cssi/SciSciGPT-SciSciNet huggingface dataset:
The completeness of MEDLINE for papers published and abstracted in the Journal of Emergency Medicine

The purpose of this paper is to assess whether MEDLINE, a common source for reviewing the medical literature, is complete with regard to referencing papers published and abstracted in The Journal of Emergency Medicine (JEM) over a 10-year period. In that time, 1178 abstracts and 843 original contributions were included in JEM. All papers were reviewed and classified as either a review of subject, case report with review of literature, editorial, or prospective or retrospective original research. Results showed 98.5% of all original work published in JEM and 99.74% of all abstracts referenced in JEM were found in MEDLINE, thus supporting the hypothesis that MEDLINE is a complete and thorough database for current literature.
Inflammatory disorders of muscle: progress in polymyositis, dermatomyositis and inclusion body myositis.

Purpose of review To provide an update on the major advances in inflammatory myopathies. Recent findings Polymyositis is an uncommon disorder that can be misdiagnosed when the old, and never validated, criteria of Bohan and Peter are used. New diagnostic criteria were recently introduced, in which the MHC/CD8 complex is considered a specific immunopathological marker because it distinguishes the antigen-driven inflammatory cells that characterize polymyositis and sporadic inclusion-body myositis from the non-specific, secondary inflammation seen in other disorders, such as dystrophies. In sporadic inclusion-body myositis the inflammatory cells invade non-vacuolated fibers, whereas the vacuolated fibers are not invaded by T cells, implying two independent processes, a primary immune process with antigen-driven T cells identical to polymyositis, and a degenerative process in which beta-amyloid and amyloid-related proteins participate in vacuolar degeneration. In polymyositis and sporadic inclusion-body myositis, antigen-specific and clonally expanded autoinvasive T cells persist for years, even in different muscles, as reconfirmed by proof-of-principle techniques involving CDR3 spectratyping combined with laser microdissected single-cell polymerase chain reaction of the T-cell receptor genes. The formation of immunological synapse between autoinvasive T cells and muscle fibers was recently strengthened by the upregulation of co-stimulatory molecules ICOS/ICOS-L and PD-L1. A new, distinct myopathy characterized by T-cell-triggered macrophage hyperactivation has now been recognized in patients with dermatomyositis-like disease. Summary Despite recent progress, the antigen(s) responsible for T-cell activation in polymyositis and sporadic inclusion-body myositis and the cause of vacuolar degeneration in sporadic inclusion-body myositis remain unclear. Newer, more aggressive immunotherapies may be encouraging, but control trials are needed to prove efficacy.
Activities of the Joint Fiber Optic Working Group (JFOWG)

It is only in the last year that deployment to the US military has occurred of a large scale production, airborne platform extensively utilizing optical fiber for data networking. This will launch the military into still broader application of optical communications to meet its ever increasing bandwidth needs. For over twenty years, the copper wiring experts have been meeting as a Wiring Action Group to identify reliability, maintainability, and availability issues. For the last five years, a sister group, the Fiber Optics Working Group, has been meeting to address similar issues, but focused on optical communications. This paper provides background on the JFOWG and clarifies the benefits that it brings to the US Navy
Workplace Safety and Health for the Veterinary Health Care Team

Veterinary clinic employers have a legal and ethical responsibility to provide a safe and healthy workplace. Clinic members are responsible for consistently using safe practices and procedures set up by their employer. Development and implementation of a customized comprehensive workplace safety and health program is emphasized, including an infection control plan. Occupational safety and health regulations are reviewed. The hazards of sharps, animal bites and scratches, and drugs are discussed. Strategies to prevent or minimize adverse health effects and resources for training and education are provided.
Two dimensional assisted liquid chromatography - a chemometric approach to improve accuracy and precision of quantitation in liquid chromatography using 2D separation, dual detectors, and multivariate curve resolution.

