cssi/SciSciGPT-SciSciNet huggingface dataset:
A vortex-lattice method for the calculation of the nonsteady separated flow over delta wings.

An analysis is made of the wake structure and the forces on a delta wing as it undergoes nonsteady motion, wherein the flow separates at the leading edge. Comparisons of these predictions with existing experimental and theoretical data for the nonsteady linear and nonlinear motions indicate good agreement. It was found that the time-dependent, wake-shedding numerical procedure applied here for the wake rollup and the lift force calculation resulted in considerable saving of computer time over methods using the iterative wake rollup procedure. Calculated results for various motions of the delta wing, including the plunging motion, are presented for both the separated and the attached flow cases.
Alkaline Phosphonionoesterase Activity in Insects. 2. Activity in Various Cell Fractions from the Blow Fly Phormia regina12

The alkaline phosphomonoesterase activity of mitochondrial, microsomal, and soluble fractions prepared from Phormia regina (Meigen) were investigated, and the enzymes were partially purified. The alkaline phosphomonoesterases of these cell fractions are similar in pH optimum, metal ion activation, and stability in the presence and absence of substrate. Minor differences exist in the Michaelis constants, when p -nitrophenyl is used as the substrate, and in their substrate specificity. Manganese and magnesium are the most effective activators of several tested, and, in contrast to the corresponding enzymes in vertebrates, neither copper nor organic sulfhydryl binding agents are effective inhibitors.
Culture and identification of neural precursor cells from subependymal region of adult Macaca fascicularis

Objective To isolate and culture neural precursor cells from subependymal region of adult Macaca fascicularis and to study their biological properties.Methods The tissue from subependymal region of adult Macaca fascicularis was digested in papain and DNase,screened through 300-mesh filter,then seeded into DMEM-F12 medium containing EGF and bFGF.Results Precursor cells could proliferate into neurospheres while neurons and glia died at the same time.Precursor cells, positive for nestin but negative for GFAP,were not the stem cells observed in subependymal region in vivo. Precursor cells underwent self-differentiation in DMEM-F12 without growth factors.Differentiated cells expressed astrocyte marker-GFAP and neuron marker-Tuj-1.Conclusion Cells from subependymal region of adult Macaca fascicularis showed some characteristics of neural precursor cells,including the ability to proliferate into neurospheres and to differentiate into neurons and glial cells.
Acre by Acre: Providing Standards for Agricultural Mitigation Using Agricultural Conservation Easements

II. THE CALIFORNIA ENVIRONMENTAL QUALITY ACT REQUIRES MITIGATING ENVIRONMENTAL IMPACTS 216 A. Analysis of Mitigating Significant Environmental Impacts 217 B. Conservation Easements as a Mitigation Measure for CEQA Compliance 218
Managerial Implications of Perceptions, Knowledge, Attitudes, and Awareness of Residents Regarding Puerto Morelos Reef National Park, Mexico

ABSTRACT Heinen, J.T.; Roque, A., and Collado-Vides, L., 2017. Managerial implications of perceptions, knowledge, attitudes, and awareness of residents regarding Puerto Morelos Reef National Park, Mexico. This study explores the perceptions of local residents of Puerto Morelos, Quintana Roo, Mexico, concerning Puerto Morelos Reef National Park using semistructured and key informant surveys. Collectively, the data provide qualitative and quantitative information regarding attitudes, knowledge, and awareness of park regulations and natural resources, as well as opinions about the formation and management of the protected area. The results show large differences in knowledge and awareness based on location of households within the community. Demographic indicators including education level, nationality, and length of community residence significantly correlate with perceptions about marine protection. There was a significant relationship between awareness of economic growth provided by the protected area and...
Emotional intelligence and job performance: The mediating role of work-family balance

In this study, we examine the dynamics between emotional intelligence, work-family balance, and job performance. A review of the literature to date has shown distinct relationships between emotional intelligence to job performance and work-family balance to job performance. We utilize a sample of 233 respondents to empirically test our set of hypotheses that contend work-family balance mediates the relationship between emotional intelligence and job performance. Our results support these hypotheses. Practical implications and directions for future research are discussed.
Dracula and Gothic Tourism

“Ages ago a savage mode of keeping accounts on notched sticks was introduced into the Court of the Exchequer,” noted Charles Dickens, referring to a common method of recording debt that had been used since the Middle Ages. Employed especially in agrarian taxation, the split tally stick had finally, in 1825, given way to modern forms of record keeping using pen, ink, and paper. By 1834, these sticks and stocks constituted a vast accumulated archive that was no longer required and had to be destroyed. It came to pass that they were burnt in a stove in the House of Lords. The stove, overgorged with these preposterous sticks, set fire to the panelling; the panelling set fire to the House of Lords; the House of Lords set fire to the House of Commons; the two houses were reduced to ashes; architects were called in to build others; we are now in the second million of the cost thereof.1
Fracking in Africa

