cssi/SciSciGPT-SciSciNet huggingface dataset:
Contingency management of adherence to a complex medical regimen in an elderly heart patient

This research sought to determine whether token reinforcement could improve an elderly heart patient's adherence to his complex medical regimen. Using a multiple-baseline and reversal single-case experimental design, it was demonstrated that the reinforcement contingency was responsible for increasing his walking to more than twice per day, consumption of orange juice to an average of almost three glasses per day, and consumption of three separate pills three times per day. A cessation of angina and an improvement in family relationships also occurred.
Association of aerobic fitness with pulse rate and subjective responses to psychological stress.

Ten high fit and 10 low fit subjects first sat quietly during a baseline period and then participated in a mildly stressful task (recall of digits backwards). Pulse rates and levels of subjective arousal were assessed during the baseline period and during the task performance period. Initial analyses indicated that task performance resulted in general increases in pulse rates, subjective cognitive arousal, and subjective somatic arousal. More importantly, it was found that high fit subjects evinced a smaller pulse rate increase in response to stress than did low fit subjects, but the high and low fit subjects did not differ in their subjective responses to stress. These results are consistent with a growing body of research which indicates that a high level of aerobic fitness is associated with reduced physiological reactivity to psychological stress.
Organic Sublimity: a Kantian Exploration in Aesthetic Appreciation

You are standing in the redwood forest of California, craning your neck to see the top of the giant sequoias. You marvel at their grandeur, as the trees seem to pierce the sunny clouds, but you might find the sequoias even more marvellous if you knew they were over 200 feet high. And wouldn't you stand in still greater awe if you realized that these trees are more than 2,000 years old? Knowing the age of sequoias and other living things can be the basis of a distinctive aesthetic experience – the organically sublime.
Late haemodynamic and functional consequences of radial artery removal on the forearm circulation

Background: We aimed at evaluating the late haemodynamic and functional consequences on the forearm circulation of radial artery removal for coronary artery bypass grafting. Methods: Ten years after surgery we performed basal and stress echo-Doppler evaluation of the forearm circulation, baseline and stress transcutaneous oxymetry and determination of reactive oxygen metabolites in the operated and control arm in 20 asymptomatic patients submitted to radial artery removal. Results: The peak systolic velocity of the ulnar artery of the operated side was significantly higher than the control site. Transcutaneous oxymetry revealed asymptomatic hand ischemia at moderate level of muscular effort in the operated arm, but reactive oxygen metabolites measurement did not differ between the two arms. Conclusions: Even in patients with good ulnar compensation, radial artery removal leads to subtle degree of hand ischemia in conditions of sustained muscular effort. Although the clinical significance of this observation remains to be determined, this finding can have important implications for conduit selection in patients involved in manual activities. © 2007 Elsevier Ireland Ltd. All rights reserved.
Stories as informal lessons about security

Non-expert computer users regularly need to make security-relevant decisions; however, these decisions tend not to be particularly good or sophisticated. Nevertheless, their choices are not random. Where does the information come from that these non-experts base their decisions upon? We argue that much of this information comes from stories they hear from other people. We conducted a survey to ask open- and closed- ended questions about security stories people hear from others. We found that most people have learned lessons from stories about security incidents informally from family and friends. These stories impact the way people think about security, and their subsequent behavior when making security-relevant decisions. In addition, many people retell these stories to others, indicating that a single story has the potential to influence multiple people. Understanding how non-experts learn from stories, and what kinds of stories they learn from, can help us figure out new methods for helping these people make better security decisions.
Rotation reveals the importance of configural cues in handwritten word perception

A dramatic perceptual asymmetry occurs when handwritten words are rotated 90 ° in either direction. Those rotated in a direction consistent with their natural tilt (typically clockwise) become much more difficult to recognize, relative to those rotated in the opposite direction. In Experiment 1, we compared computer-printed and handwritten words, all equated for degrees of leftward and rightward tilt, and verified the phenomenon: The effect of rotation was far larger for cursive words, especially when they were rotated in a tilt-consistent direction. In Experiment 2, we replicated this pattern with all items being presented in visual noise. In both experiments, word frequency effects were larger for computer-printed words and did not interact with rotation. The results suggest that handwritten word perception requires greater configural processing, relative to computer print, because handwritten letters are variable and ambiguous. When words are rotated, configural processing suffers, particularly when rotation exaggerates the natural tilt. Our account is similar to theories of the “Thatcher illusion,” wherein face inversion disrupts holistic processing. Together, the findings suggest that configural, word-level processing automatically increases when people read handwriting, as letter-level processing becomes less reliable.
Intelligent strategies for secure complex systems integration and design, effective risk management and privacy

