alternatives (IIA) property and allow more flexible substitution patterns. We characterize the optimal strategy and develop efficient solutions for price and assortment optimization problems. Under the threshold Luce model, the price competition may have zero, one, two, or infinite Nash equilibria, depending on the magnitude of the threshold effect. Moreover, we also develop an efficient estimation method to calibrate the threshold Luce model. Our numerical study on synthetic and real data sets shows that the new model can improve the goodness of fit and prediction accuracy of consumer choice behavior, which suggests the threshold effect should be taken into account in decision making.
Histologic and Endoscopic Similarity between Nodular Gastric Antral Vascular Ectasia and Gastric Hyperplastic Polyps Potentially Causing Treatment Delays

Introduction. Gastric antral vascular ectasia (GAVE) is the underlying cause for 4% of nonvariceal upper GI bleeding. Nodular GAVE and gastric hyperplastic polyps have similar appearance on upper GI endoscopy (EGD) as well as histology, which could delay specific targeted therapy. We herein, through this case, would like to highlight that high clinical suspicion is required to diagnose nodular GAVE. Case Report. A 70-year-old male with a past medical history significant for coronary artery disease s/p drug-eluting stent placement on Plavix, coronary artery bypass grafting, mechanical aortic valve replacement on warfarin, and iron deficiency anemia on replacement was admitted for the evaluation of fatigue and melena for a month. Physical examination was positive for black stool. The only significant lab was a drop in hemoglobin/hematocrit (Hg/dl/H%) of 10/32 to 4/12.5. Fibrosure was sought which suggested that the patient had an F4 cirrhosis. Endoscopy showed nodules in the gastric antrum which were presumptively treated as GAVE with argon plasma coagulation (APC). Surgical pathology showed reactive gastropathy and gastric polyps. Review of the past histology suggested that because of the overlap in the histopathological features of hyperplastic polyps and GAVE, they were misinterpreted as hyperplastic polyp rather than nodular GAVE. Discussion. GAVE can be classified endoscopically as punctate, striped, nodular, or polypoidal form. The light microscopic findings considered specific to GAVE are vascular hyperplasia, mucosal vascular ectasia, intravascular fibrin thrombi, and fibromuscular hyperplasia. However, these findings do not differentiate GAVE from hyperplastic gastric polyp. The first line of treatment for GAVE is endoscopic ablation with Nd:YAG laser or argon plasma coagulation. Response to therapy was seen with a mean of 2.6 treatment sessions. There is not a lot of evidence supportive of pharmacological treatment of GAVE with estrogen-progesterone, tranexamic acid, and thalidomide. Serial endoscopic band ligation as well as detachable snares in the management of nodular GAVE refractory to argon plasma coagulation has also been tried. Conclusion. Oftentimes, there is a delay in the diagnosis and treatment of nodular GAVE as the histopathological appearance could be similar to gastric polyps. The diagnosis of GAVE especially nodular GAVE requires a high level of clinical suspicion. Misdiagnosis of nodular GAVE can delay targeted therapy and have fatal outcomes.
Maternal Dissent in Mainstream News: “Peace Mom” Confronts the Nation’s Strict Father

AbstractScholarly assessment holds that maternal appeals are most progressive when rhetors embed them in a liberal ideological context. This article complicates that claim by considering how mainst...
Effect of Kano model on improving satisfaction of nursing service in outpatient and emergency department of pediatrics

Objective To discuss the effect of Kano model on improving satisfaction of nursing service in outpatient and emergency department of pediatrics.Methods Questionnaires about Kano model on the needs of nursing service in outpatient and emergency department were designed,and the attributes of needs were determined.Children' s needs were included in the nursing service process.And the satisfaction of nursing was investigated and compared before and after by a third party.Results There were ten must-be items (M),nine one-dimensional items (O) and six attractive itmes (A) in Kano model analysis of nursing service.After improving nursing process,the satisfaction rate increased from 78.23％ to 86.30％,with statistically significant difference (x2 =6.536,P ＜ 0.05).Conclusions Kano model can exactly screen the quality attributes of children's and parents' needs of nursing service,and significantly improve satisfaction in outpatient and emergency department of pediatrics. Key words: Data collection; Kano model; Outpatient and emergency department of pediatrics; Nursing service; Satisfaction; Quality attribute
Buckle Up: The Long, Winding Road to Improved Auto Insurance Premiums in Louisiana

