cssi/SciSciGPT-SciSciNet huggingface dataset:
Diarrhea in Multiple Myeloma: A Review of the Literature

Background One of the most common and inadequately managed symptoms that patients with multiple myeloma (MM) experience as a result of cancer treatment is diarrhea. Diarrhea in patients with MM often is severe enough to warrant dose reduction, delays, or discontinuation of chemotherapy. Short-term diarrhea can occur as a side effect of drugs, such as bortezomib (Velcade®) or panobinostat (Farydak®). Late-onset diarrhea from lenalidomide (Revlimid®) can occur 17-24 months after the start of therapy. Treatment of diarrhea is often by dose reduction and discontinuation of the offending drug. However, the symptom fails to entirely resolve with these interventions and dose reductions place the individual at risk for disease progression. Best practices for diarrhea management in MM are poorly understood, but diarrhea symptoms impede patient adherence and undermine quality of life. Objectives The purpose of this article is to review the etiology of the symptom of diarrhea in people with cancer, specifically MM. Management strategies also are discussed. Methods A comprehensive review of CINAHL®, MEDLINE®, and PubMed databases was performed using the search terms diarrhea, chemotherapy, multiple myeloma, and cancer. Research studies, guidelines, and papers from peer-reviewed publications were considered. Findings Although general guidelines from the American Society of Clinical Oncology and Oncology Nursing Society exist that suggest best practices in the management of chemotherapy-induced diarrhea, best practices to identify and manage diarrhea symptoms in patients with MM are lacking.
Tetrahedral Image-to-Mesh Conversion Approaches for Surgery Simulation and Navigation

In this paper we evaluate three different mesh generation approaches with respect to their fitness for use in a surgery simulation and navigation system. The behavior of such a system can be thought of as a trade-off between material fidelity and computation time. We focus on one critical component of this system, namely non-rigid registration, and conduct an experimental study of the selected mesh generation approaches with respect to material fidelity of the resulting meshes, shape of mesh elements, condition number of the resulting stiffness matrix, and the registration error. We concluded that meshes with very bad fidelity do not affect the accuracy drastically. On the contrary, meshes with very good fidelity hurt the speed of the mesher due to the poor quality they exhibit. We also observed that the speed of the solver is very sensitive to mesh quality rather than to fidelity. For these reasons, we think that mesh generation should first try to produce high quality meshes, possibly sacrificing fidelity.
An ω-3-enriched diet alone does not attenuate CCl4-induced hepatic fibrosis

Exposure to the halogenated hydrocarbon carbon tetrachloride (CCl4) leads to hepatic lipid peroxidation, inflammation and fibrosis. Dietary supplementation of ω-3 fatty acids has been increasingly advocated as being generally anti-inflammatory, though its effect in models of liver fibrosis is mixed. This raises the question of whether diets high in ω-3 fatty acids will result in a greater sensitivity or resistance to liver fibrosis as a result of environmental toxicants like CCl4. In this study, we fed CCl4-treated mice a high ω-3 diet (using a mix of docosahexaenoic acid and eicosapentaenoic acid ethyl esters). We also co-administered an inhibitor of soluble epoxide hydrolase, 1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU), which has been shown to boost anti-inflammatory epoxy fatty acids that are produced from both ω-3 and ω-6 dietary lipids. We showed that soluble epoxide inhibitors reduced CCl4-induced liver fibrosis. Three major results were obtained. First, the ω-3-enriched diet did not attenuate CCl4-induced liver fibrosis as judged by collagen deposition and collagen mRNA expression. Second, the ω-3-enriched diet raised hepatic tissue levels of several inflammatory lipoxygenase metabolites and prostaglandins, including PGE2. Third, treatment with TPPU in drinking water in conjunction with the ω-3-enriched diet resulted in a reduction in liver fibrosis compared to all other groups. Taken together, these results indicate that dietary ω-3 supplementation alone did not attenuate CCl4-induced liver fibrosis. Additionally, oxylipin signaling molecules may play role in the CCl4-induced liver fibrosis in the high ω-3 diet groups.
Impact of obesity on post-dural puncture headache

Abstract Introduction Previous studies have suggested an inverse relationship between obesity and development of post-dural puncture headache following spinal anesthesia. However, few have investigated the relationship between obesity and headaches after accidental dural puncture with an epidural needle. This study explored whether obesity has any association with headaches following an accidental dural puncture. Methods Records of patients who received epidural analgesia for labor and vaginal delivery between January 2011 and June 2015 were reviewed. Body mass index, American Society of Anesthesiologists Physical Status and age were analyzed. Chi-squared analysis was performed to determine the relationship between the incidence and severity of post-dural puncture headaches and body mass index. Results A total of 17497 epidurals were placed for vaginal deliveries. Of these, 164 patients met our criteria for accidental dural puncture, of whom 51.2% developed post-dural puncture headaches. Of patients who developed a post-dural puncture headache 35.7% required an epidural blood patch. Data analysis showed no significant relationship between body mass index and incidence of post-dural puncture headaches regardless of body mass index classification ( P >0.05). There was no association between body mass index and the intensity of post-dural puncture headache ( P =0.29). Conclusion Patients with a high body mass index do not appear to be protected from experiencing a post-dural puncture headache after an accidental dural puncture during placement of labor epidural analgesia. Additionally, the intensity of post-dural puncture headache does not vary with body mass index.
Generation of ortho-SF5-Benzyne and Its Diels–Alder Reactions with Furans: Synthesis of 1-SF5-Naphthalene, Its Derivatives, and 1,6(1,7)-Bis-SF5-naphthalenes

