cssi/SciSciGPT-SciSciNet huggingface dataset:
Book Review: Evangelical versus Liturgical? Defying a Dichotomy

Evangelical versus Liturgical? Defying a Dichotomy. By Melanie C. Ross. Grand Rapids, Mich.: Eerdmans Publishing, 2014. 148 pp. $17.00 (paper).For Christians at a historic inflection point, any attempt to mitigate division between "evangelical" and "liturgical" forms of Christianity deserves consideration. Melanie Ross's book, if not seamless, poses good questions about what those two traditions of practice and theology hold in common, and where they may differ in important ways.One might reasonably expect that defiance of a dichotomy would work from both sides of it; however, while the book does commend what both traditions have to offer each other, its emphasis is a defense of evangelical Christianity from putative misconstruals by liturgical theologians. Ross means to challenge liturgical studies to "be both more historical and more theological in its assessment of evangelical worship, which in turn will require a rethinking of the evangelical-liturgical relationship" (p. 6). In chapter 1 she provides an informative history of the liturgical ordo of evangelical worship with the intention of showing that evangelicals have moved beyond that "frontier ordo" that runs through Charles Finney into the "seeker services" of the megachurches, now on the wane. Along the way, Ross nicely captures some of the cross-denominational and pragmatic characteristics of evangelical worship. Later, two cases (chapters 2 and 5) mean to thicken the readers appreciation for exemplary evangelical liturgical practices today. Even if the case descriptions do not entirely persuade that something substantively different than the frontier ordo is going on there, Ross does successfully show that mission outcomes liturgical theologians hope will flow from robust liturgy are impressively alive in those evangelical churches and clearly connected, in their practitioners' reflections, with their worship life.Chapter 3 offers an account of the relationship between scripture and liturgy. Placing Aidan Kavanagh and Louis-Marie Chauvet in dialogue with John Webster, Ross shows common concern among evangelical and liturgical theologians that the Bible not be interpreted naively, while protecting the evangelical claim that the Bibles meaning is not an ecclesial-liturgical creation but a discovery empowered by the Spirit. This point is well articulated, even if one thinks that the difference between Roman Catholic and Protestant ecclesial cultures better explains the differences at work in her dialogue partners than the evangelical-liturgical dichotomy. Placing Gordon Lathrop in dialogue with Kevin Vanhoozer on the shared recognition of the metaphoric, symbolic, and mythic content of biblical material, Ross defends evangelical attention to its propositional and confessional content. One who knows Lathrop's work may be inclined to say that his work takes account precisely of the interplay of all biblical genres, including the propositional. …
Prospective Study of Adenosine on Atrioventricular Nodal Conduction in Pediatric and Young Adult Patients After Heart Transplantation.

Background —Supraventricular tachycardia (SVT) is common after heart transplant. Adenosine, the standard therapy for treating SVT in children and adults without transplant, is relatively contraindicated post-transplant due to a presumed risk of prolonged atrioventricular (AV) block in denervated hearts. This study tested whether adenosine caused prolonged asystole after transplant and if it was effective in blocking AV nodal conduction in these patients. Methods —This was a single center prospective clinical study including healthy heart transplant recipients ages 6 months - 25 years presenting for routine cardiac catheterization during 2015 - 2016. After catheterization, a transvenous pacing catheter was placed and adenosine was given following a dose escalation protocol until AV block was achieved. The incidence of clinically significant asystole (≥ 12 seconds following adenosine) was quantified. The effects of patient characteristics on adenosine dose required to produce AV block and duration of effect were also measured. Results —Eighty patients completed adenosine testing. No patient (0%; 95% CI 0-3%) required rescue ventricular pacing. AV block was observed in 77 patients (96%; 95% CI 89-99%). The median longest AV block was 1.9 seconds (IQR 1.4-3.2) with the mean duration of adenosine effect 4.3 seconds (±2.0). No patient characteristic significantly predicted adenosine dose to produce AV block or duration of effect. Results were similar across patient weight categories. Conclusions —Adenosine induces AV block in healthy pediatric and young adult heart transplant recipients with minimal risk when using low initial doses (25mcg/kg, or 1.5mg if ≥ 60kg) and gradually escalating therapy. Clinical Trial Registration —URL: https://clinicaltrials.gov Unique Identifier: [NCT02462941][1] [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT02462941&atom=%2Fcirculationaha%2Fearly%2F2017%2F04%2F27%2FCIRCULATIONAHA.117.028087.atom
Bite me! ABC’s Shark Tank as a path to entrepreneurship

Business pitch competitions provide early-stage finance and mentoring for entrepreneurs. In this paper, we analyze data from the most public, high-stakes pitch competition in the USA: ABC’s Shark Tank. We construct a dataset comprising all entrepreneurs/firms that have aired between August 2009 and May 2016. Our findings: (1) funding on the show seems to relax an internal financial constraint, rather than signal the quality of the venture to potential outside investors; (2) to the extent that the latter is occurring, there is plausible evidence that the signaling effect works in an unexpected direction for women entrepreneurs—it may crowd out attention from potential investors; (3) while it is fairly clear that this pitch competition is associated with longer-run existence of firms, it has no significant impacts on innovation; (4) there are no consistent differential impacts on racial/ethnic minorities. These findings complement the literature on the impact of pitch competitions and (early) access to finance.
Compatibility of Nitric Oxide Release with Implantable Enzymatic Glucose Sensors Based on Osmium (III/II) Mediated Electrochemistry

