cssi/SciSciGPT-SciSciNet huggingface dataset:
Low-power and high-sensitivity system-on-chip hall effect sensor

Low-cost, low-power, and high-sensitivity System-on-Chip (SoC) Hall Effect sensors for 0.18μm and 0.13μm technologies and beyond are developed in this work. A best-inclass current-related sensitivity Si of 418 V/A∗T is achieved by a Hall device with an area of 42 μm × 42 μm. Small offset voltage ranges within +/−1.05 mV, as well as excellent sensor reliability, are demonstrated. The Hall sensors are available for manufacturing.
Practical Strategies for Enhancing Doctoral Students' Preparedness to Teach

Doctoral education programs in physical education teacher education have a responsibility to train aspiring faculty members to be effective researchers and good teachers. Using occupational sociali...
Nanoparticles from Amphiphilic Heterografted Macromolecular Brushes with Short Backbones

Heterografted macromolecular brushes are highly grafted macromolecules with two different side chains attached to a backbone. When endowed with an amphiphilic character, these can serve as unique stabilizers of biphasic systems and solute carriers and yield interesting self-assembled structures. Herein, we report on the solution structure of amphiphilic double-brush copolymers with short backbones—i.e., comparable to the length of the side-chains—in a selective solvent for one of the grafted blocks. As determined by small-angle neutron scattering measurements, poly(ethylene glycol)/poly(d,l-lactide) double brushes adopt a cylindrical structure with highly extended backbones in DMSO. In contrast, brushes undergo intermolecular self-assembly into spherical nanoparticles in water, with aggregation numbers that vary inversely with backbone degree of polymerization. While considerably less susceptible to intermolecular association than linear diblocks of similar hydrophobic and hydrophilic block lengths, the i...
Managing Raptors to Reduce Wildlife Strikes at Chicago's O'Hare Interna- tional Airport

Wildlife-aircraft collisions (wildlife strikes) have increased nationally over the past 22 years; denoted in the National Wildlife Strike Database that has been maintained by the Federal Aviation Administration (FAA) since 1990. Increasing wildlife populations and air traffic coupled with quieter, faster aircraft create a significant risk to aviation safety; the cost to the civil aviation industry is an esti- mated $718 million dollars annually. USDA/APHIS/Wildlife Services provides technical and direct as- sistance to over 785 airports and airbases around the United States, including Chicago's O'Hare Interna- tional Airport (ORD). At ORD, raptors are the most commonly struck bird guild accounting for 25% of all damaging strikes in 2011. An integrated wildlife damage management program is implemented at ORD to reduce the presence of wildlife on the airfield, consequently lowering the risk of wildlife strikes. Professional airport wildlife biologists at ORD concentrate much of their efforts on raptor damage man- agement due to the high strike risk these birds pose to aircraft on the airfield itself. A variety of tech- niques are currently used to manage raptor populations at ORD.
Portal hypertension correlates with splenic stiffness as measured with MR elastography.

Purpose To investigate the correlation between MRE assessed spleen stiffness and direct portal vein pressure gradient (D-HVPG) measurements in a large animal model of portal hypertension.
Site-Directed Mutagenesis in the Mouse

Publisher Summary This chapter presents site-directed mutagenesis in the mouse. The correlation of genotype and phenotype is a central theme in the analysis of development. In the mouse, this type of reverse genetics is constrained not only by the size of the murine genome, which makes positional cloning difficult, but also by the limited availability of mutations that can readily be identified and maintained. A number of mutations in mice have been correlated with cloned genes. Mapping and attempting to identify mutations in candidate genes is clearly limited by the availability of mutations. Another approach to link phenotype to genotype is by using transgenic insertions that have mutated endogenous genes as a result of the integration of the transgene. Though each approach is uniquely important, one of the values of the genetic approach is the ability to generate an allelic series of mutations that functionally dissect a genetic locus. Very recently, it has become possible to generate mutant mice for virtually any cloned gene by implementing embryonic stem (ES) cell/gene targeting technologies. The combination of ES cells and gene targeting techniques constitutes a very powerful genetic system. The application of these methodologies to recently isolated ES cell lines has led to a much higher frequency of chimera formation and germ line transmission than was previously possible.
Estimating extent of mortality associated with the Douglas-fir beetle in the Central and Northern Rockies

Data collected from Douglas-fir stands infected by the Douglas-fir beetle in Wyoming, Montana, Idaho, and Utah, were used to develop models to estimate amount of mortality in terms of basal area killed. Models were built using stepwise linear regression and regression tree approaches. Linear regression models using initial Douglas-fir basal area were built for all study sites but produce low precision estimates. Regression tree models using initial Douglas-fir basal area of stand density index or both were also build for all sites. Regression tree models provide a more realistic approach to estimate potential mortality by creating more homogenous mortality classes with reduced variance. The models developed provide land managers with a basis for determining the potential mortality should a Douglas-fir beetle outbreak develop.
Sexuality Education for Students Who Are Deaf: Current Practices and Concerns

