cssi/SciSciGPT-SciSciNet huggingface dataset:
Abused South Korean Women A Comparison of Those Who Do and Those Who Do Not Resort to Lethal Violence

This study compares two groups of women in South Korea: one group incarcerated for the deaths of their male partners and the other staying in a shelter for battered women. The analysis serves to answer two questions: First, are the findings regarding women who kill their intimate partners in Western societies generally applicable to their counterparts in South Korea? Second, how are abused South Korean women who resort to lethal violence against their abusers different from those who do not? Regarding both abused and nonabused women incarcerated for criminal homicide against their partners, results indicate that they have less experience of psychological and physical abuse by their partners and that they are less educated, underemployed, and more supportive of traditional patriarchal norms than are the women who utilize domestic violence shelters. This research explores implications for intervention strategies to encourage abused women to seek help from legal and extralegal sources.
Atypical repair on Pap smears: Clinicopathologic correlates in 647 cases

The Bethesda system separates atypical reparative changes (ARC) from "typical" repair and places it into the atypical squamous cells of undetermined significance (ASC-US) category. The cytologic diagnosis of ARC represents both diagnostic and management challenges because its clinical significance is controversial and has not been fully investigated. On the basis of scant literature on follow-up of women with ARC on Papanicolaou (Pap) test, we reviewed data from our patient population, which consists of a mixture of low- and high-risk women. Six hundred forty-seven patients with ARC on their Pap tests were identified in a 7-yr period. Of this, 189 (29%) women were lost to follow-up. Of the 458 women with follow-up, 31% had cervical biopsies and 69% were followed by repeated Pap tests. The age ranged from 16 to 86 (mean 47 yr). The incidence of squamous intraepithelial lesion was 5.2% (5% low-grade and 0.2% high-grade). Most women (62%) with ARC on Pap test had a benign condition on follow-up. For some women, the immediate cause was not known and the Pap abnormality resolved spontaneously. Our study questions the validity of reporting ARC within the ASC-US category.
Analysis of fluorinated proteins by mass spectrometry.

19F NMR has been used as a probe for investigating bioorganic and biological systems for three decades. Recent reviews have touted this nucleus for its unique characteristics that allow probing in vivo biological systems without endogenous signals. 19F nucleus is exceptionally sensitive to molecular and microenvironmental changes and thus can be exploited to explore structure, dynamics, and changes in a protein or molecule in the cellular environment. We show how mass spectrometry can be used to assess and characterize the incorporation of fluorine into proteins. This methodology can be applied to a number of systems where 19F NMR is used.
Designing Products and Services for Consumer Welfare: Theoretical and Empirical Issues

In this paper we examine the theoretical and empirical issues that arise for a public-sector decision maker who wishes to use the target population's preferences as an input for designing new products and services. The marketing literature suggests using essentially the same approach as that for the private-sector problem, with one exception. Instead of maximizing profits, share or volume, the sum-of-benefits to society is maximized. However, the social welfare literature has suggested several other measures of welfare and shows that no single welfare function dominates all others. Therefore, to choose an appropriate welfare function to maximize the decision maker must first examine the theoretical and empirical similarities between the alternatives. For six prominent welfare functions, we examine the theoretical differences in terms of the notion of fairness promoted and the kind of preference data required. Empirically, we examine the similarities in social rankings and first choices induced by these welfare functions under various preference configurations. We also examine their sensitivity to measurement error and preference normalization.
The effect of lucanthone on sublethal radiation damage, in vivo

Abstract The capacity of the Chinese hamster jejunal crypt cell to accumulate and repair sublethal radiation damage was determined by analyzing the return of the shoulder of the radiation dose-crypt microcolony survival curve (Dr) after a priming dose of 1250 rad. The control split dose crypt cell survival curve exhibited a D0, Dr and “n” of 179 ± 3 rad, 261 ± 3 rad and 4.3 respectively; repair of sublethal radiation damage was completed by two hours post-irradiation. The effect of lucanthone (an antischistosomal DNA intercalating agent) on the crypt cell's capacity to accumulate and repair sublethal radiation damage was determined by injecting the drug (100 mg/kg, i.p.) at intervals before irradiation with a priming dose of 1250 rad, followed two hours later by graded doses. Injection coincident with the priming dose of radiation resulted in a 22 rad reduction of the Dr (compared to control Dr). Injection eight hours before the priming dose almost completely inhibited the accumulation and repair of sublethal radiation damage so that the resultant Dr two hours later was only 29 rad (a 232 rad reduction). At no time was the D0 of the crypt cell survival curve affected by lucanthone. These data confirm previous results from whole crypt analysis and LD 50 7 , analysis that non-toxic concentrations of lucanthone reversibly inhibit the accumulation and repair of sublethal radiation damage in a time-dependent manner with complete inhibition approximately eight hours post-injection. This drug is useful for the study of sublethal radiation damage in vivo and may be beneficial in radiation therapy of cancer when it is desirable to inhibit the repair of sublethal radiation damage.
Signal-to-noise ratio-enhancing joint reconstruction for improved diffusion imaging of mouse spinal cord white matter injury

