cssi/SciSciGPT-SciSciNet huggingface dataset:
A Study on Career Choice of Management Undergraduate Students in Trincomalee Campus

This paper aims to explore the study on career choice of Management Undergraduate Students in Trincomalee Campus. Selecting one’s career wisely and rightly is a core factor for performance, individual satisfaction and societal wellbeing. Identifying what determines career choice among undergraduates can have many benefits. Therefore, this study aims at exploring the influence of various factors on career choice decision making among Management Undergraduates in Trincomalee Campus. The existing literature in this regard, within the study context, is skeletal, and that this study, having explained about the socio-demographical composition of Management Undergraduates, achieved four research objectives; to assess the level of career choice among Trincomalee Campus Management Undergraduates; to identify the priorities of factors affecting career choices; to assess the influence of such career choice factors on level of career choices among Management Undergraduates in Trincomalee Campus and to establish the correct career choice that develop the social and economic situation of a country. A simple random sampling method is used to select participants for this study. A quantitative approach is used in this study. Accordingly, data are collected using a questionnaire, designed in a Likert’s scale method. This study is limited to students who are in Trincomalee Campus, especially Management Students. In this study, four variables are used to measure the factors influencing on career choice of Management Undergraduates in Trincomalee Campus. To attain the objectives, the quantitative method is used and data are collected through questionnaires. A total of 100 questionnaires are distributed to students who were in Trincomalee Campus. The data are analyzed using statistics. The findings exhibited that, Personal Factors, Social & Technical Factors, Job related Factors and Campus Related Factors influencing on career choice of Management undergraduates in Trincomalee Campus. This paper fulfills an identified implication guided the authors to recommend strong career development activities by the universities through their curricula and out of curricula activities to create career awareness of the most demanding and prioritized careers while motivating the graduates to accept such available careers.
Bhaskar's Philosophy as Anti-Anthropism

This article aims to contribute to the understanding of Roy Bhaskar's philosophical evolution from critical realism to the philosophy of meta-Reality. Following Bhaskar's own terminology, I define his intellectual journey as the ‘identification of dualism and duality within non-duality’ by proposing that anti-anthropism plays a key role in the developmental consistency of his system from critical realism via dialectical critical realism to meta-Reality. For this purpose, I compare Bhaskar's philosophy with Andrew Collier's theory of human rationality and spiritual emancipation based on Christianity and Tu Wei-Ming's anthropocosmic understanding of human beings and nature based on Confucianism.
Left Ventricular Ejection Time Derived From the Common Carotid Artery Doppler Waveform Association With Left Ventricular Ejection Fraction and Prediction of Heart Failure

Objectives—Left ventricular ejection time (LVET) is measured from blood pressure tracings as the interval from end diastole to the dicrotic notch and shows associations with left ventricular ejection fraction (LVEF) and heart failure. LVET can be measured on common carotid artery Doppler waveforms. We therefore studied the possible associations of common carotid artery LVET with LVEF measured by echocardiography and heart failure. Methods—We performed a retrospective study of 110 patients who had transthoracic echocardiography and carotid Doppler evaluations within 1 day of each other. LVEF was determined by the biplane modified Simpson method. LVET was measured from left common carotid artery Doppler tracings. Linear regression was used to evaluate associations between LVET and LVEF. We also used logistic regression with LVEF of less than 40% as a cut point for heart failure to generate a receiver operating characteristic curve, estimate the area under the curve, and calculate sensitivity and specificity. Results—LVET was associated with LVEF (P < .0001). The area under the curve of LVET for heart failure was 0.81 (95% confidence interval [CI], 0.72–0.87), and the sensitivity and specificity were 76.9% (95% CI, 65.4%–88.4%) and 65.5% (95% CI, 53.4%–77.8%), respectively, for LVET of 321 milliseconds. Conclusions—LVET measured on common carotid artery Doppler tracings decreases with LVEF and is strongly associated with prevalent heart failure. Based on what is known of blood pressure–measured LVET, common carotid artery Doppler waveform– derived LVET could be used to serially monitor cardiac function.
Near Infrared Autofluorescence Imaging of Retinal Diseases