A questionnaire was sent to all the Deaf Schools in the U.S. including State Deaf Schools, Private Deaf Schools, and Public Schools that were listed as having a program specifically for students who are deaf. Ninety-two questionnaires were mailed and 76 were returned for a response rate of 83%. The questionnaire elicited information regarding current practices in sexuality education including materials used, mode of communication, media materials utilized, topics covered, and the instructor's perception of the quality of materials being used. Results indicate that teachers are spending more than 2 hours per week modifying materials for their sexuality curriculum. Most of the respondents expressed concerns about obtaining materials that are accessible and appropriate for students who are deaf, developing an overall curriculum, obtaining materials for students who have multiple disabilities, and obtaining materials that do not require modification before they are used with students who are deaf.
Prospects and Problems in Electrochemical Engineering

Developments in electrochemical engineering science over the past 20–30 years have led to introduction of quantitative techniques for scale-up, design, and optimization of cell-processes. At the interface between the complex and heterogeneous field of electrochemistry, and chemical engineering, the electrochemical engineer faces a lack of basic information on phenomena occurring at electrode surfaces. This is especially evident in the case of simultaneous and consecutive component processes which involve changes in phase at electrodes: gas evolution, and electrocrystallization from the electrolyte or from another solid phase. New efforts are needed in the direction of characterizing processes, in the quasi steady state, which continue over long periods of time. Direct physical observation and interpretation of key phenomena, such as crystal growth, bubble dynamics, change in state of aggregation of catalysts, and, in general, the characterization of changing surface properties in situations corresponding to industrial process conditions, are needed if we are to further improve material- and energy-efficiency, and to reduce capital and labor costs.
Using visualization to teach security

Interactive visualization tools have been shown to be an effective means for engaging students in the learning process. Information security is a complex topic that can benefit from judicious design and application of classroom visualizations. At our institution, we have developed a series of interactive visualizations to teach students security concepts in different courses at different levels of experience. This paper describes the approach used to design and implement the visualizations, their use in the classroom, and our experience with their effectiveness in increasing student understanding.
Leading Change: Developing Emotional, Social, and Cognitive Competencies in Managers During an MBA Program

A number of social, emotional, and cognitive competencies have been shown to predict management, professional, and leadership effectiveness. Can these competencies be developed through graduate management education? This chapter provides an update on the 25-year empirical investigation conducted at the Weatherhead School of Management, Case Western Reserve University, to explore patterns and sustainability of competency development in a full-time MBA program before and after it was enriched with the Leadership Assessment and Development (LEAD) course. Comparisons of MBA students’ self- and other-rated competency assessments at graduation with the same assessments conducted at the time of entry into the program were examined in cohorts from 1987 to 1990 (pre-LEAD) and 1990 through to 2013 (post-LEAD), the last 5 years of which have never been published. In addition to updating and extending the findings of prior publications of this research program, this chapter aimed to open the discussion on the emotional and social competencies which have been shown not to improve over time and to offer suggestions for management educators around the world.
Butler’s Monsters: The Grotesque and the Black Communal Body in Octavia Butler’s Dawn

The ugly, grotesque alien is one of science fiction’s most enduring tropes. Where usually this ugly alien is the embodiment of evil, science fiction writer Octavia Butler refuses to represent it as a single-dimensional being. While she constructs insectoid and many-tentacled beings that might feel physically familiar as monsters, she endows them with humanity and intertwines them with humans in relationships that muddy the waters of power, consent, repulsion, and desire. This chapter argues that Butler’s “creepy crawlies” point the way towards a black feminist-queer politics of the grotesque, which troubles a linear theory of liberation just as it does the concept of an integral community. It examines Butler’s revisions of two figures, the ugly alien and the traitorous black matriarch, as they are articulated in Dawn, the first novel of the Xenogenesis series. By connecting these figures both figuratively and materially, Butler calls into question a post-Black Power movement nationalist discourse that premises hetero-normativity and properly disciplined womanhood as conditions for community progress. By opening the human body to queering disruptions, Butler proposes that we rethink the desirability of the black communal body—a beautiful, orderly being that must present its best face to the world.
Phenomenology of Modified Gravity at Recombination

We discuss the phenomenological imprints of modifications to gravity in the early Universe with a specific focus on the time of recombination. We derive several interesting results regarding the effect that such modifications have on cosmological observables, especially on the driving and phasing of acoustic oscillations, observed in the cosmic microwave background (CMB) and baryon acoustic oscillations, as well as the weak gravitational lensing of the CMB and of galaxy shapes. This widens the pool of measurements that can be used to test gravity with present and future surveys, in particular realizing the full constraining power of the structure of the primary peaks of the CMB spectrum. We investigate whether such a phenomenology can relax tensions between cosmological measurements and find that a modification of the gravitational constant at recombination would help in reconciling measurements of the CMB with local measurements of the Hubble constant.
Facilitating Physical Activity with Individuals with Marfan Syndrome

