cssi/SciSciGPT-SciSciNet huggingface dataset:
Coupling of concanavalin A to cellulose hollow fibers for use in glucose affinity sensor.

This article describes a method for the chemical immobilization of concanavalin A (Con A) on the inside wall of a single hollow cellulose fiber for use in glucose affinity sensor. Periodate oxidation of cellulose fiber followed by a spacer for Con A attachment was deemed to be the most optimal procedure for achieving the highest sensitivity of the sensor without compromising its physical integrity. The effects of variables like the duration of periodate oxidation and its concentration and pH of the spacer coupling step and its duration have been examined. The mechanical strength of the hollow fiber as well as its permeability to the analyte (glucose) have been evaluated prior to and after Con A coupling process. It has been demonstrated that Con A bound hollow fiber prepared according to the procedure loutlined here can be successfully used to construct glucose affinity sensor for operation in the physiological range of glucose concentrations.
Steroid-Induced Myopathy in the ICU

OBJECTIVE:To report a case of steroid-induced myopathy resulting from prolonged administration of corticosteroids in an asthmatic patient in a medical intensive care unit.CASE SUMMARY:A 30-year-old white man presented with status asthmaticus requiring intubation for respiratory failure. His hospital course was complicated by the need for reintubation and the development of “quadriplegia.” Electromyography does not identify neuropathy. After rapid tapering of systemic steroids, the patient quickly regained muscle strength, was extubated, and was transferred to a rehabilitation facility for prolonged physical therapy.DISCUSSION:Steroid-induced myopathy is a rare occurrence in the intensive care setting. Cases of myopathy that have been reported have been associated with prolonged and combined use of corticosteroids with neuromuscular blocking agents or aminoglycosides. Corticosteroids are thought to produce deleterious effects through 1 or all of 3 main pathways: altered electrical excitability of muscle fi...
Circulating microRNA as a biomarker of human growth hormone administration to patients

Circulating microRNAs (miRNAs) in plasma are being studied for use as biomarkers of specific diseases and as markers of administration of pharmaceutical agents. Administration of recombinant human growth hormone (rhGH) is prohibited by sporting authorities, but it continues to be used by athletes attempting to gain an unfair advantage in athletic competition. Current methods for detection of rhGH use rely on immunoassay technology and are limited by a short time-frame in which detection of rhGH is possible. We hypothesized that administration of rhGH would alter expression of circulating miRNAs and that any changes could be detected. To identify potential miRNA targets, we utilized miRNA microarrays for screening. Confirmatory testing used real-time reverse-transcriptase (RT) quantitative PCR (qPCR) assays of selected miRNAs in 35 plasma samples obtained from (1) individuals with no known pituitary disorders, (2) patients with excess GH production, and (3) patients receiving therapeutic replacement doses of rhGH. We identified and confirmed four miRNAs that were differentially expressed in all individuals using therapeutic replacement doses of rhGH when compared to individuals with naturally high levels of GH and normal controls. This study further develops the hypothesis that circulating miRNAs may be used as biomarkers for detection of doping in sports.
The emulation theory of representation: motor control, imagery, and perception.

The emulation theory of representation is developed and explored as a framework that can revealingly synthesize a wide vari- ety of representational functions of the brain. The framework is based on constructs from control theory (forward models) and signal processing (Kalman filters). The idea is that in addition to simply engaging with the body and environment, the brain constructs neural circuits that act as models of the body and environment. During overt sensorimotor engagement, these models are driven by efference copies in parallel with the body and environment, in order to provide expectations of the sensory feedback, and to enhance and process sensory information. These models can also be run off-line in order to produce imagery, estimate outcomes of different actions, and eval- uate and develop motor plans. The framework is initially developed within the context of motor control, where it has been shown that inner models running in parallel with the body can reduce the effects of feedback delay problems. The same mechanisms can account for motor imagery as the off-line driving of the emulator via efference copies. The framework is extended to account for visual imagery as the off-line driving of an emulator of the motor-visual loop. I also show how such systems can provide for amodal spatial imagery. Per- ception, including visual perception, results from such models being used to form expectations of, and to interpret, sensory input. I close by briefly outlining other cognitive functions that might also be synthesized within this framework, including reasoning, theory of mind phenomena, and language.
Penta-Band Planar Inverted F-Antenna (PIFA) Integrated by RF-NEMS Switches

This paper presents a novel multifunctional reconfigurable antenna (MRA) design using nano-electromechanical system (NEMS) switches. This single MRA operates over five frequency bands of GSM900, GPS1575, GSM1800, PCS1900 and UMTS2100. The reconfigurability in operating frequency is achieved by the activation of NEMS switches which are integrated within the antenna architecture. The radiation and impedance performance of the antenna was studied by using a full-wave electromagnetic simulation tool.
Personality Correlates between Need for Achievement and Subscales of the F-Scale of Authoritarianism

