cssi/SciSciGPT-SciSciNet huggingface dataset:
Purification and Properties of a Unique Nucleotide Pyrophosphatase/Phosphodiesterase I That Accumulates in Soybean Leaves in Response to Fruit Removal

Several unique proteins accumulate in soybean (Glycine max) leaves when the developing fruits are removed. In the present study, elevated levels of nucleotide pyrophosphatase and phosphodiesterase I activities were present in leaves of defruited soybean plants. The soluble enzyme catalyzing these reactions was purified nearly 1000-fold, producing a preparation that contained a single 72-kD polypeptide. The molecular mass of the holoenzyme was approximately 560 kD, indicating that the native enzyme was likely octameric. The purified enzyme hydrolyzed nucleotide-sugars, nucleotide di- and triphosphates, thymidine monophosphate p-nitrophenol, and inorganic pyrophosphate but not nucleotide monophosphates, sugar mono- and bisphosphates, or NADH. The subunit and holoenzyme molecular masses and the preference for substrates distinguish the soybean leaf nucleotide pyrophosphatase/phosphodiesterase I from other plant nucleotide pyrophosphatase/phosphodiesterase I enzymes. Also, the N-terminal sequence of the soybean leaf enzyme exhibited no similarity to the mammalian nucleotide pyrophosphatase/phosphodiesterase I, soybean vegetative storage proteins, or other entries in the data bank. Thus, the soybean leaf nucleotide pyrophosphatase/phosphodiesterase I appears to be a heretofore undescribed protein that is physically and enzymatically distinct from nucleotide pyrophosphatase/phosphodiesterase I from other sources, as well as from other phosphohydrolytic enzymes that accumulate in soybean leaves in response to fruit removal.
Tables of single-particle reduced matrix elementsof spherical tensors

All allowed reduced matrix elements of the spherical tensor operators TLSJ, M(θ, ; σ) and TJ−1,1J,M(θ, ; L) have been computed between all pairs of single-particle states from s1/2 to j15/2.
Despair and the determinate negation of Brandom’s Hegel

In this paper, I contend that Brandom’s interpretive oversights leave his inferentialist program vulnerable to Hegelian critique. My target is Brandom’s notion of “conceptual realism,” or the thesis that the structure of mind-independent reality mimics the structure of thought. I show, first, that the conceptual realism at the heart of Brandom’s empiricism finds root in his interpretation of Hegel. I then argue that conceptual realism is incompatible with Hegel’s thought, since the Jena Phenomenology, understood as a “way of despair,” includes a critique of the philosophical framework upon which conceptual realism relies. Finally, I offer the Hegelian critique of Brandom that results from these textual infidelities.
Saturation spectroscopy in molecular iodine by intermodulated fluorescence

Abstract The hyperfine structures of the P(13)R(15) (43−0) lines (5145A) in molecular iodine were observed at very low pressures using a new saturated fluorescence technique. Two oppositely-directed beams from the same laser are chopped at different frequencies and the modulation of the fluorescence is monitored at the sum frequency.
Discrimination of GLUT4 vesicle trafficking from fusion using a temperature-sensitive Munc18c mutant.

To examine the temporal relationship between pre- and post-docking events, we generated a Munc18c temperature-sensitive mutant (Munc18c/TS) by substitution of arginine 240 with a lysine residue. At the permissive temperature (23°C), overexpression of both the wild type (Munc18c/WT) and the R240K mutant inhibited insulin-stimulated GLUT4/IRAP vesicle translocation. However, at the non-permissive temperature (37°C) only Munc18c/WT inhibited GLUT4/IRAP translocation whereas Munc18c/TS was without effect. Moreover, Munc18c/WT bound to syntaxin 4 at both 23 and 37°C whereas Munc18c/TS bound syntaxin 4 only at 23°C. This was due to a temperature-dependent conformational change in Munc18c/TS, as its ability to bind syntaxin 4 and effects on GLUT4 translocation were rapidly reversible while protein expression levels remained unchanged. Furthermore, insulin stimulation of Munc18c/TS-expressing cells at 23°C followed by temperature shift to 37°C resulted in an increased rate of GLUT4 translocation compared with cells stimulated at 37°C. To date, this is the first demonstration that the rate-limiting step for insulin-stimulated GLUT4 translocation is the trafficking of GLUT4 vesicles and not their fusion with the plasma membrane.
Capacity planning for toll roadways incorporating consumer wait time costs

This paper reports the findings for an investigation concerning capacity planning analysis for toll-plaza operations. The study develops a cost minimizing capacity planning model that minimizes expected costs which include both operating and user costs. A reliability constraint is appended to the formulation to account for the service provider's sensitivity to demand for quality. Optimal capacity levels are determined for both peak and off-peak hours. Subsequently, a work force policy is obtained through the utilization of a mathematical program. The research suggests that significant savings may accrue through the implementation of a decision support system which may be developed from the models presented.
Income redistribution: An international perspective