Generation of ortho-SF5-benzyne was achieved by a lithiation/elimination sequence starting from 2-fluoro-SF5-benzene. The highly reactive ortho-SF5-benzyne intermediate was trapped by furan or 2-methylfuran in situ, and the obtained stable Diels–Alder adducts were subjected to the series of further chemical transformation, which led to the formation of previously unknown 1-SF5-naphthalene and its derivatives with bromo, amino, hydroxy, and methyl substituents, including bis-SF5-substituted naphthalenes. NMR spectroscopy experiments revealed characteristic through-space coupling between the SF5-group’s equatorial fluorines and proton/carbon nuclei of −H, −CH3, and −OH substituents in the peri-position to the SF5-group of 1-SF5-naphthalenes.
Long Term Outcome after Successful Catheter Ablation of Atrial Fibrillation

Background— Pulmonary vein isolation (PVI) is increasingly used for treatment of atrial fibrillation (AF), but few reports exist regarding long-term success. We determined 5-year outcomes of PVI among patients with freedom from AF off antiarrhythmic drugs (AAD) for 1 year after PVI. Methods and Results— Consecutive patients with paroxysmal or persistent AF who underwent PVI at the University of Pennsylvania from 2000 to 2003 and were free from AF 1 year after ablation were included. Proximal isolation of PVs and non-PV triggers of AF was performed. Long-term ablation success, defined as freedom from AF off AAD after a single ablation procedure, was determined. All patients had transtelephonic monitoring at 3 to 6 months and 12 months and at least yearly contact thereafter. One hundred twenty-three patients were free of AF without AAD at 1 year. AF freedom off AAD was 85% at 3 years and 71% at 5 years, with an approximate 7% per year late recurrence rate after the first year. Patients with recurrent AF ≥5 years after index PVI were older, had larger left atrial size, more AF triggers and more likely had persistent AF. In multivariate analysis, persistent AF (odds ratio, 2.8; 95% confidence interval, 1.4 to 5.7, P =0.005) and age (odds ratio, 1.1; 95% confidence interval, 1.0 to 1.1, P =0.036) independently predicted long-term AF recurrence. Conclusions— Among patients with paroxysmal or persistent AF and AF freedom 1 year after segmental PVI, the majority (71%) remained free of AF for up to 5 years, with an approximate late recurrence rate of 7% per year. Continued vigilance for recurrent AF after PV isolation is warranted, particularly in patients with persistent AF.
Tumor Cell-Associated Tissue Factor Supports Metastatic Potential through Both NK Cell-Dependent and -Independent Mechanisms.

Multiple lines of evidence indicate that the hemostatic system contributes to cancer dissemination. Previous studies have shown that tumor cell-associated tissue factor (TF) expression is a crucial determinant of metastatic potential. Furthermore, we have shown that tumor cell-associated TF supports metastatic potential through mechanism(s) dependent on multiple circulating hemostatic system components, including prothrombin, platelets, fibrinogen and, more recently, fXIII. At least two of these circulating hemostatic factors (platelets and fibrinogen) have been shown to support metastatic potential by impeding the clearance of recently embolized tumor cells by natural killer (NK) cells. It is reasonable to hypothesize that tumor cell-associated TF expression also supports metastatic potential by a mechanism coupled to NK cell function. Here, we used C57BL/6-derived, Ras-transformed tumor cell lines expressing wildtype murine tissue factor (TFWT), a mutant TF lacking the intracytoplasmic portion (TFΔTail), or no tissue factor (TFO) to directly examine the interplay between tumor cell-associated TF and NK cell function in determining metastatic potential. Each of these cell lines was capable of robust, comparable tumor growth in wildtype C57BL/6 mice. Loss of either platelet function or fibrinogen significantly diminished the metastatic potential of TFWT cells, but this effect was entirely abrogated by the concomitant loss of NK cells. Similar results were obtained with TFΔTail cells, indicating that the cytoplasmic portion of TF is not critical to these interactions. To determine if the increase in metastatic potential conferred by tumor cell-associated TF expression is entirely linked to NK cell function, we compared the metastatic potential and early survival of TFWT and TFO cells in mice with and without NK cells. TFOcells rarely formed any visible metastatic foci in mice with intact NK cell function, while TFWT cells were aggressively metastatic. Importantly, TF expression remained a significant determinant of metastatic potential even in mice lacking NK cells. Comparisons of the early fate of TFWT and TFO cells revealed that TF expression was not a determinant of initial tumor cell localization within the lungs. Rather, TF expression supported the sustained adherence and/or survival of tumor cells. Taken together, these data indicate that one mechanism linking tumor cell-associated TF expression to metastatic potential is coupled to circulating hemostatic factors and results in impaired NK cell-mediated clearance of recently established micrometastatic foci. However, TF expression also supports metastasis by at least one additional mechanism that is independent of natural killer cell function.
Endophytic Root Colonization by Fusarium Species: Histology, Plant Interactions, and Toxicity