Near infrared autofluorescence (excitation 787 nm, emission >800 nm) is a non-invasive imaging technology that provides information on the distribution of melanin within the retinal pigment epithelial cell/choroid complex. This review contains an introduction to near infrared autofluorescence imaging methods. Characteristics of near infrared imaging in a variety of retinal diseases, including age-related macular degeneration, choroidal nevus, retinal degenerations, retinal dystrophies, central serous chorioretinopathy, pseudoxanthoma elasticum and chloroquine retinopathy, are summarized.
Cue-evoked positive affect, depression vulnerability and smoking years.

OBJECTIVES To evaluate whether cue-evoked affective response would moderate the relationship between depression-proneness and smoking years. METHODS Depression-proneness profiles were derived using clinician diagnosed personal and family histories of major depression, recurrent depression, trait-anhedonia, and ruminative coping styles (n=70). Affective distress was produced by idiographic, guided negative mood imageries in the presence of an in vivo cigarette exposure. RESULTS Contrary to expectations, results showed that individuals less vulnerable to depression reported longer smoking histories. Stress-induced decreases in positive affect bolstered the association between depression vulnerability and smoking years. CONCLUSION Depression-proneness assumptions are challenged and implications to affective influences on smoking behavior are discussed.
Awakenings: The Emergence of White Supremacist Ideologies

Scholarly treatments of white supremacy have tended to focus on groups over individuals, examining belief systems, framing mechanisms, and operational dynamics. White supremacist discourse and dialogue often include descriptions of the processes through which one “awakens” to support these ideologies. This article considers how individuals report discovering their affinity for white supremacist belief systems. Data are culled from personal accounts available on Web pages, postings to electronic discussion forums, literature published by white supremacist groups, and biographical/autobiographical works. The authors discuss the common themes emerging from accounts of personal “awakenings” to better understand how adherence to white supremacist ideologies emerges within the individual. Implications for broader understandings of white supremacy are discussed.
Application of autoregressive modeling in proper orthogonal decomposition of building wind pressure

Application of autoregressive (AR) modeling in study of the results of proper orthogonal decomposition (POD) of wind-induced pressure on a low-rise building is described in the paper. The POD principal coordinates (PC) were obtained for point pressure measured simultaneously at 495 taps on the surface of a model of a low-rise building. The AR models were next fitted for the first four PC, and they were compared with the AR models developed for point pressure at representative taps on the building windward wall and roof. It was found that the order of the AR required for the principal coordinates was relatively low, and it did not exceed the order of the AR established for the considered point pressure.
RAMAN SPECTRA FROM SATURATED WATER VAPOR TO THE SUPERCRITICAL FLUID

Raman OH stretching peak frequencies from saturated water vapor decrease by about 20−30 cm-1 as monomers (OH peak frequency, 3657 cm-1) are replaced by dimers (diagnostic frequency ≤ 3628−3638 cm-1...
Filamentary and hierarchical pictures - Kinetic energy criterion

We present a new criterion for formation of second-generation filaments. The criterion called the kinetic energy ratio, KR, is based on comparison of peculiar velocities at different scales. We suggest that the clumpiness of the distribution in some cases might be less important than the 'coldness' or 'hotness' of the flow for formation of coherent structures. The kinetic energy ratio is analogous to the Mach number except for one essential difference. If at some scale KR is greater than 1, as estimated at the linear stage, then when fluctuations of this scale reach nonlinearity, the objects they produce must be anisotropic ('filamentary'). In the case of power-law initial spectra the kinetic ratio criterion suggests that the border line is the power-spectrum with the slope n = -1.
Numerical Modeling of the V(z) Curve for a Thin-Layer/Substrate Configuration