Many view global income inequality as a problem. Income redistribution from the rich countries to poor countries is often offered as a solution. However, such redistribution would have to be politically acceptable to voters in rich countries to occur. Using a constructed distribution of world income we show that even modest income redistribution efforts would impose significant costs on taxpayer-voters in rich countries. We conclude such income redistribution is unlikely.
Human papillomavirus‐related high‐grade squamous intraepithelial lesions of the esophagus, skin, and cervix in an adolescent lung transplant recipient: a case report and literature review

High-risk (carcinogenic) genotype human papillomavirus (HPV) infections can be associated with significant morbidity in the immunocompromised solid organ transplant (SOT) recipient. Immunosuppression-associated persistent infection can predispose to the development of rapidly progressive high-grade squamous intraepithelial lesions (HSIL) in this population. We present a case report of an adolescent bilateral lung transplant recipient who developed HSIL of the esophagus, cervix, and skin secondary to HPV. This review highlights the unique developmental needs of the sexually active adolescent SOT recipient and reviews guidelines for HPV-related screening and education of this population.
Molecular Precursors for Ferroelectric Materials: Synthesis and Characterization of Bi2M2(μ-O)(sal)4(Hsal)4(OEt)2 and BiM4(μ-O)4(sal)4(Hsal)3(OiPr)4 (sal = O2CC6H4O, Hsal = O2CC6H4OH) (M = Nb, Ta)

Reactions between triphenyl bismuth, salicylic acid, and niobium or tantalum ethoxide have been explored. Four new coordination complexes incorporating bismuth and the group 5 metals niobium or tantalum have been synthesized and characterized spectroscopically, by elemental analysis, and by single crystal X-ray diffraction. The new complexes are Bi2M2(μ-O)(sal)4(Hsal)4(OEt)2 (1a, M = Nb; 1b, M = Ta) and BiM4(μ-O)4(sal)4(Hsal)3(OiPr)4 (sal = O2CC6H4-2-O, Hsal = O2CC6H4-2-OH) (2a, M = Nb; 2b, M = Ta). Complexes 1a and 1b are isomorphous, as are 2a and 2b. The thermal and hydrolytic decomposition of 1a has been explored by DT/TGA and powder X-ray diffraction, while scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) were used to characterize the morphology and composition of the oxides. The heterobimetallic molecules are completely converted to the amorphous bimetallic oxide by heating to 500 °C in air. Decomposition of 1a or 1b at 650 °C produces the metastable high temperature...
African-American Teenagers’ Stories of Attention Deficit/Hyperactivity Disorder

Cultural differences in illness perceptions and treatment access of teens with attention deficit/hyperactivity disorder (ADHD) are evident yet under studied. The purpose of this qualitative paper is to explore how African-American teenagers describe and narrate stories about their lives with ADHD. Data were gathered from four African-American teens in the Southern United States through a qualitative experience sampling method, and stories were analyzed using narrative analysis framed within the context of African-American rhetorical traditions. We argue that the study of teen-constructed narratives and culturally-situated talk are tools that can improve communication between healthcare providers and teens by illuminating the ways teens construct their personalized realities of ADHD.
9. Multi-dimensional assessment of pancreatic cancer cell responses to cryoablation in vitro

As the incidence of pancreatic cancer (PaCa) continues to increase worldwide with little improvement in the overall prognosis, there is a drive to identify alternative strategies for the treatment of PaCa to prolong patient survival. To this end, several reports have described the potential benefits of the use of cryoablation for the treatment of PaCa. While promising, few studies have been reported examining the physical and molecular response of PaCa to cryoablation. An understanding of these responses is critical to serve as supportive and guidance information if the use of cryo for the treatment of PaCa is to continue to grow. In an effort to detail the effects of freezing in pancreatic cancer (PaCa), a human PaCa cell line (Bx-PC3) was evaluated in vitro and using an in vivo -like tissue engineered model ( PaCaTEM ). Bx-PC3 were exposed to a range of freezing temperatures from −10 °C to −20 °C and compared to non-frozen controls. PaCaTEM models were frozen in situ following a single 5 min freeze protocol using the supercritical nitrogen (SCN) cryoablation system with a 1.5 mm × 3 cm cryoprobe. Following freezing, cell survival was assessed in the in vitro studies using the metabolic activity indicator, alamarBlue and microfludic flow cytometry (MFC). Assessment of PaCaTEM samples included monitoring of iceball size and isothermal distribution during the freezing process as well as assessment of cell ablation at 1 and 24 h post-freeze via fluorescence microscopy (Vybrant apoptosis assay). Results from in vitro experiments showed that freezing to −10 °C did not affect Bx-PC3 viability, while −15 °C and −20 °C resulted in a significant loss of viability (90% and 98%, respectively). A complete loss of cell viability was evident at temperatures of −25 °C and colder in vitro . Temporal analysis of the cell response to freezing via MFC revealed that following exposure, there was an initiation of both apoptotic and necrotic responses. Specifically, following freezing to −15 °C, apoptotic cell death was found to peak at 4hrs and necrosis at 8hrs post-thaw. Analysis of the PaCaTEM samples revealed the creation of a 3.0 cm (±0.2 cm) diameter iceball with extension of the −25 °C isotherm to a diameter of 2.0 cm (±0.1 cm). Fluorescence imaging of the PaCaTEM revealed complete PaCa cell ablation to a diameter of 1.9 cm (±0.2 cm) with a transitional zone of cell death extending to the margin of the iceball. This zone of ablation correlated to complete cell destruction below 25 °C in in vivo -like tissue. The results of this study show that cryoablation is an effective tool for the targeted ablation of pancreatic cancer. Further, the data suggest that a temperature of −25 °C may serve as a target temperature to be reached at the margin of a tumor to assure complete PaCa destruction.
SENSORY AND SELECTED TEXTURAL PROPERTIES OF PASTA FORTIFIED WITH PLANT PROTEINS AND WHEY