Fusarium species have adapted to a wide range of geographical sites, climatic conditions, ecological habitats, and host plants, and species of this polyphyletic genus have been documented to occur worldwide (Backhouse et al. 2001). In spite of the information available on the extremes in geographic distribution and climatic conditions, appropriate data to predict the center of origin(s) or the mode(s) of dispersion of this genus have not been obtained. Much of the information on distribution patterns has been determined from analyses of soil samples, a common habitat, in addition to colonization of many plant species. The diversity of plant species colonized by members of the genus Fusarium is amazing. A recent literature survey determined that Fusarium species have been isolated from plants belonging to the gymnosperms and the monocotyledonous and dicotyledonous angiosperms (Kuldau and Yates 2000). They are the primary incitants of root, stem, and ear rots in many agriculturally important crops. For example, F. verticillioides (= F. moniliforme) is capable of colonizing well over 1,000 plant species, including maize (Zea mays L.), one of the world’s most important food crops. Another species, F. oxysporum, is cosmopolitan; certain strains are usually host specific and pose a severe threat to most of the world’s supply of food crops. Furthermore, species such as F. graminearum, along with F. verticillioides and related species within the Liseola section, are notorious for the production of mycotoxins on wheat, maize, barley, rice and other cereal grains and foodstuffs (Marasas et al. 1984). Consequently, studies on the association of Fusarium species with plants are critical in order to develop control measures for this group of fungi that affects the quality and quantity of the world’s food supply.
Physical activity motivation and benefits in people with multiple sclerosis

Purpose: Multiple sclerosis is a degenerative neurological disease that affects 2.1 million people worldwide. There is no cure, but an expanding body of research supports the positive impact of phy...
Relationships among sleep quality, coping styles, and depressive symptoms among college nursing students: A multiple mediator model

Abstract Background Poor sleep quality and depressive symptoms are common among college nursing students, and may be associated with each other. However, the mechanism for this association has not been well understood. Purpose The study is to examine the potential mediating role of coping styles in the association between sleep quality and depressive symptoms among college nursing students. Methods 242 undergraduate nursing students at a public university in the northeast United States completed an online survey delivered through SurveyMonkey® with self-reports of sleep quality, coping styles, and depressive symptoms from October to November 2015. Results Multivariate linear regression models suggested that poor sleep quality was significantly associated with depressive symptoms (β = 1.00, p Conclusions In addition to sleep promotion, effective interventions to facilitate the development of appropriate coping strategies among nursing students are needed to enhance their mental health and well-being.
The Role for Associate Editors at the Journal of Chemical Education

When a manuscript is submitted to the Journal of Chemical Education, the authors will correspond primarily with an Associate Editor (AE), who has the responsibility to see the manuscript through the review process. The role for AEs in the review process is described. An AE reads the manuscript, invites reviewers, evaluates the comments and recommendations from reviewers, and makes a decision that is based on the criteria for publication in the Journal. The role for reviewers in the process and the difference between helpful reviews and less helpful reviews are also described.
Manipulation of the Geometry and Modulation of the Optical Response of Surfactant-Free Gold Nanostars: A Systematic Bottom-Up Synthesis.

Among plasmonic nanoparticles, surfactant-free branched gold nanoparticles have exhibited exceptional properties as a nanoplatform for a wide variety of applications ranging from surface-enhanced Raman scattering sensing and imaging applications to photothermal treatment and photoimmunotherapy for cancer treatments. The effectiveness and reliability of branched gold nanoparticles in biomedical applications strongly rely on the consistency and reproducibility of physical, chemical, optical, and therapeutic properties of nanoparticles, which are mainly governed by their morphological features. Herein, we present an optimized bottom-up synthesis that improves the reproducibility and homogeneity of the gold-branched nanoparticles with desired morphological features and optical properties. We identified that the order of reagent addition is crucial for improved homogeneity of the branched nature of nanoparticles that enable a high batch-to-batch reproducibility and reliability. In addition, a different combina...
Paracoccidioides brasiliensis infection mimicking recurrent Hodgkin lymphoma: a case report and review of the literature.