Substantial environmental concerns have accompanied the shale boom in developed countries where the vast majority of fracking has occurred to date. There is more reason for concern in the developing world where nations enjoy far less governance capacity. This chapter presents a conceptual framework to address the governance situation in developing countries confronting hydraulic fracturing. The framework is applied to South Africa and Botswana, where shale exploration has recently begun in earnest. The chapter clarifies the governance capacity of these countries, as well as areas where institutional and regulatory quality can be improved in order to increase prospects for sustainable hydraulic fracturing.
Nursing Students' Perceptions of Learning Psychomotor Skills: A Literature Review

Abstract The aim of this qualitative literature review was to answer the question, "What are nursing students' perceptions of learning psychomotor skills?" After reviewing 96 studies from 1980 to June 2016, 6 studies met inclusion criteria. Six themes were identified: peers are important; practice on real people; faculty members matter; environment is essential; patients need my skills; and anxiety is ever present. Faculty members can use these findings to better understand students' experiences when learning psychomotor skills.
New stopping criteria for spectral partitioning

Spectral partitioning (clustering) algorithms use eigenvectors to solve network analysis problems. The relationship between numerical accuracy and network mining quality is insufficiently understood. We show that analyzing numerical accuracy and network mining quality together leads to an algorithmic improvement. Specifically, we study spectral partitioning using sweep cuts of approximate eigenvectors of the normalized graph Laplacian. We introduce a novel, theoretically sound, parameter free stopping criterion for iterative eigensolvers designed for graph partitioning. On a corpus of social networks, we validate this stopping criterion by showing the number of iterations is reduced by a factor of 4.15 on average, and the conductance is increased by only a factor of 1.24 on average. Regression analysis of these results shows that the decrease in the number of iterations needed is greater for problems with a small spectral gap, thus our stopping criterion helps more on harder problems. Experiments show that alternative stopping criteria are insufficient to ensure low conductance partitioning on real world networks. While our method guarantees partitions that satisfy the Cheeger Inequality, we find that it typically beats this guarantee on real world graphs.
Electrical anisotropy and coexistence of structural transitions and superconductivity in IrT e 2

We report experimental investigations of the electrical transport, magnetic, and thermodynamic properties of $\mathrm{IrT}{\mathrm{e}}_{2}$ single crystals. The resistivity, magnetization, and specific heat display anomalies at ${T}_{\mathrm{S}1}\ensuremath{\approx}283\phantom{\rule{0.16em}{0ex}}\mathrm{K},{T}_{\mathrm{S}2}\ensuremath{\approx}167\phantom{\rule{0.16em}{0ex}}\mathrm{K}$, and ${T}_{\mathrm{c}}\ensuremath{\approx}2.5\phantom{\rule{0.16em}{0ex}}\mathrm{K}$, corresponding to two structural and one superconducting phase transitions, respectively, demonstrating the coexistence of all of these transitions in high-quality stoichiometric samples. While there is little magnetic anisotropy, a large $ab$-plane $({\ensuremath{\rho}}_{\mathrm{ab}})$ and $c$-axis $({\ensuremath{\rho}}_{\mathrm{c}})$ electrical resistivity ratio $({\ensuremath{\rho}}_{\mathrm{c}}/{\ensuremath{\rho}}_{\mathrm{ab}}\ensuremath{\approx}730$ at $T=4\phantom{\rule{0.16em}{0ex}}\mathrm{K})$ is observed. This two-dimensional (2D) electronic character is further reflected in the disparate temperature dependences of ${\ensuremath{\rho}}_{\mathrm{ab}}$ and ${\ensuremath{\rho}}_{\mathrm{c}}$, with ${\ensuremath{\rho}}_{\mathrm{ab}}$ exhibiting a Fermi-liquid-like ${T}^{2}$ dependence below $\ensuremath{\sim}25\phantom{\rule{0.16em}{0ex}}\mathrm{K}$, while ${\ensuremath{\rho}}_{\mathrm{c}}$ deviates significantly from this standard metallic behavior. In contrast, the magnetization is almost isotropic and negative over a wide temperature range. This can be explained by larger diamagnetism induced by electronic structure reconstruction as probed by the Hall effect and smaller positive contribution from itinerant electrons due to a low density of states (DOS) at the Fermi level. A small electronic specific heat coefficient with $\ensuremath{\gamma}\ensuremath{\approx}\phantom{\rule{0.16em}{0ex}}1.8\phantom{\rule{0.16em}{0ex}}\mathrm{mJ}/\mathrm{mol}\phantom{\rule{0.16em}{0ex}}{\mathrm{K}}^{2}$ confirms this assertion. This implies that $\mathrm{IrT}{\mathrm{e}}_{2}$ is a weakly coupled superconductor. The connection between the superconductivity and the two structural transitions is discussed.
Scene-adaptive high dynamic range display for low latency augmented reality

For generalized augmented reality to be feasible, the augmenting elements must be visible in varied environments and under rapidly changing, high dynamic range lighting, from bright sunlight to deep shadows. We present a high dynamic range, optical see-through, augmented reality display that dynamically adjusts the brightness of the virtual imagery to match the current brightness of the real scene. Critical components include the spatial brightness sensor array and the positional brightness image intensity matcher. The color, scene-adaptive HDR display system is based on a high-rate (15 kHz) DMD projector using a high-speed RGB LED illuminator, each color with independent 16 bit intensity control for each binary DMD frame. The critical input to the intensity matching algorithm is the output of an array of high sensitivity light sensors. This paper discusses the implementation of the system and reports performance via still and video demonstrations under a variety of lighting conditions.
Particle Size and Chemically-Induced Variability in the Membrolytic Activity of Quartz: Preliminary Observations

