cssi/SciSciGPT-SciSciNet huggingface dataset:
Topographies of Disruption: Queer(ed) Literacy Pedagogies Beyond the Binary

This article seeks to imagine the ways in which queer theor(ies), particularly those related to space and discourse, might hold implications for the (re)structuring of formal educational spaces. Through narrativizing the experiences of queer students, teachers, and moments in school, I hope to develop an understanding of what we might call “queer pedagogy/-ies,” wherein moments of disruption can be mined to cultivate more humane, soulful, and equitable school cultures. In leaning particularly on the work of feminist and queer theorist Sara Ahmed, I study how phenomena like “straightening devices” and “grid lines” act as regulating forces to maintain the status quo in schools, eclipsing opportunities for a queer imaginary and creative logic to rupture forth. In recalling how students often practice literacies of resistance, I outline how teachers might begin to (re)imagine pedagogy as being queered: as being intersectional, future-oriented, embodied, expansive, and, paradoxically, silent.
Pathogenic analysis of the first case of human granulocytic anaplasmosis in Zhejiang Province

Objective To take etiological diagnosis and molecular biological analysis for the first case of human granulocytic anaplasmosis in Zhejiang Province.Methods A.phagocytophilum 16S rRNA was detected and sequenced by molecular biological metyods.Serum A.phagocytophilum IgG antibody in clinical stage and 3 months after recovery were detected by indirect immonufluorescence technique.Results The PCR products of the expected size,282 bp and 389 bp were obtain in blood from the patient at pyrogenic stage.The 389 bp nucleotide sequence was compared with A.phagocytophilum 16S rRNA nucleotides previously published in GenBank.The homology was 99.73％.Serum IgG antibody to A.phagocytophilum was positive in 1:128 titer at pyrogenic stage and had 4-fold decline after convalescence.Conclusions The first case of human granulocytic anaplasmosis is confirmed in Zhejiang Province.There is no obvious differece between 16S rRNA from the patient and A.phagocytophilum known before. Key words: Anaplasma phagocytophilum; Etiological diagnosis; PCR; Indirect immunofluorescence assay
The correlation of circulating miR-29b and inflammatory markers with albuminuria in hypertensive patients.

Circulating miR-29b and inflammatory process play a vital role in hypertension and hypertensive nephropathy. The aim of the present study was to investigate the association of circulating miR-29b a...
Suppressed quadriceps fascicle behavior is present in the surgical limbs of those with a history of ACL reconstruction

Abstract The balance of published data have largely focused on adaptations in muscle and fiber size after anterior cruciate ligament reconstruction (ACLR), failing to account for the dynamic changes in the behavior of the muscles’ contractile elements that strongly contribute to force production. To better understand the sources of quadriceps dysfunction, the purpose of our research was to determine if alterations in fascicle behavior are present after ACLR. Unilateral ACLR individuals (9 m/9f; 21 ± 3 yrs; 1.74 ± 0.12 m;71.58 ± 13.31 kg; months from surgery:38 ± 36) and healthy controls (3 m/6f; 23 ± 2 yrs; 1.67 ± 0.10 m; 63.51 ± 10.11 kg) participated. In-vivo vastus lateralis fascicle behavior was recorded using ultrasonography during three maximal isokinetic knee extensions (60°·s−1). Fascicle length, angle, and shortening velocity were calculated and analyzed from rest to peak torque. Peak knee extension torque was averaged between isokinetic trials (Nm·kg−1). Group by limb interactions were assessed using separate two-way analyses of variance and were further evaluated by comparing 95% confidence intervals where appropriate. Significant interactions were present for fascicle angle at peak torque (P = 0.01), fascicle length excursion (P = 0.05), fascicle angle excursion (P 0.05). Our data show that those with a history of ACLR have fascicles that are slower, lengthen less and operate with lower angles relative to the axis of force production. Altered fascicle behavior after ACLR may be an important underlying factor to explaining the protracted quadriceps dysfunction.
Basal Area Growth Estimators for Survivor Component: A Quality Control Application

Several possible estimators are available for basal area growth of survivor trees, when horizontal prism (or point) plots (HPP) are remeasured. This study’s comparison of three estimators not only provides a check f o r the estimate of basal area growth but suggests that they can provide a quality control indicator for yield procedures. An example is derived from remeasurements in Alabama for the Southern Forest E x p e r i m e n t Station by Forest Inventory and Analysis. Remeasurements are for 1962-72 and 1972-82. It is suggested that computation of two or perhaps all three of the estimators be routinely incorporated in analysis of remeasured HPP d a t a . U s e of the two elemental estimators can provide a quality assurance check on f ie ld procedures.
Retinal protein synthesis in relationship to environmental lighting.

