cssi/SciSciGPT-SciSciNet huggingface dataset:
Diagnosis and treatment of lipid disorders

A brief summary of the revised NCEP guidelines for the detection, evaluation, and treatment of high blood cholesterol levels in adults is presented. The major changes in the current guidelines are the inclusion of three categories of CHD risk, one for secondary prevention and two for primary prevention based upon a combination of LDL-c levels and the number of other risk factors. Age and gender are now considered in the determination of risk factors. There is more emphasis on the treatment of postmenopausal women and individuals 65 years of age or older and less emphasis on drug treatment in younger patients. HDL-c measurements are now routine in screening in the clinical setting and drugs that both lower LDL-c and increase HDL-c levels can be considered in high risk patients. According to the current guidelines, approximately 29% of the adult population should receive dietary therapy and approximately 7% may be candidates for drug therapy.
Allelic exclusion of light chain allotypes in rabbit IgM cold agglutinins.

SummaryThe IgM cold agglutinins were produced by intravenous injection of heat killed L. monocytogenes 4b into rabbits heterozygous (b4b5) for the light polypeptide chains of immunoglobulins. The radiolabeled cold agglutinins were analyzed for the b4 and b5 allotypes. The percentage of b4 and b5 light chains precipitable was independent of the order of precipitation with anti-b4 and anti-5 indicating that the cold agglutinin IgM molecules carry either the b4 or b5 light chain but not both.
Sulfhydryl Factors in Degradation of lnsulin-l131 by Liver Extracts.∗

Summary1. Glutathione degrades in-sulin-l131 and renders it more soluble in tri-chloroacetic acid. Evidence is presented that this is not the result of direct deiodination. 2. Rat liver extracts, even after exposure to a boiling water bath, can degrade insulin-l131. This heat stable activity could be explained by the presence of sulfhydryl compounds in liver. 3. Reductive as well as proteolytic processes must be considered when analyzing the degradation of insulin by crude liver extracts.The authors are indebted to Miss Ruth Miller for valuable technical assistance.
Gender and the Military Profession Early Career Influences, Attitudes, and Intentions

As increasing numbers of women are recruited into the U.S. Navy, retention of women (especially in combat occupational specialties) lags behind men. Data indicate that women and men leave the Navy ...
Optimal dynamic allocation of mobile plants to monetize associated or stranded natural gas, part II: Dealing with uncertainty

Abstract Using the Bakken shale play as a case study, the previous part of this two-part series demonstrated how small-scale mobile plants could be used to monetize associated or stranded gas effectively. Here, we address the issue of uncertainty in future supply, demand and price conditions. To this end, we modified our multi-period optimization framework to a stochastic programming framework to account for various scenarios with different parameter realizations in the future. The maximum ENPV (expected net present value) obtained was $2.01 billion, higher than the NPV obtained in the previous part. In addition, the value of the stochastic solution was 0.11% of the optimal ENPV, indicating that the flexible nature of mobile plants affords them a great advantage when dealing with uncertainty.
Properties of the Frequency–Amplitude Curve

The frequency–amplitude (F-A) curve has been proposed to characterize the electromechanical oscillation frequency of a single-machine-infinite-bus (SMIB) system considering nonlinearity of the swing equation. For a multi-machine system, the F-A curve regarding one oscillation mode is a projection of the system trajectory between the stable equilibrium point and the stability boundary onto the F-A plane. This letter provides rigorous proofs of six general properties of the F-A curve.
Enterprise Financial Strategic Management Research under the Perspective of Core Competitiveness

With the development of economic globalization,the competition among enterprises increases fiercely.The core competitiveness of enterprise becomes a driving force for sustainable development in the international market,and enterprise financial strategic management plays an increasingly important role in the enhancement of the core competitiveness of enterprise.This paper raises some strategies and suggestions in the financial strategic management based on the perspective of core competitiveness of enterprise.
Reliability analysis for shock resistance ability of shipboard equipments

The shock resistance ability of marine equipments should be determined during design and optimization phases of ship systems.Considering various stochastic factors affecting shock response of equipments,their shock resistance ability is of randomness.Here,the analysis method to obtain shock resistance ability was studied based on reliability theory.The shock response prediction model of equipments was established with a neural network algorithm.Taking a typical marine equipment as a studying object,the statistical characteristics of its shock resistance ability were analyzed utilizing Monte-Carlo Method.The proposed analysis method and the results could be a reference for ship system shock resistance design and assessment.
Investigation and Analysis on Adverse Skin Reactions to Cosmetics in Community Residents

