cssi/SciSciGPT-SciSciNet huggingface dataset:
HybriDiagnostics: Evaluating Security Issues in Hybrid SmartHome Companion Apps

This work presents HybriDiagnostics, a vulnerability-assessment framework that identifies nine preexisting security issues in IoT companion apps built using hybrid app development frameworks. At the heart of HybriDiagnostics is an analysis engine that identifies misconfigured policies (including Content Security Policy, and whitelist), usage of inline scripts, unsafe eval() usage, unsafe HTML and JQuery APIs and attributes, unencrypted storage, usage of vulnerable Cordova SDKs and more. The results of the analyses are documented in a security assessment report.A set of 102 Apache Cordova, Ionic, Monaca, OnsenUI, Phonegap, and Framework7 smarthome apps are analyzed to identify the security issues. For each security issue, either a proofof-concept attack or a hypothetical attack scenario is presented to demonstrate how the issue can be exploited to launch a serious cyberattack against the companion IoT device or the smartphone itself and compromise user privacy.
Conditional depletion of the acetyltransferase Tip60 protects against the damaging effects of myocardial infarction.

Abstract Injury from myocardial infarction (MI) and consequent post-MI remodeling is accompanied by massive loss of cardiomyocytes (CM), a cell type critical for contractile function that is for all practical purposes non-regenerable due to its profound state of proliferative senescence. Identification of factors that limit CM survival and/or constrain CM renewal provides potential therapeutic targets. Tip60, a pan-acetyltransferase encoded by the Kat5 gene, has been reported to activate apoptosis as well as multiple anti-proliferative pathways in non-cardiac cells; however, its role in CMs, wherein it is abundantly expressed, remains unknown. Here, using mice containing floxed Kat5 alleles and a tamoxifen-activated Myh6-MerCreMer recombinase transgene, we report that conditional depletion of Tip60 in CMs three days after MI induced by permanent coronary artery ligation greatly improves functional recovery for up to 28 days. This is accompanied by diminished scarring, activation of cell-cycle transit markers in CMs within the infarct border and remote zones, reduced expression of cell-cycle inhibitors pAtm and p27, and reduced apoptosis in the remote regions. These findings implicate Tip60 as a novel, multifactorial target for limiting the damaging effects of ischemic heart disease.
How to study movement in children

Publisher Summary The chapter is divided into six sections: First, a brief review of the past 25 years of motor development research, focusing primarily on the style of inquiry and the nature of the dependent variables used. Second, a discussion of the dependent variables that traditionally measures the product rather than the process of movement, and the ways in which their contribution to the description and analysis of movement patterns in children has both helped and constrained progress. Third, the movement studies of children incorporating the ecological perspective. Fourth, research on fetal motor activity is reviewed in the chapter. Fifth, a discussion of periodicity in motor behavior; the ways in which it is measured and its promise in understanding movement behavior is illustrated in the chapter. A sixth and final section summarizes the chapter and comments on future directions and initiatives, one of which is the use of allometry as a technique for studying movement patterns in children.
Utilization of heavy alkali dopants as a beacon to study the cathode electrolyte decomposition layer in lithium-ion batteries

We introduce low levels of CsClO4 and RbClO4 into the electrolyte of LiCoO2 electrochemical half-cells to probe the composition of the passivation film on the surface of the cathode, the electrolyte decomposition layer (EDL). The advantages of these heavy alkali dopants lie in their large ionic radii, which limit intercalation, yet their strong light scattering cross-section creates a beacon that highlights the formation of products near the cathode surface. Detailed surface analysis and depth profiling with X-ray photoelectron spectroscopy, and bulk analysis utilizing X-ray absorption spectroscopy, show evidence for the formation of Cs/Rb compounds, such as carbonates, halides, and perchlorates, similar to those formed by lithium in previous studies, but also reveal the significantly reduced mobility of the Cs/Rb relative to Li in the non-uniform EDL. This unique approach could open several presently untapped techniques to gather new information on the EDL in Li-ion batteries.
Calculation of average and variance bus currents for reliability analysis of VLSI CMOS circuits

Techniques for calculating average and variance of currents in various branches of power and ground buses are presented. These current estimates can be used to estimate mean time to failure due to electromigration in sections of the buses and to redesign them, if necessary, so that the electromigration failures over the estimated lifespan of the chip are minimized. The validity of the approach rests on the assumption that the bus can be modeled as a linear resistive network. The sparsity of this network is exploited to speed up the calculation of averages and variances. It is necessary to formulate and LU factorize the node admittance matrix only once. >
Human Signal Recognition Particle (SRP) Alu-associated Protein Also Binds Alu Interspersed Repeat Sequence RNAs CHARACTERIZATION OF HUMAN SRP9

