cssi/SciSciGPT-SciSciNet huggingface dataset:
Patient self-disclosure: A review of the research.

Research shows that whereas most patients disclose deeply personal experiences in therapy, a significant proportion conceal some significant information. Findings also indicate that there are several categories of nondisclosed information (secrets, things left unsaid, and client reactions); that patients tend to withhold immediately experienced negative reactions; that disliked characteristics of oneself and parents are among the most thoroughly discussed issues in therapy while sex, aggression, and personal failure are least discussed; that men and women disclose to the same extent and on similar topics; that shame inhibits disclosure of negative affect; that a strong therapeutic alliance, overall tendency to be disclosing, and time in therapy facilitate disclosure; and that the discrepancy between disclosure and patients' ratings of salience of disclosure is a more powerful predictor of outcome than disclosure alone.
Distributed-circuit-element description of guided-wave structures and cavities involving double-negative or single-negative media

Materials with negative real effective permittivity and permeability (also known as "double-negative (DNG)" media) may exhibit interesting features that lead to unconventional phenomena in guidance of electromagnetic waves. As one such class of problems, in some of our earlier works we studied the guided wave propagation in structures containing a layer of DNG material paired with a slab of conventional (i.e., "double-positive (DPS)") material. In particular, we showed that such a DNG-DPS bilayer has unusual properties as a guided-wave structure. For instance, a parallel-plate waveguide filled with a pair of parallel lossless DNG and DPS layers may support dominant TE and TM modes that can propagate even when the waveguide total thickness is electrically very small. In the present work, we underline the possibility to explain some of the unconventional EM characteristics of such paired DPS-DNG waveguides and cavities using the distributed-circuit-element approach with appropriate choice of elements. The negative nature of the real part of permittivity and/or permeability affects the choice of such distributed circuit elements, and in turn the overall circuit structure exhibits certain natural "resonances" that may not be present when conventional materials are employed in such waveguides or cavities. The "circuit-element" approach can also be applied to "single-negative (SNG)" layers, in which only one of the material parameters, not both, has negative real part. Here, we first present a brief overview of our work on modal analysis in waveguides and cavities with DNG or SNG layers, and we then present our results on their distributed-circuit-element modeling.
Sensorless speed estimation of PMSM using a hybrid method

A hybrid estimator which combined the advantages of sliding mode estimator and extended Kalman filter for sensorless control of PMSM was proposed. The algorithm is more effective than sliding mode estimator for a motor with a distorted back-emf distribution. The hybrid estimator established a three-order EKF, considering the high order harmonics components of back-emf as system and measurement noise. It is easier to tune the parameters for the order lowered EKF estimator than traditional EKF estimator. It has a good performance for PMSM with no sinusoidal back EMF distributing while sliding mode estimator has a worse capability. Compared with the sliding mode estimator, traditional EKF estimator and hybrid estimator, the advantages and disadvantages of the hybrid estimator are illustrated.
Complications of bronchoscopy: A concise synopsis

Flexible and rigid bronchoscopes are used in diagnosis, therapeutics, and palliation. While their use is widespread, effective, and generally safe; there are numerous potential complications that can occur. Mechanical complications of bronchoscopy are primarily related to airway manipulations or bleeding. Systemic complications arise from the procedure itself, medication administration (primarily sedation), or patient comorbidities. Attributable mortality rates remain low at < 0.1% for fiberoptic and rigid bronchoscopy. Here we review the complications (classified as mechanical or systemic) of both rigid and flexible bronchoscopy in hope of making practitioners who are operators of these tools, and those who consult others for interventions, aware of potential problems, and pitfalls in order to enhance patient safety and comfort.
Dynamical localization in microdisk lasers

We demonstrate the lasing action from a dynamically localized mode in a microdisk resonator with rough boundary. Although substantial boundary roughness and surface defects in our devices imply strong light scattering and destroy the regular whispering gallery modes, the destructive interference of the scattered light leads to the dynamical Anderson localization in the phase space of the system and the formation of a different type of high-Q modes. Using direct optical imaging of the lasing mode and theoretical calculations, we show that the lasing modes in our devices has dynamical localization origin. This behavior, although demonstrated here in GaAs-InAs microdisk laser, should be applicable to any lasers and sensors based on semiconductor or polymer materials.
Tracking Observations: Using Handhelds and Computers for Classroom Observation Logging

This paper presents the synergistic use of handheld computers and desktop computers as tools for grade school teachers to record observational data from their classrooms. The system uses handheld devices to tersely log events in situ, and allows later reflection and elaboration through annotation of the logged events on desktop computer. The terse, ephemeral capture of events coupled with post-hoc annotation has been novelly exploited to design a system that supports teachers' development as reflective practitioners and enables richer capture of grade school student behaviour and performance.
Effect of Sex and Race of the Observer and Model on Imitation Learning.

The effects of sex and race of observer and model characteristics, verbal, motor and total numbers of imitative responses, were investigated within a 2 × 2 × 2 × 2 × 3 × 4 repeated measures design ...
Laboratory diagnostic systems for Ebola and Marburg hemorrhagic fevers developed with recombinant proteins.