Summasy.--One section of data collected from an earlier, more complex experiment is examined to test the proposition that the achievement motive predicts authocitarian behavior. Particular subscales of the F-scale correlated differentially for 22 men acd 30 women with the need for achievement, supporting the notion that authoritarianism may result, in part, from an individual with a high need for achievement. Ray and Lovejoy (1983) noted that despite the perception that interest in authoritarianism has dedined, research on authoritarianism continues to be published and new scales of authoritarianism continue to be developed. In an examination of the validity of four measures of authoritarianism (the Rigby and Rump attitude of authority scale, the Hogan symbolic authoritarianism measure, the Ray Directiveness scale, and a balanced F scale) plus a need for achievement scale, Ray and Lovejoy found the need for achievement scale to be the best predictor of ratings of authoritarianism by peers familiar with the subjects' everyday and long-term behavior patterns. Ray and Lovejoy point out that this link between authoritarianism and need for achievement highlights the discrepancy between attitudes and behavior (Kelmaq 1974) and suggests that authoritarian behaviors spring not from authoritarian attitudes but from some other motivation such as need for achievement. Teevan and Hartsough (1964) examined a complex set of relations between the motivations of fear of failure and need for achievement and the degree to which they predicted scores on authoritarianism and a values scale. This analysis uses data gathered by Teevan and Hartsough (1964) and examines the theoretical relationship between need for achievement and authoritariaaism. Using data gathered from the original instruments for measuring need for achievement, the Thematic Apperception Test (McClelland, Atkinson, Clark, & Lowell, 1953) and authoritarianism, the F-scale (Adorno, et al., 1950), we reexamined the subscales of the F-scale in relation to need for achievement. The F-scale subscales are Conventionalism, Authoritarian-Submissioq Authoritarian-Aggression, Antiinuaception, Superstition and Stereotypy,
Thermal Strain Measurements in Epitaxial CoSi2/Si by Double Crystal X-Ray Diffraction

The perpendicular x-ray strain of epitaxial CoSi_2 films grown on Si(111) substrates at ∼ 600°C by MBE was measured at various temperatures. Within experimental error margins, the strain decreases linearly with rising temperature at a rate of (1.3±0.1) × 10^(-5)/°C from room temperature up to 600°C. Over that temperature range and the duration of a complete measurement (∼5h to ∼ 2h), these strain values remain reversible. At 593°C, the x-ray strain is -0.85%, which is about the strain that a stress-free CoSi_2 film on Si(111) would have at that temperature. This results show that the stress in the epitaxial CoSi_2 film is fully relaxed at the growth temperature. Strains below the growth temperature are induced in the film by the difference in the linear coefficient of thermal expansion of CoSi_2 and Si. They were calculated by assuming that the density of misfit dislocations formed at the growth temperature remains constant. The slope of the strain-temperature dependence obtained that way agrees with the measured slope if the unknown Possion ratio of CoSi_2 is assumed to be _(CoSi_2) = 0.35. A film stress of ∼ 0.8 GPa at room temperature was calculated using the above value for the Possion ratio, 130 GPa for the Young modulus, and the measured x-ray strain.
Wildlife population monitoring: some practical considerations

The accurate estimation of wildlife population density is difficult and requires considerable investment of resources and time. Population indices are easier to obtain but are influenced by many unknowns and the relationships to actual population densities are usually unclear. Wildlife biologists, whether in the public or private sector, often find themselves in difficult situations where a resource manager or landowner wants good information, quickly, at low cost, and without clear objectives. In many situations, in addition to establishing clear objectives, a budget and timeframe, a biologist must understand and deal with the reality of many logistical concerns that will make the achievement of the objectives difficult or impossible. The situation is often complicated because the biology and ecology of the species of interest may be poorly understood in the specific setting and the species may be very rare or strongly influenced by current or past human activities. Methods to monitor a wildlife population may need to be tested or validated, extending the time and resources needed to complete the assigned task. In this paper, I discuss many of the challenges faced and the decisions to be made when a biologist is requested to provide useful, timely information on the status of a wildlife population.
Assessing the benefits of NASA Category 3, low cost class C/D missions

Category 3, Class C/D missions have the benefit of delivering worthwhile science at minimal cost which is increasingly important in NASA's constrained budget environment. Although higher cost Category 1 and 2 missions are necessary to achieve NASA's science objectives, Category 3 missions are shown to be an effective way to provide significant science return at a low cost. Category 3 missions, however, are often reviewed the same as the more risk averse Category 1 and 2 missions. Acknowledging that reviews are not the only aspect of a total engineering effort, reviews are still a significant concern for NASA programs. This can unnecessarily increase the cost and schedule of Category 3 missions. This paper quantifies the benefit and performance of Category 3 missions by looking at the cost vs. capability relative to Category 1 and 2 missions. Lessons learned from successful organizations that develop low cost Category 3, Class C/D missions are also investigated to help provide the basis for suggestions to streamline the review of NASA Category 3 missions.
Effect of Temperature on the Protonation of the TALSPEAK Ligands: Lactic and Diethylenetrinitropentaacetic Acids

