cssi/SciSciGPT-SciSciNet huggingface dataset:
A contemporary compendium of literature on the oncology advanced practice nurse role (2005–2012)

Improving neuro-oncological patients care: basic and practical concepts for nurse specialists in neuro-rehabilitation. BARTOLO M, ZUCCHELLA C, PACE A, DE NUNZIO AM, SERRAO M, SANDRINI G, PIERELLI F. Journal of Experimental & Clinical Cancer Research 2012;31(1):82, http://dx.doi.org/10.1186/1756-9966-31-82 The critical role of oncology nurse practitioners in cancer care: future implications. BISHOP CS. Oncology Nursing Forum 2009;36(3):267e269 Cancer patients’ perceptions of the oncology nurse practitioner role in cancermanagement: future implications (Abstract 4060). BISHOP C. Oncology Nursing Forum 2009;36(6):E346 Areyouamid-level provider, a physician extender, or a nurse? (Editorial). BOYLE D. Oncology Nursing Forum 2011;38(5):497 Role of advanced nurse practitioners and physician assistants in Washington state. BRITELL JC. Journal of Oncology Practice 2010;6(1):37e38 Managing the growth of a transplant center with regards to nurse practitioner staffing (Abstract 4056). BROM H. Oncology Nursing Forum 2009;36(6):E346 Evaluating health-related quality of life and priority health problems in patients with prostate cancer: a strategy for defining the role of the advanced practice nurse. BRYANTLUKOSIUS D, BROWNE G, DICENSO A, WHELAN T, GAFNI A, et al. Canadian Journal of Oncology Nursing 2010;20(1):5e14 A survey of oncology advanced practice nurses in Ontario: profile and predictors of job satisfaction. BRYANT-LUKOSIUS D, GREEN E, FITCH M, MACARTNEY G, ROBB-BLENDERMAN L, et al. Nursing Leadership (Tor Ont) 2007;20(2):50e68 Advanced practice nursing in radiation oncology. CARPER E, HAAS M. Seminars in Oncology Nursing 2006;22(4):203e211 From unit based to population focused: transforming the role of oncology clinical nurse specialists. CATANIA K, TALETHA A, BIRKHIMER D, COURTNEY C, HANES D, et al. Clinical Nurse Specialist 2012;26(2):103e106 Embracing technology: patients’, family members’ and nurse specialists’ experience of communicating using e-mail. CORNWALL A, MOORE S, PLANT H. European Journal of Oncology Nursing 2008;12(3):198e208 Clinical practice guideline use by oncology advanced practice nurses. CUNNINGHAMRS. Applied Nursing Research 2006;19(3):126e 133 The ASCO study of collaborative practice arrangements: a nurse practitioner’s point of view. DEVINE H. Journal of the Advanced Practitioner in Oncology 2012;3(1):47e48
Cognition and survey measurement: History and overview

In 1978 a small group of cognitive psychologists and survey methodologists initiated research in a new and exciting interdisciplinary field. This research applies the methods and theories of cognitive science to the study of respondents' answers to autobiographical and attitude surveys. This article describes the events that led up to the initiation of research, describes the history of the field, and overviews the cutting edge of research. Finally, the article offers perspectives on the benefits of collaborative research to both cognitive science and survey research, and the prospects for future research.
Completeness of Sets of Delayed-Logic Devices

This paper concerns a property of sets of delayed-logic devices. This property, called completeness, characterizes sets of logic devices that can be used for the construction of networks to represent any finite-state machine. Associated with this property is a rate of completeness, which is the maximum input sequence rate for which any finite-state machine can be constructed from the given set of devices. Tests for completeness are presented from which the completeness or lack thereof may be determined for certain classes of sets of devices. For complete sets of devices, these tests also determine the rate of completeness.
Dysregulated IP3 Signaling in Cortical Neurons of Knock-In Mice Expressing an Alzheimer's-Linked Mutation in Presenilin1 Results in Exaggerated Ca2+ Signals and Altered Membrane Excitability

Disruptions in intracellular Ca2+ signaling are proposed to underlie the pathophysiology of Alzheimer's disease (AD), and it has recently been shown that AD-linked mutations in the presenilin 1 gene (PS1) enhance inositol triphosphate (IP3)-mediated Ca2+ liberation in nonexcitable cells. However, little is known of these actions in neurons, which are the principal locus of AD pathology. We therefore sought to determine how PS1 mutations affect Ca2+ signals and their subsequent downstream effector functions in cortical neurons. Using whole-cell patch-clamp recording, flash photolysis, and two-photon imaging in brain slices from 4-5-week-old mice, we show that IP3-evoked Ca2+ responses are more than threefold greater in PS1(M146V) knock-in mice relative to age-matched nontransgenic controls. Electrical excitability is thereby reduced via enhanced Ca2+ activation of K+ conductances. Action potential-evoked Ca2+ signals were unchanged, indicating that PS1(M146V) mutations specifically disrupt intracellular Ca2+ liberation rather than reduce cytosolic Ca2+ buffering or clearance. Moreover, IP3 receptor levels are not different in cortical homogenates, further suggesting that the exaggerated cytosolic Ca2+ signals may result from increased store filling and not from increased flux through additional IP3-gated channels. Even in young animals, PS1 mutations have profound effects on neuronal Ca2+ and electrical signaling: cumulatively, these disruptions may contribute to the long-term pathophysiology of AD.
Extracting context to improve accuracy for HTML content extraction