Nearly 1 million interspersed Alu elements reside in the human genome. Alu retrotransposition is presumably mediated by full-length Alu transcripts synthesized by RNA polymerase III, while some polymerase III-synthesized Alu transcripts undergo 3'-processing and accumulate as small cytoplasmic (sc) RNAs of unknown function. Interspersed Alu sequences also reside in the untranslated regions of some mRNAs. The Alu sequence is related to a portion of the 7SL RNA component of signal recognition particle (SRP). This region of 7SL RNA together with 9- and 14-kDa polypeptides (SRP9/14) regulates translational elongation of ribosomes engaged by SRP. Here we characterize human (h) SRP9 and show that it, together with hSRP14 (SRP9/14), forms the activity previously identified as Alu RNA-binding protein (RBP). The primate-specific C-terminal tail of hSRP14 does not appreciably affect binding to scAlu RNA. Kd values for three Alu-homologous scRNAs were determined using Alu RBP (SRP9/14) purified from HeLa cells. The Alu region of 7SL, scAlu, and scB1 RNAs exhibited Kd values of 203 pM, 318 pM, and 1.8 nM, respectively. Finally, Alu RBP can bind with high affinity to synthetic mRNAs that contain interspersed Alus in their untranslated regions.
Sex Determination from the Second Cervical Vertebra: A Test of Wescott’s Method on a Modern American Sample*

: Numerous methods for establishing a biological profile exist; however, many of these methods rely on the recovery of several specific bones or on fragile skeletal elements that are sometimes irrecoverable. It is for this reason new methods utilizing other previously under-documented bones should be established and tested by the forensic anthropological community. This study tests the accuracy of Wescott’s (J Forensic Sci 2000;45(2)) method for determining sex from the second cervical vertebra. Specimens were drawn from the donated skeletal collection curated at the Hamilton County Forensic Center (n = 57) and the William M. Bass Donated Skeletal Collection (n = 243). Both intra- and inter-observer error rates were low and accurate classifications ranged from 78% (females-Function 1) to 90.6% (males-Function 5). Of the five functions, Function 4 achieved the highest overall accuracy, with 260 individuals (86.7%) falling into the correct category. Overall, this method is an effective classificatory tool for sex estimation.
Evidence Based Medicine Teaching in Undergraduate Medical Education: A Literature Review

Objectives – To determine the year when evidence based medicine (EBM) was introduced and the extent to which medical students were exposed to EBM in undergraduate medical education and to investigate how EBM interventions were designed, developed, implemented, and evaluated in the medical curriculum. Methods – A qualitative review of the literature on EBM interventions was conducted to synthesize results of studies published from January 1997 to December 2011. A comprehensive search was performed on PubMed, CINAHL, Web of Science, Cochrane Library, ProQuest Dissertations & Theses, PsycINFO, and ERIC. Articles were selected if the studies involved some form of quantitative and qualitative research design. Articles were excluded if they studied EBM interventions in medical schools outside the United States or if they examined EBM interventions for allied health profession education or at the levels of graduate medical education and continuing medical education. Thirteen studies which met the selection criteria were identified and reviewed. Information was abstracted including study design, year and setting of EBM intervention, instructional method, instruction delivery format, outcome measured, and evaluation method. Results – EBM was introduced to preclinical years in three studies, integrated into clinical clerkship rotations in primary care settings in eight studies, and spanned preclinical and clinical curricula in two studies. The duration of EBM interventions differed, ranging from a workshop of three student contact hours to a curriculum of 30 student contact hours. Five studies incorporated interactive and clinically integrated teaching and learning activities to support student learning. Diverse research designs, EBM interventions, and evaluation methods resulted in heterogeneity in results across the 13 studies. Conclusions – The review reveals wide variations in duration of EBM interventions, instructional methods, delivery formats for EBM instruction, implementation of an EBM intervention, outcomes measured, and evaluation methods, all of which remain relevant issues for further research. It is important for medical educators and health sciences librarians to attend to these issues in designing and delivering a successful EBM intervention in the undergraduate medical curriculum.
Immunology of the aging lung

The aging process is associated with multiple deficits in pulmonary immune function. Defense of the airway is impaired in the elderly by decreased mucociliary clearance, alteration in respiratory mechanics and, in some cases, concomitant illnesses that predispose to aspiration. Alveolar defenses can be divided into resident defense mechanisms, inflammatory responses, and specific immune responses. Resident defenses such as macrophage phagocytosis and chemotaxis, although largely intact, may have subtle defects under specific conditions. Inflammatory responses may also be diminished, as evidenced by decreased neutrophil-mediated killing and chemotaxis. Specific immune responses appear to be the most vulnerable to age-associated impairment. Although antigen presentation is well preserved during aging, accessory cell cytokine production may be decreased. T-lymphocyte proliferative responses are markedly decreased, as is the production of and response to intercellular mediators. Age-associated alterations in T cell subpopulations may result in imperfect T cell-B cell interactions leading to expression of abnormal immunoglobulins. These many interacting and compounding impairments may explain the increased susceptibility of the elderly to pulmonary infection and autoimmune diseases.
The Genetic Code-Like Transformations and Their Effect on Learning Functions

The natural gene expression process evaluates the fitness of a DNA-string through a sequence of representation transformations. The genetic code defines one such transformation in this process. This paper shows that genetic code-like transformations introduce an interesting property in the representation of a genetic fitness function. It points out that such adaptive transformations can convert some functions with an exponentially large description in Fourier basis to one that is highly suitable for polynomial-size approximation. Such transformations can construct a Fourier representation with only a polynomial number of terms that are exponentially more significant than the rest when fitter chromosomes are given more copies through a redundant, equivalent representation. This is a very desirable property [2, 3] for efficient function-induction from data which is a fundamental problem in learning, data mining, and optimization.
A transaction-oriented approach to attribute partitioning