There has been increasing challenges in the effective design of engineering complex integrated systems and Systems-of-systems in engineering and network systems. This is largely due to the integration of complex large data transfers across multiple zones of systems and network integration. The increase in transmission of highly sensitive data and challenges of data protection and of privacy, data loss prevention has major significant implications for systems engineering, systems integration, and systems analysis, design and validation. Furthermore, the design and development of complex integrated systems engineering and network systems lack effective transparency, auditability, validation and implementation of adequate security measures for transfers of highly sensitive metadata across global networks using third party and outsourced networks and the Internet and global privacy regulatory requirements for such data transfer across international borders. The major problem with current state of art approaches of controls for global critical infrastructures of Virtual Private Networks (VPN) depend on inadequate third-party systems. Thus current approaches lack transparency, auditability and validation of the implementation of adequate privacy and security controls for data transfers of highly sensitive metadata across global networks. The additional problem of obscurity has resulted in increasing concealing of unauthorized access, identity thefts, privacy and security breaches of highly sensitive data, interception through the man-in-the-middle and intermediary systems. The paper examines the effectiveness, resiliency, robustness, scalability and adaptability in the design, safety, security and usability of engineering complex integrated systems and network systems for complex large data transfers across multiple zones of systems and network integration and security.
β-Blocker Therapy Is Not Associated With Adverse Outcomes in Patients With Pulmonary Arterial Hypertension A Propensity Score Analysis

Background—The safety of β-blockers in patients with isolated right ventricular failure because of pulmonary arterial hypertension (PAH) is unclear. Methods and Results—We studied 564 PAH patients (total cohort) referred to our center from 1982 to 2013. Propensity score-matching was used to match pairs of PAH patients with and without β-blocker use (matched cohort). We compared all-cause mortality between the groups in the total cohort and the matched cohort using bootstrap validation, Kaplan–Meier, and Cox proportional hazard analyses. Seventy-one of the 564 patients in the total cohort were on β-blockers. They were older, had higher prevalence of comorbidities, and were more often on diuretics, digoxin, and angiotensin converting enzyme inhibitors. The severity of PAH and right ventricular failure was similar between those with and without β-blocker use. After propensity matching, 63 patients with β-blocker use were compared with 51 patients without β-blocker use. During a median follow-up time of 4.8 y...
How megalin finds its way: identification of a novel apical sorting motif. Focus on "Identification of an apical sorting determinant in the cytoplasmic tail of megalin".

whenever a cell employs the sequences encoded within its genome to direct the synthesis of a new polypeptide, it solves a fundamental problem in information processing. Decades of experiments have defined many of the mechanisms through which cells translate their genetic information into structural
Consequences of Being Bullied Results From a Longitudinal Assessment of Bullying Victimization in a Multisite Sample of American Students

Bullying victimization is part of the adolescent experience in most societies, yet little is known about its consequences. In this article we utilize a multisite, longitudinal data set to examine the effects of being bullied. We also explore definitional and measurement issues that confound this line of research. While some researchers have relied on a single/generic item to measure bullying, others have focused on behaviorally specific items. In addition, most prior research on bullying has relied on cross-sectional data, thereby restricting researchers’ ability to examine the consequences of prior victimization. Using three waves of data, we create a typology of victimization (nonvictims, intermittent victims, and repeat victims) that allows us to establish correct temporal ordering to examining the effects of victimization on subsequent attitudes. Importantly, we assess the consequences of bullying victimization using both a single-item indicator and a composite measure consisting of behaviorally specific questions.
Mobile Computing for Field Operator Control: Petrochemical Plant Operations Case Study

OCCUPATIONAL APPLICATIONS This study found that the use of a mobile computing system for field operations in a petrochemical plant allowed operators to get information “at a glance” from various process variables, which could substantially improve operators’ situational awareness. Use of mobile devices can provide an operator with the flexibility of interacting through touch and easy in/out zooming, reducing musculoskeletal stress and facilitating improved human–computer interaction. TECHNICAL ABSTRACT Background: Process control and maintenance systems have been used in the petrochemical and refining industry for improving operator performance and workforce efficiency. Design aspects, associated with retrieving and reviewing information, directly affect the ability to make timely and quality decisions in high-stakes environments, such as a petrochemical plant where time-critical decision-making contexts are involved. Hence, there is a need to understand how advances in mobile computing, sensor technologi...
The (In)Visible People in the Room: Men in Women's Studies

Men who take Women’s Studies classes often exist in a paradoxical space, the physical bearers of much that is discussed within the room while also the symbol of that which chooses not to participate. This status of (in)visibility, in which men find themselves simultaneously the most conspicuous and the most absent members of the discourse, has led to a situation in which feminist theorizing has not kept up with practical reality. In this article, part narrative and part critical examination, (in)visibility is analyzed as both a phenomenon and an opportunity for the discipline and the theory to move forward toward more productive coalition while keeping lived realities and experiences squarely in the forefront.
Topical Anesthesia With EMLA does Not Decrease Pain During Vasectomy

Purpose: Previous studies show conflicting results of the ability of EMLA (eutectic mixture of local anesthetics) to decrease pain during vasectomy. We examined the effectiveness of EMLA cream to decrease pain in patients undergoing bilateral percutaneous no-scalpel vasectomy.Materials and Methods: A prospective study was performed in which 316 patients used EMLA cream (178) or no topical anesthesia (138) before vasectomy. EMLA cream was applied by patients 1 hour before the scheduled time of surgery. Bilateral percutaneous no-scalpel vasectomy was then performed in the 2 groups with local infiltration of 1% lidocaine into the scrotal wall and vasal sheath. Following the procedure patients were asked to rate their associated pain using a visual analog scale. Statistical analysis was performed using the 2-sided Student t test.Results: Mean patient age was similar in the groups with and without EMLA (39.1 and 39.0 years, respectively). No significant difference in mean visual analog pain scores were noted b...
Understanding NSF funding opportunities