Purpose To assess the capability of signal-to-noise ratio enhancing reconstruction (SER) to reduce the acquisition time for quantitative white matter injury assessment. Methods Four single-average diffusion tensor imaging (DTI) datasets were acquired for each animal from four mouse cohorts: two models of spinal cord injury and two control groups. Quantitative parameters (apparent diffusion coefficient, relative anisotropy, axial and radial diffusivities) were computed from (I) single-average data with traditional reconstruction; (II) single-average data with SER; (III) four-average data with traditional reconstruction; and (IV) single-average data with optimized multicomponent nonlocal means (OMNLM) denoising. These approaches were compared based on coefficients of variation (COVs) and whether estimated diffusion parameters were sensitive to injury. Results SER yielded better COVs for diffusivity and anisotropy than traditional reconstruction of single-average data, and yielded comparable COVs to that achieved with four-average data. In addition, diffusion parameters obtained using SER with single-average data had comparable injury sensitivity to those obtained from four-average data, while diffusion parameters obtained from OMNLM and traditional reconstruction of single-average data had limited sensitivity. Conclusion A four-fold reduction in the number of averages for quantitative diffusion imaging of small animal white matter injury is feasible using SER. Our results also underscore the need to validate nonlinear methods using task-based measures on an application-by-application basis. Magn Reson Med, 2015. © 2015 Wiley Periodicals, Inc.
A Natural Deduction System

This chapter introduces another formal system of axioms and inference rules for deducing proofs that propositions are tautologies. It is called a “natural-deduction system” because it is meant to mimic the patterns of reasoning that we “naturally” use in making arguments in English.
Torque Estimation in a Wrist Rehabilitation Robot Using a Nonlinear Disturbance Observer

In this paper, we present implementation of a nonlinear disturbance observer algorithm to estimate disturbance torques on a wrist rehabilitation robot. The ultimate goal is to enable accurate estimation of user interaction torques without force/torque sensors. A dynamic model of the Wrist Gimbal two degree-of-freedom forearm and wrist exoskeleton is developed. A nonlinear disturbance observer (NDO) algorithm that incorporates the robot dynamics is implemented. Friction models for both joints of the robot are identified. The robot dynamic model and the accuracy of the disturbance torque estimations are experimentally verified under closed-loop trajectory tracking scenarios.Copyright © 2015 by ASME
Lysosome and Endosome Organization and Transport in Neurons

Endosomal and lysosomal pathways in neurons are critical for responding to extracellular signals, dissociating signals from receptors, recycling of synaptic vesicles, and downregulating receptors, as well as for the phagocytosis of viruses and bacteria. Recent work has demonstrated the importance of microtubules and actin filaments as substrates for endosome and lysosome transport by motor proteins and maintenance of organelle positioning within cells. The Rab family of small guanosine triphosphatases controls endosome and lysosome movement by selecting sites of vesicle formation on endomembranes and recruiting coat proteins and motors to nascent vesicles. Failure of endosome–lysosome transport pathways in neurons can result in neurodegenerative disease.
Synergistic hybrid organic-inorganic aerogels.

A class of inorganic–organic hybrid mesoporous aerogel structure was synthesized by growing gel in a gel. In Type 1, silica gels were grown inside the macropores of thermoreversible syndiotactic polystyrene (sPS) gel, while Type 2 hybrid aerogels were obtained by thermoreversible gelation of sPS chains in the mesopores of preformed silica gel. The hybrid gels were converted into aerogels by exchanging the solvent with liquid carbon dioxide followed by supercritical drying. The hybrid aerogels presented cocontinuous networks of pearl-necklace silica particles and crystalline strands of sPS and exhibited the “petal effect” due to the presence of superhydrophobic sPS and hygroscopic silica. The compressive modulus and compressive strain show large enhancements over sPS and silica aerogels indicating synergy, although Type 1 hybrid aerogels were found to be more robust. The hybrid aerogels showed fast absorption and high absorption capacity for a representative hydrocarbon liquid.
Antibiotic combinations and resistance: response of E. coli to antibiotics, singly and in pairs.