Ebola virus and Marburg virus (EBOV and MARV, respectively) of the family Filoviridae cause hemorrhagic fever with high mortality rates, sometimes reaching 50 to 90% of infected individuals, in humans and nonhuman primates ([10][1], [16][2], [47][3]). EBOV consists of four species, Zaire EBOV, Sudan
A subclass of myosin XI is associated with mitochondria, plastids, and the molecular chaperone subunit TCP‐1α in maize

The role and regulation of specific plant myosins in cyclosis is not well understood. In the present report, an affinity-purified antibody generated against a conserved tail region of some class XI plant myosin isoforms was used for biochemical and immunofluorescence studies of Zea mays. Myosin XI co-localized with plastids and mitochondria but not with nuclei, the Golgi apparatus, endoplasmic reticulum, or peroxisomes. This suggests that myosin XI is involved in the motility of specific organelles. Myosin XI was more than 50% co-localized with tailless complex polypeptide-1α (TCP-1α) in tissue sections of mature tissues located more than 1.0 mm from the apex, and the two proteins co-eluted from gel filtration and ion exchange columns. On Western blots, TCP-1α isoforms showed a developmental shift from the youngest 5.0 mm of the root to more mature regions that were more than 10.0 mm from the apex. This developmental shift coincided with a higher percentage of myosin XI /TCP-1α co-localization, and faster degradation of myosin XI by serine protease. Our results suggest that class XI plant myosin requires TCP-1α for regulating folding or providing protection against denaturation. Cell Motil. Cytoskeleton 57:218–232, 2004. © 2004 Wiley-Liss, Inc.
Antibodies to hepatocyte membrane antigens in chronic liver disease: detection by immunofluorescence after Bouin's fixation.

Using a modified indirect immunofluorescent (IF) technique in which cryostat tissue sections were fixed in Bouin’s solution for ten minutes prior to reaction with sera under test, we have looked for antibodies to the hepatocyte membrane (HMA) in the sera of patients with chronic active hepatitis (CAH) and primary biliary cirrhosis (PBC). Sampies were tested initially in parallel on unfixed and Bouin’sfixed rat composite blocks (kidney, stomach, liver) at a titer of 1: 100 and those found to be positive were diluted further and reexamined. Conventional unfixed sections of rat composite block showed no liver membrane immunofluorescence although antinuclear (ANA), mitochondrial (AMA), and smooth muscle antibodies (SMA) were detected as anticipated. By contrast, prior Bouin’s fixation abolished most of the fluorescence due to ANA, AMA and
Neurotransmitter Receptor Activation Triggers p27(Kip1 )And p21(CIP1) Accumulation and G1 Cell Cycle Arrest in Oligodendrocyte Progenitors

We examined the pathways that link neurotransmitter receptor activation and cell cycle arrest in oligodendrocyte progenitors. We had previously demonstrated that glutamate receptor activation inhibits oligodendrocyte progenitor proliferation and lineage progression. Here, using purified oligodendrocyte progenitors and cerebellar slice cultures, we show that norepinephrine and the beta-adrenergic receptor agonist isoproterenol also inhibited the proliferation, but in contrast to glutamate, isoproterenol stimulated progenitor lineage progression, as determined by O4 and O1 antibody staining. This antiproliferative effect was specifically attributable to a beta-adrenoceptor-mediated increase in cyclic adenosine monophosphate, since analogs of this cyclic nucleotide mimicked the effects of isoproterenol on oligodendrocyte progenitor proliferation, while alpha-adrenoceptor agonists were ineffective. Despite the opposite effects on lineage progression, both isoproterenol and the glutamate receptor agonist kainate caused accumulation of the cyclin-dependent kinase inhibitors p27(Kip1)and p21(CIP1), and G1 arrest. Studies with oligodendrocyte progenitor cells from INK4a−/− mice indicated that the G1 cyclin kinase inhibitor p16(INK4a) as well as p19(ARF)were not required for agonist-stimulated proliferation arrest. Our results demonstrate that beta-adrenergic and glutamatergic receptor activation inhibit oligodendrocyte progenitor proliferation through a mechanism that may involve p27(Kip1) and p21(CIP1); but while neurotransmitter-induced accumulation of p27(Kip1) is associated with cell cycle arrest, it does not by itself promote oligodendrocyte progenitor differentiation.
A measure of fault-tolerance for distributed networks

The authors consider probabilistic networks having links that are perfectly reliable but nodes that fail randomly and independently with known probabilities. They define a fault-tolerance measure of such network that is directly affected by the choice of its underlying graph and the location of its node-components. A state of the network is tolerant if the currently operating nodes comprise a connected subnetwork. The probability of the network being in a tolerant state is the fault-tolerance (FT) measure of the network. The authors are concerned with the design of globally-best tolerant networks, that maximize FT for any given set of node-operating probabilities. They study this measure of fault-tolerance by developing combinatorial tools and by determining the optimal networks in both 'sparse' and 'dense' classes. >
Mice with the testicular feminization mutation demonstrate a role for androgen receptors in the regulation of anxiety-related behaviors and the hypothalamic–pituitary–adrenal axis

