cssi/SciSciGPT-SciSciNet huggingface dataset:
A New Thermal-Insulation and Support Concept for Extreme Environments

This paper presents an advanced thermal-insulation and structural-support concept developed at Battelle Memorial Institute. A unique, high-temperature, lightweight, metallic structure of relatively high strength is described, which is particularly suited for aerospace applications in which environmental extremes render conventional insulations inadequate. The parameters of the device, a multiple web and foil structure, are explained in detail and related to strength and insulation criteria. The relations developed are sufficiently general to allow custom designing of these two property requirements.
Arrangement: a spatial relation for describing and comparing part embeddings

A qualitative spatial relation called 'arrangement' is proposed. Given an image, the relation describes the sequence in which neighbors of each part are situated around it. The relation captures a perceptual gestalt of the image. An application of the relation to similarity retrieval in medical image databases is discussed. 'Arrangement' is closely related to directional relations and extends the notion of directional relations to parts that have complex shapes. A metric for comparing 'arrangements' is also proposed. The metric is obtained by interpreting 'arrangements' in terms of Voronoi diagrams. The metric enables robust use of the relation in real-world situations. >
Chmp 1A is a mediator of the anti-proliferative effects of all-trans retinoic acid in human pancreatic cancer cells.

Background We recently have shown that Charged multivesicular protein/Chromatin modifying protein1A (Chmp1A) functions as a tumor suppressor in human pancreatic tumor cells. Pancreatic cancer has the worst prognosis of all cancers with a dismal 5-year survival rate. Preclinical studies using ATRA for treating human pancreatic cancer suggest this compound might be useful for treatment of pancreatic cancer patients. However, the molecular mechanism by which ATRA inhibits growth of pancreatic cancer cells is not clear. The objective of our study was to investigate whether Chmp1A is involved in ATRA-mediated growth inhibition of human pancreatic tumor cells.
Race-of-Interviewer Effects in Telephone Interviews

Previous studies have found a race-of-interviewer effect on survey questions dealing with racial issues. This effect has been found in both personal interviews and on questionnaires filled out in the presence of an interviewer. This study examines whether a race-of-interviewer effect is also present in telephone interviews. The results show that a race-of-interviewer effect does occur in telephone interviews on racial questions. Patrick R. Cotter is an Assistant Professor in the Department of Political Science and the Director of Survey Research and Service in the Center for Administrative and Policy Studies at the University of Alabama. Jeffrey Cohen is an Assistant Professor in the Department of Political Science at the University of Alabama. Philip B. Coulter is Professor and Chairperson of the Department of Political Science at the University of Alabama. Public Opinion Quarterly Vol. 46:278-284 ? 1982 by The Trustees of Columbia University Published by Elsevier Science Publishing Co., Inc. 0033-362X/82/0046-278/$2.50 1 Weeks and Moore (1981) found that an ethnicity-of-interviewer effect can occur among other groups. This content downloaded from 207.46.13.124 on Wed, 22 Jun 2016 05:39:44 UTC All use subject to http://about.jstor.org/terms RACE-OF-INTERVIEWER EFFECTS 279 1981). The presence of a race-of-interviewer effect has been found in both personal interviews and on questionnaires filled out in the presence of an interviewer (Sudman and Bradbum, 1974; Campbell, 1981). In recent years, survey researchers have increasingly relied on telephone interviews to conduct their surveys, primarily because of the lower per unit costs of telephone interviews. The increasing use of this method of interviewing makes it important to determine whether a factor such as race-of-interviewer influences responses in the same manner in telephone interviews as it does in other forms of surveying. There are at least two reasons why race of interviewer may have little or no effect on responses in telephone interviews. First, in telephone interviews respondents cannot see the interviewer and thus may be unable to determine the interviewer's race. As a result, respondents may feel no need to avoid offending the interviewer. Second, even if the respondent can identify the interviewer's race, the greater physical and psychological distance between respondent and interviewer in telephone surveys may reduce any need the respondent might feel to avoid offending the interviewer. A race-of-interviewer effect may, however, be present in telephone surveys. Specifically, during the interview respondents may use verbal cues to identify the race of their interviewers. This ability, along with a sense of politeness, may result in respondents seeking to avoid offending their interviewers, despite the distance between them and the interviewers.
Corrosion of Painted Metals—A Review

Abstract Seven types of corrosion and precorrosion of painted metals are reviewed: blistering, early rusting, flash rusting, anodic undermining, filiform corrosion, cathodic delamination, and wet a...
Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress

Initiation of DNA replication at origins more than once per cell cycle results in rereplication and has been implicated in cancer. Here we use Drosophila to examine the checkpoint responses to rereplication in a developmental context. We find that increased Double-parked (Dup), the Drosophila ortholog of Cdt1, results in rereplication and DNA damage. In most cells, this rereplication triggers caspase activation and apoptotic cell death mediated by both p53-dependent and -independent pathways. Elevated Dup also caused DNA damage in endocycling cells, which switch to a G/S cycle during normal development, indicating that rereplication and the endocycling DNA reduplication program are distinct processes. Unexpectedly, however, endocycling cells do not apoptose regardless of tissue type. Our combined evidence suggests that endocycling apoptosis is repressed in part because proapoptotic gene promoters are silenced. Normal endocycling cells had DNA lesions near heterochromatin, which increased after rereplication, explaining why endocycling cells must constantly repress the genotoxic apoptotic response. Our results reveal a novel regulation of apoptosis in development and new insights into the little-understood endocycle. Similar mechanisms may operate during vertebrate development, with implications for cancer predisposition in certain tissues.
QUANTIFYING REACTIONS INFLUENCING QUALITY OF FOODS: TEXTURE, FLAVOR AND APPEARANCE1

For engineers to maintain and improve processes applied to foods, it is necessary to quantify changes in food quality as a function of process parameters. Texture, flavor and appearance (color) are sensory properties which generally have been described qualitatively and only recently have quantitative models been developed and applied. This paper reviews the application of sensory analysis for generating quantitative data on the effect of processing on texture. Generally there is a lack of data on the effect of operational parameters on texture, and, in many cases, the data which have been generated were not correctly analyzed. The requirement that engineers designing machines or processes for foods need to develop a better appreciation for the rheological properties of foods is emphasized. Finally, a systematic approach to quantifying effects of processing on texture of food must be used if food processors are to design processes based on consumer appeal.
A precomputed polynomial representation for interactive BRDF editing with global illumination

The ability to interactively edit BRDFs in their final placement within a computer graphics scene is vital to making informed choices for material properties. We significantly extend previous work on BRDF editing for static scenes (with fixed lighting and view) by developing a precomputed polynomial representation that enables interactive BRDF editing with global illumination. Unlike previous precomputation-based rendering techniques, the image is not linear in the BRDF when considering interreflections. We introduce a framework for precomputing a multibounce tensor of polynomial coefficients that encapsulates the nonlinear nature of the task. Significant reductions in complexity are achieved by leveraging the low-frequency nature of indirect light. We use a high-quality representation for the BRDFs at the first bounce from the eye and lower-frequency (often diffuse) versions for further bounces. This approximation correctly captures the general global illumination in a scene, including color-bleeding, near-field object reflections, and even caustics. We adapt Monte Carlo path tracing for precomputing the tensor of coefficients for BRDF basis functions. At runtime, the high-dimensional tensors can be reduced to a simple dot product at each pixel for rendering. We present a number of examples of editing BRDFs in complex scenes with interactive feedback rendered with global illumination.
The American Welfare State in Comparative Perspective: Reflections on Alberto Alesina and Edward L. Glaeser, Fighting Poverty in the US and Europe

Fighting Poverty in the US and Europe: A World of Difference. By Alberto Alesina and Edward L. Glaeser. Oxford: Oxford University Press, 2004. 262 pages. $55.00 clothAlberto Alesina and Edward Glaeser's recent book, Fighting Poverty in the US and Europe, exemplifies the recent incursion of economists into the domains of political science and sociology. In thinking about welfare states, economists have traditionally been interested in their effects on the distribution of income and, above all, their implications for efficiency and growth. Alesina and Glaeser instead set out to explain why “Americans are much less willing to redistribute from the rich to the poor than Europeans” (2) or, in other words, why the American welfare state is so small by comparison to European welfare states. This, then, is a book about American exceptionalism in the realm of social policy, but Alesina and Glaeser's discussion also addresses the general problem of accounting for cross-national variation in the public provision of social welfare. Their project is to provide an account of the exceptional nature of the American welfare state that is consistent with and sheds light on differences among other welfare states as well. This makes for an audacious book that deserves critical scrutiny.Jonas Pontusson is Professor of Politics at Princeton University (jpontuss@Princeton.edu). This essay was written while I was a Visiting Scholar at the Russell Sage Foundation. I am most grateful to the foundation for its support. For comments on previous drafts, I am grateful to Ira Katznelson, Mary O'Sullivan, and Kenneth Sokoloff.
Recent Thought on Egalitarianism

I. The value-judgment level, 234. — II. The consequential level, 242. — III. The causes of economic inequality, 254. — IV. The factual level, 258. — V. The determinants of egalitarianism, 261.
The percutaneous treatment of angioaccess graft complications.