[ObjectiveTo take a pilot study on the adverse skin reactions to cosmetics in the 20-59 years old people in Shanghai and analyze their characteristics,in order to find out the target population and provide the basis for further study.[Methods] Through stratified random sampling,1 200 people between 20 and 59 years old were recruited and answered the questionnaires for the information about adverse skin reactions to cosmetics,and then the data were arranged and analyzed.[Results] A total of 1 164 valid questionnaires were collected,in which 10.7% of respondents experienced adverse skin reactions to cosmetics over their lifetime,5.07% of them experienced adverse skin reactions to cosmetics in the preceding year.In the proportion of the adverse skin reactions to cosmetics,no difference was presented between the age groups,but significant difference existed between men and women of the 20 to 29 age group,30 to 39 age group and overall(20 to 59 years old).According to self-judgment of the respondents to determine their skin sensitivity,adverse skin reaction rate in the respondents with sensitive skin was higher than those with non-sensitive skin.The respondents with allergic history had a higher incidence rate of adverse skin reactions to cosmetics than those with no allergic history.[Conclusion] The frequency of the adverse skin reactions to cosmetics in general population according to this study is lower than that reported in foreign countries.The proportion of the people with sensitive skin might affect the frequency of the adverse skin reactions to cosmetics,and so does the proportion of the people with allergic history.
Earthquake Response Analysis of Liquified Natural Gas (LNG) Prestressed Storage Tank with Rubber Interlayer Seismic Isolation

Rubber interlayer was used as the seismic isolation of LNG storage tank,which was taken the finite element analysis before and after seismic isolation to earthquake response respectively,Before and after seismic isolation the earthquake response of LNG storage tank's outer wall are calculated under El Centro Wave,Taft Wave and Tianjin Wave. the modality,shift and acceleration are analyzed comparatinely,then the rubber interlayer seismic isolation's seismic isolation effect to LNG storage tank is obtained.
Partners at work. Catholic social teaching demands that managers respect workers' rights.

For almost 100 years Catholic social teaching has demanded that workers be treated in accord with their dignity as persons created and loved by God. Numerous papal encyclicals, a statement by the 1971 Roman Synod of Bishops, and the U.S. bishops' 1986 pastoral letter all insist on workers' rights to just wages, healthful working conditions, appropriate ways of participation and freedom to form or join unions. Throughout this century the Church has taught that a just wage should provide workers and their families "a standard of living in keeping with the dignity of the human person." Just compensation should also include provisions for adequate healthcare, security for old age or disability, unemployment compensation, and other benefits. Workers should also be able to participate as fully as possible in the enterprise they are a part of. "Each person," Pope John Paul II has written, "is fully entitled to consider himself a part owner of the great workbench at which he is working with everyone else." Finally, Catholic social teaching has consistently defended the rights of all people to form or join unions. Although the existence of this right does not oblige Catholic institutions to give up what they perceive to be their own interests, it does oblige them to avoid adopting an adversarial stance toward unions and to openly acknowledge their employees' right to unionize.
Interdisciplinary Team Collaboration between Software Engineers and Technical Communicators

Software development is a creative process that involves stakeholders from various disciplines. This interdisciplinary collaboration can bring benefits and possible success to product design and development, but can also create many challenges for team collaboration. We studied the interdisciplinary collaboration in software development projects by students in Computer Science (CS) and Humanities (HU). Sixty-four undergraduate students from the two disciplines worked together to develop citizen science applications for smart phones. The process included requirement gathering, interface design, implementation and evaluation. We investigated their collaboration through surveys, interviews, identified issues and delineated causes for failures in the collaboration. The results of our study help to explain the interdisciplinary collaboration in software development and how to improve on it.
MBSE-driven visualization of requirements allocation and traceability

In a Model Based Systems Engineering (MBSE) infusion effort, there is a usually a concerted effort to define the information architecture, ontologies, and patterns that drive the construction and architecture of MBSE models, but less attention is given to the logical follow-on of that effort: how to practically leverage the resulting semantic richness of a well-formed populated model to enable systems engineers to work more effectively, as MBSE promises. While ontologies and patterns are absolutely necessary, an MBSE effort must also design and provide practical demonstration of value (through human-understandable representations of model data that address stakeholder concerns) or it will not succeed. This paper will discuss opportunities that exist for visualization in making the richness of a well-formed model accessible to stakeholders, specifically stakeholders who rely on the model for their day-to-day work. This paper will discuss the value added by MBSE-driven visualizations in the context of a small case study of interactive visualizations created and used on NASA's proposed Europa Mission. The case study visualizations were created for the purpose of understanding and exploring targeted aspects of requirements flow, allocation, and comparing the structure of that flow-down to a conceptual project decomposition. The work presented in this paper is an example of a product that leverages the richness and formalisms of our knowledge representation while also responding to the quality attributes SEs care about.
Ice Hockey Injuries

The School of Public Health Institute for Athletic Medicine, and Departments of Orthopedic Surgery and Biomechanical Engineering, University of Minnesota, Minneapolis, MN, conducted an epidemiological study of ice hockey injuries among 12 high school varsity teams in the 1982-83 season.
Implementing consensus based distributed control in power system toolbox

