cssi/SciSciGPT-SciSciNet huggingface dataset:
The relationship between family‐of‐origin experiences and sexual satisfaction in married couples

This study examined the relationship between perceptions of family-of-origin experiences, sexual satisfaction and marital quality. The sample consisted of 3953 married couples who responded to the relationship evaluation. The results showed that more positive overall family-of-origin experiences and parent–child relationships were related to higher sexual satisfaction. Overall, family-of-origin experiences and parent–child relationships were predictive of higher sexual satisfaction; however, that relationship was significantly mediated by marital quality. There was a strong positive relationship between marital quality and sexual satisfaction. No major gender differences emerged from the findings. The results suggest that family-of-origin experiences play a key role in the sexual satisfaction of married couples, especially when mediated by marital quality, and should be considered in treatment, education and research.
No discernible effect of Mg2 + ions on the equilibrium oxygen isotope fractionation in the CO2–H2O system

Abstract Equilibrium oxygen isotope fractionation factors ( α CO 2 g – H 2 O , α HCO 3 – H 2 O and α CO 3 – H 2 O ) are fundamental geochemical parameters that characterize 18O partitioning in the CO2–H2O system. These constants were established in laboratory experiments using deionized H2O (e.g., Beck et al. (2005) and references therein). The applicability of these constants in environmental waters, including natural seawater, appears questionable due to potentially strong ionic interactions in such aqueous media. For instance, considerable portions of carbonate ions in seawater exist as cation–CO32 − ion complexes such as MgCO30. In this study, quantitative BaCO3 precipitation experiments were performed to examine the effect of Mg2 + concentrations on the oxygen isotope equilibrium between dissolved inorganic carbon (DIC) species and H2O. Our results from Mg2 +-free control experiments in which BaCO3 samples were precipitated from simple NaHCO3 solutions were in good agreement with empirical results from three independent studies and with theoretical calculations. BaCO3 precipitations from solutions with Mg2 + concentrations higher than 2.5 mM caused intolerable quantities of Mg(OH)2 co-precipitation, which interfered with δ18O measurements. Within the limit of 2.5 mM of [Mg2 +], the MgCO30 abundance in the total carbonate ions ([CO32 −]T) and [DIC] was varied over approximately 0 to 40% and 0 to 36%, respectively, by manipulating solution chemistry. Despite such chemical treatment, there was no effect of Mg2 +-addition on α BaCO 3 – H 2 O . These results suggest that the presence of Mg2 + in solutions has a negligible effect on the oxygen isotope equilibrium in the CO2–H2O system. In seawater, Mg2 + is the most important cation that forms complexes with CO32 −. Hence, if our results also hold at higher [Mg2 +] and higher ionic strength, they imply that the applicability of freshwater-based equilibrium fractionation factors is not compromised by ionic interactions in seawater.
Spectroscopic Measurements of Oxygen Saturation in the Retina

We introduce a new type of retinal oximeter able to capture multiple spectroscopic sensitive images of the retina in a single snapshot. The core of our apparatus is a multiaperture camera that can be easily interfaced with a fundus camera system. A lenslet array divides the image collected by a fundus camera into identical subimages. A bandpass filter array in front of the lens system is used to collect the subimages only at the wavelengths of interest. Two different instruments were designed based on this simple principle. The first system can collect six different images, while the second system can collect up to 18 different images in a single snapshot.
Mixed viral infections: detection and management.

An analysis was done of the incidence and nature of mixed virus infections diagnosed in the same clinical specimen from immunocompetent patients; respiratory viruses were emphasized. Few studies have addressed mixed viral infections in any systematic fashion. The relevant studies reviewed focused on clinical relationships or diagnostic methods. Data relating to multiple infections were usually derived incidentally to the purpose of the investigations. Sixty-three percent of the reports with data on mixed infections identified them in 10% of specimens that were negative for the virus targeted by one method. There was no indication that mixed infections were associated with increased disease in immunocompetent patients or in certain immunocompromised patients. Immunocompromised patients, however, appeared to have a greater incidence of multiple infections. Mixed infections of single cells also occur and may have important clinical implications relative to reactivation of latent viruses and enhanced disease. The requirement for a comprehensive strategy for viral diagnosis involving multiple techniques was indicated by these findings.
Environmental And Structural Influences On The Strategy-Making Process Of Banks

This study investigated the effects of perceived environmental dynamism, heterogeneity, and resource munificence, as well as two structural characteristicsformalization and centralizationon the strategy-making variables of assertiveness and rationality. Finding from 59 banks indicated that perceived environmental heterogeneity and munificence were both positively related to the assertiveness and rationality of strategy-making, whereas perceived dynamism was negatively related to rationality. Formalization, a structural variable, was found to contribute the most to strategy-making.
The primary-care physician and cancer detection: the role of the Pap smear.