Sensory and mechanical properties evaluation were run on pasta products fortified with eight different high protein sources. Some mechanical and compositional properties were analyzed for the expressed purpose of using them as predictors of texture as evaluated by a trained sensory panel. The combination of the rupture force and a creep recovery factor proved to be a relatively good predictor of the textural quality of the cooked products. An analysis of variance indicated that in order to obtain an acceptable protein fortified pasta product, attention should be given to the source of protein. The level of substitution of fortification was found to be of little significance as far as texture is concerned.
Autoerotic deaths – practical forensic and investigative perspectives

This remarkable book combines the expertise of the medical profession with that of law enforcement, resulting in a text that is the most up to date and complete analysis of autoerotic deaths. Anny ...
Introduction to Fourier Transform Spectroscopy

This paper provides an introduction to Fourier transform spectroscopy. The basic concepts of the Fourier transform technique are reviewed. These include the characteristics and generation of interferograms and the generation of spectra by the Fourier transformation of interferograms. The multiplex and throughput advantages and the data handling disadvantages are also discussed. The optical, electronic, and data-handling instrumentation and techniques necessary for a Fourier transform spectrometer system are, in general, quite different from those of a conventional prism or grating spectrometer. The requirements of these areas are outlined and recent developments are reviewed. The Fourier transform technique has been successfully applied to a number of spectral measurements from the visible through to the far infrared. Some of the more recent applications are discussed.
Depressive Symptoms Are Associated with Mental Stress-Induced Myocardial Ischemia after Acute Myocardial Infarction

Objectives Depression is an adverse prognostic factor after an acute myocardial infarction (MI), and an increased propensity toward emotionally-driven myocardial ischemia may play a role. We aimed to examine the association between depressive symptoms and mental stress-induced myocardial ischemia in young survivors of an MI. Methods We studied 98 patients (49 women and 49 men) age 38–60 years who were hospitalized for acute MI in the previous 6 months. Patients underwent myocardial perfusion imaging at rest, after mental stress (speech task), and after exercise or pharmacological stress. A summed difference score (SDS), obtained with observer-independent software, was used to quantify myocardial ischemia under both stress conditions. The Beck Depression Inventory-II (BDI-II) was used to measure depressive symptoms, which were analyzed as overall score, and as separate somatic and cognitive depressive symptom scores. Results There was a significant positive association between depressive symptoms and SDS with mental stress, denoting more ischemia. After adjustment for demographic and lifestyle factors, disease severity and medications, each incremental depressive symptom was associated with 0.14 points higher SDS. When somatic and cognitive depressive symptoms were examined separately, both somatic [β = 0.17, 95% CI: (0.04, 0.30), p = 0.01] and cognitive symptoms [β = 0.31, 95% CI: (0.07, 0.56), p = 0.01] were significantly associated with mental stress-induced ischemia. Depressive symptoms were not associated with ischemia induced by exercise or pharmacological stress. Conclusion Among young post-MI patients, higher levels of both cognitive and somatic depressive symptoms are associated with a higher propensity to develop myocardial ischemia with mental stress, but not with physical (exercise or pharmacological) stress.
The John Charnley Award: Risk Factors for Cup Malpositioning: Quality Improvement Through a Joint Registry at a Tertiary Hospital

Background Few studies have examined factors that affect acetabular cup positioning. Since cup positioning has been linked to dislocation and increased bearing surface wear, these factors affecting cup position are important considerations.
Algebraic signal processing theory: Cooley–Tukey type algorithms on the 2-D hexagonal spatial lattice