This paper presents distributed control algorithm implementation in Power System Toolbox (PST). The distributed control algorithm is based on consensus and subgradient method. According this algorithm, each agent in a power system network can exchange information with their direct connected neighbors to unify all local marginal prices by consensus method. Synchronously, all agents update price information and power demands information to carry out economic operation based on subgradient method. The proposed method can realize economic dispatch and frequency regulation simultaneously. Power system toolbox (PST) is selected as the platform to implement the distributed control algorithm. The approach to implement this algorithm in PST is presented. Effect of the proposed algorithm is compared with a secondary frequency control via simulation results.
Synergistic effects in stress corrosion cracking of glass reinforced polymer composites

Abstract Synergistic effects of nitric acid exposure, elevated temperature, applied flexural stress and time were examined in the Stress Corrosion Cracking (SCC) of widely used unidirectional Glass Reinforced Polymer (GRP) composites. The composites were composed of two different E-CR glass fibers with a vinylester-epoxy resin as the matrix with E-glass fibers in the same matrix used for a baseline comparison. SCC damage, as measured by the number of fiber cracks, amount of metallic ion leaching from the fibers, and the reduction of residual flexural strength and stiffness properties of the composites, affected the composites differently depending on their composition. As expected, the E-CR composites greatly outperformed the E-glass composites under all conditions. Long term exposure of the E-CR composites did not greatly increase the amount of stress corrosion fiber damage; instead, interface issues and matrix decomposition led to reduced mechanical properties over extended periods of time. The synergistic effect of the combined testing conditions was found to be much stronger in the E-glass than the E-CR glass composites.
Plasma serpinB1 is related to insulin sensitivity but not pancreatic β‐Cell function in non‐diabetic adults

Pancreatic β ‐cell dysfunction because of reduced β ‐cell mass and function is a primary determinant in the progression of diabetes. Increase in β ‐cell mass and compensatory hyperinsulinaemia is frequently associated with insulin‐resistant states. Although the humoral factors mediating this compensatory response are unknown, serpinB1, a protease inhibitor, has recently been proposed to be one such factor. In this study, we examine the relationships between plasma serpinB1, insulin sensitivity, and pancreatic β ‐cell function in non‐diabetic individuals. 117 subjects (women, n = 50, men, n = 67; age= 37.6 ± 10.8; BMI=31.1 ± 7.7 kg/m2) underwent an insulin‐modified frequently sampled intravenous glucose tolerance test (FSIVGTT) at the NIH Clinical Research Center. Acute insulin response (AIR) and insulin sensitivity index (SI) were obtained from the FSIVGTT with MINMOD analysis. The Quantitative Insulin Sensitivity Check Index (QUICKI) was calculated from fasting insulin and glucose values. Plasma serpinB1 levels were measured using an ELISA assay. Simple linear correlation analyses were performed to evaluate the relationship between serpinB1 and measures of insulin sensitivity and β ‐cell function. Circulating serpinB1 levels were unrelated to age, sex, race, BMI, or percent body fat. SI but not AIR significantly correlated with circulating serpinB1 levels ( r = 0.23, P < 0.05). QUICKI tended to positively correlate with serpinB1 ( r = 0.16, P = 0.09). Circulating serpinB1 is directly associated with insulin sensitivity but not β ‐cell function in non‐diabetic adults. Whether this modest association plays a role in insulin sensitivity in humans remains to be clarified.
The Iron Law

Star Wars: The Old Republic and Fallen Earth are two of the many recent online gameworlds that depict disintegrating and conflict-ridden societies, in which the very legitimacy of the law is in doubt. Thus they become vehicles for critique of real modern society, and intentionally or unintentionally reflect social-scientific theories of social disorganization, institutional functionality, and the origins of law. This essay examines these examples in terms of the Iron Law of Oligarchy proposed a century ago by Robert Michels, and related classical theories that either contradict or extend it.
Nutrition, Lifestyle, and Hypertension

Abstract Hypertension is a major risk factor for coronary heart disease, stroke, and premature death and a leading risk factor for global disease burden. Prevalence for those 18 years and older in the United States has remained around 29% since 1999 with little improvement. Further, approximately one-third of U.S. adults have prehypertension, which is also associated with a graded, increased risk of cardiovascular disease and progression to hypertension. The overall evidence that diet modification can prevent and treat hypertension is strong. The current national guideline of lifestyle modification for blood pressure control includes the DASH eating pattern, sodium reduction, weight loss, increased physical activity, and moderate consumption of alcohol. Concurrent adherence to several recommendations is likely to hold the greatest promise for preventing and treating hypertension and has been shown to be feasible. In addition to addressing unresolved nutritional hypotheses, future research should focus on strategies to motivate and maintain lifestyle changes long term for blood pressure control. At both the population and individual levels, success in dietary and lifestyle intervention relies on multiple levels of support ranging from clinicians to government agencies to private institutes and industries. In particular, partnering with industry to improve the nutritional quality of the food supply, such as reducing sodium, sugar, and saturated and trans fat content of processed foods, and promoting foods and nutrients consistent with the DASH dietary pattern will play a critical role in implementing dietary and lifestyle modifications. Consistent efforts to educate and promote adherence to dietary and lifestyle guidelines by dietetic and other health care professionals are also instrumental to the prevention and management of hypertension.
Nonlinear optical correlators: exploiting phase-with-constrained- magnitude filter devices