This session highlights programs in the National Science Foundation's (NSF) Education and Human Resources (EHR) and Computer and Information Science and Engineering (CISE) directorates. The focus is on providing descriptions of several programs of interest to college faculty, and discussing the requirements and guidelines for programs in these areas. It includes a description of the proposal and review processes as well as strategies for writing competitive proposals. Participants are encouraged to discuss procedural issues with the presenters.
Comparison of calcite + dolomite thermometry and carbonate + silicate equilibria: Constraints on the conditions of metamorphism of the Llano uplift, central Texas, U.S.A.

Temperatures based on the composition of calcite coexisting with dolomite (calcite + dolomite thermometry) range from 475 to 600°C for 63 marbles from the Llano uplift of central Texas. The highest temperatures, -600°C, were obtained by carefullyreintegrating calcite containing exsolved lamellae of dolomite. In some cases, these high temperatures were determined for marbles that contain an isobarically invariant assemblage consisting of calcite + dolomite + tremolite + diopside + forsterite. At a pressure of 3 kbar, these five minerals are stable at 630 OCand Xco, = 0.62. In contrast, relatively low calcite + dolomite temperatures of 475-480 °Cwere obtained for marbles containing the assemblage calcite + dolomite + tremolite + talc. This talc-bearing assemblage is stable at ~475 OC, depending on fluid composition, at a pressure of 3 kbar. Additional isobarically univariant equilibria are stable at intermediate temperatures (generallybetween 535 and 630 0q, and these are also generallyconsistent with results obtained from calcite + dolomite thermometry. Agreement between the calcite + dolomite temperatures and those inferred from silicate + carbonate equilibria in the marbles indicates that the temperatures generally reflect peak conditions of metamorphism, although some resetting has occurred. The marbles having the highest calcite-dolomite temperatures, as well as those containing the hightemperature isobarically invariant assemblage, are generally found close to post-tectonic pluton contacts, indicating that some of the amphibolite-facies assemblagesare related to the emplacement ofthe granitic intrusions. Relatively low temperatures are recorded within approximately 2 km of pluton contacts, suggestinga possible thermal aureole. However, relatively high temperatures of 550-600 °C are recorded in marbles that are not spatially related to post-tectonic granites (>2 km from pluton contacts). These temperatures may be relicts of an earlier metamorphic event, although they could be related to granites that were emplaced above or below the current erosional level.
On measures of gametic disequilibrium.

Various measures have been proposed for characterizing the statistical association that arises between alleles at different loci. Hedrick has compared these measures with the standardized measure D' proposed by Lewontin on the grounds that this latter measure is independent of allele frequency. Although D' has the same range for all allelic frequencies, in fact, D' is not "independent" of allele frequency, and no measure with that general property is possible for the multilocus association problem. The insolubility of this problem arises from the ill-defined nature of general "association."
Subpicotesla atomic magnetometry with a microfabricated vapour cell

Highly sensitive magnetometers capable of measuring magnetic fields below 1 pT have an impact on areas as diverse as geophysical surveying1, the detection of unexploded ordinance2, space science3, nuclear magnetic resonance4,5, health care6 and perimeter and remote monitoring. Recently, it has been shown that laboratory optical magnetometers7,8, based on the precession of the spins of alkali atoms in the vapour phase, could achieve sensitivities in the femtotesla range, comparable to9,10,11,12, or even exceeding13, those of superconducting quantum interference devices6. We demonstrate here an atomic magnetometer based on a millimetre-scale microfabricated alkali vapour cell with sensitivity below 70 fT Hz−1/2. Additionally, we use a simplified optical configuration that requires only a single low-power laser. This result suggests that millimetre-scale, low-power femtotesla magnetometers are feasible, and we support this proposition with a simple sensitivity scaling analysis. Such an instrument would greatly expand the range of applications in which atomic magnetometers could be used.
Staggered Gain for 100+ GHz Broadband Amplifiers

A broadband amplifier is realized with cascaded stagger-tuned stages that are equalized for high bandwidth and low gain ripple. The staggered frequency response is demonstrated to improve the transimpedance limit of active circuits. The staggered response is demonstrated with a Darlington feedback amplifier and a constructive wave amplifier, which achieves low group delay. The broadband amplifier is implemented in a 0.12-μm SiGe BiCMOS process and achieves a 3-dB bandwidth of 102 GHz. The gain is 10 dB with 1.5-dB gain-ripple and group-delay variation under ±6 ps over the entire 3-dB bandwidth. The chip occupies an area of 0.29 mm2 including the pads and consumes 73 mW from a 2-V supply.
Acquisition of a Lexicon from Semantic Representations of Sentences

