cssi/SciSciGPT-SciSciNet huggingface dataset:
Broadening the Conceptual and Phenomenological Scope of Offshoring

Offshoring is an important economic and social phenomenon that is not confined to the firm-to-firm relationships emphasized in the management and international business literatures. Global sourcing strategic relationships also exist between firms, governments, and non-governmental organizations, and merit a re-examination of the phenomenological and conceptual scope of offshoring. We identify some contrasting assumptions about the roles and responsibilities of different actors in the global business environment, and offer some “provocations” designed to stimulate the rethinking of offshoring within the emerging global social and economic environment.
Tone and Affixation in Hausa

In terms of their tonal behavior, Hausa affixes can be divided into two types. Tone integrating affixes (TIA's), all of which are suffixes, spread their tone(s) over the stem to which they are attached, overriding lexical stem tone in the process. Tonal assignment takes place in a regular right-to-left manner. Tone non-integrating affixes (TNI's) do not affect stem tone, the tone of resultant words simply being the sum of the parts. Most inflectional and derivational suffixes in Hausa, e.g. noun plurals and verbal grades, are tone integrating. Tone non-integrating affixes include a few suffixes, e.g. :waa "participial" and -aa "feminine", and the prefixes ba- "ethnonymic" and ma- "agential/instrumental/locational". Stems in Hausa typically drop their final vowel when a TIA is added; with most, but not all, TNI's, the stem-final vowel is retained.
Dynamic Alarm Management in Next Generation Process Control Systems

Current process control systems are composed of a large number of components and subsystems operating at different layers of the control system architecture model (i.e. measurement and control devices, Distributed Control Systems, Advanced Process Control systems, and Manufacturing Execution Systems). The IMC-AESOP project aims at designing the next generation architecture of process automation systems. In order to ensure system scalability and modularity, the new architectural design follows the SOA (Service-Oriented Architecture) design principles. Moreover, the design assumes adoption of various technologies with the aim to enable the control systems to meet all functional and performance requirements. The CEP (Complex Event Processing) technology has been selected for being able to provide efficient asynchronous communication (within and across architecture layers) and the capability of temporal reasoning over large amounts of system-generated events. This paper describes the intermediate results of the IMC-AESOP project, outlining the architectural concepts related to the use of the SOA and CEP technologies in the context of advanced alarm management applications - alarm load shedding and state-based alarming.
Fibrinolysis and Vasoactive Peptides in Anaphylaxis

During the complex sequence of events in allergic and anaphylactic states, proteases, anticoagulants, histamine, 5-hydroxytryptamine, catecholamines, hypotensive polypeptides, and many other biologically active principles may appear in different animal species. The mechanism of activation and/or release of these factors is understood poorly, as are their respective roles in the biochemical chain of events in different types of shock.
Improved methods for hemagglutination studies with arthropod-borne viruses.

SummaryModifications are described for the method of carrying out hemagglutination-inhibition tests with arthropod-borne viruses. One of the modifications is based on the stability of antigens at pH 9.0 and 1°-2°C and on the possibility of incubation of antigen-antibody mixtures for at least 24 hours. The other modification consists of a simplified method for preparing sera for the tests. The changes in technic have resulted in increase in the sensitivity of the test with no loss in specificity.
Abstract PL04-05: Vitamin D: Panacea or a Pandora's box for prevention?

Widespread interest in the possible preventive role of vitamin D against cancer emerged from ecological studies of the association between latitude and cancer mortality, in‐vitro studies of the effects of vitamin D on proliferation and apoptosis, and presence of vitamin D receptors in many tissues. Observational studies of colorectal cancer provide the most promising data supporting a potential preventive benefit for vitamin D but this effect, so far, is not supported by results from randomized trials. Observational studies for other common cancers such as prostate and breast provide little support for a significant preventive effect of vitamin D. The Cohort Consortium Vitamin D Pooling Project of Rarer Cancers (VDPP) is a consortial effort including 10 prospective cohorts from the United States, Finland and China to examine the association between concentrations of 25‐hydroxyvitamin D (25(OH)D) and risk of seven types of rarer cancers: endometrial, esophageal, gastric, kidney, non‐Hodgkin9s lymphoma, pancreatic and ovarian. No associated benefit, and potential harms, were observed including confirmation of prior reports of an increased risk of pancreatic cancer with higher concentrations of 25(OH)D. The association between mortality and 25(OH)D concentrations was examined in the Third National Health and Nutrition Examination Survey (NHANES III). The mortality rate ratio was statistically significantly higher for those with vitamin D concentrations in the deficient range, defined as 124nmol/L). Results suggest that caution should be exercised in using very high dose vitamin D supplementation in prevention trials that may result in high concentrations of vitamin D (>100nmol/L). Citation Information: Cancer Prev Res 2010;3(1 Suppl):PL04-05.
Ceftazidime-induced hemolysis in a patient with drug-dependent antibodies reactive by immune complex and drug adsorption mechanisms.