Summary and ConclusionThe data presented confirm and extend the observations previously made with staphylococci and some streptococci using other antibiotic combinations. For E. coli, and within the limitations of the methods employed, it was shown that following repeated subcultures in pairs of antibiotics, resistance generally developed more slowly and to a smaller degree than when the same organisms were exposed to the same antibiotics individually. There were wide variations, however, depending mainly on the antibiotics used, but perhaps also with the strain of organism. Cross-resistance to neomycin frequently accompanied increases in resistance to streptomycin resulting from exposure to the latter, alone or in combinations. Likewise, cross-resistance to oxytetracycline and chlortetracycline from exposures to chloramphenicol and to chloramphenicol and chlortetracycline following subcultures on oxytetracycline accompanied the development of resistance to the homologous antibiotic, whether present alone...
High Quality NiFe/Ag Superlattices Made by Pulsed Laser Deposition (PLD)

High-quality thin-film superlattices of permalloy (NiFe) and silver (Ag) have been grown by pulsed laser deposition (PLD) for the first time. The alternating metallic layers weregrown from individual NiFe and Ag targets utilizing an automated multi-target holder coupled to a conventional PLD system. The targets were ablated at a base pressure of 4×10−7 Torr and the material deposited on room-temperature (100) silicon and on fused silica substrates. The films were characterized by X-ray diffraction (XRD), magnetic field-dependent resistivity, and ferromagnetic resonance (FMR). XRD was used to confirm uniform bilayer thicknesses. The magnetic field-dependent resistance measurements indicated the presence of magnetoresistance in the deposited films. An as-deposited film with a bilayer thickness of 75 A demonstrated a roomtemperature magnetoresistive effect of 0.15 %. FMR has been used to determine the relationship between NiFe magnetism and the observed magnetoresistance.
Ecosystem Services of Woody Crop Production Systems

Short-rotation woody crops are an integral component of regional and national energy portfolios, as well as providing essential ecosystem services such as biomass supplies, carbon sinks, clean water, and healthy soils. We review recent USDA Forest Service Research and Development efforts from the USDA Biomass Research Centers on the provisioning of these ecosystem services from woody crop production systems. For biomass, we highlight productivity and yield potential, pest susceptibility, and bioenergy siting applications. We describe carbon storage in aboveground woody biomass and studies assessing the provision of clean and plentiful water. Soil protection and wildlife habitat are also mentioned, in the context of converting lands from traditional row-crop agriculture to woody production systems.
Relationships between County Health Rankings and child overweight and obesity prevalence: a serial cross-sectional analysis

The County Health Rankings (CHR) system provides health rankings for U.S. counties. These factors may have utility for evaluating and predicting health outcomes. This study examined the association between CHR factors and the prevalence of child overweight/obesity (OWOB) in the state of Pennsylvania over 3 years. The prevalence of childhood OWOB was obtained for all Pennsylvania school districts for the 2009-10 through 2011-12 school years. Correlational and inferential statistical analyses were used to examine the associations between the prevalence of OWOB in grades K-6 (OWOB1) and 7-12 (OWOB2) and z-score for the overall CHR Health Factors rank, as well as for individual predictive factors (Health Behaviors, Clinical Care, Social and Economic Factors and Physical Environment). Low to moderate correlations (0.29–0.43) were found between OWOB1 and CHR factors. Weaker and less consistent correlations were found for adolescents. There was a significantly higher prevalence of OWOB in counties with poorer CHR scores. County-level adult indicators of health are significantly associated with levels of child obesity. Future studies should examine the relationship between CHR and other health outcomes.
Significance of Evidence-based Medicine to Pediatric Clinical Teaching

The core of evidence based medicine is to connect the clinical evidence,personal experience and the actual condition and wish of the patient in clinical decision making.It gives valuable enlightenment to clinical education,and it's an inevitable tendency of modern clinical education,which has significant impact on clinical education of paediatrics.
Analysis of the factors affecting aluminum industry electricity consumption

The article describes the electricity consumption situation of China's nonferrous metals industries,puts forward major factors and its classification which impact power utility of non-ferrous metals industry.Focusing on the aluminum industries,the article analyzes in-depth the relationship between various factors and electricity consumption.From the point of view of the importance and easy to quantify,it puts forward the main factors impact the aluminum industry power consumption.
The safe introduction of new technologies into neonatal medicine

In neonatal medicine, there is a technologic revolution in progress. During the past 10 years, we witnessed the introduction and improvement of monitoring equipment, the development of new modes of assisted ventilation, and the proliferation of extracorporeal membrane oxygenation. This article reviews how we might improve the process of the safe introduction of new technologies into neonatal medicine.
Zygmunt Zawirski: A Short Bio-Bibliography (28. IX.1882 - 2. IV.1948)

Zygmunt Michal Zawirski was born at Berezowica Mala, in the Polish (then Austrian) province of Tarnopol.
Creating immunocompromised districts.