Abstract A numerical model is presented to calculate V(z) curves for a line-focus acoustic microscope and the specimen configuration of a thin isotropic elastic layer deposited on an isotropic elastic substrate. In this model, a Gaussian beam which is tracked through the lens into the coupling fluid, interacts with the thin-layer/substrate system. The numerical approach is based on the solution of singular integral equations by the boundary element method. The system of singular integral equations follows from the conditions at the interface of the coupling fluid and the thin layer and the interface of the thin layer and the substrate. An electrochemical reciprocity relation is used to express the voltage at the terminals of the microscope's transducer in terms of the calculated incident and back-scattered fields. V(z) curves are presented for various layer thicknesses and various combinations of the elastic constants of the layer and the substrate. The oscillations of the V(z) curves are related to the m...
Neuroleptic Plasma Levels

There is enormous variation in plasma levels of most neuroleptics in patients on the same dose. Much of the past research on the relation between plasma levels of antipsychotic drugs and clinical change, however, has been difficult to interpret. It does appear that decreased bioavailability, at least in public institutions, is rarely the cause of treatment failure. Aberrantly low plasma levels are more likely due to surreptitious noncompliance or drug interactions with enzyme inducers such as carbamazepine. Therapeutic plasma level ranges, in which good antipsychotic effect occurs without undue side effects, have been tentatively identified for perphenazine, haloperidol, fluphenazine, and chlorpromazine. The extent to which aberrantly high plasma levels are associated with inferior antipsychotic response is unclear. Antipsychotic plasma levels may be most useful when the distinction between side effects and worsening psychosis is unclear. The utility of high neuroleptic plasma levels in the treatment-resistant patient is unclear.
An analysis of the temperature distribution in finite solid-state laser rods

An expression for the time-dependent temperature distribution in a finite solid-state laser rod, for an arbitrary distribution of pump energy, has been derived. The specific case of end pumping by circular (constant) or Gaussian beams is included. This formulation was used to predict the time evolution of temperature in Ti:sapphire laser rods and in Nd:YAG rods of specific dimensions. >
Awe of God, Congregational Embeddedness, and Religious Meaning in Life

Researchers have argued for some time that emotions play a significant role in religious life. The purpose of this study is to focus on a religious emotion—awe of God—that has received relatively little attention in the literature. A latent variable model was developed to assess the following core relationships: (1) people who attend worship services more often will be more likely to experience awe of God; (2) greater awe of God will promote a greater sense of congregational cohesiveness (i.e., the belief that fellow church members share common values and beliefs); (3) individuals who participate in cohesive congregations will be more likely to feel they belong in the place where they worship; and (4) a greater sense of belonging in a congregation will be associated with a stronger sense of religious meaning in life. Analysis of data provided by a nationwide sample of middle-aged and older adults provides support for each of these relationships.
Organizational Differences in Managerial Compensation and Financial Performance

This study had two general focuses. First, after reviewing the literature on compensation strategy, we examined the extent to which organizations facing similar conditions make different managerial compensation decisions regarding base pay, bonus pay, and eligibility for long-term incentives. Second, working from expectancy and agency theory perspectives, we explored the consequences of those decisions for organizational performance. Using longitudinal data on about 14,000 top-and middle-level managers and 200 organizations, we found significant differences between organizations. Our results suggest that organizations tend to make different decisions about pay contingency, or variability, rather than about base pay. Findings indicate that contingent pay was associated with financial performance but base pay was not.
The Role of Ultraviolet Radiation in Promoting the Palladium-Catalyzed Oxidation of Carbon Monoxide.