A series of in vivo and in vitro experiments using Xenopus laevis juvenile toads was conducted to probe the relationship between environmental lighting and protein synthesis in the retina. Autoradiographic and biochemical analyses indicated that measurable changes in protein synthesis did not occur during a normal diurnal cycle when animals were conditioned to 12 hr light followed by 12 hr darkness each day (LD). However, when retinas from animals maintained in continuous darkness (DD) for 3 days were incubated with /sup 3/H-leucine, there was a 40% reduction in the specific radioactivity of total retinal proteins compared with retinas from animals maintained in continuous light (LL) for 3 days or on the LD cycle. Retinas from DD animals injected with /sup 3/H-leucine showed a 48% reduction in protein synthesis compared with retinas of LL animals. In autoradiographs of retinas from in vivo or in vitro experiments, grain counts were 40% lower in the total retinas of the DD animals compared with retinas of LL animals. This reduction occurred throughout the entire retina and was not restricted to any specific cell type. There was also a 35% reduction in the rate of radioactive band displacement in the rod outer segments of DDmore » animals, although the percent of /sup 3/H-leucine incorporated into opsin relative to total retinal protein was the same for both groups. We conclude from these studies that fluctuations in the rate of protein synthesis during the normal light-dark cycle are not detectable. However, major differences in protein synthesis are evident when animals are stressed with continuous darkness for several days. This effect is not restricted to any particular retinal layer but occurs throughout the entire retina. Moreover, prolonged darkness affects protein synthesis in extraocular tissues as well.« less
Inspiratory bursts in the preBötzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice.

Inspiratory neurons of the preBotzinger complex (preBotC) form local excitatory networks and display 10–30 mV transient depolarizations, dubbed inspiratory drive potentials, with superimposed spiking. AMPA receptors are critical for rhythmogenesis under normal conditions in vitro but whether other postsynaptic mechanisms contribute to drive potential generation remains unknown. We examined synaptic and intrinsic membrane properties that generate inspiratory drive potentials in preBotC neurons using neonatal mouse medullary slice preparations that generate respiratory rhythm. We found that NMDA receptors, group I metabotropic glutamate receptors (mGluRs), but not group II mGluRs, contributed to inspiratory drive potentials. Subtype 1 of the group I mGluR family (mGluR1) probably regulates a K+ channel, whereas mGluR5 operates via an inositol 1,4,5-trisphosphate (IP3) receptor-dependent mechanism to augment drive potential generation. We tested for and verified the presence of a Ca2+-activated non-specific cation current (ICAN) in preBotC neurons. We also found that high concentrations of intracellular BAPTA, a high-affinity Ca2+ chelator, and the ICAN antagonist flufenamic acid (FFA) decreased the magnitude of drive potentials. We conclude that ICAN underlies robust inspiratory drive potentials in preBotC neurons, and is only fully evoked by ionotropic and metabotropic glutamatergic synaptic inputs, i.e. by network activity.
Aspects of Optimality in the Eigenvalue Assignment Problem

The eigenvalue assignment problem involves finding a state feedback vector k such that the eigenvalues of A-bkT are in the desired locations. This paper considers the case where the system is not completely controllable, and the solution for the feedback gain vector k is not unique. The set of possible solutions for the feedback gain vector is identified, and optimal solutions are defined in the sense of minimum 2-norm, minimum infinite-norm (minimum maximum gain), and maximum number of zero gain elements in k. In addition, the methods presented here can also be applied to the case where linear state-variable feedback is applied to more than one input.
The design and evaluation of the neutral posture chair for surgeons.

A neutral posture chair was designed and evaluated to determine if it was a possible means for reducing or eliminating fatigue experienced by surgeons because of seated body posture during microsur...
μ-­opioid Receptor: Opioid Painkillers Redefined

According to the CDC, common opioid painkillers kill twice as many people as cocaine and five times as many as heroin. They cause addiction, detrimental side effects, and become less effective over...
Influence of Elevated Circulating Levels of Amino Acids on Cerebral Concentrations and Utilization of Amino Acids

Publisher Summary The relationship between circulating and tissue levels of various amino acids does not follow any consistent pattern partly as a consequence of: competitive interactions in membrane transport, variations in intracellular metabolism, and differential effects of other regulatory factors. If the restriction is great, parenteral administration of large quantities of an amino acid results in elevated concentrations of this substance in cerebral tissues. Under these circumstances, cerebral concentrations of certain other amino acids may be acutely depressed. Data in the literature suggests that two principal mechanisms might be responsible for competition among amino acids for brain transport systems. The investigations summarized in this report provide evidence that both of these processes were responsible for the acute lowering of cerebral levels of several amino acids in the presence of elevated circulating concentrations of another amino acid. Methods for carrying out the experiments are described in this chapter. The chapter discusses about the dependence of normal brain activity and mental performance on the proper functioning of amino acid metabolism.
FET THZ DETECTORS OPERATING IN THE QUANTUM CAPACITANCE LIMITED REGION

In this paper, we report our studies on field effect transistor (FET) THz detectors operating in the non-resonant mode based on the Dyakonov-Shur plasma wave detection theory, where the quantum capacitance dominates. The influence of quantum capacitance in detector response is theoretically developed and numerically simulated at low and high frequencies. Fundamental constraints in the upper frequency limit are also analyzed for FET THz detectors based on various materials, showing advantages of GaN for 8 - 20 THz applications. Experiments at microwave and THz frequencies have been carried out for GaN based devices showing agreement with the theory.
Methamphetamine effects on blood-brain barrier structure and function.