Testosterone (T) appears to play a role in anxiety and sensorimotor gating in rodents, but whether T acts through the androgen receptor (AR) to influence these behaviors is less clear. We compared adult genetic male mice with the testicular feminization mutation (Tfm), which lack functional ARs, to wild type male littermates (wt males) on an assay of sensorimotor gating (prepulse inhibition of the acoustic startle response; PPI) and several tests thought to reflect anxiety: open field exposure, novel object exposure, elevated plus maze (EPM), and light/dark (LD) box. PPI was similar between groups, but indices of anxiety in the novel object and LD box tests were increased in Tfm males with no significant differences found in the open field or EPM. Since Tfm male mice have decreased circulating T, the same tests were conducted in mice that were gonadectomized (wt males) or sham-operated (Tfm males) as adults and supplemented with T or nothing (B). While T treatment reduced indices of anxiety in the novel object and LD box tests in wt males, it was ineffective in Tfm males. Increased indices of anxiety in Tfm males appear to be related to hyper-activation of the hypothalamic-pituitary-adrenal axis since levels of the stress hormone corticosterone were elevated in Tfm males compared to wt males at baseline and at several time points after exposure to a novel object. These findings demonstrate that ARs influence anxiety and stress responses in mice.
Abnormalities of leukocyte chemotaxis in patients with various forms of periodontitis.

Prior studies have documented that a majority of patients with juvenile periodontitis have suppressed polymorphonuclear leukocyte (PMN) chemotaxis. However, in other forms of earlyonset periodontitis, PMN migration has been studied only to a limited extent or not at all, and monocyte (MN) chemotaxis has not been extensively studied in patients with any of the forms of periodontitis. Accordingly, PMN and MN chemotaxis was studied in 7 patients with prepubertal, 37 with juvenile, and 35 with rapidly progressive periodontitis. In addition, PMN chemotaxis was studied in 8 patients with adult periodontitis. In the prepubertal group, 5 patients had abnormal PMN chemotaxis, 5 had depressed MN chemotaxis, and one had reduced serum chemotactic activity. All patients in this group had at least one form of leukocyte chemotaxis abnormality. In the juvenile periodontitis group, 17 patients had abnormal PMN responses, 16 of these were depressed while 1 was enhanced. MN chemotaxis was depressed in 4 of these patients and elevated in 2. Five patients had reduced serum chemotactic activity and one manifested a serum chemotactic inhibitor. In total, 65% of juvenile patients had some form of abnormality. In the rapidly progressive group, 15 had abnormal PMN chemotaxis, 7 had aberrant MN chemotaxis, 4 had reduced serum chemotactic activity, and 8 had a serum inhibitor of chemotaxis. No abnormalities were found in the PMNs or sera of patients with adult periodontitis. Overall, 66% of the early-onset patients manifested some form of cell or serum-related leukocyte chemotactic abnormality. Thus, abnormalities of leukocyte chemotaxis were present in all patients with prepubertal periodontitis and in a majority of those with juvenile and rapidly progressive disease, while no abnormalities were found in 8 patients with adult periodontitis.
Event-Related Potentials, Emotion, and Emotion Regulation: An Integrative Review

Progress in the study of emotion and emotion regulation has increasingly been informed by neuroscientific methods. This article focuses on two components of the event-related potential (ERP)--the P300 and the late positive potential (LPP)--and how they can be used to understand the interaction between the more automatic and controlled processing of emotional stimuli. Research is reviewed exploring: the dynamics of emotional response as indexed at early and late latencies; neurobiological correlates of emotional response; individual and developmental differences; ways in which the LPP can be utilized as a measure of emotion regulation. Future directions for the application of ERP/electroencephalogram (EEG) in achieving a more complete understanding of emotional processing and its regulation are presented.
The effect of sodium pentobarbital on attraction in the albino rat

Two “target” rats, one drugged and one undrugged, were tethered on opposite sides of an open arena in which single, undrugged “subject” rats were allowed to roam free. On the last 2 days of testing, the S rats spent significantly more time in physical contact with the undrugged target rat than with the drugged target rat. Prior adaptation to the arena of S rats had no effect on the relative preferences for the target animals.
GFP-FRNK Disrupts Focal Adhesions and Induces Anoikis in Neonatal Rat Ventricular Myocytes