Particle toxicology differs from classical chemical toxicology in that it deals exclusively with solids. The nature of the surface of a solid determines its interaction with intact animals and in vitro assays. Our rationale has been to modify the surface by reproducible techniques, such as acid, base and heat treatment, and look at the consequent differences of biological activity. Further, the dose will not be proportional to the mass of material but to the surface area, thus making particle size critical. An inorganic particulate, such as quartz, will then have a range of activities depending on the nature of its surface and its particle size (see Langer 1978 and Reiser and Last 1979). This report considers the contribution of these parameters to the membrolytic activity of quartz.
EBF2 transcriptionally regulates brown adipogenesis via the histone reader DPF3 and the BAF chromatin remodeling complex

The transcription factor early B-cell factor 2 (EBF2) is an essential mediator of brown adipocyte commitment and terminal differentiation. However, the mechanisms by which EBF2 regulates chromatin to activate brown fat-specific genes in adipocytes were unknown. ChIP-seq (chromatin immunoprecipitation [ChIP] followed by deep sequencing) analyses in brown adipose tissue showed that EBF2 binds and regulates the activity of lineage-specific enhancers. Mechanistically, EBF2 physically interacts with the chromatin remodeler BRG1 and the BAF chromatin remodeling complex in brown adipocytes. We identified the histone reader protein DPF3 as a brown fat-selective component of the BAF complex that was required for brown fat gene programming and mitochondrial function. Loss of DPF3 in brown adipocytes reduced chromatin accessibility at EBF2-bound enhancers and led to a decrease in basal and catecholamine-stimulated expression of brown fat-selective genes. Notably, Dpf3 is a direct transcriptional target of EBF2 in brown adipocytes, thereby establishing a regulatory module through which EBF2 activates and also recruits DPF3-anchored BAF complexes to chromatin. Together, these results reveal a novel mechanism by which EBF2 cooperates with a tissue-specific chromatin remodeling complex to activate brown fat identity genes.
Sentinel Lymph Node Characterization with a Dual-Targeted Molecular Ultrasound Contrast Agent.

The purpose of this study was to assess the performance of molecular ultrasound with dual-targeted microbubbles to detect metastatic disease in the sentinel lymph nodes (SLNs) in swine model of naturally occurring melanoma. The SLN is the first lymph node in the lymphatic chain draining primary tumor, and early detection of metastatic SLN involvement is critical in the appropriate management of melanoma. Nine Sinclair swine (weight 3–7 kg; Sinclair BioResources, Columbia, MO, USA) with naturally occurring melanoma were examined. Siemens S3000 scanner with a 9L4 probe was used for imaging (Siemens Healthineers, Mountain View, CA). Dual-targeted contrast agent was created using Targestar SA microbubbles (Targeson, San Diego, CA, USA) labeled with ανβ3-integrin and P-selectin antibodies. Targestar SA microbubbles labeled with IgG-labeled were used as control. First, peritumoral injection of Sonazoid contrast agent (GE Healthcare, Oslo, Norway) was performed to detect SLNs. After that, dual-targeted and IGG control Targestar SA microbubbles were injected intravenously with a 30-min interval between injections. Labeled Targestar SA microbubbles were allowed to circulate for 4 min to enable binding. After that, two sets of image clips were acquired several seconds before and after a high-power destruction sequence. The mean intensity difference pre- to post-bubble destruction within the region of interest placed over SLN was calculated as a relative measure of targeted microbubble contrast agent retention. This process was repeated for non-SLNs as controls. All lymph nodes evaluated on imaging were surgically removed and histologically examined for presence of metastatic involvement. A total of 43 lymph nodes (25 SLNs and 18 non-SLNs) were included in the analysis with 18 SLNs demonstrating metastatic involvement greater than 5 % on histology. All non-SLNs were benign. The mean intensity (± SD) of the dual-targeted microbubbles for metastatic SLNs was significantly higher than that of benign LNs (18.05 ± 19.11 vs. 3.30 ± 6.65 AU; p = 0.0008), while IgG-labeled control microbubbles demonstrated no difference in retained contrast intensity between metastatic and benign lymph nodes (0.39 ± 1.14 vs. 0.03 ± 0.24 AU; p = 0.14). The results indicate that dual-targeted microbubbles labeled with P-selectin and ανβ3-integrin antibodies may aid in detecting metastatic involvement in SLNs of melanoma.
Leaving no child with disability behind.