Abstract Comprehensive two-dimensional liquid chromatography (LC × LC) is rapidly evolving as the preferred method for the analysis of complex biological samples owing to its much greater resolving power compared to conventional one-dimensional (1D-LC). While its enhanced resolving power makes this method appealing, it has been shown that the precision of quantitation in LC × LC is generally not as good as that obtained with 1D-LC. The poorer quantitative performance of LC × LC is due to several factors including but not limited to the undersampling of the first dimension and the dilution of analytes during transit from the first dimension ( 1 D) column to the second dimension ( 2 D) column, and the larger relative background signals. A new strategy, 2D assisted liquid chromatography (2DALC), is presented here. 2DALC makes use of a diode array detector placed at the end of each column, producing both multivariate 1 D and two-dimensional (2D) chromatograms. The increased resolution of the analytes provided by the addition of a second dimension of separation enables the determination of analyte absorbance spectra from the 2 D detector signal that are relatively pure and can be used to initiate the treatment of data from the first dimension detector using multivariate curve resolution–alternating least squares (MCR–ALS). In this way, the approach leverages the strengths of both separation methods in a single analysis: the 2 D detector data is used to provide relatively pure analyte spectra to the MCR–ALS algorithm, and the final quantitative results are obtained from the resolved 1 D chromatograms, which has a much higher sampling rate and lower background signal than obtained in conventional single detector LC × LC, to obtain accurate and precise quantitative results. It is shown that 2DALC is superior to both single detector selective or comprehensive LC × LC and 1D-LC for quantitation of compounds that appear as severely overlapped peaks in the 1 D chromatogram – this is especially true in the case of untargeted analyses. We also anticipate that 2DALC will provide superior quantitation in targeted analyses in which unknown interfering compounds overlap with the targeted compound(s). When peaks are significantly overlapped in the first dimension, 2DALC can decrease the error of quantitation (i.e., improve the accuracy by up to 14-fold compared to 1D-LC and up to 3.8-fold compared to LC × LC with a single multivariate detector). The degree of improvement in performance varies depending upon the degree of peak overlap in each dimension and the selectivities of the spectra with respect to one another and the background, as well as the extent of analyte dilution prior to the 2 D column.
Restoration cutting as a management tool for regenerating Pinus banksiana after ice storm damage

Abstract In January 1998, an ice storm caused extensive and severe crown damage to the rare Pinus banksiana – P. rigida barrens in northeastern New York. These barrens contain some of the southernmost populations of P. banksiana and northernmost populations of P. rigida in the eastern US. Because P . banksiana showed particularly severe damage compared to P. rigida , and P. banksiana regeneration is absent or sparse in these stands, there is concern that P. banksiana importance may be dramatically reduced in severely damaged stands. In an attempt to reduce the risk of wildfire and to regenerate P. banksiana in such stands, restoration cuttings were completed in 1998 and 1999. Restoration cutting consisted of whole-tree harvesting (i.e. harvest of boles and attached branches) of nearly all standing trees, while branches and attached cones broken during the ice storm were left on-site as a seed source. In restoration cuttings, there were 23,400–39,800 P. banksiana seedlings/ha 2 years after harvesting, while few or no P. banksiana seedlings were observed in uncut damaged stands. P. banksiana seedling densities were several times as high in plots with evidence of soil scarification than in unscarified plots (54,000–63,600 and 12,100–30,300 P. banksiana seedlings/ha, respectively). Regeneration was positively related to cone density and negatively related to shrub and herbaceous species percent cover (e.g. R =0.30 and −0.55, respectively, for the 1999 cut), indicating the importance of even dispersal of cone-bearing slash and the reduction of competing vegetation. Restoration cutting can be used to regenerate P. banksiana in stands severely damaged by ice storms or other canopy disturbances (e.g. blowdown) if soils are adequately scarified and harvesting is conducted within a few years after canopy damage.
The Role of Behavioral Intentions in the Prediction of Behavior

Abstract Fishbein's assertion that behavioral intentions are the immediate antecedents to behavior is tested through path analysis. A sample of New York State probation officers (N = 113) completed a questionnaire which included their sentence recommendations for a period of six months (behavior); their proposed recommendations for six standardized case studies (behavioral intentions); their attitudes toward probation and incarceration (attitudes toward the act); and their beliefs about what sentences their fellow officers, supervisor, judge, and the public would prefer (social normative beliefs). The direct explanatory power of each predictor was examined, and each contributed independently to the measure of behavior. Fishbein's contentions that behavioral intentions mediate the effects of attitudes and normative beliefs was not borne out.
The Artificial Radioactivity of Copper, a Branch Reaction

The artificial radioactivity of longer half-life produced in copper by deuteron bombardment is studied. It is found to emit both electrons and positrons in the ratio 1.6 to 1. The half-life is found to be 12.8\ifmmode\pm\else\textpm\fi{}0.1 hours. The excitation curve of positrons and electrons for deuterons of different energies is studied and found to agree with the theoretical expression of Oppenheimer and Phillips. The upper limits of the energy distribution of the positrons and electrons are obtained from cloud chamber photographs, and are found to be 0.79 and 0.83 Mev, respectively. The results are interpreted as showing that this activity is due to ${\mathrm{Cu}}^{64}$ which branches in disintegrating, going either to zinc or nickel.
Matrix remodeling by MMPs during wound repair

Repair following injury involves a range of processes - such as re-epithelialization, scar formation, angiogenesis, inflammation, and more - that function, often together, to restore tissue architecture. MMPs carry out diverse roles in all of these activities. In this article, we discuss how specific MMPs act on ECM during two critical repair processes: re-epithelialization and resolution of scar tissue. For wound closure, we discuss how two MMPs - MMP1 in human epidermis and MMP7 in mucosal epithelia - facilitate re-epithelialization by cleaving different ECM or ECM-associated proteins to affect similar integrin:matrix adhesion. In scars and fibrotic tissues, we discuss that a variety of MMPs carry out a diverse range of activities that can either promote or limit ECM deposition. However, few of these MMP-driven activities have been demonstrated to be due a direct action on ECM.
The thermal radiance of clear skies