Paracoccidioides infection is a rare entity in the USA. This dimorphic fungus is found in Central and South America and is thought to be acquired by inhalation through the soil. We report a case of Paracoccidioides brasiliensis infection presenting as a clavicular bone lesion, peripancreatic mass, and various skin lesions. A 35-year-old man with a history significant for Hodgkin lymphoma presented with a left clavicular mass that was suspected clinically and radiologically as recurrent Hodgkin lymphoma. He was not experiencing any associated symptoms and was undergoing chemotherapy treatment for his known Hodgkin disease. On CT imaging, the mass was seen as a lytic bone lesion with an overlying soft tissue mass. This was biopsied and histologically diagnosed as a Paracoccidioides brasiliensis infection with associated necrotizing granulomatous inflammation. Also found on the CT scan was an enlarging peripancreatic mass which on endoscopic biopsy had similar histologic findings. In conclusion, this report presents a rare case of Paracoccidioides brasiliensis infection mimicking recurrent Hodgkin lymphoma.
Clinical features, treatment, prognosis, and outcome of 47 patients with pure squamous cell carcinoma of the prostate.

7Background: Pure squamous cell carcinoma of the prostate is a rare entity. Data regarding clinical features, management, and treatment outcomes are limited. As such, management of this cancer has been variable throughout the reported literature, and with limited success. Methods: A systematic review of the literature and secondary data analysis was performed to characterize clinical features, management, and survival outcomes. Results: In total, 47 cases of histologically-confirmed pure squamous cell carcinoma of the prostate were included in analysis. Pure squamous cell carcinoma of the prostate is a disease of older males with mean age at diagnosis of 68.5 years (range 42-85). Urinary obstruction was reported as a presenting symptom in 60% of cases. PSA was usually normal with a mean value of 1.6 (n = 11). The disease was metastatic at diagnosis in 32% of patients among cases that stage was reported (n = 31). The most common sites ( > 30%) of distant metastases are bone and lymph nodes. Metastasis to l...
The Emergence of Local Government Policy Leadership: A Roaring Torch or a Flickering Flame?

State and local governments traditionally exerted leadership in policy areas that directly affected their communities and citizens. The leadership of cities, however, has expanded into a number of ...
Functional-guided radiotherapy using knowledge-based planning

Abstract Background and purpose There are two significant challenges when implementing functional-guided radiotherapy using 4DCT-ventilation imaging: (1) lack of knowledge of realistic patient specific dosimetric goals for functional lung and (2) ensuring consistent plan quality across multiple planners. Knowledge-based planning (KBP) is positioned to address both concerns. Material and methods A KBP model was created from 30 previously planned functional-guided lung patients. Standard organs at risk (OAR) in lung radiotherapy and a ventilation contour delineating areas of high ventilation were included. Model validation compared dose-metrics to standard OARs and functional dose-metrics from 20 independent cases that were planned with and without KBP. Results A significant improvement was observed for KBP optimized plans in V20Gy and mean dose to functional lung (p = 0.005 and 0.001, respectively), V20Gy and mean dose to total lung minus GTV (p = 0.002 and 0.01, respectively), and mean doses to esophagus (p = 0.005). Conclusion The current work developed a KBP model for functional-guided radiotherapy. Modest, but statistically significant, improvements were observed in functional lung and total lung doses.
75 Symptom management at the end of life: an evaluation of documented response post-administration of anticipatory medications in a district general hospital

Background The standard of practice for end of life care in the UK is to use anticipatory medications for symptom control. Given this it is important for the benefits or side effects of the medication to be identified so they can be adjusted to meet the patient‘s needs. Aim To assess how frequently the response to anticipatory medications was documented by nursing staff, in both general wards and specialist palliative care beds at a district general hospital. Methods A retrospective audit was conducted at a district general hospital in the UK. All palliative care referrals during October 2016 were audited for evidence of anticipatory medication use and whether there was any nursing documentation of its effectiveness. This was also done for all patients admitted to the newly-established specialist palliative care beds at the same hospital over a three month period in 2017. Results 102 patients were referred to palliative care in October 2016, of which 50 had anticipatory medications given. Of 103 anticipatory medications administered 18.4% (19 out of 103 medications) had documentation of the effect on symptoms. There were 24 patients admitted to the specialist palliative care beds for end of life care over a 6 week perios, of which 21 had anticipatory medications administered. Of these patients 31.6% (18 out of 57 medications) had documentation of the effect on the patient‘s symptoms. Conclusions This study demonstrates that the effect of anticipatory medications is poorly recorded in the nursing notes on wards in a district general hospital. However, there is improvement when the patient is managed in a specialist palliative care bed on a general hospital ward. Further training is required to improve this documentation and allow accurate monitoring of symptoms. The designated specialist palliative care bed model may provide an opportunity for training of nurses across the hospital.
Does Utilitarianism Favor Economic Equality