In Latin America and the Caribbean there are over eight million children with disabilities under the age of 14, representing one of the most excluded, discriminated and vulnerable population groups in the region. Among them, girls with disabilities and indigenous children with disabilities are subject to multiple forms of discrimination. It is estimated that seven out of ten children with disabilities do not attend school, and that at least 50 000 children and adolescents with disabilities are deprived of their family environment and live in residential institutions, representing 20% of all children living in residential care in our region.
Effects of electrical loads containing non-resistive components on electromagnetic vibration energy harvester performance

Abstract To further advance the existing knowledge base on rectified vibration energy harvester design, this study investigates the fundamental effects of electrical loads containing non-resistive components (e.g., rectifiers and capacitors) on electromagnetic energy harvester performance. Three types of electrical loads, namely (I) a resistor with a rectifier, (II) a resistor with a rectifier and a capacitor, and (III) a simple charging circuit consisting of a rectifier and a capacitor, were considered. A linear electromagnetic energy harvester was used as an illustrative example. Results have verified that device performance obtained from pure-resistive loads cannot be generalized to applications involving rectifier and/or capacitor loads. Such generalization caused not only an overestimation in the maximum power delivered to the load resistance for cases (I) and (II), but also an underestimation of the optimal load resistance and an overestimation of device natural frequency for case (II). Results obtained from case (II) also showed that it is possible to tune the mechanical natural frequency of device using an adjustable regulating capacitor. For case (III), it was found that a larger storing capacitor, with a low rectifier voltage drop, improves the performance of the electromagnetic harvester.
An approach to model error compensation in the control of nonrigid spacecraft

Summary This paper seeks to improve the convergence properties of state estimators as used in spacecraft controller designs, when the linearized model upon which the estimator is based is subject to parameter errors, truncated modes, and neglected disturbances. Instead of choosing orthogonal mode shapes multiplied by time varying coefficients (a conventional approach for modeling elastic modes) to represent the truncated modes, the “model error vector” discussed herein is approximated, over short “observation windows” τ units long, by functions which are orthogonal over the interval τ, where the coefficients of the orthogonal functions are automatically updated via the use of real time measurements from the system. The device which updates the coefficients of the orthogonal functions is called an orthogonal filter and takes on the form of a state estimator for the synthetic modes of a “model error system” which generates the orthogonal functions. The method is illustrated for a 15th order model of a flexible spacecraft, resulting in 2nd, 3rd, and 4th order controllers.
United States Postal Service Office of Inspector General

Postal oversight ensures the efficiency and integrity of postal programs, which may be accomplished with complementary postal watchdogs; however, it is best to avoid redundancies in oversight functions unless there is a compelling reason. Intended redundancies in oversight roles allow for checks and balances in the process. In countries with few oversight organizations, it is important to assure that there is adequate coverage of oversight functions. When designing comprehensive oversight programs, governments would want as many strengths contained in the oversight process as possible, exploiting the positive and mitigating the possible negative aspects of oversight. To be effective at facilitating continuous improvement via oversight, postal watchdogs need to be mindful of their role in the oversight process, demonstrate their value to the postal operator, and have mechanisms in place to improve the quality of their own programs.
Mechanical and thermo-gravimetric properties of unsaturated polyester resin blended with FGD gypsum

Abstract A major disadvantage of polymeric materials is their flammability and generation of toxic gases under fire. Mechanical and thermo-gravimetric properties of an unsaturated polyester resin blended with Flu-Gas Desulfurization (FGD) gypsum were assessed. Limited open flame tests were also performed. Results indicate that ambient mechanical properties of polyester resin can be enhanced with up to 50% FGD gypsum content. TGA results show significant improvement in mass retention proportional to gypsum content. Under direct fire, FGD gypsum can form a protective physical barrier on the resin’s exterior surfaces. FGD gypsum can potentially be an effective and low-cost fire-resistance additive for polymers.
Drug Use and HIV Prevention With Young Gay and Bisexual Men: Partnered Status Predicts Intervention Response.

The Young Men’s Health Project (YMHP) has shown efficacy in reducing drug use and condomless anal sex (CAS) with casual partners among young gay, bisexual and other men who have sex with men (YGBMSM). The study examined whether relationship status at the time of intervention predicted response to YMHP by comparing baseline (pre-intervention) and follow-up (3, 6, 9, and 12 months post-intervention) data from the original trial. A group of 13 partnered YGBMSM who received YMHP was compared to a matched subsample of single YGBMSM. Among single men, drug use declined significantly at all follow-ups. Among partnered men, drug use was largely stable. While significant reductions were observed at 9 month assessment, 3, 6, and 12 month use did not differ significantly from baseline. Regardless of relationship status, CAS with casual partners declined significantly at 12 month follow-up. Results suggest the incorporation of components which address relationship factors, particularly those associated with drug use, may enhance benefits of YMHP for partnered YGBMSM.
PSYCHOLOGICAL AND PHYSIOLOGICAL FACTORS INFLUENCING PERCEIVED EXERTION

The results from a series of experiments are presented which suggest the existence of two factors in the perception of exertion during physical work. These factors are a local factor, i.e., feelings of strain in the working muscles and/or joints, and a central factor, i.e., sensations or feelings primarily from the cardiorespiratory systems. The relative importance of these two factors are evaluated for a variety of types of physical activity such as cycling, ladder climbing (positive and negative work), treadmill walking, and stool-stepping. A model is introduced for evaluating differentiated ratings of perceived exertion (local, central and overall ratings). Utilization of this model may aid in a better psychophysiological understanding of the mechanisms by which the subjective perception of exertion is determined during different types of physical work.
A Large-Scale Experiment on the Growth and Predation Potential of Ctenophore Populations

