cssi/SciSciGPT-SciSciNet huggingface dataset:
A new association of second-trimester echogenic bowel and metabolic disease of the neonate.

Fetal echogenic bowel is diagnosed in 0.2% to 1.4% of second-trimester ultrasound examinations. 1 It is a nonspecific finding that refers to an increase in echogenicity, or brightness of the fetal bowel, similar to or greater than that of adjacent bone, when the ultrasound gain is turned down to the lowest setting possible. Its presence in the second trimester has been described in association with healthy fetuses, as well as aneuploidy, cystic fibrosis, intrauterine growth restriction, intra-amniotic bleeding, congenital infections, thalassemia, and poor pregnancy outcome. 2,3 Abnormal elevation of maternal serum markers in the second trimester, including α-fetoprotein (AFP) and human chorionic gonadotropin (hCG), along with echogenic bowel have also been associated with adverse perinatal outcomes, including intrauterine fetal death, fetal growth restriction, abruptio placentae, preterm birth, premature rupture of membranes, and pregnancy-induced hypertension. 4-10 However, elevated second-trimester hCG levels with echogenic bowel has not been clearly identified as a risk factor for neonatal mortality, nor has there been any previous association with metabolic disease of the neonate. We describe 2 cases of echogenic bowel associated with elevated maternal serum hCG levels resulting in neonatal mitochondrial trifunctional protein deficiency or long-chain 3-hydroxylacyl-coenzyme A dehydrogenase (LCHAD) deficiency and neonatal deaths.
Impact of obesity on the psychometric properties of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for major depressive disorder

Obesity is associated with several symptoms that are components of the diagnostic criteria for major depressive disorder (MDD). Compared with nonobese individuals, obese individuals report more fatigue, sleep disturbance, and overeating. Obesity might, therefore, impact the psychometric properties of the MDD criteria. The goal of the present report from the Rhode Island Hospital Methods to Improve Diagnostic Assessment and Services project was to examine the impact of obesity on the psychometric characteristics of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition symptom criteria for major depression. Two thousand four hundred forty-eight psychiatric outpatients were administered a semistructured diagnostic interview. We inquired about all symptoms of depression for all patients. The mean sensitivity of the 9 criteria in the nonobese and obese patients was nearly identical (74.6% vs 74.3%). The mean specificity was slightly higher in the nonobese patients (82.0% vs 79.5%). No symptom was more specific in the obese than the nonobese patients, whereas the specificity of increased appetite, increased weight, and fatigue was more than 5% lower in the obese patients. Increased appetite, increased weight, hypersomnia, and fatigue had a higher sensitivity in the obese than the nonobese patients, whereas decreased appetite, weight loss, and diminished concentration had a higher sensitivity in the nonobese than the obese patients. Thus, although there were small differences between obese and nonobese patients in the operating characteristics of some symptoms, the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for MDD generally performed equally well for obese and nonobese patients.
Teaching Women a Lesson Sexually Aggressive and Sexually Nonaggressive Men's Perceptions of Acquaintance and Date Rape

Date and acquaintance rape is a pervasive problem on college campuses. This study assessed the influence of both situational factors and individual differences on college men's perceptions of acquaintance and date rape scenarios. Onset of refusal and duration of relationship factors were found to have influenced men's perceptions of victim and perpetrator accountability as well as their likelihood to label a situation rape. In addition, differences were found in perceptions of men who self-reported engaging in sexually aggressive behaviors and men who did not self-report engaging in sexually aggressive behaviors. Interpretation of findings considered both token resistance and male entitlement explanations.
Fundamentos de Conservación Biológica: Perspectivas Latinoamericanas

R. B. Primack, R. Rozzi, P. Feinsinger, R. Dirzo, F. Massardo (eds.). 2001. Fundamentos de Conservacion Biologica: Perspectivas Latinoamericanas. Fondo de Cul-tura Economica, Mexico, D.F., Mexico, 797 pp. ISBN 968-16-6428-0, price (hardbound), $59.99. Conservation biology, the incorporation of biological principles in the design of strategies for the sustainable management of populations, species, and entire ecosystems, is emerging as a major transdiscipline. Few and far between (although the trend appears to have reversed lately, [e.g., Hunter 2002, Pullin 2002, Van Dyke 2003]), textbooks on conservation biology are difficult to keep updated due to the intrinsic nature of the subject. Also, and almost by necessity, they can only offer a very broad perspective on the conservation issues facing many biomes of the world; consequently, their usage in curricular activities is hindered at colleges and universities in the very places where the most pressing conservation issues occur. This shortcoming is partially abridged by the translation and adaptation of such textbooks into several different languages in different parts of the world. Essentials of Conservation Biology (Primack 1998) is one of the better known textbooks in the discipline and has been translated into several languages (e.g., German, Chinese). The subject of this review is its adapted version in Spanish. It is only fair to emphasize that Fundamentos is not merely a translation of Primack's 1998 book; rather, it is a major undertaking, due not only to the sheer amount of work that coordinating over 117 authors of “study cases” implies, but also to the amount of material covered and the substantial rewriting of the original text in order to redirect its focus to one that …
Power-aware issue queue design for speculative instructions