Methamphetamine (Meth) is a widely abuse psychostimulant. Traditionally, studies have focused on the neurotoxic effects of Meth on monoaminergic neurotransmitter terminals. Recently, both in vitro and in vivo studies have investigated the effects of Meth on the BBB and found that Meth produces a decrease in BBB structural proteins and an increase in BBB permeability to various molecules. Moreover, preclinical studies are validated by clinical studies in which human Meth users have increased concentrations of toxins in the brain. Therefore, this review will focus on the structural and functional disruption of the BBB caused by Meth and the mechanisms that contribute to Meth-induced BBB disruption. The review will reveal that the mechanisms by which Meth damages dopamine and serotonin terminals are similar to the mechanisms by which the blood-brain barrier (BBB) is damaged. Furthermore, this review will cover the factors that are known to potentiate the effects of Meth on the BBB, such as stress and HIV, both of which are co-morbid conditions associated with Meth abuse. Overall, the goal of this review is to demonstrate that the scope of damage produced by Meth goes beyond damage to monoaminergic neurotransmitter systems to include BBB disruption as well as provide a rationale for investigating therapeutics to treat Meth-induced BBB disruption. Since a breach of the BBB can have a multitude of consequences, therapies directed towards the treatment of BBB disruption may help to ameliorate the long-term neurodegeneration and cognitive deficits produced by Meth and possibly even Meth addiction.
Swarm-Based Knowledge Discovery for Intrusion Behavior Discovering

In this research, we developed a technique, the Swarm-based Visual Data Mining approach (SVDM), that will help user to gain insight into the Intrusion Detection System (IDS) alert event data stream, come up with new hypothesis, and verify the hypothesis via the interaction between the human and the system. This novel malicious user detection system can efficiently help security officer detect anomaly behaviors of malicious user in the high dimensional time dependent state spaces. This system's visual representations exploit the human being's innate ability to recognize patterns and utilize this ability to help security manager understand the relationships between seemingly discrete security breaches.
Inquiry-based laboratory activity to investigate physical growth requirements of microorganisms.

Standard "cookbook" laboratory activities that are used to teach students the optimal physical growth conditions of microorganisms should be modified so that they more effectively foster student's higher order cognitive skills and attract student interest. This paper describes a laboratory activity that engages students in an inquiry-based approach to studying the physical growth requirements of microorganisms. In this activity, students design and implement an experiment to obtain pure cultures of specific microorganisms, with distinct growth properties, that are provided to them in a mixed culture.
Granulocytic Sarcoma Potential Diagnostic Clues From Immunostaining Patterns Seen With Anti-Lymphoid Antibodies

Because of shared histologic and clinical features, granulocytic sarcoma (GS) may be confused with B- and T cell malignant lymphomas. Antibodies to myeloperoxidase, lysozyme, CD 15, and other deter...
A New Approach to Streambed Modeling and Simulation Using CFD

Realistic three-dimensional computer models of natural streams and rivers have become a priority for many civil works researchers, particularly in light of the exorbitant costs associated with typical stream restoration. Fortunately, the rapid advances and availability of high performance computing resources along with the increased sophistication of both in-house and commercial software have made the creation of such models significantly more tenable. In light of these needs, the objectives for this research include: (1) the creation of realistic representations of naturally occurring streambeds from potentially coarse sets of field measurements; (2) the demonstrated capability to freely deform the streambed surface as well as embed complex objects within the surface (rocks, fallen trees, etc.); (3) the ability to successfully mesh the surface and its surrounding volume in accordance with established mesh quality criteria; and (4) the ability to obtain sufficiently resolved flow field solutions utilizing HPC resources. Beginning with a coarse set of field data measurements taken from one of four study sites along a 1.5-mile stretch along the Robinson restoration project of the Merced River, California, we will demonstrate, for each objective stated, the respective challenges, solution strategies, and resulting outcomes. Flow field solutions are conducted using parallelized finite element/volume solvers.
Temporal and spatial characteristics of Pc1 waves observed by ST5

[1] We present the results of a study of Pc1 waves (0.2–5 Hz) recorded by the three spacecraft of NASA's Space Technology 5 (ST5) mission, which operated in a dawn-dusk, 300 × 4500 km Sun-synchronous orbit in a “string-of-pearls” configuration from 26 March through 23 June 2006. Regions with Pc1 wave activity are not only localized to rather narrow L shells but can appear and disappear on the time scales of ∼10 s to 10 min as examined by ST5. Only half of the 48 identified events were observed by all three spacecraft, and five events were observed by only one spacecraft. Only seven events were observed below L = 4, and only one was observed below L = 3.6, consistent with the relatively quiet geomagnetic conditions during this interval. The temporal occurrence distribution of Pc1 events was similar to that recorded at Halley, Antarctica (L = 4.56), during this same interval in that the number and intensity of events increased during magnetospheric compressions and during the recovery phase of magnetic storms, but they were reduced or absent during main phase and early recovery phase. This agreement suggests that if Pc1 events occur during main phase, their nearly universal absence in ground records cannot be ascribed to ionospheric screening effects or obscuration by irregular ULF noise generated in the ionosphere. These findings also suggest that although electromagnetic ion cyclotron waves might theoretically cause rapid depletion of radiation belt electrons during the main phase of storms, such waves cannot be assumed to occur during the main phase of all storms.
Parathyroid surgery in pregnancy: review of the literature and localization by aspiration for parathyroid hormone levels