Measurements of the longwave radiance of the sky were made during the summer of 1979 at Tucson, Arizona; Gaithersburg, Maryland; and St. Louis, Missouri. The global longwave radiation (wavelengths greater than 3 μm) was monitored with a pyrgeometer and the distribution of this radiation in several spectral bands at five different zenith angles was monitored with a spectral radiometer. This paper presents results for the global sky radiation during clear sky conditions. The spectral radiometer was used to calibrate the pyrgeometer and to detect the presence of clouds. The results can most appropriately be summarized in terms of the correlation between the global sky emissivity ϵsky and surface dewpoint temperature Tdp(°C). The global sky emissivity is defined as the ratio of sky radiance to σTa4, where Ta is the absolute air temperature near the ground, and σ is the Stefan-Boltzmann constant. Based on 2945 night-time measurements in all three cities we find ϵsky=0.741 +0.0062Tdp with a standard error of estimate of 0.031. A similar relationship with almost identical coefficients holds during daylight hours.
Triazinyl chemosterilants for the house fly: 2,4-diamino-s-triazines.

Chemosterilants derived from s -triazine comprise aziridinyl alkylating agents, melamines, and 6-substituted 2,4-diamino- s -triazines. All are effective in Musca domestica L., but the aziridinyl triazines and melamines sterilize both sexes, whereas the diaminotriazines sterilize only females. Tests with 25 diaminotriazines revealed characteristic effects on the late stages of embryogenesis that were not induced by the other classes of triazines or by other types of chemosterilants. Generally, oviposition of flies treated with lowest effective dose of diaminotriazines was normal, and egg hatch was reduced only slightly; however most or all the larvae died before pupating. As an additive to the flies’ diet, 2,4-diamino-6-(2-furyl) s triazine induced such effects at concentrations as low as 2.5 ppm.
Behavioural Effects of in utero Administration of Morphine

ALTHOUGH numerous studies have been concerned with the behavioural effects of opiates, relatively little attention has been paid to the offspring of females receiving an opiate during pregnancy. The matured offspring's response to stress and to the same drug are important issues in terms of current drug abuse and potential widespread application of opiate maintenance programmes. Since morphine is readily transferred across both placental and lacteal barriers1,2, we have studied the analgesic response to morphine in the offspring of mice receiving the drug during gestation and lactation.
The Application of High Energy Density Transducer Materials to Smart Systems

Recent NUWC research efforts in the field of high power sonar transducers designed to produce high acoustic outputs over significant bandwidths while being of minimal size and weight have been aided by advances in the continuing development of several new high energy density transducer drive materials. Both Terfenol-D, a rare earth magnetostrictive material, and lead magnesium niobate, a relaxor ferroelectric, have demonstrated a tenfold increase in field-limited energy density over a typical very hard lead zirconate titanate (i.e., Clevite PZT-8) piezoelectric ceramic. The Center’s focus is to double the demonstrated performance of each material and to address such issues as hysteresis reduction in the magnetostrictive material and coupling coefficient improvements in the electrostrictive materials. Poly (vinylidene fluoride-trifluoroethylene) can also be considered a high energy density material because of its excellent energy density and its broad bandwidth possibilities. The application of these material technologies, either separately or as hybrid composites, to smart material design will be detailed.
Impact of Knowledge Support on the Performance of Software Process Tailoring

The use of a well-defined process is a widely recognized approach to increasing quality and productivity in software development. Building software processes from scratch each time is expensive and risky. Therefore, they are often created by tailoring existing processes and standards. Process tailoring is a knowledge-intensive activity. This research explores the link between knowledge support and software process tailoring performance under different levels of tailoring task complexity. It theoretically develops and tests how the fit between knowledge (generalized and contextualized) and software tailoring task complexity influences process tailoring performance. Process tailoring performance is conceptualized in terms of effectiveness and efficiency. The results from an experiment and a protocol analysis show that contextualized knowledge outperforms generalized knowledge in improving tailoring performance, and that such improvement in performance is greater in complex process tailoring tasks when compared to simple tasks.
Proton transfer and solvent reorganization in organic clusters. A theoretical study

Abstract Reaction paths for proton transfer and solvent shell reorientation, calculated for excited phenol-(NH 3 ) 5 at CIS level, are used to estimate the corresponding rate constants. Solvent reorientation is found to be barrierless and fast compared to proton tunneling, suggesting that reported nonexponential transient decays, interpreted as proton transfer followed by solvent rearrangement, may be due to proton transfer from noncommunicating states.
Zines and Zones of desire: Mass-mediated love, national romance, and sexual citizenship in Gay Indonesia