Abstract This is a retrospective 5 year study of cancer detection in the suburban office of a primary-care physician. There were 127 diagnoses of malignancy confirmed in 5,011 patients, 65 in the reproductive system and 62 in other organ systems. More than 9,000 Pap smears resulted in the final diagnosis of carcinoma of the cervix in only seven patients, 374 curettages yielded 37 cases of endometrial carcinoma. All of these patients had Class I Pap smears preoperatively.
Chapter 17 Organ Culture of Gastric Mucosa: Advantages and Limitations

Publisher Summary The chapter describes early experience with organ culture of gastric tissue, to indicate ways in which the technique has been used to study gastric function, and to point out the kinds of investigations that are needed in the future. In recent years, in vitro techniques have been increasingly applied in efforts to examine gastric mucosal function under more rigidly controlled conditions. The chapter discusses methods for organ culture of fetal stomach, adult fundic mucosa, and adult antral mucosa. Although organ culture substantially lengthens the time during which steady state conditions can be maintained in vitro , this approach as currently applied also has distinct limitations. First, current methodology does not permit investigators to distinguish secretion from the mucosal surface of cultured explants as opposed to secretion from the serosal surface. The second limitation is the fact that the technique is not practical for directly assessing the secretion of hydrochloric acid, a major function of oxyntic mucosa. Another difficulty is that, unlike standard cell culture techniques, the organ culture method does not permit addition of exogenous cells such as lymphocytes, which can then come into direct contact with the cultured explants.
CMS Reimbursement Reform

T o the Editor: In a well-designed study, Gidwani and Bhattacarya report that the incidence of venous thromboembolism (VTE) following elective hip and knee replacements decreased after Centers for Medicare and Medicaid Services (CMS) reimbursement reform. Although these results are encouraging at face value, an important alternate explanation was not addressed. Historically, routine screening for asymptomatic deep vein thrombosis after high-risk orthopedic procedures was advocated to prevent symptomatic VTE. In response to the disincentive of CMS reimbursement reform, institutions may have shifted their practice from liberal duplex ultrasonography testing of Medicare-aged patients to a more conservative approach of testing only symptomatic patients with a high likelihood of VTE. It would be informative to evaluate whether charges for duplex ultrasonography decreased in the post-reform cohort parallel with the incidence of VTE, suggesting a Byou can’t find what you don’t look for^ effect.
On the Integration of the Us Equity Markets

In response to the 1975 Congressional call for a national market system to provide a transparent link across individual markets that trade NYSE-listed stocks, the SEC caused the implementation of three electronic systems that provide a partial integration of these markets. This partial integration together with the trading process on the NYSE floor has created market niches in which non-NYSE markets can prosper. Empirically, the bid and asked prices of the NYSE quote are the primary determinant of the best displayed prices. Non-NYSE markets attract a significant portion of their volume for reasons other than matching or bettering the NYSE quote, such as "payment for order flow." This fragmentation of trading is a logical outgrowth of the SEC- imposed partial integration and the trading process on the NYSE floor.
Assessment of Potato Psyllid Bactericera cockerelli (Hemiptera: Triozidae) and Zebra Chip Disease in Four Commercial Potato Varieties in the Columbia Basin

Potato varieties may respond differently to the occurrence of arthropod pests including plant-pathogen. Although the potato psyllid, Bactericera cockerelli Sulc. (Hemiptera:Triozidae), the putative vector of Zebra Chip (ZC) disease, has been historically reported in the southern, central and western United States, the occurrence of the disease in the Pacific Northwest (PNW) is relatively new. Thus, there is a lack of information about infestation levels in commercial varieties, including russet potatoes, the predominant variety type of the region. In addition, susceptibility of russet varieties to ZC, which has become a serious production threat for the PNW since 2011, has not been thoroughly investigated. In the current 2-year study, the level of potato psyllid infestations and the impact of ZC disease in four commercial potato varieties, Ranger Russet, Russet Burbank, Umatilla Russet and Premier Russet, was evaluated. Psyllid adults were collected using a vacuum sampler based on an inverted leaf blower design, and leaf samples were used to collect eggs and nymphs. Also, ZC incidence and severity in fresh tubers was determined. The number of naturally occurring adults, nymphs and eggs per sample was similar among varieties suggesting a lack of affinity for any given variety. There was a positive relationship between the number of infective psyllids and disease incidence in 2011, while no relationship was detected in 2012. Although all varieties were equally susceptible to the disease, Ranger Russet numerically had the highest ZC incidence in tubers and Umatilla Russet the lowest.
Mass Organization and the Durability of Competitive Authoritarian Regimes: Evidence From Venezuela

Many studies highlight the critical roles of political parties in enhancing autocratic durability, mainly emphasizing mechanisms related to elite cohesion. The role of a mass party organization in stabilizing autocracies, though well recognized, has received relatively less emphasis. This article argues that the import of mass organization on autocratic durability is likely to vary with autocratic regime type and be greatest in competitive authoritarian regimes. I then exploit unusual survey data and an original data set containing information on 18,037 regime-affiliated “Communal Councils” to examine the effects of a regime-affiliated mass organization on the incumbent vote in Venezuela. The formation of Communal Councils exerted a large effect on incumbent support but the strength of this effect varied depending on whether Councils were located in communities receiving high levels of material resources. These findings suggest that mass organization can greatly enhance competitive authoritarian durabilit...
Early Axonal Area Measurement Predicts Early Nerve Regeneration Outcomes.