The compatibility of nitric oxide (NO) release coatings with implantable enzymatic glucose sensors based on osmium (III/II) mediated electrochemical detection is examined for the first time. NO-releasing osmium-mediated glucose sensors are prepared using a S-nitrosothiol impregnated outer tubing and are tested in vitro in both phosphate buffer (pH 7.4) and within whole porcine blood. It is demonstrated that after 3 days of continuous NO release at or above physiological levels, there are no negative effects on the osmium mediated elec-trochemical currents. Indeed, such sensors maintain their func-tionality, sensitivity, and accuracy for detecting glucose levels in blood. The results suggest that improved performance of both intravascular and, potentially, subcutaneous Os(III/II) mediated glucose sensors may be realized by taking advantage of NO’s well known anti-clotting, anti-inflammatory and an-timicrobial properties.
Coffee Consumption and Prevention of Cirrhosis: In Support of the Caffeine Hypothesis

Coffee is acknowledged as the most widely used drug worldwide. Coffee is also a foodstuff, so its use is often used to satisfy dietary urges. When used as a drug, coffee is normally consumed as a stimulant rather than to treat or prevent particular diseases. Recently, coffee consumption has been inversely related to progression of liver fibrosis to cirrhosis and even hepatocellular carcinoma. Experiments in cellular and animal models have provided biological plausibility for coffee as an antifibrotic agent in the liver. A recent article examined one of the key questions regarding the antifibrotic role of coffee-specifically what is the primary antifibrotic agent in coffee? This article briefly reviews the relevant issues with regard to coffee as an antifibrotic agent for patients with chronic liver disease.
Perceptions of Quality in Interventional Oncology.

Abstract Purpose To inductively characterize perceptions of quality in interventional oncology (IO) based on values and experiences of patients and referring providers. Materials and Methods Brief ethnographic interviews were completed with referring providers and patients before and after a variety of liver-directed procedures about their experiences, concerns, and perceptions of IO services at a single institution. Constructivist grounded theory was used to systematically analyze interview transcripts for themes until thematic saturation was achieved. All transcripts were analyzed by a reviewer with 3-years of experience performing such analyses, and 50% were randomly selected to be coded by 2 additional blinded reviewers. Interreviewer agreement was assessed via Cohen κ. Results Interviews with 22 patients (mean age, 65 y ± 13; 9 women) and 12 providers (mean age, 54 y ± 9; 6 women) were required to reach and confirm thematic saturation. Interreviewer agreement for interview themes was excellent (κ = 0.78; P Conclusions An inductive qualitative approach effectively characterized specific aspects of perceptions of high-quality IO care among patients and referring providers.
Conditional Conservatism and Labor Investment Efficiency

Abstract Prior literature documents that asymmetric timely recognition of losses versus gains (also known as conditional conservatism) can induce management to make more efficient investment decisions by mitigating information asymmetry between management and investors and providing early signals about the profitability of projects that are undertaken. In this paper, we investigate the impact of conservatism on an important investment decision that has been overlooked, namely, investment in labor. We find that conservatism is negatively associated with labor investment inefficiency; more specifically, conservatism reduces inefficient investment practices on the labor market, including over-hiring, under-firing, under-hiring, and over-firing. Our results hold after controlling for managerial ability, corporate governance, and other investments.
A brief history of our understandings on underwater noise impacts to marine life and the evolution of its regulatory process in the United States

It has been long understood that elevated noise is detrimental to signal detection by the anti-submarine warfare community. However, it was not until the early 1970s that similar concerns were raised regarding marine life that utilize sound for various life functions. The 1980s saw some of the first studies on effects of noise from offshore oil and gas exploration and development on marine mammals in Arctic waters. Low-frequency sources for ocean thermometry research and submarine detection over ocean basins brought additional concerns in the early 1990s on potential impacts on marine mammals from intense sources. Around late 1990s, several ad-hoc noise levels were adopted as acoustic impact thresholds of marine mammals by regulatory agencies in the U.S. Several cetacean mass stranding events that were coincidental with the mid-frequency military sonar operations and the increased awareness of ocean noise pollution accelerated research in this field in the 21st Century. Numerous studies on hearing sensiti...
Digital Media and the Transformation of Space

This chapter analyzes how digital media have changed our perception and use of physical spaces as well as created new forms of space – virtual space. The discussion is placed in an historical context of the relationships between media and space, beginning with the telegraph, telephone, radio, phonograph recordings and television. Digital media such as mobile phones and broadband along with applications such as mobile maps, location-based services and virtual reality games have transformed our sense of space and the ways we use it. Physical spaces have not disappeared nor have social norms that influence behavior in specific spaces. However, the changes that have taken place are significant and hold implications for businesses, politics, entertainment and social life.
Introduction — Why Amateur Astronomy?