Previous work on content extraction utilized various heuristics such as link to text ratio, prominence of tables, and identification of advertising. Many of these heuristics were associated with "settings", whereby some heuristics could be turned on or off and others parameterized by minimum or maximum threshold values. A given collection of settings - such as removing table cells with high linked to non-linked text ratios and removing all apparent advertising -- might work very well for a news website, but leave little or no content left for the reader of a shopping site or a web portal We present a new technique, based on incrementally clustering websites using search engine snippets, to associate a newly requested website with a particular "genre", and then employ settings previously determined to be appropriate for that genre, with dramatically improved content extraction results overall.
Complicating the Immigrant/Involuntary Minority Typology

Drawing on both international and U.S. studies, this article takes stock of what recent ethnographic research on immigrant and involuntary minority youth reveals about variability in school performance. Empirical reality proves to be far more complex than what can be explained through dichotomous typologies of accommodation and resistance, success and failure, or immigrant and involuntary minorities. Moreover, minority youth do better in school when they feel strongly anchored in the identities of their families, communities, and peers and when they feel supported in pursuing a strategy of selective or additive acculturation.
Transfusion medicine in philately

Among the myriad postage stamps issued throughout the world, many have depicted persons and events in medical history. Presented here are a number of examples from my collection of medical philately that illustrate individuals who have made contributions in the field of transfusion medicine. Also included are representations of various subjects relating to the specialty. For thousands of years, bloodletting has been carried out as a therapeutic procedure, although the transfusion of blood is a more recent method of treatment. In ancient Greece, Hippocrates promoted bloodletting, postulating that it rid the body of various “bad humors.” A stamp issued by Greece in 1977 with a picture from an Athenian vase from the fifth century BC (Fig. 1) depicts a physician about to incise the antecubital vein of a patient who is standing over a bleeding bowl. Shown on a stamp issued by Botswana in 1987 (Fig. 2) is bloodletting as a form of traditional medicine. Of course, bloodletting is carried out every day in medical institutions for diagnostic purposes. An example of this is seen on a stamp issued by Rwanda in 1963 (Fig. 3) for the centenary of the founding of the Red Cross. On a stamp from the Maldives (Fig. 4), a doctor is drawing blood from a young boy, while a nurse exerts pressure on the boy’s upper arm. Apparently, the doctor missed on his first try, as he is now attempting a venepuncture on the lateral aspect of the arm while the patient holds a cotton pledget with his forefinger over the antecubital fossa. The safe performance of blood transfusions was made possible by the discovery, of the ABO blood groups in 1900 by Karl Landsteiner. For this, he received the Nobel Prize in 1930. Landsteiner is shown on a stamp issued by the German Democratic Republic (East Germany) in 1968 (Fig. 5). Blood typing is seen on a stamp issued by Finland in 1972 (Fig. 6), and the blood groups are featured on a stamp issued in 1974 by Japan for International Red Cross Donation Year (Fig. 7). Another significant contribution to blood transfusion was the report, by Albert Hustin in 1914 of the use of sodium citrate and glucose as an anticoagulant. In 1915, Luiz Agote also described the use of sodium citrate to prevent the clotting of blood, which enabled the collection of blood and subsequent transfusion. Hustin was honored on a stamp issued by Belgium in 1977 (Fig. 8) and Agote on a stamp issued by Argentina in 1966 (Fig. 9). Transfusion medicine in philately
Systematic Review of Urologic Outcomes from Tethered Cord Release in Occult Spinal Dysraphism in Children

Tethered cord syndrome describes a condition of multisystem end organ dysfunction due to fixation of the spinal cord. This systematic review focuses on the closed skin variant of this condition, occult spinal dysraphism. The embryology, pathophysiology, presentation, and classification of occult spinal dysraphism are explained to develop a simple framework for discussions regarding this often confusing condition. Following Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines, we synthesized urologic outcome data after tethered cord release in children from 17 studies performed over the past 25 years. These results prompted several conclusions. First, the different subgroups and different nomenclature of tethered cord syndrome are often confused, making interpretation of results difficult. Second, untethering has a positive effect on urologic symptoms and urodynamics parameters. Third, timing of untethering is important: early intervention prevents significant long-term traction aiming to avoid irreversible neurologic damage. Fourth, pediatric urologists and neurosurgeons have an important role in diagnosing and treating this condition and should work closely as part of a multidisciplinary team.
Pedagogical approaches to student racial conflict in the classroom.

