cssi/SciSciGPT-SciSciNet huggingface dataset:
Multiple Comparisons of Parametric Models in Longitudinal Studies

In longitudinal analysis, interest lies often in comparing parametric models over time. For example, if the trend over time is linear, commonly a test is performed to evaluate whether the rate of change in the mean response is the same for all treatment groups. For parametric models, treatment profiles can easily be compared using confidence bands. The authors propose simultaneous confidence bands and discuss two methods of calculating the associated critical point for comparing several parametric models over time. This issue has never been addressed before in the context of longitudinal studies. An example illustrates the proposed method.
BarCampOrlando 2009: a model for libraries?

Purpose – The purpose of this paper is to report on the BarCampOrlando 2009 conference and to explore the model of an “unconference.”Design/Methodology/Approach – This is a conference report.Findings – BarCamp gatherings bring together people passionate about technology with no set agenda. The unconference model holds possibility for the library world. Originality/Value – The paper reports on business marketing, design, and mission topics presented at the BarCampOrlando conference that are applicable to libraries. The “unconference” model embodied at BarCamp and its potential implementation in the library world is discussed.
Detection of Regional Air Pollution Episodes Utilizing Satellite Digital Data in the Visual Range

A comparative analysis of satellite digital data in the visual range and ground-based aerosol measurements was carried out for July 21 and 22, 1978, representing a significant pollution episode based on low surface visibility and high sulfate levels. Quantitative information on total aerosol loading derived from the satellite digitized data using an atmospheric radiative transfer model agrees well with the results obtained from the ground-based measurements. It is also shown that the extent and transport of the haze pattern can be monitored from the satellite data over the period of maximum intensity of the episode. The model simulation demonstrates the potential of utilizing satellites to monitor both the magnitude and areal extent of pollution episodes.
Application of multiple decision trees for condition monitoring in induction motors

Induction machines (IMs) play a pivotal role in industry and there is a strong demand for their reliable and safe operation. IMs are susceptible to problems such as stator current imbalance and broken bars, usually detected when the equipment is already broken, and sometimes after irreversible damage has occurred. Condition monitoring can significantly reduce maintenance costs and the risk of unexpected failures through the early detection of potential risks. Several techniques are used to classify the condition of machines. This paper presents a new case study on the application of multiple decision trees in the on-line condition monitoring of induction motors. Some advantages can be seen, such as the improved performance of classification systems, in addition to the capacity to explain examples. The database was developed through a simplified mathematical model of the machine, considering the effects caused by asymmetries in the phase impedances of motors. A comparative analysis is performed for individual running (based on the neural networks, k-Nearest neighbor and Naive Bayes) and a multi-classifier (based on the Bagging and Adaboost) approaches. Results demonstrate that the multi-classifier systems obtain better results than those of the individual experiments.
Technology, transport, globalization and the nutrition transition food policy

Abstract Diet and activity have been affected by the rapid worldwide shifts in technological innovations reducing energy expenditures during leisure, transportation, and work; globalized modern food processing, marketing and distribution techniques; global mass media. The increases occur increasingly in rural areas on all continents. The resultant global increase in obesity increasingly is shifting the burden of obesity to the poor. While few direct linkages between globalization of trade in goods, services, and technology can be directly linked to diet and activity, a strong case exists for globalization’s role as a key underlying force behind this stage of the nutrition transition.
The Class Analysis of Poverty: A Response to Tony Novak

In responding to Tony Novak's criticisms of his earlier article "The Class Analysis of Poverty," the author makes four principle points. First, contrary to Novak's views, a class analysis to poverty should define poverty in terms of both income-poverty and asset-poverty. Second, while Novak is correct that the term "underclass" often has a pejorative meaning, it remains an important concept for identifying segments of the population that are deeply oppressed economically, but not exploited. Third, the concepts of class analysis must be elaborated at a variety of levels of abstraction, not simply the highest level of the pure "mode of production," as is implied by Novak's arguments. Finally, class analysis must acknowledge and conceptualize the specific forms of complexity of contemporary class structures, which is impossible if it restricts its class concepts to a simple polarized notion.
Nomograms Predicting Response to Therapy and Outcomes After Bladder-Preserving Trimodality Therapy for Muscle-Invasive Bladder Cancer