It has often been claimed that, other things being equal, utilitarianism favors egalitarian economic arrangements. My criticism of this claim will be internal, and I will therefore not challenge the approach and assumptions underlying it. In particular: Since the claim relies on the assumption that all persons have diminishing marginal utility for income, I will grant this assumption. Since the phrase “other things being equal” is meant to abstract from any economic benefits achievable through incentives and also from any special problems raised by diseases and handicaps, I will leave all such matters aside. Since the claim, and the very idea of utilitarianism, presuppose that utilities are interpersonally comparable, I will grant this assumption as well, for the sake of the argument.
Numerical analysis of the effect of T-tubule location on calcium transient in ventricular myocytes.

Intracellular calcium (Ca2+) signaling in cardiac myocytes is vital for proper functioning of the heart. Understanding the intracellular Ca2+ dynamics would give an insight into the functions of normal and diseased hearts. In the current study, spatiotemporal Ca2+ dynamics is investigated in ventricular myocytes by considering Ca2+ release and re-uptake via sarcolemma and transverse tubules (T-tubules), Ca2+ diffusion and buffering in the cytosol, and the blockade of Ca2+ activities associated with the sarcoplasmic reticulum. This study is carried out using a three dimensional (3D) geometric model of a branch of T-tubule extracted from the electron microscopy (EM) images of a partial ventricular myocyte. Mathematical modeling is done by using a system of partial differential equations involving Ca2+ , buffers, and membrane channels. Numerical simulation results suggest that a lack of T-tubule structure at the vicinity of the cell surface could increase the peak time of Ca2+ concentration in myocytes. The results also show that T-tubules and mobile buffers play an important role in the regulation of Ca2+ transient in ventricular myocytes.
Introduction to Part: Research Use at the School and District Level

This chapter presents an overview of the chapters in Part I focused on research use at the local level. These chapters each emphasize interactive processes associated with research use in local educational systems. They underscore the fact that multiple actors at different levels of systems and from outside the system are implicated in research use. The chapters offer different perspectives on research use and focus on different kinds of actors. Taken together, they draw attention to the need for future studies that attend to the challenges of learning to use research to change leadership practice, the social structure that shapes flows of research within local systems, and the political dimensions of research use.
Sand Transport Paths in the Mojave Desert, Southwestern United States

Remote sensing and field evidence are used to describe sand deposits found in associated pathways of emplacement in the eastern Mojave Desert. Two separate pathways are identified here: one extending eastward from the Bristol Playa through the Cadiz and Danby Playas and Rice Valley to the Colorado River, and a second parallel path extending eastward from Dale Playa through the Palen and Ford Playas to the Mule Mountains near the Colorado River. The preferential location of sand ramps on the west slopes of mountains along each path suggests that the eastward moving, wind-driven sand was not confined by topographic divides between separate drainage basins around the individual playas and valleys. Sediment analysis of selected samples shows that there are discreet associations of sand characteristics along the sand pathways, with an inferred similarity between the stabilized (vegetated) sands in Rice Valley, west of the Colorado River, and stabilized sand dunes on Cactus Plain and La Posa Plain in Arizona, east of the Colorado River. Sand transport along the paths appears to have been episodic, based on multiple paleosols present in several dissected sand ramps. Future testing of the sand transport path hypothesis will require additional sediment analyses, spectral studies of remote sensing data, and obtaining dates for selected soil horizons along the sand paths.
Deviance and Gender

The same general models that were estimated for males and females during adolescence are estimated to examine the moderating influence of gender in explaining young adult deviance.
A Terror Management Perspective on the Psychology of Control

Although humans share many features with other animals, the system through which they control their behavior is radically different from that found in any other species. Rather than relying entirely on genetically endowed, fixed response patterns and simple learned responses to environmental stimuli, humans exert a measure of control over their own behavior through a complex system of meanings and values that evolved over the millennia to provide a measure of flexibility and adaptability in human affairs that far surpasses that found in any other life-forms. Although the human system of self-regulation is constructed upon the simpler systems by which the behavior of other species is regulated, only humans use a linguistically based concept of self as the focal point for cognitive, behavioral,and affective control—which is effected and affected by focusing attention on this symbolic self. Because a substantial proportion of human activity is driven by this abstract linguistic self, we transcend the purely physical realm in which all other species reside and enter a different plane of subjective existence.
Variation in academic preparation and progression of nurses across the continuum of care.