A system, WOLFIE, that acquires a mapping of words to their semantic representation is presented and a preliminary evaluation is performed. Tree least general generalizations (TLGGs) of the representations of input sentences are performed to assist in determining the representations of individual words in the sentences. The best guess for a meaning of a word is the TLGG which overlaps with the highest percentage of sentence representations in which that word appears. Some promising experimental results on a non-artificial data set are presented.
GEOGRAPHIC INFORMATION SCIENCE AND SYSTEMS FOR ENVIRONMENTAL MANAGEMENT

▪ Abstract The geographic context is essential both for environmental research and for policy-oriented environmental management. Geographic information systems are as a result increasingly important computing applications in this domain, and an understanding of the underlying principles of geographic information science is increasingly essential to sound scientific practice. The review begins by defining terms. Four major sections follow that discuss advances in GIS analysis and modeling, in the supply of geographic data for GIS, in software design, and in GIS representation. GIS-based modeling is constrained in part by architecture, but a number of recent products show promise, and GIS continues to support modeling through the coupling of software. The GIS data supply has benefited from a range of new satellite-based sensors and from developments in ground-based sensor networks. GIS software design is being revolutionized by two developments in the information technology mainstream: the trend to componen...
Effect of pelleted high-oil canola meal from on-farm biodiesel production on rumen fermentation in lactating Holstein dairy cows

Four lactating, ruminally cannulated Holstein cows (DIM ≥ 50; ≥ second lactation) were paired by milk production and used in a switchback design to compare ruminal fermentation response to a diet containing 7% pelleted, high-oil canola meal (HOCM) versus a control diet (CONT). The CONT diet was made of corn silage, alfalfa haylage, wheat straw, and the concentrate. The HOCM diet contained the same ingredients as the CONT except sunflower seeds and a portion of soybean meal were replaced with pelleted, high-oil canola meal in the concentrate. The canola pellet contained 16.6% crude fat and 37.3% CP. Diets were formulated to be isonitrogenous and isocaloric. The last day of each 21-d switchback period was used to collect ruminal fermentation data. Ruminal fluid samples were collected through the cannula at 0, 2, 4, 6, and 8 h after feeding. Cows were housed in a tie-stall barn, and diets were delivered as a TMR once daily at 1000 h to achieve ad libitum intake (5% orts). Daily DMI and milk production data were recorded during the entire feeding period. There were no differences (P ≥ 0.29) between DMI, milk yield, and efficiency of milk production of cows fed the HOCM and the CONT diets. Ruminal acetate, butyrate, total VFA, and pH were not affected (P ≥ 0.37) by diets. Ruminal propionate tended to be greater (P = 0.09) in cows fed HOCM. Adding 7% of pelleted, high-oil canola meal to lactating Holstein dairy cow diets did not adversely affect ruminal fermentation.
Serum cholesterol determinations as affected by vitamin A.

Summary1. A study was made of the effects of various levels of Vit. A in the serum on total cholesterol as determined by a method using a ferric chloride color reagent and a saponification-extraction method. 2. Comparison between the 2 methods showed that the Vit. A must be separated from the serum before making total cholesterol determinations by the ferric chloride color reagent method.
A MONOCLONAL ANTIBODY AGAINST RAT CALCITONIN INHIBITS THE GROWTH OF A RAT MEDULLARY THYROID CARCINOMA CELL LINE IN VITRO

Medullary thyroid carcinoma (MTC) cells synthesize large amounts of calcitonin (CT), which serves clinically as a useful tumor marker. To examine the possibility of CT serving as a target in immunotherapy for MTC, we raised and characterized more than 40 monoclonal antibodies (mAbs) against rat CT (rCT). The affinity constants for the mAbs were between 2.8 × 109 and 1.8 × 1011 m−1. Some mAbs react preferentially with solid phase rat CT, but not with liquid phase 125I-labeled rCT. Thirty-nine mAbs cross-react with human CT. We evaluated the antitumor effect of the mAbs in vitro by analysis of [3H]thymidine incorporation into the rat MTC cell line CRL-1607. Some antibodies show an antiproliferative effect, but most are inactive. One mAb (2E5G5, IgG2b), which preferentially reacts with solid phase rCT, but not with liquid phase 125I-labeled rCT, exerts an antiproliferative activity on CRL-1607. At 6.25 × 10−7 m, 2E5G5 killed all of the tumor cells independently of complement in a cytotoxicity assay. We explo...
The fabulous Fibonacci numbers by Alfred Posamentier and Ingmar Lehmann

The fabulous Fibonacci numbers by Alfred Posamentier and Ingmar Lehmann, Amherst, NY, Prometheus Books, 2007, 364 pp, USD $28.00, Hardcover, ISBN 9781591024750. 10.1080/17513470902897569-TMAA_A_389...
The Political Development of Urban Policy: Understanding the Role of Ideas and Institutions Through Intercurrence