Purpose Selective bladder preservation by use of trimodality therapy is an established management strategy for muscle-invasive bladder cancer. Individual disease features have been associated with response to therapy, likelihood of bladder preservation, and disease-free survival. We developed prognostic nomograms to predict the complete response rate, disease-specific survival, and likelihood of remaining free of recurrent bladder cancer or cystectomy. Methods and Materials From 1986 to 2009, 325 patients were managed with selective bladder preservation at Massachusetts General Hospital (MGH) and had complete data adequate for nomogram development. Treatment consisted of a transurethral resection of bladder tumor followed by split-course chemoradiation. Patients with a complete response at midtreatment cystoscopic assessment completed radiation, whereas those with a lesser response underwent a prompt cystectomy. Prognostic nomograms were constructed predicting complete response (CR), disease-specific survival (DSS), and bladder-intact disease-free survival (BI-DFS). BI-DFS was defined as the absence of local invasive or regional recurrence, distant metastasis, bladder cancer-related death, or radical cystectomy. Results The final nomograms included information on clinical T stage, presence of hydronephrosis, whether a visibly complete transurethral resection of bladder tumor was performed, age, sex, and tumor grade. The predictive accuracy of these nomograms was assessed. For complete response, the area under the receiving operating characteristic curve was 0.69. The Harrell concordance index was 0.61 for both DSS and BI-DFS. Conclusions Our nomograms allow individualized estimates of complete response, DSS, and BI-DFS. They may assist patients and clinicians making important treatment decisions.
Aerospace Application of Atmospheric Rendezvous

This paper studies the feasibility of the use of an atmospheric rendezvous concept to increase the efficiency and flexibility of space transportation systems. In this concept the second stage of a recoverable orbital launch vehicle or hypersonic transport would be built without wings, landing gear, or subsonic flight propulsion, and would be received in an atmospheric rendezvous by a carrier vehicle at the terminal point of flight for subsequent ferry to a landing site. Significant possibilities for weight improvement are shown and the attractiveness of a subsonic form of atmospheric rendezvous in either a towing or docking mode is illustrated.
7T MRI detects deterioration in subchondral bone microarchitecture in subjects with mild knee osteoarthritis as compared with healthy controls

Purpose To determine how subchondral bone microarchitecture is altered in patients with mild knee osteoarthritis. Materials and Methods This study had Institutional Review Board approval. We recruited 24 subjects with mild radiographic knee osteoarthritis and 16 healthy controls. The distal femur was scanned at 7T using a high-resolution 3D FLASH sequence. We applied digital topological analysis to assess bone volume fraction, markers of trabecular number (skeleton density), trabecular network osteoclastic resorption (erosion index), plate-like structure (surface), rod-like structure (curve), and plate-to-rod ratio (surface-curve ratio). We used two-tailed t-tests to compare differences between osteoarthritis subjects and controls. Results 7T magnetic resonance imaging (MRI) detected deterioration in subchondral bone microarchitecture in both medial and lateral femoral condyles in osteoarthritis subjects as compared with controls. This was manifested by lower bone volume fraction (−1.03% to −5.43%, P < 0.04), higher erosion index (+8.49 to +22.76%, P < 0.04), lower surface number (−2.31% to −9.63%, P < 0.007), higher curve number (+6.85% to +16.93%, P < 0.03), and lower plate-to-rod ratio (−7.92% to −21.71%, P < 0.05). Conclusion The results provide further support for the concept that poor subchondral bone quality is associated with osteoarthritis and may serve as a potential therapeutic target for osteoarthritis interventions. J. Magn. Reson. Imaging 2015;41:1311–1317. © 2014 Wiley Periodicals, Inc.
Defining a market: market mitigation by theory versus convenience

The events of the California energy crisis of 2000 quickly led to complaints being filed at the Federal Energy Regulatory Commission (FERC) and subsequent prolonged litigation over prices and profits. The simplicity (perhaps excessively so) of the commission's procedure for determining mitigated market prices rapidly fell prey to the litigation proceedings and quickly lost any connection it might initially have had to either power engineering or economic reality. This paper examines selected aspects of the California market mitigation process, comparing theoretically desired outcomes of market mitigation with the actual process in California. Results are presented that demonstrate the distortion of such basic steps as market definition and the identification of full incremental costs. The mitigation results and the lessons learned by the various groups involved are analyzed both with respect to engineering and economic realities and with respect to political exigencies. The results in California are then placed in the broader context of a likely end phase of electric industry restructuring.
SHape REtrieval contest 2008: Classification of watertight models

This track focuses on 3D shape classification, i.e. the assignment of a query object to one of the classes in a database. A total amount of 646 watertight models have been classified, and released as training, testing and query data. Three different levels of categorization have been taken into account, from coarse to fine.
Course of Violence in Patients With Schizophrenia: Relationship to Clinical Symptoms