Abstract Background Changing health care needs are driving new models of care that emphasize care coordination, health promotion, and disease management by registered nurses (RNs). A skill-mix favoring professional (baccalaureate or above) over technical (less than baccalaureate) education is promoted by national initiatives. Purpose To examine the academic preparation and progression of general practice RNs in practice settings across the care continuum. Method Secondary analyses of data from the Texas Board of Nurses RN Licensure databases in 2008 and 2014. Findings Overall the professional skill-mix for general practice RNs improved from 47.1% to 50.2%. Disparities were identified in home health (31.6%), long-term care (27.8%) and nonmetropolitan areas (31.7%). Role change was the strongest correlate of academic progression. Discussion Non-hospital and rural practice settings may be vulnerable to the effects of an undereducated RN workforce. More effective reimbursement policies and employer incentives are needed to drive academic progression and address disparities across practice settings.
Seasonality of fish recruitment in a pulsed floodplain ecosystem: Estimation and hydrological controls

Hydrological variation is believed to be the main density-independent factor that controls fish recruitment in floodplain ecosystems. However, our ability to fully understand these controls is greatly impeded by the size-selective nature of sampling gear. To illustrate the benefits of estimating the effects of size-selective bias on population parameters, we used a cohort analysis to reconstruct a 20-year time series of larval/neonate abundance for five species in the Order Cyprinodontiformes along a hydrological gradient in the Florida Everglades. We applied generalized linear models to estimate recruit density and analyze size-selectivity for our sampling gear. The adjusted data resulted in a 7 to 40-fold increase in estimated recruit density, which varied seasonally at regional and local spatial scales and was greatest at the end of the wet season (October, December) for most species; no consistent seasonality in recruitment of any species was apparent in the raw data. Using the adjusted data, we detected a positive relationship between recruit density and recovery time following marsh drying events at short and intermediate-hydroperiod sites for all species. However, depth was the major hydrological driver of recruitment at long-hydroperiod sites. Within sites, we observed interspecific variation in species responses to changes in annual hydroperiod. We suggest that fisheries models can be applied to data from any meshed sampling gear to improve abundance estimates and reveal seasonal recruitment dynamics. Our use of such models revealed seasonal recruitment dynamics that were previously undetected, with implications for planning of restoration and management of the Everglades.
A 16 Year Old with Hair Loss

A 16-year-old girl presents to a pediatrician with significant distress surrounding acute hair loss. She says for the past few weeks she has been losing “clumps” of hair on her pillow, in her shower, and in her hair brush. She typically washes her hair every day, but recently has decreased to once weekly out of a desire to mitigate the loss. She is only combing with a wide-toothed comb, and does not use any styling products. She is very anxious and upset about her loss of hair. She is accompanied by her mother and two younger sisters.
Schizophrenia Case Study: Residual Thought Disorder versus Emerging Dementia

This chapter describes the challenging differential diagnosis of cognitive impairment in a patient with a severe psychiatric disorder. An older adult with a long history of a schizophrenia-spectrum disorder presented with exacerbation of psychotic symptoms, aggression, and cognitive concerns. The patient and his psychiatrist wondered about the source of the cognitive deficits and how this would affect his treatment options and prognosis. In addition to a long-standing serious mental illness, this patient had a number of possible medical conditions associated with cognitive decline and was also taking medications that affect cognition. The patient was referred for neuropsychological assessment. The neuropsychologist worked collaboratively with the psychiatrist and patient to discern whether the cognitive changes were related to schizophrenia, incipient dementia, or medication effects. Input from neuropsychology aided in treatment planning.
Sterically Controlled Alkylation of Arenes Through Iridium‐Catalyzed C—H Borylation.

This publication describes the site-selective alkylation, allylation, and benzylation of arenes via in-situ-generated aryl pinacol boronates.
Crystal structures and hydrogen-bonding analysis of a series of solvated ammonium salts of molybdenum(II) chloride clusters

Charge-assisted hydrogen bonding plays a significant role in the crystal structures of solvates of ionic com­pounds, especially when the cation or cations are primary ammonium salts. We report the crystal structures of four ammonium salts of molybdenum halide cluster solvates where we observe significant hydrogen bonding between the solvent molecules and cations. The crystal structures of bis­(anilinium) octa-μ3-chlorido-hexa­chlorido-octa­hedro-hexa­molybdate N,N-di­­methyl­formamide tetra­solvate, (C6H8N)2[Mo6Cl8Cl6]·4C3H7NO, (I), p-phenyl­enedi­ammonium octa-μ3-chlorido-hexa­chlorido-octa­hedro-hexa­mol­yb­date N,N-di­methyl­formamide hexa­solvate, (C6H10N2)[Mo6Cl8Cl6]·6C3H7NO, (II), N,N′-(1,4-phenyl­ene)bis­(propan-2-iminium) octa-μ3-chlorido-hexa­chlo­rido-octa­hedro-hexa­molybdate acetone tris­olvate, (C12H18N2)[Mo6Cl8Cl6]·3C3H6O, (III), and 1,1′-dimethyl-4,4′-bipyridinium octa-μ3-chlo­rido-hexa­chlorido-octa­hedro-hexa­molybdate N,N-di­methyl­formamide tetra­solvate, (C12H14N2)[Mo6Cl8Cl6]·4C3H7NO, (IV), are reported and described. In (I), the anilinium cations and N,N-di­methyl­formamide (DMF) solvent mol­ecules form a cyclic R42(8) hydrogen-bonded motif centered on a crystallographic inversion center with an additional DMF mol­ecule forming a D(2) inter­action. The p-phenyl­enedi­ammonium cation in (II) forms three D(2) inter­actions between the three N—H bonds and three independent N,N-di­methyl­formamide mol­ecules. The dication in (III) is a protonated Schiff base solvated by acetone mol­ecules. Compound (IV) contains a methyl viologen dication with N,N-di­methyl­formamide mol­ecules forming close contacts with both aromatic and methyl H atoms.
Aeroelastic model tests to study tall building vibration in boundary-layer and tornado winds