A 35-year-old woman developed acute intravascular hemolysis within five days of beginning a course of ceftazidime. The direct antiglobulin test became strongly positive with both anti-IgG and anticomplement. The serum contained an antibody that, in the presence of ceftazidime, sensitized unmodified reagent cells with IgG and complement (immune-complex type). The serum also agglutinated ceftazidime-pretreated cells at room temperature and 37 °C (drug-adsorption type). Retrospective testing disclosed that the drug adsorption antibody, which had been present before the current course of antibiotics, was not demonstrable during the hemolysis. The reactivity of the immune complex antibody, which developed by the second day of ceftazidime, paralleled the degree of hemolysis and the strength of the direct antiglobulin test. The authors believe that this patient had two separate ceftazidime-dependent antibodies and that the antibody reactive by immune complex mechanism mediated an episode of acute intravascular hemolysis.
Note on Pohlke's Theorem

(1937). Note on Pohlke's Theorem. The American Mathematical Monthly: Vol. 44, No. 4, pp. 234-234.
Toxicant exposure from smoking a little cigar: further support for product regulation.

Background Although numerous studies have documented the prevalence and increasing use of little cigars and other cigar products, the present study is the first direct, head-to-head laboratory comparison of little cigar and cigarette smoking. The study addressed a fundamental objective to compare exposure and use characteristics of little cigar and cigarette smoking. Methods Smoking patterns, toxicant exposure and subjective measures were collected and analysed in 21 adults after smoking a little cigar (Winchester) and a cigarette (own brand). Participants were dual users of little cigars and cigarettes. Results Similar to cigarettes, little cigars delivered substantial nicotine and relatively more carbon monoxide. Puff volume, puff duration and time to smoke were significantly greater after cigarettes, but the temporal pattern of smoking more intensively at the beginning was similar in little cigars and cigarettes. Both little cigars and cigarettes reduced urge to smoke. Participants consistently mentioned that the lower cost of little cigars was a reason for initiation and continuation of their use. Conclusions The results support the notion that regulation of little cigars is appropriate in light of public health considerations.
Comparative Evaluation of Four Real-Time PCR Methods for the Quantitative Detection of Epstein-Barr Virus from Whole Blood Specimens

Monitoring of Epstein-Barr virus (EBV) load in immunocompromised patients has become integral to their care. An increasing number of reagents are available for quantitative detection of EBV; however, there are little published comparative data. Four real-time PCR systems (one using laboratory-developed reagents and three using analyte-specific reagents) were compared with one another for detection of EBV from whole blood. Whole blood specimens seeded with EBV were used to determine quantitative linearity, analytical measurement range, lower limit of detection, and CV for each assay. Retrospective testing of 198 clinical samples was performed in parallel with all methods; results were compared to determine relative quantitative and qualitative performance. All assays showed similar performance. No significant difference was found in limit of detection (3.12–3.49 log10 copies/mL; P = 0.37). A strong qualitative correlation was seen with all assays that used clinical samples (positive detection rates of 89.5%–95.8%). Quantitative correlation of clinical samples across assays was also seen in pairwise regression analysis, with R2 ranging from 0.83 to 0.95. Normalizing clinical sample results to IU/mL did not alter the quantitative correlation between assays. Quantitative EBV detection by real-time PCR can be performed over a wide linear dynamic range, using three different commercially available reagents and laboratory-developed methods. EBV was detected with comparable sensitivity and quantitative correlation for all assays.
Demonstration of C5 cleaving activity in bronchoalveolar fluids and cells: a mechanism of acute and chronic alveolitis.

Recently, we have demonstrated that preformed chemotactic fragments derived from C5 (C5fr), when instilled intratracheally, induce an intense acute alveolitis. An intense intrapulmonary inflammatory reaction, characterized by accumulation of large numbers of neutrophils in the alveolar spaces, also resulted from intratracheal instillation of purified human C5. Since purified C5 does not induce PMN chemotaxis in vitro and presumably native C5 is not phlogistic in vivo, a mechanism for C5 cleavage productive of chemotactic fragments may be operative within the lung. To explore the possibility that pulmonary-mediated fragmentation of C5 occurred, both in vitro and in vivo studies were undertaken. As described in this paper, extensive cleavage of 125I-labeled C5 was demonstrated in the bronchoalveolar lavage fluids (BALF) of hamster lungs previously instilled with 125I-labeled C5. In vitro incubation of 125I-labeled C5 with normal hamster lung lavage components, cells, and lavage fluid also cleaved 125I-labeled C5. Bioassay of such in vitro reactions also revealed potent chemotactic activity for polymorphonuclear leukocytes. A potent C5-cleaving activity was detected in fluid of normal bronchoalveolar lavage (BAL) recovered from normal hamster lungs. This BALF "enzyme activity" selectively cleaved C5 in vitro, producing potent C5-related chemotactic fragmentation products, but it did not fragment C3 nor did it produce C3 chemotactic factors in vitro. Cleavage of C5 by alveolar macrophages that produces chemotactic factors has previously been attributed to an acid protease of lysosomal origin. This "enzyme activity" is apparently distinct from elastase, collagenase, and trypsin since it is not inhibited by alpha 1-antitrypsin. In separate studies, we have recently demonstrated the ability of isolated lung cells to synthesize and secrete C3 and C5 in vitro. Thus, these studies suggest that the lung may intrinsically have the capacity to regulate inflammatory reactions by the localized production of both complement components (C3 and C5) as well as complement-activating systems (e.g., C5-cleaving activity of BALF).
Immunologic findings in patients receiving methyldopa: a prospective study.