To review the management of primary hyperparathyroidism in pregnant women by focusing on the use of preoperative localization procedures and minimally invasive parathyroid surgery during pregnancy. We report the clinical course of two pregnant women with severe hypercalcemia due to primary hyperparathyroidism, as well as review the literature. Primary hyperparathyroidism in pregnant women is associated with high prevalence of maternal and neonatal complications. In women, with severe hypercalcemia, parathyroid surgery during pregnancy reduces fetal and maternal morbidities. Preoperative localization of parathyroid adenomas during pregnancy remains challenging. In selected cases aspiration of nodules suspected of being parathyroid adenomas with the measurement of the parathyroid hormone (PTH) from the aspirate can localize the adenoma, and allow the surgeon to carry out a minimally invasive parathyroidectomy. Localization of a suspected parathyroid adenoma by ultrasound-guided aspiration of a lesion and the measurement of the PTH has previously been described in non-pregnant women. Our review of the literature did not identify any previous case of a pregnant woman with primary hyperparathyroidism, where preoperative localization of a parathyroid adenoma was accomplished by aspiration of a suspected lesion followed by a successful minimally invasive parathyroidectomy carried out during pregnancy.
Shattered lives and broken childhoods: Evidence of physical child abuse in ancient Egypt

Abstract Much can be learned about cultural attitudes of violence towards children from the analyses of their skeletal remains and mortuary patterns of the communities in which they lived and died. A bioarchaeological approach integrating biological, socio-cultural, and physical environments is used in analyzing the remains of a 2–3-year-old child from Kellis 2, a Romano-Christian period cemetery in the Dakhleh Oasis, Egypt. The skeletal remains of this individual show an unusual pattern of trauma and healing events, possibly indicating multiple episodes of non-accidental trauma. Macroscopic, radiographic, and histologic analyses show the extent of the skeletal trauma and healing, while stable carbon and nitrogen analyses of bone and hair reveal metabolic disturbances and changes in diet correlated with these traumatic events. Results from the differential diagnosis demonstrate that this individual exhibits skeletal fracture and healing patterns consistent with repeated non-accidental trauma, which may or may not have resulted in death. In addition, this individual may also represent the earliest documented case of violence against children from an archaeological context.
Isolation and identification of 5-methylthioribose from Escherichia coli B.

Abstract 5-Methylthioribose was isolated after incubation of Escherichia coli B in a glucose-salts medium. At least 60% of the radioactivity in absolute ethanol extracts of the residue from lyophilized medium supplemented with 35 SO 4 2− was located in two chromatographic areas that were identified as 5-methylthioribose and its sulfoxide. The sulfoxide was formed by oxidation of 5-methylthioribose during necessary processing of cultures and fractions. These compounds were characterized by functional group analysis and chromatographic comparison with authentic material. 5-Methylthioribose sulfoxide was isolated from 12 l of incubation medium of E. coli . After purification in three paper and one thin-layer chromatographic systems, 50 μg was obtained. The trimethylsilyl derivative of this compound was compared with that of authentic 5-methylthioribose sulfoxide. Gas chromatography and mass spectrometry confirmed the identity. This is the first report of 5-methylthioribose from a bacterium.
UDP-galactose-glycoprotein galactosyltransferase from canine tracheal mucosa.

Abstract UDPgalactose-glycoprotein galactosyltransferase from canine tracheal mucosa was studied using desialized bovine submaxillary mucin as acceptor. A lipid intermediate is not involved in the reaction.
An ICT-Based Approach to Ratiometric Fluorescence Imaging of Hydrogen Peroxide Produced in Living Cells

We present the synthesis, properties, and biological applications of Peroxy Lucifer 1 (PL1), a new fluorescent probe for imaging hydrogen peroxide produced in living cells by a ratiometric response. PL1 utilizes a chemoselective boronate-based switch to detect hydrogen peroxide by modulation of internal charge transfer (ICT) within a 1,8-naphthalimide dye. PL1 features high selectivity for hydrogen peroxide over similar reactive oxygen species, including superoxide, and nitric oxide, and a 65 nm shift in emission from blue-colored fluorescence to green-colored fluorescence upon reaction with peroxide. Two-photon confocal microscopy experiments in live macrophages show that PL1 can ratiometrically visualize localized hydrogen peroxide bursts generated in living cells at immune response levels.
The Estimation of Induced-Voltage Peak Magnitude and Energy Level Under LTA/EMP Excitation of Low-Loss Aircraft Cabling

The important vulnerability parameters of peak voltage transient magnitude and voltage transient energy are estimated for the LTA/EMP induction problem. Using basic linear system theory, straightforward expressions are derived to estimate these two survivability parameters. The derived model is quite general including cable characteristics, varying terminating impedances , and varying points of cable excitation. Using the developed model, a comparison of the LTA and EMP cases is made. An iliustrative example involving the yaw-damper circuit of the USAF f-l11 is also included.
The interaction of hydrogen and cyclopropane with the (110) surface of iridium