Abstract A three-degree-of-freedom aeroelastic model of the standard CAARC Tall Building with a rectangular cross section was tested in both atmospheric-boundary-layer (ABL) wind tunnel and tornado simulator to assess its susceptibility to wind-induced vibration in straight-line wind and tornado wind and compare the two responses. Time histories of acceleration at roof-height and mid-height of the model were measured at different wind speeds. The normalized response of the tall building model was obtained with respect to reduced velocities at critical angles of attack for the boundary-layer wind and at critical locations and orientations with respect to the tornado path. The aerodynamic damping of the tall building was identified from the measurements and validated with other tests; furthermore, the results were analyzed in both time-domain and frequency-domain to reveal the response characteristics. A comparison of the vibration response shows that the characteristics of the tornado-induced excitation are different and its magnitudes are much more severe from those of the conventional straight-line wind. The results obtained from this study can be used to validate both wind-tunnel and numerical methodologies used for assessing the wind-induced vibration of a tall building and will eventually help to develop guidelines to reduce the wind-induced damage or occupant discomfort as a result of excessive vibration.
Electronics-Free Logic Circuits for Localized Feedback Control of Multi-Actuator Soft Robots

The vision of creating entirely-soft robots capable of performing complex tasks will be accomplished only when the controllers required for autonomous operation can be fully implemented using soft components. Despite recent advances in compliant fluidic circuitry for mechanical signal processing, the applicability of this technology for soft robot control has been limited by complicated fabrication and tuning processes, and also the need for external signals such as clocks and digital references. We propose a method to develop pneumatic soft robots in which coordinated interactions between multiple actuators are performed using controllers implemented on components distributively embedded in the soft structures of the system. In this approach, the notions of binary and multi-valued actuator logic states are introduced. In this way, the physical local dynamical couplings between the analog states of the actuators, established using soft valves of a new type, can be thought of as logic-gate-based mappings acting on discretized representations of the actuator states. Consequently, techniques for digital logic design can be applied to derive the architectures of the localized mechanical couplings that intelligently coordinate the oscillation patterns of the actuator responses. For the purposes of controller tuning, the soft valves are conceived so that their main physical parameters can be adjusted from the exterior of the robot through simple geometrical changes of the corresponding structural elements. To demonstrate the proposed approach, we present the development of a six-state locomoting soft robot.
Quality management theory development via meta-analysis

Abstract Quality management (QM) research has frequently focused on investigating the QM system, while a collective consideration of the effects of individual QM practices on organizational performance and performance dimensions remains an under-investigated area of research. The current research provides insights for expanding quality management theory using evidence from a meta-analysis that examines the correlations presented in prior empirical studies. Specifically, this study investigates whether QM practices influence aggregate organizational performance and how individual QM practices influence different performance dimensions. Furthermore, this study investigates whether moderators exist among the relationships between QM and performance. This meta-analysis examined a sample of 28 empirical studies spanning a twenty-year period from 1995 to 2015. The results show that most individual QM practices have a positive impact on aggregate organizational performance and performance dimensions including financial performance, operational performance, customer service, and product quality. The results also reveal that moderators exist among relationships between most pairs of QM practices and performance. In particular, the results suggest a high level of importance is associated with management leadership and supplier quality management compared to other QM practices, as evidenced by their positive relationships with both aggregate organizational performance and the four performance dimensions. In addition, no moderating effects changed the relationships. This research contributes to the QM literature by providing a systematic understanding that addresses more complexity than previous research about the relationships between QM practices and organizational performance. This research also contributes to quality management theory development given the current state of information technology (IT). These findings suggest implications for managers interested in the effect of QM practices on performance.
Wearable and Flexible Ozone Generating System for Treatment of Infected Dermal Wounds