Speculatively issued instructions may be particularly sensitive to increases in pipeline depth. Our results indicate that as pipeline depth increases, speculation increases the percentage of issue queue instructions that are waiting to be potentially re-issued in case of a mis-speculation. To compensate, issue queues are larger and thus more power hungry. We propose an alternative design called the Dual Issue Queue, that retains pre- and post-issue instructions in separate, smaller queues, saving 18% of issue queue power dissipation without degrading performance.
Nematomorpha (Horsehair Worms)

The phylum Nematomorpha, the hairworms, occurs worldwide. All members are developmental parasites of aquatic or terrestrial invertebrates. One genus, Nectonema, is marine, whereas the remaining species occur in freshwater as free-living stages or inside terrestrial hosts. Hairworms have two or more hosts in their life cycle. The first paratenic host is just a carrier to the second developmental host. In the developmental host, the hairworm grows to maturity and often kills the host upon emergence. There is no direct economic or medical importance of hairworms and while they can reach up to a foot in length, they are rarely seen. A few species may effect populations of herbivorous insects, but most are not important as biological control agents. Most freshwater hairworms are threatened from polluted waters, habitat displacement and reduced host populations. Many could be considered as candidates for the Red Data Book of rare and endangered species. Hairworms are a relict group that is not closely related to any other living phylum. The preparasitic larvae are quite different from the adults since they possess spines for entering the body cavity of paratenic hosts. Once inside the paratenic host, the larva is surrounded by host tissue and is known as an ‘encysted’ larva. It remains in the cyst until the paratenic host is ingested by a suitable developmental host. If the second host is not suitable for development, the hairworm larvae can encyst again in the new paratenic host. Key Concepts: Hairworms are becoming endangered in many areas of the world. Hairworms have attracted the attention of behaviourists who study how these parasites control the movements of their hosts. Hairworms have no direct economic or medical importance. Hairworms have the ability to arrest development in nondevelopmental hosts. Hairworms are an enigmatic group that are not closely related to any other invertebrates. Hairworms are an ancient group, with fossils dating back to the Early Cretaceous. Keywords: nematomorpha; gordiaceae; hairworm; horsehair worm; marine hairworm; Nectonema; freshwater hairworm
Fast temperature-programmed gas chromatography-mass spectrometry for food analysis.

Fast temperature-programmed gas chromatography (FTGC) is evaluated. A modified capillary column allowing temperatureprogram rates as high as 20°C/s is operated with mass spectrometric detection (MSD). FTGC methods are developed for the analysis of off-flavors in water, derivatized sugars, and fatty acid methyl esters. Liquid injection and solid-phase microextraction are evaluated. Although the resolution can be somewhat lower than analysis with a traditional column, time savings are significant. Analysis times range from 2 to 4.5 min compared with 20 to 60 min for conventional methods. MSD allows for the analysis of some coeluting peaks, which allows for quantitation even when peaks coelute.
Thoughts on the Two Translations of Heidegger’s Beiträge

The following reflections examine the new translation of Heidegger’s Beitrage zur Philosophie (Vom Ereignis) in relation to the former one. These reflections assess the relative merits of both translations and attempt to show how this relation illustrates specific issues in Heidegger’s text concerning the first and other beginnings of Western thought.
Administrators' Understanding and Use of Family-Centered Practices

Employing qualitative methods, administrators’ understanding and use of family-centered practices were examined. Results indicate differences in role perceptions and service delivery based on their...
Integrating addiction treatment into primary care using mobile health technology: protocol for an implementation research study

Healthcare reform in the United States is encouraging Federally Qualified Health Centers and other primary-care practices to integrate treatment for addiction and other behavioral health conditions into their practices. The potential of mobile health technologies to manage addiction and comorbidities such as HIV in these settings is substantial but largely untested. This paper describes a protocol to evaluate the implementation of an E-Health integrated communication technology delivered via mobile phones, called Seva, into primary-care settings. Seva is an evidence-based system of addiction treatment and recovery support for patients and real-time caseload monitoring for clinicians. Our implementation strategy uses three models of organizational change: the Program Planning Model to promote acceptance and sustainability, the NIATx quality improvement model to create a welcoming environment for change, and Rogers’s diffusion of innovations research, which facilitates adaptations of innovations to maximize their adoption potential. We will implement Seva and conduct an intensive, mixed-methods assessment at three diverse Federally Qualified Healthcare Centers in the United States. Our non-concurrent multiple-baseline design includes three periods — pretest (ending in four months of implementation preparation), active Seva implementation, and maintenance — with implementation staggered at six-month intervals across sites. The first site will serve as a pilot clinic. We will track the timing of intervention elements and assess study outcomes within each dimension of the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework, including effects on clinicians, patients, and practices. Our mixed-methods approach will include quantitative (e.g., interrupted time-series analysis of treatment attendance, with clinics as the unit of analysis) and qualitative (e.g., staff interviews regarding adaptations to implementation protocol) methods, and assessment of implementation costs. If implementation is successful, the field will have a proven technology that helps Federally Qualified Health Centers and affiliated organizations provide addiction treatment and recovery support, as well as a proven strategy for implementing the technology. Seva also has the potential to improve core elements of addiction treatment, such as referral and treatment processes. A mobile technology for addiction treatment and accompanying implementation model could provide a cost-effective means to improve the lives of patients with drug and alcohol problems. ClinicalTrials.gov ( NCT01963234 ).
Are Gender Stereotypes Bad for Women? Rethinking Antidiscrimination Law and Work-Family Conflict