The interaction of cyclopropane with hydrogen and the residue resulting from the decomposition of the former on the reconstructed Ir(110)-(1×2) surface has been studied with thermal desorption mass spectrometry. Although hydrogen will not adsorb onto the saturated overlayer of dissociatively adsorbed cyclopropane, the preadsorption of hydrogen into the β2 adstate inhibits the decomposition of cyclopropane on the surface. Desorption of the hydrogen from the saturated overlayer of the dissociatively adsorbed cyclopropane partially regenerates the reactivity of the surface.
DETERMINATION OF WATER IN NINETEEN USGS GEOCHEMICAL REFERENCE STANDARDS USING COULOMETRY AND NEUTRON‐CAPTURE PROMPT GAMMA‐RAY SPECTROSCOPY

Nineteen USGS GRSs were analyzed with a Dupont 903-H Moisture Analyzer at 110°C and 1000°C to obtain H2O-and H2O+, and by thermal neutron induced gamma-ray spectrometry to obtain total H2O. The values are compared with the current literature and the two techniques evaluated. Except for QLO-1 by coulometry, no significant differences were obtained when the results were compared to the the literature.
Psychological Contours of Multicultural Feminist Hermeneutics: Han and Relationality

The two key psychological contours, han and relationality, in interpreting and understanding biblical texts among Korean/Asian North American women are discussed. The Old Testament biblical narrative of Jephthah’s daughter (Judges 11) is employed in order to demonstrate how the concepts and the interconnectedness of han and relationality are being played out in the minds of Korean/Asian North American women. Some practical suggestions are offered for preachers, Bible teachers, pastoral counselors, and caregivers in assisting Korean/Asian North American women with their hermeneutical processes.
STUDENTS' PERCEPTION OF JIMMY CARTER AND THE IDEAL SELF

Sunmy.-The Activity Vector Analysis was administered to 97 junior college students, with instructions to check those words which they felt were descriptive of Jimmy Carter. These same students were again uked to check those words which they felt were descriptive of the Ideal Self or Perfect Person. The data yielded two distinct clusters: (1) around AVA Pattern 6617 for Carter, which correlates .69 with the "Business Executive" profile, and ( 2 ) around AVA Pattern 2972 for the Ideal Self, which correlates .80 with the "Perfect Person'' profile. The correlation between che Carter profile and the Ideal Self profile is -.45, suggesting lack of congruence between the rwo perceptions.
An extension of Edelstein's theorem to a uniform space

The paper contains fixed point theorems of Edelstein's type for contractive mappings in (η,ϕ)-chainable uniform spaces.
Salvage cytoreductive surgery for recurrent endometrial cancer

Abstract Objective To determine the survival impact of salvage cytoreductive surgery, and other prognostic variables, among patients with recurrent endometrial cancer. Methods All patients diagnosed with endometrial cancer recurrence between 7/1/97 and 6/30/05 were retrospectively identified from the tumor registry database. Demographic, pathological, and clinical data were abstracted from the medical record. Survival estimates were calculated using the Kaplan and Meier method. Univariate and multivariate regression analyses were used to identify characteristics associated with overall survival from time of recurrence. Results Sixty-one patients were identified with endometrial cancer recurrence a median of 18.5 months after initial diagnosis. Median age at recurrence was 63 years, and the median post-recurrence follow-up time was 22.0 months. Thirty-five patients underwent salvage cytoreductive surgery and had a median survival time of 28.0 months, compared to 13.0 months for patients treated non-surgically ( P P = 0.0005). On multivariate analysis, salvage surgery and residual disease status were significant and independent predictors of post-recurrence survival. Conclusions Complete salvage cytoreductive surgery for recurrent endometrial cancer is associated with prolonged post-recurrence survival compared to patients left with any gross residual disease. Additional studies are warranted to define appropriate surgical indications and selection criteria.
Melanin synthesis is associated with changes in hyphopodial turgor, permeability, and wall rigidity in gaeumannomyces graminis var. graminis.

Mycelia of Gaeumannomyces graminis var. graminis form large cells called hyphopodia with deeply lobed, melanized walls. Like appressoria produced by other pathogens, hyphopodia develop on hydrophobic surfaces, but it is not clear that hyphopodia function as platforms for host penetration. In appressoria, melanin synthesis is linked to the generation of enormous turgor pressures that provide the necessary force for plant penetration. In the present study, hyphopodial turgor was measured in a wild-type strain of G. graminis var. graminis, a mutant exhibiting constitutive synthesis of melanin (referred to as the dark mutant), and a melanin-deficient strain (thr). These experiments demonstrate that hyphopodia of the wild-type strain generate higher pressures than the dark mutant and that nonmelanized thr hyphopodia generate minuscule internal pressures. Melanization of the wall is also associated with an increase in its rigidity. These data correlate with differences in wall permeability consistent with a recent model for turgor generation by appressoria.
Strengths Use and Life Satisfaction: A Moderated Mediation Approach