Various nonlinear mapping techniques have been investigated for exploiting the restrictive characteristics of available spatial light modulators (e.g., phase-only or binary phase-only) and/or to modify the performance of coherent optical correlators. The phasewith- constrained-magnitude filter (PCMF) is a practical complex spatial filter realizable with today’s technology. It relies on the coupling between magnitude and phase transmittance exhibited by certain types of spatial light modulators. It requires relatively little computational effort to implement, and its performance has been shown to compare quite favorably with that of phase-only filters. In this paper we review the basic PCMF concept and show how performance of the PCMF can be improved by modifying the basic PCMF algorithm in two ways: (1) by setting the magnitude transmittance of the spatial light modulator to its lowest achievable value for a chosen set of low spatial frequency components and (2) by adjusting the values of the desired spatial frequency distribution relative to the available dynamic range of the spatial light modulator. The second method, in particular, can be used to make the PCMF perform more like an inverse filter or more like a matched filter, depending on the desired results.
Efficient block preconditioned eigensolvers for linear response time-dependent density functional theory

We present two efficient iterative algorithms for solving the linear response eigenvalue problem arising from the time dependent density functional theory. Although the matrix to be diagonalized is nonsymmetric, it has a special structure that can be exploited to save both memory and floating point operations. In particular, the nonsymmetric eigenvalue problem can be transformed into an eigenvalue problem that involves the product of two matrices M and K. We show that, because MK is self-adjoint with respect to the inner product induced by the matrix K, this product eigenvalue problem can be solved efficiently by a modified Davidson algorithm and a modified locally optimal block preconditioned conjugate gradient (LOBPCG) algorithm that make use of the K-inner product. The solution of the product eigenvalue problem yields one component of the eigenvector associated with the original eigenvalue problem. We show that the other component of the eigenvector can be easily recovered in an inexpensive postprocessing procedure. As a result, the algorithms we present here become more efficient than existing methods that try to approximate both components of the eigenvectors simultaneously. In particular, our numerical experiments demonstrate that the new algorithms presented here consistently outperform the existing state-of-the-art Davidson type solvers by a factor of two in both solution time and storage.
P247 Evaluation of ABHI approved in-house continuing education program

Aim To evaluate the efficacy of continuing education credits (CEC) offered to histocompatibility technical staff. Methods In order to increase continuing education opportunities for a large laboratory staff, we applied for ABHI approval for a lecture series in 2015/2016. A variety of transplant professionals were invited to present to our staff members comprised of 15% CHT and 42% CHS. Applying for ABHI certification allowed staff members to earn.15 CEC for each of the 10 lectures in the series. Speakers included: a member of the local organ procurement organization, a nurse coordinator, laboratory staff members, transplant surgeons, oncologists and university researchers. A survey was distributed to evaluate the staff’s views on the importance and satisfaction of the lecture series. Results Staff members were able to accumulate an average of 6.9 contact hours (range 3–10 h) and earn 1.03 CEC (range.45–1.5 CEC) for the 2015/2016 ABHI approved lecture series. 76% of staff members participated in the survey. 100% of the participants responded that they gained knowledge from the presentations. The technical staff recognized the importance of continuing education by rating it 4.19 out of 5. There are many lectures given on the university campus, but 13 out of 29 respondents said that they did not attend any lectures other than those sponsored by the laboratory. The ABHI approved in-house lecture series was ranked second after ABHI approved meetings for preferred method to obtain CEC. Conclusions Applying for an ABHI approved lecture series is an efficient way to provide staff members with continuing education credits needed to maintain certification. Technical staff have an opportunity to earn over 50% of their required CEC over a three year period. Additionally, staff value continuing education as an important part of their job. The laboratory needs to make an effort to provide staff with continuing education opportunities.
Serotonin receptor and dendritic plasticity in the spinal cord mediated by chronic serotonergic pharmacotherapy combined with exercise following complete SCI in the adult rat.