We read the letter to the editor, Viral warts and seborrheic keratosis on tattoos: a review of 9 cases with great interest.1 Dermatologists see only what they know! Once we recognized the possibility that warts might grow preferentially in black and blue tattoo dye, we collected 7 cases over a 10-year period from one solo private practice. In this report, a patient with a pre-existing viral wart on skin adjacent to a new tattoo appears to have preferentially spread onto the immunocompromised district (Ruocco, 2009)2 created by black ink nanoparticles. This article is protected by copyright. All rights reserved.
Laser Microprobe Mass Spectrometry

The use of lasers as an ionization source for solid samples is nearly as old as the laser itself. The first papers in this field were published in 1963 [1]. Since then there has been a growing interest as well as a proliferation of publications on this subject, to the extent that a recent bibliography listed nearly 1000 references [2]. The reasons for this increase in popularity are twofold. First, commercial instruments that use lasers as a microprobe have become available in the last five years. Second, the laser is one of a class of “soft” ionization sources that have become popular in organic mass spectrometry for the analysis of nonvolatile and thermally labile materials. The laser is unique as a means of ionizing solids because the ionization mechanism can be altered by simply changing the power density in the focal spot.
FFTree: A flexible architecture for data center networks towards configurability and cost efficiency

In this paper, we propose a novel data center network architecture named FFTree. Compared to widely adopted industrial solutions including fat-tree, this architecture can provide even higher aggregate bandwidth and richer path availability. Most importantly, FFTree provisions unique flexibility so that its topology and performance can be tailored with great freedom before its deployment. The fine granularity and wide dynamic range of its configurations allow FFTree to exactly fit and closely follow the time-variant demands of its applications. Also, this flexibility facilitates the reuse of network devices, so that upgrades could be achieved by rearranging existing switches, avoiding the expenditure on new generations of hardware in each upgrade cycle. Furthermore, this flexibility allows FFTree to be elaborately tuned into cost efficient zones in the sense that it provides higher bandwidth using less network devices, which leads to significant cost reduction. We design the network topologies of FFTree, propose a set of routing algorithms, and demonstrate its aforementioned features. We also analyze the performance and compare it with its predecessors. Technically, this architecture can be seen as a generalization of fat-tree, and is backward-compatible to fat-tree: it consists of commercial off-the-shelf network devices, and the whole system can cooperate with the hosts running Ethernet and IP. We believe FFTree is ready to be deployed in industry, as a perfect replacement of the classic fat-tree.
Abstract 133: A Systems Genetics Approach to Identify Genetic Pathways and Key Drivers of Isoproterenol-induced Cardiac Hypertrophy and Cardiomyopathy in Mice

Heart Failure (HF) is a complex disease involving numerous environmental and genetic factors. We previously reported a genetic analysis of HF traits in a population of inbred mouse strains treated with isoproterenol, a β-adrenergic agonist used to mimic catecholamine-driven cardiac hypertrophy. We now present a systems genetics analysis in which we have used left ventricular transcript levels from these mice to perform co-expression network modeling. We constructed gene networks composed of 8,126 genes and 20 modules using the wMICA algorithm. In the wMICA network generated from treated hearts, we identified a module with significant correlations to several HF-related phenotypic traits. Further analysis of this module showed significant over-representation of genes known to contribute to the development of HF. Using the causal modeling algorithm NEO, we identified the gene Adamts2 as a putative master regulator of the module. We then validated the role of this gene through siRNA-mediated knockdown in neonatal rat ventricular myocytes (NRVM). Consistent with our model, Adamts2 silencing was able to regulate the expression of the genes residing within the module as well as impairing isoproterenol-induced cell size changes . Our results provide a view of higher order interactions in heart failure with potential to facilitate diagnostic and therapeutic approaches.
Phenology and Genecology of Woody Plants

Phenology and genecology, far from being separate disciplines, cover much ground in common. Until recently, phenology, the study of periodic phenomena in plants and animals, has been limited in practice largely to observation of visible phenomena. The relationship of plant physiological processes to phenologicai events seems obvious, but physiological bases for many phenologicai events have yet to be uncovered. To an increasing extent this is now being done.
Glutaraldehyde cross-linking increases the stability of Lumbricus terrestris erythrocruorin.

Since donated red blood cells must be constantly refrigerated, they are not available in remote areas and battlefields. We have previously shown that the hemoglobin of the earthworm Lumbricus terrestris (LtEc) is an effective and safe substitute for donated blood that is stable enough to be stored for long periods at the relatively high temperatures that may be encountered in remote areas. The goal of this study was to further increase the thermal stability of LtEc by covalently cross-linking LtEc with glutaraldehyde (gLtEc). Our results show that the melting temperatures of the gLtEc samples steadily increase as the molar ratio of glutaraldehyde to heme increases (from Tm = 57°C for native LtEc up to Tm = 68°C at a ratio of 128:1). In addition, while native LtEc is susceptible to subunit dissociation at alkaline pH (8-10), cross-linking with glutaraldehyde completely prevents dissociation of gLtEc at pH 10. Increasing the molar ratio of glutaraldehyde:heme also significantly increased the oxygen affinity of gLtEc, but this effect was decreased by cross-linking gLtEc in the deoxygenated T state. Finally, while gLtEc samples cross-linked at low G:H ratios (e.g., 2:1) exhibited slight increases in oxidation rate in Tris buffer, no significant difference in oxidation rate was observed between native LtEc and the gLtEc samples in Ringer's Solution, which contains antioxidants. Overall, cross-linking LtEc with glutaraldehyde significantly increases its thermal and structural stability without any loss of function, making gLtEc an attractive blood substitute for deployment in remote areas and battlefields. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 34:521-528, 2018.
170-P: SUCCESSFUL RE-TRANSPLANTATION OF AN ADULT SMALL BOWEL TRANSPLANT RECIPIENT IN THE SETTING OF POSITIVE CDC CROSSMATCH