Focal adhesion kinase (FAK) is a nonreceptor protein tyrosine kinase involved in adhesion-dependent signal transduction. FAK is highly expressed in cultured neonatal rat ventricular myocytes (NRVMs) and undergoes tyrosine autophosphorylation in response to cell adhesion, stretch, and growth factor stimulation. We previously showed that inhibition of FAK phosphorylation by adenovirally mediated overexpression of FRNK (the autonomously expressed C-terminal domain of FAK) prevented endothelin-1 (ET)-induced NRVM hypertrophy. One question raised by these studies was whether FRNK localized to focal adhesions and displaced FAK from sites required for downstream signaling. Therefore, we constructed a replication-defective adenovirus encoding a GFP-FRNK fusion protein (Adv-GFP-FRNK) and examined its effects on NRVM cytoarchitecture and signaling. Uninfected NRVMs contained small amounts of endogenous FRNK. NRVMs infected with Adv-GFP-FRNK expressed much larger amounts of a 66-/68-kDa protein that localized to costameres and focal adhesions. GFP-FRNK overexpression suppressed basal and ET-induced FAK phosphorylation and also inhibited ET-induced phosphorylation of PYK2, the other member of the FAK family of nonreceptor protein tyrosine kinases. In contrast, GFP-FRNK overexpression did not prevent ET-induced ERK, JNK, or p70S6K phosphorylation. Furthermore, GFP-FRNK resulted in the loss of detectable FAK and paxillin in focal adhesions, which was accompanied by reduced levels of total paxillin and, ultimately, cell detachment and apoptosis. We conclude that FRNK functions as a dominant-negative inhibitor of adhesion-dependent signaling by displacing FAK from focal adhesions and interfering with the anchorage of NRVMs that is necessary for cell survival, a process known as anoikis.
Mutation at Residue 523 Creates a Second Receptor Binding Site on Human Parainfluenza Virus Type 1 Hemagglutinin-Neuraminidase Protein

The paramyxovirus hemagglutinin-neuraminidase (HN) is a multifunctional protein mediating hemagglutination (HA), neuraminidase (NA), and fusion promotion activities. It has been a matter of debate whether HN contains combined or separate sites for HA and NA activities. To clear the issue, we determined the presence of the second binding site on human parainfluenza virus (hPIV) type 1, 2, and 3 and Sendai virus (SeV) HN proteins. Results of virus elution from erythrocytes at an elevated temperature and HA inhibition by NA inhibitor BCX-2798 suggest that all hPIVs bind to the receptor only through the NA catalytic site, while SeV HN has an additional receptor binding site. Comparison of SeV and hPIV1 HN sequences revealed two amino acid differences at residues 521 and 523 in the region close to the second binding site identified in Newcastle disease virus HN. We mutated hPIV1 HN at position 523 from Asn to the residue of SeV HN, Asp, and rescued a recombinant SeV that carries the mutated hPIV1 HN by a reverse genetics system. The hPIV1 HN with Asp at position 523 hemagglutinated in the presence of BCX-2798, suggesting that the amino acid difference at position 523 is critical for the formation of a second binding site. Creation of the second binding site on hPIV1 HN, however, did not significantly affect the growth or fusion activity of the recombinant virus. Our study indicates that the presence and requirement of a second binding site vary among paramyxoviruses.
“Handles to Hang on to Our Sobriety” Commonplace Books and Surrendered Masculinity in Alcoholics Anonymous

Commonplace books—collections of edifying prose and poetry—have been recognized as an important tool of self-fashioning from the early modern period onward. This article examines the practice of commonplace making by men in the fellowship of Alcoholics Anonymous, where the form becomes a unique expression of the “surrendered masculinity” on which recovery from addiction hinges. The author argues that the embrace of this nontraditional gender identity by the predominately White male population of AA suggests that the category of hegemonic masculinity may be destabilized by men’s spiritual investments.
Chapter 10 Chemical and spectroscopic studies of ultrathin oxide films

Publisher Summary The surfaces of metal oxides are important chemically active catalysts, chemical sensors, corrosion inhibitors, ceramics, and electronic and dielectric materials. One way to circumvent these problems is the use of surface science techniques employing surface sensitive charge particle probes under the requisite ultra-high vacuum (UHV) conditions. This approach to studying oxide surfaces has a particularly difficult set of problems in that many of the metal oxides are wide band gap semiconductors or insulators with poor electronic and thermal conductivities. The use of electron- or ion-based spectroscopies induces a charging problem limiting the effectiveness of these probes on bulk (or even powder) oxide surfaces. A related problem is the imaging of oxide surfaces with scanning tunneling microscopy (STM) because this requires the flow of current between the probe tip and a conducting medium. Recent work in the laboratory has used STM imaging to investigate the morphology of the ultrathin metal oxides and metal particles supported on the ultrathin oxide films.
The Marian Dimension to the First Executions of the Reformation

This article investigates the Marian dimension to the Reformation’s first executions, the burning of the Augustinian friars Heinrich Voes and Johann van den Esschen in Brussels on July 1, 1523. Using sources generated by their case, it argues that the Reformation debate over how Christians should understand the Virgin Mary became interwoven with their case, and more specifically that their deaths were utilized by the ecclesiastical authorities (both Catholic and pro-Reformation) as a platform to debate Mary’s powers and efficacy. It further reveals the surreptitious nature of ways in which Catholic forces integrated beliefs surrounding the Virgin Mary into their explanation of events of the case, and the equally cunning strategy of their opponents to respond to such implications in implicit rather than overt ways. The result is a more textured and nuanced understanding of the meaning, methods, and utility of the conflict over Marian piety in the early Reformation.
Is Authority in Public Administration Separable from Authoritarianism? Personalities, Institutions, and Resistance