The protonation reactions of two ligands that play important roles in the TALSPEAK process for the separation of trivalent actinides from lanthanides, lactic acid and diethylenetrinitropentaacetic acid (DTPA), have been studied at variable temperatures. The protonation constants at 10-70 C were determined by titration potentiometry and the protonation enthalpies were determined at 25 C by titration microcalorimetry. The protonation constants remain essentially unchanged (25-70 C) within the experimental uncertainties, indicating that the effect of temperature on the protonation of lactate is insignificant. In contrast, the protonation constants of DTPA (log {beta}H's) generally decrease as the temperature is increased. Results from this study indicate that the effect of temperature on the protonation of DTPA could alter the speciation of metal ions (actinides and lanthanides) in the TALSPEAK system, since lower values of log{beta}H at higher temperatures suggest that the hydrogen ions would compete less strongly with the metal ions for the complexation of DTPA at higher temperatures.
State space modeling of dimensional variation propagation in multistage machining process using differential motion vectors

In this paper, a state space model is developed to describe the dimensional variation propagation of multistage machining processes. A complicated machining system usually contains multiple stages. When the workpiece passes through multiple stages, machining errors at each stage will be accumulated and transformed onto the workpiece. Differential motion vector, a concept from the robotics field, is used in this model as the state vector to represent the geometric deviation of the workpiece. The deviation accumulation and transformation are quantitatively described by the state transition in the state space model. A systematic procedure that builds the model is presented and an experimental validation is also conducted. The validation result is satisfactory. This model has great potential to be applied to fault diagnosis and process design evaluation for complicated machining processes.
A Gain of Superoxide Dismutase (SOD) Activity Obtained with CCS, the Copper Metallochaperone for SOD1

Abstract The incorporation of copper ions into the cytosolic superoxide dismutase (SOD1) is accomplished in vivo by the action of the copper metallochaperone CCS (copper chaperone for SOD1). Mammalian CCS is comprised of three distinct protein domains, with a central region exhibiting remarkable homology (approximately 50% identity) to SOD1 itself. Conserved in CCS are all the SOD1 zinc binding ligands and three of four histidine copper binding ligands. In CCS the fourth histidine is replaced by an aspartate (Asp200). Despite this conservation of sequence between SOD1 and CCS, CCS exhibited no detectable SOD activity. Surprisingly, however, a single D200H mutation, targeting the fourth potential copper ligand in CCS, granted significant superoxide scavenging activity to this metallochaperone that was readily detected with CCS expressed in yeast. This mutation did not inhibit the metallochaperone capacity of CCS, and in fact, D200H CCS appears to represent a bifunctional SOD that can self-activate itself with copper. The aspartate at CCS position 200 is well conserved among mammalian CCS molecules, and we propose that this residue has evolved to preclude deleterious reactions involving copper bound to CCS.
Toward Multimodal Human-Robot Cooperation and Collaboration

*† ‡ § ** †† ‡‡ §§ Our multimodal interface integrates speech recognition, natural language understanding, spatial reasoning and human cognitive models for completing specific tasks and for perspective-taking in locative oriented tasks. With natural language and gestures, we believe human-robot interaction and communication is facilitated. Instead of concentrating on the various modalities of the interface, users can concentrate on the task at hand. Likewise, by incorporating human cognitive models for handling spatial information and perspective-taking, as well as for specific task completion, a better match with the expectations that humans acquire from their human-human interactions should be obtained, further facilitating cooperation and collaboration in human-robot interactions.
The relationship between tree canopy and crime rates across an urban-rural gradient in the greater Baltimore region

a b s t r a c t The extent to which urban tree cover influences crime is in debate in the literature. This research took advantage of geocoded crime point data and high resolution tree canopy data to address this question in Baltimore City and County, MD, an area that includes a significant urban-rural gradient. Using ordinary least squares and spatially adjusted regression and controlling for numerous potential confounders, we found that there is a strong inverse relationship between tree canopy and our index of robbery, burglary, theft and shooting. The more conservative spatially adjusted model indicated that a 10% increase in tree canopy was associated with a roughly 12% decrease in crime. When we broke down tree cover by public and private ownership for the spatial model, we found that the inverse relationship continued in both contexts, but the magnitude was 40% greater for public than for private lands. We also used geographically weighted regression to identify spatial non-stationarity in this relationship, which we found for trees in general and trees on private land, but not for trees on public land. Geographic plots of pseudo-t statistics indicated that while there was a negative relationship between crime and trees in the vast majority of block groups of the study area, there were a few patches where the opposite relationship was true, particularly in a part of Baltimore City where there is an extensive interface between industrial and residential properties. It is possible that in this area a significant proportion of trees is growing in abandoned lands between these two land uses.
Tetracycline Therapy: Update