I have always felt that most people are fascinated by what is generally termed “Space.” As an 11-year-old I, along with everyone else on the planet, watched in awe as Armstrong and Aldrin landed on the Moon. The human race has never been more transfixed. Who hasn’t gazed up at the night sky and asked “Why are we here?” or “Is there anybody else out there?” Science fiction like Star Trek and Star Wars has always attracted millions of viewers and Sci-Fi comedy like Douglas Adams’ The Hitchhikers Guide to the Galaxy has always been popular.
The Intersection Between Cancer and Caregiver Survivorship

A plethora of literature concerning cancer survivorship exists including research concerning quality of life through the cancer trajectory (e.g., diagnosis to the end of life). A separate but related literature exists for cancer caregivers. However, the intersection between patient and caregiver survivorship exists in reality, but the link between the two is nonexistent in the research literature. The support from the medical team who cares for the patient often abruptly ends when treatment is discontinued and for the minority of patients diagnosed with cancer who are referred to hospice, bereavement support is offered but rarely utilized for the caregivers after the loss of their loved ones (Casarett and Quill, Ann Intern Med 146:443–449, 2007; Reid et al. Int J Palliat Nurs 12:430–437, 2006). The goal of this chapter was to begin to bring these two areas of research together and bridge this critical intersection in the patients’ and caregivers’ lives.
Examining the Relationship Between Preservice Elementary Teachers’ Attitudes Toward Mathematics and Professional Noticing Capacities

The goal of this study was to examine the changes in preservice elementary teachers’ attitudes toward mathematics in connection with their participation in a module aimed at developing professional noticing capacities. This module, implemented in 11 mathematics methods courses at five institutions, involved practice with three interrelated components of professional noticing—attending, interpreting, and deciding. Pre- and post-assessments of participants’ mathematical attitudes and professional noticing capacities were administered to measure change in these areas. Professional noticing measures were modeled from a similar study by Jacobs et al. (Journal for Research in Mathematics Education 41: 169–202, 2010). The Attitudes Toward Mathematics Inventory (Tapia and Marsh, Academic Exchange Quarterly 8: 16–21, 2004) was used to measure change in attitudes during the pre- and post-administrations. Participants demonstrated significant growth in professional noticing capabilities and significant growth on three of four factors of the Attitudes Toward Mathematics Inventory; however, there was no significant correlation between the changes on the respective measures.
Public Health Implications of Very Preterm Birth.

With advanced perinatal care and technology, survival among infants born very preterm (<32 weeks gestation) has improved dramatically over the last several decades. However, adverse medical and neurodevelopmental outcomes for those born very preterm remains high, particularly at the lowest gestational ages. Public health plays a critical role in providing data to assess population-based risks associated with very preterm birth, addressing disparities, and identifying opportunities for prevention, including improving the health of reproductive-age women, before, during, and after pregnancy.
Patient-Reported Outcomes Before and After Primary and Revision Total Ankle Arthroplasty.

Background:Studies examining the clinical outcomes of revision total ankle arthroplasty (TAA) are sparse. Revision TAA surgery has become more common with availability of revision implants and refi...
Use of FDA's Sentinel System to Quantify Seizure Risk Immediately Following New Ranolazine Exposure.

Neurological complications including seizures have been reported with ranolazine. We sought to quantify the risk of seizure-related hospitalizations or emergency department events following ranolazine exposure in the Sentinel System (2006–2015). Eligibility criteria were new use of ranolazine after 183 days washout period and absence of seizure diagnoses, anti-epileptic drugs, or seizure-related disorders during the baseline period. Among 52,155 ranolazine users, we identified 28 seizures in the 1–32 days after new ranolazine dispensing: 12 occurring in days 1–10 (high-risk window), 11 in days 11–20 (moderate-risk window) and 5 in the control window (days 21–32). Assuming an equal likelihood of seizure events across the 32-day observation window, we estimate an attributable risk of 0.9 excess cases per 10,000 exposed users. Using a self-controlled risk interval design with exact logistic regression, seizures were elevated in the high-risk window (relative risk [RR] 2.88 (95% confidence interval [CI] 1.01–8.33) compared with the control window. No significant increased risk was observed in the moderate window. Half of the seizure cases had a diagnosis of renal disease, although seizure risk was not significant (RR 3.20 [CI 0.82–14.01]). A majority of patients in both risk windows were 75 years or older. Our study suggests risk among younger ranolazine patients is rare. Given the imprecision of the risk estimates, we interpret the elevated seizure risk following ranolazine exposure with caution. Further analysis in a larger elderly population is warranted.
The Carboxy-Terminus, a Key Regulator of Protein Function