This paper explores the relationship between authority and authori tarianism, and the significance of this relationship to public adminis trators and their practice. I argue that authority and authoritarianism are not distinct, and that public administrators should rethink the value of authority as a justification for action. I explore two sources of authority/authoritarianism, personality and institutions, through the works of George Orwell, Theodor Adorno et al. (1950), and Michel Foucault. Though I do not posit a root cause of authority/ authoritarianism, I suggest ways that public administrators can re duce their reliance on authority as a justification through self-aware ness and the resistance of the institutional roles that they take on. In conclusion, I link the resistance of political authority to theories that undermine epistemological authority.
Keeping intruders at large: A graph-theoretic approach to reducing the probability of successful network intrusions

It is well known that not all intrusions can be prevented and additional lines of defense are needed to deal with intruders. However, most current approaches use honeynets relying on the assumption that simply attracting intruders into honeypots would thwart the attack. In this paper, we propose a different and more realistic approach, which aims at delaying intrusions, so as to control the probability that an intruder will reach a certain goal within a specified amount of time. Our method relies on analyzing a graphical representation of the computer network's logical layout and an associated probabilistic model of the adversary's behavior. We then artificially modify this representation by adding “distraction clusters” — collections of interconnected virtual machines — at key points of the network in order to increase complexity for the intruders and delay the intrusion. We study this problem formally, showing it to be NP-hard and then provide an approximation algorithm that exhibits several useful properties. Finally, we present experimental results obtained on a prototypal implementation of the proposed framework.
Spoken Through Desire: Maternal Subjectivity and Assisted Reproduction

This article addresses maternal subjectivity in relation to assisted reproductive technology (ART) and infertility. Although ART is used widely, discourse surrounding this technology remains largely unarticulated in psychoanalytic writing, a silence that may reflect a collective struggle to process its meanings. Engaging the work of Lacan and his emphasis on subversion and desire, I discuss my work with Nora, a woman who undergoes ART for 8 years, and explore the loss and abjection she faces surrounding infertility and ART's repeated failures. I argue that a technology dialogic around reproduction produces an illusion of control and an implicit promise of success that latches onto the notion of motherhood as the idealization of femininity. Reflecting on ART in a cultural and intergenerational context, I explore ART's discourse for both its creative, nonnormative potentials as well as for reproducing constricting, social practices.
Effects of substance P on Na and K transport in perfused main submandibular duct of rat.

AbstractSubstance P (2 and 4 μg/kg · min, iv) caused an inhibition of net efflux of Na and net influx of K in perfused main excretory duct of rat submandibular gland. These effects could not be blocked by atropine sulfate. The data suggest that substance P receptors are present in the duct cells and play a role in the regulation of transductal electrolyte transport.
Application of Video Monitoring System in Power System

With further development of image processing and computer visual technology,intelligent video safety monitoring technology is gradually used for more applications including in detection for specific abnormalities of power system such as detection for human bodies in restricted and dangerous areas,analysis on human body walking or electric shock and falling.According to core requirements for safety and stability of power system,this paper designs and proposes a set of realtime intelligent video monitoring system which is able to automatically analyze video contents and abnormal events in detecting scenes.Experiment result indicates that this system is provides with real-time processing ability which is able to realize successful detection rate of 96% and 93% respectively concerning with human body detection and simulating electric shock and falling.
[Chromatin structure, heterochromatin, and transposable genetic elements--are they from one team?].

Gene content proved to be less than expected in completely sequenced eukaryotic genomes. Moreover, gene number differs only three times between such distant organisms as human and Drosophila. Hence it is likely that the essential functional and structural differences between the two species mostly depend on the regulation of gene activity than on the set and quality of genes themselves. New data demonstrate that changes in chromatin structure play a greater role in the fine gene activity regulation than considered before. R.B. Khesin had foresaw many chromatin functions that only recently came to be recognized. Khesin was interested in genome inconstancy over his last years. A higher content of several important chromosomal proteins was recently revealed in chromatin of transposable genetic elements (TGE). The possible role of TGE in chromatin organization in the nucleus is considered.
Identification of Potentially Pathogenic Variants in the Posterior Polymorphous Corneal Dystrophy 1 Locus