Tetracyclines have been used for treatment of a wide variety of gram-positive and gram-negative bacterial infections since the 1950s. In addition to being effective against traditional bacteria, tetracyclines have been used to treat infections due to intracellular chlamydiae, mycoplasmas, rickettsiae, and protozoan parasites and a variety of noninfectious conditions. They are important for treatment of and prophylaxis against infections with bacteria that could be used in biological weapons. Bacterial resistance to tetracycline was identified shortly after the introduction of therapy. At present, tetracycline resistance in bacteria can occur by acquisition of >or=1 of the 36 different genes, by mutations to host efflux pumps or in their 16S rRNA sequences, or by alteration in the permeability of the cell. In contrast, tetracycline resistance has not yet been described in protozoa or other eukaryotic organisms.
A single-LC-tank 5–10 GHz quadrature local oscillator for cognitive radio applications

This paper presents a local oscillator (LO) that converts oscillation frequencies of 13.3–20GHz from a single-LC-tank VCO to the intended 5–10GHz with continuous frequency coverage. A 4-stage differential injection-locked ring oscillator (ILRO) is used after the latch-based divider to produce quadrature output phases without requiring 50% duty cycle of input signals as those of conventional divide-by-2 approaches. When implemented in 65nm CMOS, the prototype LO consumes 22mA at 1V supply and is able to exhibit a worst-case phase noise of −102dBc/Hz at 1MHz offset across the entire 5–10GHz band for projected cognitive radio applications.
Ethiopia: a Survey on the Existence of a Feudal Peasantry

As towns, industries, agricultural developments, and the green revolution come to Africa, social theorists are beginning to write about the emergence of a peasant class. In addition, they are relating the concept of a peasantry to the growing patterns of capitalism and socialism which are to be found throughout the continent, albeit for the most part asserting that contemporary social systems are built on tribal rather than feudal foundations. What is remarkable from this perspective is that as Africanists turn their attention to these issues, and discuss rigorous conceptual problems regarding the terms ‘peasant’ and ‘feudal’, they continue to be almost unaware of Ethiopia.
Kinetic inductance parametric up-converter

We describe a novel class of devices based on the nonlinearity of the kinetic inductance of a superconducting thin film. By placing a current-dependent inductance in a microwave resonator, small currents can be measured through their effect on the resonator’s frequency. By using a high-resistivity material for the film and nanowires as kinetic inductors, we can achieve a large coefficient of nonlinearity to improve device sensitivity. We demonstrate a current sensitivity of 8pA/√Hz, making this device useful for transition-edge sensor (TES) readout and other cutting-edge applications. An advantage of these devices is their natural ability to be multiplexed in the frequency domain, enabling large detector arrays for TES-based instruments. A traveling-wave version of the device, consisting of a thin-film microwave transmission line, is also sensitive to small currents as they change the phase length of the line due to their effect on its inductance. We demonstrate a current sensitivity of 5pA/√Hz for this version of the device, making it also suitable for TES readout as well as other current-detection applications. It has the advantage of multi-GHz bandwidth and greater dynamic range, offering a different approach to the resonator version of the device.
Civil Procedure Reform in Switzerland and the Role of Legal Transplants

On January 1, 2011, Swiss courts will begin operating under a unified federal code of civil procedure for the first time in the country’s history. This code has been exceedingly long in the making. In this chapter, I use the new code and its history to engage the editors’ claim that the old categories of common law and civil law procedure are crumbling, thus making differences among countries within the common law or civil law world more important than differences across the divide.First, the new Swiss code of civil procedure includes a number of features that may look like they were borrowed from the common law world or, more succinctly, from the United States. Yet, they have long been features of the codes of some Swiss cantons, partly originating in Switzerland itself, partly borrowed centuries ago from neighboring countries. Perhaps then, the distinction between common law and civil law procedure has never been as clear-cut as some accounts would have it. Second, the new Swiss Code almost entirely eschews borrowing from foreign legal systems, common law or civil law. In examining the reasons for this lack of borrowing, I attempt to identify possible circumstances under which borrowing is likely to occur and when it is not. I conclude that the operating assumption of any project of procedural reform is going to be to refrain from borrowing unless particular countervailing forces prevail. Thus, I do not think that the distinction between common law and civil law is likely to disappear soon. Neither, however, do I think the distinction has ever been as pronounced as is often assumed.
In Vivo 13 C Magnetic Resonance Spectroscopy and Metabolic Modeling: Methodology

In vivo 13C NMR spectroscopy combined with infusion of 13C-enriched substrates allows non-invasive investigation of brain metabolism in animals and humans. Time courses of 13C label incorporation from the infused substrate(s) into brain metabolites can be analyzed with metabolic models to quantify metabolic rates through specific metabolic pathways such as the neuronal and glial TCA cycles, pyruvate carboxylase, or the glutamate-glutamine cycle. In this chapter, we review the methodology for successful in vivo 13C MRS measurements and metabolic modeling studies. The various aspects of this methodology are described with a focus on challenges specific to in vivo measurements in the brain. References in this review are current as of March 2008.
The Effect of Group Attitude Diversity and Attitude Strength on Subsequent Cooperation