All proteins end with a carboxyl terminus that has unique biophysical properties and is often disordered. Although there are examples of important C-termini functions, a more global role for the C-terminus is not yet established. In this review, we summarize research on C-termini, a unique region in proteins that cells exploit. Alternative splicing and proteolysis increase the diversity of proteins and peptides in cells with unique C-termini. The C-termini of proteins contain minimotifs, short peptides with an encoded function generally characterized as binding, posttranslational modifications, and trafficking. Many of these activities are specific to minimotifs on the C-terminus. Approximately 13% of C-termini in the human proteome have a known minimotif, and the majority, if not all of the remaining termini have conserved motifs inferring a function that remains to be discovered. C-termini, their predictions, and their functions are collated in the C-terminome, Proteus, and Terminus Oriented Protein Function INferred Database (TopFIND) database/web systems. Many C-termini are well conserved, and some have a known role in health and disease. We envision that this summary of C-termini will guide future investigation of their biochemical and physiological significance.
QTest 2.1: Quantitative testing of theories of binary choice using Bayesian inference

Abstract This stand-alone tutorial gives an introduction to the QTest 2.1 public domain software package for the specification and statistical analysis of certain order-constrained probabilistic choice models. Like its predecessors, QTest 2.1 allows a user to specify a variety of probabilistic models of binary responses and to carry out state-of-the-art frequentist order-constrained hypothesis tests within a Graphical User Interface (GUI). QTest 2.1 automatizes the mathematical characterization of so-called “random preference models”, adds some parallel computing capabilities, and, most importantly, adds tools for Bayesian inference and model selection. In this tutorial, we provide an in-depth introduction to the Bayesian features: We review order-constrained Bayesian p -values, DIC and Bayes factors, building on the data, models, and prior QTest based frequentist data analyses of an earlier (frequentist) tutorial by Regenwetter et al. (2014).
Abstract 2540: Mitotic Golgi vesiculation enables human papillomavirus to evade cGAS/STING

Oncogenic human papillomaviruses (HPVs) infect and replicate in differentiating mucosal epithelium, causing 5% of cancers worldwide and essentially all cervical cancers. During infection, HPV must traffic viral genome (vDNA) to the nuclei of basal keratinocytes. Minor capsid protein L2 facilitates intracellular transport of vDNA to the Golgi; upon mitosis, the L2-vDNA complex penetrates limiting membranes and localizes to mitotic chromosomes, ensuring infection of both daughter cells. Cytosolic DNA sensor cGAS recognizes cytosolic dsDNA and produces second messenger cGAMP; cGAMP causes activation and relocalization of ER-resident STING to the Golgi, where it recruits TBK1 to phosphorylate and activate IRF3, initiating a type-I IFN response. The cGAS/STING pathway is assumed, though never demonstrated, to be inactive during mitosis to avoid detecting self-DNA. Since the Golgi is a platform for STING/TBK1/IRF3 recruitment and activation, we hypothesize natural Golgi dispersal deactivates cGAS/STING during mitosis. Further, we hypothesize HPV has evolved to traffic to and translocate from the mitotic Golgi as an immunoevasive tactic to avoid detection by cGAS/STING during mitosis. HaCaTs, a human keratinocyte line, were transfected with DNA or infected with HPV pseudovirions and analyzed for cGAS/STING activation. DNA transfection resulted in IRF3 phosphorylation and nuclear translocation, and STING translocation to the Golgi, indicating cGAS/STING activity. Strikingly, chemical disruption of the Golgi ribbon potently blocked IRF3 activation in response to foreign DNA, suggesting Golgi morphology might modulate cGAS/STING activity during mitosis. In accordance, DNA-dependent IRF3 phosphorylation was transiently reduced in synchronized mitotic cells, but chemical impairment of mitotic Golgi vesiculation enabled cGAS/STING activation, even without foreign DNA transfection. Further, HPV infection resulted in minimal IRF3 phosphorylation, indicating HPV can efficiently evade detection during initial infection. To determine if HPV’s unique trafficking enables evasion, we used cationic liposomes to permit premature virion translocation across limiting membranes. Such treatment renders a non-infectious, translocation-defective mutant HPV infectious, yet susceptible to cGAS/STING sensing. Overall, the cGAS/STING pathway may be inactivated by mitotic Golgi dispersal, allowing HPV to evade detection during mitosis. Citation Format: Brittany L. Forte, Shauna M. Bratton, Samuel K. Campos. Mitotic Golgi vesiculation enables human papillomavirus to evade cGAS/STING [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 2540.
‘No politics … We’re a Mardi Gras now’: Telling the story of LGSM in 21st-Century Britain

What does it mean that Pride was released in 2014, 30 years after the formation of Lesbians and Gays Support the Miners (LGSM) and the same year in which a Conservative government made same-sex marriage a legal reality in the UK? In this article, I explore the narrativising of LGSM’s story, in order to consider how nostalgia operates in the film. Chiefly, I consider the choices that the screenwriter, Stephen Beresford, made in reconstructing the story of LGSM, and examine what these choices reveal about the changes that have taken place in the political landscape of gay Britain over the last 30 years. Through an analysis of these choices, I argue that Pride offers contemporary audiences a story of radical LGBTQ activism that they can enjoy and celebrate, while side-stepping uncomfortable questions regarding identity politics, single issue politics and the demise of collectivist politics.
The Decline of the American Middle Class: Evidence from the Consumer Expenditure Surveys 1988–2015