Aim PRA greater than 20%, absence of spleen and use of a nonliver-inclusive intestinal allograft are all predictors of adverse graft survival. Methods A 52-year-old splenectomized male underwent small bowel transplant for short gut syndrome secondary to pseudo obstruction in October 2010. Retrospective T and B cell NIH-CDC crossmatch with extended incubations were negative; thus, no antibody detection was performed. Post transplant course was complicated by biopsy confirmed severe acute cellular rejection. Single antigens on day 10 and day 21 revealed multiple Class I antibodies, but no donor specific antibodies (DSA). Patient was treated with intravenous steroids and Thymoglobulin. The organ was explanted at day 27 post transplant. Results Antibody testing was performed by Luminex in April 2011 prior to relisting. The antibody screen was positive for Class I and negative for Class II. Class I PRA could not be determined due to high background; thus, Class I PRA was performed by CDC method and was resulted as 82%. Multiple Class I anti-HLA antibodies were detected by single antigen, the majority with raw mean MFIs greater than 10,000. All antibodies with MFI greater than 3000 MFI were reported as possible unacceptable antigens: A10(25,26,34, 66), A19 (29,30, 31, 32, 33, 74), A28(68, 69), A43, BW4, B45, B76 and B82. The patient received his second small bowel transplant on June 5, 2011. Retrospective T and B cell NIH-CDC crossmatches with extended incubations were strongly B- and T-cell positive in the absence of identifiable DSA. The patient was treated aggressively and maintained on high level immunosuppression following the second transplant. Eleven months later, the patient has good bowel function and tolerates a general diet. Biopsies at three months and 10 months post were negative for acute rejection. Conclusions This case report illustrates that small bowel transplant can be successful in the setting of multiple pre-transplant predictors of adverse graft survival.
Negative urgency partially accounts for the relationship between major depressive disorder and marijuana problems.

To goal of this study was to better understand mechanisms underlying associations between Major Depressive Disorder (MDD) and marijuana use and problems. Specifically, it was hypothesized that negative urgency (NU), the tendency to act rashly while experiencing negative mood states, would uniquely (compared to other impulsivity traits: positive urgency, sensation seeking, premeditation, and perseverance) account for the relationship between MDD and marijuana use and problems. Data were collected from a sample (N = 357) of veterans (M age = 33.63) recruited from a Veterans Affairs hospital who used marijuana at least once in their lifetime. Participants completed the SCID-NP to assess MDD, a marijuana problems scale, a Time-Line Follow-back to assess six-month marijuana use, and the UPPS-P Impulsive Behavior Scale for impulsivity. Path analysis was conducted using bootstrapped (k = 20,000) and bias-corrected 95% confidence intervals (CIs) to estimate mediation (indirect) effects, controlling for age, sex, and race. Analyses revealed a significant direct effect of MDD on NU and NU on marijuana problems. Regarding mediational analyses, there was a significant indirect effect of MDD on marijuana problems via NU. The direct effect of MDD on marijuana problems was reduced, but remained significant, suggesting partial mediation. No other impulsivity scales accounted for the relationship between MDD and marijuana problems. In predicting marijuana use, there were no significant indirect effects for any impulsivity traits, including NU, despite significant bivariate associations between use and NU and MDD. Results suggest that high levels of NU may partially explain associations between MDD and marijuana problems, but not marijuana use. No other facets of impulsivity accounted for the relationship between MDD and marijuana use or problems, underscoring the specificity of NU as a putative mechanism and the importance of assessing NU in treatment settings.
A Fully Integrated Buck Regulator With 2-GHz Resonant Switching for Low-Power Applications

This paper presents a fully integrated buck regulator design for low-power applications. In order to enable the usage of on-chip inductor for low load current 10–40 mA, the proposed buck regulator is designed with an ultra-high switching frequency at 2 GHz, which is the highest switching frequency reported so far. To reduce the power switch losses, resonant switching scheme is utilized to save the switching clock energy. Tunable slew rate recovery circuits are used to improve the efficiency of the design. The proposed buck regulator has been implemented in 65-nm CMOS technology with a 1.1-V input. Measurement shows a wide output range of 0.3–0.86 V. The proposed design achieves up to 73% power efficiency.
Enhancing Predictive Modeling of Nested Spatial Data through Group-Level Feature Disaggregation