Groups often have members who hold opposing opinions on specific issues. The presence of undecided people within a group may promote cooperation among group members who hold opposing views on an issue under consideration. The study examined the joint effects of group attitude diversity (i.e. mixed attitude diversity vs. polarized attitude diversity) and one’s strength of attitude on the cooperation. In groups considering a controversial issue with no undecided group members (i.e. polarized attitude diversity), people with strong attitudes were less likely than those with weak attitudes to cooperate with group members who held opposing views. However, the above differences became non-significant when participants were placed in groups with some undecided group members (i.e. mixed attitude diversity). The results from the study suggested that the presence of undecided group members mitigates the negative impact of attitude strength on subsequent cooperation.
Donnan Potentials Generated by the Surface Charge on Muscle Filaments

Electrochemical potentials (measured with microelec-trodes) in the liquid-crystalline lattices of striated muscle result from Donnan equilibriums established by the fixed charge associated with the myosin rods and actin filaments in the ionic cytosol. From these electrochemical potentials and the unit-cell volumes (measured by x-ray diffraction) together with Donnan theory, the effective linear charge densities are derived for the respective myosin rods and actin filaments. Electrochemical potentials also were measured under conditions that varied the parameters of the Donnan equation. Modeling predicted Donnan potentials for the same conditons. The predicted Donnan potentials correlate well with the measured electrochemical potentials for both the A-band and I-band liquid-crystalline lattices.
Unnecessary lipid-lowering drugs in an outpatient geriatric clinic.

OBJECTIVES Identify the number of patients in the University of Colorado Seniors Clinic who were prescribed a nonstatin lipid-lowering therapy and describe a pharmacist intervention that can reduce the unnecessary use of these agents. SETTING Outpatient geriatrics clinic in a university health system. PRACTICE DESCRIPTION The University of Colorado Seniors Clinic provides outpatient care for ambulatory patients 75 years of age or older. In 2012, there were 2,000 active patients, with 7,000 clinic visits. PRACTICE INNOVATION All patients prescribed extended-release niacin, ezetimibe, fenofibrate, gemfibrozil, or prescription omega-3-acid ethyl esters were identified. Extended-release niacin, ezetimibe, fenofibrate, and gemfibrozil were deemed necessary if the patient was intolerant to statin therapy or could not attain the cholesterol goal with the maximum tolerated dose of a statin. Fenofibrate, gemfibrozil, and prescription omega-3-acid ethyl esters were considered necessary if the patient had a history of triglycerides above 500 mg/dL. If a pharmacist deemed the medication unnecessary, a note was placed in the medical record and discussed face-to-face with the provider. MAIN OUTCOME MEASURE(S) The number of patients and types of drugs that were prescribed and discontinued; the cost savings to the health system. RESULTS Fifty-five patients were prescribed a potentially unnecessary lipid-lowering drug. Twenty-three drugs were discontinued, for an estimated $38,660.40 in cost savings. CONCLUSIONS A low percentage of patients were prescribed a nonstatin lipid-lowering agent in this population. However, more than half were deemed unnecessary and were stopped, resulting in significant savings and health benefits. Applying this on a larger scale could result in significant savings and improved health.
Design and Deviance: Patent as Symbol, Rhetoric as Metric, Part 1

This project reveals the power of gender and sexuality norms in the deep discourse of pivotal American case law on design patents. In Part 1 (Summer 2015), I show that late nineteenth-century cultural developments in the urban Northeast gave rise to a stigma surrounding the "ornamental" and "decorative" works under the then-exclusive legal purview of design-patent protection. Among the politically dominant segments of American society, the creation, appreciation, and consumption of design "for its own sake" grew increasingly intertwined with notions of decadence, effeminacy, and sexual "deviance." In Part 2 (forthcoming Feb. 2016), I will examine influential design-patent decisions from the 1870s through the 1930s against this cultural backdrop. My close reading of these decisions will demonstrate that federal judges, particularly in leading cases decided by the Second Circuit, increasingly used design-patent disputes as a vehicle for the performance and endorsement of prevailing gender norms. The resulting doctrine relegated design patents to near-total irrelevance as a viable form of intellectual property protection for a large and crucial portion of the Twentieth Century. [In a forthcoming monograph, "Patents and Perverts: The Hidden Moral Agenda of American Design Law" (Cambridge University Press forthcoming 2017), I will examine doctrinal distortions in U.S. copyright and trademark law that resulted from the judiciary's marginalization of design patents. Some of these distortions, including the perpetually problematic doctrines of "conceptual separability" and "aesthetic functionality," persist to this day -- even as an array of jurisprudential, social, and economic factors have facilitated the reemergence of design patents as a viable form of IP protection.]
Acquired Multiple Cysts of the Kidney in Neuroblastoma Survivors