Congress authorizes and funds various urban redevelopment programs, and local actors attempt to use these programs to address urban issues and concerns, yet many policies do not live up to expectations. Urban scholars tend to focus on local political or economic arrangements to explain this phenomenon, while public policy scholars emphasize the role of special interest or bureaucratic influence on policy success/failure. In this paper, I suggest a new framework for examining urban policy: intercurrence. I operationalize this theoretical framework, drawn from the political science subfield of American political development (APD), to examine the ideas and institutional ordering mechanisms manifest in the Community Reinvestment Act (CRA). I argue that policy creation and evolution can best be understood by looking at ideas about and the institutional arrangements embedded within urban policy, specifically the relationship between the public and private sectors, between state, local and federal governments, and between the Executive and Legislative branches.
Tu1491 Correlation Between Adenoma Detection Rate (ADR) in Screening Sigmoidoscopy and Screening Colonoscopy

colorectal cancers. According to the current Japanese guideline, additional surgical colectomy with lymph node (LN) dissection should be considered after endoscopic treatment even for cases where the depth of SM invasion is 1000mm or more. However, many patients who underwent additional colectomy didn’t have LN metastasis. This over-surgery problem has become a major issue. Aims: The aim is to investigate whether the depth of SM invasion is an appropriate risk factor for the LN metastasis in SM-invasive colorectal carcinomas. Methods: A total of 20072 colorectal neoplasms excluding advanced cancers have been resected endoscopically or surgically at our unit from April 2001 to May 2013. Of these, 853 SM-invasive cancers were included. Initial or additional surgical colectomy with LN dissection was performed in 567 cases, and of which LN metastasis was found in 52 cases (9.2%). There are two ways to measure the depth of SM invasion. One is to directly measure the vertical distance from the line of muscularis mucosae. The other is, when the line of muscularis mucosae is not easily identified due to cancer invasion, the surface layer of the lesion is used as a baseline. According to this rule, a pathologist in our unit categorized 816 lesions and measured their depth of SM invasion. Then, we analyzed the correlations between the depth of SM invasion and the other pathological factors including LN metastasis. Results: Of 567 lesions, 54 lesions (9.5%) were invaded SM!1000mm and 513 lesions (90.5%) showed SM S1000mm. The average SM depth of the lesions without LN metastasis was 3275.7 2441.4mm and that of the lesions with LN metastasis was 4307.4 2307.0mm. LN metastasis was found in 4 (7.5%) out of 53 lesions with SM! 1000mm and in 48 cases (9.6%) out of 502 lesions with SM S1000mm (pZ0.63). Of these 567 lesions, on the other hand, the muscularis mucosa could be identified in 180 lesions (31.7%). For the other 387 lesions (68.3%), the muscularis mucosa was recognized broken or disappeared respectively and the depth of SM invasion was measured from the surface layer. All the results turned out to be S1000mm. Once the muscularis mucosae was judged to be unclear and the surface layer was applied as the baseline, all the cases would be considered S1000mm. Conclusion: Although SM cancers with LN metastasis invaded actually deeper than the lesions without nodal metastasis, the depth of SM invasion was not a statistically significant risk factor for LN metastasis. How to measure the depth of SM invasion depend strongly on the judgement whether the muscularis mucosa could be identified or not. The reconsideration should be needed concerning the depth of SM invasion.
Frank's Sign

A 59-year-old man with long-standing hypertension presented with exertional chest pain. The patient was noted to have bilateral Frank's sign, a diagonal crease that runs across the earlobe at a 45-degree angle and may be a predictor of coronary artery disease.
Big Data

As data permeates all disciplines, the role of big data becomes increasingly critical. This special theme issue's articles examine big data technology trends that impact databases, algorithms, and applications.
Simultaneous determination of amphetamine homologues in urine by high-performance liquid chromatography with molecularly imprinted solid-phase extraction

Objective:To develop a method for the simultaneous deter mination of amphetamine homologues,such as methamphetamine(MA),amphetamine(AM),3,4-methylenedioxy-N-methamphetamine(MDMA),3,4-methylenedioxy-amphetamine(MDA) and 3-methoxy-4,5-methylenedioxy-amphetamine(MMDA) in urine by high-performance liquid chromatography with molecularly imprinted solid-phase extraction(MISPE).Methods:After the urine samples were mixed with 100 mmol /L ammonium acetate buffer(pH8. 0) and centrifuged at 8000 rpm,the cleanup procedure was optimized on an activating MISPE cartridge with 1. 0% acetate acid/acetonitrile(1 /99,v/v) as elution. The separation was performed on an XBridge RP18 column by a mobile phase consisting of methanol-acetonitrile-100 mmol/L ammonium acetate solution for gradient elution. Detection was carried out by an ultraviolet detector at 215 nm. Results:Calibration curves of the five amphetamine homologues were linear within the range of 0. 05 mg/L ~ 15. 0 mg/L with correlation coefficients more than 0. 999. The limits of quantification(LOQs) were between 0. 017 mg/L ~ 0. 03 mg/L. The extraction recoveries were between 88. 0% ~98. 8%,and the RSDs were less than 5. 0%. Conclusion:This developed method is simple,sensitive and accurate. It is suitable for the detection of the amphetamine homologue residues in biological specimens from drug users.
Syntheses and characterization of the vanadium trimer (V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6(4,4′-bipyridine) and the vanadium hexamer [(V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6]2(μ2-N1,N2-di(pyridin-4-yl)oxalamide)