Multilevel modeling and multi-task learning are two widely used approaches for modeling nested (multi-level) data, which contain observations that can be clustered into groups, characterized by their group-level features. Despite the similarity of the problems they address, the explicit relationship between multilevel modeling and multi-task learning has not been carefully examined. In this paper, we present a comparative analysis between the two methods to illustrate their strengths and limitations when applied to two-level nested data. We provide a detailed analysis demonstrating the equivalence of their formulations under a mild condition from an optimization perspective. We also demonstrate their limitations in terms of their predictive performance and especially, their difficulty in identifying potential cross-scale interactions between the local and group-level features when applied to datasets with either a small number of groups or limited training examples per group. To overcome these limitations, we propose a novel method for disaggregating the coarse-scale values of the group-level features in the nested data. Experimental results on both synthetic and real-world data show that the disaggregated group-level features can help enhance the prediction accuracy of the models significantly and identify the cross-scale interactions more effectively.
Commutants of analytic toeplitz operators with automorphic symbol

For a function ~ in H ~ of the unit disk D, the operator on the Hardy of multiplication by ~ will be denoted by T and its commutant by space [T~]'. We consider the special case when ~ is a covering map (in the sense of Riemann surfaces) of D onto a bounded plane domain. For such a function ~, let G be the group of linear fractional transformations I, of D onto D such that o I = ~. (G is isomorphic to the fundamental group of ~(D).) For our purposes it will be sufficient to think of an a/lnulus of inner radius r and outer radius R, 0 ~ r < R < ~, and the mapping ~ obtained by mapping the disk onto the strip log r < Re z < log H followed by the exponential map. The group G in the disk corresponds to the group of translations by 27~qi in the strip. We can characterize the operators that ecmmute with T •
Regulatory features of seminal vesicle development and function.

Publisher Summary This chapter discusses the regulatory features of seminal vesicle development and function. Seminal vesicles or vesicular glands are a special type of secretory organ of the male genital tracts in many but not all mammalian species. These structures differentiate in the fetus from the caudal portion of the Wolffian ducts. The Wolffian duct also serves as the embryonic precursor of the epididymis, the ductus deferens, and, in certain mammals, of the secretory enlargements of the caudal terminus of the vas deferens known as the ampullary glands. Vesicular secretions exhibit great species variations in their chemical compositio, and contain high concentrations of substances that are present in only much smaller amounts in all other body fluids. The fetal morphogenesis of seminal vesicles and their growth and functional differentiation at puberty are strictly controlled by androgens, and are influenced by several other hormones. Testosterone secreted by testicular Leydig cells is the prime hormonal regulator of the fetal morphogenesis of seminal vesicles, of the growth and functional differentiation of these organs at puberty and the maintenance of their adult dimensions and secretory activities.
Parent-rating vs performance-based working memory measures: Association with spoken language measures in school-age children.

Abstract Working memory (WM) assessment is often part of cognitive-linguistic test batteries. The author examined the relationship between parent rating of WM functioning and children’s performance-based WM, and the relationship of each with receptive and expressive spoken language measures. Study participants were eighty-three 7- to 11-year-old children. The sample represented a broad range of cognitive abilities. No participating child had frank neurological or intellectual disabilities, autism, fluency disorder, or hearing loss. Parents completed a standardized executive function rating scale that included a WM subscale. Children completed a standardized WM task and an experimental WM task. Children also completed six standardized language measures. Results showed that there was no correlation between parent rating and either of the performance-based WM tasks as well as the composite WM performance score. Parent rating of WM functioning was not related to any of the language scores whereas the composite WM performance score showed significant links with language abilities. Although parent rating and performance-based WM measures are designed to reflect the same cognitive construct, they are not correlated. Potential reasons for the findings and implications of using parent-rating and performance-based WM measures in school-age children are discussed.
Abundances of Tetracycline Resistance Genes and Tetracycline Antibiotics during Anaerobic Digestion of Swine Waste.

The impact of anaerobic digestion of animal waste on the persistence of antibiotic resistance genes (ARGs) and antibiotics is not widely studied. Two identical, 800-L digesters seeded with swine slurry were followed up to 100 d in three separate trials. The trials received varying amounts of antibiotic-free corn ( L.) mixed with water to maintain the digestion process. Biogas production, seven tetracycline resistance () genes, and three tetracyclines and their transformation products were measured. Biogas production proportionally increased as the feeding loads increased between trials. In Trial 1, log gene copies showed small but statistically significant ( 0.05) effect except for significant reductions in B ( < 0.0001) and G ( = 0.0335) log gene copies. In Trial 3, which received the highest amount of corn mix, log copies of the 16S ribosomal RNA and the genes significantly ( < 0.0001) reduced over time during digestion. Up to 36 μg L tetracycline, 112 μg L chlortetracycline, 11.9 mg L isochlortetracycline, and 30 μg L 4-epitetracycline were detected both in the liquid and solid digestates. Results of this study revealed that although anaerobic digestion of swine waste can produce useful biogas, it does not result in complete removal of bacteria, ARGs, and antibiotics regardless of differences in the feeding loads between trials. Further effluent and sludge treatments are required prior to their downstream use in crop production to minimize emergence and environmental dissemination of antimicrobial-resistant bacteria through animal manure.
In Situ Cs and H Exchange into Gaidonnayite and Proposed Mechanisms of Ion Diffusion