Background: In the last decade, percutaneous techniques have been used with increasing frequency to treat angioaccess graft complications. The role of these procedures and their outcomes in patients on hemodialysis remains unclear. Patients and Methods: The records of all patients receiving percutaneous treatment of failed or failing angioaccess grafts were reviewed. Patient demographics, site and type of percutaneous intervention, and results of treatment were recorded. Survival curves were plotted using the Kaplan-Meier method, and differences in times to first failure between types of intervention were tested using the log rank method. Results: Grafts not requiring thrombolysis had significantly higher patency rates than those that did ( P P = 0.0004). Conclusions: Percutaneous techniques are most effective in treating failing but patent angioaccess grafts, especially those with stenoses remote from the venous anastomosis. The efficacy of percutaneous techniques diminishes significantly when used to treat grafts that have progressed to occlusion.
Getting Unstuck: Interdisciplinarity and Aging

Continuing the dialog initiated by Scheff in the March issue of Sociological Forum, we reflect on some of the challenges involved in interdisciplinary research.
Role of capillaries in determining CBF reserve: new insights using myocardial contrast echocardiography

To define the role of capillaries in the control of coronary blood flow (CBF) reserve, we developed a model of the coronary circulation and evaluated experimental data in its context. Our model com...
New technologies for studying human genetic variation.

The analysis of individual genetic variation is an important component of risk assessment. Recently a number of new technologies haye “been developed which can aid in the understanding of human variability at the genetic level. Together these techniques significantly enhance our ability to analyze the variation in the nucleotide sequence of specific genes in a population and to identify the spectrum of mutations in specific genes that are caused by a variety of agents.
Benefits of Increased Collaboration between External Stakeholders and Federal Health Care Institutions: an Evidence-Based Approach

This research project addresses the benefits of collaboration in public health between United States’ (U.S.) federal health care institutions and external stakeholders (E.S.). Employees, various heads of department from The University of Iowa Hospital & Clinics (UIHC), and residents of both Iowa and Coralville Cities in Iowa were interviewed from April to May 2015.
Open or Closed

A great philosophical tradition is at work here. You saw Professor Harrison admit to a rude barbarism compared with the rational structures, I take it, of the preceding talk by Professor Bergmann. I didn’t hear Professor Bergmann’s talk, but I’m certain it was rational, even elegant. I want rather to sound the note of crude empiricism even more evidently, to use numbers, and notions like that which up to now were somehow foreign to the cosmologist’s trade. Fortunately, they have been imported into the whole enterprise, mainly in the last decade, as the result of a set of surprises, of which the most important was surely the by now properly hallowed discovery of the microwave background.
Kelley v. Johnson and Tonsorial Tastes: The Death Knell of Substantive Due Process?

This article focuses on Kelly v. Johnson, in which the Supreme Court upheld restrictions on hair length and facial hair for policemen against claims that such restrictions violated their substantive due process rights. The decision implicitly accepted the view that the Supreme Court, and other federal courts, cannot intervene in the resolution of conflicts which arise in the daily functioning of state governments under the guise of substantive due process. It rejected the notion that federal decisions are to be made on the basis of subjective judgments by judges as to what constitutes a denial of due process. It rejected, too, any claim that misguided or ill-conceived motives or justifications will suffice to strike down state regulation as violative of due process. In short, Kelley evinced unwillingness on the part of the modern Court to invalidate state regulation on the ground of substantive due process. This article explores the Kelly case and its rationale, relationship to substantive due process precedents, and what it forebodes for the future.
Russia's Banking Sector in 2012

This paper deals with Russia's banking sector in 2012. The author focuses on relationship between banks and corporate customers, foreign transactions in the banking sector, banking regulation.
Anthropogenic noise weakens territorial response to intruder's songs

Noise pollution degrades natural acoustic conditions, potentially interfering with bird communication. However, exactly how noise impacts the ability of the signal receiver to detect and discriminate vocalizations from conspecifics remains understudied in field settings. We performed a natural experiment to determine the effect of noise pollution on the territory-defense behaviors of two emberizid sparrows exposed to carefully constructed playbacks of conspecific intruder songs. Although all birds reacted to the playbacks, response latency increased with noise levels. This suggests that noise interferes with signal reception and may indicate impaired signal discrimination. We place these results in the context of a receiver's “listening area” and the significant impact of noise pollution on this receiver-centric perceptual acoustic range. This work informs conservation efforts and provides a much needed field-based examination of the disruptive impact of noise pollution on behaviors directly related to reproduction and fitness.
Does race-ethnicity moderate the relationship between CPAP adherence and functional outcomes of sleep in US veterans with obstructive sleep apnea syndrome?