Abstract Among 71 hypertensive patients (33 Caucasian, 38 Negro) treated with methyldopa, 15 had positive direct antiglobulin (Coombs) tests. Four of these were of the IgG type, and all 4 occurred in Caucasian patients who had low levels of acetyl transferase. Eleven were of the non-IgG (complement) type and were observed in both Negro and Caucasian patients. None of the positive antiglobulin reactions was associated with changes in plasma hemoglobin levels or hemoglobin-binding capacities suggestive of hemolysis. Varied immunologic abnormalities outside the erythrocyte autoantibody system were also noted. ANA (autinuclear antibodies) were present in 53 per cent of the tested patients, elevated levels of IgG, IgA, or IgM immunoglobulins in 46 per cent, rheumatoid factor in 18 per cent, and LE cells in 4 per cent. Fourteen patients had typical and 2 had possible atypical hydralazine toxicity before or during treatment with methyldopa. Eight of them had positive antiglobulin tests, and for 3 they were of the IgG type. All of the hydralazine-toxic patients had ANA, and two thirds of them had elevated levels of IgG, IgA, or IgM immunoglobulins.
Kinship Family Relatedness, Nuclear Family Contact, and Social Support Among Foster Youth

Using a sample of 16-year-old youth placed with kinship foster families in California, the current study examines the relationship between kinship foster family structure and foster youth's biological family contact and support. Latent class analysis was used to examine differences in family structure based on the relatedness between foster youth and other members of the kinship family household. Subsequently, the respective relationships among household structure and foster youths' characteristics, experiences, and biological family contact and support were examined. We find that the kinship families serving foster youth are represented by four distinct household types, including sibling and grandparent households. Kinship family household type is found to be statistically significantly associated with youths' contact with siblings, closeness to caregivers, and perceived social support. Implications for kinship foster family scholarship are discussed.
Henry VI, Part Two

In 2 Henry VI the violence escalates into madness and butchery. Although the ironies turn sardonic and prophetic in the last act of Part 1, the memory of the brave Talbots and the comic relish of Joan’s exposure and condemnation provide enough heroism and laughter to keep the darkness of history from completely engulfing that play. Part 2 in contrast becomes considerably more savage, as Shakespeare fills the unfolding tragedy of Henry’s reign with deaths more gruesome, conspiracies more vicious, parodies of chivalry more grotesque and farcical, lords more ruthlessly ambitious, and politics more unredeemable. Except perhaps for the increasingly ineffectual king, pushed even further towards the margins of history, none of the characters is capable of enlisting the audience’s sympathy for more than a moment; seldom do we become more than spectators of this horror show of bloody self-seeking among the predators in this jungle beyond the machiavellian landscape of Part 1. Humphrey Duke of Gloucester wishes to see himself as the loyal counsellor to the king, dispensing justice in an impartial manner, yet his “humanist” judgments are undercut by the triviality of the cases, and his continuing battle with great-uncle Beaufort, the Bishop of Winchester now Cardinal, also undermines his credibility.1 Alexander Iden, loyal squire and conqueror of Jack Cade, and Lord Say, another humanist jurist, are totally representative figures, performing their brave resistance to anarchy briefly before they disappear from the plot. The play ends with York and his three sons — and the “law” of the scabbard for which they stand — in the ascendancy.
Efficient score-based Markov Blanket discovery

In a Bayesian Network (BN), the Markov Blanket (MB) of a target node consists of its parents, children, and spouses, and the target node is independent of all other nodes given its MB. Finding the MB has many applications, including feature selection and BN structure learning. We propose two new Markov Blanket discovery algorithms, score-based Simultaneous Markov Blanket discovery ( S 2 TMB) and its more efficient variant, S 2 TMB+, to improve the efficiency of existing score-based MB learning algorithms. The proposed methods remove the necessity of enforcing the commonly used symmetry constraint by exploiting the coexistence property between spouses and descendants of the target node. S 2 TMB and S 2 TMB+ achieve comparable accuracy and better efficiency than state-of-the-art score-based methods. S 2 TMB and S 2 TMB+ are proven sound and complete under one conjecture. Empirical results on standard MB discovery datasets demonstrate the superior performances of S 2 TMB and S 2 TMB+. We introduce a new score-based Markov Blanket Discovery algorithm and its variants.We show a coexist property between false positive PC nodes and spouses in the score-based MB discovery approach.The new algorithms improve the efficiency over the state-of-the-art score-based algorithm.The new algorithms are proven sound and complete under one conjecture.
A Macintosh-II CAMAC multi-parameter data acquisition system for nuclear physics experiments