Abstract This study introduces the concepts of sufficient and support to design two methods for solving the attribute partitioning problem: MAX and FORWARD SELECTION. These concepts express the simple idea that in order to minimize costs, a segment should contain all the attributes required by some transaction(s) and exclude other attributes. Contrary to all previous studies which without exception treat the attribute as the decision variable and may become computationally infeasible when the number of attributes is large (a condition favoring attribute partitioning), these two methods treat the transaction as the decision variable and their run time is not affected by the number of attributes. Both methods generate excellent results without using complicated mathematics. They also take into account the complexity caused by the interaction between attribute partitioning and access path selection, an issue most previous studies fail to address. Besides, both methods provide detailed information normally not available from other methods. This information provides new insight into the process of attribute partitioning. MAX is for cases involving a modest number of transactions (⩽15), FORWARD SELECTION for cases involving a large number of transactions.
Implication of hysteretic selector device on the biasing scheme of a cross-point memory array

We analyze the effect of hysteresis in the correlated material (CM) based selector devices on the choice of the word-line and bit-line voltages of a cross-point memory array. Considering a magnetic tunnel junction as the memory device, we also evaluate the dependence of array leakage and performance on the CM characteristics. While insulator-to-metal transition (IMT) in the CM plays a pivotal role in determining the voltage biases for proper functionality, we show that metal-to-insulator transition (MIT) also has an important effect on the array power-performance. If MIT switching time is large compared to the setup time, the read/write speed may be limited by MIT, resulting in performance loss. We show that the performance can be recovered by choosing appropriate voltage biases. We define the region of operation for the voltage biases constrained by MIT to ensure no performance penalty due to metal-to-insulator transition. For the read operation, MIT constrained region of operation leads to minimal or no leakage penalty. Thus, optimal choice of bias voltages for read yields maximum performance and energy efficiency. However, for the write operation, high write voltage shrinks the region of operation, thus offering limited choices for the voltages, leading to leakage increase. The leakage penalty reduces with decreasing hysteresis of the CM. While leakage increase at iso-performance can be as large as 21X for 75mV of hysteresis, it reduces to 2.6X for hysteresis of 28mV. For hysteresis > 100 mV, the MIT constrained region of operation vanishes and the only design choice that remains is increasing the write cycle time.
Chapter 12 Plasticity and commitment in the developing cerebral cortex

Publisher Summary This chapter discusses the processes that generate commitment to individual neuronal phenotypes in the developing cerebral cortex. Studies of early cortical development reveal that environmental influences apparently play critical roles in determining the fates of neurons. Transplantation experiments indicate that early cortical progenitor cells are multipotent and capable of producing neurons destined for several cortical layers. During their final cell cycle, however, neurons make a commitment to a particular laminar fate; this commitment endows the newly postmitotic cell with the information it needs to home to a specific cortical layer and to send an axon to an appropriate target. In the tangential domain, lineage experiments and observations of migrating cortical cells suggest that neurons can disperse tangentially away from their point of origin in the ventricular zone, even into distinct cortical areas. Transplantation experiments have shown that both the area-specific axonal connections and cytoarchitectonic features of neocortical neurons are malleable, again suggesting that interactions with other cells or the local environment play an instructive role in the determination of cortical cell fates.
Androgen deficiency syndrome in older people.

Purpose To support nurse practitioners in their encounters with aging male patients with signs and symptoms related to the decline of male sex hormones. Data sources An electronic search was conducted on studies from 2006 to 2013 from the following databases: PubMed, CINAHL, Scopus, and related health resources websites. The search terms used included male menopause, andropause, androgen deficiency, testosterone deficiency, late-onset hypo-gonadism, and testosterone replacement therapy. Relevant studies in English were selected for an integrative review. Conclusions Androgen deficiency syndrome has been overlooked in clinical settings. However, there has been an increase in health needs related to low testosterone levels. A diagnosis should be made carefully, considering other possible causes of the problems as well as the decision to initiate testosterone treatment (TT) and monitoring. In this article, the current awareness of androgen deficiency syndrome, pathophysiology of aging men's sex organ, clinical presentation, differential diagnoses, diagnostic strategy, clinical management, monitoring, and referral plans are discussed. Implications for practice The rapidly growing aged population in our society makes androgen deficiency syndrome a growing issue that needs to be understood, adequately diagnosed, and carefully managed by nurse practitioners.
The radialist's religious fervor: Praise the Lord, I Am a Believer in Treating CTOs and the Radial Approach.