Recently, we introduced the framework for signal processing on a nonseparable 2-D hexagonal spatial lattice including the associated notion of Fourier transform called discrete triangle transform (DTT). Spatial means that the lattice is undirected in contrast to earlier work by Mersereau introducing hexagonal discrete Fourier transforms. In this paper we derive a general-radix algorithm for the DTT of an n × n 2-D signal, focusing on the radix-2 × 2 case. The runtime of the algorithm is O(n 2 log(n)), which is the same as for commonly used separable 2-D transforms. The DTT algorithm derivation is based on the algebraic signal processing theory. This means that instead of manipulating transform coefficients, the algorithm is derived through a stepwise decomposition of its underlying polynomial algebra based on a general theorem that we introduce. The theorem shows that the obtained DTT algorithm is the precise equivalent of the well-known Cooley–Tukey fast Fourier transform, which motivates the title of this paper. It is with great sadness that the authors contribute this paper to this special issue in memory of their former PhD advisor Thomas Beth. Beth was an extremely versatile researcher with contributions in a wide range of disciplines. However, one pervading theme can be identified in all of his work: the belief that mathematics, and in particular abstract algebra, was the language and key to uncovering the structure in many real world problems. One testament to this vision is his seminal habilitation thesis on the theory of Fourier transform algorithms, which ingeniously connects one of the principal tools in signal processing with group theory to open up an entirely new field of research. The authors deeply regret that Beth’s untimely death prevented him from seeing the Algebraic Signal Processing Theory, a body of work, including the present paper, that develops an axiomatic approach to and generalization of signal processing based on the representation theory of algebras. The theory is a logical continuation of Beth’s ideas and would not exist without him and his influence as PhD advisor. The authors like to think that he would have approved of this work and wish to dedicate this paper to him and his memory.
Prolonged complete responses and near-complete responses to sunitinib in metastatic renal cell carcinoma.

Sunitinib is a tyrosine kinase inhibitor with activity against vascular endothelial growth factor (VEGF) receptor and platelet-derived growth factor receptor recently approved by the FDA for the treatment of advanced renal cell carcinoma (RCC). Complete responses (CRs) to sunitinib have been documented in the literature. However, a detailed description and analysis of these patients is lacking. Seventy-four patients receiving sunitinib at the Cleveland Clinic in first-, second-, and third-line clinical trials were reviewed to determine the number of patients with Response Evaluation Criteria in Solid Tumors (RECIST)-defined CRs and patients who have achieved near CRs (nCRs) with a > 90% reduction in composite tumor volume or residual disease of 22 months while on maintenance sunitinib. The patients who obtained CRs had nonbulky pulmonary metastases, had favorable or intermediate Memorial Sloan-Kettering Cancer Center risk profiles, were treated with sunitinib in the first-line setting, and had a significant reduction in composite tumor measurements within the first 2 cycles. Two additional patients achieved nCRs, including a patient who had previously progressed on bevacizumab. Finally, 1 patient achieved sufficient downstaging and reduction of tumor volume such that the remaining lesion could be excised to produce a surgical CR. Sunitinib is capable of producing durable CRs in patients with cytokine-naive, metastatic RCC who have nonbulky pulmonary metastases. Additionally, nCRs can be seen despite nonpulmonary metastatic sites and previous VEGF-targeted therapy.
Extrusion of copper clad aluminum wire

Abstract This report describes investigation in the extrusion of copper clad aluminum wire. The variables that influence a sound clad extrusion are determined. These variables are (1) die design, (2) extrusion ratio, (3) extrusion pressure, (4) product velocity, (5) percentage copper used, and (6) ratio of flow stress of copper to aluminum. These investigations show that: (1) Successful clad extrusions may be achieved with a die angle in the range of 70° to 113°. (2) Extrusion ratios of 100:1 are possible. (3) Extrusion pressures for 15% copper performs may be written as P = 72.0 + 173 log e (A i/ A f (MPa) (4) A product velocity of about 350 fpm (1.78 m/s) seems to be the limit for sound extrusions. (5) Billets with 10% copper may be extruded with the same facility as 15% copper bars. (6) Higher extrusion ratios are possible with a core of hard drawn aluminum than with an annealed core.
Photoacoustic and ultrasound imaging contrast enhancement using a dual contrast agent

The complementary information provided by the ultrasound and photoacoustic imaging modalities has sparked their use in combination in recent years. We introduce a dual contrast agent capable of providing image contrast enhancement for both modalities simultaneously. The dual contrast agent is a small liquid perfluorocarbon droplet encased with bovine serum albumin and loaded with plasmonic nanoparticles. The plasmonic metal nanoparticles themselves act as a photoacoustic contrast agent. Furthermore, the perfluorocarbon droplet creates acoustic impedance mismatch between itself and the surrounding tissue, allowing it to act as an ultrasound contrast agent. Experiments demonstrating the performance of this dual contrast agent in ultrasound and photoacoustic imaging are presented. Differences in contrast mechanisms of the dual agent are highlighted, and finally, the applications for the agent are discussed.
Platelet count ratio (PCR) as an additional parameter in the quantitation of platelet aggregation in vitro.