In 2010, the US Department of Commerce, commissioned by the White House Middle Class Task Force, recommended six indicators that define the middle class: having one’s own home, a car or two in the carport, taking a family vacation every year, sending kids to college, and having some retirement savings. We used the Consumer Expenditure Survey (CE) data to estimate the size of American middle class in selected years from 1988 to 2015 using three empirical variations of this definition and to test if there were upward or downward trends during these years. We found that the size of the American middle class was definitely on the decline between 1988 and 2015 for all three definitions. Multivariate analyses show that variations in total household annual expenditure and sociodemographic variables could not explain the decline. In fact, adjusting for these controls made the decline of the middle class over time more severe.
Stent treatment of ostial branch pulmonary artery stenosis: initial and medium-term outcomes and technical considerations to avoid and minimise stent malposition.

Objective:Stenting of ostial pulmonary artery stenosis presents several unique challenges. These include difficulty in defining anatomy and need for precise stent placement in order to avoid missing the ostial stenosis or jailing either the contralateral branch pulmonary artery or the ipsilateral upper lobe branch.Design:A retrospective review of outcomes was conducted in 1.5 or 2-ventricle patients who underwent stent placement for ostial branch pulmonary artery stenosis. Specific catheterisation lab techniques were reviewed.Results:Forty-seven branch pulmonary arteries underwent stent placement for ostial stenosis in 43 patients. The median age and weight were 3.7 (0.3–18.1) years and 14.2 (5.6–70.0) kg, respectively. Three (2–8) angiographic projections were needed to profile the ostial stenosis. Open-cell stents were used in 23 and stents were modified in 5 cases. Following stent implantation, the minimum diameter improved from 3.6 (0.8–10.5) to 8.1 (4.2–16.5) mm (p < 0.001). The gradient improved from 21 (0–66) to 4 (0–27) mmHg (p < 0.001). Stent malposition occurred in eight (17%) of the stents placed. Five migrated distally causing suboptimal ostial coverage necessitating placement of a second stent in four. Three migrated proximally and partially jailed the contralateral pulmonary artery. Intentional jailing of the upper lobe branch occurred in four additional cases. At a follow-up of 2.4 (0.3–4.9) years, 15 stents underwent further dilation and 1 had a second stent placed within the exiting stent.Conclusion:Ostial branch pulmonary artery stenosis may require additional angiography to accurately define the ostial stenosis. Treatment with stents is effective but carries high rates of stent malposition.
The Invisible Enclosure: How Community Supervision Inhibits Successful Reentry

The use of community supervision in the United States has dramatically increased over the past 40 years. Today, there are 4.5 million individuals on community supervision in the United States, near...
TLPCM: Transfer Learning Possibilistic $C$ -Means

Traditional machine learning and data mining have made tremendous progress in many knowledge-based areas, such as clustering, classification, and regression. However, the primary assumption in all of these areas is that the training and testing data should be in the same domain and have the same distribution. This assumption is difficult to achieve in real-world applications due to the limited availability of labeled data. Associated data in different domains can be used to expand the availability of prior knowledge about future target data. In recent years, transfer learning has been used to address such cross-domain learning problems by using information from data in a related domain and transferring that data to the target task. In this article, a transfer-learning possibilistic c -means (TLPCM) algorithm is proposed to handle the PCM clustering problem in a domain that has insufficient data. Moreover, TLPCM overcomes the problem of differing numbers of clusters between the source and target domains. The proposed algorithm employs the historical cluster centers of the source data as a reference to guide the clustering of the target data. The experimental studies presented here were thoroughly evaluated, and they demonstrate the advantages of TLPCM in both synthetic and real-world transfer datasets.
Transferrable property relationships between magnetic exchange coupling and molecular conductance

Calculated conductance through Aun–S–Bridge–S–Aun (Bridge = organic σ/π-system) constructs are compared to experimentally-determined magnetic exchange coupling parameters in a series of TpCum,MeZnSQ–Bridge–NN complexes, where TpCum,Me = hydro-tris(3-cumenyl-1-methylpyrazolyl)borate ancillary ligand, Zn = diamagnetic zinc(II), SQ = semiquinone (S = 1/2), and NN = nitronylnitroxide radical (S = 1/2). We find that there is a nonlinear functional relationship between the biradical magnetic exchange coupling, JD→A, and the computed conductance, gmb. Although different bridge types (monomer vs. dimer) do not lie on the same JD→Avs. gmb, curve, there is a scale invariance between the monomeric and dimeric bridges which shows that the two data sets are related by a proportionate scaling of JD→A. For exchange and conductance mediated by a given bridge fragment, we find that the ratio of distance dependent decay constants for conductance (βg) and magnetic exchange coupling (βJ) does not equal unity, indicating that inherent differences in the tunneling energy gaps, Δe, and the bridge–bridge electronic coupling, HBB, are not directly transferrable properties as they relate to exchange and conductance. The results of these observations are described in valence bond terms, with resonance structure contributions to the ground state bridge wavefunction being different for SQ–Bridge–NN and Aun–S–Bridge–S–Aun systems.
A National Project to Implement TQM on Dairy Farms