The microporous mineral gaidonnayite Na2ZrSi3O9·2H2O was studied to better understand its ion-exchange mechanisms, specifically for Cs+ and H+ ions. In situ Raman spectroscopy, in situ X-ray diffra...
In-Band Full-Duplex Technology: Techniques and Systems Survey

In-band full-duplex (IBFD) technology can enable unique system capabilities and network architectures by allowing devices to transmit and receive on the same frequency at the same time. While previously considered impossible, this ability can now be used to optimize resource sharing within the crowded frequency spectrum for various communication systems, including 5G new radio. The potential of these IBFD systems can only be realized if each device incorporates a sufficient number of self-interference cancellation techniques to ensure that its receivers do not saturate. This tutorial survey offers the most comprehensive collection to date of these techniques and discusses how all of them can be implemented within the different domains of a typical transceiver. In addition, the results of a novel IBFD system study are presented for more than 50 demonstrated communication systems with more than 80 different measurement scenarios. The various system parameters are then combined into a new figure of merit, which can be used to propel future research and accelerate the inclusion of IBFD technology within an upcoming wireless standard.
Analysis of X-Ray Microtomographic Images to Measure Work of Fracture in Concrete

The fracture problem in concrete has been studied in great depth over the past thirty years. There have been many experimental and analytical attempts to calculate a work of fracture and to gain an understanding of the complex mechanisms of concrete fracture. An emerging theme is the intrinsic three-dimensional nature of the damage that occurs in loaded concrete. This has led to an increase in the amount of interior studies conducted. The insides of concrete have been exposed over the years by, among others, acoustic emission techniques, ultrasonics, dye penetration and radiography [1]. Most recently, x-ray microtomography has been used in order to see into the heart of concrete failure [2].
Incorporating MDMA as an Adjunct in Emotionally Focused Couples Therapy With Clients Impacted by Trauma or PTSD

This article explores incorporating 3,4-methylenedioxymethamphetamine (MDMA) as an adjunct in emotionally focused couples therapy (EFT) with clients in which at least one participant has endured a ...
Mixed Robotic Interface Г : Searching for a hybrid cyber-physical design/experience interface using virtual/actual robots

Mixed Robotic Interface is a project-based design-research investigation, studying new ways of creating hybridized cyber-physical design and experience interfaces, at the intersection of robotics—as its core component, and augmented reality, game design, projection mapping, and digital fabrication. Mixed Robotic Interface Г—as part of Mixed Robotic Interface series of research projects, focuses on using “actual” and “virtual” robot arms as a possible creative medium and extensions of design/gaming environment creating immersive atmospheres for “experiencing” design. This research questions the possibilities of creating an architectural/spatial atmosphere through digitally enhanced experiences. Different from some of the current experiments with augmented reality (AR), virtual reality (VR) and projection-mapping in architecture, Mixed Robotic Interface Г is not looking into “immersive” experience as a way to “blur” the boundaries of digital and physical—similar to virtual reality experience with headsets. Instead, Mixed Robotic Interface Г creates a recognizable gap between real and virtual to open up a creative space for the user/audience to be involved between these two mediums. Mixed Robotic Interface Г uses para-fictional storytelling as a way to engage the audience with the experience and to create continues atmospheric qualities.
Abstract B138: Biochemical and cell-based activities of ectonucleotidases CD39 and CD73 using a homogenous HTS formatted platform

The success of immunotherapy treatment in oncology ushered a new modality for treating a wide variety of cancers. However, lack of effect in some patients made it imperative to identify other pathways that are exploited by cancer cells to circumvent immune surveillance, and possibly synergize immune checkpoint treatment in those cases. It has been recently recognized that adenosine levels increased significantly in the tumor microenvironment and that adenosine/adenosine receptors play a powerful role as immunosuppressant and attenuating several effector T cell functions. The two main enzymes responsible for generating adenosine in the microenvironment are the ectonucleotidases CD39 and CD73, the former utilizes both ATP and ADP and producing AMP while the latter utilizes AMP and generates adenosine. Thus, these two enzymes combined are the major source for the bulk of adenosine produced in the microenvironment. They were shown to be validated targets in oncology leading to several clinical trials that include small molecules as well as antibodies, showing positive and encouraging results in the preclinical arena. Towards the development of novel drugs to target these enzymes, we have developed a platform that can be utilized to monitor the activities of both enzymes in vitro (biochemical) as well as in cells (cell based) assays. We have developed very sensitive and homogenous assays that enabled us to monitor the activity of both enzymes and demonstrate selectivity of known small molecule inhibitors as well as selective monoclonal antibodies. This should speed up screening for novel inhibitors leading to more effective cancer therapy Citation Format: Said Goueli, kevin Hsiao. Biochemical and cell-based activities of ectonucleotidases CD39 and CD73 using a homogenous HTS formatted platform [abstract]. In: Proceedings of the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics; 2019 Oct 26-30; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Ther 2019;18(12 Suppl):Abstract nr B138. doi:10.1158/1535-7163.TARG-19-B138
Radical Recordkeeping: How Community Archives Are Changing How We Think About Records