The photoenhancement of the oxidation of carbon monoxide over palladium has been studied at low and high pressures in the temperature range 300 to 443/sup 0/K. At a total pressure of 20 Torr there is a marked photoenhancement of the rate while at pressures below 10/sup -4/ Torr no enhancement was detectable. A correlation of these data and infrared spectroscopic data is established which suggests that a weakly bound state of CO is intimately involved in the photoenhancement process. The temperature dependence of the photoeffect is discussed.
Dynamic coronary blood flow reduction: supply side considerations

The pathophysiologic basis for transient myocardial ischemia was traditionally considered an inability to increase myocardial oxygen delivery during periods of augmented demand. In most instances, this was due to hydraulic obstruction imposed by important atherosclerotic coronary artery disease. Recently, information emerged to indicate that many episodes of transient myocardial ischemia were not necessarily preceded by an increase in myocardial oxygen demand. In these episodes, a primary reduction in oxygen delivery was found to be an important additional mechanism responsible for transient ischemia. The physiological mechanisms responsible for transient reduction in myocardial oxygen supply and their potential clinical importance are the subject of this review. A number of mechanisms can result in a temporary reversible reduction in myocardial oxygen supply. They may be arbitrarily divided into factors directly dependent on the coronary vasculature and those secondary to a more generalized hemodynamic disturbance (such as hypotension, anemia, etc.). This review will deal with coronary vascular mechanisms. These vascular mechanisms are sub-divided into those which involve large epicardial vessels and those involving smaller intramyocardial vessels.
Quantitative Ultrasound: An Indicator of Osteoporosis in Perimenopausal Women

The key to effective treatment of osteoporosis is early detection; however, the disease in perimenopausal women is frequently undiagnosed. To assess the utility of quantitative ultrasound (QUS) at the calcaneus in perimenopausal women, broadband ultrasound attenuation (BUA); speed of sound (SOS); quantitative ultra-sound index (QUI), an algorithm of BUA and SOS; and bone mineral density by dual X-ray absorptiometry (DXA) of the posteroanteiror spine, femoral neck, and total hip were measured in 420 women (ages 45-55 yr). Thirty (7.1%) of the women were found to be osteoporotic by DXA. All QUS measurements were predictors of osteoporosis. QUS values did not differ between postmenopausal women on estrogen replacement therapy (ERT) and those not on ERT. There were no differences among BUA, SOS, and QUI in the area under the receiver operating characteristic curves for predicting osteoporotic vs nonosteoporotic cases. At a QUI of 89, ultrasound had an 80% sensitivity for the diagnosis of osteoporosis, but only a 74% specificity. The use of QUS in perimenopausal women will facilitate the identification of women with osteoporosis. However, the high false-positive rate (26%) limits the utility of QUS as the sole diagnostic technique on which to base therapeutic decisions. Nevertheless, low QUS measurements may provide a means for targeting those women who would benefit most from more extensive evaluation (e. g., DXA).
The biokinetic behavior of 95mTc in juvenile Coho Salmon, Oncorhynchus kisutch (Walbaum)

Juvenile coho salmon, Onchorynchus kisutch, were exposed to 95mTc in both saltwater and freshwater to study the biokinetic behavior of this element in an anadromous fish. In freshwater, equilibrium whole-body concentration factors (CF5) ranged from 28 to 32 in two separate experiments, in sharp contrast to an equilibriumCF of < 5 in saltwater. While the uptake kinetics were unimodal in saltwater, in freshwater, biomodal uptake kinetics were observed. Technetium-95m retention was biphasic in freshwater depuration experiments, an initial rapid loss of 21% to 26% of the steady-state activity with an elimination half-life of 3 to 5 days was followed by a slower loss rate, with a whole-body elimination half-life ranging from 23 to 33 days. In saltwater, retention was monophasic with an elimination half-life of 5–16 days. Dramatic decreases in 95mTc body burdens when freshwater-labeled fish are transferred to Tc-labeled saltwater indicate that the changes in physiology accompanying saltwater acclimation lead to the loss of 95mTc.
Solubility of Anthracene in Binary Alcohol + 2-Pentanol and Alcohol + 4-Methyl-2-pentanol Solvent Mixtures