The majority of higher education faculty value diversity in the classroom; however, the majority of faculty also report making no or few changes in their classroom practices to deal with diversity issues. Faculty are in a position to facilitate classroom diversity in such a way that pedagogically avoids, supports, or challenges students’ learning about race and dealing with overt or covert racial conflict. Some faculty take on this challenge vigorously, while others approach it with considerable anxiety about their own knowledge or skills and students’ emotional reactions. This article explores some of the ways faculty address student conflict amid and around racial diversity in the classroom. Interviews with 66 faculty of different races and ethnicities, genders, and disciplines led to analyses of the various approaches they enacted and dilemmas they experienced in the face of such racial conflict. They include a range of decisions, such as: to avoid conflict through attempts to control the classroom environment; to minimize such conflict; to divert or distract students’ attention from conflict; to react to the conflict in a way that attempts to incorporate tensions for further learning; and to proactively design course activities to normalize and surface conflict in ways that enhance students learning about race and racial interactions. Examples and analysis of different ways of dealing with classroom racial diversity and conflict as well as the need for interventions to improve faculty members’ ability to deal with such situations are offered.
The Effect of a Solid Surface on the Segregation and Melting of Salt Hydrates

Considering the importance of salt and water on earth, the crystallization of salt hydrates next to solid surfaces has important implications in physical and biological sciences. Heterogeneous nucleation is driven by surface interactions, but our understanding of hydrate formation near surfaces is limited. Here, we have studied the hydrate formation of three commonly prevalent salts, MgCl2, CaCl2, and NaCl, next to a sapphire substrate using surface sensitive infrared-visible sum frequency generation (SFG) spectroscopy. SFG spectroscopy can detect the crystallization and melting of salt hydrates at the interface by observing the changes in the intensity and the location of the cocrystallized water hydroxyl peaks (3200-3600 cm(-1)). The results indicate that the surface crystal structures of these three hydrates are similar to those in the bulk. For the NaCl solution, the brine solution is segregated next to the sapphire substrate after the formation of the ice phase. In contrast, the MgCl2 and CaCl2 surface hydrate crystals are interdispersed with nanometer-size ice crystals. The nanosize ice crystals melt at much lower temperatures than bulk ice crystals. For NaCl and MgCl2 solution, the NaCl hydrates prefer to crystallize next to the sapphire substrate instead of the ice crystals and MgCl2 hydrates.
Technological Advances Shaping Scleral Lenses: The Boston Ocular Surface Prosthesis in Patients with Glaucoma Tubes and Trabeculectomies

The Boston Ocular Surface Prosthesis (BOS-P) (Boston Foundation for Sight, Needham, MA) is a fluid-ventilated rigid gas-permeable scleral lens that is utilized for the treatment of irregular corneal astigmatism and severe ocular surface disease. Recent reports have highlighted the utility of the BOS-P as a therapeutic device in cases of persistent epithelial defects, corneal neovascularization, ocular graft versus host disease, and exposure keratopathy. Patients with significant cornea disease might also have glaucoma, and those who have undergone glaucoma surgery, which typically disrupts the limbus, present a challenge when fitting the BOS-P. This report describes five patients with a history of both corneal disease and glaucoma surgery who were successfully fitted with the BOS-P.
The Nazi rag-pickers and their wine: the politics of waste and recycling in Nazi Germany

This article offers a first attempt to examine systematically the politics of waste and recycling in the Third Reich, one of the first modern states to articulate ‘zero waste’ as a political goal. It presupposes that waste, both in its material realities and its everyday representations, offers a powerful guide to any society's implicit order. With respect to Nazi Germany, the suggestion that such presumably neutral materials as trash, waste and garbage order social relations has particularly sinister implications. Focusing on scrap collectors and salvaging practices inside Germany and in Nazi-occupied Europe, this article argues that waste management and recycling were integral to the Nazi racial order and crystallized as central strategies to administer the chaos of war. Hundreds of thousands of volunteers in party, industry and society performed their loyalty and re-imposed order by collecting paper, bottles, metal scrap, kitchen garbage, rags and bones with the explicit goal of closing the energy cycl...
Asset Prices in Turbulent Markets with Rare Disasters

I propose a parsimonious econometric model for the stochastic process governing the evolution of per capita consumption and stock market dividend over time. The model features stochastic volatility of consumption and dividend growth rates, and time-varying likelihood of rare disasters. I embed this time-variation of risk in an endowment economy with a representative agent and estimate the parameters from U.S. stock market data using Maximum Likelihood. Allowing for time-varying likelihood of rare disasters improves the model's performance. My model successfully explains a number of empirical puzzles: the high equity risk premium, excessive volatility of equity return, predictability of market returns through the price-to-dividend ratio, and the cyclical patterns observed in the term structure of the yield on dividend strips. In addition, the model-implied correlations between equity premium, variance risk premium, and the implied volatility of deep OTM put options are consistent with empirical findings in the literature.
Transformation/Innovation or Patchwork? Juxtaposition of Public Policy Process and the Role of Leadership in a Chaotic Environment: Is a New Paradigm in the Make? (With Updated Postscript)