The work-family conflict is a significant barrier to women's equality in the workplace. As many commentators have noted with envy, the United States stands apart from most European countries in its failure to give women a legal right to paid maternity leaves. This Article argues that the United States' potential for reconciling the work-family conflict is undermined by the predominance of antidiscrimination law in tackling the problem. To expose this American idiosyncrasy, this Article develops a thorough comparative analysis of successful European models for work-family reconciliation. The unique trajectory of U.S. antidiscrimination law has pushed family and medical leave into a single legal regime, leading to maternity leaves that are grossly inadequate and medical leaves that are easily abused. In France and Sweden, by contrast, maternity is given special, generous protections, while sickness leaves are less generous and administered separately. European countries' laws are paternalistic towards women, protecting the special relationship between a woman and her child. The American amalgamation of family and medical leave is the result of an antidiscrimination framework that combats paternalism and gender stereotypes, such as the assumption that women, rather than men, tend to be primary caregivers. But today, due to the costs and fears of abuse of sick leaves, treating maternity the same as illness forecloses the possibility of generous maternity leaves. This Article critiques both the American antidiscrimination approach as well as the gender-conscious European family-policy approach to synthesize new ways of reorienting the American legal frameworks for family and medical leave.
Probabilistic Polling And Voting In The 2008 Presidential Election Evidence From The American Life Panel

This article reports new empirical evidence on probabilistic polling, which asks persons to state in percent-chance terms the likelihood that they will vote and for whom. Before the 2008 presidential election, seven waves of probabilistic questions were administered biweekly to participants in the American Life Panel (ALP). Actual voting behavior was reported after the election. We find that responses to the verbal and probabilistic questions are well-aligned ordinally. Moreover, the probabilistic responses predict voting behavior beyond what is possible using verbal responses alone. The probabilistic responses have more predictive power in early August, and the verbal responses have more power in late October. However, throughout the sample period, one can predict voting behavior better using both types of responses than either one alone. Studying the longitudinal pattern of responses, we segment respondents into those who are consistently pro-Obama, consistently anti-Obama, and undecided/vacillators. Membership in the consistently pro- or anti-Obama group is an almost perfect predictor of actual voting behavior, while the undecided/vacillators group has more nuanced voting behavior. We find that treating the ALP as a panel improves predictive power: current and previous polling responses together provide more predictive power than do current responses alone.
Viable: yes, no, or somewhere in the middle?

Viability testing plays a key role in the treatment of patients with ischemic cardiomyopathy. We have long known that, for patients with coronary artery disease, having decreased left ventricular function carries an increased risk of mortality, hospital stay, arrhythmia, and decreased quality of
Cardiac Rehabilitation in Left Ventricular Assist Device Recipients: Can it Bolster the Benefits of Restored Flow?∗

In appropriately selected advanced heart failure (HF) patients, treatment with a left ventricular assist device (LVAD) is associated with significant improvements in physical function and quality of life (QOL) [(1)][1]. However, despite these improvements, impairments persist, with functional
Optical Signatures of Dissolved Organic Matter Transformation in the Global Ocean

Characterization of dissolved organic matter in terms of its composition and optical properties, with an eye toward ultimately understanding its deep ocean dynamics, is the currently active frontier in DOM research. We used UV-visible absorption spectroscopy and fluorescence excitation-emission matrix (EEM) spectroscopy to characterize dissolved organic matter in the open ocean along sections of the U.S. CO2/CLIVAR Repeat Hydrography Project located in all the major ocean basins outside the Arctic. Despite large differences in fluorescence intensity between ocean basins, some variability patterns were similar throughout the global ocean, suggesting similar processes controlling the composition of the DOM. We find that commercially available single channel CDOM sensors are sensitive to the fluorescence of humic materials in the deep ocean and thermocline but not to the UVA-fluorescing and absorbing materials that characterize freshly produced CDOM in surface waters, revealing fundamental diversity in the DOM profile. In surface waters, UVA fluorescence and absorption signatures indicate the presence of freshly produced material and the process of bleaching removal, but in the upper mesopelagic and in the main thermocline these optical signatures are replaced by those of humic materials, with distribution patterns correlated to apparent oxygen utilization and other signatures of remineralization. Empirical orthogonal analysis (EOF) of the EEM data suggests the presence of two (unidentified) processes which convert “fresh” DOM to humic materials: one located in the surface ocean (shallower than 500m) and one located in the main thermocline. These hypothetical humification processes represent less than 5% of the overall variability in oceanic humic DOM fluorescence, which appears to be dominated by terrestrial input and solar bleaching of humic materials.
This Too Shall Pass: Evidence of Coping and Fading Emotion in African Americans' Memories of Violent and Nonviolent Death