Article on the solubility of anthracene in binary alcohol + 2-pentanol and alcohol + 4-methyl-2-pentanol solvent mixtures.
Light scattering by rectangular solids in the discrete-dipole approximation: a new algorithm exploiting the Block–Toeplitz structure

The discrete-dipole approximation is used to study the problem of light scattering by homogeneous rectangular particles. The structure of the discrete-dipole approximation is investigated, and the matrix formed by this approximation is identified to be a symmetric, block-Toeplitz matrix. Special properties of block-Toeplitz arrays are explored, and an efficient algorithm to solve the dipole scattering problem is provided. Timings for conjugate gradient, Linpack, and block-Toeplitz solvers are given; the results indicate the advantages of the block-Toeplitz algorithm. A practical test of the algorithm was performed on a system of 1400 dipoles, which corresponds to direct inversion of an 8400 × 8400 real matrix. A short discussion of the limitations of the discrete-dipole approximation is provided, and some results for cubes and parallelepipeds are given. We briefly consider how the algorithm may be improved further.
ANALYSIS OF SCORE CHANGE PATTERNS OF EXAMINEES REPEATING THE GRADUATE RECORD EXAMINATIONS GENERAL TEST1

The stability of scores over time of the GRE® General Test verbal, quantitative, and analytical measures were studied using data from the self-selected group of repeaters. Overall, in these analyses the new-format GRE verbal measure demonstrated the greatest stability over time and the new-format analytical measure the least.
What happens when an ice sheet melts

The great ice sheets covering Antarctica and Greenland have enough frozen water locked in them to raise the global sea level by some 70 metres. The West Antarctic Ice Sheet may be inherently unstable and if it collapses the universal belief is that it would raise sea levels by 5–6 metres globally. But that estimate is wrong. What happens to sea levels when an ice sheet melts is complex and surprising. In some places, even, levels can go down. Jonathan Bamber explains.
Timing-jitter in high bit-rate WDM communication systems due to PMD-nonlinearity interaction

We show that the interaction of polarization-mode-dispersion and cross-phase-modulation in 10 and 40 Gbit/s WDM systems results in a significant timing-jitter, even in the absence of a PMD compensator. An acceptable PMD level can generate unacceptable jitter in WDM systems.
Characterization of VPO Catalysts by X-Ray Photoelectron Spectroscopy

Methods are described for determining the P/V ratio and average vanadium oxidation state in vanadium phosphates using X-ray photoelectron spectroscopy. The determination of P/V ratios are based on a calibration derived from five organometallic complexes containing vanadium and phosphorus. The vanadium oxidation state is shown to be related to the splitting between O(1s) and V(2p3/2) transition centroids, Vox = 13.82 − 0.68,[O(1s) − V(2p3/2)]. A simple calculation is presented, which reveals that the layered structure of (VO)2P2O7can lead to an apparent 14% phosphorus enrichment when the surface is assumed to terminate with pyrophosphate groups. Exposure of β, γ, and δ VOPO4phases to increasing concentrations of butane in 10% O2/N2results in transformation of the phases to vanadium pyrophosphate, as evidenced by the shifts in the P(2p) photoelectron transitions. During the transformation, the X-ray photoelectron spectroscopy P/V ratio in β-VOPO4increases by ca. 40%, whereas a much smaller increase is observed for the γ and δ phases. As prepared and under oxidizing conditions, the surface of β VOPO4has P/V < 1.
The geology of the angareb ring dike complex, northwestern ethiopia

The Angareb Ring Dike Complex is located in Begemder Province in northwestern Ethiopia, 55 kilometers NNW of the provincial capital Gondar. The structure was first identified in 1973 from Landsat 1 satellite imagery analysis of the East African Rift System.
“Half In, Half Out:” Gang Families, Gang Affiliation, and Gang Misconduct