Public Policymaking processes are viewed by some as intertwined relationships of offices, public leaders, and issues, all of which constantly change in a kaleidoscope-like fashion as Gerston (2002) puts it nicely. With historically unprecedented economic debacle now facing U.S and the world the issue of public policymaking and its implementations come to the fore. At the same time the question of how the leadership of the society at the highest level has played such a decisive dysfunctional role in creating such fiasco and what the potentials are for a turn around occupies everybody’s mind. The tenet of this paper is to examine if new efforts and rescue plans, supposedly for bringing some order to the economy, will eventually result in fundamental and long term social and political changes in the very fabric of both public and market systems. A corollary to this is whether such long term changes - if materialize - would eradicate the old systems, and move toward a real transformation. Issues like the nature and processes of public policymaking, leadership in terms of power, transparency and accountability will be addressed with direct reference to the approaches adopted by Congress and President elect. An analysis of the new direction of public policy making and institutionalizing a kind of transformative leadership that permeate the whole public administration system is the crux of this paper’s argument. The updated postscript reveals how we are walking on a dangerous path in the face of recent events, like Congressional (Nov. 20110) escalating the chances that we are asking a recipe for disaster!
Employment-motivated migration and economic growth in post-industrial market economies.

The author reviews the literature on the relationship between migration and economic development in post-industrial market economies. Various models and theories concerned with this relationship are described and evaluated. Particular attention is paid to the relationship between migration and regional development (ANNOTATION)
Analysis of chromates for traces of Cr(III) by solvent extraction and inductively coupled plasma atomic emission spectrometry

A method for the determination of quantities of 0.5–500 μg of Cr(III) in the presence of chromates and dichromates is described. The samples are dissolved in an aqueous solution buffered at pH 7.0; the Cr(III) is selectively chelated with 2-thenoyltrifluoroacetone and extracted into xylene. The extracted chromium is analyzed using inductively coupled plasma emission spectrometry. Extraction of 1.0 μg Cr(III) from 5.0 mg K2Cr2O7 was accomplished and easily determined in a volume of 25 ml of xylene. The relative standard deviation for the determination of Cr(III) contents ranging from 4.0 × 10−8 g/ml to 2.0 × 10−8 g/ml was ± 0.079. Using a minimum signal to noise ratio of 10∶1, the detection limits of the method were determined to be approximately 2.0 × 10−8 g/ml xylene. Chloride, high surface area silica, and easily oxidized amorphous boron give rise to only minor interferences.
Plasma Lactic Dehydrogenase Activity in Experimental Hemorrhagic Shock.

Summary1. Marked elevations of plasma LDH activity in experimental hemorrhagic shock are described. An initial lag period is followed by a sharp rise to 15 to 50 times the original value. 2. Alterations of plasma LDH activity in shock bear a consistent relationship to such parameters of biological deterioration as rate of spontaneous return of blood from the reservoir to the animal (“taking up”) and reversibility to replacement transfusion. 3. Catheterization experiments in which consistent arterio-venous differences were demonstrated indicate that the sources of elevated plasma LDH activity are widespread and include liver, kidney and tissues of an extremity. 4. Electrophoretic separation of normal dog plasma reveals 4 enzymes with LDH activity. All 4 are elevated in plasma of dogs in shock. 5. Marked elevations of plasma GO-T, MDH and alkaline phosphatase were observed in dog plasma during hemorrhagic hypotension. No significant elevations in beta-glucuronidase, alpha-glucosidase, leucine aminopeptidase...
Tactical Conflict Resolution using Vertical Maneuvers in Enroute Airspace(ALTERNATE PAPER)

This paper discusses an algorithm for computing vertical resolution maneuvers to resolve imminent air traffic conflicts in which loss of separation could occur in less than two minutes. Several procedures are used, including rejection of altitude amendments that could cause a conflict, temporary altitudes, step altitudes, and critical leveloff confirmation. These methods were tested on archived data from 100 actual operational errors, which tend to be more difficult to detect and resolve than routine conflicts. Successful resolution was achieved in simulation for 84 of them using vertical maneuvers only. Augmented altitude amendments were then added to the input files to simulate altitude amendments that should have been entered by the controller but were not, or to correct amendments to make them consistent with the pilot’s understanding. The number of successful resolutions increased to 94 of the 100 cases.
The Regulation of Arachidonic Acid Release in Parturition

One of the rate limiting steps in prostaglandin biosynthesis is the release of free arachidonic acid (1,2). In the present investigation is described the results of a study in which: 1) we have defined the lipid species of the human fetal membranes that serves as the source of arachidonic acid for prostaglandin biosynthesis during human parturition; 2) we have defined the enzymatic mechanism involved in this release; 3) we have investigated the regulation of these processes with special emphasis on the possible inter-relationship between the fetal lung and fetal membranes, to the initiation of parturition. Several years ago we observed that the concentration of arachidonic acid increased disproportionally in human amniotic fluid during labor (3). It has been reported by numerous investigators that prostaglandins are produced in large amounts by uterine and intra-uterine tissues during parturition. We also demonstrated that the microsomal fraction prepared from several intra-uterine tissues, including amnion, and chorion laeve, had a high capacity for prostaglandin formation from arachidonic acid (4). We suggested that the source of the arachidonic acid was fetal membranes.
When is surgery necessary for a groin hernia