In reviewing the ecology of planktonic ctenophores, Walter (1976) pointed out how laboratory estimations of such parameters as growth, feeding and fecundity had been utilized to interpret population dynamics of ctenophores in the natural environment. In organisms with short life-cycles, which inhabit the water column, it is usually impossible to follow the growth and mortality characteristics of cohorts by the use of such techniques as size/frequency histograms. The observer can never be sure he is sampling the same population, over a period of time, and even if this were so, continuous breeding and rapid growth tend to quickly obscure the identification of distinct cohorts. It is also not possible to experimentally manipulate the population. This report describes an experiment in which plankton populations were studied in three containers for six weeks following empoundment of a water column and its natural plankton assemblage.
Endoscopic Ultrasound and the Staging of Esophageal and Gastric Cancer

With its unique ability to provide detailed images of the gastrointestinal wall, endoscopic ultrasonography is well suited for staging of esophageal and gastric cancer. It is superior to computed tomography (CT) scanning for determination of depth of penetration of the primary tumor through the gastrointestinal wall. It is comparable to or superior to CT scanning in determining the status of regional lymph nodes. Because of its limited depth of penetration, it is less suited than CT in determining the presence or absence of distant metastases. Optimal staging information is provided by using endoscopic ultrasonography to determine T and N stage and CT scan for M stage. Endoscopic ultrasonography is a useful adjunct to established diagnostic modalities in the staging of esophageal and gastric cancer.
Selective Inhibition of Neisseria gonorrhoeae by a Dithiazoline in Mixed Infections with Lactobacillus gasseri.

The Gram-negative human pathogen Neisseria gonorrhoeae has progressively developed resistance to antibiotic monotherapies, and recent failures of dual-drug therapy have heightened concerns that strains resistant to all available antibiotics will begin circulating globally. Targeting bacterial cell wall assembly has historically been effective at treating infections with N. gonorrhoeae , but as the effectiveness of β-lactams (including cephalosporins) are challenged by increasing resistance, research has expanded into compounds that target the numerous other enzymes with roles in peptidoglycan metabolism. One example is the dithiazoline compound JNJ-853346 (DTZ), which inhibits the activity of an E. coli serine protease L,D-carboxypeptidase (LdcA). Recently, the characterization of an LdcA homolog in N. gonorrhoeae revealed localization and activity differences from the characterized E. coli LdcA, prompting us to explore the effectiveness of DTZ against N. gonorrhoeae . We found that DTZ is effective at inhibiting N. gonorrhoeae in all growth phases, unlike the specific stationary-phase inhibition seen in E. coli . Surprisingly, DTZ does not inhibit gonococcal LdcA enzyme activity, nor is DTZ sensitivity significantly decreased in ldcA mutants. While effective against numerous N. gonorrhoeae strains, including recent multi-drug resistant isolates, DTZ is much less effective at inhibiting growth of the commensal species Lactobacillus gasseri . DTZ treatment during co-infections of epithelial cells resulted in significant lowering of gonococcal burden and IL-8 secretion without significantly impacting recovery of viable L. gasseri . This selective toxicity presents a possible pathway for the use of DTZ as an effective anti-gonococcal agent at concentrations that do not impact vaginal commensals.
Nonlinear modeling of concentrically braced frames

Abstract Concentrically braced frames (CBFs) comprise a large proportion of lateral-force-resisting systems used in steel building infrastructure around the world. Many categories of CBFs exist, including special, ordinary, and non-seismically detailed (i.e., current “R = 3” or pre-1988 construction) CBFs. Experimental testing of these different types of CBFs has shown that they have widely varying nonlinear behavior depending on the relative strengths of their yielding mechanisms and failure modes and level of ductile detailing. Numerical modeling of this range of behavior types is necessary to evaluate the seismic performance, including to quantify potential damage to special CBFs and the vulnerability of lower-ductility CBFs. Special CBFs have been the focus of many previous nonlinear modeling recommendations, including simulation of brace fracture, gusset-plate flexural strength and stiffness, and gusset-plate contribution to frame stiffness. However, recommendations for lower-ductility CBFs have not been well established. To provide important guidance for modeling these common systems, new recommendations based on the large quantity of available experimental data are proposed for simulating fracture of rectangular HSS braces with varying local slenderness, asymmetric load histories, and concrete in-fill; axial yielding of gusset plates; fracture of brace-to-gusset-plate welds; fracture of gusset-plate interface welds; post-fracture, secondary yielding mechanisms in gusset-plate interface connections; yielding beams in the chevron configuration; and buckling columns. These recommendations are validated using experiments of two-story chevron CBFs with yielding beams which simulated an existing, pre-1988 CBF (i.e., a nonductile CBF) and a subsequent repair where the braces and gusset plates were replaced.
“We're building the community; it's a hub for democracy.”: Lessons learned from a library-based, school-district partnership and program to increase belonging for newcomer immigrant and refugee youth