This manuscript examined mediators and moderators that may explain the link between strengths use and life satisfaction with a sample of 224 undergraduate students. A mediation model was tested hypothesizing that self-esteem would partially mediate the strengths use-life satisfaction link. Additionally, a moderated mediation model was tested examining positive affect as a moderator within the hypothesized model. Results suggest that a partial reason strengths use related to life satisfaction was due to an increased level of self-esteem. However, this finding must be taken in light of our mediation analysis being conducted with cross-sectional data, a limitation discussed in further detail. Furthermore, positive affect moderated the self-esteem-life satisfaction link, such that the link was stronger for individuals with low and moderate levels of positive affect. This manuscript addresses a major gap in the positive psychology literature by attempting to examine why strengths use relates to increased life satisfaction. Implications for research are discussed.
Designing biomaterials to direct biological responses.

We have set forth a design strategy for creating biomimetic materials that direct the formation of tissue surrounding implants or regeneration within porous scaffolds. Our studies have established that heterogeneous mimetic peptide surfaces (MPS) containing both the -RGD- (cell-binding) and-FHRRIKA- (putative heparin-binding) peptides, unique to BSP, in the ratio of 75:25 (MPS II) or 50:50 (MPS III) proved to be more biologically relevant and specific for RCO cell function. The initial response of human osteoblast-like cells to these surfaces was mediated by the collagen (alpha 2 beta 1) and vitronectin receptors (alpha v beta 3), whereas the vitronectin receptor alone dominated longer-term events (> 30 min). MPS II and III surfaces enhanced cell spreading and long-term events such as mineralization of the extracellular matrix compared to homogenous peptide surfaces and controls. Furthermore, extensive mineralization of the ECM deposited by RCOs occurred when the peptide was coupled to an interfacial interpenetrating polymer network (IPN) that resisted protein deposition (i.e., non-specific adsorption) and fouling. Work on thermo-reversible P(NIPAAm-co-AAc) hydrogels demonstrated the ability to create materials that can be delivered to the body in a minimally invasive manner and support tissue regeneration. These hydrogels can be modified to incorporate biofunctional components such as the biomimetic peptides, theoretically enhancing their ability to foster tissue regeneration. These results suggest that biomaterials can be engineered to mimic ECM components of bone (e.g., various organs) by grafting peptides in the appropriate ratios of the cell and heparin-binding domains, and ultimately modulate the expression of the osteoblast cell phenotype. Approaches similar to the one presented in this work can be used to design materials for hybrid artificial organs and other tissues.
Effect of Sodium Hydroxide, Calcium Hydroxide, and Potassium Hydroxide on Debranning of Corn

ABSTRACT The effect of sodium hydroxide, calcium hydroxide, and potassium hydroxide, and processing conditions (alkali concentration and soaking time) on corn debranning was studied at a temperature of 55°C. Fiber yield, soluble dry matter loss, and total dry matter removed were determined for different alkalies and processing conditions. Sodium hydroxide and potassium hydroxide resulted in maximum fiber yields of 3.38 and 3.48%; maximum soluble dry matter loss of 7.63 and 10.96%; and maximum total dry matter removed of 10.52 and 13.26%. Calcium hydroxide at 6% concentration level resulted in negligible fiber yield, soluble dry matter loss, and total dry matter removed with soak times up to 16 hr. Sodium hydroxide has higher debranning action than potassium hydroxide at 3 and 6% concentration levels; whereas, at 9% concentration level, potassium hydroxide has higher debranning action.
Angiography and magnetic resonance imaging of aortic dissection

This review article describes and illustrates the role of angiography and magnetic resonance imaging in the evaluation of aortic dissection. Clinical findings, complications, classification, and treatment of dissection are reviewed as well.
Have personal statements become impersonal? An evaluation of personal statements in anesthesiology residency applications

Abstract Study Objective To evaluate personal statements submitted to a major academic anesthesiology program to determine the prevalence of common features and overall subjective quality, and to survey anesthesiology program directors as to how they utilized these statements during the resident selection process. Design Structured analysis of de-identified personal statements and Internet-based survey of program directors. Setting Large academic anesthesiology training program. Subjects 670 applicant personal statements and academic anesthesiology program directors. Measurements Prevalence of 13 specific essay features and 8 quality ratings were calculated for the essays and correlated with other aspects of the residency application, as abstracted from the Electronic Residency Application Service (ERAS) files. A 6-question survey regarding use of personal statements was collected from program directors. Main Results 70 of 131 program directors queried responded to our survey. Interest in physiology and pharmacology, enjoyment of a hands-on specialty, and desire to comfort anxious patients were each mentioned in more than half of the essays. Candidates invited for an interview had essays that received higher quality ratings than essays of those not invited ( P = 0.02 to P Conclusion The data showed a high prevalence of common features found within personal statements and a general ambivalence amongst those program directors for whom the statements were intended.
'Biological' depression; because sleep fails?