Two studies examined African Americans essays on coping with violent and nonviolent death and fading affect bias. Essays from 101 African Americans were coded for psychological resolution (resolved or unresolved) and for type of death (violent or nonviolent). Linguistic analyses were used to examine the experience of loss and coping methods. Religious coping was important for nonviolent death events while social support and emotion (e.g., crying) were themes that emerged for violent death events. For unresolved violent death events, dissociation was a common theme. The perceived change in the emotional intensity of the events was examined and revealed that the negative emotion showed evidence of substantial fading. Overall, these results suggest religious coping, social support and sharing enhance coping among African American participants. These processes can help negative affect associated with death events fade, allowing for psychological resolution, healing, and resilience.
Equivalent Volume and Comovement

I measure the amount of a stock that trades indirectly through its inclusion in Exchange-Traded Funds (ETFs), which I call equivalent volume. I hypothesize that the equivalent volume of an ETF component stock is related to its comovement with the other ETF component stocks due to the trading pressure caused by arbitrage. Using a proprietary ETF holdings data and dynamic conditional correlations, I find strong evidence of a positive relation between comovement and contemporaneous equivalent volume. My findings contribute to the literature on trading volume and comovement by relating arbitrage-induced trading pressure to the underlying stock comovement.
Function of NF-kappa B/Rel binding sites in the major histocompatibility complex class II invariant chain promoter is dependent on cell-specific binding of different NF-kappa B/Rel subunits.

Abstract The promoter of the human major histocompatibility complex class II-associated invariant-chain gene (Ii) contains two NF-kappa B/Rel binding sites located at -109 to -118 (Ii kappa B-1) and -163 to -172 (Ii kappa B-2) from the transcription start site. We report here that the differential function of each of these NF-kappa B/Rel sites in several distinct cell types depends on cell-specific binding of NF-kappa B/Rel transcription factors. Ii kappa B-1 is a positive regulatory element in B-cell lines and in the Ii-expressing T-cell line, H9, but acts as a negative regulatory element in myelomonocytic and glia cell lines. In vivo protein-DNA contacts are detectable at Ii kappa B-1 in cell lines in which this site is functional as either a positive or negative regulator. Electrophoretic mobility supershift assays determine that members of the NF-kappa B/Rel family of transcription factors can bind to this site in vitro and that DNA-binding complexes that contain p50, p52, p65, and cRel correlate with positive regulation whereas the presence of p50 correlates with negative regulation. Ii kappa B-2 is a site of positive regulation in B-cell lines and a site of negative regulation in H9 T cells, myelomonocytic, and glial cell lines. In vivo occupancy of this site is observed only in the H9 T-cell line. Again, in vitro supershift studies indicate that the presence of p50, p52, p65, and cRel correlates with positive function whereas the presence of only p50 and p52 correlates with negative function. This differential binding of specific NF-kappa B/Rel subunits is likely to mediate the disparate functions of these two NF-kappa B/Rel binding sites.
TEMPORAL RELATIONSHIP BETWEEN EPISODES OF ATRIAL FIBRILLATION AND INCIDENT STROKE IN PATIENTS WITH AN IMPLANTABLE CARDIAC DEVICE

There is limited and conflicting data on the temporal relationship between atrial fibrillation (AF) episodes and occurrence of stroke/TIA. We sought to evaluate this relationship in patients with implantable cardiac devices (CIED) presenting with stroke. We performed a retrospective, single center
Workload acceleration with the IBM POWER vector-scalar architecture

In this paper, we describe the history and development of the IBM POWER ® vector-scalar architecture, as well as how the design goals of hardware efficiency and software interoperability are achieved by integrating existing floating-point and vector functions into a new unified architecture and function unit. The vector-scalar instructions were defined with an emphasis on out-of-the-box performance and consumability, while accelerating a broad set of enterprise server workloads. Vector-scalar instructions were first introduced in the IBM POWER7 ® architecture to accelerate high-performance computing applications. With the introduction of the POWER8 ® processor, the vector-scalar architecture expanded to accelerate a diverse set of enterprise workloads including unstructured text and string processing, business analytics, in-memory databases, big data, and stream coding. We conclude this paper with a description of workload performance and application acceleration to demonstrate the effectiveness of the new vector-scalar architecture.
Racial and sexual minority women's receipt of medical assistance to become pregnant.