Individuals with Marfan syndrome possibly unknowingly participate in certain physical activities and sports, putting themselves at risk for aortic dissection. However, with appropriate diagnosis an...
Weather: A Concise Introduction

From a world-renowned team at the Department of Atmospheric Sciences at the University of Washington, Seattle, Weather: A Concise Introduction is an accessible and beautifully illustrated text covering the foundations of meteorology in a concise, clear, and engaging manner. Designed to provide students with a strong foundation in the physical, dynamical, and chemical processes taking place in the atmosphere, this introductory textbook will appeal to students with a wide range of mathematical and scientific backgrounds. This textbook features: a single case study of a mid-latitude cyclone which is referred to throughout the whole book to illustrate the basic principles driving atmospheric dynamics and phenomena; boxes on more advanced topics; appendices for additional coverage; chapter summaries listing the 'take-home' points discussed; and colour figures and charts illustrating the fundamental concepts. Key terms are evident throughout, and a glossary explains the terms that students will need to understand and become familiar with.
Effect of sodium nitroprusside in treatment of hand, foot and mouth disease due to enterovirus 71 in hypotensive phase

Objective To investigate the curative effect of sodium nitroprusside in the treatment of EV71-related pneumoedema/pneumorrhagia and hypotension in this study. Methods This was a retrospective study of a total 10 children with EV71-related pneumoedema/pneumorrhagia treated with sodium nitroprusside using case-control methods. The clinical manifestations and outcomes of the 10 children (present cohort) were compared with those of 8 children (past cohort) who had EV71-related pneumoedema/pneumorrhagia without sodium nitroprusside. Results Among these 10 patients,all were at the appearance of pneumoedema/pneumorrhagia, cardiac arrhythmia and hypotension. Two patients showed severe cardiac arrhythmia, two patients showed cardiac arrest for many times. All 10 patients were treated with mechanical ventilation and other conventional treatments. At the first time of the manifest of hypotension,sodium nitroprusside were put into practice in all 10 patients. Ten patients were treated with intravenously sodium nitroprusside in the stage of hypotension by maxi30 min ～ 1 h,the patients showed an improvement in vultus,pulse and peripheral circulation and decrease of heart rate and elevation of blood pressure after 30 min ～2 h,but at least 2～6 h later,the blood pressure tended to stabilize at normal standard. Conclusion Hypotension is the intensive stage in EV71-related hand,foot and mouth disease ,and the shock syndrome caused by acute left ventricular disorder is related to sympathetic nerve activity. Sodium nitroprusside can effectively reduce the cardiac afterload,and correct shock and improve the prognosis. Key words: Enterovirus 71 ; Hypotension; Cardiopulmonary failure; Sodium nitroprusside; Hand-foot-mouth disease
ECG Biometric Authentication: A Comparative Analysis

Robust authentication and identification methods become an indispensable urgent task to protect the integrity of the devices and the sensitive data. Passwords have provided access control and authentication, but have shown their inherent vulnerabilities. The speed and convenience factor are what makes biometrics the ideal authentication solution as they could have a low probability of circumvention. To overcome the limitations of the traditional biometric systems, electrocardiogram (ECG) has received the most attention from the biometrics community due to the highly individualized nature of the ECG signals and the fact that they are ubiquitous and difficult to counterfeit. However, one of the main challenges in ECG-based biometric development is the lack of large ECG databases. In this paper, we contribute to creating a new large gallery off-the-person ECG datasets that can provide new opportunities for the ECG biometric research community. We explore the impact of filtering type, segmentation, feature extraction, and health status on ECG biometric by using the evaluation metrics. Our results have shown that our ECG biometric authentication outperforms existing methods lacking the ability to efficiently extract features, filtering, segmentation, and matching. This is evident by obtaining 100% accuracy for PTB, MIT-BHI, CEBSDB, CYBHI, ECG-ID, and in-house ECG-BG database in spite of noisy, unhealthy ECG signals while performing five-fold cross-validation. In addition, an average of 2.11% EER among 1,694 subjects is obtained.
Optimal Convex Hull Formation on a Grid by Asynchronous Robots with Lights

We consider the distributed setting of n autonomous mobile robots that operate in Look-Compute-Move (LCM) cycles and communicate with other robots using a constant number of colored lights (the robots with lights model). We assume obstructed visibility where a robot cannot see another robot if a third robot is positioned between them on the straight line connecting them. In addition, we consider a grid-based terrain embedded in the 2-dimensional Euclidean plane that restricts each robot movement to one of the four neighboring grid points from its current position. This grid setting is a natural discretization of the 2-dimensional real plane and extends the robot swarm model in directions of greater applicability. The Convex Hull Formation problem is to relocate the n robots (starting at arbitrary, but distinct, initial positions) so that each robot is positioned on a vertex of a convex hull. In this paper, we provide two asynchronous algorithms for Convex Hull Formation, both using a constant number of colors. Key measures of the algorithms’ performance include the time taken and the space occupied (measured as the perimeter of the smallest rectangle enclosing the convex hull formed). The first O(max{n2, D})-time and O(n2)-perimeter algorithm serves to introduce key ideas, where D is the diameter of the initial configuration. The second algorithm runs in $O\left( {\max \left\{ {{n^{\frac{3}{2}}},D} \right\}} \right)$ time with a perimeter of $O\left( {{n^{\frac{3}{2}}}} \right)$. We also prove lower bounds of $\Omega \left( {{n^{\frac{3}{2}}}} \right)$ for both the time and perimeter for any Convex Hull Formation algorithm; that is, we establish our second algorithm as optimal in both time and perimeter.
Shaping Regional Economies to Sustain Quality Work: The Cooperative Health Care Network