Background:Little is known about the association of race-ethnicity and the relationship of continuous positive airway pressure (CPAP) adherence with functional outcomes of sleep in American samples...
Research on Space Design Method for the Orthopaedic Robot

Based on the analysis of all kinds of spaces in the surgical environment of orthopaedic clinic,the set with constraint-activated functions is adopted to describe clinical spaces.With concepts of the robot occupancy space,the surgeon occupancy space,the surgical object space,the instrument occupancy space,the robot working space,the robot finite dexterity space,the error-sensitive coefficient,etc.,the content and the method for the orthopaedic robot space design are proposed under the surgical environment in the orthopaedic clinic.Through the space design,the finite dexterity space of the orthopaedic robot can be appropriately deployed which can improve the robot surgery precision,simplify the robot structure,and enhance the safety and reliability of the robot.Finally,the feasibility of the method is validated in the practice of space design for the bi-planar orthopaedic robot.
The implementation of enhanced measles vaccine immunity after vaccination evaluation of Qidong City

Objective:To evaluate the immune response and vaccine efficiency after measles booster shot.Methods:Multiple steps and random sampling method was used in this study.Blood samples were collected from 600 children living in the Huilong and Lushi town of Qidong city before the measles booster shot in March of year 2009.Also,540 children were se lected as a group after the measles booster shot in May of year 2009.These children livein Huilong town,Lusi town,Jinhai town,Huiping town,Haifu town and Nanyang town of Qidong city.Children in both groups were of 7 to 14 years old.Titers of serum measles IgG antibody were detected by ELISA.Positive rate and protection rate were calculated for both groups.Results:The measles IgG antibody positive rate and protection rate were 95.5% and 90.2% in the group after booster shot,while in the group before booster shot they were 92.2% and 70.1% respectively.There was statistical difference in the pro tection rate,not in the positive rate,between these two groups.Conclusion:Measles booster shot enhances immune response and vaccine efficiency.
Practice and Research of Reform in Practical Teaching System

With the reform of practical teaching in professional engineering colleges colleges,the establishment of a practical training system clled"three unified processes" includes basic skills,comprehensive skills and engineering application skills.The training system is characterized by professional teehnical training the students ability of engineering Practice skills
An Enzyme-linked Immunosorbent Assay Method for Detection of Allergens in Peanut

Peanut allergen was used to immune New Zealand big-eared rabbit to harvest antibody of 2000 000 valence,and indirect competitive enzyme-linked immunosorbent assay(ELISA) method was used in the allergens detection.The results show that there was a good linearity between 0.01 ng/mL and 100 ng/mL.The Ic50 was 34.28 ng/mL and detection limit was 0.1 ng/mL.
Development of a sensor knowledge store using a Quadtree algorithm to support autonomous vehicle path planning

This paper presents a Quadtree algorithm which is one of the several possible methods that can be used to store an unknown amount of terrain data. The Quadtree algorithm is often used for visualizing large terrain. The Triangulated Irregular Network (TIN) method has been developed recently but it is difficult to make geographical operations such as neighbor finding, searching, and updating. The purpose of this paper is to show an easy way to implement these operations.
Acute toxic nephrosis.

Acute toxic nephrosis is believed to be the best term applied to acute tubular disorders characterized by shock, acute renal insufficiency with anuria, oliguria, uremia and heart failure and their associated phenomena. Histologically there is degeneration or necrosis of the tubular epithelium which at times may be more physiologic than pathologic. Sixty-six cases are discussed emphasizing the clinical and pathologic features and therapeutics employed.
Notes on X-Efficiency and Bureaucracy

As I write I am very much aware of some of the basic difficulties one faces in attempting to analyse some aspects of the bureaucratic phenomenon. Perusal of the sociological and political science literature does not diminish the difficulties. The general problem, or set of problems, appears to be too amorphous and too large to be handled by traditional economic tools. There is no generally accepted way of abstracting some elements and ignoring others. It seems clear that almost any analysis will leave out aspects that some readers may feel are vitally important. A major handicap is the lack of a central problem focus. There are just too many questions to be asked in any attempt to understand bureaucracy. In this paper we shall limit our attention to the determinants of the internal efficiency of a bureaucratic unit where the services of the unit are given to some degree. More specifically we shall be concerned with what determines the cost per unit of service almost to the exclusion of a great many other equally interesting questions. Also we shall focus our attention on the incentives within the bureaucratic unit, and on how these incentives are generated from the outside.
Texture, aging, and superelasticity of selective laser melting fabricated Ni-rich NiTi alloys

Abstract This work studies the impact of selective laser melting (SLM) fabrication on the microstructure and texture of Ni-rich NiTi alloy. SLM NiTi samples were fabricated with a high laser power of 250 W and 1.25 m/s scanning speed. A comprehensive aging study of as-fabricated alloys is also presented to reveal the effects of aging time and temperature on transformation behavior. The shape memory properties were investigated by shape memory effect and superelasticity experiments. It was found that although SLM fabricated samples show lower strength than the initial ingot, their sharp [001] texture along the building direction improve their superelastic response substantially. In addition, it was shown that transformation temperatures can be tailored and upon thermal treatments of 350 °C-1 h and 600 °C-1.5 h, superelastic recovery up to about 5.5% can be obtained at body and room temperatures which make these alloys very promising for potential biomedical applications.
The Spectrum of Esophageal Atresia