Abstract Severe spinal cord injury (SCI) damages descending motor and serotonin (5-HT) fiber projections leading to paralysis and serotonin depletion. 5-HT receptors (5-HTRs) subsequently upregulate following 5-HT fiber degeneration, and dendritic density decreases indicative of atrophy. 5-HT pharmacotherapy or exercise can improve locomotor behavior after SCI. One might expect that 5-HT pharmacotherapy acts on upregulated spinal 5-HTRs to enhance function, and that exercise alone can influence dendritic atrophy. In the current study, we assessed locomotor recovery and spinal proteins influenced by SCI and therapy. 5-HT, 5-HT2AR, 5-HT1AR, and dendritic densities were quantified both early (1 week) and late (9 weeks) after SCI, and also following therapeutic interventions (5-HT pharmacotherapy, bike therapy, or a combination). Interestingly, chronic 5-HT pharmacotherapy largely normalized spinal 5-HTR upregulation following injury. Improvement in locomotor behavior was not correlated to 5-HTR density. These results support the hypothesis that chronic 5-HT pharmacotherapy can mediate recovery following SCI, despite acting on largely normal spinal 5-HTR levels. We next assessed spinal dendritic plasticity and its potential role in locomotor recovery. Single therapies did not normalize the loss of dendritic density after SCI. Groups displaying significantly atrophied dendritic processes were rarely able to achieve weight supported open-field locomotion. Only a combination of 5-HT pharmacotherapy and bike therapy enabled significant open-field weigh-supported stepping, mediated in part by restoring spinal dendritic density. These results support the use of combined therapies to synergistically impact multiple markers of spinal plasticity and improve motor recovery.
The Role of Psychosocial Factors in Chronic Obstructive Pulmonary Disease

This article reviews research documenting the role of psychosocial factors in various areas. Its goal is to highlight the importance of identifying and addressing psychosocial dysfunction in patients with chronic obstructive pulmonary disease and the benefits gained by including psychosocial interventions for patients with chronic obstructive pulmonary disease within pulmonary rehabilitation programs.
Biodegradation of Biomass—Mechanisms

The efficiency of microorganisms in the recycling of organic materials both by individual cells and by consortia,, is illustrated by their effective mineralization of resistant materials ranging from cellulose, to lignin and to novel recalcitrant xenobiotics. The mechanisms for such transformations that are gradually being unravelled, are discussed. Such understanding will permit rationale approaches for gaining greater catalytic efficiency and conversely, for development of more selective inhibition of degradative processes.
EXACT SOLUTIONS OF THE EINSTEIN VACUUM FIELD EQUATIONS IN WEYL CO- ORDINATES.

Inconsistencies inherent in the interpretation of the canonical Weyl co-ordinates in the quadratic differential form for static, axially symmetric distributions of matter in general relativity as the timet and the cylindrical co-ordinatesr,z,ϕ are demonstrated in a number of ways. The most general Weyl quadratic differential form in which the metric is a function of only the radial co-ordinate is analyzed. This solution depends upon a single parameterσ, and reasons are given for interpreting this solution as an infinite line of positive mass for 0 <σ < 1/2; a homogeneous gravitational field forσ = +1, and an infinite sheet of negative mass forσ = −1. All solutions are given which correspond to flat space, and these are used to demonstrate that if one has two Weyl potentials each corresponding to a physical system, the sum of the two potentials is not the potential corresponding to the superposition of the two physical systems.
Social Monitoring as Social Control: The Case of Drug Testing in a Medical Workplace'

While workplace drug testing has received considerable public and scholarly attention, little of this discussion has focused on the social context within which testing is likely to occur. This paper conceptualizes drug testing as social monitoring and examines testing within a framework suggested by Donald Black's theory of social control. The central idea is that the formality of social monitoring within a group is a function of its members' social status and the social distance among them. The paper evaluates this argument in one empirical setting. Analysis of data from U.S. departments of anesthesiology indicates that drug testing, an example of formal monitoring, most often emerges in a context marked by low normative respectability and a lack of intimate relationships. The paper concludes by suggesting how variations in monitoring procedures like drug testing may affect ensuing processes of social control.
The Xpert HCV Viral Load Finger-Stick point-of-care test was accurate for detecting HCV RNA.

Source Citation Lamoury FMJ, Bajis S, Hajarizadeh B, et al; LiveRLife Study Group. Evaluation of the Xpert HCV Viral Load Finger-Stick point-of-care assay. J Infect Dis. 2018;217:1889-96. 29534185
A New Generation of Ground-Based Mobile Platforms for Active and Passive Profiling of the Boundary Layer

AbstractMobile systems equipped with remote sensing instruments capable of simultaneous profiling of temperature, moisture, and wind at high temporal resolutions can offer insights into atmospheric...
Climate variability, rainfall shocks, and farmers’ income diversification in India

Abstract Rainfall in India has become much more variable as a result of global climate change. Responses to rain shocks vary depending on the level of climate variation a community experiences historically. Using data spanning three decades in 230 villages in India, I find that farmers tend to diversify their income with non-farm wage jobs in response to rainfall shocks. This diversification strategy is employed less in places with more variable historical weather as people are more adapted. As climate change causes more variable weather in the coming years, my results suggest that places with historically less variable weather may become more vulnerable in this changing climate.
Paroxysmal Cold Hemoglobinuria in an Adult with Respiratory Syncytial Virus.