To understand the heterogeneity of violent behaviors in patients with schizophrenia, one must consider underlying clinical symptoms of the illness and their change over time. The purpose of this study was to examine persistence and resolution of violence in relation to psychotic symptoms, ward behaviors, and neurological impairment. Psychiatric symptoms and ward behaviors were assessed in violent inpatients with schizophrenia or schizoaffective disorder and in nonviolent controls on entry into the study. Patients were followed for 4 weeks; those who showed resolution of assaults over this time were classified as transiently violent, and those who remained assaultive were categorized as persistently violent. At the end of the 4 weeks, psychiatric symptoms, ward behaviors, and neurological impairment were assessed. Overall, the two violent groups presented with more severe psychiatric symptoms and were judged to be more irritable than the nonviolent control subjects, but the transiently violent patients showed improvement in symptoms over time. At the end of 4 weeks, the persistently violent patients had evidence of more severe neurological impairment, hostility, suspiciousness, and irritability than the other two groups. Canonical discriminant analyses identified two significant dimensions differentiated the groups. The first, characterized by positive psychotic symptoms, differentiated the violent patients from the control subjects; the second, characterized by neurological impairment and high endpoint score for negative symptoms, differentiated the transiently from the persistently violent patients. Identification of certain symptoms associated with different forms of violence has important implications for the prediction and differential treatment of violent behavior in patients with schizophrenia.
Assessment of compliance with US Public Health Service Clinical Practice Guideline for tobacco by primary care physicians

The US Public Health Service Clinical Practice Guideline Treating Tobacco Use and Dependence: 2008 Update established an expanded standard of care, calling on physicians to consistently identify their patients who use tobacco and treat them using counseling and medication. To assess compliance, we examined the extent to which physicians self-report following four of the five components of the 5A model: Ask about tobacco use, Advise patients who use tobacco to quit, Assist the patient in making a quit attempt, and Arrange for follow-up care. We used data from a Web-based panel survey administered to a convenience sample of 1,253 primary care providers (family/general practitioners, internists, and obstetrician/gynecologists). We found that 97.1% of the providers reported that they consistently Asked and documented tobacco use, while 98.6% reported that they consistently Advised their patients to quit using tobacco. Among the family/general practitioners and internists, 98.3% recommended “any” (medication, counseling, counseling and medication, telephone quitline) smoking cessation strategies (Assist). Among all providers, 48.0% reported that they consistently scheduled a follow-up visit (Arrange). This study revealed that most primary care physicians reported that they Ask their patients about tobacco use, Advise them to quit, and Assist them in making a quit attempt, but only half reported that they Arrange a follow-up visit. Tobacco use screening and intervention are among the most effective clinical preventive services; thus, efforts to educate, encourage, and support primary care physicians to provide evidence-based treatments to their patients should be continued.
MF59™ as a vaccine adjuvant: a review of safety and immunogenicity

Approximately 70 years passed between the licensing of alum salts as vaccine adjuvants and that of MF59™ MF59, an oil-in-water emulsion, is currently licensed for use in the elderly as an adjuvant in seasonal influenza vaccines. Its mechanism of action is not fully understood, but enhancement of the interaction between the antigen and the dendritic cell seems to be involved. When used with seasonal influenza vaccines, an increase occurs in the hemagglutination inhibition antibody titers against some, but not all, seasonal vaccine influenza strains. The adjuvant effect is more pronounced when MF59 is combined with novel influenza antigens such as H9 and H5. The use of the adjuvant is associated with an increase in the frequency of local and systemic early post-vaccine adverse events (3-7 days), but no increase in adverse events was observed thereafter. Currently, MF59 is under evaluation as an adjuvant with other antigens such as pandemic influenza antigens and cytomegalovirus antigens.
Relative subjective count and assessment of interruptive technologies applied to mobile monitoring of stress

A variety of technologies-from agents designed to assist or encourage you, to context-based messaging services-have the opportunity to interrupt you many times throughout the day. One of the challenges with designing new highly interruptive technologies is how to objectively assess their influence on human experience. This paper presents an assessment of a new mobile system that interrupts the wearer to support self-monitoring of stress. We utilize a diverse set of assessment techniques, including a newly proposed measure, relative subjective count, which compares the difference in perceived number of interruptions to actual number of interruptions. This measure, together with direct and indirect subjective reports, and a behavioral choice, is used to evaluate an empathetic version of the mobile system vs. a non-empathetic version. We found that post-experience direct questionnaire assessments such as ''how stressful has using the system been?'' do not significantly distinguish user experiences with the two systems; however, the new measure of relative subjective count, the behavioral choice, and another indirect questioning strategy, do point toward a preference for the empathetic system.
Use of ground-penetrating radar for asphalt thickness determination