PreviewBefore referring a patient to a surgeon for repair of groin hernia, the primary care physician must decide if the benefits of surgery outweigh the risks. Most groin hernias are reducible and can be repaired on an elective basis. Others, however, are more prone to incarceration and strangulation and should be repaired promptly to avoid an emergency situation. Dr Berliner reviews the various types of groin hernia and discusses when repair can and cannot wait.
Death of a genre

How does a tradition end? Sometimes, like a language, a tradition dies with the last person who embodies it. After Samuel Johnson read James Boswell's Latin thesis for the Faculty of Advocates in Edinburgh, he remarked with characteristic bluntness, “Ruddiman is dead.” Thomas Ruddiman, printer, publisher, Latinist, and librarian of the Faculty, had corrected the Latin of the young advocates' works before they were formally submitted. Now he was gone – and with him the tradition of precise Latin scholarship that had inspired Ruddiman's edition of the works of George Buchanan. Scottish Neo-Latin died with Ruddiman. The crowd-pleasing death scene of the ars historica , by contrast, seems impossible to identify with that of a single individual or even the publication of a single deadly critical book. It is not hard to provide a terminus ante quem . On 22 December 1766, the Prorector and Senate of the University of Gottingen celebrated the opening of a Historical Institute, under the directorship of Johann Christian Gatterer, professor ordinarius of history. This institute promised the young scholars and aristocrats who flocked to the university the most up-to-date historical training in Europe – a training that Friedrich August Wolf applied to the creation of Altertumswissenschaft , and Wilhelm von Humboldt to the invention of that sublime product of German administrative ingenuity, the researchcentred University of Berlin. The great classical scholar Christian Gottlob Heyne celebrated the institute's creation in a powerful address.
Zur Theorie und Praxis des Föderalismus: Subsidiarität, Integration und der sanfte europäische Verfassungswandel

Der Foderalismus beruht bekanntlich auf den Grundprinzipien der Integration und Subsidiaritat. Diese Konzepte werden aber zumeist missverstanden, da die Geschichts- und Kulturbezogenheit sowie die inharenten politischen Spannungen des Foderalismus verkannt werden. Im Folgenden mochte ich das Subsidiaritatsprinzip und seine zwei Hauptkomponenten — die instrumentelle und materiale Zentralisierung bzw. Dezentralisierung — naher betrachten und kontextualisieren. Dies wird verdeutlichen, wie eng die materiale Komponente der Subsidiaritat — im Gegensatz zu der instrumentellen — mit einer ganz bestimmten Form der Integration, namlich einer verfassungsrechtlich gestalteten Integration zusammenhangt. Die genannten Grundprinzipien verweisen zugleich auf Grundsatzfragen jedes foderalen Systems, namlich die stetige Spannung zwischen den einander widerstreitenden Anspruchen auf Zentralisierung und auf Dezentralisierung sowie die Problematik der damit zusammenhangenden Verfassungsintegration, die letztendlich auf der normativen Gleichstellung der Burger verschiedener Gliedstaaten beruht.
Abstract 4442: Very low methylation is a novel epigenetic regulatory mechanism in normal tissues and predisposes to hypermethylation in cancer

High level DNA methylation of promoter CpG Island (CGI) represses gene expression. However, low-level CGI methylation is usually not distinguished from complete absence of methylation. Here we show that Very Low Methylated Regions (VLMRs 1-20%) on promoter CGIs are present in up to 20% of human and mouse genes and negatively correlate with gene expression in all tissues examined. In vitro, low-level methylation directly represses reporter gene expression; an effect mediated by methyl-CpG-binding proteins as transient knockdown of MBD4 reverses this repression. In vivo VLMR genes are enriched for polycomb occupancy but can also occur in H3K4me3 occupied promoters, where it correlates with gene repression independent of polycomb complex binding. VLMRs in promoter CGIs in healthy WBCs are 19 fold and 65 fold more likely to gain hypermethylation in Acute Myelogenous Leukemia and Myelodysplastic Syndrome patients respectively compared to unmethylated CGIs ( Citation Format: priyanka madireddi, Jaroslav Jelinek, Justin Lee, Takahiro Sato, Jean-Pierre Issa. Very low methylation is a novel epigenetic regulatory mechanism in normal tissues and predisposes to hypermethylation in cancer. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 4442.
Use of whole genome sequencing to identify highly recurrent somatic mutations in Waldenström’s macroglobulinemia.

8107 Background: Waldenstrom’s Macroglobulinemia (WM) is an IgM secreting lymphoplasmacytic lymphoma. The genetic basis for this disease remains to be clarified. Methods: We performed whole genome ...
Integration of power LDMOS into a low-voltage 0.5 mu m BiCMOS technology

Integration of a power Lateral Double Diffused MOS (LDMOS) structure into a high performance 0.5 mu m BiCMOS technology for high density, multi-functional integrated circuit (IC) applications is described. The advantages of VLSI processing and rules have been applied to the design and the manufacturing of the high density LDMOS without sacrificing the performance of 0.5 mu m dual-poly (n/sup +//p/sup +/) gate CMOS and polysilicon emitter bipolar (f/sub T/=26 GHz) transistors. The measured source to drain on-state resistance of the fabricated LDMOS is 90 m Omega -mm/sup 2/. Further device optimization, by means of 2D numerical simulations, can increase the breakdown voltage of the LDMOS to 60 V using this technology. >
Developmental Physical Education: How to Implement a Peer-assistance Program to Help Low Performers