Abstract An additional parameter, the platelet count ratio (PCR), has been introduced to describe further platelet aggregation as determined by nephelometric measurements. This parameter is the ratio of the count of individual platelets a specified time after the addition of an aggregating agent to the original platelet count of the plateletrich plasma with stabilization of the systems by fixation of the platelets with glutaraldehyde. The value of the PCR was assessed for approximately 40 platelet-rich plasma samples from 37 healthy human male and female donors. The application of the PCR was explored in studies on the in vitro aggregation of platelets induced by ristocetin, collagen and adenosine diphosphate (ADP).
I do not feel I am properly trained to help them! Rural teachers’ perceptions of challenges and needs with English-language learners

This paper explores the perceived professional development needs of inservice teachers of English-language learners (ELLs) from 10 rural and small districts in the USA. The survey instrument that captured responses from 159 elementary and secondary teachers in Texas was primarily quantitative and was based on the state English as a second language (ESL) certification examination. It also included open-ended demographic information on teachers’ backgrounds, and elicited information on challenges in working with ELLs. Demographics of the respondents reflect a typical teaching force in the rural USA: primarily white, English-speaking females with a bachelor’s degree. For many of the teachers, communication with students and their parents was cited as a major challenge. One of the most salient findings occurred in correlations between teachers having taken one or more college courses in ESL and their perceived knowledge of the competencies involved in the ESL examination. This important insight suggests that ...
Sleep state effects on breathing after spinal cord transection and vagotomy in the cat.

Abstract The role of chest wall and vagal afferents on breathing during wakefulness (W), nonrapid eye movement sleep (NREM), and REM sleep was assessed in 16 adult cats implanted with electrodes and skull bolts for sleep recordings with head restraint. Breathing was monitored with a pneumotachograph. Following control recordings establishing characteristic respiratory patterns during each state, cats sustained spinal cord transections at T-1, vagotomies, or both. The transections decreased variability of breathing rate, while vagotomies decreased rate but increased variability and tidal volume. These deafferentations alone or in combination failed to eliminate the major effects of state upon breathing pattern. Different states of consciousness were associated with significant changes on every measured breathing parameter, but the interactions of these effects with deafferentations were small or nonsignificant. The vagus, however, appears to play its largest role during NREM. We hypothesize that while afference functions during all states to terminate inspiration, during W and REM separate but functionally equivalent mechanisms of central origin supplement the vagus in facilitating the termination of inspiration. The absence of these mechanisms during NREM accounts for the increased vagal influence during this state.
Follow-up care instructions, treatment summaries, and cancer survivors’ receipt of follow-up health care and late/long term effects

Cancer survivors need follow-up care. Survivorship care plans (SCP), including follow-up care instructions (FCI) and treatment summaries (TS), were designed to improve cancer survivors’ receipt of follow-up care after cancer treatment. However, there is a paucity of evidence regarding the relationship between survivors’ receipt of FCI and TS and their receipt of follow-up care and late/long term effects. This study used data from the 2010 LIVESTRONG online survey of people affected by cancer, including 3541 cancer survivors who had completed treatment. Receipt of FCI was associated with greater likelihood of attendance at all regular medical appointments (aOR 2.28, 95 % CI 1.60–3.23), receipt of cancer surveillance (aOR 1.64, 95 % CI 1.28–2.09), being up to date on preventive cancer screening (aOR 2.63, 95 % CI 2.00–3.47), and with fewer late/long term effects (IRR 0.77, 95 % CI 0.69–0.85). Receipt of TS was associated with greater likelihood of attendance at all regular medical appointments (aOR 1.79, 95 % CI 1.31–2.44) and being up to date on preventive cancer screening (aOR 1.43, 95 % CI 1.14–1.78), but not cancer surveillance or late/long term effects. This study is among the first to document the associations between SCP and survivors’ attendance at regular medical appointments, cancer surveillance, preventive cancer screenings, and late/long term effects. The findings suggest that SCP may facilitate follow-up care needed by cancer survivors after cancer treatment is completed.
Transverse myelopathy: Influence of body position as a cause

Abstract A 37-year-old man developed an acute onset of paraplegia after traveling about 412 hr in the cab of a moving truck, sitting "crouched over, Indian style," with trunk flexed forward and the lower extremities in flexion, abduction, and external rotation. A diagnosis of transverse myelitis with probable spinal cord infarct was made. The sudden onset in this case supports a vascular origin, with body position as an important factor leading to vascular compromise of the spinal cord.
Combinatorial filing schemes with fewer buckets and improved redundancy and construction characteristics