Paroxysmal cold hemoglobinuria (PCH) is a rare form of cold autoimmune hemolytic anemia first discovered in the early 20th century in adults with tertiary syphilis. Today, it is more commonly seen in children as a life-threatening anemia during a viral upper respiratory tract infection (URI). Although respiratory syncytial virus (RSV) has previously been reported to cause PCH in a child, herein we present the first documented case in an adult. The Donath–Landsteiner (DL) test, the diagnostic test for PCH, was positive on two separate occasions. The patient was treated successfully with warming and avoidance of cold temperatures. To facilitate identification of this rare entity by clinicians, we include a discussion about the pathophysiology, diagnosis, and treatment of PCH.
Deans of Women and the Feminist Movement: Emily Taylor’s Activism. By Kelly C. Sartorius

As a historian of US women, when I think about higher education and advances for women, I think of the landmark legislation, Title IX of the Education Amendments of 1972. Kelly Sartorius’s study in...
“The Harz Journey”: Travelogue as Philosophical Satire

“‘The Harz Journey’: Travelogue as Philosophical Satire” offers an analysis of one of the best known stories of Heine’s Reisebilder (Travel Pictures) as a cross-generic work that mediates between travelogue, critical reflection, poetry, song, and fable. “Die Harz Journey” (“Die Harzreise”) shows how Heine’s method, while steeped in the ambivalence of satirizing Romanticism yet assuming to be its last heir, is profoundly critical, because it is systematically self-reflexive, as Heine views the subject of his writing from a distance which allows him to reassess his own position. I compare the wittily philosophical frame of this unusual travelogue to Mikhail Bakhtin’s concept of the carnivalesque, which translates the realm of abstract thought to concretely sensuous images and diverse and dynamic events. A further comparison is with the work of Jorge Luis Borges, who like Heine, delighted in an admixture of the real, the imaginary, and the arabesque.
Smart Biosensor for Rapid and Simultaneous Detection of Waterborne Pathogens in Tap Water

This paper presents a new design of a MEMS based impedance biosensor for simultaneous detection of multiple waterborne pathogens in tap water Figure 1. The testing panel includes Legionella, E. coli O157: H7 and Salmonella. The device is unique in terms of its ability to focus, concentrate a low amount of pathogens to a detectable level, and detect them using interdigitated electrode (IDE) arrays coated with specific antibody to enable detection of pathogens with high selectivity and sensitivity at a concentration as low as 3 cells/ml in 1 hour.
Power Market Model in Presence of Strategic Prosumers

Prosumers, with ability to act both as a supplier and a consumer in a power market, have received considerable attention recently. Possessing with distributed energy resources, their capability to operate in an isolated mode, shielding from the main grid, has also been promoted as a vital option to enhance the power system's resilience. One emerging concern is the prosumer's ability to manipulate the power market as a buyer or as a seller. This study vets the outcomes of a power market in presence of strategic prosumers. We formulate the optimization problem faced by the prosumers in a complementarity problem. We posit a situation in which a strategic prosumer owns a renewable unit with variant output and a dispatchable backup unit, and participates in a competitive market. The prosumer is assumed to maximize its benefit by deciding amount of power to buy from or sell into the main grid, amount of renewable power to forego consumption, and amount of power to produce from backup unit. The model is applied to a case study of the IEEE 24-bus RTS as an illustrative example. We summarize the model properties and findings in three propositions and report distributional impacts of economic rent among conventional suppliers and consumers.
Semi-supervised learning and inference in domain-wall magnetic tunnel junction (DW-MTJ) neural networks

Advances in machine intelligence have sparked interest in hardware accelerators to implement these algorithms, yet embedded electronics have stringent power, area budgets, and speed requirements that may limit non- volatile memory (NVM) integration. In this context, the development of fast nanomagnetic neural networks using minimal training data is attractive. Here, we extend an inference-only proposal using the intrinsic physics of domain-wall MTJ (DW-MTJ) neurons for online learning to implement fully unsupervised pattern recognition operation, using winner-take-all networks that contain either random or plastic synapses (weights). Meanwhile, a read-out layer trains in a supervised fashion. We find our proposed design can approach state-of-the-art success on the task relative to competing memristive neural network proposals, while eliminating much of the area and energy overhead that would typically be required to build the neuronal layers with CMOS devices.
Growth and endocrine responses of cattle to implantation of estradiol-17 beta during continuous or discontinuous grazing of high- and low-endophyte-infected tall fescue.

Forty-eight Angus x Hereford steers (initial BW = 336 +/- 8.3 kg) were used in a 56-d study to evaluate growth and endocrine responses to continuous or discontinuous grazing of high-endophyte-infected Kentucky-31 (K; > 57% infestation rate) or low-endophyte-infected Johnstone tall fescue (J; < 1% infestation rate) and implantation with 0 or 24 mg/steer of estradiol-17 beta (E2; Compudose). Steers were allotted by weight to eight 3-ha paddocks (four paddocks of each fescue variety) with six steers per paddock. Two paddocks of each variety were grazed continuously (KK and JJ), whereas steers on the remaining four paddocks were rotated every 14 d from K to J (KJ) or from J to K (JK). Three steers in each paddock were implanted with E2 on d 0. The study extended from May 25, 1988 to July 20, 1988 with steers exposed to potential heat-stress conditions for 52 d of the 56-d study. Body weights were obtained on d 0, 28, and 56, and blood samples were taken on d 28 and 56. Overall ADG, serum prolactin, and serum alkaline phosphatase activity were greater (P < .05) in JJ than in KK steers. Rotation from K to J did not increase overall ADG, prolactin, insulin-like growth factor I (IGF-I), or alkaline phosphatase activity compared with the continuously grazed KK, whereas JK steers had lower (P < .10) ADG, prolactin, and alkaline phosphatase activity than JJ steers. Estradiol-17 beta increased (P < .10) IGF-I in JJ, KJ, and JK steers but not in KK steers.(ABSTRACT TRUNCATED AT 250 WORDS)
Conductive inserts to reduce nuclear fuel temperature