Teachers want all students to succeed. As physical educators, the goal is to create physically literate students. However, what does a physical educator do when regular differentiation techniques are not enough to provide success for each student? This article provides a description of how one elementary school met the needs of low-performing physical education students who did not qualify for adapted physical education services. A step-by-step approach is explained regarding how any physical educator can implement such a program in his or her school. Potential steps for implementation include: (1) baseline assessment; (2) administrator, teacher and parent buy-in; (3) selection of little and big buddies; (4) follow-up assessment strategies; and (5) reflection and program evaluation.
Vaccination for Mycobacterium tuberculosis infection: reprogramming CD4 T-cell homing into the lung

Development of effective tuberculosis vaccines is hampered by insufficient understanding of protective immunity. Here, Woodworth et al.1 show secondary effector CD4 T cells generated after Mtb challenge of H56/CAF01 vaccinated mice display superior lung homing compared with primary effectors. Vaccination generates large populations of parenchymal lung effector cells by inducing CXCR3+KLRG1- cells that continuously migrate from lymph nodes to lung, and limiting the generation of non-protective CX3CR1+KLRG1+ intravascular effectors, providing insight vaccine-mediated protection against tuberculosis.
Patterns of gestational diabetes diagnosis inside and outside of clinical guidelines

Hospital discharge codes are often used to determine the incidence of gestational diabetes mellitus (GDM) at state and national levels. Previous studies demonstrate substantial variability in the accuracy of GDM reporting, and rarely report how the GDM was diagnosed. Our aim was to identify deliveries coded as gestational diabetes, and then to determine how the diagnosis was assigned and whether the diagnosis followed established guidelines. We identified which deliveries were coded at discharge as complicated by GDM at the Brigham and Women’s Hospital in Boston, MA for the year 2010. We reviewed medical records to determine whether the codes were appropriately assigned. Of 7883 deliveries, coding for GDM was assigned with 98% accuracy. We identified 362 cases assigned GDM delivery codes, of which 210 (58%) had oral glucose tolerance test (OGTT) results available meeting established criteria. We determined that 126 cases (34%) received a GDM delivery code due to a clinician diagnosis documented in the medical record, without an OGTT result meeting established guidelines for GDM diagnosis. We identified only 15 cases (4%) that were coding errors. Thirty four percent of women assigned GDM delivery codes at discharge had a medical record diagnosis of GDM but did not meet OGTT criteria for GDM by established guidelines. Although many of these patients may have met guidelines if guideline-based testing had been conducted, our findings suggest that clinician diagnosis outside of published guidelines may be common. There are many ramifications of this approach to diagnosis, including affecting population-level statistics of GDM prevalence and the potential impact on some women who may be diagnosed with GDM erroneously.
Saliency harmonic induction motor speed estimation using artificial neural networks

Several methods have been proposed to measure the speed of an induction machine without the need for external speed transducers. These sensorless methods typically use observers, require injected signals, or are dependent on the detecting a specific harmonic. This paper investigates using neural networks to identify the speed of a machine using a range of harmonics without specific knowledge of machine parameters. As a proof of concept currents measured from various machines are analyzed with the proposed method. This analysis showed that such a system has the potential for relatively accurate speed determination.
Lower extremity peripheral neuropathies in the rehabilitation patient

Lower extremity neuropathies can occur proximally, at the level of the lumbosacral plexus. Points of compression occur due to anatomical structures encountered through the course of each nerve, such as muscles and bones. Treatment can vary from conservative measures, to more invasive surgical interventions.
Real-Time Detection of In-flight Aircraft Damage

When there is damage to an aircraft, it is critical to be able to quickly detect and diagnose the problem so that the pilot can attempt to maintain control of the aircraft and land it safely. We develop methodology for real-time classification of flight trajectories to be able to distinguish between an undamaged aircraft and five different damage scenarios. Principal components analysis allows a lower-dimensional representation of multi-dimensional trajectory information in time. Random Forests provide a computationally efficient approach with sufficient accuracy to be able to detect and classify the different scenarios in real-time. We demonstrate our approach by classifying realizations of a 45 degree bank angle generated from the Generic Transport Model flight simulator in collaboration with NASA.
Review of Trends in Mobile Learning Studies in Mathematics: A Meta-Analysis

The field of mobile learning is growing an exponential rate. To best understand this field, it is crucial to gain a collective understanding of the research that has taken place. There are a number of recent studies which looked at collective trends in mobile learning across subjects. However, these results do not provide insight into specific subject areas. This meta-analysis reveals the trends in mobile learning in mathematics with a comprehensive analysis and synthesis of 48 studies from the year 2000 onward. Major findings include that most of the studies focus on effectiveness, followed by learning design. Mobile phones are currently the most widely used device used. Also, the use of mobile devices for mathematics learning is most common in elementary (5-11 years old) school settings.
New Insights from Elucidating the Role of LMP1 in Nasopharyngeal Carcinoma