Abstract This community-based mixed-methods evaluation study investigates how a library-based program increases belonging for newcomer youth. This article presents the qualitative analysis from a mixed-methods study in progress. The article describes the library's community practice of advocating for newcomers with meaningful programming that increases understanding of community resources, local politics, and belonging. Key findings relate to the project leaders' perceptions of the library as a hub for democracy, how the program positively increased belonging for newcomers, and challenges and lessons learned from the first year of the program. Implications for practice demonstrate how the asset-based program through the library-school district partnership counteracts hostile political climates toward newcomers.
Vascular Access: Ostomies and Drains Care in Palliative Medicine

Palliative care focuses upon supporting the patient’s directed goals of care. Safety and relief of symptoms are important even if alternative measures are put into place. Palliative care manages the imminent dying patient, advanced disease, and catastrophic injury as well as the early stages of a curable disease. The bereavement period after the patient’s death is an extension of palliative care for the family.
Session Types with Arithmetic Refinements and Their Application to Work Analysis.

Session types statically prescribe bidirectional communication protocols for message-passing processes and are in a Curry-Howard correspondence with linear logic propositions. However, simple session types cannot specify properties beyond the type of exchanged messages. In this paper we extend the type system by using index refinements from linear arithmetic capturing intrinsic attributes of data structures and algorithms so that we can express and verify amortized cost of programs using ergometric types. We show that, despite the decidability of Presburger arithmetic, type equality and therefore also type checking are now undecidable, which stands in contrast to analogous dependent refinement type systems from functional languages. We also present a practical incomplete algorithm for type equality and an algorithm for type checking which is complete relative to an oracle for type equality. Process expressions in this explicit language are rather verbose, so we also introduce an implicit form and a sound and complete algorithm for reconstructing explicit programs, borrowing ideas from the proof-theoretic technique of focusing. We conclude by illustrating our systems and algorithms with a variety of examples that have been verified in our implementation.
Isolation of an HLA-A:,B:,C Null Human Cell Line Capable of Expressing Transferred Class I Genes

The functional and molecular analysis of the human leukocyte antigen (HLA) complex has benefited from the generation of γ-ray-induced mutant cells that have lost expression of various HLA gene products. The technique of γ-ray mutagenesis and negative immunoselection (1) has been used to isolate a human B-lympho blastoid cell line (B-LCL) that does not express the serologically defined HLA-A,B,C class I antigens but can serve as a recipient cell for cloned HLA class I genes introduced by DNA-mediated gene transfer. This HLA-A,B,C null human cell has enabled us to produce B-LCL transferents that express only one HLA-A, -B, or -C antigen—that encoded by a transferred class I gene.
Magnetoresistance effects in cadmium arsenide thin films

In-plane magnetoresistance effects in the three-dimensional Dirac semimetal cadmium arsenide are studied as a function of film growth orientation, film thickness, and surface Fermi level. For films with the Fermi level near the bulk nodes, which are gapped for very thin films, a pronounced planar Hall effect is observed due to the combination of magnetoresistance effects from the Berry phase and orbital magnetoresistance. At high Fermi levels, surface state transport produces weaker magnetoresistance effects. The results are discussed in the context of detecting signatures of the chiral anomaly.
Solubility, solvent effect, molecular simulation and thermodynamic properties of clozapine in twelve pure solvents

Abstract In this article, laser monitoring technology was used to study the solubility of clozapine in 2-methoxyethanol, 2-ethoxyethanol, 2-propoxyethanol, ethanol, n-propanol, n-butanol, n-pentanol, methyl acetate, ethyl acetate, n-propyl acetate, n-butyl acetate, n-pentyl acetate under the pressure of 0.1 MPa (at 278.15 K–323.15 K). Obviously, the mole fraction solubility of clozapine is positively correlated with the increase of experimental temperature. KAT-LSER model was used to study the solvent effect of clozapine solubility in 12 pure solvents. The results show that the interaction of solvent–solute is mainly due to the dipolarity/polarizability and solvent’s self-cohesiveness. The interaction between solute–solvent molecules was analysed by MD simulation, and the results show that the interaction between solute–solvent molecules has an important influence on the solubility of clozapine. Then the solubility data of clozapine were put into five classical thermodynamic models for simulation, namely the λh model, Apleblat model, NRTL model, Margules model and UNIQUAC model. The values calculated by the five solubility models are in good agreement with the measured solubility, it means that the five models have a higher level of simulation accuracy. On the other hand, the apparent thermodynamic properties of clozapine dissolved in solvent were calculated by van’t Hoff equation, the results show that the dissolution process of clozapine in solvents is an endothermic and driven by enthalpy.
A conversation with Iván Chaar López

Being watched means much more than being seen. This forum investigates information flows of sensing culled from sources as diverse as temperature check and iris scans to sound and movement sensors across terrains. After Veillance discusses how these systems distribute risk unevenly and shape the lives of populations across the globe. --- Sareeta Amrute, Editor
Scavenging for evidence: A systematic review of scavenger hunts in academic libraries