Total Quality Management (TQM) is a management approach that focuses on producing high quality product (as defined by the consumer) by understanding and identifying the sources of variation in the processes of production, developing an ethic of quality within the workforce, and monitoring variation in production.
Clinical analysis of treatment and postoperative efficacy in neonatal congenital pyriform sinus fistula

Objective:To discuss the diagnosis and treatment of congenital pyriform sinus fistula（CPSF） in newborn. Methods:Clinical data of 5 patients with CPSF innewborn were reviewed and the clinical symptoms, auxiliary examinations, surgical methods were analyzed after the operation, patients were followed up closely at different stages. Results:All the 5 neonates successfully completed the surgery without pharyngeal fistula, dysphagia, perifistula and distal fistula infection. Follow-up survey ranged from 3 months to 2 years and no one recurred. Conclusion:Neonatal CPSF is a rare disease with a short course of disease and rapid progression. In severe cases, it may threaten life and should be treated in time.
Benchmark Keystroke Biometrics Accuracy From High-Stakes Writing Tasks

Biometrics are physical or behavioral human characteristics that can be used to identify a person. It is widely known that keystroke or typing dynamics for short, fixed texts (e.g., passwords) could serve as a behavioral biometric. In this study, we investigate whether keystroke data from essay responses can lead to a reliable biometric measure, with implications for test security and the monitoring of writing fluency and style changes. Based on keystroke data collected from a high-stakes writing testing setting, we established a preliminary biometric benchmark for detecting test-taker identity by using features extracted from their writing process logs. We report a benchmark keystroke biometric accuracy of equal error rate of 4.7% for identifying same versus different individuals on an essay task. In particular, we show that the inclusion of writing process features (e.g., features designed to describe the writing process) in addition to the widely used typing-timing features (e.g., features based on the time intervals between two-letter key sequences) improves the accuracy of the keystroke biometrics. The proposed keystroke biometrics can have important implications for the writing assessments administered through the remotely proctored tests that have been widely adopted during the COVID pandemic. © 2021 Educational Testing Service
abmR: an R package for agent-based model analysis of large-scale movements across taxa

O_LIAgent-based modeling (ABM) shows promise for animal movement studies. However, a robust, open-source, and spatially explicit ABM coding platform is currently lacking. C_LIO_LIWe present abmR, an R package for conducting continental-scale ABM simulations across animal taxa. The package features two movement functions, each of which relies on the Ornstein-Uhlenbeck (OU) model. C_LIO_LIThe theoretical background for abmR is discussed and the main functionalities are illustrated using two example populations. C_LIO_LIPotential future additions to this open-source package may include the ability to specify multiple environmental variables or to model interactions between agents. Additionally, updates may offer opportunities for disease ecology and integration with other R movement modeling packages. C_LI
Ecology of Tidal Freshwater and Estuarine Tubificidae (Oligochaeta)

There is an abrupt shift in the community composition of Tubificidae as one proceeds from tidal freshwater to estuarine habitats. Not only does the species composition change but also their relative trophic importance and, to a more variable degree, their importance to the community. Communities from tidal freshwater areas tend to resemble the fauna of large eutrophic lakes while the fauna of estuarine areas is comprised mainly of estuarine endemic and euryhaline marine species. Tidal freshwater forms tend to be larger than estuarine forms and are the major sediment burrowers and bioturbators. Estuarine forms do not appear to be important bioturbators. Competition or interaction with the large and diverse polychaete fauna most likely lessens the importance of oligochaetes in estuarine areas. Where pollution or other factors result in extreme environmental conditions or reduced habitat diversity, estuarine tubificids tend to become more important, while in tidal freshwater areas these conditions result in little change in community composition. The common bond between the faunas inhabiting tidal freshwater and estuarine areas is their opportunistic nature.
Vindiciae, Contra Tyrannos: or, Concerning the Legitimate Power of a Prince over the People, and of the People over a Prince

The Vindiciae, contra tyrannos was the most infamous of the monarchomach treatises produced during the French wars of religion, and continued to be revered (or execrated) as a key part of the radical canon for well over a century after its publication. It is one of the first attempts to advance a systematic justification, with interlocking secular and religious arguments, of resistance against legitimately constituted political authority. This edition presents the first complete and accurate English translation of the work, a comprehensive apparatus, and an introduction which provides the first detailed analysis of the argument and also reconsiders the much-disputed question of authorship. It will be of interest to a wide range of scholars working on the history of political thought and early modern Europe.
Like a dog Walking on its Hind Legs: Samuel Johnson and Quakers