Currently, the State of Louisiana has the second most expensive auto insurance in the nation. Louisiana ranks first in an even more devastating automobile insurance statistic, unaffordability. An already poor state simply cannot afford the repercussions of inaction. The higher auto insurance premiums rise, the more Louisiana citizens will forgo insurance coverage, resulting in loss of compensation for victims of automobile accidents and loss of protection for tortfeasors. Many peg the Louisiana tort system as a key factor in the automobile insurance crisis and call for tort reform. This Article closely examines the various legislative efforts of Louisiana tort reform, specifically, proposed amendments to Louisiana Revised Statutes Section 32:295.1 Subsection E, which currently prohibits the admission of evidence that the plaintiff was not wearing a seat belt for purposes of comparative fault and reduction of damages. Several legislators have argued reducing insurance payouts in Louisiana will in turn reduce cost shifting to Louisiana consumers. This Article reviews various Louisiana House and Senate Bills proposed over the last two decades, incorporates interviews with legislators who presented those bills, and distinguishes Louisiana law with the laws of states with the highest and lowest insurance cost, Michigan and Maine respectively. In addition, this Article examines the pros and cons of various proposed alternative tort reform solutions aimed at reducing automobile insurance costs. The author concludes that because the law has sat idle for nearly two decades, it is unknown whether seat-belt evidence admissibility will reduce automobile insurance costs. Tangible data simply does not exist. The author calls for further review of current and proposed Louisiana law and rapid action so that Louisiana citizens do not continue to endure such costly premiums.
A Paradigm Shift for Movement-based Pain Assessment in Older Adults: Practice, Policy and Regulatory Drivers

Abstract Background The profession of nursing has been on the front line of pain assessment and management in older adults for several decades. Self-report has traditionally been the most reliable pain assessment method, and it remains a priority best practice in identifying the presence and intensity of pain. Although advances in technology, biomarkers, and facial cue recognition now complement self-report, it is still important to maximize self-report of pain and to gather understanding of the total pain experience directly from patients. Practices in pain assessment in older adults have evolved over the past 25 years, and current research and quality improvement studies seek not only to detect the presence of pain, but also to determine the best protocol for assessment and most important pain characteristics to assess. Increasing data are now supporting two emerging practices: (1) consistently assessing the impact of pain on function, and (2) measuring pain during movement-based activities rather than at rest. Objective The purpose of this article is thus to discuss the shifting paradigm for movement-based pain assessment in older adults, as well as the practice, policy, and regulatory drivers that support this practice change.
Gender Differences in Classes of Married Men’s and Women’s Depression

Depression is a common presenting problem for couples and family therapy, but it is unclear at what degree close relationships are impaired when testing depression classes. Using a family systems f...
A tale of two counties in the wake of the 2017 hurricane season

Abstract This paper reviews the economies of two small rural communities along the Gulf of Mexico in their recovery from the devastation of Hurricanes Harvey and Irma. Despite extensive economic losses, Aransas County in Texas and Monroe County in Florida appeared to be outliers in the recent history of disaster recovery. Within the first two years of the hurricane events, overall business sales bounced back while the industry mix shifted. Unemployment returned to pre-hurricane levels, but population losses and workforce outflows inhibited employment growth. The conventional community resilience measures understate both areas’ recovery pace due in part to the government relief aid and adaptive capabilities that have accelerated rebuilding efforts.
Ice dynamics will remain a primary driver of Greenland ice sheet mass loss over the next century

The mass loss of the Greenland Ice Sheet is nearly equally partitioned between a decrease in surface mass balance from enhanced surface melt and an increase in ice dynamics from the acceleration and retreat of its marine-terminating glaciers. Much uncertainty remains in the future mass loss of the Greenland Ice Sheet due to the challenges of capturing the ice dynamic response to climate change in numerical models. Here, we estimate the sea level contribution of the Greenland Ice Sheet over the 21st century using an ice-sheet wide, high-resolution, ice-ocean numerical model that includes surface mass balance forcing, thermal forcing from the ocean, and iceberg calving dynamics. The model is calibrated with ice front observations from the past eleven years to capture the recent evolution of marine-terminating glaciers. Under a business as usual scenario, we find that northwest and central west Greenland glaciers will contribute more mass loss than other regions due to ice front retreat and ice flow acceleration. By the end of century, ice discharge from marine-terminating glaciers will contribute 50 ± 20% of the total mass loss, or twice as much as previously estimated although the contribution from the surface mass balance increases towards the end of the century. Changes in ice dynamics in the Greenland Ice Sheet are projected to contribute to significantly more mass loss than previously thought, suggesting that proper calibration and accurate representation of ice-ocean interactions are critical.
Cardio-Cerebral Infarction, Free-Floating Thrombosis and Hyperperfusion in COVID-19