Although converting-enzyme inhibition is of established value in the management of patients with severe chronic congestive heart failure, troublesome adverse reactions occur frequently during the course of treatment and may cause physicians to interrupt effective therapy. The three most common adverse reactions that are seen in patients with heart failure following treatment with captopril and enalapril (symptomatic hypotension, functional renal insufficiency, hyperkalaemia) are predictable consequences of interfering with the homeostatic functions of the renin-angiotensin system, which evolved millions of years ago to preserve life in sodium-depleted states. It is not surprising, therefore, that these untoward effects can be prevented or reversed by increasing the dietary intake of salt or reducing the dose of concomitantly administered diuretics; their occurrence rarely requires discontinuation of drug therapy. Recognition of this link between sodium balance and the adverse effects of converting-enzyme inhibition is important, because most patients with severe heart failure who experience such untoward reactions can nevertheless be expected to improve clinically during long-term therapy, if effective treatment is not interrupted.
Sensorineural hearing loss in patients with cystic fibrosis.

Objective: To determine the prevalence of sensorineural hearing loss (SNHL) in cystic fibrosis (CF) patients and its relationship to antibiotic use.Study Design: Case series with chart review.Setting: Tertiary care pediatric hospital.Subjects and Methods: We reviewed the medical records of CF patients seen in our children's hospital between March 1994 and December 2007. Data collected included patient demographics, audiograms, tympanograms, genotype, and use of potentially ototoxic antibiotics.Results: Seven of 50 (14%) patients had SNHL. Three percent of patients who received ≤10 courses of intravenous aminoglycosides had SNHL versus 43 percent of those who received >10 courses (P < 0.01). No patients who received five or fewer courses of nasal irrigation with aminoglycosides had SNHL versus 23 percent of those who received more than five courses (P < 0.05). Nine percent of patients who received five or fewer courses of macrolides had SNHL versus 60 percent of those who received more than five courses (P...
Process-structure-microstructure relationship in hot strip rolling of steels using statistical data mining

Abstract Mathematical models have been widely used for prediction of microstructure and mechanical properties in hot rolling of strip. To accurately predict these characteristics, it is necessary to create models that can replicate thermomechanical state of material and its evolution during processing. This paper presents development of a hybrid model that uses mills setting and real time plant data such as chemical composition; forces and temperatures; and integrates them with empirical relationships of material evolution to predict quality attributes. This information is combined with non-linear statistical data mining models to create online tool that predicts properties of individual coil. Case study from Steel Plant is presented that illustrates implementation, calibration and validation of this model across different materials grades.
High pressure-induced anomalous behavior in the mixed-valent superconductor CeRu3Si2

Abstract Electrical resistivity of CeRu 3 Si 2 has been measured from 290 to 1.1 K under high pressure up to 150 kbar. The initial strong suppressions in the resistivity and its T 2 -dependence, and the enhancement of T c were abruptly replaced by a pressure insensitive state above ≈ 30 kbar which is presumably tetravalent.
Changing boundaries in psychiatry.

M any psychiatrists wonder if psychiatry has sowed seeds in the past that will destroy its future. Some think it may be torn apart in a civil war between neurobiological research and psychodynamic or psychosocial extremists. The expanse of the specialty is great, and difficuk to protect. As we understand more about the neural bases of mental illnesses/the boundaries between psychiatry and neurology become more permeable. Some fear psychiatry may abandon or lose its identity altogether, transplanted to the realm of clinical psychology. Psychopharmacological management, a complex skill that requires specialty training, is sometimes done by family practitioners. Will there be anything left of psychiatry 50 years from now? Or will a few psychiatrists remain, writing increasingly large numbers of prescriptions for patients they see for increasingly short periods of time? Despite this pessimistic scenario, I believe that psychiatry has a great future. First, psychiatrists specialise in treating mental illnesses, diseases that may ultimately arise from brain but that are expressed as mind. Mental illnesses are among the most important medical diseases by any measure chosen: morbidity, mortality, economic cost, or cost in personal suffering. Mental illnesses may ultimately be understood on the -basis of brain mechanisms, but they afflict individuals who live in personal and social contexts, and treatment must be provided in those contexts. Understanding how schizophrenia arises from the brain does not equip one for talking with and caring for a delusional or suicidal person. Only psychiatrists are uniquely trained to work at the complex interface between brain, the individual, and society. Second, psychiatry has lost its aura of hopelessness, as newer and better treatments have been developed. Its therapeutic future is even more promising. At present psychiatrists are able to offer complete remission of symptoms to many patients who present with syndromes such as anxiety, panic, or depression, and substantial improvement to most others. Most patients with psychotic disorders now live in the community. New "atypical neuroleptic" drugs markedly reduce symptoms with minimal side-effects. The promise of early and rapid pharmacological intervention combined with sensitive psychosocial and psychotherapeutic treatments holds out substantial hope of effective reintegration into the community and the possibility of a productive life, Increasingly, pharmacological treatments are rationally rather than empirically derived, based on our rapidly growing knowledge of neurotransmitter distribution and function, signal transduction, neural circuits and systems, and cognitive neuroscience. The partnership between clinical and basic research in neuroscience has given psychiatry a solid foundation for understanding how treatments work. In the future, this will lead to Changing boundaries in psychiatry
Selective catalytic reduction of nitric oxide with ethanol/gasoline blends over a silver/alumina catalyst