Abstract This paper presents an interesting extension of the combinatorial filing scheme approach to information retrieval. It is appropriate both in the traditional large secondary memory architecture for information retrieval and in the distributed computing paradigm of powerful but cheaper, smaller machines. An important characteristic of the proposed scheme, unlike other combinatorial ones, is that redundancy can be decreased by varying a parameter. Moreover, the construction process is significantly simpler, the number of buckets smaller and the choice of parameters greater than for the typical combinatorial schemes, all of which make this scheme an attractive information retrieval approach for today's technology. In particular, families of balanced multiple-valued filing schemes of order k over the projective geometry PG(t, q) are constructed. Certain (s + c)-flats formed from the union of distinct flats of a partial spread of order (s + 1), such that c ¦(t − s) and which pass through the s-flat Vs, are used to define the attributes and values. For order k queries, the buckets are the (k + h)-flats through a fixed h-flat, Vh, of PG(t, q), V h C V s . Storage and retrieval algorithms use difference set representation, and structural properties, of the bucket flats. The number of attributes and number of values per attribute are dependent on the values of s and c. The redundancy is made to vary with the value of h. A particular scheme of order k in the family is a balanced multiple-valued filing scheme, BMFSk, with parameters (s, c, h).
MORE ON USING FORCED IDLE TIME TO IMPROVE PERFORMANCE IN POLLING MODELS

A recent interesting paper (Cooper, Niu, and Srinivasan [2]) shows how for some cyclic production systems reducing setup times can surprisingly increase work in process. There the authors show how in these situations the introduction of forced idle time can be used to optimize system performance. Here we show that introducing forced idle time at different points during the production cycle can further improve performance in these situations and also in situations where the suggestions from [2] yield no improvement.
Radioautographic study of P32 and Ca45 uptake in jaws and knee joints of adult rats.

Abstract 1. 1. The role of inorganic ionic exchange in the complete metabolism of bone has not been established as yet to a degree that allows significant conclusions on metabolic activity based on radioactivity following administration of P32 and Ca45. 2. 2. The uptake of radioactive phosphorus and calcium in the alveolar bone in adult rats may be equal to, but it usually is less than, the uptake in endosteal bone surrounding marrow spaces and Haversian canals. 3. 3. The periodoutium in adult rat molars has a much higher uptake of radioactive phosphorus and calcium than periosteum, tendon attachments, ligaments, and adjacent bone. 4. 4. A marked variation in uptake of radioactive phosphorus and calcium was observed in various areas of the periodontal membrane. 5. 5. Radioautographs from Ca45 give much better photographic resolution than those from P32. 6. 6. The periodontal membrane is neither morphologically nor biologically comparable to periosteum or tendons elsewhere in the body.
The Changing Landscape of Clinical Psychology

This commentary on “Clinical Psychologists in the 2010s” by Norcross and Karpiak (2012) focuses on selected findings from a survey of members of the Society of Clinical Psychology conducted by the authors. The focus is primarily on findings related to changes in the theoretical orientation of members over time, increases in the number of women and racial/ethnic minorities members, as well as publication rates and career satisfaction levels of members. Findings of this survey are, in some instances, supplemented by findings obtained from the Division of Clinical Child and Adolescent Psychology and the Division of Pediatric Psychology to provide additional information regarding clinical psychologists who work with children.
SUT Sucrose and MST Monosaccharide Transporter Inventory of the Selaginella Genome.

While most metazoa mainly use hexose transporters to acquire hexoses from their diet and as a transport form for distributing carbon and energy within their bodies, insects use trehalose and plants use sucrose as their major form for translocation. Plant genomes contain at least three families of mono- and disaccharide transporters: monosaccharide/polyol transporters that are evolutionary closely related to the yeast and human glucose transporters, sucrose transporters of the SUT family, which similar to the hexose transporters belong to the major facilitator superfamily (MFS), but share only minimal amino acid sequence homology to the hexose transporters, and the family of SWEET sugar transporters conserved between animals and plants. Recently, the genome sequence of the spikemoss Selaginella has been determined. In order to study the evolution of sugar transport in plants, we carried out a careful annotation of the complement of sugar transporters in Selaginella. We review what is known about sugar transport in spikemoss and provide phylogenetic analyses of the complement of MST and SUT homologs in Selaginella.
What Should Crypto Look Like

Usability failures are the leading technical cause of phishing attacks and unintended plaintext emails, and share much of the blame for the problems with the Web's PKI. The security community should pay more attention to what cryptography should look like.
Changes in fractal dimension during aggregation

Experiments were performed to evaluate temporal changes in the fractal dimension of aggregates formed during flocculation of an initially monodisperse suspension of latex microspheres. Particle size distributions and aggregate geometrical information at different mixing times were obtained using a non-intrusive optical sampling and digital image analysis technique, under variable conditions of mixing speed, coagulant (alum) dose and particle concentration. Pixel resolution required to determine aggregate size and geometric measures including the fractal dimension is discussed and a quantitative measure of accuracy is developed. The two-dimensional fractal dimension was found to range from 1.94 to 1.48, corresponding to aggregates that are either relatively compact or loosely structured, respectively. Changes in fractal dimension are explained using a conceptual model, which describes changes in fractal dimension associated with aggregate growth and changes in aggregate structure. For aggregation of an initially monodisperse suspension, the fractal dimension was found to decrease over time in the initial stages of floc formation.
Effects of Residual Stresses and the Post Weld Heat Treatments of TIG Welded Aluminum Alloy AA6061-T651