Posterior polymorphous corneal dystrophy 1 (PPCD1) is a genetic disorder that affects corneal endothelial cell function and leads to loss of visual acuity. PPCD1 has been linked to a locus on chromosome 20 in multiple families; however, Sanger sequencing of protein-coding genes in the consensus region failed to identify any causative missense mutations. In this study, custom capture probes were utilized for targeted next-generation sequencing of the linked region in a previously reported family with PPCD1. Variants were detected through two bioinformatics pipelines and filtered according to multiple criteria. Additionally, a high-resolution microarray was used to detect copy number variations. No non-synonymous variants in the protein-coding region of annotated genes were identified. However, 12 single nucleotide variants in 10 genes, and 9 indels in 7 genes met the filtering criteria and were considered candidate variants for PPCD1. Eleven single nucleotide variants were confirmed by Sanger sequencing, including 2 synonymous variants and 9 non-coding variants, in 9 genes. One microdeletion was detected in an intron of OVOL2 by microarray but was subsequently not identified by PCR. Using a comprehensive next-generation sequencing approach, a total of 16 genes containing single nucleotide variants or indels that segregated with the affected phenotype in an affected family previously mapped to the PPCD1 locus were identified. Screening of these candidate genes in other families previously mapped to the PPCD1 locus will likely result in the identification of the genetic basis of PPCD1.
Dilatancy and spatial distribution of aftershocks

The pre-earthquake dilatancy, postulated to explain certain premonitory seismic velocity changes, may provide a preferred direction of groundwater flow persisting after the occurrence of a shallow earthquake. This direction is parallel to and nearly coincident with the compressive stress axis associated with the focal mechanism of the principal shock. Aftershocks may result from a redistribution of pore pressure and fluid flow not only along faults but also along this direction of relatively large permeability. This suggestion provides a possible explanation for certain observations of aftershocks aligned along the compressive stress direction.
L-Bench: An Android benchmark set for low-power mobile GPUs

Abstract In recent years GPUs have become one of the most important components in mobile application processors (APs). Thus, performance measurement and analysis of mobile GPUs are crucial to mobile AP manufacturers, device manufacturers, graphics application programmers, and end users. However, it is hard to analyze mobile GPUs in depth via existing high-level (with frames per second) or low-level benchmarks (with a fill rate, ALU performance, etc.). To bridge the gap between the benchmarks, we present a novel Android benchmark set for low-power GPUs, called L-Bench. This benchmark set consists of mid-level micro-benchmarks implemented on OpenGL ES 3.1, which are carefully chosen for different workloads. By analyzing the results, this benchmark suite provides not only frames per second of each benchmark but also performance of each GPU subsystem (geometry units, ALUs, texture mapping units, raster operations pipelines, caches/memory units, and tessellators) and overall GPU performance. For experiments, we perform our benchmark suite on five representative mobile devices that have different mobile GPUs, after that, we describe comprehensive analysis of each GPU architecture.
Bluetooth Security in Wearable Computing Applications

Advances in wireless sensor networking technologies have been extended to wearable computing systems and opened a plethora of applications and opportunities in the development and integration of pervasive Bluetooth Technologies with the abundance of existing specialized technologies in monitoring, data collection, and real-time analysis and reporting. Although the Bluetooth framework is acceptably secure, there are still a number of weaknesses in the Bluetooth technology. The nature of the wireless ad hoc and the device addressing schemes still make the Bluetooth protocol vulnerable to possible attacks and risks. This paper analyzes some of the vulnerabilities of Bluetooth architecture to possible attacks and risks and the best practices and countermeasures needed to thwart these attacks that target Bluetooth devices and their attached networks. It concentrates on Bluetooth technology security issues and challenges that face wireless computing systems.
The impact of multiple immersion levels on data quality and panelist engagement for the evaluation of cookies under a preparation-based scenario

Abstract Prior research indicates using immersive technologies to restore relevant contextual cues during product acceptance testing leads to more discriminating and reliable data likely due to improved ecological validity and heightened panelist engagement. However, as the use of immersive technologies in food and consumer product testing is emerging, the opportunities and limitations associated with such paradigms remain largely unexplored. To gain further insight, panelists assessed cookie liking in a traditional testing environment devoid of contextual information and two immersive environments in which audiovisual and olfactory cues depicting the baking of cookies in a home kitchen were presented. In the mixed immersion condition contextual information was presented to panelists via computer screen, head phones and localized aroma dispersion while evaluating cookies in a sensory booth. In the full immersion condition, the same information was presented via video wall, surround sound ceiling speakers and hidden scent dispersal. Following a three-week hiatus, panelists re-assessed the same cookies in the same three conditions. Despite panelists indicating similar levels of engagement in the two immersive conditions, hedonic data proved to be more discriminating and reliable in the fully immersive environment. These data indicate that scenarios depicting food preparation provide relevant contextual information that can influence product liking. Moreover, as the level of immersion becomes more complete, the discriminability and reliability of consumer acceptance data improves. Whether similar findings are observed with other product-scenario combinations remains to be explored.
Strong Electron–Phonon Coupling and Self-Trapped Excitons in the Defect Halide Perovskites A3M2I9 (A = Cs, Rb; M = Bi, Sb)