AbstractReacting VO(acac)2 with six equivalents of dibenzylphosphinic acid in the presence of 4,4′-bipyridine or μ2-N1,N2-di(pyridin-4-yl)oxalamide leads to trimeric (V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6(4,4′-bipyridine) or the hexamer [(V3(μ3-O)O2)(μ2-O2P(CH2C6H5)2)6]2(μ2-N1,N2-di(pyridin-4-yl)oxalamide). The complexes were characterized by spectroscopic (FTIR and 1H NMR spectroscopies), TGA, and by single crystal X-ray diffraction measurements. The structures consist of a planar central core where three vanadium ions are arranged in the form of a quasi-isosceles triangle and contain an interstitial O which is multiply bonded to one V and weakly interacting at different bond distances to the remaining two V ions.
Smile rejuvenation: a methodic approach.

Abstract The innovations in dental restoration materials during the last decade have enabled the clinician to achieve improved aesthetic results. However, dependence on the materials alone does not necessarily produce predictable aesthetic results. As the learning objective, the author discusses the need for a methodic approach, the observation of the intact smile, the dominant position of the maxillary central incisors, and the art of aesthetic integration of the maxillary incisors in proper proportion with the face and stature, thereby producing pleasing sensations in the observer.
Plasmablastic Lymphoma vs Myeloma With Plasmablastic Morphology: An Ongoing Diagnostic Dilemma

Plasmablastic lymphoma (PBL) is an aggressive B-cell lymphoma that shows a plasma cell phenotype while lacking expression of B-cell antigens. Multiple myeloma (MM) is an indolent disorder of plasma cells that may similarly show plasmablastic morphology, thus posing a diagnostic challenge. We present the clinical and pathologic findings of a series of plasmablastic neoplasms. A 10-year retrospective search of our files …
Reconfigurable millimeter-wave antennas using paraffin phase change materials

We report, for the first time, a new class of reconfigurable antennas and RF microsystems developed using paraffin MEMS micro actuators. Paraffin is a phase change material that exhibits 15% volumetric (mechanical) change at approximately 70°C. Unlike traditional electrical phase-change materials (e.g. germanium telluride and vanadium dioxide) operating between quasi-dielectric and quasi-conductor states, paraffin is an organic low-dielectric-loss material (tan δ = 0.008, er = 2.26 at 300 GHz) that undergoes reversible mechanical change. Here, we introduce low-loss thermo-electro-mechanically actuated MEMS capacitors at 100 GHz that are monolithically integrated with antennas. As a demonstration, a reconfigurable slot antenna with 6.7 GHz (92.6 – 99.3 GHz) of continuous frequency tuning is reported. It is also observed that the radiation pattern is not affected by the frequency reconfiguration and the maximum gain of the antenna is constant at 4.5 dBi for the entire frequency band. The proposed paraffin variable capacitors enable realization of wide variety of reconfigurable antennas as well as front-end components such as tunable oscillators at millimeter wave band.
The East Asian International Orders

Wan provides a broad historical institutional account of world political development to contextualize East Asian international relations and the AIIB. There have been entrenched civilizational centers in the Eurasian continent, with China as one of them. With their distinct evolutionary paths, the traditional centers of civilization have had difficulty adapting to democratic institutions and the trend continues. A major institutional development may be simply a functional equivalent resulting from convergent evolution or borrowing from competitors. Political lineage matters in that it dictates distinct mixtures of unique and universal ideational forces and gives clues about the interaction effect. All the civilizational centers view power acquisition as a central objective and use power broadly understood as policy instrument. The AIIB is a symbol of that historical trend.
Replacing metals with alternative plasmonic substances in plasmonics and metamaterials: Is it a good idea?

Metals, which dominate the fields of plasmonics and metamaterials suffer from large ohmic losses. New plasmonic materials, such as doped oxides and nitrides, have smaller material loss, and using them in place of metals carries a promise of reduced-loss plasmonic and metamaterial structures, with sharper resonances and higher field concentration. This promise is put to a rigorous analytical test in this work and it is revealed that having low material loss is not sufficient to have a reduced modal loss in plasmonic structures, unless the plasma frequency is significantly higher than the operational frequency. Using examples of nanoparticle plasmons and gap plasmons one comes to the conclusion that even in the mid-infrared spectrum metals continue to hold advantage over the alternative media. The new materials may still find application niche where the high absorption loss is beneficial, e.g. in medicine and thermal photovoltaics.
Abstract 342: Ultrasound-Enhanced Release of Bevacizumab from Echogenic Liposomes for Therapeutic Inhibition of Atherogenesis