Cystic kidney disease includes a wide range of hereditary, developmental, and acquired conditions of the kidneys. Some of the inherited causes of cystic kidney disease include autosomal dominant polycystic kidney diseases (caused by mutations in PKD1 or PKD2), autosomal recessive polycystic kidney disease, tuberous sclerosis complex, von Hippel-Lindau disease, oral-facial-digital syndrome type I, and Hadju-Cheney syndrome. Acquired cystic kidney disease has been reported in patients receiving long-term hemodialysis or peritoneal dialysis and in children after liver transplantation. Acute kidney injury can occur in patients with neuroblastoma, usually as a result of thrombotic microangiopathy associated with bone marrow transplantation. End-stage renal disease is described in long-term survivors. However, in this case report, we provide what is to our knowledge the first description of multiple kidney cysts in long-term survivors of stage IV neuroblastoma. None of the 7 patients we describe with neuroblastoma and multiple kidney cysts had a family history of autosomal dominant polycystic kidney disease. Also, all lacked stigmata of tuberous sclerosis complex, von Hippel-Lindau disease, or Hadju-Cheney syndrome. Two patients progressed to end-stage renal disease; in addition, one of them developed an oncocytoid renal cell carcinoma.
Evaluation of clinical experiences in nursing education.

Study identified items to measure two dimensions of teaching-learning experiences in clinical education, Clinical Impact and Accountability.
The systemic lupus erythematosus travel burden survey: baseline data among a South Carolina cohort

Many studies on the impact of systemic lupus erythematosus or lupus have identified patient travel costs as being problematic. We administered a survey that examined the impact of self-rated travel burden on lupus patients. The systemic lupus erythematosus travel burden survey included 41 patients enrolled in the systemic lupus erythematosus database project at the Medical University of South Carolina. Most participants reported that travel caused medications to be discontinued or appointments to be missed. In unadjusted logistic regressions of the relationship between these outcomes and medical travel burden, both distance to rheumatologists and time to lupus medical care were significant. Our findings suggest that more research is needed to examine the influence of travel burden among this population, but data from this report could help to inform physicians, academic researchers, and other health professionals in South Carolina and other areas with significant rural populations on how travel burden may impact patients receiving care for lupus and provide an opportunity for the development of interventions aimed at assisting lupus patients with management of stressors related to travel burden.
Inclusive science education: learning from Wizard

This case study reports on a student with special education needs in an inclusive seventh grade life science classroom using a framework of disability studies in education. Classroom data collected over 13 weeks consisted of qualitative (student and classroom observations, interviews, student work samples and video-taped classroom teaching and learning record using CETP-COP) methods. Three key findings emerged in the analysis and synthesis of the data: (1) The learning experiences in science for Wizard are marked by a dichotomy straddled between autonomy [“Sometimes I do” (get it)] and dependence [“Sometimes I don’t (get it)], (2) the process of learning is fragmented for Wizard because it is underscored by an emerging disciplinary literacy, (3) the nature of the inclusion is fragile and functional. Implications for classroom practices that support students with learning disabilities include focusing on student strengths, intentional use of disciplinary literacy strategies, and opportunities for eliciting student voice in decision making.
Research on oxidation kinetics of tight oil from Wolfcamp field

ABSTRACTThermogravimetry and differential scanning calorimetry were performed on a tight oil that was collected from the Wolfcamp shale reservoir, USA. The results indicate that although the oil has similar properties to those of a light oil, it shows similar thermal-oxidative behaviors to those of a heavy oil. Kinetic data of the tight oil as activation energy and frequency factor were estimated by the Arrhenius method. This kinetic analysis could provide us insight to characterize the reactivity of the tight oil, and establish parameter values for kinetic models used in the numerical simulation of the air injection process.
Orthodox Models for Adjustment and Growth

Macroeconomic imbalances arising both from external shocks and from inappropriate domestic policies repeatedly confront developing countries with the need to restore domestic and external balance. Adjustment programs, often supported by the resources of the International Monetary Fund (IMF) and the World Bank, are designed to simultaneously achieve both objectives. Because these institutions have attached conditions to their provision of financial assistance in support of such programs, their roles in influencing the design of adjustment, resulting in so-called “orthodox” adjustment, have often proven to be controversial. Orthodox adjustment, of course, is often undertaken outside the context of Fund or Bank-supported programs. More broadly, the term applies to an approach to adjustment which relies heavily on the market mechanism, on “getting prices right”, and on restrictive financial policies.
The State, Globalization and Phases of Capitalist Development

The quarter century following the end of the Second World War is often called the Golden Age of capitalism, in light of the relatively rapid and stable economic growth in the major industrialized capitalist countries in that period. However, that was by no means the only long period of relative prosperity in world capitalist history. Two others that have been identified ran from the mid-1840s to the mid-1870s and the mid-1890s to 1913 (Mandel 1975: 122; Gordon et al. 1982: 9). The intervals between these vigorous long-term expansions have seen poorer economic performance by a variety of measures. This alternation between long periods of rapid growth and long periods of slow or no growth has led some analysts to refer to ‘long swings’ in capitalist economies.1
Disruption of gel phase lipid packing efficiency by sucralose studied with merocyanine 540