This chapter chronicles a creative response to social retrenchment, a saga of strategic deployment of accessible resources and a reshaping of regional economic forces for the benefit of targeted labor markets. While charting its own course, CHCB is part of a mutually supportive network of health care employers and trainers, including successful home care companies in Philadelphia and the South Bronx. Together, these three corporations form the core of the Cooperative Health Care Network and employ over 500 home health aides. About 80 percent of the employees were formerly dependent on public assistance. The network [network] experience and their applicability to other employer initiatives or to broader public policy.
Posterior Simulation and Monte Carlo Methods

A beauty of the Bayesian approach is the principled nature of inference. There is a gold standard of how to proceed, and the basic principle is easily explained. However, the actual implementation often gives rise to many challenges. One of the challenges that remains an important research frontier of Bayesian inference is the problem of numerically evaluating the desired posterior summaries. In this chapter we review some related specific research problems.
The Influence of Regulation Affecting Non-GAAP Reporting on Executive Compensation Contracting

The regulatory landscape for non-GAAP reporting has been evolving due to changes in the U.S. SEC’s interpretations of regulations affecting non-GAAP disclosures. I examine whether the regulation of non-GAAP disclosures constrains efficient compensation contracting. I use the regulatory shock of the January 2010 update by the U.S. SEC to its interpretive guidance on non-GAAP disclosures, which some believe relaxed the bar for non-GAAP reporting. Using a novel hand-collected dataset on non-GAAP measures used by S&P 900 firms over the period from 2007 to 2017 and a difference-in-differences estimation approach, I find that firms with strong incentives to use non-GAAP measures in CEO incentive plans started using more of these measures after the guidance update to those that did not. I also find that this increase was more pronounced among firms with a higher propensity to fail a non-GAAP regulatory test in fiscal years 2010-11, which was relaxed after the update. Based on the history of regulations affecting the use of non-GAAP performance metrics and their specific applicability to non-GAAP measures used for contracting and valuation, I conclude that these effects are largely an unintended consequence of SEC rulemaking.
Amplifying Perspectives: The Experience of Adolescent Males of Color Engaged in School-Based Art Therapy

Abstract This qualitative study examines the experience of adolescent males of color engaged in a 12-week, school-based art therapy intervention. Participants were 78 ninth graders from limited resource communities attending an all-boys high school in the South Bronx, New York. The population was naturally divided into three groups based on levels of potential academic competency. At the conclusion of the intervention, participants completed a written questionnaire to ascertain their perspectives on art therapy, the pieces they created, and how process and product related to emotions. Qualitative coding revealed nine themes, which provided a sense of differential impacts of the intervention by academic grouping. Findings suggest that art therapy targets a range of needs for high school students, from those who are successful and feel positively in school to those who struggle within the academic setting.
WE-D-BRA-06: IMRT QA with ArcCHECK: The MD Anderson Experience

Purpose: The objective of this project was to report our initial IMRT QA results and experience with the SunNuclear ArcCHECK. Methods: Three thousand one-hundred and sixteen cases were treated with IMRT or VMAT at our institution between October 2013 and September 2014. All IMRT/VMAT treatment plans underwent Quality Assurance (QA) using ArcCHECK prior to therapy. For clinical evaluation, a Gamma analysis is performed following QA delivery using the SNC Patient software (Sun Nuclear Corp) at the 3%/3mm level. QA Gamma pass rates were analyzed based on categories of treatment site, technique, and type of MLCs. Our current clinical threshold for passing a QA (Tclin) is set at a Gamma pass rate greater than 90%. We recorded the percent of failures for each category, as well as the Gamma pass rate threshold that would Result in 95% of QAs to pass (T95). Results: Using Tclin a failure rate of 5.9% over all QAs was observed. The highest failure rate was observed for gynecological (22%) and the lowest for CNS (0.9%) treatments. T95 was 91% over all QAs and ranged from 73% (gynecological) to 96.5% (CNS) for individual treatments sites. T95 was lower for IMRT and non-HD (high definition) MLCs at 88.5% and 94.5%, respectively, compared to 92.4% and 97.1% for VMAT and HD MLC treatments, respectively. There was a statistically significant difference between the passing rates for IMRT vs. VMAT and for HD MLCs vs. non-HD MLCs (p-values << 0.01). Gynecological, IMRT, and HD MLC treatments typically include more plans with larger field sizes. Conclusion: On average, Tclin with ArcCHECK was consistent with T95, as well as the 90% action level reported in TG-119. However, significant variations between the examined categories suggest a link between field size and QA passing rates and may warrant field size-specific passing rate thresholds.
The Optional Protocol to the Convention on the Rights of the Child on the Sale of Children, Child Prostitution and Child Pornography and the Jurisprudence of the Committee on the Rights of the Child