The spectrum of esophageal atresia (EA) is commonly portrayed as comprising four basic types [1] (Fig. 6.1). This general classification satisfactorily illustrates the main configurations of EA lesions that may be encountered in affected babies. It does not convey, however, the many variations that may occur within the types nor the treatment complexities that may arise from them.
Mentoring in the ASA: A Commentary

“If we were lucky, we benefited from one or more senior colleagues who took an interest in our careers, perhaps when we were graduate students or maybe at one of our early jobs.” (“President's Corn...
How Self-Perceptions of Identity Change in Person, Role, and Social Identities Relate to Depression

This study uses a cross-sectional research design to examine how individuals perceive recent experiences of identity change in various person, role, and social identities. Specifically addressed is...
Is There a War Party? Party Change, the Left–Right Divide, and International Conflict:

Are leaders from certain parties particularly likely to engage in military conflict? This question is difficult to answer because of selection bias. For example, countries may be more likely to ele...
Linking Development to Disasters in Turkey: Moving Forward After the Marmara Earthquake

This chapter presents the disaster management reforms that have been introduced after the Marmara earthquake in Turkey in the context of a development and disaster relationship. Defining development as a process of reducing vulnerability to disasters, the chapter focuses on several reforms that were initiated after the Marmara earthquake—both in terms of organizational structure and legislation. It suggests that the government of Turkey needs to put disasters back in national-level development plans, integrate social vulnerability to the national-level strategy on earthquakes and give a voice to local actors (e.g., local governments, community based organizations) for vulnerability reduction.
Endothelial nitric oxide synthase protein distribution in endothelial cells along the coronary vascular tree

Previous investigations have compared the levels of endothelial nitric oxide synthase (eNOS) protein among different branch orders of the coronary arterial tree. In these studies, eNOS protein leve...
Fifteen Years of Peace Engineering : Models of Integration into the Senior-Design Engineering Educational Capstone Experience

Programming in the field of Peace Engineering has been a part of the fabric of our work at the University of St. Thomas for over 15 years. A Peace Engineering minor is manifested in an appropriate two semester senior design project that partners with universities, non-profits, and NGO’s in the U.S. and across the world. When coupled with a service learning abroad to collaborate in-person with a global community partner, these projects have been very impactful. Our work in this area is driven by our institutional principles of Catholic Social Teaching (CST) including social justice, solidarity, subsidiarity, sustainability, and the dignity of work. The paper will provide a summary of our 15 years of experience of success and failure in growing this core element of our engineering educational experience. We examine three models of credit-bearing student-community engagement: faculty-guided projects, collaborations with credit bearing study-abroad providers, and collaborations with onsite non-profit organizations that do not grant university credit. We conclude with our strategic objectives going forward including expansion of faculty involvement and development of specific curricular elements to support this effort.
Mulch-Derived Organic Carbon Stimulates High Denitrification Fluxes from Agricultural Ditch Sediments

Reactive N is an essential input for healthy, vibrant crop production, yet excess N is often transported off field via agricultural ditches to downstream receiving ecosystems, where it can cause negative impacts to human health, biodiversity loss, as well as eutrophication and resultant hypoxia. Denitrification, the transformation of reactive N to unreactive N gas, within agricultural ditches has potential to reduce impacts to downstream ecosystems but requires substantial organic C substrates. We used a flow-through intact core experiment to test the effects of low-cost management options including a common agricultural amendment, gypsum, and an overlying hardwood mulch layer on promoting denitrification within agricultural ditch sediments. We found significantly higher denitrification potentials in mulch (11.2 mg N-N m h) and mulch-gypsum cores (9.2 mg N-N m h) than in gypsum (1.3 mg N-N m h) or control cores (0.6 mg N-N m h). Higher denitrification rates corresponded with high dissolved organic C (DOC) fluxes within the mulch and mulch-gypsum treatments (72.8-115.2 mg m h) and were ultimately able to remove 65 to 69% of N loads. Results indicate DOC from overlying mulch additions to agricultural ditches significantly increase denitrification in intact cores and suggest that the addition of DOC sources in agricultural ditches may contribute a simple, low-cost option to reduce reactive N export and improve ecological outcomes within aquatic agroecosystems.
Thyroid, Parathyroid and Adrenal Glands

This chapter provides a practical overview of frequently used markers in the diagnosis and differential diagnosis of both common and rare neoplasms of the thyroid, parathyroid and adrenal glands, with a specific focus on papillary thyroid carcinoma and its mimickers. The chapter contains 30+ questions; each question is addressed with a table, concise note and representative pictures if applicable. In addition to the literature review, the authors have included their own experience and tested numerous antibodies reported in the literature. The most effective diagnostic panels of antibodies have been recommended for many entities, such as CK19, HBME-1, and galectin-3 being suggested as the best diagnostic panel for identifying papillary thyroid carcinoma. New markers, such as TROP-2, are discussed. Furthermore, immunophenotypes of normal thyroid tissue have been described, which tends to be neglected in literature.
Revving up the immune engine in cHL.