Wound-associated infections are a significant and rising health concern throughout the world owing to aging population, prevalence of diabetes, and obesity. In addition, the rapid increase of life-threatening antibiotic resistant infections has resulted in challenging wound complications with limited choices of effective therapeutics. Recently, topical ozone therapy has shown to be a promising alternative approach for treatment of non-healing and infected wounds by providing strong antibacterial properties while stimulating the local tissue repair and regeneration. However, utilization of ozone as a treatment for infected wounds has been challenging thus far due to the need for large equipment usable only in contained, clinical settings. This work reports on the development of a portable topical ozone therapy system comprised of a flexible and disposable semipermeable dressing connected to a portable and reusable ozone-generating unit via a flexible tube. The dressing consists of a multilayered structure with gradient porosities to achieve uniform ozone distribution. The effective bactericidal properties of the ozone delivery platform were confirmed with two of the most commonly pathogenic bacteria found in wound infections, Pseudomonas aeruginosa and Staphylococcus epidermidis. Furthermore, cytotoxicity tests with human fibroblasts cells indicated no adverse effects on human cells.
Characterization of the Piezoelectric Response of Aluminum Nitride Grown by dc Magnetron Sputtering for Applications in Thin-Film Resonators

Aluminum nitride is a promising material for use in thin-film bulk acoustic wave resonators for applications in RF bandpass filters. This paper discusses the requirements needed for a dc magnetron sputtering system to grow piezoelectrically active films with x-ray diffraction rocking curves of 3.3° on silicon substrates, 5° on aluminum substrates and oxygen concentrations of l at.%. For applications in integrated resonators, a materials characterization is insufficient in predicting the subsequent device performance. A simple acoustic device structure which allows a quick measurement of the device performance is used to extract maximum effective coupling coefficients keff 2 of 0.009% at 3.4GHz and 0.002% at 2.4GHz for two different films with rocking curves of 5.7° and 9.0° respectively. This parameter extraction technique may be used to make relative comparisons between films grown under different deposition conditions.
Oil-coated bubbles in particle suspensions, capillary foams, and related opportunities in colloidal multiphase systems

Abstract The interaction of solid particles with fluid interfaces in colloidal multiphase systems can lead to a wide range of fascinating and sometimes useful phenomena. Most of the research in this area has focused on ternary systems with two immiscible fluids and one particle species. After a brief review of some common characteristics, this article discusses recent insights and future opportunities regarding systems that confront particles with multiple types of fluid interfaces, focusing in particular on the interaction of particles with oil-coated bubbles in aqueous media. Relevant examples include the particle-assisted reconfiguration of bubble–droplet morphologies, the separation of hydrophilic particles from aqueous slurries by oily bubble flotation, and the formation of capillary foams, a promising new class of foam materials.
How telehealth care exploded due to COVID: What nurse researchers need to know.

1.1. The COVID‐19 pandemic compelled a surge of telemedicine activity to provide social distancing between health care providers and their patients, buoyed by a flurry of simultaneous federal and state telehealth policy changes to accommodate as many patients as possible. These policy adaptations included an increased number of telehealth services that could be reimbursed by Medicare, many state Medicaid plans, and even private insurers. The policy changes also relaxed Health Insurance Portability and Accountability Act (HIPAA) requirements for the technology platforms used, allowed for controlled medications to be prescribed remotely without first having an in‐person examination, and made it easier for many types of health care professionals to practice across state lines under their current home‐state licenses. These rapid policy updates were necessary, as some studies have indicated that up to an unprecedented 80% of all outpatient appointments were being conducted via telehealth during the peak periods of late March through May. Moreover, health systems, mental health centers, hospitals, and other health care organizations had to rapidly implement telehealth systems and protocols to meet the demand. As COVID‐19 induced telehealth activity enters its 10th month, a few key questions have emerged. First, what have been the effects of this unprecedented pandemic and related policy changes on telehealth volume? Also, how has policy evolved and what policy accommodations will continue post‐COVID? Will providers continue to leverage telehealth after the public health emergency ends? This short editorial opinions page provides some initial thoughts on these important questions.
Syntactic complexity across academic research article part-genres: A cross-disciplinary perspective

Abstract This study examined eight measures of syntactic complexity across published research article part-genres (Introduction, Methods, Results, and Discussion) and three social science disciplines (Applied Linguistics, Psychology, and Economics). The corpus of 240 complete texts was analyzed using a modified version of the Syntactic Complexity Analyzer (SCA), and the measures were compared across disciplinary and part-genre variables using a Two-way MANOVA and a series of follow up MANOVA and ANOVA tests. The findings highlight a significant large effect of both discipline and part-genre on all eight syntactic complexity indices, as well as a significant but small effect size for the interaction of move and discipline on the complexity measures. Important disciplinary and part-genre based differences in the use of syntactically complex structures are discussed, as are the implications of these findings on EAP writing research and pedagogy.
New reproductive biothechnologies that affect the dairy industry

The emerging biotechnologies will have a revolutionary effect upon domestic animal breeding. The current state of development for in vitro maturation of oocytes, their in vitro fertilization and “cloning” suggests that they will have a major impact on animal agriculture within 5-10 years.