Key Points The MATRIX Trial proved that radial was superior to femoral in ACS patients due to reduction in complications with equal effectiveness. This large study suggests that the radial approach can be equally successful compared to the femoral approach in CTOs. Since so few radial CTO procedures were included, one wonders whether CTO operators with MATRIX-like radial experience could have less complications than the femoral approach in these procedures.
Conditions for a successful status elevation ceremony

Status elevation ceremonies are the mirrored parallel processes of Garfinkel's (1956) status degradation ceremonies, applied to the acquisition of a higher status or preferred identity, resulting from elaborate mythological rituals. Spoiled, stigmatized identities are prime populations for the deconstruction and reconstruction of new identities. Garfinkel's steps are extended, analyzed, and reapplied to a community of actors with degraded identities who seek a persona of a more socially acceptable, elevated status. The interactionist processes of rites of passage are applied to these reconstituted identities. Situated actions and vocabularies of motives are central features to adopting new lines of conduct.
First-order interaction energies and the basis set truncation effects

The basis set superposition error is investigated in terms of the first-order symmetry adapted perturbation theory (SAPT). The analysis of the first-order SAPT contribution to the interaction energy reveals the origin of the basis set truncation effects at both the one-electron and many-electron levels of approximation. This helps to formulate the necessary conditions which ensure that the calculated interaction energy is free of the basis set superposition contributions. At the level of the one-electron approximation used for both the interacting system and its subsystems a part of the basis set truncation errors can be eliminated by using what is called the dimer-centred basis set. In order to remove all contributions which arise from the symmetrization of the product of wave functions of the subsystems one needs to redefine their reference states. This means that for the interacting system represented by a single HF determinant, the subsystems must be considered at the level of full CI in the orbital s...
Multiple jejunoileal and colonic atresias: Case report and review of literature

Multiple intestinal atresia (MIA) associated with colonic atresia is very rare, especially with almost normal bowel length. This report deals with a case of multiple jejunoileal atresia associated with descending colon atresia, which was managed by multiple resection and primary anastomoses without use of stents and with total parenteral nutrition. Literature on the genesis, management and survival of MIA is reviewed.
Gonadotropin-Releasing Hormone Modulation of Protein Kinase-C Activity in Per if used Anterior Pituitary Cell Cultures

The ability of GnRH to modulate protein kinase- C (PKC) activity was examined in perifused rat pituitary cell cultures. Under these conditions, LH release and GnRH receptor number remained unchanged after repeated pulses of 1 nM GnRM, whereas PKC (measured both enzymatically and by radioligand assay) showed an initial increase in kinase activity after the first pulse of GnRH (-2-fold), followed by downregulation of PKC activity with subsequent pulses of the releasing hormone. It was also observed that the GnRH-stimulated down-regulation of PKC was dependent on the presence of extracellular calcium, which was not the case for the initial upregulation of PKC. These findings are consistent with a modulating role of the GnRH receptor on PKC activity through a Ca2+-dependent process. This study also provides further evidence that GnRH-stimulated LH release and PKC activity can be uncoupled. (Endocrinology 127: 2393–2399, 1990)
Teachers for changing schools

We expect the teachers and administrators in our schools to be knowledgeable, skillful, concerned, and effective professionals. We have established certification standards to ensure, insofar as possible, that they are. We provide a great number and variety of programs to prepare them for careers in schools and assist them in maintaining, refining and extending their competence as practicing professionals.
A Distinct Mechanism for Coactivator versus Corepressor Function by Histone Methyltransferase G9a in Transcriptional Regulation

Histone methyltransferase G9a has been understood primarily as a corepressor of gene expression, but we showed previously that G9a positively regulates nuclear receptor-mediated transcription in reporter gene assays. Here, we show that endogenous G9a contributes to the estradiol (E2)-dependent induction of some endogenous target genes of estrogen receptor (ER)α in MCF-7 breast cancer cells while simultaneously limiting the E2-induced expression of other ERα target genes. Thus, G9a has a dual and selective role as a coregulator for ERα target genes. The ERα binding regions associated with the pS2 gene, which requires G9a for E2-induced expression, are transiently occupied by G9a at 15 min after beginning E2 treatment, suggesting that G9a coactivator function is by direct interaction with ERα target genes. Transient reporter gene assays with deletion mutants of G9a demonstrated that domains previously associated with the corepressor functions of G9a (C-terminal methyltransferase domain, ankyrin repeat domain, and cysteine-rich domain) were unnecessary for G9a coactivator function in ERα-mediated transcription. In contrast, the N-terminal domain of G9a was necessary and sufficient for enhancement of ERα-mediated transcription and for E2-induced occupancy of G9a on ERα binding sites associated with endogenous target genes of ERα. In addition to a previously identified activation domain, this region contains a previously uncharacterized ligand-dependent ERα binding function, indicating how G9a is recruited to the target genes. Therefore, the coactivator and corepressor functions of G9a involve different G9a domains and different molecular mechanisms.
Synthesis and ex vivo autoradiographic evaluation of ethyl-β-d- galactopyranosyl-(1,4′)-2′-deoxy-2′-[18F]fluoro- β-d-glucopyranoside-a novel radioligand for lactose-binding protein: Implications for early detection of pancreatic carcinomas with PET

Introduction Previous studies demonstrated that the lactose-binding protein (hepatocellular carcinoma–intestine–pancreas and pancreatitis-associated proteins (HIP/PAP)) is upregulated >130 times in peritumoral pancreatic tissue as compared to normal pancreatic tissue. Therefore, we developed a new radiolabeled ligand of HIP/PAP, the ethyl-β-d-galactopyranosyl-(1,4′)-2′-deoxy-2′-[18F]fluoro-β-d-glucopyranoside (Et-[18F]FDL) for noninvasive imaging of pancreatic carcinoma using positron emission tomography and computerized tomography (PET/CT).
The double centralizer theorem for division algebras

AssumeV is a finite-dimensional vector space over a division ringD having centerF. It is shown that ifT∈ End D (V) is algebraic overF then the double centralizerC(C(T)) ofT is the setF[T] of all polynomials inT with coefficients fromF. Consequently, eachn×n matrix ring overD is an algebraicF-algebra if and only ifC(C(T))=F[T] for allT and all finite-dimensionalV.
A SIMPLIFIED RECORDING POTENTIOMETER.