Heat treatable AA-6061 T651 Aluminum alloys (Al-Mg-Si) have found considerable importance in various structural applications for their high strength to weight ratio and corrosion resistance properties. Weld defects, residual stresses, and microstructural changes are the key factors for the performance reduction as well as failure of welded structures. Tungsten inert gas (TIG/GTAW) welding was carried out on AA-6061 T651 Aluminum Alloy plates using Argon/Helium (50/50) as the shielding gas. Non-destructive phased array ultrasonic testing (PAUT) was applied for the detection and characterization of weld defects and characterization of the mechanical performances. In this study, ultrasonic technique was also used for the evaluation of post-weld residual stresses in welded components. The approach is based on the acoustoelastic effect, in which ultrasonic wave propagation speed is related to the magnitude of stresses present in the materials. To verify the estimated residual stresses by ultrasonic testing, hole-drilling technique was carried out and observed analogous results. The effects of post weld heat treatment (PWHT) on the residual stresses, grain size, micro hardness, and tensile properties were also studied. The grain size and micro hardness were studied through Heyn’s method and Vickers hardness test, respectively. Lower residual stresses were observed in post-weld heat-treated specimens, which also experienced from microstructure and micro hardness studies. The PWHT also resulted enhanced tensile properties for the redistribution of microstructures and residual stresses.Copyright © 2012 by ASME
Hexagonal crystalline inclusion complexes of 4-iodophenoxy trimesoate

Bifurcated I⋯π and I⋯OC halogen bonding interactions assist in formation of unique iodo–arene trimers leading to nanoscale channels in inclusion complexes of trimesic acid iodophenolate.
Body Perception and Somatic Discomfort in Relation to Right- Versus Left-Handedness

Multiple studies analyzed differences in body perception and body complaints between right- and left-handed subjects. Both male and female samples were included. The findings indicated that the left-handed exceeded the right-handed in feelings of body security and degree of body boundary differentiation. In addition, handedness was shown to be linked with different modes of distributing attention to the major sectors of one's body. An adequate explanation of the link between handedness and body perception is not at present available.
Mannose-specific recognition mediates two aspects of synaptic growth of leech sensory afferents: Collateral branching and proliferation of synaptic vesicle clusters

Abstract The developmental role of carbohydrate markers in the genesis of neuronal networks was studied using leech sensory afferents as a model. Leech sensory afferents express a mannose-containing epitope on their cell surface that is recognized by monoclonal antibody Lan3-2. Previously, the elaboration of sensory arbors in the synaptic neuropil of CNS ganglia was experimentally shown to depend on this mannose marker. Sensory arbors were abolished by perturbing sensory afferents in the intact nervous system with Lan3-2 Fab fragments, a glycosidase, or mannose–BSA. To understand the cytological mechanisms underlying mannose-specific recognition for synaptogenesis, we have now studied the effects of antibody perturbation at the ultrastructural level in the sensory afferent target region. A characteristic signature of a normal sensory afferent is its profuse collateral branching, which, with ongoing development, is replaced by a single widened process, the sensory trunk, which possesses numerous synaptic vesicle clusters. The inhibition of mannose-specific recognition leads to a rapid, major reorganization of different stages of sensory afferent growth. Collateral branches at the distal growing region are reduced three- to fourfold. The pruned axons grow at an accelerated rate. Developmentally older sensory trunks experience a threefold reduction in synaptic vesicle clusters. These responses suggest that depriving sensory afferents of mannose-specific recognition aborts their synaptogenesis and causes them to resume behavior typical of tracking through axonal tracts. The current findings also suggest that the mannose marker, by promoting both collateral branching andthe proliferation of synaptic vesicle clusters, plays a critical role in two stages of sensory afferent synaptogenesis.
Adaption of team learning to an introductory graduate pharmacology course.

Background: Team-learning experiences within a large group setting have a variety of educational applications. Description: Aspects of the team-learning process were introduced into the endocrine pharmacology unit of an introductory graduate pharmacology course. Each session involved both a faculty lecture and student participation in problem-solving exercises. Curriculum design, small group assignments, instructional materials, small group activities, assessment, student opinions, and cost-benefit considerations were evaluated. Evaluation: The effects of team-learning strategies on student participation during class, preparation before class, and student perception were examined using a student feedback instrument, instructor perceptions, and comparison of student performances in the unit and the course, as well as personal interviews with students. Conclusion: The use of team learning was appreciated by the students and instructor. Students strongly believed that the team-learning component improved the...
Transcript expression in endometrial cancers from Black and White patients