IT IS NIGHT; IN THE BACK OF A HOUSE in the city of Surabaya at the eastern end of Java is a room where two gay men complete a new edition of the zine GA Ya Nusantara (GN). At a table, Joko, one of the men, bends down over a ledger; with pen and ruler, he extends inked lines horizontally from a list of about 250 subscribers from across Indonesia, tabulating who has paid for the upcoming issue. Indra, the other man, sits before an old computer adding final touches to the new issue of the zine before sending it to a local print shop. He looks down, then up again, entering a handwritten story sent from a gay man from a small Sumatran town. All that remains is the short stack of letters from men who wish to be included in the personals section. Next to the letters lies the glossy photograph of a gay man from Bali; as this month's cover boy, his smoldering eyes will greet those who take GA Ya Nusantara into their hands. On the eastern coast of the island of Borneo, in the city of Samarinda, is a network of gay men: some hail from local Dayak and Banjar ethnic groups, and others are migrants from elsewhere in Indonesia. On this day, I am sitting in the windowless, rented room of Haru, a man from Java, when he removes a worn copy of GA Ya Nusantara from a small locked cupboard. He shares each new edition with gay friends, including Awi, an ethnic Banjar from Samarinda who lives with his sister and her husband and children. None of these family members know Awi is gay, but Awi tells
Damage to microsomal membrane by lipid peroxidation.

Alterations of microsomal membrane integrity were examined during lipid peroxidation. Loss of membrane-bound NADPH cytochromec reductase activity and protein release into the aqueous phase were related to disruption of the lipophilic region of the membrane. Formation of fluorescent products in the lipid phase of the membrane occurred only in the presence of peroxidation products. Changes in the membrane lipid phase during peroxidation included a decrease in the reactive amino groups of the phospholipids and a decrease in detectable phosphatidyl ethanolamine. In an ultrafiltration continuous flow chamber, peroxidized microsomal membranes were hydrolyzed to a lesser degree by solubilized lysosomal cathepsins and to a greater degree by lysosomal nucleases than were nonperoxidized membranes.
Rhodotorula mucilaginosa lymphadenitis in an HIV-infected patient

Summary We report a case of lymphadenitis due to Rhodotorula mucilaginosa in a man with well-controlled HIV infection. The diagnosis was established microbiologically by positive lymph tissue cultures, and clinically by responses of lymphadenitis to antifungal therapy. The patient was asymptomatic and was treated with itraconazole 200mg orally once daily as an outpatient. Clinical response was evident within three weeks with improvement of lymphadenopathy on serial computed tomography scans. Lymphadenopathy resolved completely after 8 months of itraconazole therapy and had not recurred 9 months after treatment was stopped.
Cardiac Testing to Manage Cardiovascular Risk in Cancer Patients

Cardiovascular toxicity is one of the most feared complications of cancer treatment. Recent advances in oncologic therapies have resulted in improved cancer outcomes but also a new set of cardiovascular adverse effects. Common toxicities include left ventricular dysfunction/heart failure, hypertension, and myocardial ischemia. Accurate risk stratification allows avoidance of potentially harmful treatments in those patients at greatest risk while maintaining the ability to deliver high doses of effective therapies to the lower-risk population. Cardiac investigations, including echocardiography, nuclear imaging, magnetic resonance imaging, biomarker measurement, blood pressure monitoring, electrocardiography, stress testing, and invasive angiography, can help to risk-stratify selected patients. In this review, common complications are discussed in terms of the factors used to identify patients with elevated risk, the monitoring strategies available, and selected interventions that have been used to modify outcomes in patients identified as being at high risk for cardiac complications of cancer treatment.
Local heat sink on a convectively cooled surface—application to temperature measurement error

Abstract An analysis is made of the thermal processes associated with the presence of a local heat sink (or source) on the convectively cooled surface of a solid. The sink is due to the presence of a surface-mounted thermocouple, a pin fin or other surface-mounted conductors. In the first part of the paper, heat transfer results and temperature distributions for the solid are determined in general, without reference to specific applications. The results are then applied to the case of the surface-mounted thermocouple, and the error in the measured temperature owing to the presence of the thermocouple is evaluated. Application is also made to pin fins and other surface-mounted conductors, and heat transfer rates are calculated taking into account the depression of the base temperature owing to the interaction of the fin (or conductor) and the solid. It is found that the conventional calculation which neglects the base temperature depression overestimates the heat transfer rates.
Segmented Polyurethanes: Properties as a Function of Segment Size and Distribution

Segmented polyurethanes represented by formula I are block copolymers composed of alternating soft and hard segments. They exhibit properties characteristic of crosslinked elastomers over a wide temperature range but, at higher temperatures, melt and can be processed by techniques used for plastics and fibers(1). This behavior is explained by the fact that the polymers possess a three-dimensional network built up by intermolecular association (crystallization) of the hard segments. It was therefore of interest to study the effect upon polymer properties of changes in hard segment size, distribution, and spacing along the polymer chain.
A PROSPECTIVE, RANDOMIZED STUDY ADDRESSING THE NEED FOR PHYSICAL SIMULATION FOLLOWING VIRTUAL SIMULATION