Background Study of peripheral nerve injury and regeneration in laboratory animals can be time consuming and expensive. This study determines if it is possible to reduce time and cost for a peripheral nerve regeneration study. Purpose The purpose of this study was to determine if nerve axonal area (NXA) or nerve fiber counting (NFC) correlates with compound muscle action potential (CMAP) recovery which is known to predict functional muscular recovery in the early stage of nerve regeneration. Methods In this study, six rats had a crush injury of the sciatic nerve without treatment. These rats were evaluated at 4 weeks of recovery with the following assessments: CMAP readings from the extensor digitorum longus, NXA measurement, and NFC. Results NXA correlated with CMAP; NFC did not correlate with CMAP. Conclusion NFC is not a reliable method for predicting muscular recovery in the early stages. NXA is a dependable assessment for muscular recovery in the early stages of nerve regeneration. Using NXA measurement can predict later electrophysiological and functional recovery. Using NXA with CMAP measurement for nerve injury, repair, and treatment in the animal study can save cost and time.
The type and linguistic foci of oral corrective feedback in the L2 classroom: A meta-analysis:

Research on corrective feedback (CF), a central focus of second language acquisition (SLA), has increasingly examined how teachers employ CF in second language classrooms. Lyster and Ranta’s (1997) seminal study identified six types of CF that teachers use in response to students’ errors (recast, explicit correction, elicitation, clarification request, metalinguistic cue, and repetition) as well as target linguistic foci (lexical, phonological, and grammatical errors). These taxonomies have remained dominant in observational studies conducted in a growing range of second language teaching contexts. Several studies have acknowledged that contextual factors may influence how teachers provide CF (e.g. Mori, 2002; Sheen, 2004) with few generalizable conclusions. The present study brings together research in this area in the first comprehensive synthesis of classroom CF research seeking to aggregate proportions of CF types teachers provide, as well as their target linguistic foci. Findings reveal that recasts ...
Length of Hospitalization After Joint Arthroplasty: Does Early Discharge Affect Complications and Readmission Rates?

Abstract Background Length of hospital stay is a quality metric in joint arthroplasty. Rapid recovery protocols have safely reduced the average length of hospitalization, but it is unclear whether there is a difference in complication and readmission rates between patients discharged the day of surgery or on postoperative day 1 (POD 1). We calculated 30-day complication and readmission after total knee arthroplasty (TKA), total hip arthroplasty (THA), and unicompartmental knee arthroplasty (UKA) based on day of discharge. We then analyzed the rapid recovery group by comparing those discharged the day of surgery and those discharged on POD 1. Methods Patients undergoing joint arthroplasty between 2011 and 2013 were selected from the American College of Surgeons (ACS) National Surgical Quality Improvement Program. Demographics, comorbidities, and 30-day complication and readmission were determined based on discharge date. Propensity-matched comparisons were performed between patients discharged POD 0 vs POD 1. We used multivariate logistic regression to determine independent risk factors for 30-day complication and readmission. Results There was no difference in complication or readmission after TKA or UKA between POD 0 or POD 1 discharge. In the propensity-matched cohort in THA, however, there was an increased rate of any complication in the POD 0 compared with the POD 1 discharge cohort. Risk factors for complication and readmission among THA, TKA, and UKA include age >80 years and smoking, and discharge after day 3. Conclusion Increased length of stay is associated with increased complication and readmission after joint arthroplasty for patients with a hospital stay of 3 or more days. However, in THA, there was an increased complication rate in patients discharged POD 0 as compared to POD 1. Efforts to improve patient selection are expected to reduce short-term complications after outpatient joint arthroplasty. Further research is needed to determine which patients can be discharged POD 0 without increased complication after THA.
Teaching critical thinking skills through commonly used resources in course-embedded online modules

ABSTRACTThe University of Louisville Quality Enhancement Plan focuses on integrating critical thinking into the undergraduate curriculum while using the Paul-Elder Critical Thinking Framework. In an effort to expand information literacy and outreach opportunities, the Social Sciences Librarian created online learning modules using SoftChalk, a program that enables the modules to be embedded into any Blackboard course shell. Originally created for an Introduction to Psychology course, the Critical Thinking & Information Evaluation Module Series maps information evaluation concepts to the Paul-Elder Framework's Elements of Thought through an examination of commonly used resources: Wikipedia, Google, and scholarly journal articles.
Utility of neurological smears for intrasurgical brain cancer diagnostics and tumour cell percentage by DESI-MS

Analysis of neurological smears by desorption electrospray ionization mass spectrometry (DESI-MS) is an emerging diagnostic strategy for intraoperative consultation in brain tumor resection. DESI-MS allows rapid sampling while providing accurate diagnostic information. We assess the chemical homogeneity of neurological smears using DESI-MS imaging and the quality of rapid DESI-MS diagnosis.
51-P : C4d STAINING AND HISTOLOGICAL FEATURES OF PROTOCOL LUNG BIOPSIES IN PATIENTS WHO DEVELOP DE NOVO DONOR HLA SPECIFIC ANTIBODIES