The paper discusses the content of the Optional Protocol on the Sale of Children, Child Prostitution and Pornography. It analyzes the provisions of this Optional Protocol to the Convention on the Rights of the Child (herein referred to as the CRC or the Convention), and integrates them with the jurisprudence of the Committee on the Rights of the Child (herein referred to as the Committee). The paper highlights the main issues covered in the text of this Optional Protocol. These include: definition and criminalization of the offence; jurisdiction, extradition and further matters of criminal procedure; prevention; protection of victims and their rehabilitation; and the importance of international cooperation in the fight against sale of children, child prostitution and child pornography. The paper then more closely examines the Concluding Observations of the Committee on States Parties’ reports. Comparing the content of the Protocol with the observations of the Committee enables the identification of gaps between what is required and what has been done. At the same time, such a comparison allows for a discussion of some successful attempts at compliance. The paper concludes that the Committee’s jurisprudence has indeed provided useful guidance to the complex issues of the Protocol and helped in filling some of the gaps contained therein. Concurrently, however, it is found that many challenges remain with respect to the implementation of the Protocol’s provisions at national level.
Computational Aspects of Resilient Data Extraction from Semistructured Sources.

Automatic data extraction from semistructured sources such as HTML pages is rapidly growing into a problem of significant importance, spurred by the growing popularity of the so called ”shopbots” that enable end users to compare prices of goods and other services at various web sites without having to manually browse and fill out forms at each one of these sites. The main problem one has to contend with when designing data extraction techniques is that the contents of a web page changes frequently, either because its data is generated dynamically, in response to filling out a form, or because of changes to its presentation format. This makes the problem of data extraction particularly challenging, since a desirable requirement of any data extraction technique is that it be ”resilient”, i.e., using it we should always be able to locate the object of interest in a page (such as a form or an element in a table generated by a form fill-out) in spite of changes to the page’s content and layout. In this paper we propose a formal computation model for developing resilient data extraction techniques from semistructured sources. Specifically we formalize the problem of data extraction as one of generating unambiguous extraction expressions, which are regular expressions with some additional structure. The problem of resilience is then formalized as one of generating a maximal extraction expression of this kind. We present characterization theorems for maximal extraction expressions, complexity results for testing them, and algorithms for synthesizing them. ∗Work supported in part by the NSF grants CCR-9711386 and EIA-9705998.
Abstract 15974: Cardiac Magnetic Resonance Imaging Technique to Assess Constructive Myocardial Regeneration of a Tissue Engineered Cardiac Patch

Introduction: Extracellular matrix (ECM) scaffolds have been applied to repair myocardium. However the assessment of regional functions such as contractility and perfusion during remodeling process has not been well established. In this study, we evaluated the remodeled scaffolds using Cardiac Magnetic Resonance (CMR) with strain-encoding (SENC), rest perfusion, and T1 Mapping by modified Look-Locker inversion recovery for extracellular volume fraction (ECV) calculation. Methods and Results: The tissue-engineered cardiac patch, derived from porcine small intestinal submucosa ECM incorporated with basic fibroblast growth factor, was implanted into the porcine right ventricle (RV) to repair a surgically created full-thickness defect. CMR and histology was performed at 60 days post-implant. (N=4). Dacron patched pigs served as control (N=5; histology). Histology: Remodeled ECM consisted of well-organized repopulated host cells including a monolayer of endocardial endothelial cells, as well as scattered isolated islands of cardiomyocytes. Only foreign body reaction was seen in the Dacron patch, which was supported by the capillary density analysis (ECM: 27.9 ± 10.1/mm2, Dacron: 18.5± 5.2/mm2; p CMR: SENC showed contractility in the ECM patch area (peak longitudinal strain: -13.6 ± 1.7 %, vs self-controlled normal RV: -17.9 ± 1.6%). Perfusion revealed reasonably restored blood perfusion in the ECM (relative maximum upslope: 11.5 ± 1.1, vs self-controlled normal RV: 16.0 ± 2.2). ECV of the patch region was visualized and calculated, yielding 78 ± 14 % in the patch; whereas self-controlled ECV value was 27 ± 3 % in normal RV. Conclusions: The ECM patch demonstrated constructive repopulation of host cells and early signs of restoring regional myocardial function with positive contractility and blood perfusion. CMR using our protocol showed efficacy to assess the regional and biological myocardial function of a remodeled tissue engineered scaffold
SciDAC advances in beam dynamics simulation: From light sources to colliders