Purpose: To accurately implement a treatment plan obtained by virtual or CT simulation, conventional or physical simulation is still widely used. To evaluate the need for physical simulation, we prospectively randomized patients to undergo physical simulation or no additional simulation after virtual simulation. Methods and Materials: From July 1995 to September 1996, 75 patients underwent conformal four-field radiation therapy planning for prostate cancer with a commercial grade CT simulator. The patients were randomized to undergo either port filming immediately following physical simulation or port filming alone. The precision of implementing the devised plan was evaluated by comparing simulator radiographs and/or port films against the digitally reconstructed radiographs (DRRs) for x, y, and z displacements of the isocenter. Changes in beam aperture were also prospectively evaluated. Results: Thirty-seven patients were randomized to undergo physical simulation and first day port filming, and 38 had first day treatment verification films only without a physical simulation. Seventy-eight simulator radiographs and 195 first day treatment port films were reviewed. There was no statistically significant reduction in treatment setup error (>5 mm) if patients underwent physical simulation following virtual simulation. No patient required a resimulation, and there was no significant difference in changes of beam aperture. Conclusions: Following virtual simulation, physical simulation may not be necessary to accurately implement the conformal four-field technique. Because port filming appears to be sufficient to assure precise and reliable execution of a devised treatment plan, physical simulation may be eliminated from the process of CT based planning when virtual simulation is available.
Thermal challenge problem: Summary

This paper summarizes the approaches used to address the thermal validation challenge problem. The approaches differ in their characterization of the thermal properties and uncertainty, the definitions and use of validation metrics, the use of validation experimental data to characterize or improve the model predictions, and the assessment of regulatory compliance. All approaches estimated regulatory failure with the resulting estimated probabilities varying by an order of magnitude.
Some slip-line fields for swaging or expanding, indenting, extruding and machining for tools with curved dies

Summary Using a known solution for the expanding or swaging of a semi-circular-section hole in a semi-infinite body, attention is drawn to many related problems including that of the squashing of a pointed wedge. These plane strain solutions are then adapted for investigating indentation duo to 2- and 3-plane dies and particular solutions for indenting with curved dies are arrived at. In turn, solutions to indentation are adjusted to accommodate the cases of extrusion and simple machining with a restricted length of cutting edge. Many inverse solutions are presented—a hodograph being assumed and the physical problem it solves, then deduced.
Genomes, Gould, and Emergence

The publication of the human genome has elicited commentary to the effect that, since fewer genes were identified than anticipated, it follows that genes are less important to human biology than anticipated. The flaws in this syllogism are explained in the context of a treatise on how genomes operate and evolve and how genes function to produce embryos and brains. Most of our most cherished human traits are the result of the emergence of new properties from preexisting genetically scripted ideas, offering countless opportunities to celebrate the evolutionary process.
Malignant ovarian sex cord tumor with annular tubules in a patient with Peutz-Jeghers syndrome: a case report.

The majority of ovarian sex cord tumors with annular tubules (SCTAT) are benign neoplasms that arise sporadically. In patients who have Peutz-Jeghers syndrome (PJS), ovarian SCTAT is often an incidental finding. Malignant behavior in SCTAT has heretofore been reported only in sporadic cases. We report a case of bilateral, malignant SCTAT developing in a 47-year-old woman who had PJS, originally diagnosed as adenocarcinoma on cervicovaginal cytology. Cervicovaginal and peritoneal fluid cytologic preparations were characterized by pseudopapillary clusters and three-dimensional tubes of tumor cells with scanty cytoplasm and high nuclear:cytoplasmic ratio. Examination of surgical resection specimens revealed bilateral, solid ovarian tumors composed of simple and complex annular tubules with hyaline cores, typical of SCTAT. Tumor emboli were present within salpingeal lymphovascular spaces and in both right and left pelvic lymph nodes. Flow cytometry of tumor cells demonstrated a diploid phenotype. This case represents the first documented example of bilateral, malignant SCTAT arising in a patient who had PJS, presenting with an atypical cervicovaginal smear.
Optimization approach to 3D reconstruction from solution x-ray scattering data

Three methods for reconstructing icosahedrally-symmetric particles from solution x-ray scattering data are described. Such data is the spherical average of the magnitude-squared of the Fourier transform of the electron density in the particle and therefore is only one dimensional. Because of the limited amount of data, a priori information about the particle is crucial and the three methods differ in the description of the particle that is used. This type of reconstruction problem is important in the structural biology of spherical viruses, and example reconstructions from one such virus are described.© (1996) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Seclusion and Restraint of Children: A Literature Review

TOPIC. Nurses' attitudes toward the use of seclusion and restraint with children. PURPOSE. To review recent literature concerning these controversial interventions, and to examine possible alternative therapeutic interventions. SOURCES. Selected published nursing and psychiatric literature 1987 to 1998. CONCLUSIONS. Staff have a positive attitude toward the use of seclusion and restraint. A theory of pozoer and control may explain their use when many alternative, less restrictive interventions are available.
Regulation of matrix attachment region-dependent, lymphocyte-restricted transcription through differential localization within promyelocytic leukemia nuclear bodies.