Samuel Johnson liked some individual Quakers but disliked the sect; an examination of his encounters with them, as reported in Boswell's Life, along with reminiscences of the Lloyd family, Mary Knowles and Anna Seward, throws significant light on both Johnson's religious and social views and on some aspects of the Quakerism of his time. The commonly-held view of Quakerism in the Quietist period is, in W. C. Braithwaite's phrase, that these were 'years of outward respectability and inward spiritual decline'. He adds that 'religion as a whole was suffering from the lassitude of Dissent and the devastations of Deism'. Kathryn Damiano challenges many of these perceptions of the Quietist period, arguing that the process of spiritual formation for Friends of this period combined both the negative way, denial of the world, the disciplines of silence, waiting, plainness, and the affirmative way sustained by the community of faith, which encourages faithfulness, transformation and nurture of the inward life. These issues underscore aspects of Quakerism which most trouble Johnson, notably the participation of women in vocal ministry, trust in the leading of an inward light, and the emphasis on the authority of the individual conscience. Boswell, Knowles and Seward each report Johnson's vehement denunciation of a young woman who has become a Quaker. It is clear that death and the final judgment-about which the company had been talking-terrified Johnson. In his attack on Mary Knowles and her protegee, we are seeing that terror being expressed for the young woman, whose immortal soul Johnson believes she has frivolously put at risk. For Johnson, there is no greater danger to one's immortal soul than departing from the faith one was born into. He feared standing before the Almighty and justifYing himself on his knowledge, rather than on his obedience. Providence has placed each of us, and obedience to what has been given one, is safety. Mary Knowles argues that God will understand and forgive human error and look only at whether we follow conscience, mistaken or not. Even these brief glimpses of Quaker lives reveal nuances to the conventional views of eighteenth-century Quakerism. Mary Knowles in particular evidences a far more energetic faith than portrayed by W.C. Braithwaite; in her we see a strong, independent, well-educated woman, capable of inspiring an admiration of Quakerism in others, able to move easily and ©The Continuum Publishing Group Ltd 2002, The Tower Building, 11 York Road, London SEl 7NX and 370 Lexington Avenue, New York, NY 10017, USA.
Properties of the Passive Film Formed on Interstitially Hardened AISI 316L Stainless Steel

Abstract The passive-film on interstitially hardened AISI 316L stainless steel was studied in 0.1 M NaCl solution using electrochemical impedance spectrometry (EIS) and surface analytical techniques. The interstitially hardened AISI 316L was achieved via low-temperature paraequilibrium carburization. EIS experimental data were fitted and analyzed by an equivalent-circuit model that incorporated two time constants: one representing the properties of the carburized layer and one representing those of the passive film. To validate the model a series of samples with varying carburized layer thickness were prepared by successive polishing. In addition to EIS, these samples were analyzed by XPS (X-ray photoelectron spectrometry) to determine the chemical composition of the passive film and carburized layer. A consistent correlation was observed between the EIS response and the chemical compositions of the passive film and carburized layers. Supporting data from long term immersion tests are also reported.
Management of Vaginosis

Although trichomoniasis and bacterial vaginosis represent opposite ends of the clinical spectrum (vaginitis versus vaginosis) and are due to entirely different pathogenic mechanisms, they nevertheless share several characteristics. Common manifestations include a malodorous vaginal discharge, a massive disruption of the normal lactobacillus-dominant flora, elevated pH, and overgrowth of vaginal anaerobes. What these 2 conditions have most in common is an exquisite susceptibility to nitroimidazole agents. For many years, oral multidose metronidazole was the only available nitroimidazole for the indication; however, the recent availability of single dose, long-acting secnidazole offers a useful alternative to conventional therapy. Moreover, although several new options are now available for the treatment of bacterial vaginosis, namely vaginal clindamycin and metronidazole gel, no vaginal regimens are available for the treatment of trichomoniasis. Finally, while clindamycin availability ensures safe treatment of bacterial vaginosis in pregnancy, nitroimidazole therapy is not endorsed for use in the first trimester of pregnancy, and this therapeutic need remains unanswered.
9 Mixing and combining rules

Publisher Summary Equations of state have been used for the accurate description of the P-v-T behavior and thermodynamic properties of fluids for decades. It is mixing and combining rules that allow an equation of state developed for pure fluids to be used for mixtures. Historically, there have been many examples in which an equation of state could be used to describe the properties of two or more pure fluids, but not of their mixtures. This is clearly a failure of the mixing and/or combining rules used. For almost a century, only the simplest mixing rules were widely used; the classical van der Waals one-fluid rules for cubic equations of state, and mixing rules based on the virial equation for more complicated equations of state. In recent years, there has been a great deal of research on mixing rules and some real advances. Perhaps the most important has been the combination of equation of state and free energy models. These mixing rules, discussed in this chapter, have resulted in simple cubic equations of state providing accurate descriptions of the phase behavior of highly nonideal mixtures over large ranges of temperature and pressure with temperature-independent parameters. Further, these new mixing rules can incorporate mixture group contribution methods, such as UNIFAC, allowing for a simple extension of these models to high temperatures and high pressures with the existing parameter tables. New mixing rules have also been developed for other classes of equations of state. In this area, the progress has been slow and less noteworthy. One interesting feature that has emerged, largely from molecular theory, is the use of different mixing rules for the attractive and repulsive contributions to the equation of state.
Role of Methionine in Bacterial Chemotaxis