Latent membrane protein 1 (LMP1) is an Epstein-Barr virus (EBV) oncogenic protein that has no intrinsic enzymatic activity or sequence homology to cellular or viral proteins. The oncogenic potential of LMP1 has been ascribed to pleiotropic signaling properties initiated through protein-protein interactions in cytosolic membrane compartments, but the effects of LMP1 extend to nuclear and extracellular processes. Although LMP1 is one of the latent genes required for EBV-immortalization of B cells, the biology of LMP1 in the pathogenesis of the epithelial cancer nasopharyngeal carcinoma (NPC) is more complex. NPC is prevalent in specific regions of the world with high incidence in southeast China. The epidemiology and time interval from seroconversion to NPC onset in adults would suggest the involvement of multiple risk factors that complement the establishment of a latent and persistent EBV infection. The contribution of LMP1 to EBV pathogenesis in polarized epithelia has only recently begun to be elucidated. Furthermore, the LMP1 gene has emerged as one of the most divergent sequences in the EBV genome. This review will discuss the significance of recent advances in NPC research from elucidating LMP1 function in epithelial cells and lessons that could be learned from mining LMP1 sequence diversity.
Prediction of pancreatic cancer surgical outcomes and prognosis based on an objective resectability scoring system.

446Background: There is no consensus on the best radiographic criteria to define pancreatic cancer (PCA) resectability. We undertook this study to objectively assess the probability of tumor resect...
Deliberative Crowdsourcing: Intelligence and Information Gathering Through Crowdsourcing

The hollowing of the state has added new challenges for administrators attending to the competing values of administration. This article examines how the wisdom of the crowds can be used in a deliberative manner to extract new knowledge through crowdsourcing. We will specifically examine cases of intelligence and information gathering through the analysis of a suspected nuclear reactor in Syria and the use of the crowd in mapping unknown or rapidly changing environments. Through case analysis, this article seeks to understand if crowdsourcing can offer a potential opportunity for public managers to reduce transactions costs while engaging the crowd in a form of deliberative governance to understand and potentially solve public problems. Our approach involves applying the seven lessons of deliberative governance (Scott, Adams, and Wechsler 2004) to our cases in order to produce five administrative concepts for creating mini-publics for deliberative crowdsourcing.
Review and update: robotic transanal surgery (RTAS)

As the field of surgery advances, new approaches have allowed surgeons additional flexibility to perform further interventions with minimal or no external incisions. For many years, single site access (SSA) has been used for transanal procedures, and platforms allowing modified endoscopic approaches have been available. These platforms have limitations related to access, visualization, dexterity, camera control, and instrumentation. Recently, surgical robotics companies have developed and introduced new technologies and platforms, which may help address some of these limitations. Comprehensive internet, open access, and medical and industry conference reviews of robotic surgery platforms and technology available for use in SSA surgery were conducted and 30 articles were found using keywords “robotic surgery, transanal, single site, robotic transanal surgery”. A PubMed, Medline, Journals @OVID and open access search for data related to these platforms and technologies was also performed yielding 11 articles. Abstracts were reviewed for those written in the English language, leaving 40 articles which were then filtered for those pertaining to robotic surgery, transanal. 58 abstracts were found, duplicates were eliminated, and the remaining 35 articles were read in their entirety by two reviewers. Several new and existing platforms are identified for use in SSA surgery for transanal surgery as well as abdominal and transoral surgery. These are reviewed, including brand, features, approved and suggested uses, and potential limitations. New robotic technologies serve to enhance the ability of surgeons to perform SSA surgery. This next generation of robotic surgery technology overcomes some of the limitations of preceding endoscopic SSA surgery technology and will enhance the advancement of robotic transanal surgery, but outcomes and performance data are still limited.
Capacity Predictions and Capacity Passenger Car Equivalents of Platooning Vehicles on Basic Segments

AbstractVehicle platooning is an innovative strategy that uses automated driving technology and communication to enable a more efficient use of transportation networks. By controlling tighter gaps ...
Impact of culinary medicine elective on medical students’ culinary knowledge and skills

Diet has an important role in the treatment and prevention of chronic illnesses. Physicians are regarded as having proficient knowledge about nutrition, but most believe that they lack an understan...
Abstract 613: Disturbed Flow-induced Telomeric Repeat Binding Factor 2 (terf2)-interacting Protein (terf2ip) K240 Sumoylation is Critical for Endothelial Senescence but Not Inflammation

Upregulation of both inflammation and senescence (Sen) of endothelial cells (ECs) in the disturbed flow area within the aortic arch is well established, but the exact mechanisms and the relationshi...
Considerations in implementing evidence-based early autism spectrum disorder interventions in community settings.