A computer program, called TERRA (Thickness Evaluation of Roads by RAdar) was recently developed for estimating pavement layer thicknesses from ground penetrating radar (GPR) data. This program incorporates decision criteria for automated detection of layer interfaces, computation of layer thicknesses and a segmentation algorithm for delineating segments based on layer thicknesses. The Florida Department of Transportation (FDOT) initiated the present field study for an initial assessment of TERRA. Radar and core data were collected from several flexible pavement sections of Florida's roadway system. These sites were selected to represent the present Florida in-place mixes (Superpave and Marshall mixtures) and different asphalt layer thicknesses, which varied from approximately 50 to 300 mm (2 to 12 in). Radar data were collected at both highway speeds and in stationary mode. This paper presents a description of the data collection effort as well as the subsequent analysis and findings.
What is the appropriate duration of dual antiplatelet therapy

Healthcare providers often are faced with the challenge of determining an appropriate length of dual antiplatelet therapy (DAPT) for patients who have had percutaneous coronary intervention and stent placement. This is an especially challenging clinical decision for patients with drug-eluting stents, as several studies show different results when assessing risk and benefit.
Structural damping and self-sensing actuation in Terfenol-D magnetostrictive materials

Terfenol-D magnetostrictive material has been used for actuation but rarely for "reverse" transduction from mechanical to electrical energy. A Terfenol-D transducer produces intense magnetic fields when compressed which are converted into electrical energy by a surrounding coil. This electrical energy can be dissipated in a coil shunt resistor to increase structural damping. During motion, the transducer coil produces a voltage that is proportional to velocity. High Terfenol-D energy density produces high modal damping, as well as high velocity sensor resolution. Terfenol-D has several benefits including low mass, stable properties, lack of fatigue, low operating voltages, and low temperature sensitivity. Models of transducer damping and velocity sensing performance are developed from Terfenol-D properties and transducer geometry. The models are validated by experiments showing modal loss factors up to 0.22, and velocity scale factors of 183 V/(m/s). Velocity sensing is demonstrated simultaneously with actuation, and during damping operation. The feasibility of Terfenol-D transducers for passive damping and selfsensing actuation is supported.
Hygiene quality of the rural drinking water in zhengzhou city during 2008-2012

Objective To realize hygiene quality of the rural drinking water after rural drinking water security projects had been carried into execution to take countermeasures and study management methods.Methods 3 660 sites of rural drinking water security projects were selected to monitor different types of water sources for rural water plants between different periods during 2008-2012,analyze the monitoring meta and make assessment.19 monitoring indexes were detected including organoleptic,physical,chemical,and microbial parameters.Results Qualified rate of total numbers of the rural drinking water was low,there were no significant difference between treated water and the tap water(χ2=2.12,P﹥0.05),and both had significant difference between wet and dry period(χ2=8.34,P﹤0.01),in the dry period,water quality is better(χ2=5.25,P﹤0.05);the major factor affecting the water quality is microorganism,which leads to a low qualified rate.Conclusion The rural drinking water quality of different periods,after taking rural drinking water security projects is different,the rural drinking water quality exists hygiene safety harm.We should operate assessment as rural drinking water security projects start.It is suggested that government increase investment,enhance training,strengthen supervision to ensure the hygiene quality of drinking water.
MO-DE-204-04: Dose Optimization in CT: Trends and Motivation in the US

The main topic of the session is to show how dose optimization is being implemented in various regions of the world, including Europe, Australia, North America and other regions. A multi-national study conducted under International Atomic Energy Agency (IAEA) across more than 50 less resourced countries gave insight into patient radiation doses and safety practices in CT, mammography, radiography and interventional procedures, both for children and adults. An important outcome was the capability development on dose assessment and management. An overview of recent European projects related to CT radiation dose and optimization both to adults and children will be presented. Existing data on DRLs together with a European methodology proposed on establishing and using DRLs for paediatric radiodiagnostic imaging and interventional radiology practices will be shown. Compared with much of Europe at least, many Australian imaging practices are relatively new to the task of diagnostic imaging dose optimisation. In 2008 the Australian Government prescribed a requirement to periodically compare patient radiation doses with diagnostic reference levels (DRLs), where DRLs have been established. Until recently, Australia had only established DRLs for computed tomography (CT). Regardless, both professional society and individual efforts to improved data collection and develop optimisation strategies across a range of modalities continues. Progress in this field, principally with respect to CT and interventional fluoroscopy will be presented. In the US, dose reduction and optimization efforts for computed tomography have been promoted and mandated by several organizations and accrediting entities. This presentation will cover the general motivation, implementation, and implications of such efforts. Learning Objectives: 1.Understand importance of the dose optimization in Diagnostic Radiology. 2.See how this goal is achieved in different regions of the World. 3.Learn about the global trend in the dose optimization and future prospectives. M. Rehani, The work was a part of the work of IAEA where I was an employee and IAEA is a United Nations organization
Control-system simulation on small personal-computer workstations

New software with efficient utilization of the 8067/80287 math co-processor permits remarkably powerful control-system simulations on small personal computers (IBM PC/XT/AT and. compatibles). The n...
“Dude, Where’s My Bard?”