An Apple Macintosh-II CAMAC data acquisition system has been developed based on a Nubus crate controller with custom drivers and display software written in C. This system provides much enhancement performance (to several events/sec) relative to GPIB or RS232-based CAMAC systems. The software provides a user-friendly multiwindow environment with pull down menus, multiparameter grating, and event-mode recording. The MAC-II system has been effectively utilized in a number of experiments such as a search for cold-fusion from Ti+D/sub 2/ loading (and unloading) at cryogenic temperatures. >
Security of Compressing Encrypted Sources

When transmitting redundant data over an insecure channel, it is customary to first compress the data and then encrypt it. Johnson et al have investigated a cryptosystem where the order of these steps is reversed, and they have shown that this reversal is possible. We formally study the security of the encrypt-then-compress cryptosystems and show that the compression does not compromise the security of the system in both the information theoretic case (perfectly secure encryption) and the complexity theoretic case (computationally secure encryption).
Modal analysis of anti-resonant hollow core fibers

We show the exploration of higher order core mode content in various designs of anti-resonant hollow core fiber using spatially and spectrally resolved imaging.
Stable colloids in molten inorganic salts

A colloidal solution is a homogeneous dispersion of particles or droplets of one phase (solute) in a second, typically liquid, phase (solvent). Colloids are ubiquitous in biological, chemical and technological processes, homogenizing highly dissimilar constituents. To stabilize a colloidal system against coalescence and aggregation, the surface of each solute particle is engineered to impose repulsive forces strong enough to overpower van der Waals attraction and keep the particles separated from each other. Electrostatic stabilization of charged solutes works well in solvents with high dielectric constants, such as water (dielectric constant of 80). In contrast, colloidal stabilization in solvents with low polarity, such as hexane (dielectric constant of about 2), can be achieved by decorating the surface of each particle of the solute with molecules (surfactants) containing flexible, brush-like chains. Here we report a class of colloidal systems in which solute particles (including metals, semiconductors and magnetic materials) form stable colloids in various molten inorganic salts. The stability of such colloids cannot be explained by traditional electrostatic and steric mechanisms. Screening of many solute-solvent combinations shows that colloidal stability can be traced to the strength of chemical bonding at the solute-solvent interface. Theoretical analysis and molecular dynamics modelling suggest that a layer of surface-bound solvent ions produces long-ranged charge-density oscillations in the molten salt around solute particles, preventing their aggregation. Colloids composed of inorganic particles in inorganic melts offer opportunities for introducing colloidal techniques to solid-state science and engineering applications.
Material Manipulations: Beads and Cloth in the French Colonies

Few can deny the impact that European-manufactured material had in the history of colonization of the Southeastern United States. Objects produced in Europe for trade with the New World, such as iron knives, copper kettles, wool cloth, yarn and blankets, glass beads, and silver jewelry, made their way into Native hands and transformed the lives and economies for many people living in the New World (Bradley, 2007; Calloway, 1997:42–45; Waselkov, 2004). Archaeological focus in recent decades on the production of commodities for the growth of mercantile economies in North American colonies has given rise to more textured interpretations of the social lives of objects in colonial contexts, not only in the Southeastern United States, but throughout colonial North America (Appadurai, 1986; Wolf, 1982; see also Given, 2005; Gosden, 2004; Lightfoot, 2004; Nassaney and Brandao, this volume; MacLean, this volume; Silliman, 2005; Thomas, 1991). In the French colony of Louisiana, which is the context for this discussion, Native and French individuals integrated newly acquired items into daily practices, putting them into use in households and communities, animating them and infusing them with meaning.
Materials Knowledge Systems in Python—a Data Science Framework for Accelerated Development of Hierarchical Materials

There is a critical need for customized analytics that take into account the stochastic nature of the internal structure of materials at multiple length scales in order to extract relevant and transferable knowledge. Data-driven process-structure-property (PSP) linkages provide a systemic, modular, and hierarchical framework for community-driven curation of materials knowledge, and its transference to design and manufacturing experts. The Materials Knowledge Systems in Python project (PyMKS) is the first open-source materials data science framework that can be used to create high-value PSP linkages for hierarchical materials that can be leveraged by experts in materials science and engineering, manufacturing, machine learning, and data science communities. This paper describes the main functions available from this repository, along with illustrations of how these can be accessed, utilized, and potentially further refined by the broader community of researchers.
Feminist Jewish Thought as Postliberal Theology

This essay considers feminist Jewish thought as a contribution to postliberal theology, insofar as it shares postliberal theology's emphasis on the sociality of reason and of revelation. In particular, the essay focuses on the authority of halakhah, or Jewish law, in the work of Judith Plaskow, Rachel Adler, and Tamar Ross, and it highlights the way that each “goes social” in her account of that authority. Like other forms of postliberal theology, feminist Jewish thought tends to emphasize the relationships and social practices that constitute a form of life and which make norms and laws authoritative for the people who participate in that form of life. Then, the essay turns to the ethical implications of those relationships and social practices, through an analysis of Plaskow and Adler's accounts of authority in human and human-divine relations. For each of these figures, given the sociality of reason and revelation, relationships among knowers ought to be characterized by reciprocal recognition and accountability.
An easy miss: aortic dissection in a ‘healthy’ male