Aim In this study we aimed to compare the frequency of histological findings commonly evaluated in transplant lung biopsies and immunofluorescent staining for C4d among transplant recipients with de novo donor HLA specific antibodies (dDSA). Methods We retrospectively analyzed the records of 103 lung transplant biopsies obtained from 36 recipients transplanted at our institute in 2011-2012 and were on routine post-transplant monitoring for dDSA within ±1 week of the a biopsy date (paired biopsies). dDSA testing was performed using Luminex single antigen beads (Thermo Fisher Scientific, Canoga Park, CA). All recipients had protocol bronchial biopsies at 2 weeks, 1, 3, 6, 12 months and for cause thereafter. Results Eighteen biopsies were obtained from patients with only class I dDSA, 47 from patients with only class II dDSAand 38 from those with both class I and class II dDSA. Interestingly, of the 47 biopsies with class II dDSA 35 presented with DQ and 30 of them had DQ dDSA only. We compared dDSA status with the following histological findings: C4d staining, acute rejection ⩾ISHLT grade 2A & B, and acute lung injury (ALI/OALI with/out PMNs). The distribution of histological findings in biopsies in association with dDSA characteristics in terms of class I versus class II is shown in the following: [ Table 1 ] Conclusions dDSA to DQ seems to be disproportionately more frequent than dDSA to other loci and was the only dDSA detected in the majority of patients with class II dDSA only. However, in this cohort, there was no evidence of an association between any of the evaluated biopsy findings and dDSA characteristics in terms of class I versus class II dDSA.
Scintillation sensing of 18 F-FDG for the detection of metabolically active atherosclerotic plaque

Atherosclerosis and its consequences are the main cause of mortality in the United States and the western world. Detection of metabolically active regions of atherosclerotic plaque can provide insights on those plaques that are prone to rupture, leading to a tissue infarction. The metabolic activity of these plaques can be identified using positron emission tomography (PET). However, such detection has been elusive in the coronary arteries due to motion and detection sensitivity. One of the techniques capable of improving precision as an affordable alternative is the use of an optical scintillating fiber for the detection of 18-Fluorine Fluorodeoxyglucose (18F-FDG), a compound that is accumulated in metabolically active areas of the atherosclerotic plaque. Here we report on a prototype scintillating fiber detection system designed to characterize the beta emission, particularly positron emission, by 18F-FDG. We demonstrate the ability to effectively measure the presence of 18F-FDG contained in-vivo along with the ability discriminate against ambient light based on energy. This paper presents a catheter-based hardware and software platform based on the use of a scintillating fiber optic catheter. The system measures a short (2–3 ns) burst of photons that are generated by the stimulation of the plastic scintillating fiber by a positron (633 kEv) emitted by the radioactive compound. It can be used to determine the presence of 18F-FDG in-vivo and accurately detect the active decay as the 18F-FDG retained in the metabolically active plaque. The proposed instrument was tested in-vitro and its sensitivity was also measured in-vivo. The developed system may be used in the detection of 18F-FDG, as surrogate of inflammation, providing critical in-vivo information of the metabolism in areas of inflammation.
Public Drinking Water in the United States

The provision of safe and reliable drinking water to most of the U.S. population is ranked as one of the 10 major public health achievements of the twentieth century (CDC, 1999). Over 250 million Americans, who are about 90% of the estimated population, currently are served by about 54,000 public water systems. In those systems, over 80 contaminants are regulated and hundreds of water quality parameters are monitored. Total expenditures for public drinking water in the U.S. are about $36 billion per year.
Segmentation and mobility of women in Argentine labor markets

Este trabajo analiza la movilidad laboral de las mujeres en la Argentina en 1995-2003 en 4 sectores: formal, informal, desempleo e inactividad. Incorporamos medidas alternativas de movilidad laboral, y estimamos un modelo logistico multinomial para la eleccion del sector. Los resultados son consistentes con la hipotesis de mercados laborales segmentados. Mujeres con estudios superiores, incluso casadas y con hijos, acceden mas facilmente al sector formal que mujeres menos educadas. No madres experimentan menos obstaculos para moverse del sector informal al formal. Tener mas hijos aumenta la probabilidad de transicion del sector formal al informal y del informal a salir del mercado de trabajo
Potential Allergenicity of Novel Proteins in Murine Models

Bioengineered crops represent an important advancement for farmers who want to avoid losses caused by insect infestations or adverse environmental conditions. However, the use of modern biotechnology has raiised questions regarding the safety of bioengineered foods because of the potential allergenicity of proteins expressed by the newly introduced genes. Standard approaches for safety assessment of these foods are still evolving. Animal models have been suggested as a tool that could help evaluate the potential allergenicity of such compounds. Several investigators are developing animal models to evaluate novel proteins, but none of these have yet been validated. This article reviews the published murine models, rat and mouse in particular, and the different methods used to evaluate parameters related to allergy. It also addresses the factors involved in the development of a model. Finally, it raises some questions that should be considered by the international community so that financial and intellectual efforts can be addressed in a unified manner.
A Physiological Basis for Pharmacological Activities of Copper Complexes: An Hypothesis

