Epidemiological Characteristics of Acquired Immune Deficiency Syndrome in Zhoukou,He'nan Province From 1995 to 2014

Objective To investigate the epidemiological characteristics of acquired immune deficiency syndrome( AIDS) in Zhoukou and to provide scientific evidence for the formulation of prevention and control strategies. Methods We collected the data of HIV- infected patients and AIDS patients in Zhoukou from the Information System for AIDS Prevention and Control of China's Information System for Disease Prevention and Control,with a time range of 1995 to 2014. Results From1995 to 2014,the total reported number of HIV- infected people and AIDS patients in Zhoukou was 9 187,among which 8 215( 89. 42%) were AIDS patents and 3 254( 35. 42%) died. After the exclusion of deceased patients,there were 5 933 HIV-infected patients and AIDS patients surviving,accounted for 67. 37 /105 in all permanent residents of Zhoukou and of which 5 164 were AIDS patients. From 1995 to 2003,with the HIV / AIDS monitoring strengthened,the detected HIV- infected and AIDS patients had been increasing year by year; 2004 witnessed more reported cases than other years,for HIV census was carried out on FPDs this year; from 2005 to 2012,the number of reported cases was in a decreasing trend; from 2013 to 2014,the disease showed a slight rebound. From 2006,death cases began to decrease year by year. HIV- infected patients and AIDS patients of Zhoukou distributed in 204 villages or towns in 10 districts or counties,and significant differences( χ2= 1 181. 0,P 0. 01)existed among the 10 counties or districts in the proportion of surviving cases in permanent residents. There were five first- class AIDS counties and five second- class AIDS counties. Among HIV- infected patients and AIDS patients,the number of male patients was more than female patients,with a ratio of 1. 23∶ 1; the patients were aged from 2 to 82,with a majority ranging from30 to 60,accounting for 83. 37%( 7 659 /9 187). Ratio of survival cases in permanent residents varied significantly among the groups of different genders,ages,urban and rural areas,nationalities,education levels,occupations and marital status. The number of cases found through screening and consultation was the largest,which was 3 365( 36. 63%),and the number of cases found through paid blood / plasma donation and special survey was the second largest,which were 2 928( 31. 87%) and 1 410( 15. 35%). From 2006,the proportion of cases of blood transmission and of mother- to- child transmission in all reported cases was in a downtrend( χ2trend= 1 096. 0,11. 8; P 0. 01),and the proportion of cases by sexual transmission was in an uptrend( χ2trend= 193. 4,P 0. 01). From 2006,the proportion of case by unmarried two- gender sexual transmission was in an increasing trend( χ2trend= 1 419. 0,P 0. 01),and the proportion of case by sexual transmission between spouse or fixed sex partners was in a declining trend( χ2trend= 43. 6,P 0. 01). A case of MSM transmission was first reported in 2007,and the proportion increased after that( χ2trend= 132. 1, P 0. 01). Conclusion In recent years, the epidemic situation of ADIS in Zhoukou has been in a rising trend,with a widespread and aggregated distribution. Relevant clinical detection is a major source of discovering HIV / AIDS. Sexual transmission is replacing blood transmission as the primary route gradually. Unmarried two-gender sexual transmission and MSM transmission are increasing. The prevention of sex transmission is the crucial task for the control of AIDS.