Bright (B cell regulator of IgH transcription) transactivates the immunoglobulin heavy chain (IgH) intronic enhancer, Eμ, by binding to matrix attachment regions (MARs), sites necessary for DNA attachment to the nuclear matrix. Here we report that Bright interacts with the ubiquitous autoantigen Sp100, a component of promyelocytic leukemia nuclear bodies (PML NBs), and with LYSp100B/Sp140, the lymphoid-restricted homolog of Sp100. Both in intact cells and in nuclear matrix preparations, the majority of Bright and Sp100 colocalize within PML NBs. In contrast, Bright colocalizes with only a small fraction of LYSp100B while inducing a redistribution of the majority of LYSp100B from its associated nuclear domains (LANDs) into nucleoplasm and cytoplasm. Sp100 represses the MAR-binding and transactivation activity of Bright. LYSp100B interacts more weakly with Bright but requires significantly higher levels than Sp100 to inhibit MAR binding. However, it strongly stimulates Bright transactivation through Eμ. We suggest that Sp100 and LYSp100B interactions with Bright have different consequences for IgH transcription, potentially through differential association of Eμ MARs with nuclear matrix- associated PML NBs and LANDs.
Comparison of Traditional and Electromechanical Approaches for Structural Anthropometric Data Collection

The objective of this study was to evaluate the reliability of a new structural anthropometric measurement approach designed for those who may not have the capability to hold standardized postures. Forty-eight men and women participated in the study. Two trained researchers collected the anthropometric measurements. Twenty anthropometric dimensions were made while participants remained in a preferred or relaxed posture while seated in a wheelchair. In addition, measurements for six (6) anthropometric dimensions were repeated while participants assumed a standard seated anthropometric reference posture. Each researcher made two measurements with an electromechanical device and with an anthropometer or spreading caliper. Mean absolute differences and statistics of agreement between methods, researchers and trials were calculated for each of the anthropometric dimensions. The results of the study indicate that use of an electromechanical device may be a promising alternative to traditional methods of assessment.
The growth and development of allotransplanted neonatal canine kidneys

Abstract The postnatal growth and development of neonatal kidneys transplanted into adult recipients was studied in seven animals. An en bloc dissection including both kidneys, aorta, vena cava, and ureters was carried out in puppies 11–53 days of age and placed in the right groin of an adult recipient. The aortic segment was interposed in the right external iliac artery and proximal end of the vena cava was anastomosed to the proximal end of the common iliac vein. Ureterovesicle continuity was reestablished by ureteroneocystostomy. Immunosuppression was maintained postoperatively and the animals were serially studied by intravenous urography and renal-clearance tests. The polar diameter of the kidneys increased as much as 2-fold. Glomerular filtration rate rose from 11 ml/min at 40 days of age to 32 ml/min at 83 days of age. Over the same period effective renal plasma flow increased from 31 ml/min to 110 cc/min. On the other hand, tubular function as measured by tubular reabsorption of sodium, potassium, and phosphate per 100 ml of glomerular filtrate was normal throughout the period studied. We conclude that (1) neonatal kidneys grow and develop normally even when allotransplanted and subjected to immunosuppressive therapy, (2) renal excretory mechanisms for maintaining homeostasis are mature when corrected for GFR even at an early age, (3) neonatal kidneys can support life in an adult recipient. Neonatal kidneys, therefore, are a feasible source of donor organs for transplantation in children and adults.
Asymptotics and an asymptotic Galerkin method for hyperbolic-parabolic singular pertubation problems

A composite asymptotic expansion including initial layer corrections is developed for treating initial boundary value problems for hyperbolic equations with a small parameter multiplying the second-order time derivative term. Proof of uniform asymptotic validity is given a Hilbert space setting. The expansion forms the basis of a continuous-time Galerkin procedure for which error analysis based on the finite element method is included. This work extends recent results of Hsiao and Weinacht in two directions, one toward greater abstraction and one toward greater utility.
A Regularized Boltzmann Scattering Operator for Highly Forward Peaked Scattering

Extremely short collision mean free paths and near-singular elastic and inelastic differential cross sections (DCS) make analog Monte Carlo and deterministic computational approaches impractical for charged particle transport. The widely used alternative, the condensed history method, while efficient, also suffers from several limitations arising from the use of precomputed infinite medium distributions for sampling particle directions and energies.
The Kuroshio Extension and its recirculation gyres