Copper is recognized as an essential metalloelement like sodium, potassium, magnesium, calcium, iron, zinc, chromium, vanadium, and manganese1. Like essential amino acids, essential fatty acids, and essential cofactors (vitamins), essential metalloelements are required for normal metabolic processes but can not be synthesized in vivo and daily dietary intake and absorption are required. The adult body contains between 1.4 and 2.1 mg of copper per kilogram of body weight. The infant body contains 3 times this amount which is consistent with the fact that their metabolic needs are that much greater than adults. All tissues of the body need copper for normal metabolism but some tissues have greater metabolic needs than others and tissue contents of copper reflect this fact. Amounts of copper found in various body tissues and fluids of individuals are shown in Table I2,3.
Dracula Conditionals and Discourse

What I wish to suggest in this study is this: an adequate theory of meaning for language can only be based on the understanding that we, the speakers of language, are FEELING entities as well as THINKING entities.1 As a case study, I will examine colloquial English expressions such as (1), henceforth ‘Dracula conditionals’ (and abbreviated as ‘DC’).
Anisotropy Level Prediction Model for Unbound Aggregate Systems

Several researchers have studied anisotropy or directional dependency of material properties of aggregate systems (Tutumluer, et al. 1997), (Adu-Osei et al. 2001), (Kim et al. 2005). Tutumluer suggested the use of anisotropic constitutive models to characterize the response of aggregate base layers in flexible pavements (Tutumluer et al. 1997). He reported that the use of a cross-anisotropic model results in a drastic reduction or in some cases elimination of tensile stresses at the bottom of an unbound layer that are generally calculated using isotropic layered elastic solutions. He also found that compressive stresses throughout the aggregate layer and at the top of the subgrade are generally higher when the aggregate layer is considered as nonlinear and anisotropic. This conforms to results reported by Adu-Osei and Kim.
Assessing the impact of wastewater treatment plant effluent on downstream drinking water-source quality using a zebrafish (Danio Rerio) liver cell-based metabolomics approach.

Cell-based metabolomics was used in a proof-of-concept fashion to investigate the biological effects of contaminants as they traveled from a wastewater treatment plant (WWTP) discharge to a drinking water treatment plant (DWTP) intake in a surface-water usage cycle. Zebrafish liver (ZFL) cells were exposed to water samples collected along a surface-water flowpath, where a WWTP was located ∼14.5 km upstream of a DWTP. The sampling sites included: 1) upstream of the WWTP, 2) the WWTP effluent discharging point, 3) a proximal location downstream of the WWTP outfall, 4) a distal location downstream of the WWTP outfall, 5) the drinking water intake, and 6) the treated drinking water collected prior to discharge to the distribution system. After a 48-h laboratory exposure, the hydrophilic and lipophilic metabolites in ZFL cell extracts were analyzed by proton nuclear magnetic resonance (1H NMR) spectroscopy and gas chromatography-mass spectrometry (GC-MS), respectively. Multivariate statistical analysis revealed distinct changes in metabolite profiles in response to WWTP effluent exposure. These effects on the hydrophilic metabolome gradually diminished downstream of the WWTP, becoming non-significant at the drinking water intake (comparable to upstream of the WWTP, p = 0.98). However, effects on the lipophilic metabolome increased significantly as the river flowed from the distal location downstream of the WWTP to the drinking water intake (p < 0.001), suggesting a source of bioactive compounds in this watershed other than the WWTP. ZFL cells exposed to treated drinking water did not exhibit significant changes in either the hydrophilic (p = 0.15) or lipophilic metabolome (p = 0.83) compared to the upstream site, suggesting that constituents in the WWTP effluent were efficiently removed by the drinking water treatment process. Impacts on ZFL cells from the WWTP effluent included disrupted energy metabolism, a global decrease in amino acids, and altered lipid metabolism pathways. Overall, this study demonstrated the utility of cell-based metabolomics as an effective tool for assessing the biological effects of complex pollutant mixtures, particularly when used as a complement to conventional chemical monitoring.
Percutaneous Release of the Finger Joints and Mini-Open Intrinsic Release With Tenolysis: A Cadaveric Study.

Purpose To evaluate the effectiveness and safety of minimally invasive distal intrinsic release and extensor tenolysis combined with percutaneous release of proximal and distal interphalangeal joint collateral ligaments . Methods The procedures were performed on 5 cadaveric upper extremity specimens, followed by a full anatomical dissection to assess completeness of the targeted releases and any damage to surrounding structures. Results Complete distal intrinsic release, dorsal capsule release, and distal interphalangeal collateral ligament release was performed on all specimens. We achieved complete release of all proximal interphalangeal joint collateral ligaments in 38 of 40 specimens (95%). We noted damage to nontargeted structures in 2 instances (5%). Conclusions Minimally invasive and percutaneous techniques can effectively release several structures known to cause finger stiffness with minimal damage to surrounding structures. Clinical relevance If similar results are seen in clinical trials, this could be a quick and easy way to increase the mobility of a stiff finger with potentially minimal morbidity.
You’re My Pin-up Girl!: The Politics of Jazz Fandom and the Making of Mary Lou Williams in the 1940s