In this paper, we report on progress that has been made in beam dynamics simulation, from light sources to colliders, during the first year of the SciDAC-2 accelerator project 'Community Petascale Project for Accelerator Science and Simulation (ComPASS).' Several parallel computational tools for beam dynamics simulation are described. Also presented are number of applications in current and future accelerator facilities (e.g., LCLS, RHIC, Tevatron, LHC, and ELIC).
A model of the human operator using sensitivity function shaping

A new model of the human operator in a compensatory tracking task is developed using a sensitivity function shaping control synthesis formulation. Weighting filters are chosen to shape the sensitivity functions of the closed-loop operator-controlled feedback system based-upon established characteristics of manual operator systems. The weighting filters are used to represent the operator's objective of error minimization and the inherent limitation of the operator to affect control at very high frequency. The model parameters can be computed using either H-infinity or H/sub 2/ control solutions. The new model retains the simplicity of the well-known crossover model yet is readily adapted to multi-loop control tasks. Several examples are given to compare the response of the new model to experimental data.
Abstract 9381: Comparison of Clinical Characteristics and Adverse Outcomes in Pregnant Women with Cardiomyopathy Subtypes at the Time of Delivery in the US: 2006-2010

Introduction: Investigation of patient characteristics and outcomes in women with cardiomyopathy (CDM) at the time of delivery has been limited. The aim of this study was to determine the clinical characteristics and outcomes in women with peripartum (PCDM) and hypertrophic cardiomyopathy (HCDM), and the predictors for adverse clinical outcomes in pregnant women at the time of delivery. Methods and Results: The Healthcare Cost and Utilization Project’s National Inpatient Sample was screened for hospital admissions for delivery in pregnant women with CDM subtypes (peripartum, hypertrophic and all others) from 2006-2010. Clinical characteristics and maternal outcomes were identified in women with subtypes of CDM and without. The primary outcome of interest was major adverse clinical events (MACE), a composite of in-hospital death, acute myocardial infarction, heart failure, arrhythmia, cerebrovascular event, or embolic event. Our study population consisted of 2,078 patients with CDM and 4,438,439 patients without CDM. Of those with CDM, 52 (2.5%) had HCDM, 1039 (50.0%) had PCDM, and 987 (47.5%) were classified as other CDM (OCDM). PCDM cohort was more likely to be insured by Medicaid and the HCDM patients were more likely to deliver at a teaching hospital (p Conclusions: Peripartum CDM patients had the highest likelihood of MACE compared to hypertrophic and all other CDM subtypes.
Another view of nonholonomic mechanical control systems

In this paper we consider nonholonomic control systems on Riemannian manifolds. Such systems evolve on sub-bundles of tangent bundles, defined by the nonholonomic constraints. This paper promotes the view of such systems as the restriction to the nonholonomic sub-bundle of "Newton-law" type problems on the entire tangent bundle, defined by, in general, non-Riemannian connections. These connections should be related to specific geometric properties of the nonholonomic system. We define a particular class of connections based on special symmetry properties, and demonstrate the validity of the construction through three examples.
RADIOSENSITIVITY OF SEVERAL DEHYDROGENASES AND TRANSAMINASES DURING SPOROGENESIS OF BACILLUS SUBTILIS

Rowley, D. B. (Syracuse University, Syracuse, N.Y.), and H. R. Newcomb. Radiosensitivity of several dehydrogenases and transaminases during sporogenesis of Bacillus subtilis. J. Bacteriol. 87:701-709. 1964.-Cells of Bacillus subtilis grown in a chemically defined medium for 17 hr, subsequently washed, and transferred to a phosphate solution containing CaCl(2) sporulated in a reproducible pattern. The synthesis of dipicolinic acid essentially paralleled the appearance of thermoresistant cells. X-ray resistant cells appeared 2 to 3 hr before the appearance of thermoresistant cells and the formation of dipicolinic acid. Changes in enzyme activity of cells undergoing sporogenesis varied among the enzymes studied. The transaminases exhibited a marked decrease in activity during early sporogenesis, whereas the dehydrogenases exhibited maximal activity. The determination of enzyme radioresistance in extracts of sporulating cells indicated that the resistance of transaminases remained essentially unchanged, whereas the dehydrogenases exhibited a decreased resistance early in sporogenesis. Although both glutamic-pyruvic transaminase and glutamic-oxaloacetic transaminase (GOT) were demonstrated in vegetative cells, only the latter was detected in mature spores. The radioresistance of GOT in vegetative-cell extracts was two to three times greater than in spore extracts.
Unraveling Aircraft Impacts

Aircraft emissions are likely to alter atmospheric chemistry at cruise altitudes, but quantifying these effects has been difficult. Two recent aircraft campaigns are providing much-needed constraints on the atmospheric chemistry at the relevant altitudes, in a region where effects would be expected to be relatively large--above North America, Europe, and the North Atlantic flight corridor. On the basis of these field data, the global climate forcing of aircraft-induced ozone change is expected to be at the lower end of model estimates.
RELATIONSHIP OF SERUM AND URINARY PROTEINS IN NEOPLASTIC STATES: A PRELIMINARY SURVEY.