Abstract Objective Previous studies suggest that differences in molecular features of endometrial cancers between racial groups may contribute to the poorer survival in Blacks. The objective of this investigation was to determine whether gene expression among endometrial cancers is different between Blacks and Whites. Methods Fresh frozen tumors from 25 Black patients were matched by stage, grade, and histology to endometrial cancer specimens from 25 White patients. Each case was macrodissected to produce specimens possessing a minimum of 75% cancer cellularity. A subset of 10 matched pairs was also prepared using laser microdissection (LMD) to produce specimens possessing a minimum of 95% cancer cells. Total RNA isolated from each sample was analyzed using the Affymetrix Human Genome U133 Plus 2.0 arrays. Data were analyzed using principal component analysis and binary class comparison analyses. Results Unsupervised analysis of the 50 endometrial cancers failed to identify global gene expression profiles unique to Black or White patients. In a subset analysis of 10 matched pairs from Blacks and Whites prepared using LMD and macrodissection, unsupervised analysis did not reveal a unique gene expression profile associated with race in either set, but associations were identified that relate to sample preparation technique, histology and stage. Conclusions Our microarray data revealed no global gene expression differences and identified few individual gene differences between endometrial cancers from Blacks and Whites. More comprehensive methods of transcriptome analysis could uncover RNAs that may underpin the disparity of outcome or prevalence of endometrial cancers in Blacks and Whites.
Geochemical evidence for magmatic water within Mars from pyroxenes in the Shergotty meteorite

Observations of martian surface morphology have been used to argue that an ancient ocean once existed on Mars1. It has been thought that significant quantities of such water could have been supplied to the martian surface through volcanic outgassing, but this suggestion is contradicted by the low magmatic water content that is generally inferred from chemical analyses of igneous martian meteorites2. Here, however, we report the distributions of trace elements within pyroxenes of the Shergotty meteorite—a basalt body ejected 175 million years ago from Mars3—as well as hydrous and anhydrous crystallization experiments that, together, imply that water contents of pre-eruptive magma on Mars could have been up to 1.8%. We found that in the Shergotty meteorite, the inner cores of pyroxene minerals (which formed at depth in the martian crust) are enriched in soluble trace elements when compared to the outer rims (which crystallized on or near to the martian surface). This implies that water was present in pyroxenes at depth but was largely lost as pyroxenes were carried to the surface during magma ascent. We conclude that ascending magmas possibly delivered significant quantities of water to the martian surface in recent times, reconciling geologic and petrologic constraints on the outgassing history of Mars.
Some Ceramic Properties of Halloysite

The analysis of four clays originating in Utah indicates that they consist almost entirely of the mineral halloysite. Extruded specimens of these clays show particle alignment and on firing produce large differential shrinkages. The properties of one of the clays were investigated after a low-temperature calcination process. In all cases excessive shrinkages were observed that may be explained on the basis of particle structure.
Occupational therapy goal achievement for persons with postacute cerebrovascular accident in an on-campus student clinic.

OBJECTIVES A retrospective study was conducted to determine to what extent persons with postacute cerebrovascular accident (CVA) made progress toward rehabilitation goals during occupational therapy treatment and whether age and time since CVA onset affected the rate of goal achievement. METHOD Data were collected from the admission and discharge records of persons with CVA who had received occupational therapy at a university clinic, who were at least 8 months post CVA, and who had not received therapy in the community for at least 6 months. The treatment was provided by occupational therapy students under supervision and had a mean length of 12 1-hr sessions over one semester. A sample size of 85 was obtained from 13 years of clinic records. RESULTS All patients in the sample except one made progress toward at least one of their selected rehabilitation goals. The group mean score for goal progress indicated that as a whole, the patients made significant gains. In addition, independent t tests showed no significant differences in mean scores between younger and older patients, between longer and shorter times since onset, between men and women, or between right and left CVA. There was no significant linear association between mean score and the number of treatments received. CONCLUSION Patients with CVA showed progress toward rehabilitation goals during postacute treatment. Patients with recent CVA onset or of younger age did not achieve goals at a significantly higher rate than those with less recent onset or of greater age.
Global well-posedness of dissipative quasi-geostrophic equations in critical spaces

We prove global well-posedness for the dissipative quasi-geostrophic equation with initial data in critical Besov spaces B1+1/p-2α p,q, 0 < α ≤ 1, provided that the B1+2/p-2α p,q norm of the initial data is sufficiently small compared with the dissipative coefficient κ.
The NII 2143 A emission in the dayglow

Observations of the N II 2143 A emission in the earth's dayglow were obtained by a rocket-borne spectrograph flown on Nov. 9, 1981, and Aug. 11, 1982. The ultraviolet spectra were analyzed using synthetic spectra to separate the contribution of the 2143 A emission from the overlapping nitric oxide gamma band. The 2143 A column emission rate profiles for both flights were quite similar with peak column emission intensities of approximately 500 Rayleighs at an altitude of 160 km. When the observed column emission rate profiles were compared with theoretical calculations, the production efficiency of this emission was found to be 0.10 + or - 0.04. The 2143 A emission varies by more than a factor of 3 over the solar cycle and therefore should be useful as an indicator of the solar EUV flux.