Sucralose, an artificial sweetener, displays very different behavior towards membranes than its synthetic precursor sucrose. The impact of both sugars on model dipalmitoylphosphatidylcholine model membranes was investigated using absorbance and flourescence spectroscopy and the membrane probe merocyanine 540. This probe molecule is highly sensitive to changes in membrane packing, microviscosity and polarity. This work focuses on the impact of sugars on the outer leaflet of unilamellar dipalmitoyl phosphatidylcholine model membranes. The choice of lipid permits access to the gel phase at room temperature and incorporation of the dye after liposome formation allows us to examine the direct impact of the sugar on the outer leaflet while maximizing the response of the dye to changes in the bilayer. The results demonstrate that sucrose has no impact on the packing efficiency of lipids in unilamellar DPPC vesicles in the gel phase. Conversely sucralose decreases the packing efficiency of lipids in the gel phase and results in decreased microviscosity and increased membrane fluidity, which may be as a result of water disruption at the membrane water interface.
Outcomes of young patients with Waldenstrom macroglobulinemia (WM).

8609 Background: WMis infrequentin young population, and data in patients (pts) ≤50 years of age are sparse. We present outcomes of a large cohort of young WM pts seen at Mayo Clinic, Rochester bet...
A Behavioral Theory of Real Options

Strategic investment decisions often involve substantial uncertainty. Real options theory suggests a decision logic emphasizing the value of small initial investments that provide the opportunity t...
Program level of nursing students and the achievement of intercultural sensitivity after service learning experiences

Nursing students require education and experience to develop cultural competence. Cultural sensitivity is a step on the journey to cultural competence. Nursing curricula vary regarding when and how to promote cultural sensitivity. Service learning (SL), is an experiential pedagogical method, which provides the opportunity to communicate and interact with persons from various cultures. A descriptive pilot study was undertaken in order to examine whether the program level affects the intercultural sensitivity of nursing students exposed to SL. The original Intercultural Sensitivity Scale (ISS) was used to assess intercultural sensitivity. In a paired samples t test, two statements in the ISS relating to Interaction Confidence ( p = .006) and Respect for Cultural Differences ( p = .002) demonstrated junior level students had increased intercultural sensitivity scores when compared with sophomore level students’ scores. This study may provide guidance to nursing faculty in determining at which level of students who will have maximal gain from SL.
Venous System Interventions for Device Implantation

Subclavian obstruction is common after lead implantation and the need to add or replace a lead is increasing. Subclavian venoplasty (SV) is a safe and effective option for venous occlusion. Peripheral venography overestimates the severity of the obstruction. A wire can usually be advanced into the central circulation for SV. Compared with dilators, SV improves the quality of venous access, providing unrestricted catheter manipulation for His bundle pacing and left ventricular lead implantation. SV preserves venous access and reduces lead burden. SV can easily be added to the implanting physicians lead management options.
The plantation and the mine: Comment on “After the land grab: Infrastructural violence and the ‘mafia system’ in Indonesia’s oil palm plantation zone” by Tania Li

Abstract This paper is a commentary on Tania Li's paper, “After the land grab: Infrastructural violence and the 'mafia system' in Indonesia's oil palm plantation zone.” In her paper, Tania Li considers plantations as a spatial, politico-economic and socionatural assemblage. Drawing on her recent work on African palm plantations in Indonesia, Li asks not only what is lost with the establishment of plantation, but also and perhaps more importantly, what is newly produced? The present paper notes the striking similarities between plantations and mines as territorialized sites of capital accumulation conditioned on radical ecological and social simplification.
Pragmatism and Practicality: Rethinking U.S. Civil–Military Relations Models for a Turbulent Era

In his recent article Saving Samuel Huntington and the Need for Pragmatic Civil–Military Relations, Travis proposes a model of civil–military relations based on “pragmatic civilian control.” This m...
The Practice Gap in Health Care Transition: Focus on Young People Heading to College with a Mental Health Condition

Planned health care transition for young people with special health care needs, including those with emotional, behavioral, and developmental disorders, has been deemed a health priority both here in the U.S. and abroad. However, gaps in health care transition services for adolescents and young adults continue to exist. Youth headed to college with pre-existing mental health conditions are among those in need of transition preparation and planning services. When compared to their peers without mental illness, these students face additional challenges when transitioning to college. They must have some understanding of how their illness might impact functioning in the college environment and what supports they need to aid academic and social success. They are expected to manage their illness more independently, advocate for themselves, develop relationships with new treatment providers, and navigate a new system of care. In this chapter, the definition and goals of health care transition are described. Then, by looking at the prevalence of mental health disorders in the college-age population in conjunction with recent college enrollment statistics, findings from developmental psychopathology, and survey data of incoming freshman, the scope of the need for mental health care transition services for college-bound youth is highlighted. Knowledge of normal child, adolescent, young adult, and family development, the principles of the systems of care model, tenets of educational transition planning, and anticipatory guidance, along with clinical experience and expert consensus, inform best practices in mental health care transition planning.
Video quality assessment accounting for temporal visual masking of local flicker