Objective: This study aimed to determine rates at which racial minority (i.e., non-White) and sexual minority (i.e., lesbian and bisexual-identified) women in the United States receive medical help to become pregnant. Income and insurance coverage discrepancies were hypothesized to mediate differences in receipt of medical help as a function of race and sexual orientation. Method: Two studies compared rates at which adult women ages 21–44 reported receiving medical help to become pregnant as a function of race and sexual orientation, using data from 2 cycles of the National Survey of Family Growth (the 2002 wave in Study 1, and the 2006–2010 wave in Study 2). Mediation analyses controlling for age and education level evaluated whether race and sexual orientation were positively associated with receipt of medical pregnancy help, as mediated by insurance coverage and income. Results: Heterosexual White women reported receiving medical fertility assistance at nearly double the rates of women who identified as non-White, sexual minority, or both. Differences in rates of help received by White and non-White groups were only partially mediated by insurance coverage and income in both studies. Insurance and income discrepancies accounted for all differences between sexual minority and heterosexual women’s receipt of pregnancy help in Study 1; insurance coverage alone explained differences in Study 2. Conclusions: Researchers often indicate that economic differences are responsible for health disparities between minority and majority groups, but this may not be the case for all women pursuing medical fertility assistance. Possible origins of these disparities are discussed.
Narratology and translation

In their explorations of narrative, many narratologists distinguish between the narrated (the situations and events presented), the narrating (the way these situations and events are presented), an...
Abstract LB-160: CYP4F isoform expression and 20-HETE synthesis in prostate cancer cells are regulated by androgen and contribute to growth

20-hydroxyeicosatetraenoic acid (20-HETE), a CYP450-derived arachidonic acid metabolite in the microcirculation, contributes to vascular tone and stimulates vascular and epithelial cell proliferation, angiogenesis and inflammation, all of which play a role in cancer progression. Our laboratory identified 20-HETE as the mediator of androgen-induced hypertension. Given that androgen contributes to the pathogenesis of prostate cancer, we examined the presence and function of 20-HETE in human prostate cancer cells. Androgen-responsive prostate cancer cells, LNCaP, produced 2-fold more 20-HETE compared to androgen-nonresponsive C4-2 cells (565±139 pg/mg protein vs 223±50 pg/mg protein). Both C4-2 and LNCaP produced greater amount of 20-HETE compared with U87 glioma, MCF-7 breast cancer and ML-1 thyroid cancer cells. 20-HETE levels in prostate primary stromal cells and epithelial RWPE-1 cells were barely detected (16±26 and 23±40 pg/mg protein respectively). Treatment of LNCaP with 5 alpha-dihydrotestosterone (DHT) stimulated 20-HETE production by 65% when compared to vehicle control. DHT treatment did not alter 20-HETE levels in C4-2. Treatment of C4-2 and LNCaP with HET0016, an inhibitor of 20-HETE synthesis, selectively decreased endogenous 20-HETE production while inhibiting cell growth in a dose-dependent manner. Further addition of exogenous 20-HETE stimulated growth. CYP4F2, CYP4F3 and CYP4F8 mRNA levels were several fold higher in LNCaP compared with C4-2, while levels of CYP4A11 and CYP4A22 mRNA were unchanged. In LNCaP, DHT increased CYP4F isoform expression without altering the CYP4A expression; flutamide abrogated DHT-induced expression of CYP4F2 and CYP4F3 but did not affect expression of CYP4F8. Importantly, flutamide inhibited DHT-stimulated 20-HETE production. These results suggest that 20-HETE has an important role in cancer cell proliferation and CYP4F2/3 might be the source of androgen-driven 20-HETE synthesis via androgen receptor dependent pathway. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr LB-160. doi:1538-7445.AM2012-LB-160
FRI0463 Outcomes of Vascular Interventions in Takayasu's Arteritis; A Retrospective Cohort Study