Aortic dissection is an uncommon cause of chest discomfort that can be rapidly fatal without early diagnosis and prompt treatment. In this report, we present a man with no risk factors who presented with chest discomfort not typical of a dissection, absent pulse and blood pressure differential and a normal chest radiograph. He eventually was diagnosed with an extensive Type-A aortic dissection. We discuss diagnostic clues, classification of aortic dissection and possible treatment options.
Los procedimientos de ruptura en " el cruce sobre el niagara " de alonso alegria

La escritura de esta pieza se desarrolla en discurso lineal siguiendo la forma del teatro aristot6lico, ya que cada escena estA en funci6n de la siguiente y el suspenso se va creando en relaci6n con el desenlace.l Ademas, existe inicialmente la cuarta pared, propia al teatro aristot6lico. Sin embargo, en las escenas quinta y sexta se derrumba esa pared y el filo del escenario y el puiblico pasan a integrar el juego dramatico. Estos procedimientos de ruptura se presentan en casi todos los niveles de la obra, desde el lenguaje hasta la inscripcion polis6mica que se deriva de la escritura. Con solo dos personajes y con gran economia de signos linguisticos y recursos escenicos, Alegrfa creo una obra que de acuerdo a Isadora Aguirre "logro plasmar en forma luminosa . . . un mensaje tan optimista y trascendente . . . del hombre que se embarca en una idea, de dos hombres o de la humanidad unida en actitud creadora.2" Es diffcil clasificar esta pieza, pues comienza como teatro de tipo hist6ricodocumental y termina en un teatro de lo maravilloso. Para alcanzar este efecto en El cruce sobre el Niagara,3 Alegrfa utiliz6 consistente y acertadamente las t6cnicas de ruptura mencionadas anteriormente. En este trabajo, propongo aislar y analizar estos procedimientos en sus elementos linguisticos e inscriptivos. La pieza comienza con la sala y el escenario a oscuras y alguien lee como de una enciclopedia, los datos biograficos de Blondin, equilibrista famoso de fines del siglo XIX. De este nivel objetivo se pasa a un nivel subjetivo cuando Carlo, un joven de dieciocho anios, llega a Blondin con un desaffo y una promesa: Blondin podrfa, con entrenamiento ffsico y concentracion mental rigurosos, ser capaz de caminar en el aire "sin alambre, sin p6rtiga, sin peso ni nada!"4 El equilibrista altera su actitud socarrona al percibir que Carlo no es un fanfarron fantasioso, sino un estudioso serio de las t6cnicas de equilibrio y de las leyes de gravitaci6n.
Improved ICE fraction model for l-band remote sensing

L-band radiometers are used to retrieve sea surface salinity (SSS) and study the cryosphere. At high latitudes, it is frequent that both sea ice and water are present in the sensor's field of view. Accurately characterizing the scene is crucial for oceanographic and cryospheric applications. We present a model to derive the ice fraction affecting observations by the Aquarius and SMAP radiometers and discuss the impact of different types of ice on observed brightness temperatures. Our model shows improved match between brightness temperatures and ice fraction when compared to the model used previously in the Aquarius products. We will report on the feasibility and expected accuracy for an ice correction algorithm in the SSS retrieval algorithm.
Magnetic Resonance Imaging-Guided Laser Interstitial Thermal Therapy for the Treatment of Hypothalamic Hamartomas: A Retrospective Review.

Background Hypothalamic hamartomas (HH) are rare lesions associated with treatment-resistant epilepsy. Open surgery results in modest seizure control (about 50%) but has a significant associated morbidity. Radiosurgery is limited to a subset of patients due to latent therapeutic effects. Magnetic resonance imaging-guided laser interstitial thermal therapy (LITT) offers a novel minimally invasive option. Objective To evaluate a single center's outcomes for the LITT treatment of HH. Methods We retrospectively reviewed our experience with LITT for the treatment of HH using our institution's prospectively maintained patient database. Results Eighteen patients (mean age, 21.1 yr; median age, 11 yr) underwent 21 total LITT treatments for HH. Mean follow-up was 17.4 mo. The length of stay was 1 night for 16 (89%) patients. At the end of follow-up, 11 of 18 patients (61%) had full disconnection of the HH, and 12 of 15 (80%) patients with gelastic seizures and 5 (56%) of 9 patients with nongelastic seizures were seizure free (International League Against Epilepsy Class 1). Immediate complications included a 39% (7/18) incidence of neurological deficits, including 1 case of hemiparesis. At the end of follow-up, 22% of patients (4/18) had persistent deficits. The hypothyroidism that occurred was delayed in 11% of patients (2/18), as was short-term memory loss (22%, 4/18) and weight gain (22%, 4/18). Conclusion LITT therapy for HH can achieve excellent rates of seizure control with low morbidity and a short postoperative stay in a majority of patients. Additional research is needed to assess the durability of results and the full spectrum of cognitive outcomes.
Making Everyday Interfaces Accessible: Tactile Overlays by and for Blind People

Making a physical environment accessible to blind people generally requires sighted assistance. VizLens and Facade put blind users at the center of a crowdsourced, computer-vision-based workflow that lets them make the environment accessible on their own terms.
Self-Compassion: A Potential Path to Adolescent Resilience and Positive Exploration.