This work takes as its starting point the strange intertextual space Shakespeare has come to occupy in contemporary America: His works are read in schools, used as raw material for film, television, and stage adaptations, re-created as graphic novels, referenced in commercials and advertisements, and used as a framework to understand adolescent girls, contemporary cultural and social conflicts, and business practices. We no longer have “Shakespeare,” but rather “Shakespeares.” As Frederic Jameson argues in Postmodernism, or the Cultural Logic of Late Capitalism, the border has broken down between high art and mass culture: commercial culture is incorporated directly into postmodern art and high culture has become a commodity. What might at first glance be dismissed as immature, trendy, silly, or insignificant is actually indicative of both Shakespeare’s place in contemporary culture as well as indicative of the dominance of youth culture, even in the face of the “universality” and classical status of Shakespeare.
Breaking the Cycle of Unrestrained Presidential National Security Power

As a number of scholars have argued, constitutional and statutory limits have failed to constrain presidential national security power after 9/11 (Fisher 2012b; Pious 2011; Glennon 2015; Edelson 2016). Both the George W. Bush and Obama administrations have found ways around legal limitations on presidential power, while a generally acquiescent Congress has often failed to act and Supreme Court decisions aimed at setting limits have failed to have an effect.If this diagnosis is right – that presidential power has broken free of the rule of law and must be reined in – then what is the prescription? How is this problem to be resolved, and how can a balance be struck between the need for sufficient presidential power to defend national security and the need for meaningful legal restraints on power? This paper will consider specific proposals aimed at achieving these goals. I will consider the role various actors can play: (a) members of Congress, (b) the press, (c) the public, (d) scholars, (e) executive branch lawyers and (f) the courts. My methodological approach is qualitative, based on an analysis of specific actions taken by past presidents, other executive branch actors, legislators, and judges. I use primary sources, including executive orders, Department of Justice memoranda, and court decisions. I also draw on relevant scholarship in the area, including the sources mentioned above. For those interested in finding ways to limit presidential power, recent history provides hopeful examples, including (1) actions members of Congress took in August 2013 to prevent President Obama from acting unilaterally against the Assad regime; (2) actions by some executive branch lawyers in both the George W. Bush (Jack Goldsmith on warrantless surveillance) and Obama administrations (Caroline Krass on military action in Libya after the War Powers Resolution window closed) and (3) legislative changes to bulk metadata collection following the Snowden revelations regarding surveillance. Recent history also provides cautionary tales, or examples to be avoided — for example, Congress’s failure to act regarding ISIS, Harold Koh’s definition of hostilities under the War Powers Resolution, and John Yoo’s memos advancing the idea of an unconstrained unitary executive.With a new president taking office next year, this is a useful moment to consider what actions can be taken to break the cycle of unrestrained presidential power. This paper proposes a number of specific ideas designed to achieve this goal.
Distinguishing subpopulations of marijuana users with latent profile analysis

Abstract Background Although marijuana is the most commonly used illicit drug in the United States, little is known about the effects of typical marijuana use patterns and whether there are distinct subgroups of marijuana users. Methods The present study used latent profile analysis to determine the number of distinct subgroups of marijuana users in a large sample of college students (n = 2129 past month marijuana users across 11 universities). We also examined how these distinct groups differ on several putative risk/protective factors (e.g., personality traits, perceptions of marijuana, and motives for using marijuana). Results Using the Lo-Mendell-Rubin Likelihood Ratio Test, we identified four latent classes with the largest class consisting of infrequent marijuana users, and three other classes demonstrating increasingly frequent use and more negative consequences with the most severe class being the smallest class. We found the largest between-class differences (i.e., distinctions across classes) to be on identification with being a marijuana user and use of protective behavioral strategies (PBS), such that the heavier user classes showed higher identification with marijuana users and lower use of PBS. Conclusions Our findings demonstrate that college student marijuana users are a heterogeneous group with different profiles of risk/protective factors and that those who use marijuana a few times per month are different from those who are near-daily or daily users. Our findings also serve as a call to action for the field to consider examining identification with being a marijuana user and the use of PBS in future marijuana studies.
AoA assisted localization for underwater Ad-Hoc sensor networks

In this paper, We propose angle of arrival (AoA) assisted localization scheme for underwater Ad-Hoc sensor networks in 2-D and 3-D. This scheme estimates distances from sensor nodes to anchor nodes via multi-hops with the help of AoA measurements. By forwarding distance at each node hop-by-hop, the distance estimations can be flooded to the whole network. Once a sensor node got distance estimations from at least three (in 2-D) or four (3-D) anchor nodes, the location of the sensor node is calculated. Comparing to the existing localization schemes in Ad-Hoc networks: DV-distance, DV-hop, and Euclidean propagation, the simulation results show that our proposed method improves localization accuracy significantly while keeping high localization coverage.
Social Mobilization and Community Engagement Central to the Ebola Response in West Africa: Lessons for Future Public Health Emergencies