Cardio-cerebral infarction, which refers to an acute ischemic stroke (AIS) and acute myocardial infarction (AMI) that occur concurrently, is an uncommon phenomenon with a grave prognosis. Intraluminal carotid thrombus (ICT) is an infrequently encountered cause of ischemic stroke and can be associated with an underlying hypercoagulable state. One severe yet prevalent complication of infection with Coronavirus Disease 2019 (COVID-19) is thrombosis from multi-pathway inflammatory responses. Here, we present a unique case of cardio-cerebral infarction, with a free-floating intraluminal thrombus in the left internal carotid artery, in the setting of recent COVID-19 infection, and with the etiology of both events attributed to a COVID-19 hypercoagulable state. CT perfusion imaging also showed an interesting imaging finding of hyperperfusion, which is believed to be a form of dysfunctional cerebral autoregulation.
Ultrasensitive ultrasound imaging of gene expression with signal unmixing

Acoustic reporter genes (ARGs) that encode air-filled gas vesicles enable ultrasound-based imaging of gene expression in genetically modified bacteria and mammalian cells, facilitating the study of cellular function in deep tissues. Despite the promise of this technology for biological research and potential clinical applications, the sensitivity with which ARG-expressing cells can be visualized is currently limited. Here we present burst ultrasound reconstructed with signal templates (BURST)—an ARG imaging paradigm that improves the cellular detection limit by more than 1,000-fold compared to conventional methods. BURST takes advantage of the unique temporal signal pattern produced by gas vesicles as they collapse under acoustic pressure above a threshold defined by the ARG. By extracting the unique pattern of this signal from total scattering, BURST boosts the sensitivity of ultrasound to image ARG-expressing cells, as demonstrated in vitro and in vivo in the mouse gastrointestinal tract and liver. Furthermore, in dilute cell suspensions, BURST imaging enables the detection of gene expression in individual bacteria and mammalian cells. The resulting abilities of BURST expand the potential use of ultrasound for non-invasive imaging of cellular functions. Acoustic reporter genes can be imaged with high sensitivity using the BURST imaging sequence, allowing the detection of single cells under optimal conditions.
"I talked to a couple of friends that had it": Informal feminized health networks and contraceptive method choices.

Abstract Scholars recognize that social networks can influence a number of health behaviors, including women's contraceptive method choices. However, the gendered dynamics underlying the process of using non-medical information sources to make decisions about contraception has received less attention. Using 30 semi-structured interviews with women enrolled in a contraceptive initiative in the western United States, we explore how women use gendered understandings of medicine and feminized social networks to make decisions about contraceptives. Frequently categorizing their experiences in medical settings as unsatisfactory, women often turn to social support networks of other women—what we call “informal feminized health networks”—to gather information about the effects of contraceptives on women's bodies and to make decisions about which contraceptives are best. While informal feminized health networks are useful, women utilize them in light of unsatisfactory experiences in clinical settings. Working to uproot the paternalistic legacy of institutionalized medicine and improving provider-patient communication will enhance contraceptive access and help women reach their reproductive goals.
Identification of a novel member of the T1R family of putative taste receptors

In the gustatory system, the recognition of sugars, amino acids and bitter-tasting compounds is the function of specialized G protein-coupled receptors. Recently, two members of novel subfamily of G protein-coupled receptors were proposed to function as taste receptors based on their specific expression in taste receptor cells. Here, we report the identification of a third member, T1R3, of this family of receptors. T1R3 maps near the telomere of mouse chromosome 4 rendering it a candidate for the Sac locus, a primary determinant of sweet preference in mice. Consistent with its candidacy for the Sac locus, T1R3 displays taste receptor cell-specific expression. In addition, taster and non-taster strains of mouse harbor different alleles of T1R3.
Amino acid composition and properties of crystalline lactate dehydrogenase X from mouse testes.

Lactate dehydrogenase (LDH) X has been isolated in crystalline form from mouse testes. Homogeneity of the protein preparation was established by disc gel electrophoresis, analytical ultracentrifugation, and immunochemical analyses. LDH-X is clearly distinct in amino acid composition from LDH-1 and LDH-5 with respect to numbers of residues of leucine, glycine, threonine, and methionine. When 6 to 8 moles of p-hydroxymercuribenzoate are bound per mole of LDH-X substantial enzymic activity remains. A molecular weight of 140,000, comparable to that of beef heart LDH-1, was determined for LDH-X by zone velocity sedimentation in an isokinetic sucrose gradient. When LDH-X is incubated at 65° for 20 min it retains 65% of its original activity as compared to the virtually complete inactivation of LDH-1 and LDH-5.