In this issue of Blood, Armand et al report on a clinical trial of pembrolizumab, an immunoglobulin G4 anti-programmed cell death-1 (anti-PD-1) antibody, administered to patients as consolidation or maintenance therapy after autologous stem cell transplantation (ASCT) for relapsed/refractory (RR) classical Hodgkin lymphoma (cHL).1
Pulmonary hypertension is associated with increased nonrelapse mortality after allogeneic hematopoietic cell transplantation for myelofibrosis.

Allogeneic hematopoietic cell transplantation (alloHCT) is the only curative therapy for primary myelofibrosis (MF) as well as myelofibrosis secondary to other myeloproliferative neoplasms (MPN). Pulmonary hypertension (PH) is a known complication of MF and may occur in up to 50% of such patients. PH (defined as a mean pulmonary artery pressure ≥25 mmHg at rest) can eventually lead to right heart failure and may be associated with complications after alloHCT. We examined the association of PH with alloHCT outcome in patients with MF associated with MPN. Pre- and post-HCT echocardiograms were reviewed to estimate the peak pulmonary artery systolic pressure (PASP). Median PASP was 37.0 mmHg (range: 16.0-57.9) prior to HCT with 37 of 65 patients (57%) studied. With median follow-up of 35.0 months (range: 3.3–119.4) PH was significantly associated with inferior OS (58.9% vs. 88.8%, P = 0.025), primarily due to increased NRM (21.6% vs. 7.1%, P = 0.007). The majority of the deaths (8 of 14) in patients with PH occurred within 100 days after HCT. In patients with an available post-HCT echocardiogram (n = 33), the median PASP was 30 mmHg (range: 5.0–56.2); eight patients (24%) had persistent PH. Compared with pre-HCT values, PASP was significantly reduced after HCT (p < 0.001). We conclude that PH is associated with inferior survival due to the increased NRM in patients with MF undergoing alloHCT. PH appears at least partially reversible after successful alloHCT. PH should be considered a risk factor for early mortality after alloHCT and surveillance of pulmonary artery pressure in MF patients being considered for alloHCT may be useful.
Field-induced magnetic transition and spin fluctuations in the quantum spin-liquid candidate CsYbSe 2

Two-dimensional triangular-lattice materials with spin-1/2 are perfect platforms for investigating quantum frustrated physics with spin fluctuations. Here we report the structure, magnetization, heat capacity, and inelastic neutron scattering (INS) results on cesium ytterbium diselenide, ${\mathrm{CsYbSe}}_{2}$. There is no long-range magnetic order down to 0.4 K at zero field. The temperature-dependent magnetization, $M(T)$, reveals an easy-plane magnetic anisotropy. A maximum is found in $M(T)$ around $T\ensuremath{\approx}1.5$ K when magnetic field $H$ is applied in the $ab$ plane, indicating the short-range interaction. The low-temperature isothermal magnetization $M(H)$ shows a one-third plateau of the estimated saturation moment, which is characteristic of a two-dimensional (2D) frustrated triangular lattice. Heat capacity shows field-induced long-range magnetic order for both $H||c$ and $H||ab$ directions. The broad peak in heat capacity and highly damped INS magnetic excitation at $T=2$ K suggests strong spin fluctuations. The dispersive in-plane INS, centered at the (1/3 1/3 0) point, and the absence of dispersion along the $c$ direction suggest ${120}^{\ensuremath{\circ}}$ noncollinear 2D-like spin correlations. All these results indicate that the two-dimensional frustrated material ${\mathrm{CsYbSe}}_{2}$ can be in proximity to the triangular-lattice quantum spin liquid. We propose an experimental low-temperature $H\text{\ensuremath{-}}T$ phase diagram for ${\mathrm{CsYbSe}}_{2}$.
Recruiting women into your computing major: conference tutorial

Active recruiting of diverse students works. By personally reaching out to women and minority students, and their influencers, with messages tailored to appeal to them, faculty can attract more and better students to the computing major. This session provides a quick overview of what research tells us about recruiting, and encourages participants to adopt a coordinated approach that focuses on high yield in the short term, leverages available resources, and makes use of evaluation for concentrating effort on the most productive activities. Professional quality NCWIT (National Center for Women & IT) materials, including a recruiting workbook, will be provided to participants in this session.
Experiments and Agent Based Models of Zooplankton Movement within Complex Flow Environments.