Background Takayasu9s arteritis (TAK) is a large-vessel vasculitis of unknown etiology affecting primarily the aorta and its branches. Despite treatment with immunosuppressive agents patients with TAK often develop arterial damage requiring vascular procedures. (1) Objectives To compare the outcomes between vascular surgery and endovascular procedures in a cohort of patients with TAK. Methods A retrospective medical record review was performed to identify all patients with TAK who underwent vascular procedures at a tertiary referral center between 01/01/1984 and 12/31/2009. The ACR criteria for TAK were used for inclusion (modified to include patients diagnosed between age 41 and 50 years). Disease activity was assessed according to the Kerr criteria. Data are reported using descriptive statistics, and Kaplan Meier methods for complication rate. Results The cohort included 66 patients with TAK (Mean age 33.3±11.0, 58 women [88%], white [70%]) who underwent 119 vascular procedures (surgery 93[78%]; endovascular repair 26 [22%]). The most frequent indications for vascular surgery were arm claudication (40[43%]) and leg claudication (18[19%]) while arm claudication (8[31%]) and malignant hypertension (6[23%]) were the most frequent indications for endovascular repair. In 55 of 93 (59%) vascular surgical procedures and in 10 of 26 (38%) endovascular procedures, the disease was active within 1 month of intervention. The most frequent arterial lesions requiring intervention were the aorta (26[28%]), carotid (21[23%]) and subclavian (20[22%]) arteries in the vascular surgery group compared to the subclavian (9[35%]), renal arteries (5[19%]) and aorta (5[19%]) in the endovascular repair group. Corticosteroids were the most common pharmacological treatment (43[46%] in the surgery group and 12[46%] in the endovascular repair group) followed by immunosuppressants (26[28%] in the surgery group and 10[38%] in the endovascular repair group). The levels of ESR and CRP one month before surgery did not differ between the groups, but these data were available for p =0.19). Other late complications included thrombosis 2[4%], stroke 1[2%] and others 8[11%]) after surgery and development of new pseudoaneurysm 1[10%]) after endovascular repair. Conclusions In this cohort of patients with TAK undergoing vascular intervention, revascularization procedures are associated with high failure rates and frequent operative complications. We observed a trend towards higher rate of restenosis in patients who underwent endovascular procedures, compared to vascular surgery. References Schmidt J, et al. Mayo Clin Proc. 2013 Aug;88(8):822–30. Disclosure of Interest None declared DOI 10.1136/annrheumdis-2014-eular.3760
Application of micro agglutination test in brucellosis surveillance

Objective:To Validate the effect of Micro Agglutination Test(MAT) in brucellosis surveillance and find a simple,quick,economical and good test for a great deal of samples of human and animals.Methods:1189 blood serums collected from the high risk group of brucellosis were tested by MAT and RBPT.The results were analysed.Results:Brucellosis was prevalence in high risk group in Shijiazhuang city.The positive rate of brucellosis in males was 7.91%,and most of them were young adults.There is no significance between MAT and RBPT.Conclusion:MAT can be greatly used for brucellosis surveillance in human and animal samples.
Accommodation succession (δA/δS) sequence stratigraphy: observational method, utility and insights into sequence boundary formation

The future of sequence stratigraphy depends on stratigraphers making observations with a common method so that physical frameworks can be clearly separated from interpretations of driving mechanisms. Depositional sequence boundary selection is a well-known controversy that could be resolved with objective recognition criteria. Accommodation succession sequence stratigraphy refines traditional methods, using sedimentary facies, facies associations, vertical stacking, stratal geometries and stratal terminations as the objective record of competing rates of accommodation change and sediment fill through time. Observations are placed in context of lateral (transgression and regression) and vertical (aggradation and degradation) movement of shoreline through time, across multiple timescales in hierarchal stacks. The repeating motif consists of a subaerial unconformity and its correlative subaqueous surface overlain in coastal settings by a basinward shift in coastal onlap and strata with progradational to aggradation stacking, then retrogradation and aggradation–progradation–degradation stacking. These stacking patterns are bounded by key surfaces, recognized by stratal terminations and characteristic vertical successions of facies. This pattern is independent of time duration or position on a sea-level curve, but incorporates data resolution, regional extent and hierarchal stacking. Examples from multiple datasets show the utility and objectivity of the method and provide insights into sequence boundary formation.
Na+-H+ antiporter of rat colonic basolateral membrane vesicles.

The present experiments were conducted, using acridine orange and 22Na uptake techniques, to demonstrate the presence of an electroneutral Na+-H+ exchange process in rat colonic basolateral membrane vesicles. Results consistent with the existence of a distinct Na+-H+ antiporter in these vesicles include the following: 1) an outwardly directed Na+ gradient stimulated proton influx (Na+in, 100 mM; pHin 7.5/pHout 7.5) and an inwardly directed sodium gradient (Na+out, 5-50 mM; pHin 6.0/pHout 7.5) stimulated proton efflux; 2) sodium-stimulated proton influx was minimally decreased (approximately 10-25%) under voltage clamp conditions (addition of valinomycin in the presence of K+ on both sides of vesicles), indicating that Na+ for H+ exchange in these vesicles could not be explained solely on the basis of a membrane potential; 3) an outwardly directed proton gradient (pHin 5.5/pHout 7.5) stimulated 22Na uptake into these vesicles and a threefold "over-shoot" was observed; 4) 22Na uptake and sodium-stimulated p...
My Body/Myself: Lessons from Dance Education (2004)

The author describes this essay as a “duet” between personal knowledge (her own lived experience as a dance educator) and critical social theory. As a structure, she describes three themes pervading what she has learned and taught, ones which have implications well beyond dance and teaching: Feeling from the inside to understand self and others (internal, somatic sensing); Self-direction/self-management (recognizing power to make conscious choices); and The body as a source for knowledge and meaning.
Vitamin D deficiency is independently associated with greater prevalence of erectile dysfunction: The National Health and Nutrition Examination Survey (NHANES) 2001-2004.