Abstract In an effort to develop better performing nuclear fuels, placement of conductive inserts in nuclear fuel pellets is being considered. Conductive inserts incorporated in the fuel pellets will dissipate heat more efficiently, allowing the fuel to operate at a lower temperature while producing the same amount of power. Calculation results reported in the present paper, show that placing a 6-finned molybdenum insert in a UO2 pellet will result in an 842 C reduction of the peak fuel temperature. Likewise, placing multiple equidistantly spaced 50 μm thick molybdenum discs in a UO2 pellet will result in a 995 C reduction of the peak fuel temperature. In both cases, the volume of the insert is limited to 5% of the volume of the pellet. While these results are preliminary in scope, the impact of the reduced peak temperature on expected fuel performance warrants initiation of experimental work that will include fabrication and irradiation of these and similar fuel designs at the Idaho National Laboratory.
PRPS polymerization influences lens fiber organization in zebrafish.

Background The self-assembly of metabolic enzymes into filaments or foci highlights an intriguing mechanism for the regulation of metabolic activity. Recently, we identified the conserved polymerization of phosphoribosyl pyrophosphate synthetase (PRPS), which catalyzes the first step in purine nucleotide synthesis, in yeast and cultured mammalian cells. While previous work has revealed that loss of PRPS activity regulates retinal development in zebrafish, the extent to which PRPS filament formation affects tissue development remains unknown. Results By generating novel alleles in the zebrafish PRPS paralogs, prps1a and prps1b, we gained new insight into the role of PRPS filaments during eye development. We found that mutations in prps1a alone are sufficient to generate abnormally small eyes along with defects in head size, pigmentation, and swim bladder inflation. Furthermore, a loss-of-function mutation that truncates the Prps1a protein resulted in the failure of PRPS filament assembly. Lastly, in mutants that fail to assemble PRPS filaments, we observed disorganization of the actin network in the lens fibers. Conclusions The truncation of Prps1a blocked PRPS filament formation and resulted in a disorganized lens fiber actin network. Altogether, these findings highlight a potential role for PRPS filaments during lens fiber organization in zebrafish.
Prolonged Implantation of Sinus Devices and Implications for Chronic Rhinosinusitis: A Case Report and Review of the Literature.

Background: Implantation of sinus stents and spacers can be used as adjuvant management to maintain patency of sinuses after endoscopic sinus surgery for chronic rhinosinusitis. These implants are typically removed several weeks after surgery. We present two cases of different patients who were initially treated by different physicians and were found to have retained sinus spacers in their paranasal sinuses 6-10 years after implantation. Case Presentation: Case 1: A 40-year-old male with chronic rhinosinusitis and history of balloon sinuplasty six years prior presented with worsening symptoms of chronic rhinosinusitis refractory to medical management. He underwent revision functional endoscopic sinus surgery and was found to have retained sinus implants in the left and right frontal sinus recesses. Case 2: A 48-year-old female with long-standing chronic rhinosinusitis refractory to medical management presented after two prior sinus surgeries most recently 10 years ago. She underwent revision functional endoscopic surgery and was found to have a retained sinus implant from prior surgery in the right frontal recess outflow tract embedded within scar tissue and reactive hyperostosis. Foreign bodies from both patients were removed without complication and patients were healing appropriately in the post-operative period. Conclusions: While sinus stents and spacers can help with post-operative scarring, leaving then unmonitored and in place will eventually result in them becoming a nidus for scarring and infection. It is critical that patients are aware of any foreign bodies we place, if they need scheduled removal or routine observation, and what symptoms may indicate that they are causing a problem.
Regulation of Prdx6 by Nrf2 Mediated Through aiPLA2 in White Matter Reperfusion Injury