Yamada delves into the relationship between African American woman jazz pianist Mary Lou Williams and her fans in the mid-1940s. While acknowledging fans’ engagement in promoting the pianist as a sign of rising consumerism in the postwar period, his study suggests that the crux of fan activities lies in an attempt to imagine and form a novel way of sociality at a time when the United States was undergoing reconfigurations of race and gender relations. Making use of fan mail and a fan magazine, the chapter also discusses Williams’s struggle with the dual expectations of artistry and glamour and argues that highlighting the voices of fans presents a more complicated view of an African American artist and the sociocultural context that surrounded her.
Polyphasic Rhabdomyositis in California Sea Lions (Zalophus Californianus): Pathology and Potential Causes:

A myositis syndrome has been recognized for more than a decade in California sea lions (CSLs; Zalophus californianus) but a detailed description of the lesions and potential causes of this condition is lacking. The tissues of 136 stranded CSLs with rhabdomyositis were examined. Rhabdomyositis was considered incidental in 67% (91/136) of the CSLs, and a factor contributing to the animal stranding (significant rhabdomyositis) in 33% (45/136). Of the 91 cases with incidental rhabdomyositis, lesions consisted of a few small foci of lymphohistiocytic inflammation. Of the 45 cases with significant rhabdomyositis, 28 (62%) also presented with major comorbidities such as leptospirosis (2 animals) and domoic acid toxicosis (6 animals), whereas 17 (38%) had severe polyphasic rhabdomyositis as the only major disease process associated with mortality. In these animals, most striated muscles had multiple white streaks and diffuse atrophy. Microscopically, there was myofiber necrosis surrounded by lymphocytes and histiocytes admixed with areas of myofiber regeneration, and/or moderate to severe rhabdomyocyte atrophy usually adjacent to intact Sarcocystis neurona cysts. At the interface of affected and normal muscle, occasional T lymphocytes infiltrated the sarcoplasm of intact myocytes, and occasional myofibers expressed MHCII proteins in the sarcoplasm. S. neurona antibody titers and cyst burden were higher in animals with significant polymyositis antibody titers of (26125 ± 2164, 4.5 ± 1.2 cysts per section) and active myonecrosis than animals with incidental rhabdomyositis antibody titers of (7612 ± 1042, 1.7 ± 0.82 cysts per section). The presented findings suggest that S. neurona infection and immune-mediated mechanisms could be associated with significant polyphasic rhabdomyositis in CSLs.
Temporal dynamics of nitrogen cycle gene diversity in a hyporheic microbiome

Biodiversity is thought to prevent decline in community function in response to changing environmental conditions through replacement of organisms with similar functional capacity but different optimal growth characteristics. We examined how this concept translates to the within-gene level by exploring seasonal dynamics of within-gene diversity for genes involved in nitrogen cycling in hyporheic zone communities. Nitrification genes displayed low richness - defined as the number of unique within-gene phylotypes - across seasons. Conversely, denitrification genes varied in both richness and the degree to which phylotypes were recruited or lost. These results demonstrate that there is not a universal mechanism for maintaining community functional potential for nitrogen cycling activities, even across seasonal environmental shifts to which communities would be expected to be well adapted. As such, extreme environmental changes could have very different effects on the stability of the different nitrogen cycle activities. These outcomes suggest a need to modify existing conceptual models that link biodiversity to microbiome function to incorporate within-gene diversity. Specifically, we suggest an expanded conceptualization that (1) recognizes component steps (genes) with low diversity as potential bottlenecks influencing pathway-level function, and (2) includes variation in both the number of entities (e.g. species, phylotypes) that can contribute to a given process and the turnover of those entities in response to shifting conditions. Building these concepts into process-based ecosystem models represents an exciting opportunity to connect within-gene-scale ecological dynamics to ecosystem-scale services.
From Biafra to police brutality: challenging localized Blackness toward globally racialized ethnicities of Nigerians in the U.S.

This article reveals how Nigerians in the U.S. negotiate their multiple forms of Black racialization. They incorporate both local and global social scripts within their intersected subjectivities a...
Mother tongue activism and language shift in multilingual India: Marathi in Pune, Maharashtra

This article outlines the extracurricular work of education and language revitalization by two non-governmental organizations (NGOs) in Pune, a city in the western Indian state of Maharashtra. It d...
Elevating your breast program to the next level

This paper describes a series of steps taken to elevate the Hoag Breast Program to the next level. The hope is that some of our ideas will be useful to you and your breast program.
Transients on arc and Convertor Currents in the Multi-Cusp Cesiated Surface Conversion H-Ion Source at Lansce

The Multi-cusp Cesiated Surface Conversion H- Ion Source at the Los Alamos Neutron Science Center (LANSCE) has provided beam at ~14 mA, 120 Hz, and 10% D.F. for many years of neutron science research. Recently, random high current transients were discovered in the arc current used to ionize hydrogen in the LANSCE H- ion source, and in the convertor current used to convert protons to H- ions. Most have no effect, but more severe transients can cripple beam output. Hypothesized causes are related to cesiation effects, plasma instabilities, tungsten filament evaporation/sputtering, or from the arc modulator circuitry. A dedicated study was recently done on the LANSCE H- Ion source test stand to determine the cause of these transients. Current understanding indicates that the more severe transients come from a combination of cesiation effects and plasma instabilities. The status of these current transient studies on the LANSCE H- ion source will be discussed.
Can fund sentiment beta predict future performance