Abstract Background and aims Erectile dysfunction (ED) and atherosclerotic cardiovascular disease (ASCVD) share many common risk factors, and vascular ED is a marker for increased ASCVD risk. Low 25-hydroxyvitamin D [25(OH)D] concentrations have been associated with increased ASCVD risk, but less is known regarding the relationship of low 25(OH)D with ED. We determined whether 25(OH)D deficiency is associated with ED independent of ASCVD risk factors. Methods We performed cross-sectional analyses of 3390 men aged ≥20 years free of ASCVD who participated in NHANES 2001–2004. Serum 25(OH)D was measured by the DiaSorin radioimmunoassay; deficiency was defined as levels Results After accounting for NHANES sampling, the weighted prevalence of 25(OH)D deficiency and of ED were 30% and 15.2%, respectively. 25(OH)D levels were lower in men with vs. those without ED (mean 22.8 vs 24.3 ng/mL, respectively; p = 0.0005). After adjusting for lifestyle variables, comorbidities, and medication use, men with 25(OH)D deficiency had a higher prevalence of ED compared to those with levels ≥30 ng/ml (Prevalence Ratio 1.30, 95% CI 1.08–1.57). Conclusion In this cross-sectional analysis of a representative sample of U.S. men, vitamin D deficiency was associated with an increased prevalence of ED independent of ASCVD risk factors. Additional research is needed to evaluate whether treating vitamin D deficiency improves erectile function.
Dispute Resolution and Spiritual Congruity

A survey of various conflict resolution approaches suggests a correlation between spiritual traditions and conflict resolution strategies. Moreover, Western societies' approaches to dispute resolution appear incongruent with stated spiritual and cultural values.
New electrical insulating mineral oils

Since World War I, electrical insulating oils for transformers and allied electrical equipment have been refined from naphthenic petroleum crude oil stocks. The resulting oils show little or no wax formation and have acceptable dielectric, mechanical and heat transfer properties at temperatures down to −40°C. Usable naphthenic crude oils are coming into short supply and there is a real possibility of a short-fall in supply of the traditional oils in the 1980's. This progress report describes selected portions of work done during the first third of a program directed toward evaluation of potential replacement liquids, particularly other mineral oils.
A data-driven modeling approach for digital material additive manufacturing process planning

Current analytic approaches for additive manufacturing (AM) of digital materials, which are also known as multi-material composites, are either based on physical modeling or computer simulations, which limit the accuracy and efficiency, and do not allow for the new material exploitation. Moreover, decisions on material choices and process settings are made based on trial-and-error experiments. Extensive labor process planning and unpredictable manufacturing results remain to be significant challenges and hinder the advancement of digital material AM technology greatly. Hence, to enable reliable online manufacturing process planning for existing and new digital materials, a data-driven modeling approach is presented in this paper. The manufacturing process planning for digital material AM on a diverse set of materials with various properties is automated by using a data-driven approach. To illustrate the effectiveness of the approach, the drop-on-demand jetting process is studied. Effects of various process parameters on printing results are analyzed.
Equations of Motion of an Aircraft

In this chapter, we apply the results derived in Chap. 1, to deduce the equations of motion of an aircraft. Specifically, we discuss a choice of the aircraft state vector and body reference frame, which are suitable for the study of the stability properties of aircraft. An entire section is dedicated to the analysis of the functional dependencies of the forces and the moment of the forces acting on an airplane so that the equations of motion can be simplified without losing meaningfulness. After having provided the equations of motion of an aircraft in terms of the Tait-Byran angles and the Euler parameters, we linearize these equations. Since the aircraft dynamics is captured by a set of implicit nonlinear differential equations, the details of this linearization process are discussed at length. Lastly, we decouple the linearized equations of motion of an aircraft, we apply the modal decomposition technique to analyze the short period and phugoid modes characterizing the longitudinal dynamics, and we discuss the roll, the spiral, and Dutch roll modes characterizing the lateral-directional dynamics.
Ex vivo retrieval and cryopreservation of oocytes from oophorectomized specimens for fertility preservation in a BRCA1 mutation carrier with ovarian cancer

Objective To report a case of ex vivo oocyte retrieval from oophorectomized specimens in a BRCA1 mutation carrier undergoing surgical staging for ovarian cancer. Design Video case report and literature review. Setting University-affiliated center. Patient(s) A 37-year-old single woman, gravida 0, with a known BRCA1 mutation, presented to her oncologist with a complex right ovarian mass and elevated CA-125 level. Ovarian cancer was suspected, and the patient consented to complete surgical staging. Although she desired to cryopreserve oocytes for fertility preservation, conventional oocyte retrieval was deemed unsafe because follicular puncture would compromise the integrity of the ovarian capsule, thereby increasing the risk of malignant cell spillage and cancer upstaging. Intervention(s) Luteal-phase ovarian stimulation with gonadotropins and letrozole was performed. Surgical staging was initiated 34 hours after the administration of the ovulatory trigger. Main Outcome Measure(s) Ex vivo retrieval of oocytes from bilateral oophorectomized specimens under direct visualization at the time of surgical staging. Result(s) Seven mature oocytes were retrieved and vitrified. Concomitant surgical staging was completed. Conclusion(s) The present case highlights the feasibility of ex vivo or extracorporeal retrieval of mature oocytes from oophorectomized specimens in patients with ovarian cancer. By avoiding follicular puncture within the pelvic cavity, it minimizes the risk of malignant cell spillage and cancer upstaging.
Short frontal plane fractures involving the dorsoproximal articular surface of the proximal phalanx: Description of the injury and a technique for repair.