The movement of plankton is often dictated by local flow patterns, particularly during storms and in environments with strong flows. Reefs, macrophyte beds, and other immersed structures can provide shelter against washout and drastically alter the distributions of plankton as these structures redirect and slow the flows through them. Advection–diffusion and agent-based models are often used to describe the movement of plankton within marine and fresh water environments and across multiple scales. Experimental validation of such models of plankton movement within complex flow environments is challenging because of the difference in both time and spatial scales. Organisms on the scale of 1 mm or less swim by beating their appendages on the order of 1 Hz and are advected meters to kilometers over days, weeks, and months. One approach to study this challenging multiscale problem is to insert actively moving agents within a background flow field. Open source tools to implement this sort of approach are, however, limited. In this paper, we combine experiments and computational fluid dynamics with a newly developed agent-based modeling platform to quantify plankton movement at the scale of tens of centimeters. We use Artemia spp., or brine shrimp, as a model organism given their availability and ease of culturing. The distribution of brine shrimp over time was recorded in a flow tank with simplified physical models of macrophytes. These simplified macrophyte models were 3D-printed arrays of cylinders of varying heights and densities. Artemia nauplii were injected within these arrays, and their distributions over time were recorded with video. The detailed three-dimensional flow fields were quantified using computational fluid dynamics and validated experimentally with particle image velocimetry. To better quantify plankton distributions, we developed an agent-based modeling framework, Planktos, to simulate the movement of plankton immersed within such flow fields. The spatially and temporally varying Artemia distributions were compared across models of varying heights and densities for both the experiments and the agent-based models. The results show that increasing the density of the macrophyte bed drastically increases the average time it takes the plankton to be swept downstream. The height of the macrophyte bed had less of an effect. These effects were easily observed in both experimental studies and in the agent-based simulations.
Effective reviewing for conceptual journal submissions

Peer reviewed academic journals, like AMS Review, live and die by their ability to obtain high quality reviews of submitted manuscripts. However, academics are increasingly pressed for time, needing to publish their research, teach their classes, and provide service to their Department, Faculty/College and University to support their careers in terms of retention, tenure, and promotion. Amidst these responsibilities, as a service to the Academy, academics also are expected to provide reviews of manuscripts in order to move the intellectual trajectory of the domain forward. High quality reviewing, though, takes cognitive energy and is time consuming, which then interferes with other academic responsibilities. For these reasons, editors of peer-reviewed academic journals are finding it more and more difficult to obtain a sufficient number of high-quality reviews to make good decisions about submissions in a timely manner. The purpose of this article is to help all reviewers, but especially those reviewing conceptual articles, provide a high-quality review. Specifically, this article first defines what constitutes a “high quality review,” and suggests how reviewing can aid an academic’s own research, writing and career. It then defines the behaviors needed for effective reviewing for all manuscripts, termed the 5 R’s: roles, responsibilities, responses, reactions, and respect. It then provides a reviewing template for conceptual articles, given the special difficulties of peer reviewing such articles, and closes with a few additional pieces of advice to help with being efficient in reviewing, while being effective.
Long Non-Coding RNA CRNDE Regulates Angiogenesis in Hepatoblastoma by Targeting the MiR-203/VEGFA Axis.

Objective MiR-203 has been shown to participate in multiple malignancies, but the role of miR-203 in hepatoblastoma (HB) remains unclear. The aim of our study was to investigate the effects of miR-203 in HB. Methods A total of 15 pairs of HB tissues and para-tumour normal tissues were collected for the experiments. RT-qPCR and Western blotting were performed to detect the expression of CRNDE, miR-203, and VEGFA at the mRNA and/or protein levels, respectively. A dual luciferase assay verified the target relationship between miR-203 and the 3'UTR of VEGFA as well as miR-203 and CRNDE. In addition, MTT, wound healing, and tube formation assays were performed to assess the effects of miR-203, VEGFA, and CRNDE on cell proliferation, migration, and angiogenesis, respectively. Results Our data revealed that miR-203 expression was decreased in HB tissues, while long non-coding RNA (lncRNA) CRNDE expression was increased. The dysregulation of miR-203 and CRNDE was closely related to tumour size and stage. Moreover, overexpression of miR-203 inhibited angiogenesis. A dual luciferase assay verified that VEGFA is a direct target of miR-203 and that CRNDE binds to miR-203. Furthermore, our results showed that miR-203 suppressed cell viability, migration, and angiogenesis by regulating VEGFA expression. Additionally, it was confirmed that CRNDE promoted angiogenesis by negatively regulating miR-203 expression. Conclusion lncRNA CRNDE targets the miR-203/VEGFA axis and promotes angiogenesis in HB. These results provide insight into the underlying mechanisms of HB and indicate that CRNDE and miR-203 might be potential targets for HB therapy.
Cache-Out: Leaking Cache Memory Using Hardware Trojan