Some years ago (1) the author described a recording potentiometer designed primarily to meet the requirements of flexibility so necessary in physiological work. A number of these instruments were built and are still in use. Ever since this earlier instrument was developed the writer has continued to improve and simplify until now one which is far superior in all respects to this first instrument has been constructed. This instrument is fundamentally a self-balancing potentiometer controlled by radio tubes. It differs from the earlier model, however, in being much more sensitive, stable, compact, and particularly mechanically reliable. All parts used in its construction are standard and only a minimum amount of machining is
Functional CCR5 Receptor Protects Patients With Arthritis From High Synovial Burden of Infecting Chlamydia trachomatis

Abstract Introduction The CCR5 chemokine receptor occurs in a wild-type (wt) and a nonfunctional deleted form (Δ32). Reports suggested that Chlamydia -induced reproductive tract pathology is attenuated in women bearing Δ32. The authors asked whether the mutation affects synovial prevalence and burden of Chlamydia trachomatis . Methods Polymerase chain reaction (PCR) defined CCR5 genotype in synovial tissue DNA from 218 individuals: 21 controls, 110 with reactive arthritis (ReA), 83 with undifferentiated oligoarthritis (UO), 4 with osteoarthritis (OA). Disease durations were 0.5 to 21 years. Additional PCR assays defined the presence of C trachomatis DNA. Bacterial load was assessed by real-time PCR in selected samples. Results Five controls were wt/Δ32, 16 were wt/wt; 2 of 21 controls (both wt/wt) were PCR positive for C trachomatis . Eighty-five (44%) patients with arthritis were PCR positive for C trachomatis (69 ReA and 16 UO). For patients with ReA, 14 (13%) had wt/Δ32, 10 (71%) of whom were PCR positive. Nineteen patients with UO (23%) were wt/Δ32, with 1 (1%) PCR positive. No differences existed for gender or other factors. One patient with OA had wt/Δ32. In ReA and UO samples, wt/Δ32 heterozygotes had a 5- to 10-fold higher bacterial burden than did wt/wt patients ( P = 0.03), regardless of diagnosis. Conclusion These results indicate that the wt/wt genotype is associated with attenuated synovial bacterial load compared with loads in wt/Δ32 patients. Although no alleles other than Δ32 were assessed, our data suggest that this allele provides little/no protection from ReA in patients infected with Chlamydia - but it may provide some protection in patients with UO. The basis of this possible differential effect of CCR5 genotype is under study.
Nurse manager engagement: what it means to nurse managers and staff nurses.

Objective To describe what nurse manager engagement means to nurse managers and staff nurses by incorporating an organizational dashboard to document engagement outcomes. Background Retaining engaged nurse managers is crucial for individual performance and organizational outcomes. However, nurse manager engagement is currently underreported in the literature. Methods Existing data from the 2010 Employee Opinion Survey at the Baylor University Medical Center in Dallas, Texas, were used to measure staff engagement among 28 nurse managers and 1497 staff nurses. Results The data showed a 21% gap between manager and staff nurse engagement levels, with managers showing higher engagement levels than staff. No clear depiction of nurse manager engagement emerged. Consequently, an expanded definition of nurse manager engagement was developed alongside a beginning dashboard of engagement outcomes. Conclusions The findings have implications for overcoming barriers that affect staff nurse engagement, improving outcomes, and creating definitions of nurse manager engagement.
UV Radiation Effects on the Sol-Gel Processing of Ferroelectric PZT Thin Films

Sol gel solutions have been modified with hydrogen peroxide to improve the durability of photo-irradiated films to water and acidic solvents for photo-patterning. The solutions used for film fabricati.on are aqueous based and contain acetylacetonate (acac). UV-Vis absorption studies indicate that peroxide modifies the acetylacetonate ligand (in this case the zirconium precursor) creating a new absorbing species at longer wavelength which also affects the response of the acac ligand to UV radiation. Precursor modification and UV treatments have also been shown to impact the texture and improve the microstructure of resulting films. Depth profiling by radio-frequency glow discharge atomic emission spectroscopy indicates reduction in the carbon to hydrogen ratios of films crystallized after exposure to UV radiation.
On the karyotype of the tahr Hemitragus jemlahicus and the Y-chromosome of goats and sheep.