Following the World Health Organization (WHO) declaration of a Public Health Emergency of International Concern regarding the Ebola outbreak in West Africa in July 2014 UNICEF was asked to co-lead in coordination with WHO and the ministries of health of affected countries the communication and social mobilization component-which UNICEF refers to as communication for development (C4D)-of the Ebola response. For the first time in an emergency setting C4D was formally incorporated into each countrys national response alongside more typical components such as supplies and logistics surveillance and clinical care. This article describes the lessons learned about social mobilization and community engagement in the emergency response to the Ebola outbreak with a particular focus on UNICEFs C4D work in Guinea Liberia and Sierra Leone. The lessons emerged through an assessment conducted by UNICEF using 4 methods: a literature review of key documents meeting reports and other articles; structured discussions conducted in June 2015 and October 2015 with UNICEF and civil society experts; an electronic survey launched in October and November 2015 with staff from government the UN or any partner organization who worked on Ebola (N = 53); and key informant interviews (N = 5). After triangulating the findings from all data sources we distilled lessons under 7 major domains: (1) strategy and decentralization: develop a comprehensive C4D strategy with communities at the center and decentralized programming to facilitate flexibility and adaptation to the local context; (2) coordination: establish C4D leadership with the necessary authority to coordinate between partners and enforce use of standard operating procedures as a central coordination and quality assurance tool; (3) entering and engaging communities: invest in key communication channels (such as radio) and trusted local community members; (4) messaging: adapt messages and strategies continually as patterns of the epidemic change over time; (5) partnerships: invest in strategic partnerships with community religious leaders journalists radio stations and partner organizations; (6) capacity building: support a network of local and international professionals with capacity for C4D who can be deployed rapidly; (7) data and performance monitoring: establish clear C4D process and impact indicators and strive for real-time data analysis and rapid feedback to communities and authorities to inform decision making. Ultimately communication community engagement and social mobilization need to be formally placed within the global humanitarian response architecture with proper funding to effectively support future public health emergencies which are as much a social as a health phenomenon.
Phase II study of combination of hyperCVAD with ponatinib in frontline therapy of patients (pts) with Philadelphia chromosome (Ph) positive acute lymphoblastic leukemia (ALL).

7024 Background: Combination of chemotherapy with TKIs was evaluated and appears to be effective in Ph+-ALL. Ponatinib is a more potent inhibitor and suppresses the T315I clones, a common cause of ...
Documenting an Endangered Language: The Inclusive First-Person Plural Pronoun Kākou as a Resource for Claiming Ownership in Hawaiian

This study employs tape-recorded data from interviews with elder speakers of Hawaiian conducted in the year 1970 to describe how a specific feature of the Hawaiian language, the first-person inclusive plural pronoun kākou, may be used in discourse as a resource for making claims of ownership on behalf of Hawaiians. To do so, the analysis first invokes Hanks's (2005) notions of deixis and deictic field to show how kākou can create a sense of community among speakers of Hawaiian. Insights from membership category analysis (Sacks 1992; Sacks and Schegloff 1979; Schegloff 2007) are then drawn on to demonstrate how kākou can be interpreted in interaction as a reference to the category of “Native Hawaiian” and how that category can be used to construe specific natural resources, activities, and forms of language as part of a Hawaiian identity. Discussion of the analysis centers on the status of Hawaiian as an endangered language in the midst of a revitalization movement where language and culture have been points of contestation. Usage of kākou to claim ownership is seen as a resource that can allow speakers of Hawaiian to work through the language itself to negotiate what it means to be “Native Hawaiian.”
Occupational Outcomes of Reconstructive Surgery for Adult Acquired Flatfoot Deformity.