This paper reports on the strength and structure of the Kuroshio Extension and its recirculation gyres. In the time average, quasi-permanent recirculation gyres are found to the north and south of the Kuroshio Extension jet. The characteristics of these recirculations gyres are determined from the combined observations from the Kuroshio Extension System Study (KESS) field program (June 2004–June 2006) and include current meters, pressure and current recording inverted echo sounders, and subsurface floats. The position and strength of the recirculation gyres simulated by a highresolution numerical model are found to be consistent with the observations. The circulation pattern that is revealed is of a complex system of multiple recirculation gyres that are embedded in the crests and troughs of the quasi-permanent meanders of the Kuroshio Extension. At the location of the KESS array, the Kuroshio Extension jet and its recirculation gyres transport of about 114 Sv. This represents a 2.7-fold increase in the transport of the current compared to the Kuroshio’s transport at Cape Ashizuri before it separates from the coast and flows eastward into the open ocean. This enhancement in the current’s transport comes from the development of the flanking recirculation gyres. Estimates from an array of inverted echo sounders and a high-resolution ocean general circulation model are of similar magnitude.
Cognitive‐Behavioral Tasks Accomplished in a Person‐Centered Relational Framework

The authors propose a person-centered relational framework in which C. R. Rogers's (1957) core conditions remain the primary catalyst of therapeutic change and cognitive-behavioral work is accomplished while adhering to person-centered principles. Important ideas asserted include the following: Cognitive-behavioral tasks occur naturally within the person-centered approach, knowledge of cognitive-behavioral theory can increase counselor empathy, and cognitive-behavioral techniques can be carefully applied within a person-centered relational framework. Finally, the person-centered relational framework with other theories is addressed.
Towards safe real-time robot teleoperation: automatic whole-sensitive arm collision avoidance frees the operator for global control

Recent results in sensor-based motion planning suggest that the collision avoidance task can be handled automatically, thus freeing the operator for global control. Whole-sensitive arm manipulators bodies are covered with a sensitive skin sensor to detect nearby objects are proposed for this purpose. The data from the sensitive skin is used with the sensor data processing and motion planning algorithms to avoid collisions for the entire robot arm body in an unknown or time-varying environment. The result is a highly efficient, safe, and robust hybrid system in which the shift motion control between the operator and the automatic system is done transparently and in real-time. The motion of the master arm is either executed faithfully, or, to avoid collisions, is used as general guidance for the slave arm. >
The role of allergy in severe asthma

The classification of asthma to identify forms which have different contributing causes is useful for all cases in which the disease requires regular treatment, but it is essential for the management of severe asthma. Many forms of the disease can occur, and complex mixtures are not uncommon; here we artificially separated the cases into four groups: (i) inhalant allergy, (ii) fungal sensitization with or without colonization (including ABPA); (iii) severe sinusitis with or without aspirin-exacerbated respiratory disease (AERD), and (iv) non-inflammatory cases, including those associated with severe obesity and vocal cord dysfunction (VCD). The reason for focusing on these groups is because they illustrate how much the specific management depends upon correct classification. Inhalant allergy can present as chronically severe asthma. However, severe attacks of asthma requiring hospital admission can occur in cases which are generally only mild or moderate. The best recognized and probably the most common cause of these acute episodes is acute infection with a rhinovirus. Recent evidence suggests that high titre IgE, particularly to dust mite, correlates to exacerbations of asthma related to rhinovirus infection. Although it is well recognized that the fungus Aspergillus can colonize the lungs and cause severe disease, it is less well recognized that those cases may not have full criteria for diagnosis of ABPA or may involve other fungi. Identifying fungal cases is important, because treatment with imidazole antifungals can provide significant benefit. Taken together, specific treatment using allergen avoidance, immunotherapy, anti-IgE, or antifungal treatment is an important part of the successful management of severe asthma, and each of these requires correctly identifying specific sensitization.
Two-Dimensional Collision in Parallel Paths

A particular case of "blind approach" is considered: that in which two vehicles travel with different speeds along parallel mean paths in a two-dimensional region. It is shown that the problem of calculating the probability of safe passage can be put in the form of equivalent zero-crossing problems for stationary, nonzero mean random processes, within a relatively long record. A lower bound for the probability of absence of zero-crossings is given in the form of a finite sum and some arguments on convergence are discussed.
A Comparative Approach to Understanding General Intelligence: Predicting Cognitive Performance in an Open-ended Dynamic Task