Using both actual and bootstrapped fund samples, this paper examines whether fund sentiment beta (FSB) can be used to predict future fund performance, whether FSB exhibits persistence across time periods, and whether FSB affects fund selectivity. We find that FSB has no significant effect on either current or subsequent fund performance and that it does not exhibit any persistence across time. Also, we find no evidence of a relationship between FSB and fund selectivity. Contrary to prior research, these findings suggest that an FSB-based strategy is unlikely to be a profitable strategy for fund managers.
Concept of Drug Delivery

The past two decades have hosted a revolution in material science. In many cases it is now possible to manipulate atoms, and molecules within materials one at a time, and therefore, to construct materials with nano-scale (i.e. the size of individual molecules) precision. The potential intersection between nanotechnology and biological sciences is vast. The drug delivery technology landscape is representative field, highly competitive and rapidly evolving. The market involves both numerous startups and major players in the medical device, pharmaceutical and biotechnology industries. This is a market with intensive intellectual property protection. Products that have been brought to market or that are in clinical trials often involve combinations of technologies from multiple players, with complex licensing and strategic partnering relationships. Drug delivery could be thought of an integration of biomaterials, nanotechnology and targeted system evolution, meaning that essential goal is recognition of the targeted tissue.
Detecting Articular Cartilage and Meniscus Deformation Effects Using Magnetization Transfer Ultrashort Echo Time (MT-UTE) Modeling during Mechanical Load Application: Ex Vivo Feasibility Study.

ObjectiveUltrashort echo time (UTE) magnetic resonance imaging (MRI) sequences have improved imaging of short T2 musculoskeletal (MSK) tissues. UTE-MRI combined with magnetization transfer modeling...
Internal Multiple Removal and Illumination Correction for Seismic Imaging

Marchenko equation-based imaging methods have been proved as an effective way to remove the internal multiples. Conventional Marchenko imaging needs the reflection response at the surface and an estimate of the direct arrival times from the virtual source point to the acquisition surface. It contains the procedure of redatuming and imaging. The redatuming process is valid only for layered media with a moderately curved interface. We rederive the single reflection retrieval by a focusing source method based on the scattering theory and avoid the use of redatuming plane and the upgoing/downgoing decomposition. This scheme reproduces a new data free from internal multiples for complex structures, such as salt dome. Our theory/method expands the application range of Marchenko imaging and internal multiple elimination. With an artifact-free image obtained by this procedure, an illumination compensation can be further applied to obtain a high-fidelity image, especially in the subsalt area. Numerical examples using the 2-D SEG/EAGE salt model are shown to validate this method.
To tweet or not to tweet: Examining CEO impression management on Twitter

CEOs engage in impression management to influence the perceptions of themselves and the firms they lead. The focus of past research on CEO impression management has been on the messages initiated b...
AI and the Future of Education

It has become clear that AI will profoundly transform society. AI will dramatically change the socio-technological landscape, produce seismic economic shifts, and fundamentally reshape the workforce in ways that we are only beginning to grasp. With its imminent arrival, it is critically important to deeply engage with questions around how we should design education in the Age of AI. Fortunately, while we must address the significant challenges posed by AI, we can also leverage AI itself to address these challenges. In this talk we will consider how (and at what rate) AI technologies for education will evolve, discuss emerging innovations in AI-augmented learning environments for formal and informal contexts, and explore what competencies will be elevated in an AI-pervasive workforce. We will discuss near-future AI technologies that leverage advances in natural language processing, computer vision, and machine learning to create narrative-centered learning environments, embodied conversational agents for learning, and multimodal learning analytics. We will conclude by considering what all of these developments suggest for K-12 education and the future of human learning.
Concurrency and Interference

We now add statements for concurrency and synchronization to the sequential programming notation of Chapter 4. We also extend Proof Outline Logic, using interference freedom to characterize when a valid proof outline for a concurrent program can be derived from valid proof outlines for its component processes. Synchronization statements are then viewed as mechanisms to prevent interference.
Las comadres y conavigua. Mujeres centroamericanas buscando un espacio para sus reivindicaciones

Contra lo que es usual en los analisis sobre los movimientos de mujeres en America Latina, este articulo enmarca teoricamente el surgimiento y desarrollo de los casos especificos que estudia. Asimismo, se abunda sobre el contexto social y politico en que se desarrollan ambas experiencias, lo cual permite reconocer las similitudes, pero tambien las diferencias que existen entre estos dos movimientos tan cercanos geografica y temporalmente. Uno de los aspectos mas interesantes que se desarrollan es la constatacion de que en el caso de las mujeres centroamericanas, debido a su condicion social, no es aplicable el modelo teorico que separa el espacio publico del privado.
SPL1-1, a Saccharomyces cerevisiae mutation affecting tRNA splicing.