Twenty-four-hour urine specimens from patients with and without malignancies were concentrated by dialysis. The electrophoretic mobility of the urine protein components was compared with that of the respective serum proteins. Control values were similar to those established in the literature. Urinary protein concentrations found in malignant states were higher. Generally, there is a positive correlation between serum concentration of globulins and urinary excretion. It is not possible to prove in either controls or in patients bearing malignancies that the amount of urinary protein excreted depends upon molecular size.
Electronic Health Records: A Case Study of an Implementation

Since healthcare institutions have to manage efficiently many terabytes of data on their patients, they need tools that allow them to have an easy access to their data and that enable them to share their data with every specialist involved in the treatment of a patient. That’s why they increasingly adopt EMR and EHR systems. As they are quite recent systems, healthcare institutions usually lack of experience to implement these systems. The purpose of this paper is to do a case study on the implementation of an EHR system in a local healthcare institution, and then to analyze this case study to give directions so as to avoid some arising issues.
Multifocal Choroiditis with Panuveitis: Incidence of Ocular Complications and of Loss of Visual Acuity

Purpose To estimate the incidences of ocular complications and vision loss in patients with multifocal choroiditis with panuveitis (MFCPU) and to describe the association between therapy and the incidences thereof. Design Retrospective cohort study. Participants Sixty-six patients (122 eyes) with MFCPU evaluated from January 1984 through June 2005 at a single-center academic practice. Methods Demographic and clinical information on patients diagnosed with MFCPU was collected and entered into a computerized database for statistical analyses. Main Outcome Measures Development of ocular complications, including choroidal neovascularization, epiretinal membrane, and cystoid macular edema (CME), and loss of visual acuity (VA) to 20/50 or worse and to 20/200 or worse. Results Among affected eyes of patients with MFCPU, frequencies of VAs of 20/50 or worse and of 20/200 or worse at presentation were 55% and 38%, respectively. Choroidal neovascularization was observed in 22% of affected eyes at presentation and was the leading cause of poor VA at presentation. The incidence rates of vision loss to 20/50 or worse and to 20/200 or worse were 0.19/eye-year (EY) and 0.12/EY in affected eyes and 0.07/person-year (PY) and 0.04/PY in better-seeing eyes. Choroidal neovascularization was the most common cause of incident vision loss, with approximately 45% of incident vision loss attributed to new-onset or recurrent choroidal neovascularization. Presence of epiretinal membrane and CME also was associated with the development of vision loss during follow-up. When taken in combination, the incidence of any posterior pole complication was 0.13/EY in affected eyes. Use of immunosuppressive drug therapy (but not low-dose corticosteroid therapy) was associated with an 83% reduction in the risk of posterior pole complications ( P = 0.004) and with a 92% reduction in the risk of 20/200 or worse VA in affected eyes ( P = 0.05). Of the 6 eyes with recurrent choroidal neovascularization, only one recurrence was observed, in a patient receiving immunosuppressive drug therapy. Conclusions Treatment with immunosuppressive drugs may improve VA outcomes among patients with MFCPU by reducing the risk of sight-threatening posterior pole complications, including new-onset choroidal neovascularization and recurrent choroidal neovascularization among eyes with existing choroidal neovascularization.
Low-Intensity Amplitude Modulated Ultrasound Increases Osteoblastic Mineralization

The purpose of this study was to assess the effect of pulsed amplitude modulated ultrasound (pAMUS) on the level of mineralization in osteoblast cell in comparison to cells stimulated with low-intensity pulsed ultrasound (LIPUS). To make the ultrasound effects more enhanced and targeted at region of interest, this study uses a novel approach of applying pulsed amplitude modulated ultrasound to osteoblast cells. The pAMUS signal was generated using two signal generators. Pulsed signal was amplified through a power amplifier and drove two identical focused ultrasound probes, focusing at the same point in the culture dish. The effects of pAMUS were evaluated using a pAMUS signal of 45 kHz and 100 kHz with 20% duty cycle. The hydrophone verified the formation of a focal point at equal distances (16 mm) from the surface of both transducers. Intensity profile using computer controlled 2D scanner showed circular focal point with a diameter of approximately 10 mm. The effect of the signal was studied using MC3T3-E1 cells cultured in osteogenic medium at time points Day 7, 12 and 18. The cells were analyzed for ALP activity and calcium mineralization. The pAMUS significantly increased the ALP activity and matrix calcification in comparison with LIPUS stimulated cultures.
Roles of specific membrane lipid domains in EGF receptor activation and cell adhesion molecule stabilization in a developing olfactory system.