Abstract Lean gasoline engines running on ethanol/gasoline blends and equipped with a silver/alumina catalyst for selective catalytic reduction (SCR) of NO by ethanol provide a pathway to reduced petroleum consumption through both increased biofuel utilization and improved engine efficiency relative to the current stoichiometric gasoline engines that dominate the U.S. light duty vehicle fleet. A pre-commercial silver/alumina catalyst demonstrated high NO x conversions over a moderate temperature window with both neat ethanol and ethanol/gasoline blends containing at least 50% ethanol. Selectivity to NH 3 increases with HC dosing and ethanol content in gasoline blends, but appears to “saturate” at around 45%. NO 2 and acetaldehyde behave like intermediates in the ethanol SCR of NO. NH 3 SCR of NO x does not appear to play a major role in the ethanol SCR reaction mechanism. Ethanol is responsible for the low temperature SCR activity observed with the ethanol/gasoline blends. The gasoline HCs do not deactivate the ethanol SCR activity, but they also do not appear to be significantly activated by the presence of ethanol.
Review of John Thatamanil, The Immanent Divine: God, Creation, and the Human Predicament

John Thatamanil’s The Immanent Divine: God, Creation, and the Human Predicament (Fortress, 2006) excels in a new stage of inter-religious work: comparative theology for the sake of constructive theology. A major claim is that while initial comparative categories often illuminate what religions hold in common, so as to promote mutual acceptance, such categories over time fall short. Mutual communication must be deepened by mutual critique leading, at least ideally, to mutual transformation. Comparative work picks up steam when descriptive honesty, and the desire for theological coherence show how initial categories fail to be applicable or adequate or both. However, as thinkers continue to seek a consistent common vocabulary, they can come to rethink not only others’ tradition but their own (Thatamanil frequently footnotes Robert Neville and Francis X. Clooney for this approach—not surprising given their earlier joint participation in the Comparative Religions Project centered at Boston University. He also turns to John Cobb to develop the concept of mutual transformation).
Measurements of serum gentamycin levels by rapid tests.

Gentamicin is a very useful antimicrobial agent for the treatment of serious infections caused by gram-negative bacteria. However, it's low therapeutic index and potential ototoxic and nephrotoxic side effects necessitate frequent determinations of serum concentration to assist in maintaining therapeutic levels and avoiding toxic levels. Two bioassays and a latex agglutination inhibition card (LAIC) test were evaluated to determine gentamicin levels in nearly 100 patient sera. Results were compared with a radioimmunoassay (RIA). Two bioassays, the Bio-Monitor and the GentaSak, gave correlation coefficients of 0.987 and 0.982, respectively. The correlation coefficient for the LAIC test was 0.987. All three tests compared well with RIA in accurately detecting gentamicin levels in patient as well as simulated sera. The LAIC test, however, was more rapid, giving results within half an hour whereas bioassays required 6–8 hours for completion. The LAIC test was also found to be more economical. It provides a suitable alternative to RIA procedures in small laboratories and for performing ‘stat’ tests since batching is not necessary.
Chemical toxicity on coral reefs: Bioassay protocols utilizing benthic foraminifers

Coral-reef communities worldwide are in decline and one category of threats is chemical pollution. Although the Loop Current ultimately isolated the Florida reef tract from oil and oil dispersants in the aftermath of the Deepwater Horizon oil spill in 2010, the initial threat of exposure highlighted the need for reliable bioassay protocols for predicting the effects of chemical pollutants on coral-reef communities, as well as in monitoring possible exposure. Amphistegina spp. are relatively large, benthic, shelled protists (Class Foraminifera) that are common on coral reefs at euphotic depths worldwide. These foraminifers harbor algal symbionts in a relationship analogous to that of corals that host zooxanthellae, making such foraminifers useful proxies for responses of zooxanthellate corals to environmental insults. Amphistegina and other large foraminifers are easy to collect and work with in statistically rigorous sample sizes, features that have led to their use as general bioindicators of reef water quality. The goal of this study was to develop bioassay protocols for chemical pollutants utilizing Amphistegina gibbosa d'Orbigny, the species found ubiquitously on Caribbean and western Atlantic reefs. A protocol was developed to identify the 48-h Lethal Concentration (LC) 50, the concentration of a test chemical in seawater that killed 50% of the specimens during 48-h exposure. Two chemicals found in oil dispersants employed in the clean-up efforts in the Gulf of Mexico, propylene glycol and 2-butoxyethanol, were used as test chemicals. Some individuals, which had appeared to be dead at the end of the 48-h exposure period, recovered following rinsing and removal to clean seawater. This observation required further definition of an Acute Concentration (AC) 50, the concentration of chemical in seawater that killed or rendered inactive 50% of the specimens during a 48-hour exposure. We also evaluated several indicators of chronic effects of the short-term exposure. All concentrations of propylene glycol tested resulted in significantly higher incidences of bleaching (color loss in the foraminifers due to loss of, or damage to, algal symbionts). As bleaching is a common stress response in zooxanthellate corals, even short-term exposure to dispersant chemicals may increase susceptibility to bleaching.