The adolescent developmental stage is characterized by multiple transitions, both physiological and environmental, and physical, cognitive and socioemotional growth that often leads to both challenges and opportunities. Developing coping strategies to contend with these challenges, such as strengthening resilience and being open to new experiences, can potentially facilitate traversing this developmental period with greater ease. Although previous research has supported the premise that self-compassion buffers the negative effects of these emotional challenges, little research to date has examined the link between strengths-based attributes such as resilience and curiosity/exploration (i.e., being open to and embracing new experiences) and self-compassion, and whether age or gender moderates these relationships. As such, the purpose of this study was to explore these relationships among a large adolescent sample. Results of 786 public school adolescents and 271 private school adolescents (68% white, 65% female, Mage = 15.6) who responded to questions in an online survey indicated that self-compassion was positively associated with both curiosity/exploration and resilience, and gender moderated the relationship between self-compassion and resilience such that this association was stronger among males than females. Age did not moderate the relationship between self-compassion and either resilience or curiosity/exploration, indicating that self-compassion is associated with both resilience and curiosity/exploration at all ages across adolescence. Implications are that interventions that cultivate self-compassion among adolescents may strengthen resilience and curiosity/exploration, offering new and healthy ways to cope with these challenges leading to improved emotional well-being.
Informed Consent and the Right to Refuse Treatment

The increasing rejection of paternalistic approaches to medical care and the growing stress on patient autonomy are among factors creating many new legal obligations for physicians. Among these obligations are the requirements that cluster around the concept of “informed consent.” More and more, physicians are being required to allow their patients the opportunity to accept or reject pro-offered procedures and also, in many cases, being required to give their patients information about the procedures.
Case 1: Linear Corneal Laceration from Scissors

A 6-year old girl presented with a Zone I open globe injury of the right eye from a pair of scissors. Initial evaluation at an outside hospital was notable only for an irregularly shaped pupil, triggering transfer to MEE for further evaluation, where an open globe injury was confirmed. The patient had a 4-mm corneal laceration inferiorly. Intraoperatively iris was found to be trapped in the corneal laceration, requiring use of filtered air and an iris spatula to release the iris tissue. Immediate post-operative visual acuity was poor due to surgically-induced astigmatism from the corneal sutures. Amblyopia therapy was initiated in the post-operative period to maintain optimal visual potential while the corneal laceration healed. Sutures were removed in the operating room at 5 weeks post-operatively. Final visual acuity was 20/15 in both eyes.
Proceedings of the 2013 conference on Computer supported cooperative work

It is our great pleasure to welcome you to the 2013 ACM Computer Supported Cooperative Work -- CSCW'13. This year's conference continues its tradition of being the premier forum for research on online collaboration, social computing, and social media studies. CSCW meets a wide range of research interests, from technical communication systems building to ethnographic studies of computer-mediated collaboration in the wild. The mission of the conference is to share novel research in these domains of interest in order to advance the state of the art in CSCW. CSCW is committed to innovation in all aspects of research. This year's conference marks the second year in which the conference used a revision cycle in the paper reviewing process. The goal of this process is to increase quality of accepted papers and grow the program to better reflect the richness of our field. 390 paper submissions were received, 139 of which were accepted for publication after going through two rigorous review cycles. This year also marks the first year in which page length limits and the Papers/Notes distinction were eliminated, resulting in an overall modest increase in the length of papers. In all, the changes to the authoring and reviewing process have generated more papers of higher quality. CSCW '13 also has tracks for posters, demos, videos, workshops, panels, and a doctoral consortium, all of which are seeing tremendous participation. The workshops alone, for instance, have attracted almost 150 participants. For the first time, CSCW this year will have an open format "unconference" track where attendees can explore ideas in greater depth. We will also have a fitness track to start each day with some collaborative healthy activity. In addition to the stellar technical program, CSCW'13 hosts two exciting keynote speakers, Ron Burt and Jascha Franklin-Hodge. Ron will open the conference with a discussion of his research on volatility and advantage in networks, while Jascha will close the conference with an in-thetrenches look at modern digital democracy. Other highlights outside the papers program include a posters and videos reception and the main conference reception, both of which should provide time to connect with your fellow CSCW researchers.
Selective Inhibition of HDAC1 and HDAC3 Inhibits Survival of Diffuse Large Cell Lymphoma Via Epigenetic Modulation of Death Associated Protein (DAPK)