Hypoxia and reperfusion produces overproduction of ROS (reactive oxygen species), which may lead to mitochondrial dysfunction leading to cell death and apoptosis. Here, we explore the hypothesis that Prdx6 protects the spinal cord white matter from hypoxia-reperfusion injury and elucidate the possible mechanism by which Prdx6 elicits its protective effects. Briefly, rats were deeply anesthetized with isoflurane. A 30-mm section of the spinal cord was rapidly removed and placed in cold Ringer’s solution (2–4 °C). The dissected dorsal column was exposed to hypoxia with 95% N2 and 5% CO2 and reperfusion with 95% O2 and 5% CO2. The expression of Prdx6 significantly upregulated in white matter after hypoxia compared to the sham group, whereas reperfusion caused a gradual decrease in Prdx6 expression after reperfusion injury. For the first time, our study revealed the novel expression and localized expression of Prdx6 in astrocytes after hypoxia, and possible communication of astrocytes and axons through Prdx6. The gradual increase in Nrf2 expression suggests a negative regulation of Prdx6 through Nrf2 signaling. Furthermore, inhibition of aiPLA2 activity of Prdx6 by MJ33 shows that the regulation of Prdx6 by Nrf2 is mediated through aiPLA2 activity. The present study uncovers a differential distribution of Prdx6 in axons and astrocytes and regulation of Prdx6 in hypoxia-reperfusion injury. The low levels of Prdx6 in reperfusion injury lead to increased inflammation and apoptosis in the white matter; therefore, the results of this study suggest that Prdx6 has a protective role in spinal hypoxia-reperfusion injury.
Penetration of dipole radiation into an ENZ medium

Abstract We consider electric dipole radiation emitted near an interface with an epsilon-near-zero (ENZ) material. Such a medium is nearly impenetrable for electromagnetic plane waves, but we show that dipole radiation can penetrate deep into the medium. The radiation is represented by an angular spectrum of plane waves, and each partial wave transmits as an evanescent wave. The sum of these waves, however, is not evanescent, but decays algebraically with the distance to the interface. We have evaluated the electric and magnetic fields inside the material, and we have constructed the Poynting vector. We found that energy flows through the material, and not only in a small region near the interface. For the case of a perpendicular dipole, the magnetic field is zero, and the electric field can be obtained in closed form. We show that the electric field decays as the third power of the distance to the interface.
Tax Administration and Racial Justice: The Illegal Denial Of Tax Based Pandemic Relief To The Nation's Incarcerated

In the midst of a devastating pandemic that would sicken millions, kill hundreds of thousands, and cause widespread financial distress, Congress passed the Coronavirus Aid, Relief, and Economic Security (CARES) Act. CARES provided for the IRS to deliver up to $1,200 for adults and $500 for dependent children. It was ostensibly structured as a refundable credit to be claimed on a 2020 tax return, but with a twist. The statute authorized the IRS to pay it in advance, even to those who did not have a tax return filing obligation, and to do so as “rapidly as possible.” While there were some problems, the IRS generally did remarkably well, and within six months it had delivered about 160 million payments totaling over $270 billion.This Essay addresses one of those exceptional problems: it involves the IRS’s unexplained change in position on the eligibility of those incarcerated in our nation’s federal, state, and local prisons and jails. At first, the incarcerated, just like other Americans suffering the effects of the pandemic, received the money that they were entitled to receive under the CARES legislation. That changed. In early May of 2020, the IRS announced on its web page that those who were incarcerated were not eligible for immediate cash benefits, worked with prison officials to claw back payments it had made, and stopped in their tracks hundreds of thousands of payments that it had not yet made. By October, the government faced a complete rebuke of its policy in Scholl v Mnuchin, a class action suit that held that the IRS’s actions were contrary to law and arbitrary and capricious under the Administrative Procedure Act. By looking at the IRS actions that led to Scholl v Mnuchin, this Essay explores the relationship of tax administration and racial justice. It reveals how tax administration can normalize and reinforce patterns of racial inequality through the presence of racialized administrative burdens. Finally, this Essay then considers how the IRS’s actions with respect to restricting payments to the incarcerated population can offer lessons to minimize the risk that future IRS actions will harm people of color, especially given the IRS’s role in delivering benefits.
Word skipping in deaf and hearing bilinguals: Cognitive control over eye movements remains with increased perceptual span

Deaf readers may have larger perceptual spans than ability-matched hearing native English readers, allowing them to read more efficiently (Belanger & Rayner, 2015). To further test the hypothesis that deaf and hearing readers have different perceptual spans, the current study uses eye-movement data from two experiments in which deaf American Sign Language–English bilinguals, hearing native English speakers, and hearing Chinese–English bilinguals read semantically unrelated sentences and answered comprehension questions after a proportion of them. We analyzed skip rates, fixation times, and accuracy on comprehension questions. In addition, we analyzed how lexical properties of words affected skipping behavior and fixation durations. Deaf readers skipped words more often than native English speakers, who skipped words more often than Chinese–English bilinguals. Deaf readers had shorter first-pass fixation times than the other two groups. All groups’ skipping behaviors were affected by lexical frequency. Deaf readers’ comprehension did not differ from hearing Chinese–English bilinguals, despite greater skipping and shorter fixation times. Overall, the eye-tracking findings align with Belanger’s word processing efficiency hypothesis. Effects of lexical frequency on skipping behavior indicated further that eye movements during reading remain under cognitive control in deaf readers.