Abstract Introduction Scavenger Hunts have longstanding popularity as an outreach and instruction learning tool in academic libraries. This systematic review examines the implementation and assessment of scavenger hunts in academic library settings to determine trends in implementation and effectiveness. Methods A systematic literature search in multiple databases was performed to identify studies that assessed academic library scavenger hunts. Results that did not include some physical aspect of a scavenger hunt in a library building, and results that lacked some form of assessment of the scavenger hunt were excluded. Results Thirteen case studies utilizing various forms of formal and informal assessment were included. Only four articles explicitly stated the population involved in the assessment, and one article provided a decisive timeframe for the scavenger hunt. The most commonly stated desired outcome was for students to have fun and/or be engaged. Assessment tools reported in the included articles were rarely reviewed or tested for validity. Discussion The available literature on scavenger hunts in academic libraries does not provide enough evidence to make an evidence-based decision on utilizing this modality. Recording participant demographic data, and focus on assessing the scavenger hunt as an effective tool are suggestions for improving future library-based scavenger hunts.
Loss of C2 Domain Protein (C2CD5) Alters Hypothalamic Mitochondrial Trafficking, Structure, and Function.

Introduction Mitochondria are essential organelles required for several cellular processes ranging from ATP production to cell maintenance. To provide energy, mitochondria are transported to specific cellular areas in need. Mitochondria also need to be recycled. These mechanisms rely heavily on trafficking events. While mechanisms are still unclear, hypothalamic mitochondria are linked to obesity. Methods We used C2 domain protein 5 (C2CD5, also called C2 domain-containing phosphoprotein [CDP138]) whole-body KO mice primary neuronal cultures and cell lines to perform electron microscopy, live cellular imaging, and oxygen consumption assay to better characterize mitochondrial alteration linked to C2CD5. Results This study identified that C2CD5 is necessary for proper mitochondrial trafficking, structure, and function in the hypothalamic neurons. We previously reported that mice lacking C2CD5 were obese and displayed reduced functional G-coupled receptor, melanocortin receptor 4 (MC4R) at the surface of hypothalamic neurons. Our data suggest that in neurons, normal MC4R endocytosis/trafficking necessities functional mitochondria. Discussion Our data show that C2CD5 is a new protein necessary for normal mitochondrial function in the hypothalamus. Its loss alters mitochondrial ultrastructure, localization, and activity within the hypothalamic neurons. C2CD5 may represent a new protein linking hypothalamic dysfunction, mitochondria, and obesity.
Design of a Depth Control Mechanism for an Anguilliform Swimming Robot

This paper discusses the design and implementation of a depth control mechanism for an anguilliform swimming robot. Researchers analyzed three different methods of controlling the depth of the robot, including out-of-plane thrust direction, use of foil on the head and buoyancy control at the head and tail. It was determined that buoyancy control at the head and tail was the best method for controlling depth and pitch, given typical forward speeds of the robot. Details are given into the design of this mechanism, including a stress analysis on a critical part, as well as the impacts that these modifications have on the required torque of the drive servos.
Quinidine in the Management of Recurrent Ventricular Arrhythmias: A Reappraisal

OBJECTIVE: We aimed to study quinidine's utility in patients presenting with recurrent sustained VA and limited AAD options. \ BACKGROUND: Antiarrhythmic drug (AAD) options are often limited in patients with structural heart disease and recurrent ventricular arrhythmias (VA). Quinidine has an established role in rare arrhythmic syndromes, but its potential use in other difficult VA has not been assessed in the present era. METHODS: We performed a retrospective analysis of 37 patients who had in-hospital quinidine initiation after multiple other therapies failed for VA suppression at our tertiary referral center. Clinical data and outcomes were obtained from the medical record. RESULTS: Of 30 patients with in-hospital quantifiable VA episodes, quinidine reduced acute VA from a median of 3 episodes (interquartile range [IQR] 2 - 7.5) to 0 (IQR 0 - 0.5), during a median of 3 days before, and 4 days after quinidine initiation (P < 0.001). VA events decreased from a median of 10.5 episodes (IQR 5-15) to 0.5 episodes (IQR 0-4) after quinidine initiation in the 12 patients presenting with electrical storm (P = 0.004). Among the 24 patients discharged on quinidine, 13 patients (54.2%) had VA recurrence during a median of 138 days. Adverse effects in 9 of the 37 (24.3%) patients led to drug discontinuation, most commonly gastrointestinal (GI) intolerance. CONCLUSION: In patients with recurrent VA and structural heart disease who have limited treatment options, quinidine can be useful, particularly as a short-term therapy.
Analysis of 16 Coils Over 50 MRI-Derived Head Models in Transcranial Magnetic Stimulation

Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation technique investigated for the treatment of various neuropsychiatric disorders such as major depressive disorder and obsessive-compulsive disorder. Coil design and analysis has been a popular topic in TMS studies, primarily as the coil geometry significantly affects the induced electric field ( $E$ -field) distribution. In this work, we compare the distribution of the induced $E$ -field of 16 different TMS coils by finite element analysis. The coils are positioned at two head locations: the vertex and the dorsolateral prefrontal cortex (DLPFC). Due to the coil geometry, only nine of the 16 coils are positioned at the DLPFC. Notably, the authors use 50 heterogeneous head models derived from MRI scans of healthy patients in this analysis. As a result, the sensitivity of the $E$ -field intensity and focality to anatomical variations is investigated. The maximum $E$ -field intensity induced in the brain ( $E$ -Max brain), and the volume in the brain exposed to the $E$ -field with at least half the $E$ -Max ( $V$ -Half) were metrics used to assess the intensity and focality of the induced $E$ -field. It was observed that some of the coils induced high $E$ -field intensity and were highly sensitive to anatomical variations. Other coils exhibited high focality and lower sensitivity to anatomical variations at the same time. For the coils positioned at the DLPFC, less variability was observed when compared to the vertex location. This study provides an understanding of the effect of coil geometry and anatomical variation on the induced $E$ -field during TMS.
A semi-supervised active learning algorithm for information extraction from textual data: Research Articles

In this article we present a semi-supervised active learning algorithm for pattern discovery in information extraction from textual data. The patterns are reduced regular expressions composed of various characteristics of features useful in information extraction. Our major contribution is a semi-supervised learning algorithm that extracts information from a set of examples labeled as relevant or irrelevant to a given attribute. The approach is semi-supervised because it does not require precise labeling of the exact location of features in the training data. This significantly reduces the effort needed to develop a training set. An active learning algorithm is used to assist the semi-supervised learning algorithm to further reduce the training set development effort. The active learning algorithm is seeded with a single positive example of a given attribute. The context of the seed is used to automatically identify candidates for additional positive examples of the given attribute. Candidate examples are manually pruned during the active learning phase, and our semi-supervised learning algorithm automatically discovers reduced regular expressions for each attribute. We have successfully applied this learning technique in the extraction of textual features from police incident reports, university crime reports, and patents. The performance of our algorithm compares favorably with competitive extraction systems being used in criminal justice information systems. © 2005 Wiley Periodicals, Inc.
The Dawn of the Modern Age

Leonhard Euler (1707–1783)was one of the greatest mathematicians who ever lived. Hewas also one of the most prolific. His collected works comprise more than 70 volumes, and they are still being edited today. Euler worked in all parts of mathematics, as well as mechanics, physics, and many other parts of science. He did mathematics almost effortlessly, often while dangling a grandchild on his knee. Late in life he became partially blind, but he declared that this would help him to concentrate more effectively, and his scientific output actually increased.
Magnetic ground state of semiconducting transition-metal trichalcogenide monolayers

Layered transition-metal trichalcogenides with the chemical formula $AB{X}_{3}$ have attracted recent interest as potential candidates for two-dimensional magnets. Using first-principles calculations within density functional theory, we investigate the magnetic ground states of monolayers of Mn- and Cr-based semiconducting trichalcogenides. We show that the second and third nearest-neighbor exchange interactions (${J}_{2}$ and ${J}_{3}$) between magnetic ions, which have been largely overlooked in previous theoretical studies, are crucial in determining the magnetic ground state. Specifically, we find that monolayer ${\mathrm{CrSiTe}}_{3}$ is an antiferromagnet with a zigzag spin texture due to significant contribution from ${J}_{3}$, whereas ${\mathrm{CrGeTe}}_{3}$ is a ferromagnet with a Curie temperature of 106 K. Monolayers of Mn compounds (${\mathrm{MnPS}}_{3}$ and ${\mathrm{MnPSe}}_{3}$) always show antiferromagnetic N\'eel order. We identify the physical origin of various exchange interactions, and demonstrate that strain can be an effective knob for tuning the magnetic properties. Possible magnetic ordering in the bulk is also discussed. Our study suggests that $AB{X}_{3}$ can be a promising platform to explore two-dimensional magnetic phenomena.
Numerical simulation of ventilation in blinding heading

The way of ventilation in all its forms and characteristics in the blinding heading was studied. On the basis of computational fluid dynamics (CFD) the turbulence model of restrained ventilation in blinding heading was set up, and the calculation boundary conditions were analyzed. According to the practice application the three-dimensional flow field of ventilation in blinding heading was simulated by the computational fluid dynamics software. The characteristics of the ventilation flow field such as the temperature field zone and the flow filed zone and the rule of the flow velocity were obtained. The ventilation in blinding heading under certain circumstances was calculated and simulated for optimization. The optimal ventilation form and related parameters under given condition were obtained. The rule of the ventilation in blinding heading was theoretical analyzed, which provided reference for the research on the process of mass transfer, the rule of hazardous substances transportation and ventilation efficiency, provided a new method for the study of reasonable and effective ventilation in blinding heading.
Low temperature copper de-oxidation

The impact of a post deposition annealing step of ECD copper and of a predeposition annealing step on the Cu seed has been investigated. Compared to forming gas it can be demonstrated that the addition of a small amount of ethanol can very effectively reduce the surface and grain boundary oxidation with benefits for the electrical parameters. The impact of a de-oxidation step down to 100degC on the Cu seed and its consequences for the ECD Cu growth are presented