Abstract The effect of methionine starvation on the motility and behavior of normal and nonchemotactic mutants of Salmonella typhimurium was investigated. Methionine starvation eliminates tumbling in the wild type, but fails to do so in an uncoordinated (frequent tumbling) mutant. In the mutant, methionine starvation significantly extends the period of smooth motility that follows a sharp temporal increase of attractant. These results suggest that methionine metabolism is not tightly coupled to the generation of tumbles, but rather is necessary for the return of some tumble-regulating parameter to a steady-state level.
Validation of oblique image real-time reorientation from short axis (SA) slices during myocardial perfusion SPECT interpretation

2531 Objectives Accurate detection and localization of significant coronary artery disease requires correct and consistent orientation of myocardial perfusion image (MPI) slices. Physicians during image interpretation not uncommonly disagree with original oblique angle selection resulting in either suboptimal interpretation or off-line reorientation and delayed interpretation. To develop a software tool to allow real-time oblique angle slice re-orientation during MPI interpretation within the Emory Cardiac Toolbox™ (ECTb). Methods Stress or rest data is identified for adjustment, angles are interactively set on reference mid vertical or horizontal long axis, and a new SA dataset is produced without the need for reconstruction. To validate whether this approach yielded similar diagnostic results compared to re-reconstructing and re-selecting the correct oblique angles, 20 99mTc stress tetrofosmin studies (15 males) were used. Studies were reconstructed and re-oriented by a single operator in several iterations: correct angles (CORR1), transaxial (TX) +10 degrees, TX -10 degrees, vertical long (VLA) +15 degrees, VLA -15 degrees. Reconstruction was repeated correctly in a separate session (CORR2). Perfusion defect extent (DE) was calculated from CORR1 slices using ECTb. For each non-CORR image set with significantly different DE from CORR1 results, oblique angles were adjusted in real-time using the new tool and re-analyzed. Results CORR1 DE matched CORR2 DE in 90% of LAD (18/20), 90% of LCX (18/20) and 95% of RCA (19/20) territories. With incorrect orientation, there were 18 instances of clinically significant changes vs CORR1 in at least one coronary territory, involving 10 of the 20 patients. After angle adjustment, correct DE was obtained for 100% of LAD (18/18), 83% of LCX (15/18) and 94% of RCA (17/18) instances. Conclusions Using a new software tool, image slice orientation can be corrected in real-time during MPI review. Corrected slices yield similar quantitative results to original correct slices.
High performance compilers for ASIC designs

An explanation is given of why it is important for an IC designer to consider the use of precompiled modules such as RAM, ROM, and multipliers in application-specific IC (ASIC) circuits. The advantages in IC performance and the subsequent improvement in the overall system performance are explained. Examples of compiled memories and multipliers are compared to give the reader an idea of the performance and size requirements of the modules as they would perform on an ASIC circuit. Also described are the options that are inherent in the compiler routines and how these options allow designers to optimize the design of ASIC circuit in a way that would not be possible without the compiled modules. >
No Static at All

Permeability of the intestinal epithelial barrier is regulated in response to physiological and pathophysiological stimuli. Recent work has characterized a critical role of acute tight junction regulation in diarrhea secondary to T cell activation and cytokine release. The intracellular mediators of the ensuing barrier dysfunction include myosin light chain kinase, which phosphorylates myosin II regulatory light chain and triggers structural tight junction reorganization. While the molecular intermediates in this reorganization are not defined, the new discovery that individual tight junction-associated proteins are highly dynamic at steady state may provide insight into the mechanisms of regulation.
Long term high temperature oxidation resistance of a nanoceria coated 316 SS under dry air conditions

Abstract In this work, nanoceria dip coated and uncoated 316 stainless steels were exposed to dry air at 1073–1273 K for times of up to 250 h. From this work, measured activation energies, Q = 256 kJ mol − 1 and Q = 240 kJ mol − 1 were found for coated and uncoated 316 SS, respectively. In the coated steel, the activation energy for oxidation cannot be attributed to a single mass transport mechanism. In addition, the scale morphologies, as well as the dominant oxide phases were determined by X-ray diffraction means. It was found that in the nanoceria dip coated steels, the scale was fine grained and highly adherent. Oxidation at increasing temperatures in the coated steels favored the development of the spinel ((Mn, Cr) 3 O 4 structure and at 1273 K with the presence of Fe 2 O 3 was severely hindered. In contrast, in the uncoated steel, a relatively thick scale, predominantly Fe 2 O 3 developed and it exhibited severe damage through spallation and detachment from the steel substrate. Also, the resultant grain structure was rather coarse and it consisted of faceted grains with continuous nucleation/growth at grain ledges.