Data leakage is an important security concern in current systems. Existing data leakage prevention techniques assume that the underlying hardware platform is secure and free from tampering. In this work, we present Cache-Out, a class of system attacks involving hardware compromised with a Trojan embedded in the CPU. We assume that a memory Trojan trigger is present in L1 d-cache and gets activated if one particular address of L1 d-cache is hammered with a particular data pattern for a certain number of times. Once the Trojan is triggered, accessing another address delivers payloads, such as, read disturb, write disturb, retention failure, and information leakage. We mainly exploit the advanced circuit features employed in the peripherals of nanometer cache memories, such as wordline underdrive (WLUD) (prevents read disturb) and negative bitline (NBL) (assists write) for static RAM (SRAM) to deliver the payloads. Simulation indicates that WLUD and NBL manipulation can inject read and write failures, respectively. We also show that WLUD activation during write operation can inject write failure. Furthermore, NBL along with column multiplexing can also be leveraged to steal data. We validated Cache-Out using GEM5 architectural simulator. We propose L1 address obfuscation, read/write verification, scrambling error correcting code (ECC) bits, and trusted ECC as countermeasures. Results indicate that read/write verification incurs $7.56~\mu \text{m}~^{\mathrm{ 2}}$ of area and $0.1~\mu \text{W}/91.3~\mu \text{W}$ of static/dynamic power in 22-nm technology for a 64-bit word size.
The Moderating Effect of Gender on Expectations and Threats Related to Relationship Help-Seeking

Couples often wait until they are on the brink of divorce before seeking professional help for their relationship. Why do couples wait so long? Current research cannot provide an adequate answer to...
The Origins of PTSD: Psychodynamic Trauma and the Human Stress Response

There exist two well-developed and sometimes conflicting theories as to the cause of PTSD. Working from Freud’s theories of psychodynamics, the psychological community describes the origin of PTSD and other psychiatric disorders as a maladaptive response to irreconcilable trauma with focus on the neurocognitive processes of emotion and feeling. This theoretical perspective lies behind the psychoactive medications used to treat PTSD, as well as giving justification for the cognitive behavioral therapies that have proven so useful in treating its symptoms. An alternative approach to PTSD has been developed by physiologists and physicians who have focused on the chemistry and neuroanatomy of the human stress response. Their focus has been on the neuroendocrine chemistry of stress and the neuroanatomic systems involved in the neuro-processing of fear. This approach has led to the use of medications such as antihypertensives that block catecholamines in treating both nightmares and PTSD. Despite a lack of evidence that might tie these two approaches together, neuroscientists and clinicians routinely attempt to conflate these two very different approaches to diagnosing and treating PTSD.
A Preliminary Examination of Shoulder Joint Function Following Shoulder Complex Training and In-Season Play in Youth Baseball Players

Background: As shoulder care continues to be a concern for youth baseball players, coaches, parents, researchers and clinicians, shoulder complex care should remain a point of emphasis especially for in overhead athletes. The impact of throwing volume and shoulder care is important for us to understand. Objective: The purpose was to examine the changes in shoulder complex function during a playing season combined with shoulder complex training in young male baseball players. Methods: Eleven male baseball players (11-15 y/o) served as subjects. Pre-testing included shoulder joint internal/external rotation peak torque and average work as measured with isokinetic dynamometry (Biodex System 4Pro). Training over the 18-week project duration was Crossover Symmetry “Activation” and “Strength” protocols completed per manufacturer recommendations. Adherence was tracked via a weekly email sent to the subject’s guardian to self-report completed training. Post-testing was conducted at the conclusion of the 18th week. Paired sample t-tests compared pre-test and post-test mean differences for peak torque and average power (p<0.05). Results: All-subject average for training was 54 sessions over the 18 weeks. Estimated number of throws completed during practice and games over the 18 weeks was 8,400. For both testing speeds and for both internal and external shoulder joint rotation, peak torque increases ranged from ~50% for external rotation at 60 deg/s up to ~200% for internal rotation at 120 deg/s. Statistical differences (p<0.001) were noted between all pre-test and post-test internal and external rotation peak torque values. For both testing speeds and for both internal and external shoulder joint rotation, average power increases ranged from ~38% at 60 deg/s for external rotation up to ~200% at 120 deg/s for internal rotation. Statistical differences (p<0.005) were noted between all pre-test and post-test internal and external rotation average power values. Conclusions: Substantial increases in shoulder joint rotation peak torques and power were seen across the 18-week study duration. As this was a preliminary investigation, we have yet to discern if these increases are due to the shoulder complex training or volume of throwing that was completed.
A Finite Difference Method on Irregular Grids with Local Second Order Ghost Point Extension for Solving Maxwell's Equations Around Curved PEC Objects.

A new finite difference method on irregular, locally perturbed rectangular grids has been developed for solving electromagnetic waves around curved perfect electric conductors (PEC). This method incorporates the back and forth error compensation and correction method (BFECC) and level set method to achieve convenience and higher order of accuracy at complicated PEC boundaries. A PDE-based local second order ghost cell extension technique is developed based on the level set framework in order to compute the boundary value to first order accuracy (cumulatively), and then BFECC is applied to further improve the accuracy while increasing the CFL number. Numerical experiments are conducted to validate the properties of the method.