Introduction. Bevacizumab (BEV) is a humanized monoclonal antibody to vascular endothelial growth factor (VEGF) that can ameliorate atheroma progression, the mechanism of which is believed to be through inhibition of neovascularization. Systemically, BEV has multiple adverse effects, which may be diminished in a controlled release delivery vehicle. Hypothesis. The purpose of this study was to test the hypothesis that BEV release from echogenic liposomes (BEV-ELIP) could be enhanced by color Doppler ultrasound (US). Methods. BEV-ELIP were prepared by a rehydration/loading-freeze/thaw-centrifugation-lyophilization method. BEV-ELIP samples were resuspended in 50ml of porcine plasma and divided into two portions, one of which was subjected to 6 MHz color Doppler ultrasound (MI = 0.4) for 5 minutes. After various time intervals, aliquots were fractionated by centrifugation and assayed for immunoreactive BEV with a direct enzyme-linked immunosorbent assay (ELISA). We considered immunoreactive BEV in washed pellet suspensions to represent ELIP surface-exposed VEGF-binding sites. To assure that BEV was accurately measured in plasma, we repeated the release protocol with fluoresceinated BEV (FITC-BEV) loaded into ELIP by the same method; BEV was measured by quantitation of fluorescence emission using a SpectraMax M5 microplate reader. Results. BEV-ELIP encapsulation efficiency was 43.2 ± 9.7% (SD, n = 5); 34.1 ± 29.3% of the encapsulated BEV was spontaneously released within the first 30 minutes. US caused an additional 4.1% of BEV to be released from the surface exposed compartment. Fluorescence measurements indicated that 43.2 ± 6.2% (n = 3) of encapsulated FITC-BEV-ELIP was spontaneously released in 60 minutes and that US caused an additional 5.7% to be released in that period, but, overall, US caused an additional 100 μg of BEV to be released or exposed per aliquot. Conclusions. We have demonstrated that BEV-ELIP retains its VEGF-binding activity in a liposomal formulation and that clinical Doppler US can significantly increase that activity, both by releasing free BEV and by enhancing the surface exposure of the immunoreactive antibody. These results warrant investigation of the formulation’s anti-angiogenic efficacy in vitro and in vivo.
'Autism in Love' Review

This article provides a review of the documentary film 'Autism in Love' by Matt Fuller, a film that profiles the romantic lives of four people affected by Autism Spectrum Disorder (ASD). In addition to an overview of the basic themes of the movie, the review also contains excerpts of an interview with the film’s director.
Effects of Social Norms Information and Self-Affirmation on Sugar-Sweetened Beverage Consumption Intentions and Behaviors

The separate and combined efficacy of a social norms and a self-affirmation intervention to motivate decreased sugar-sweetened beverage (SSB) consumption was examined in two experiments. College students were randomly assigned to receive information about SSB consumption risks, norms, both, or neither. In addition, participants performed either a self-affirmation or control task. Self-affirmation only weakly affected SSB consumption intentions and behaviors. However, participants in Experiment 2 who received risks information, norms information, or both reported greater SSB reduction intentions than did those who received no information. Two-weeks later, those who received both types of information reported more frequent behavior change preparations, and it appears this effect may have been partially mediated by the changes in intentions to reduce SSB consumption.
LTD-RBM: Robust and Fast Latent Truth Discovery Using Restricted Boltzmann Machines

We address the problem of latent truth discovery, LTD for short, where the goal is to discover the underlying true values of entity attributes in the presence of noisy, conflicting or incomplete information. Despite a multitude of algorithms addressing the LTD problem, only little is known about their overall performance with respect to effectiveness, efficiency and robustness. The LTD model proposed in this paper is based on Restricted Boltzmann Machines, thus coined LTD-RBM. In extensive experiments on various heterogeneous and publicly available datasets, LTD-RBM is superior to state-of-the-art LTD techniques in terms of an overall consideration of effectiveness, efficiency and robustness.
Disguising Harms: Talking and Not Talking About It

This chapter discusses how Tyson disguises their actions toward animals and the environment. Unexamined, the passages from Tyson’s website that discuss the environment and animal well-being give the impression that Tyson is proactive and transparent. On closer inspection, we find that Tyson says a lot about their beliefs, but very little about what they are actually doing.
How to prevent mortgage default without skin in the game: Evidence from an integrated homeownership support nonprofit

Abstract We test the assumption that borrowers need sufficient “skin in the game”, or a large down payment, to perform well on their mortgages. To do so, we estimate the effects of a homeownership support organization's attempt to help low- and moderate- income households purchase homes through a range of integrated services, including the provision of a second mortgage that allows for a low down payment with no mortgage insurance. Using client-level data from the homeownership support organization, Homewise, and controlling for income and other demographics, we first show that the organization's clients successfully avoid the savings barrier to home purchase – a barrier which impedes many low-income households from obtaining a mortgage. We then combine Homewise administrative data with CoreLogic and Home Mortgage Disclosure Act (HMDA) data to compare the post-purchase behavior of participating households to those of similar households using a propensity score matching technique. Results indicate that Homewise's clients perform better on their loans than other similar borrowers in their region. For every 100 home purchasers, clients purchasing homes through Homewise have 6.3 fewer 30 day delinquencies in the first two years of their mortgage than a matched comparison group of purchasers, 2.3 fewer 60 day delinquencies, 1.8 fewer 90 day delinquencies, and 1.1 fewer 180 day delinquencies. These results show that with the correct combination of homeownership support services, low- and moderate- income households can sustain a mortgage with a low-down payment.
Association Between Intimate Partner Violence and Breastfeeding Duration: Results From the 2004-2014 Pregnancy Risk Assessment Monitoring System:

Background:Intimate partner violence is a major public health problem that disproportionately affects women. Current literature investigating the relationship between intimate partner violence and ...
Energy-Efficient Data Collection from Wireless Nodes Using Mobile Robots

This work focuses on systems where mobile robots periodically collect data from (static) wireless sensor network nodes. Suppose we are given approximate locations of the static nodes, and an order with which the robot will visit these nodes. We present solutions to the following problems. (i) From the static node’s perspective: given the stochastic nature of the robot’s arrival, what is an energy-efficient strategy to send beacon messages? Such a strategy must simultaneously minimize the robot’s waiting time and the number of beacon messages. (ii) From the robot’s perspective: given the stochastic nature of the wireless link quality, what is an energy-efficient motion strategy to find a good pose (location and orientation) from where the data can be downloaded efficiently? The robot must be able to find such a location quickly but without taking too many measurements so as to conserve the static node’s energy.
Let-7 Sensitizes KRAS Mutant Tumor Cells to Chemotherapy

KRAS is the most commonly mutated oncogene in human cancers and is associated with poor prognosis and drug resistance. Let-7 is a family of tumor suppressor microRNAs that are frequently suppressed in solid tumors, where KRAS mutations are highly prevalent. In this study, we investigated the potential use of let-7 as a chemosensitizer. We found that let-7b repletion selectively sensitized KRAS mutant tumor cells to the cytotoxicity of paclitaxel and gemcitabine. Transfection of let-7b mimic downregulated the expression of mutant but not wild-type KRAS. Combination of let-7b mimic with paclitaxel or gemcitabine diminished MEK/ERK and PI3K/AKT signaling concurrently, triggered the onset of apoptosis, and reverted the epithelial-mesenchymal transition in KRAS mutant tumor cells. In addition, let-7b repletion downregulated the expression of β-tubulin III and ribonucleotide reductase subunit M2, two proteins known to mediate tumor resistance to paclitaxel and gemcitabine, respectively. Let-7 may represent a new class of chemosensitizer for the treatment of KRAS mutant tumors.
Suicide risk among Veteran primary care patients with current anxiety symptoms.

Background Although anxiety is prevalent in primary care, the association between anxiety symptoms and suicide risk remains understudied. Objectives This cross-sectional study aimed to (i) assess the prevalence of suicide risk among Veteran primary care patients with anxiety symptoms and (ii) compare suicide risk between patients with a positive (versus negative) depression screen. Methods Participants were 182 adult primary care patients (84.6% male, Mage = 58.3 years) with current anxiety symptoms, but no psychotherapy in specialty care in the past year, at a Veterans Health Administration medical center in New York. Participants completed self-report measures of anxiety, depression and suicide risk via telephone. Results Forty percent endorsed ≥1 suicide risk item. Suicide risk was more common among those screening positive (versus negative) for depression (50.5% versus 26.5%, χ2 (1) = 10.88; P = 0.001). Participants with a negative depression screen constituted 31% of all those with any suicide risk. Logistic regression revealed that anxiety symptom severity was not associated with suicide risk (P = 0.14) after controlling for age, sex and depression screen status (P = 0.01). Conclusions A substantial proportion of primary care patients with anxiety was classified as at risk for suicide, even in the absence of a positive depression screen. Primary care providers should assess suicide risk among patients with anxiety symptoms, even if the patients are not seeking specialty mental health treatment, the anxiety symptoms are not severe or do not rise to the level of an anxiety disorder, and comorbid depressive symptoms are not present.
Ustekinumab-associated disseminated verrucae

Ustekinumab is a human interleukin (IL)12/23 antagonist with US Food and Drug Administration indications to treat moderate to severe plaque psoriasis, psoriatic arthritis, and Crohn's disease. Because of the blockade of the IL-12/IL-13 pathway, which mediates antitumor and antiviral responses, ustekinumab has significant immunosuppressive characteristics and can lead to an increased risk of infection, reactivation of latent infection, and malignancy in patients. We present a case of a patient with psoriasis and psoriatic arthritis on ustekinumab who had disseminated verrucae shortly after initiating treatment.
Thin Films of Zinc-Doped GaAs by RF Magnetron Sputtering for Use in Photovoltaic Cells

Radio frequency (RF) magnetron sputtering parameters that produce highly crystalline thin films of gallium arsenide (GaAs) were investigated. Literature results were reproduced to determine optimum conditions for sputtering highly crystalline films. At these desirable conditions, a noticeable increase in the Ga:As ratio was discovered, resulting from metallic gallium present on the film surface. A simple HCl treatment was developed to remove the excess gallium and return the film to the stoichiometric ratio of Ga:As. An in-situ zinc doping method was investigated and refined to sputter p-type GaAs films. Hall effect measurements confirmed that the Zn-doped films were p-type and the hole concentration increased with increasing Zn content.
Online Appointment Scheduler: The Perfect Fit for the On-Demand Generation

Column description. Special Libraries, Special Challenges is a column dedicated to exploring the unique public services challenges that arise in libraries that specialize in a particular subject, s...