The optical and electronic properties of Bridgman grown single crystals of the wide-bandgap semiconducting defect halide perovskites A3M2I9 (A = Cs, Rb; M = Bi, Sb) have been investigated. Intense Raman scattering was observed at room temperature for each compound, indicating high polarizability and strong electron–phonon coupling. Both low-temperature and room-temperature photoluminescence (PL) were measured for each compound. Cs3Sb2I9 and Rb3Sb2I9 have broad PL emission bands between 1.75 and 2.05 eV with peaks at 1.96 and 1.92 eV, respectively. The Cs3Bi2I9 PL spectra showed broad emission consisting of several overlapping bands in the 1.65–2.2 eV range. Evidence of strong electron–phonon coupling comparable to that of the alkali halides was observed in phonon broadening of the PL emission. Effective phonon energies obtained from temperature-dependent PL measurements were in agreement with the Raman peak energies. A model is proposed whereby electron–phonon interactions in Cs3Sb2I9, Rb3Sb2I9, and Cs3Bi...
The maturing of adaptive control

The following paper is a brief history of adaptive control theory during the period 1955-1990
Distracted Walking, Bicycling, and Driving: Systematic Review and Meta-Analysis of Mobile Technology and Youth Crash Risk

This article examined the impact of mobile technology on young pedestrians, bicyclists, and drivers. A systematic search yielded 41 articles meeting inclusion criteria: peer-reviewed, published before February 1, 2016, behavioral outcome related to pedestrian, bicycling, or driving in the presence of mobile technology use, youth sample. Eleven studies were meta-analyzed to evaluate increased risk for crash/near-crash while distracted. Risk of bias and quality of research were assessed. Across methodologies, developmental stages, and type of distracting task, mobile technology use impairs youth safety on the road. Quality of evidence was low (pedestrian) to moderate (driving). Findings are discussed from the perspective of cognitive and visual distractions. Policy and behavioral efforts should continue to reduce mobile technology use in transportation settings.
Sustainable Hacking: Characteristics of the Design and Adoption of Civic Hacking Projects

Public organizations increasingly collaborate with civic-minded technologists to develop digital interventions for public issues through civic hacking projects. However, civic hacking cannot be a long-term solution without a proper handover and sustainability plan. In this study, we investigated how to design sustainable civic hacking projects for local governments and nonprofit organizations through intentional planning during the design process. We examined the design process of 16 civic hacking projects in a small Midwestern city in the United States. Drawing on observations, interviews, and documentation analysis, we argue that sustainable hacking should leverage off-the-shelf technologies and build good relationships with various stakeholders. Partners and technologists should also learn from each other about community practices and how to develop a data mindset. We discuss the design and practical implications to facilitate more sustainable civic hacking design processes for public organizations.
Robust Approximate Stochastic Modeling and Partial Realization

Abstract Algorithms for partial realization, which try to exactly match given stochastic information, are very sensitive to disturbances in that information sequence. These disturbances may arise due to finite wordlength computations, but more often they are inherent in the information itself; for example when the latter is a subset of estimated covariances. Under such practical circumstances there often is no underlying high order model that matches the information, and most algorithms fail. We investigate robust approaches to approximately realizing or modeling a stochastic information sequence, which then finds application in robust realization, robust stochastic modeling, and in robust reduced order stochastic modeling The approaches covered are covariance sequence modal decomposition, information sequence windowing followed by exact realization, iterative projection approximation, and gradient-based algorithms. These are contrasted in terms of properties, problems, and performance
Pose estimation of autonomous vehicles using visual information: A minimum-energy estimator approach

Abstract This paper addresses the pose estimation problem for autonomous vehicles that use a monocular charged-coupled-device (CCD) camera mounted onboard that observes the apparent motion of stationary points. We formulate the problem in the framework of state estimation of a state-affine system with multiple perspective outputs. Resorting todynamic programming, we derive a minimum-energy estimator which produces an estimate of the state that is “mostcompatible” with the dynamics, in the sense that it requires the least amount of noise energy to explain the measured outputs. In our formulation we take directly into account that the measurements arrive at discrete-time instants, are time-delayed, and may not be complete. In this way, we can deal with usual problems in vision systems such as noise as well as latency and intermittency of observations. The convergence of the proposed observersystem is analyzed and simulations results are presented and discussed.
Aptitude measures in SLA: Aptitude and achievement measures as predictors of growth in second language proficiency

The present study examines a US Department of Defense (DOD) foreign language program using linear and logistic regression to model foreign language proficiency growth over three time intervals. The analysis demonstrates growth from start to finish for a program involving domestic immersion and study abroad and tests the ability of aptitude and achievement measures to predict that growth for a group of 80 students. The findings suggest that a measure of foreign language aptitude and a measure of quantitative aptitude differentiate learning outcomes for the intensive domestic immersion portion of the program while measures of quantitative aptitude and native language verbal aptitude differentiate later-stage learners on the study abroad portion of the program.
Estimation of the year-on-year volatility and the unpredictability of the United States energy system

Long-term projections of energy consumption, supply and prices heavily influence decisions regarding long-lived energy infrastructure. Predicting the evolution of these quantities over multiple years to decades is a difficult task. Here, we estimate year-on-year volatility and unpredictability over multi-decade time frames for many quantities in the US energy system using historical projections. We determine the distribution over time of the most extreme projection errors (unpredictability) from 1985 to 2014, and the largest year-over-year changes (volatility) in the quantities themselves from 1949 to 2014. Our results show that both volatility and unpredictability have increased in the past decade, compared to the three and two decades before it. These findings may be useful for energy decision-makers to consider as they invest in and regulate long-lived energy infrastructure in a deeply uncertain world.
A review of acoustic research in physical educational settings