Somatic chromosomes of a female and male Himalayan thar, Hemitragus jemlahicus (H. Smith) are described. The diploid number is 48, there are 12 atelocentric and 34 telocentric autosomes in both sexes, the X-chromosome is meta- or submetacentric. The morphological appearance of the Y-chromosome is compared with that of other bovid species including recent observations on the goat Capra hircus.
Effects of hydrodynamic and colloidal forces on the coagulation of dispersions

Abstract Carefully controlled experiments have been conducted to study the effects of hydrodynamic forces on stability of colloids. Results are compared, where possible, to the theory presented earlier, as well as to other experiments. Experiments were performed in a cylindrical Couette device with a dilute suspension of monodisperse (diameter = 500 nm) polystyrene spheres. Both Brownian and shear-induced coagulation experiments were performed. Suspensions with volume fractions of the order of 10−5 were sheared at shear rates ranging from 102 to 2 × 103 sec−1. A low-angle laser light scattering technique was used to determine the degree of coagulation for various times of shearing. From combinations of theory and experiment one can estimate the value of the Hamaker constant. For both rapid Brownian and rapid shear-induced coagulation experiments, the Hamaker constant A ≌ 2 × 10 −21 J. When electrostatic repulsion is appreciable, the rate of shear-induced coagulation is greatly decreased. Under these conditions it appears that effects of Brownian and hydrodynamic forces must be considered simultaneously. It was also found that, under conditions of slow coagulation, the stability ratio is dependent on aggregate size, a result predicted by the theory.
Three lacunae of cognitive therapy

This article discusses three lacunae of cognitive therapy: investigations of cognitive histories, levels of cognitions' accessibility, and interactions among cognitions. The role of cognitions in psychotherapy is described and ways in which psychoanalysis and cognitive therapy complement each other are discussed. The growing concern of cognitive psychology with levels of processing and preattentive mechanisms is shown to resemble certain directions within psychodynamic theory. By viewing personality as an open system, influenced by experiential inputs throughout life, certain theoretical convergences become evident and lay the groundwork for future research directions.
Globin proteins of the normal and anemic duck

The red blood cells of normal adult ducks contain two main hemoglobins. The most abundant type, HbA, comprises approximately 80% of the total, with the remaining 20% being made up of HbD. An attempt was made to determine whether during hemolytic anemia a special alpha globin chain (alpha s) replaces the alpha chain of HbA found in normal animals. This special stress alpha globin, whose existence has been seriously questioned, was originally postulated to explain the sequence discrepancies obtained between alpha chains of normal and anemic chickens and ducks. Using gel electrophoresis, isoelectric focusing, and HPLC peptide mapping techniques no qualitative differences between the alpha A globins of normal and anemic animals were found. The nature of the beta globin chains present in adult ducks has also never been rigorously established. In this work, a variety of techniques, including HPLC, gel electrophoresis, and microcolumn amino acid analysis, were used to examine the beta chains from each hemoglobin. Using these methods, no differences were found between the beta globin chains of the two hemoglobins.
A university-wide model for coordinating internships

Colleges and universities of varying enrollments and academic missions can implement a university-wide model for coordinating internships and other credit-generating field experiences by following and/or modifying a program developed at Illinois State University. All credit-generating supervised work experiences in local, state, national and international businesses, agencies, institutions and organizations areplanned, administered andsupervised at the department level and coordinated through a university-wide central office which functions as a clearing house and resource center for students, faculty, administrators and potential employers. The program does not include those experiences associated with Teacher Education.
Clustering of rare earths in GeAs sulfide glass

Abstract Clustering of rare-earth dopants in GeAs sulfide glasses was studied by fluorescence spectroscopy of Pr-doped glasses and by EPR measurements of Gd-doped samples. The linewidth of the g ∼ 2 resonance of Gd3+, as well as the relative intensity of emission from the 1D2 level of Pr3+, was used as a relative measure of rare-earth clustering. Rare earths were found to have low solubility in uncodoped GeAs sulfide glasses, which also displayed poor fluorescence efficiency due to severe clustering. Codoping such glasses with Ga greatly enhanced rare-earth solubility and dispersal, particularly for Ga:rare earth ratios ≥ 10:1, as evidenced by the narrower EPR resonances and more intense luminescence of Gd- and Pr-doped glasses, respectively. In, P and Sn were also observed to ‘decluster’ rare earths, although less efficiently than Ga, whereas codoping with I was found to have no effect on clustering. These phenomena are explained by a structural model in which (1) rare-earth dopants and codopants are spatially associated and (2) rare-earth dispersal is accomplished by a statistical distribution of codopants in tetrahedral network sites.
Shielding by an electron surface layer

We seek to determine whether the shielding observed in the electron free-fall experiment could be performed by electrons in a surface layer. An idealized model is used to estimate the shielding of the uniform electric field produced by the gravitational compression of the ionic lattice. We allow for the possibility that the charges in the surface layer can obey either Fermi or Bose statistics. Neither a two-dimensional Fermi gas nor a two-dimensional lattice of electrons provides sufficient shielding at low temperature. A condensed Bose film could account for the magnitude of the shielding at low temperatures, although the predicted condensation temperature is considerably lower than the transition temperature observed in the experiment. Either a nondegenerate Bose film or a two-dimensional Fermi gas could account for the field observed above the transition temperature. The shielding of the patch effect field due to contact potential differences on the inner surface of the copper tube is shown to be comparable to that of the lattice compression field. The electric field produced by an axial current in the copper tube is not shielded if the surface electrons are in local equilibrium with the metallic substrate.
Selective inhibition by phosphonoacetic acid of MDV DNA replication in a lymphoblastoid cell line