ABSTRACT Introduction: Reconstruction of a symptomatic adult flatfoot is an involved operation with a long recovery period. No previous studies have looked at the occupational or functional results of athletically active patients who have undergone this surgery. In the U.S. Military, the rates of return to unrestricted active duty are unknown. Materials and Methods: A retrospective review of all active duty military patients who underwent a reconstructive surgery for adult acquired flatfoot surgery at a single institution from January 2001 to 2015 was performed. Results: 50 patients met inclusion criteria. 28 of 50 patients (56%) remained on active duty with permanent duty restrictions, and only 2 of 50 patients (4%) returned to full duty without restrictions. 20 of 50 (40%) patients underwent a Medical Evaluation Board to separate from the military. A difference was noted in terms of the hindfoot realignment procedure performed: the probability of a Medical Evaluation Board is higher for those patients w...
A fractal-based clustering approach in large visual database systems

Large visual database systems require effective and efficient ways of indexing and accessing visual data on the basis of content. In this process, significant features must first be extracted from image data in their pixel format. These features must then be classified and indexed to assist efficient access to image content. With the large volume of visual data stored in a visual database, image classification is a critical step to achieve efficient indexing and retrieval. In this paper, we investigate an effective approach to the clustering of image data based on the technique of fractal image coding, a method first introduced in conjunction with fractal image compression technique. A joint fractal coding technique, applicable to pairs of images, is used to determine the degree of their similarity. Images in a visual database can be categorized in clusters on the basis of their similarity to a set of iconic images. Classification metrics are proposed for the measurement of the extent of similarity among images. By experimenting on a large set of texture and natural images, we demonstrate the applicability of these metrics and the proposed clustering technique to various visual database applications.
Behavioral modeling of VCSELs for high-speed optical interconnects

Transition from on-off keying to 4-level pulse amplitude modulation (PAM) in VCSEL based optical interconnects allows for an increase of data rates, at the cost of 4.8 dB sensitivity penalty. The resulting strained link budget creates a need for accurate VCSEL models for driver integrated circuit (IC) design and system level simulations. Rate equation based equivalent circuit models are convenient for the IC design, but system level analysis requires computationally efficient closed form behavioral models based Volterra series and neural networks. In this paper we present and compare these models.
Criminal organizations and the policymaking process

What role do criminal organisations play in policymaking? Evidence presented in this paper from Latin America and the Caribbean points to the complex ways that various types of criminal groups infl...
Creating the Intellectual: Chinese Communism and the Rise of a Classification

Creating the Intellectual redefines how we understand relations between intellectuals and the Chinese socialist revolution of the last century. Under the Chinese Communist Party, “the intellectual” was first and foremost a widening classification of individuals based on Marxist thought. The party turned revolutionaries and otherwise ordinary people into subjects identified as usable but untrustworthy intellectuals, an identification that profoundly affected patterns of domination, interaction, and rupture within the revolutionary enterprise. Drawing on a wide range of data, Eddy U takes the reader on a journey that examines political discourses, revolutionary strategies, rural activities, urban registrations, workplace arrangements, organized protests, and theater productions. He lays out in colorful detail the formation of new identities in Chinese society as well as new forms of organization and association. The outcome is a compelling picture of the mutual constitution of the intellectual and the Chinese socialist revolution, the legacy of which still affects ways of seeing, thinking, acting, and feeling in what is now a globalized China. “This is an illuminating study of how the introduction in early twentieth-century China of the new category of ‘intellectual’ not only altered the status of millions of educated Chinese but also transformed the trajectory of Chinese Communism itself.” ELIZABETH J. PERRY, Professor of Government, Harvard University “Innovatively framing the story as a decades-long process, Eddy U conclusively demonstrates the political construction of the ‘intellectual’ as a social category by the Chinese Communist Party. This book deepens our understanding of the tortured relationship between the Chinese Communist Party and these individuals, one that would have catastrophic consequences during the Cultural Revolution.” ANDREW WALDER, Professor of Sociology, Stanford University EDDY U is Associate Professor of Sociology at the University of California, Davis. He is the author of Disorganizing China: Counter-Bureaucracy and the Decline of Socialism.
Biologic modelling of periodontal disease progression

Aim To investigate the synergistic role of biologic markers from saliva, serum and plaque in modelling periodontitis disease progression. Material and methods This longitudinal study evaluated characteristics of disease progression in 114 patients with generalized moderate to severe periodontitis. The primary outcome was detection of sites with progressing attachment loss sites over 6 months in patients who received scaling and root planing or oral hygiene only. The predictive potential of 27 biomarkers in serum, whole saliva and subgingival plaque was evaluated using three classification algorithms (Support Vector Machines; Naive Bayes Classifier; and Linear Discriminant Analysis) within an ensemble predictive modelling framework. Results Disease progression occurred in 24.6% of subjects (28/114). Predictive modelling using Naive Bayes Classifier identified progressors best with sensitivity of ~89%. The use of the three classification algorithms revealed the concerted role of salivary matrix metalloproteinase-8, serum biomarkers (serum amyloid P, matrix metalloproteinase 1, bactericidal permeability-increasing protein, isoprostane) along with levels of Porphryomonas gingivalis and Tannerella forsythia in plaque in predicting progressors. Conclusions Synergistic utility of baseline bacterial and inflammatory biomarkers from saliva, serum and plaque predicted disease progression.
Exploring the differential impact of environmental sustainability, operational efficiency, and corporate reputation on market valuation in high-tech-oriented firms