Abstract An important element of the design of video quality assessment (VQA) models that remains poorly understood is the effect of temporal visual masking on the visibility of temporal distortions. The visibility of temporal distortions like local flicker can be strongly reduced by motion. Based on a recently discovered visual change silencing illusion, we have developed a full reference VQA model that accounts for temporal visual masking of local flicker. The proposed model, called Flicker Sensitive-MOtion-based Video Integrity Evaluation (FS-MOVIE), augments the well-known MOVIE Index by combining motion tuned video integrity features with a new perceptual flicker visibility/masking index. FS-MOVIE captures the separated spectral signatures caused by local flicker distortions, by using a model of the responses of neurons in primary visual cortex to video flicker, an energy model of motion perception, and a divisive normalization stage. FS-MOVIE predicts the perceptual suppression of local flicker by the presence of motion and evaluates local flicker as it affects video quality. Experimental results show that FS-MOVIE significantly improves VQA performance against its predecessor and is highly competitive with top performing VQA algorithms when tested on the LIVE, IVP, EPFL, and VQEGHD5 VQA databases.
Effects of Lasers on Biologic Tissue: Options for Specificity

In any tissue most biologic effects of optical radiation are usually caused by either or both of two basic mechanisms: (1) responses to photochemical reactions, and (2) responses to the heat caused by non-radiative deexcitation and dissipation of the absorbed energy. Host responses to extensive photochemical cell injury are not qualitatively very different from the inflammation and repair which occur from injury by many physical and chemical agents. However, in the case of more subtle cell alterations, the inherent specificity of photochemical reactions may lead to quantitative differences in host response to various wavelengths. In fact many biological responses to in vivo photochemical reactions can be very wavelength-dependant and quite specific. In vivo extracellular photochemical reactions may also have very specific effects on the host.
Performance of the CURB-65 Score in Predicting Critical Care Interventions in Patients Admitted With Community-Acquired Pneumonia.

Study objective Confusion, uremia, elevated respiratory rate, hypotension, and aged 65 years or older (CURB-65) is a clinical prediction rule intended to stratify patients with pneumonia by expected mortality. We assess the predictive performance of CURB-65 for the proximal endpoint of receipt of critical care intervention in emergency department (ED) patients admitted with community-acquired pneumonia. Methods We performed a retrospective analysis of electronic health records from a single tertiary center for ED patients admitted as inpatients with a primary diagnosis of pneumonia from 2010 to 2014. Patients with a history of malignancy, tuberculosis, bronchiectasis, HIV, or readmission within 14 days were excluded. We assessed the predictive accuracy of CURB-65 for receipt of critical care interventions (ie, vasopressors, large-volume intravenous fluids, invasive catheters, assisted ventilation, insulin infusions, or renal replacement therapy) and inhospital mortality. Logistic regression was performed to assess the increase in odds of critical care intervention or inhospital mortality by increasing CURB-65 score. Results There were 2,322 patients admitted with community-acquired pneumonia in the study cohort; 630 (27.1%) were admitted to the ICU within 48 hours of ED triage and 343 (14.8%) received a critical care intervention. Of patients with a CURB-65 score of 0 to 1, 181 (15.6%) were admitted to the ICU, 74 (6.4%) received a critical care intervention, and 7 (0.6%) died. Of patients with a CURB-65 score of 2, 223 (27.0%) were admitted to the ICU, 127 (15.4%) received a critical care intervention, and 47 (5.7%) died. Among patients with CURB-65 score greater than or equal to 3, 226 (67.0%) were admitted to the ICU, 142 (42.1%) received a critical care intervention, and 43 (12.8%) died. The areas under the receiver operating characteristic for CURB-65 as a predictor of critical care intervention and mortality were 0.73 and 0.77, whereas sensitivity of CURB-65 score greater than or equal to 2 in predicting critical care intervention was 78.4%; for mortality, 92.8%. Conclusion Patients with CURB-65 score less than or equal to 2 were often admitted to the ICU and received critical care interventions. Given this finding and the relatively low sensitivity of CURB-65 for critical care intervention, clinicians should exercise caution when using CURB-65 to guide disposition. Future ED-based clinical prediction rules may benefit from calibration to proximal endpoints.
Abstract TP80: Improving Perioperative Stroke Detection During Intracranial Aneurysm Surgery Using Somatosensory Evoked Potential Waveform Analysis

Background: Current alarm criteria for evaluating impending perioperative stroke using somatosensory evoked potential (SSEP) intraoperative monitoring is a 50% reduction in amplitude or a 10% incre...