Abstract Histone deacetylases (HDACs) are key players of epigenetic regulation of gene expression and are therefore attractive targets for cancer therapy. Many epigenetic drugs including HDAC inhibitors (HDACi) have shown anti-tumor activity in several types of cancers. Recently SAHA and belinostat Pan-HDACi have been FDA-approved for the treatment of T cell lymphoma. However, the capacity of Pan-HDACi for distinguishing different classes and isoforms of HDACs is limited, and may produce profound side effects. Therefore, it is important to identify cancer-relevant HDACs to promote selective HDAC inhibition for therapy in other malignancies such as diffuse large B cell lymphoma (DLBCL), the most aggressive non-Hodgkin lymphoma. Recent studies have shown that HDAC1 (HDACs class I) are commonly overexpressed in multiple cancer types and contribute to poor overall survival. However, the role of HDAC3 is not well known. The goal of this study was to determine the mechanistic role of HDAC3 and HDAC1 in DLBCL. Immunohistochemistry performed on DLBCL tumors (n=29) demonstrate 42% positivity for HDAC3 and 100% positivity for HDAC1. Ectopically expressed HDAC3 led to increased thymidine uptake, whereas HDAC3 knockdown using siRNA led to a significant decrease in thymidine uptake (p In summary, our study provides first evidence of antitumor activity of dual HDAC3 and HDAC1 targeted agent therapy in DLBCL patients. Moreover, we have identified epigenetic modulation of DAPK as potential modulator of cellular response to HDAC1/HDAC3 dual inhibition. This study suggests for further clinical trials and/or development of selective inhibitors of HDAC3 or HDAC1/HDAC3 in DLBCL patients. Disclosures No relevant conflicts of interest to declare.
Efficient oxidative desulfurization using a mesoporous Zr-based MOF

Abstract NU-1000 was synthesized and used as a catalyst in oxidative desulfurization (ODS) of model fuel. The oxidation of dibenzothiophene was studied to explore the effect of different reaction parameters (temperature, time, catalyst and oxidant loading) on the ODS performance. Under the optimized conditions, the conversion of dibenzothiophene reached 100% within 180 min. The removal of other organosulfur compounds, 4,6-dimethyldibenzothiophene, 3-methylbenzothiophene, and benzothiophene, was also examined. It was found that the reactivity is highly related to the structure of the compounds. The NU-1000 exhibited excellent stability in the reaction system and can be reused for four cycles without obvious loss of activity. The high efficiency and robustness render NU-1000 promising potential in the application of deep desulfurization of fuels.
Alliance Politics Amid the BJP’s Rise: More Continuity than Change in 2019:

Pre-election alliances have long figured prominently in Indian elections. Has the politics surrounding pre-election alliances changed with the rise of the Bharatiya Janata Party (BJP)? This article...
Muscular Dystrophy: Methods and Protocols. Katherine M.D. Bushby and Louise V.B. Anderson, eds. Totowa, NJ: Humana Press, 2001, 436 pp., $99.50, hardcover. ISBN 0-89603-695-2.

My research interest, in the field of Duchenne muscular dystrophy (DMD), began ∼18 years ago. At the time, the DMD gene had not been identified, and our primary diagnostic tools were restriction fragment length polymorphism probes and creatine kinase measurements. This book is a tribute to the great progress that has been made since that time. Several of the authors have been major players in making it all possible. It is remarkable to observe how many of the scientific discoveries have had immediate impact on molecular testing and thus have benefited many families through more accurate diagnoses and counseling. …
Green sample-preparation methods using room-temperature ionic liquids for the chromatographic analysis of organic compounds

Abstract Room-temperature ionic liquids (RTILs) are novel solvents composed entirely of ions. They can dissolve a wide range of compounds, while some possess virtually no vapor pressure over a wide temperature range, and have high thermal stability, low toxicity, and low flammability, properties desirable of green solvents. Applications that take advantage for their characteristic properties are starting to appear regularly embodied in techniques, such as liquid-phase microextraction, solid-phase microextraction, and microwave-assisted extraction. In this review, we present a contemporary picture of how, where and when to use ILs in sample-preparation techniques, while recognizing limitations that inhibit their use for some applications. Since the number of potential RTILs is very large, and only a small number have been evaluated in laboratory studies, it is important not to overgeneralize on their potential as general solvents based on this small database of rather limited chemical diversity.
Digital Second Edition of Judaica Americana: A Bibliography of Publications to 1900

This dataset, extracted from Robert Singerman’s 1990 publication of Judaica Americana, contains bibliographic data of publications before the year 1900 pertaining to Jewish people, Judaism, and Jewish culture published in the United States, in any language. The data is primarily stored on the research data repository site ScholarlyCommons at the University of Pennsylvania, and it powers an Omeka site of the same name. Reuse potential of the data includes its use as a reference tool for early American Jewish history and history of the book, historical bibliometric data, book trade documentation, and as a support for the extant study of digitization efforts in research libraries.
Compact and Resilient Cryptographic Tools for Digital Forensics