Abstract In this paper, we explore the strategic significance of three factors – operational efficiency, measured by data envelope analysis; environmental sustainability, represented by Newsweek's Green Rankings; and corporate reputation, based on Fortune's list of most admired companies in the world –and their relationship to the market valuation of high-tech-oriented companies. In particular, we estimate the impact of these factors on Tobin's Q, which represents the overall technological and market strength of a firm as a forward-looking market performance reflecting stakeholders' expectations of the value of a firm. Using complementary regression and a neural network approach, we find that operational efficiency has the largest impact on Tobin's Q, followed by corporate reputation and environmental sustainability. In addition to its findings on the relative importance of these strategic factors, the paper's findings also suggest that operational efficiency, which reflects efficiency-driven best practice and managerial proficiency, is a crucial determinant of the market-facing measure of Tobin's Q in high-tech industries. Using models to estimate the interaction between these variables, we find that environmental sustainability and its interaction with reputation has the largest synergistic effect on Tobin's Q, followed by the interaction of reputation and operational efficiency. Our results show that the interaction of unique performance metrics can provide insights that differ from those derived from models for which the interaction is not included. Furthermore, the discovery of varying impact patterns under distinguishable capabilities is another significant finding of the paper.
Implementing Deep Learning for comprehensive aircraft icing and actuator/sensor fault detection/identification

Abstract The detection and identification for aircraft icing and actuator/sensor fault has been a lasting topic in flight safety researches. The current algorithms are usually tailored for some specific cases (faults/icing locations, magnitude, etc.). Although the performance of the algorithm in the designated cases may be good, the transferring of it to other different cases is usually heavy as parameters tuning or even algorithm redesigning may be required. In this paper, the author advocates exploring a comprehensive scheme that balance both good performance and wide transferability for different cases. Referring to the current advances in other research communities, we follow the state-of-art Deep Learning (DL) and transfer learning (TL) concepts. A scheme for the icing/actuator fault detection using the DL technique is firstly constructed. The TL is then adopted to transfer this scheme to other different tasks, e.g. fault/icing identification, sensor fault detection. Test results show that the TL-enhanced DL scheme exhibits not only good performance for the designated detection task, but also reflects flexible transferability at low tuning efforts. Via this paper the author advocates furtherly exploring the potentials of the novel DL and TL technique as to advancing the researches/techniques in the flight dynamics and control realm.
SYNTHESIS, STEREOCHEMISTRY, AND OPIOID RECEPTOR BINDING ACTIVITY OF HETEROCYCLIC ANALOGUES OF BW373U86

The synthesis of a series of heterocyclic analogues of (±)-4-((αR*)-α-((2S*,5R*)-4-allyl-2,5-dimethyl-1-piperazmyl)-3-hydroxybenzyl)-N,N-diethylbenzarrude (BW373U86) for screening against opioid receptors is described. The intermediate α-heterocyclic benzyl alcohols 24 were synthesized either by low temperature reaction of lithioheterocycles with 3-((tert-butyldimethylsilyl)oxy)benzaldehyde (10) or by reaction of 3-((tert-butyldimethylsilyl)oxy)phenylmagnesium bromide (19) with heterocyclic carbaldehydes. The α-heterocyclic benzyl alcohols 24 were converted to chloromethines (25) with thionyl chloride and used to alkylate with trans-1-allyl-2,5-dimethylpiperazine (5) to give diastereomeric pairs of the target compounds. The bromoheterocycles were then derivatized to produce amides. Compounds that are potent and selective for the 5 or μ opioid receptors and some mixed δ/μ analogues are reported.
Pleistocene preserve: a population growth problem of mammoth proportions

A number of processes that involve large numbers are critical to civic scientific literacy, including many biological topics. Understanding the basic causes of such large-scale processes, such as population growth, speciation, and extinction, are key to engaging evolution and ecology learning. Here we present a teaching module which uses manipulatives to addresses one such topic, population growth, utilizing charismatic organisms, mammoths. The module involves an engaging hypothetical scenario, the restoration of mammoths from extinction (de-extinction) in a captive population being grown to be placed in zoos globally. The module explores both population growth modeling and carrying capacity in relation to both modern elephant conservation and human population growth. We include detailed laboratory instructions for both students and instructors. While we designed and implemented it in a non-majors biology course, further extensions are detailed to utilize more robust modeling and complex scenarios for inquiry-driven majors biology and advanced population ecology courses. This module allows for exploration of a number of concepts within population growth, with natural lead-ins to additional topics. We make the case for mammoths and elephants more generally as charismatic organisms for which students’ familiarity can leverage engagement with many important biological concepts, in this case population growth.