Abstract The effect of phosphonoacetic acid (PA), an inhibitor of herpesvirus DNA polymerase, was studied on replication of Marek's disease virus (MDV) DNA in a lymphoid cell line (MSB-1) originally established from an MD tumor. PA had no significant effect on the growth of MSB-1 cells at concentrations of 100 μg/ml and lower. Also, PA had no effect on synthesis of early virus antigens at concentrations up to 400 μg/ml. PA did, however, suppress the synthesis of virus specific DNA, as indicated by a decrease in the number of virus genomes per cell, and inhibited the synthesis of late virus products, as indicated by the lack of virus assembly. Minimal virus DNA was produced in cells treated with up to 400 μ/ml of PA. Removal of PA from MSB-1 cultures and further propagation of the cells in the absence of PA resulted in an increase in the number of virus genomes per cell and synthesis of late virus products.
Cooling output optimization of an air handling unit

A data-driven optimization approach for minimization of the cooling output of an air handling unit (AHU) is presented. The models used in this research are built with data mining algorithms. The performance of dynamic models build by four different data mining algorithms is studied. A model extracted by a neural network is selected for identifying the functional mapping between specific outputs and controllable and non-controllable inputs of the AHU. To minimize the cooling output while maintaining the corresponding thermal properties of the supply air within a certain range, a bi-objective optimization model is proposed. The evolutionary strategy algorithm is applied to solve the optimization problem with the optimal control settings obtained at each time stamp. The minimized AHU’s cooling output reduces the chiller’s load, which leads to energy savings.
Ensemble motion planning in trees

The problem of transporting a set of objects between the vertices of a tree by a unit capacity vehicle that travels along the edges of the tree is considered. For the case in which any object can be dropped at intermediate vertices along its route and picked up later, the authors present algorithms for finding a minimum cost transportation that run in O(k+qn) time and in O(k+n log n) time, where n is the number of vertices in the tree, k is the number of objects to be moved, and q >
Direct numerical simulations of fluid-solid systems using the arbitrary Langrangian-Eulerian technique

Abstract Since the initial publication of Hu et al. (1992, Theor. Comput. Fluid Dyn. 3 , 285), the numerical method developed for direct simulations of fluid–solid systems using the arbitrary Lagrangian–Eulerian (ALE) technique has undergone continuous modifications. Some of the modifications were described in H. H. Hu (1996, Int. J. Multiphase Flow 22 , 335). In this paper, we will present the most up-to-date implementation of the method and the results of several benchmark test problems.
Light gluino and Tevatron dijet angular distributions

Abstract We consider the effects of a light gluino on the dijet angular distributions in p p collisions at s =1800 GeV . We show that the slower running of αs and the production q q ,gg → g g do not significantly alter the normalized differential cross-sections. On the other hand, single u , d squard production qg → q g with subsequent q → q g results in dijets whose angular distributions are dramatically different from that in SM. The CDF data on dijet angular distributions with integrated luminosity of 106 pb−1 exclude u and d squarks in the mass ranges 190 ≤ m ≤ 650 and 200 ≤ m ≤ 630 GeV, respectively. We extend our analysis to lower energies and show that in a future experimental analysis for dijet mass below 240 GeV squarks will be observed or ruled out.
Magnetic nanoparticle hyperthermia enhancement of cisplatin chemotherapy cancer treatment.

AbstractPurpose: The purpose of this study was to examine the therapeutic effect of magnetic nanoparticle hyperthermia (mNPH) combined with systemic cisplatin chemotherapy in a murine mammary adenocarcinoma model (MTGB).Materials and methods: An alternating magnetic field (35.8 kA/m at 165 kHz) was used to activate 110 nm hydroxyethyl starch-coated magnetic nanoparticles (mNP) to a thermal dose of 60 min at 43 °C. Intratumoral mNP were delivered at 7.5 mg of Fe/cm3 of tumour (four equal tumour quadrants). Intraperitoneal cisplatin at 5 mg/kg body weight was administered 1 h prior to mNPH. Tumour regrowth delay time was used to assess the treatment efficacy.Results: mNP hyperthermia, combined with cisplatin, was 1.7 times more effective than mNP hyperthermia alone and 1.4 times more effective than cisplatin alone (p < 0.05).Conclusions: Our results demonstrate that mNP hyperthermia can result in a safe and significant therapeutic enhancement for cisplatin cancer therapy.
Culturing of non-brain cells in the brain ventricles

Abstract In order to find if the brain ventricles offer a viable environment for foreign cells, we have injected myocardial cells into the lateral ventricles and studied the cells by light microscopy SEM at different time periods after injection. Myocardial cells are morphologically distinctive and can be shown to be viable because they contract spontaneously. In other experiments, renin secreting kidney cells were dispersed and injected into the brain ventricles. Water intake was recorded as an index of renin secretion. We found contracting cardiac muscle cells on the ependymal wall and the same distinctively shaped cells on the walls of the lateral and third ventricle 2 or 6 weeks after transplantation. Many cells appeared to have survived the transplantation intact with smooth cell surfaces. Rats injected with kidney cells showed increased water intake. These results demonstrate the feasibility of culturing non-neuronal and neuronal hormone secreting cells in the brain ventricles for neuroendocrine studies.
The demonstration of the size principle in humans using macro electromyography and precision decomposition.