Audit logs play a crucial role in the security of computer systems and are targeted by the attackers due to their forensic value. Digital signatures are essential tools to ensure the authentication/integrity of logs with public verifiability and nonrepudiation. Especially, forward-secure and aggregate signatures (FAS) offer compromise-resiliency and append-only features such that an active attacker compromising a computer cannot tamper or selectively delete the logs collected before the breach. Despite their high-security, existing FAS schemes can only sign a small pre-defined number (K) of logs, and their key-size/computation overhead grows linearly with K. These limitations prevent a practical adoption of FAS schemes for digital forensics.In this paper, we created new signatures named COmpact and REsilient (CORE) schemes, which are (to the best of our knowledge) the first FAS that can sign (practically) unbounded number of messages with only a sub-linear growth in the keysize/computation overhead. Central to CORE is the creation of a novel K-time signature COR$\mathrm{E}_{\mathrm{B}\mathrm{a}\mathrm{s}\mathrm{e}}^{\mathrm{K}}$ that has a small-constant key generation overhead and public key size. We then develop CORE-M MM that harnesses COR$\mathrm{E}_{\mathrm{B}\mathrm{a}\mathrm{s}\mathrm{e}}^{\mathrm{K}}$ via forward-secure transformations. We showed that CORE-M MM significantly outperforms its alternatives for essential metrics. For instance, CO RE-M MM provides more than two and one magnitudes faster key updates and smaller signatures, respectively, with smaller private keys. CORE-M MM also offers extra efficiency when the same messages are signed with evolving keys. We formally prove that CORE schemes are secure. Our analysis indicates that CORE schemes are ideal tools to enhance the trustworthiness of digital forensic applications.
Impact of anxiety and depression on progression to glaucoma among glaucoma suspects

Aims To assess the impact of anxiety and depression in the risk of converting to glaucoma in a cohort of glaucoma suspects followed over time. Methods The study included a retrospective cohort of subjects with diagnosis of glaucoma suspect at baseline, extracted from the Duke Glaucoma Registry. The presence of anxiety and depression was defined based on electronic health records billing codes, medical history and problem list. Univariable and multivariable Cox proportional hazards models were used to obtain HRs for the risk of converting to glaucoma over time. Multivariable models were adjusted for age, gender, race, intraocular pressure measurements over time and disease severity at baseline. Results A total of 3259 glaucoma suspects followed for an average of 3.60 (2.05) years were included in our cohort, of which 911 (28%) were diagnosed with glaucoma during follow-up. Prevalence of anxiety and depression were 32% and 33%, respectively. Diagnoses of anxiety, or concomitant anxiety and depression were significantly associated with risk of converting to glaucoma over time, with adjusted HRs (95% CI) of 1.16 (1.01, 1.33) and 1.27 (1.07, 1.50), respectively. Conclusion A history of anxiety or both anxiety and depression in glaucoma suspects was associated with developing glaucoma during follow-up.
FENAS: Flexible and Expressive Neural Architecture Search

Architecture search is the automatic process of designing the model or cell structure that is optimal for the given dataset or task. Recently, this approach has shown good improvements in terms of performance (tested on language modeling and image classification) with reasonable training speed using a weight sharing-based approach called Efficient Neural Architecture Search (ENAS). In this work, we propose a novel architecture search algorithm called Flexible and Expressible Neural Architecture Search (FENAS), with more flexible and expressible search space than ENAS, in terms of more activation functions, input edges, and atomic operations. Also, our FENAS approach is able to reproduce the well-known LSTM and GRU architectures (unlike ENAS), and is also able to initialize with them for finding architectures more efficiently. We explore this extended search space via evolutionary search and show that FENAS performs significantly better on several popular text classification tasks and performs similar to ENAS on standard language model benchmark. Further, we present ablations and analyses on our FENAS approach.
Design of X-and Ka-Band Reflectarray Antennas for Intercelestial Communication Using CubeSat Relay

This paper presents the design of reflectarray antennas operating at X- and Ka- bands with gains of 27 dBi and 34 dBi, respectively, which will be used for 3U CubeSat relay communication. The Lunar Reconnaissance Orbiter (LRO) collects around 573 GB of data per day and the data is sent to the ground station (WS1) located in White Sands, New Mexico [1]. The LRO communicates with the earth station an average of 4 times per day throughout the year [2]. The LRO has several instruments in the lunar orbit, ranging from passive imagers to an active altimeter, as well as a synthetic aperture radar [2]. There is a growing need to transfer more data to the earth station for future missions. In order to accomplish this goal, we propose to use a CubeSat relay between earth and the moon orbiter. This CubeSat will communicate with the deep space network (DSN) instead of communicating with WS1 and this will help in improving the connection time between the moon orbiter and ground station. The data rate of the proposed method would be 4.5 Mbps with binary phase shift keying (BPSK) modulation.
Fourier Continuation Discontinuous Galerkin Methods for Linear Hyperbolic Problems.

Fourier continuation is an approach used to create periodic extensions of non-periodic functions in order to obtain highly-accurate Fourier expansions. These methods have been used in PDE-solvers and have demonstrated high-order convergence and spectrally accurate dispersion relations in numerical experiments. Discontinuous Galerkin (DG) methods are increasingly used for solving PDEs and, as all Galerkin formulations, come with a strong framework for proving stability and convergence. Here we propose the use of Fourier continuation in forming a new basis for the DG framework.