Background Reciprocal interactions between glial cells and olfactory receptor neurons (ORNs) cause ORN axons entering the brain to sort, to fasciculate into bundles destined for specific glomeruli, and to form stable protoglomeruli in the developing olfactory system of an experimentally advantageous animal species, the moth Manduca sexta. Epidermal growth factor receptors (EGFRs) and the cell adhesion molecules (IgCAMs) neuroglian and fasciclin II are known to be important players in these processes. Methodology/Principal Findings We report in situ and cell-culture studies that suggest a role for glycosphingolipid-rich membrane subdomains in neuron-glia interactions. Disruption of these subdomains by the use of methyl-β-cyclodextrin results in loss of EGFR activation, depletion of fasciclin II in ORN axons, and loss of neuroglian stabilization in the membrane. At the cellular level, disruption leads to aberrant ORN axon trajectories, small antennal lobes, abnormal arrays of olfactory glomerul, and loss of normal glial cell migration. Conclusions/Significance We propose that glycosphingolipid-rich membrane subdomains (possible membrane rafts or platforms) are essential for IgCAM-mediated EGFR activation and for anchoring of neuroglian to the cytoskeleton, both required for normal extension and sorting of ORN axons.
India VS. United States undergraduates' attitudes concerning child sexual abuse: The impact of survivor sex, survivor age, survivor response, respondent sex, and country of origin

Abstract Written descriptions of sexual interaction between an adult and a 15-year-old child were utilized to study the impact of survivor sex, perpetrator sex, survivor response and country of origin (India vs. United States) on attribution of blame, labeling of child sexual abuse, perception of realistic survivor behavior, and effect on the child. MANCOVA results of responses collected from 720 undergraduate students (360 = Indian students: 360 = U.S. students) indicated that country of origin was related to the respondent ratings for the five vignette items. Other interactions obtained were related to the sex of the respondent, perpetrator and survivor, or the response of the survivor. Results are discussed relative to generalizability of results, child sexual abuse in India, and the need for educational programs in child sexual abuse.
A fast direct finite element solver for large-scale 3-D electromagnetic analysis

A fast direct solver is developed for the vector finite element based analysis of general 3-D electromagnetic problems. In this solver, we fully take advantage of the sparsity in the original matrix of size N and the reduced fill-ins due to nested dissection ordering. We also organize the overall factorization into a sequence of partial factorizations of dense smaller matrices by the multifrontal algorithm. We then accelerate the computation of all the intermediate dense matrices by ℌ-matrix based fast arithmetic. The computational complexity of the proposed solver is theoretically analyzed and shown to be O(N) in both time and storage for problems with a relatively small electric size. The solver's controlled accuracy is also proved. Numerical experiments demonstrate that the proposed solver outperforms both the state-of-the-art multifrontal solver and the ℌ-based direct solver for 3-D electromagnetic analysis.
An application of the least-squares method to system parameters extraction from experimental data.

We explore the possibility and the limits of extracting the parameters of the model from simulated logistic and Henon time series. For the models considered, the least-squares approach provides accurate values of the recurrence order and polynomial degree along with the model parameters. We found that the number of data points increases the accuracy of the estimation only for noise-free data. With the white noise added to the data, the accuracy could not be improved above a certain threshold that is almost independent of the number of data points. The additive noise flattened the global minimum of the least-squares function such that above a noise threshold it is no longer possible to discern the optimum values of the recurrence order and/or polynomial degree.
Recovery of Information Lost by the Least Squares Estimation in Real-Time Network Environment

Feedback mechanism based algorithms are frequently used to solve network optimization problems. These schemes involve users and network exchanging information to achieve convergence towards an optimal solution. However, in implementation, these algorithms do not guarantee messages will be delivered to the destination, especially when network congestion occurs, which in turn often results in packet drops. This condition may lead to algorithm failing to converge. To prevent this, we propose least square (LS) estimation algorithm to recover the missing information when packets are dropped from the network. Our results from several scenarios demonstrate that LS estimation can provide the convergence for feedback mechanism based algorithm.
Direct cellobiose production from cellulose using sextuple beta-glucosidase gene deletion Neurospora crassa mutants

Abstract Direct cellobiose production from cellulose by a genetically modified fungus—Neurospora crassa, was explored in this study. A library of N. crassa sextuple beta-glucosidase (bgl) gene deletion strains was constructed. Various concentrations of cellobiose were detected in the culture broth of the N. crassa sextuple beta-glucosidase (bgl) gene deletion strains when grown on Avicel without exogenous cellulase addition. The sextuple bgl deletion strains expressing one of the three basally transcribed bgl genes are the best cellobiose producers. For most sextuple strains, the multiple bgl gene deletion has no negative effect on the production of other cellulases. The induction of major endoglucanases and exoglucanases on Avicel in most of the sextuple bgl deletions strains was as fast as or faster than that of the wild type, except for strain F4. The best cellobiose producing strain, F5, produced 7.7 g/L of cellobiose from 20 g/L of Avicel in four days and utilized the Avicel as fast as did the wild type (even in the presence of high cellobiose concentration). The cellobiose yield from cellulose was about 48.3%.