The evaluation of an AGI system can take many forms. There is a long tradition in Artificial Intelligence (AI) of competitions focused on key challenges. A similar, but less celebrated trend has emerged in computational cognitive modeling, that of model comparison. As with AI competitions, model comparisons invite the development of different computational cognitive models on a well-defined task. However, unlike AI where the goal is to provide the maximum level of functionality up to and exceeding human capabilities, the goal of model comparisons is to simulate human performance. Usually, goodness-of-fit measures are calculated for the various models. Also unlike AI competitions where the best performer is declared the winner, model comparisons center on understanding in some detail how the different modeling “architectures” have been applied to the common task. In this paper we announce a new model comparison effort that will illuminate the general features of cognitive architectures as they are applied to control problems in dynamic environments. We begin by briefly describing the task to be modeled, our motivation for selecting that task and what we expect the comparison to reveal. Next, we describe the programmatic details of the comparison, including a quick survey of the requirements for accessing, downloading and connecting different models to the simulated task environment. We conclude with remarks on the general value in this and other model comparisons for advancing the science of AGI development.
Lithologic control of bedrock meander dimensions in the appalachian valley and ridge province: A comment

Braun's finding that the wavelength of bedrock meanders decreases as rock hardness increases is reconciled with Hack's and Tinkler's finding that meander wavelength is greater in bedrock than alluvial channels. In populations of alluvial or bedrock channels, bank resistance controls meander wavelength via its influence on channel shape and is negatively correlated with meander wavelength. In contrast, in mixed populations of alluvial and bedrock channels, bank resistance controls meander wavelength through its effect on the recurrence interval of the channel-forming discharge and channel size and is positively correlated with meander wavelength.
Introduction of evidence-based medicine into an ambulatory clinical clerkship

Evidence-based medicine (EBM) has emerged has a critical clinical competency in the 21st century. Medical schools usually introduce students to critical appraisal in the preclinical years, but there have been few evaluated interventions in teaching EBM in the clinical years. We describe a strategy to encourage students to practice EBM during a required ambulatory medicine clerkship. During this clerkship, our students are required to submit an EBM report, which is prompted by an individual case, and structured with a 5-step approach. One small-group session is devoted to modeling this approach with a case of chest pain. Using a checklist to grade 216 consecutive EBM reports, we found that students were quite successful with the exercise, achieving on average 89.6% of possible checklist points. Students who followed the structure of the exercise closely were more likely to extend their discussions beyond that required and to suggest potential further areas of investigation or design.
Diagenesis of Sandstone/Shale Package, GCO/DOE No. 1 Well, Brazoria County, Texas: ABSTRACT

Petrographic analysis of closely spaced sandstone samples (GCO/DOE No. 1 well) of a sandstone/shale package from the Frio Formation (Oligocene) indicates that sandstone reservoir quality was influenced by shale diagenesis. Three alteration zones at increasing distance from the sandstone/shale contact are observed. This zonation may be explained as follows. Organic and inorganic maturation processes modified shale fluids which, upon expulsion into the sand, resulted in the precipitation of thin, isopachous chlorite grain coatings in the contact sand. Late in the chloritization process and thereafter, unstable framework grain silicates began to dissolve within the sand. We believe that aluminum from framework grains was removed from the contact zone by mobile organic complexes. Silica released from grain dissolution reprecipitated as quartz cement. This contact zone is about 1-ft (0.3 m) thick. As fluids passed into the second zone (about 1-ft (0.3 m) thick) the sandstone framework grain leaching continued but to a lesser degree. Kaolinite was produced from internal mass sources and from aluminum imported from the first zone. The net addition of alumina from the contact zone prevented development of quartz overgrowths in this zone and the third zone. In the third zone, dissolution of framework grain silicates was least thorough because of greater distance from the shale and alteration appears to have been aluminum conservative. End_of_Article - Last_Page 609------------
Orthogonal vector basis functions for time domain finite element solution of the vector wave equation [EM field analysis]

In this paper, the authors consider the solution of the vector wave equation for electromagnetic field analysis by a discrete time vector finite element method. The popular linear edge basis functions are augmented such that the resulting capacitance matrix is diagonal, resulting in an explicit method. The accuracy and efficiency of the method is investigated via computer experiments.
Fifteen-minute consultation: incidental findings on brain and spine imaging

Incidental findings on imaging of the brain and spine account for a large number of referrals to a paediatric neurosurgical practice. They can be cause of undue concern to the parents and can result in unnecessary investigations and interventions. This article is a review of the common pathological entities identified as incidental findings in the author's experience. The list is not exhaustive and reflects mainly the common conditions referred. Very few of these incidental findings would need surgical intervention.
Role Stress and Aggression Among Young Adults: The Moderating Influences of Gender and Adolescent Aggression

Using data provided by a panel of non-Hispanic white respondents, this study explored whether aggressive response to severe role stress during early adulthood depends on gender and on an adolescent history of aggression. Logistic regression analysis yielded these findings: Men who reported aggression during early adolescence were significantly more likely to respond to severe role stress with aggression during young adulthood, while men who were not aggressive in early adolescence did not report much increase in aggression under similar circumstances. For young women, however, role stress increased aggression only among those who did not report aggression in early adolescence. For those who reported aggression during adolescence, the effect was positive but weak. We interpret these findings using principles of socialization, gender role expectations, and social structural constraints on males and females. As part of this interpretation, we report findings of an analysis of associations among role stress, ...