Recently developed inmate behavior frameworks have expanded the discussion from deprivation/importation models to a life-course perspective. DeLisi and associates (International Journal of Offender Therapy and Comparative Criminology 55;1186–1207, 2011) presented the life-course importation model of inmate behavior based on a sample of state incarcerated offenders; however, their analyses were unable to distinguish indirect and direct effects of delinquent career and distal family background factors. The current study builds on the life-course importation model of inmate behavior by using path analysis to understand the direct and indirect effects of distal pre-incarceration indictors on gang-related inmate misconduct for 2,520 incarcerated youthful offenders. The findings lend support to the life-course importation model as the familial gang indicator was associated directly with individual gang affiliation, gang affiliation was associated directly with gang-related misconduct, and familial gang associations was associated indirectly with gang-related misconduct.
Multivariate Decision Trees

Unlike a univariate decision tree, a multivariate decision tree is not restricted to splits of the instance space that are orthogonal to the features' axes. This article addresses several issues for constructing multivariate decision trees: representing a multivariate test, including symbolic and numeric features, learning the coefficients of a multivariate test, selecting the features to include in a test, and pruning of multivariate decision trees. We present several new methods for forming multivariate decision trees and compare them with several well-known methods. We compare the different methods across a variety of learning tasks, in order to assess each method's ability to find concise, accurate decision trees. The results demonstrate that some multivariate methods are in general more effective than others (in the context of our experimental assumptions). In addition, the experiments confirm that allowing multivariate tests generally improves the accuracy of the resulting decision tree over a univariate tree.
Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults.

Abstract Background: Coenzyme Q10 (CoQ) is an endogenous enzyme cofactor, which may provide protective benefits as an antioxidant. Because age-related CoQ changes and deficiency states have been described, there is a need to establish normal ranges in healthy children. The objectives of this study are to determine if age-related differences in reduced CoQ (ubiquinol), oxidized CoQ (ubiquinone), and CoQ redox state exist in childhood, and to establish reference intervals for these analytes in healthy children. Methods: Apparently healthy children (n=68) were selected from individuals with no history of current acute illness, medically diagnosed disease, or current medication treatment. Self-reported healthy adults (n=106) were selected from the ongoing Princeton Follow-up Study in greater Cincinnati. Participants were assessed for lipid profiles, ubiquinol concentration, ubiquinone concentration, total CoQ concentration, and CoQ redox ratio. Results: Mean total CoQ and ubiquinol concentrations are similar in younger children (0.2–7.6 years) and adults (29–78 years); however, lipid-adjusted total CoQ concentrations are significantly increased in younger children. Also CoQ redox ratio is significantly increased in younger and older children compared with adults. Conclusions: Elevated CoQ and redox ratios in children may be an indication of oxidative stress effects, which are associated with early development of coronary heart disease.
Paralytic ileus as a result of diltiazem treatment.

. Diltiazem is a widely used calcium channel blocker, and has been found to be effective in the treatment of hypertension, stable, variant and unstable angina, as well as oesophageal spasm. Calcium channel antagonists have been shown to diminish the contractility of gut smooth muscle, but have not as yet been reported to cause clinically significant inhibition of gut motility when used alone. We report a case of reversible functional intestinal obstruction, immediately following diltiazem treatment in a patient with ischaemic heart disease.
Altered beta diversity in post‐agricultural woodlands: two hypotheses and the role of scale