We set out to study the relationship between a motor unit's size and firing rates and its recruitment threshold and recruitment order. The data were collected from the first dorsal interosseous muscle of 11 normal subjects and analyzed using the precision decomposition and macro electromyography techniques. Our study showed that the recruitment order of a motor unit varies directly with its recruitment threshold (P < 0.00005) and that there is a progressive increase in the macro potential size of successively recruited motor units (P = 0.002). The firing rates of motor units vary inversely with their recruitment order (P = 0.006), the smaller, earlier recruited units consistently reaching higher firing rates than the larger, later recruited units. This study confirms the existence of a size principle of motor unit recruitment in humans and reveals the interactions between a motor unit's size and its firing rate properties. © 1996 John Wiley & Sons, Inc.
Derivative bibliographic relationships: the work relationship in a global bibliographic database

To contribute to the development of a sophisticated control of bibliographic works research must build on the growing understanding of the nature of the work and the constitution of bibliographic families. The present study was designed to address the following in the context of a global bibliographic database: the OCLC Online Computer Library Center's WorldCat: the proportion of works that are members of bibliographic families; the size of each family; bibliographic characteristics that can be associated with the existence or extent of derivative bibliographic relationships; the frequency with which each type of relationship appears; and the complexity of bibliographic families. A sample of bibliographic families was constructed. Results indicate that a core of works of similar character constitute the bibliographic population of American academic and research libraries (OCLC members). It seems that the canon of derivative works is greater in the academic sphere than in the bibliographic universe represented by OCLC at large. The size of a bibliographic family seems to be related to its popularity or its canonicity. Discipline, form, and genre all fail to demonstrate any influence on derivation of works. Further study of specific segments of the bibliographic universe, for instance the literature of particular disciplines, is clearly called for. The purpose of this research is to contribute to the development of a sophisticated control of bibliographic works and families. In particular, this research is designed to build on our growing understanding of the nature of the work and the constitution of bibliographic families.
Mindfulness-based interventions for binge eating: a systematic review and meta-analysis

Mindfulness-based interventions are increasingly used to treat binge eating. The effects of these interventions have not been reviewed comprehensively. This systematic review and meta-analysis sought to summarize the literature on mindfulness-based interventions and determine their impact on binge eating behavior. PubMED, Web of Science, and PsycINFO were searched using keywords binge eating, overeating, objective bulimic episodes, acceptance and commitment therapy, dialectical behavior therapy, mindfulness, meditation, mindful eating. Of 151 records screened, 19 studies met inclusion criteria. Most studies showed effects of large magnitude. Results of random effects meta-analyses supported large or medium-large effects of these interventions on binge eating (within-group random effects mean Hedge’s g = −1.12, 95 % CI −1.67, −0.80, k = 18; between-group mean Hedge’s g = −0.70, 95 % CI −1.16, −0.24, k = 7). However, there was high statistical heterogeneity among the studies (within-group I 2 = 93 %; between-group I 2 = 90 %). Limitations and future research directions are discussed.
Amine–nitrile coupling in amino-monocarbollide complexes of molybdenum

The Mo0 molybdenacarbaborane trianion [1-NH2-2,2,2-(CO)3-closo-2,1-MoCB10H10]3− is formed in situ from the reaction between [7-NH2-nido-7-CB10H10]3− and [Mo(CO)4{NH(CH2)5}2] in THF solution (THF = tetrahydrofuran). In the absence of nitriles, oxidation of this trianion by CH2CHCH2Br gives the MoII complex [1,2-μ-NH2-2,2,2-(CO)3-closo-2,1-MoCB10H10]−, isolated as its [N(PPh3)2]+ salt. However, in the presence of nitriles NCR, the same oxidation ultimately affords the species [N(PPh3)2][1,2-μ-{NHC(R)NH}-2,2,2-(CO)3-closo-2,1-MoCB10H10] in which amidine groups form a bridge between the carbon atom of the cage and the molybdenum, as a consequence of coupling of the nitrile with the cage-bound NH2 group. The acetamidine product [N(PPh3)2][1,2-μ-{NHC(Me)NH}-2,2,2-(CO)3-closo-2,1-MoCB10H10] is also formed by reaction of [7-NH2-nido-7-CB10H12]− with [Mo(CO)6] in refluxing NCMe, and its structure was confirmed by an X-ray diffraction study. Further oxidation of this species by I2 in the presence of CNBut gives the MoIV derivatives [1,2-μ-{NHC(Me)NH}-2,2-(CNBut)2-2-L-2-I-closo-2,1-MoCB10H10] (L = CO, CNBut), of which the tris(isocyanide) complex has been studied by X-ray diffraction.