This presentation will review past and current acoustic research in physical education settings. Research suggests that the acoustic issues in physical education settings are likely detrimental to student learning (Ryan, 2009a; Ryan, Grube, & Mokgwati, 2010; Ryan & Mendell, 2010). The problem is compounded if there are students with special needs including learning disabilities, attention and auditory disorders, and students who are listening and learning in a non-native language. In addition, typical classroom teachers are faced with many voice concerns; however, physical education teachers are faced with poor acoustically designed gymnasiums, covered areas, and loud outdoor teaching environments which are more challenging than a typical indoor classroom (Ryan, 2009a). Ryan (2010) viewed physical education settings as “hostile listening environments” and have the potential to effect student learning and damaging teacher’s voices.
"Now you're competing": how historically-Black colleges and universities compete (and don't) on the Internet

No extant research has examined the web presence, web popularity, and paid adword tactics of historically-Black colleges and universities (HBCUs) compared to similar institutions. This study explores these measures and evaluates how HBCU web presence, web popularity, and paid search tactics compare to similar institutions to learn whether HBCUs are competing in one of the most competitive global higher education markets: the Internet. Findings suggest HBCU websites are smaller and less popular, and HBCUs spend less on web advertising than non-HBCU peers. Additionally, non-HBCUs are 3.8 times more likely to purchase desktop adwords and 4.3 times more likely to purchase mobile adwords than HBCUs. HBCUs need to harness the power of this global market to compete in a globalized, twenty-first century higher education market. If not, the financial situations between HBCUs could exacerbate, potentially threatening the livelihood of some of the most successful and time-honored institutions in the United States.
The cell type-specific octamer transcription factor OTF-2 has two domains required for the activation of transcription.

Abstract Many studies indicate that the cell type-specific transcription factor OTF-2 plays a central role in the lymphoid-specific transcription of immunoglobulin genes. In order to better understand the mechanisms regulating transcriptional selectivity, we have initiated a functional dissection of OTF-2. By mutagenesis of an OTF-2 cDNA and by subsequent transfection into non-lymphoid cells we have defined two domains that are required jointly for high levels of transcription from a lymphoid-specific target promoter. One of these domains, located at the extreme carboxy-terminus, is rich in proline. The other domain, which appears to represent a novel type, is located upstream of the POU-specific box and contains clusters of intermingled proline, glutamine and leucine residues. Point mutations that change either groups of glutamine or groups of leucine show that both types of amino acids are required for function. Our data indicate that a high content in a particular amino acid does not necessarily suffice to generate a potent activation domain but that severe structural constraints may also play a major role.
Diffusion-Controlled Delivery of Proteins from Hydrogels and Other Hydrophilic Systems

The short in vivo half-life of many pharmaceutically active proteins necessitates the need for multiple administrations to produce a therapeutic response, emphasizing the applicability of controlled release formulations (Lee, 1992). The key variables that affect protein transport through hydrophilic polymers depend on the delivery mechanism and device properties, in a similar manner as in the case of lower-molecular-weight drug substances. However, in the case of proteins, the role of solute molecular size is much more dramatic in hindering the diffusion and release from hydrophilic polymers (am Ende, 1993). Another critical consideration in protein delivery from hydrogel systems is the potential for protein denaturation in the device. For diffusion-controlled delivery systems, where water is the main transporting medium, the protein solution stability governs the type of device. Extended releasing times can be achieved with reservoir systems (Fig. 1) for highly stable proteins (Langer, 1990). Alternatively, dehydrated delivery systems
Food Insecurity: How You Can Help Your Patients

Physicians can improve the health of patients who experience food insecurity by following the SEARCH (screen, educate, adjust, recognize, connect, help) mnemonic and by using the resources outlined in this article.
Pinnacle polyethylene liner dissociation: a report of 3 cases

Abstract We describe 3 cases of DePuy Pinnacle polyethylene dissociations, their presentations, and treatment. A 34-year-old female with arthritis secondary to dysplasia, a 51-year-old male with avascular necrosis of the femoral head, and a 57-year-old female with osteoarthritis were treated with total hip arthroplasty. Acute nontraumatic polyethylene liner dissociations occurred at 31, 42, and 2 months postoperatively. They were treated with component retention and modular femoral head and liner revision. The 51-year-old male subsequently developed a prosthetic joint infection requiring explant of his components. Although dissociation of polyethylene liners from the DePuy Pinnacle acetabular components is an uncommon complication, this problem may increase in prevalence with longer term follow-up, and vigilance is recommended.
Long-term outcomes of high-dose melphalan and carmustine followed by autologous hematopoietic cell transplantation for multiple myeloma.

8026Background: Autologous hematopoietic cell transplantation (AHCT) is an important component of multiple myeloma treatment. Single-agent melphalan is the most commonly used conditioning regimen. ...