This chapter concerns the extensive expansion of the community archives movement over the past few decades, analyzing the ways in which diverse groups of people across the world have come to recognize the task of documenting themselves as a route to collective identification. Noting that community archives are often associated with social activism, Bastian argues that this growing phenomenon is changing how we understand records and recordkeeping.
Improvement of the Effectiveness Evaluation System of Projects Implemented on the Public–Private Partnership Principles in the Complex Development of the Territory

The article presents an extended approach to the assessment of infrastructure construction projects implemented on the principles of public–private partnership (PPP). The assessment of the integral efficiency of the project based on the system-target approach is the distinctive feature of the proposed methodology. The analysis takes into account the goals, objectives and interests of all participants in the investment process. Appropriate criteria for evaluation are being developed for each of them, namely, the effectiveness of the project for the state, the private partner and the society. Integrated assessment of state efficiency involves the calculation of several criteria that is budget and social efficiency with a preliminary indicators division into groups, which allow us to give a qualitative and quantitative description of the planned project results. The assessment involves the calculation of efficiency without comparative advantage with government procurement. The private business efficiency assessment is based on the principles of investment costs profitability and payback, which are expressed in net present value, adjustments and redistribution of risks between public and private parties being taken into account. Those are risks in projects implemented on the principles of PPP in the construction industry. The integral index, presented in accordance with the additive model, is evaluated on the effectiveness criteria scale, made up using the methods of economic and mathematical analysis. The developed integral index of project efficiency, which takes into account public, social, state and private interests, will improve the evaluation accuracy and attract the attention of potential investors to PPP projects.
Chapter 19 – Gene Flow and Introgression from Domesticated Plants into their Wild Relatives*

Publisher Summary This chapter discusses the gene flow and introgression from domesticated plants into their wild relatives. Domesticated plants cannot be regarded as evolutionarily discrete from their wild relatives. Most domesticated plants mate with wild relatives somewhere in the world, and gene flow from crops may have a substantial impact on the evolution of wild populations. Planting, growing, and harvesting plants for food, fiber, fodder, pharmaceuticals, and many other uses have profound effects on the ecology and evolution of organisms in the surrounding habitats. Some of these effects may be direct and obvious. The chapter uses population genetic theory to predict the evolutionary consequences of gene flow from crops to wild plants and discusses two applied consequences of crop-to-wild gene flow—the evolution of aggressive weeds and the extinction of rare species. It suggests the ways of assessing the likelihood of hybridization, introgression, and the potential for undesirable gene flow from crops into weeds or rare species.
Settling of fixed erythrocyte suspension droplets

It is pointed out that when particles behave collectively rather than individually, the fractionation of micron-size particles on the basis of size, density, and surface characteristics by centrifugation and electrophoresis is hindered. The formation and sedimentation of droplets containing particles represent an extreme example of collective behavior and pose a major problem for these separation methods when large quantities of particles need to be fractionated. Experiments are described that measure droplet sizes and settling rates for a variety of particles and droplets. Expressions relating the particle concentration in a drop to measurable quantities of the fluids and particles are developed. The number of particles in each droplet is then estimated, together with the effective droplet density. Red blood cells from different animals fixed in glutaraldehyde provide model particle groups.
Siblings with pediatric sodium chlorite toxicity causing methemoglobinemia, renal failure and hemolytic anemia.

Abstract Introduction: Over the past decade, Miracle Mineral Solution (sodium chlorite) has been promoted as a cure-all for many conditions. Case Report: A 9-year-old boy presented with his brother after they accidentally ingested a small amount of undiluted 22.4% sodium chlorite. Symptoms included nausea, vomiting, diarrhea, and dyspnea. Oxygen saturation remained 71% despite supplemental oxygen (15L/min). The patient was noted to have dark chocolate-appearing blood, minimal urine output, diffuse pallor and cyanosis. He developed methemoglobinemia, renal failure requiring renal replacement therapy and hemolysis requiring blood transfusion. Discussion: These are the 7th and 8th reported cases of sodium chlorite toxicity by ingestion and the second and third in children. Takeaway for Physicians: Miracle Mineral Solution is a commonly purchased potentially lethal compound that can cause methemoglobinemia with respiratory failure, hemolytic anemia requiring transfusion and renal failure requiring dialysis.
Technical note: Using Johnson distributions to model trunk kinematics

As we seek to develop high fidelity human simulation models for ergonomic applications, the characterisation of the variability in human performance is needed. This technical note describes a metho...