Abstract A genetic approach was used to isolate and characterize Saccharomyces cerevisiae genes affecting tRNA processing. Three mutants were isolated which were able to process and utilize splicing-deficient transcripts from inactivated Schizosaccharomyces pombe suppressor tRNA genes. Extragenic recovery of suppressibility was verified by the suppression of nonsense mutations in LEU2, HIS4, and ADE1. One mutant, SPL1-1, was chosen for detailed analysis on the basis of its increased synthesis of mature suppressor tRNA over wild-type cell levels as determined by Northern (RNA) analysis. This mutant exhibited strong suppression exclusively with the defective tRNA gene used in the mutant selection. Genetic analysis revealed that a single, dominant, haplo-lethal mutation was responsible for the suppression phenotype. The mutation mapped on chromosome III to an essential 1.5-kb open reading frame (L. S. Symington and T. D. Petes, Mol. Cell. Biol. 8:595-604, 1988), recently named NFS1 (S. G. Oliver et al., Nature [London] 357:38-46, 1992), located adjacent (centromere proximal) to LEU2.
Two Examples of Applied Universal Algebra

In the long run, mathematics evolves organically and is independent of individual mathematicians. Multiple, and in many cases, almost simultaneous discovery of concepts or proofs of theorems is the norm rather than the exception. Someone will discover the concept or prove the theorem, eventually. Gian-Carlo Rota often praised an idea, detached from its accidental discoverers, as “an idea whose time has come”. In the 1960s, the time came for the theory of Mobius functions of partially ordered sets, and the area has flourished since then. Rota did not include his paper Foundations I [4] among his most original papers. In his opinion, he only uncovered a theory already “ there”.
Abstract 3642: Cancer therapy by resuscitating Notch immune surveillance

The immunosuppressive tumor microenvironment perturbs numerous immune regulatory networks and usurps host anti-tumor immunity. We discovered that tumor interferes with host hematopoietic Notch system in lung cancer patients. The resultant decrease in immune Notch signaling could be a major causative link in the inadequate induction of anti-tumor immunity. Interestingly, we found that tumor-induced decrease in immune Notch in various mouse solid tumor models could be restored therapeutically by the following two agents. Administration of a novel Delta-like ligand 1 (DLL1) multivalent cluster and the FDA-approved proteasome inhibitor drug bortezomib - which also sensitizes tumors to death signals - could activate Notch 1 signaling in lymphoid cells of tumor-bearing mice without increasing tumor cell proliferation or clonogenicity. Systemic activation of DLL1-Notch signaling could attenuate tumor vascularization as well as increase T cell infiltration in tumor, decrease proportion of regulatory T cells and enhance antitumor T cell function and memory in multiple mouse tumor models. New data also show that bortezomib affects the expression of notch receptors and ligands differentially in lymphocytes and in a wide range of solid tumor cells. Moreover, bortezomib administration increased the expression of Notch target genes Hes 1 and Hey 1 in thymus, lymph node, and spleen, as well as decreased the proportion of regulatory T cells and enhanced T cell production of IFN-γ in tumor-bearing mice. Results indicate that bortezomib-induced activation of Notch target genes Hes 1 and Hey 1 is through its inhibition of NFkB while its activation of another Notch target gene Deltex 1 is mediated via PI3K. The findings suggest a potential synergistic action of bortezomib and DLL1 activation of Notch signaling. The potential of modulating anti-tumor Notch signaling by the prototypic DLL1 cluster in combination with bortezomib presents exciting opportunities to uncover multi-pronged immune stimulatory regimens. Therapeutic restoration of immune Notch signaling could provide effective treatment and recurrence-free survival in cancer patients by breaking tumor resistance, enhancing immune surveillance, and sustaining robust anti-tumor immunity. Citation Format: Duafalia F. Dudimah, Samuel T. Pellom Jr., Roman V. Uzhachenko, David P. Carbone, Mikhail M. Dikov, Anil Shanker. Cancer therapy by resuscitating Notch immune surveillance. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 3642. doi:10.1158/1538-7445.AM2014-3642
HMG PROTEINS 1 AND 2 ARE REQUIRED FOR TRANSCRIPTION

Publisher Summary This chapter describes a study in which chromatin active in transcription was prepared from isolated nuclei. Treatment of the chromatin with 0.35 M KCl in the presence of 5 m Mg++ greatly reduced transcription. Transcription could be restored by adding back the extracted material. The major proteins extracted from chromatin by this procedure were HMG 1 and 2. They were purified by differential precipitation with trichloroacetic acid and gel filtration. The addition of pure HMG proteins 1 and 2 to chromatin depleted of HMG 1 and 2 enhanced transcription from 3 fold to 5 fold. The production of specific RNA polymerase III transcripts, 5S rRNA, and the 4.5S tRNA precursors was measured by gel electrophoresis. The addition of HMG proteins 1 and 2 stimulated transcription in a concentration-dependent manner with maximum stimulation when the amounts of HMG 1 and 2 added back were equal to the amounts extracted. Addition of HMG 14 and 17 had no effect on transcription. The results suggested that HMG proteins 1 and 2 are associated with regions of chromatin being transcribed, and their presence is required for the transcription to occur.