Background Chip fractures of the dorsoproximal articular margin of the proximal phalanx are common injuries in racehorses. Large fractures can extend distal to the joint capsule insertion and have been described as dorsal frontal fractures. Objectives To report the location and morphology of short frontal plane fractures involving the dorsoproximal articular surface of the proximal phalanx and to describe a technique for repair under arthroscopic and radiographic guidance. Study design Single centre retrospective case study. Methods Case records of horses with frontal plane fractures restricted to the dorsoproximal epiphysis and metaphysis of the proximal phalanx referred to Newmarket Equine Hospital were retrieved, images reviewed and lesion morphology described. A technique for repair and the results obtained are reported. Results Twenty-two fractures in 21 horses commencing at the proximal articular surface exited the dorsal cortex of the proximal phalanx distal to the metacarpophalangeal/metatarsophalangeal joint capsule in 17 hind- and 5 forelimbs. All were in Thoroughbred racehorses. In 16 cases these were acute racing or training injuries. Twenty fractures were medial, one lateral and one was midline. All were repaired with a single lag screw using arthroscopic and radiographically determined landmarks. Sixteen horses raced after surgery with performance data similar to their pre-injury levels Main limitations The study demonstrates substantial morphologic similarities between individual lesions supporting a common pathophysiology but does not identify precise causation. There are no cases managed differently that might permit assessment of the comparative efficacy of the treatment described. Conclusions Short frontal plane fractures involving the dorsoproximal margin of the proximal phalanx that exit the bone distal to the metacarpophalangeal/metatarsophalangeal joint capsule have substantial morphologic similarities, are amenable to minimally invasive repair and carry a good prognosis for return to training and racing. This article is protected by copyright. All rights reserved.
Comparative effectiveness research methodology using secondary data: A starting user's guide.

Abstract Background The use of secondary data, such as claims or administrative data, in comparative effectiveness research has grown tremendously in recent years. Purpose We believe that the current review can help investigators relying on secondary data to (1) gain insight into both the methodologies and statistical methods, (2) better understand the necessity of a rigorous planning before initiating a comparative effectiveness investigation, and (3) optimize the quality of their investigations. Main Findings Specifically, we review concepts of adjusted analyses and confounders, methods of propensity score analyses, and instrumental variable analyses, risk prediction models (logistic and time-to-event), decision-curve analysis, as well as the interpretation of the P value and hypothesis testing. Conclusions Overall, we hope that the current review article can help research investigators relying on secondary data to perform comparative effectiveness research better understand the necessity of a rigorous planning before study start, and gain better insight in the choice of statistical methods so as to optimize the quality of the research study.
Ethics and Accountability and the Challenges

Although the question of ethics in public life has existed from the earliest times of human existence, it has achieved increased prominence because of globalization. The annual data on corruption published by Transparency International and other agencies made it available for the concerned citizens about their country’s status on the corruption index. The countries of the world, especially the developing countries, can no longer keep the lid on corruption. Although many developing countries try to ignore their status on corruption, their governments now know that they are being watched by the people of the world and may be under pressure to take action. Khan analyzes the major theories regarding ethics and investigates the current issues of privacy, organizational politics, justice, fairness, contracting, ethical climate, corruption and violence, and global ethics. The chapter also contains a statistical analysis of corruption and globalization and shows the link between the two phenomena.
Ben Wright: A Multi-facet Analysis

Dr. Benjamin D. Wright believed and taught that to understand the ways of the world, it is necessary to measure all relevant aspects on the same scale. When measurements are on the same scale, it is possible to do accurate comparisons and proper ordering. In this light the multi-facet model was developed. This is a “not so scientific” study of the multi-faceted aspects of Dr. Benjamin D. Wright. Three attributes were identified for the purposes of this study: (1) Contributions to Objective Measurement, (2) Attributes as a Teacher and Professor, and (3) Personal Attributes. Data were collected and analyzed using the multi-facet model, yielding a complex pattern of results for a multi-faceted person. The real story is the development the multi-facet model. We are grateful to Ben Wright and Mike Linacre for making this tool available to measurement professionals.
Toward Feasible Implementation Support: E-Mailed Prompts to Promote Teachers' Treatment Integrity

Although high levels of intervention implementation are more likely to lead to improved student outcomes, educators struggle to maintain high implementation levels over time. School psychologists m...