Evidence-based practices (EBPs) in early intervention for autism spectrum disorder (ASD) have the potential to improve children’s developmental trajectories and address family needs. However, the successful use of EBPs in community early intervention settings requires careful attention to the context in which services are delivered. Implementation science, and specifically the Exploration, Preparation, Implementation, and Sustainment (EPIS) Model, provides a framework to examine context across multiple levels and identify barriers and facilitators to community EBP use. This article identifies several considerations most relevant for early intervention in ASD at the outer and inner context levels, as well as bridging and innovation factors. Outer context considerations include the policies and funding streams surrounding service delivery, the role of advocacy in shaping the service landscape, the availability of appropriate specialists to provide services, and family cultural characteristics. Inner context factors include the individual characteristics of both the children receiving the service as well as the provider delivering the service, in addition to the leadership and organizational climate surrounding the use of a particular EBP. We also discuss considerations of the specific innovation (in this case, EBP early interventions) to be deployed, as well as bridging factors.
E-Hookah Versus E-Cigarettes: Findings From Wave 2 of the PATH Study (2014–2015)

Introduction ENDS are evolving quickly with increasing use in the U.S. More recently, e-hookahs have been introduced as healthier alternatives to the traditional hookah-flavored tobacco smoking. To date, virtually all studies of ENDS have focused on e-cigarettes; consequently, little is known about e-hookah use. Methods Data were drawn from the 2014–2015 Wave 2 Population Assessment of Tobacco and Health study, a nationally representative sample of adults aged ≥18 years (n=28,362) and youth aged 12–17 years (n=12,172). Weighted analyses, conducted in 2018–2019, estimated the prevalence of e-hookah versus e-cigarette and examined comparisons among users and sociodemographics, patterns of use, and co-use of tobacco products and substances. Results Overall, 4.6% of adults reported ever e-hookah use; of these, more than a quarter (26.8%) reported current use. For e-cigarettes, 22.5% reported ever use with 24.8% reporting current use. Among youth, 7.7% reported ever e-hookah use versus 14.3% for e-cigarette use. Comparing e-hookah versus e-cigarette only users, the majority were young adults aged 18–24 years versus ≥25 years (60.5% vs 17.3%, p Conclusions Although e-hookahs are used less commonly than e-cigarettes, e-hookah use is not rare. Compared with e-cigarette users, e-hookah users have a different profile in terms of user demographics and co-use of substances. Given the rapid uptake of ENDS by young adults, these findings suggest the need to understand e-hookah products’ distinct characteristics and users’ smoking patterns and behaviors to help inform tobacco regulation specific to hookah.
Fundamental Issues in Magnetoelectric Transducers: Magnetic Field Sensing Versus Wireless Power Transfer Systems

This paper presents theoretical analysis on fundamental performances of two configurations of magnetoelectric transducers that are used the most in practice, longitudinal-longitudinal and longitudinal-transverse modes, with a focus on magnetic field sensing and wireless power transfer applications. Based on equivalent circuit models and two-port network theory, we derive explicit closed-form solutions for the magnetoelecitric voltage coefficient and the power delivered to a load. We reveal that although the former configuration exhibits some advantages of utilizing as a sensing system, there is no difference in the maximum output power obtained from the two methods. The question on how to reach the upper bound on transferred power is also discussed. The findings can be used as a generalized framework to design an optimal system, depending on desired applications.
Withdrawing and Drawing In: Political Discourse in Policed Communities

A growing body of literature examines how direct or vicarious contact with forms of state surveillance affects political behavior and perceptions of government legitimacy. We develop a new method, Portals, to collect conversations between black residents from highly policed areas in five different U.S. cities between 2016 and 2018. While existing research emphasizes how interactions with the carceral state are alienating and demobilizing, our analysis of these conversations identifies productive ways in which citizens respond to oppressive encounters with police. The political discourses used by Portals participants, we argue, are centered on a logic of “collective autonomy”—given police ignorance, abuses of police authority, and the little political power that residents of highly policed communities have to demand change, many conclude that power is best achieved by strategically distancing from state institutions in the short term while building community power in the long term. Crucially, articulations of collective autonomy transcend the ideological positions of participants and track closely with an ideological tradition in black politics that persists across generations and contexts of state oppression.
Analysis and Control of Power–Temperature Dynamics in Heterogeneous Multiprocessors

Virtually, all electronic systems try to optimize a fundamental tradeoff between higher performance and lower power consumption. The latter becomes critical in mobile computing systems, such as smartphones, which rely on passive cooling. Otherwise, the heat concentrated in a small area drives both the junction and skin temperatures up. High junction temperatures degrade the reliability, while skin temperature deteriorates the user experience. Therefore, there is a strong need for a formal analysis of power consumption-temperature dynamics and predictive thermal management algorithms. This article presents a theoretical power–temperature analysis of multiprocessor systems that are modeled as multi-input multi-output dynamic systems. We analyze the conditions under which the system converges to a stable steady-state temperature. Then, we use these models to design a control algorithm that manages the temperature of the system without affecting the performance of the application. Experiments on the Odroid-XU3 board show that the control algorithm is able to regulate the temperature with a minimal loss in performance compared with the default thermal governors.
First Do No Harm: Ethical Concerns of Health Researchers That Discourage the Sharing of Results With Research Participants

Background: Health researchers and health research participants support the sharing of research results; however, results are typically only shared through peer-reviewed publications. Few studies h...