Agricultural land use commonly leaves a persistent signature on the ecosystems that develop after agricultural abandonment. Th is agricultural legacy limits the biodiversity supported by post-agricultural habitats compared to remnant habitats that have never been used for agriculture. In particular, beta diversity (variation in community composition across space) at both large and small spatial scales can diff er between post-agricultural and remnant habitats, but we do not understand the mechanisms driving these diff erences. We surveyed plant communities at 29 pairs of post-agricultural and remnant longleaf pine woodlands (58 total woodlands) to test for patterns consistent with two hypothesized mechanisms for why post-agricultural ecosystems support altered beta diversity. 1) Post-agricultural sites support diff erent levels of underlying environmental heterogeneity than remnants. 2) Establishment of species associated with remnant habitats into postagricultural woodlands is limited by dispersal and/or environmental conditions. We found no support for the environmental heterogeneity hypothesis and strong support for the idea that species establishment limits reassembling communities. Our results revealed a novel and important nuance to the establishment limitation hypothesis: spatially constrained, but not completely prevented, re-establishment of remnant-associated species in post-agricultural woodlands increased within-site beta diversity, contrary to results at larger among-site (landscape) scales. Our use of a powerful paired-site design permits these insights into how agriculture and abandonment aff ect beta diversity at two spatial scales, highlighting the prominent infl uence of edges even a half century after agricultural abandonment. Th e importance of constrained species establishment during ecosystem recovery, and its scale-dependent eff ect, could provide valuable guidance to enhance the utility of post-agricultural habitats for biodiversity conservation.
Properties of rattlesnake shaker muscle.

The goals of this study were to learn something of the physiology of the rattlesnake's rattling mechanism and the mechanical properties of tension development. Using the rattlesnakes, Crotalus atrox and Crotalus scutulatus, it was found that the rattling motion is a complex oscillation rather than the simple back and forth motion often described. Rattling is accomplished by “doublet” contractions, i.e., if the shaker muscles on one side of the tail contract, then so do the muscles on the other side. The time interval between the two members of a doublet is temperature dependent and is the ultimate determinant of maximum rattling speed. The rattling is not produced by asynchronous type muscle such as found in insects. The isometric twitch is extremely fast at 18°C, and the contraction time is on the order of 8–10 msec. The rattlesnake shaker muscle at 18°C produces 0.3 kg/cm2 tension and has a twitch-tetanus ratio of 0.19. The length-tension curve for the active muscle is typical for skeletal muscle, but there is a larger passive resistance to stretch like that found in insect fibrillar flight muscle or cardiac muscle.
An Examination of Charter School Equity.

Many charter schools have arisen in urban areas, and they appear to enroll more students of color and low-income youth. In this article, the authors investigate the implications of charter school c...
Hepatic antigen-presenting cells and regulation of liver transplant outcome

In the steady state, hepatic antigen (Ag)-presenting cells (APC) generally dampen systemic inflammatory responses to gut-derived Ags. Our studies focus on the role of specific liver APC populations, both non-parenchymal cells (dendritic cells [DC], Kupffer cells, and hepatic stellate cells [HSC]) and parenchymal cells, in the molecular regulation of tissue damage (ischemia and reperfusion [I/R] injury) and immunity following liver transplantation. We focus on factors that either promote or overwhelm the natural tendency of the liver to suppress inflammatory/immune responses. We are also examining molecular mechanisms that regulate liver DC maturation and function and that determine their role in the control of allogeneic T-cell function and the fate of the transplanted liver. Our studies are also aimed at elucidating mechanisms by which HSC regulate DC and T-cell function. These investigations may provide new targets for therapeutic intervention in liver inflammation.
Rock Elm structure, Pierce County, Wisconsin: A possible cryptoexplosion structure

The Rock Elm structure is a nearly circular feature in western Wisconsin flat 44°43′N, long 92°14′W) in an area of otherwise little-deformed Cambrian and Ordovician shallow-marine sediments. The structure has a ring boundary fault with at least 50 m of vertical displacement, a sediment-filled ring basin, and central denial uplift. The ring basin fill consists of a shale-sandstone sequence of probable Ordovician age not found outside of the structure. Blocks of deformed Lower Ordovicisin carbonates are generally in angular unconformity beneath the basin fill but locally are in fault contact against basin-fill rocks. The central dome consists of conglomeratic sandstones, tentatively identified as the Upper Cambrian Mount Simon Sandstone, that have been uplifted more than 250 m. Although the deformation of the rocks is unusual for the region, there have been no shock-metamorphic features yet found associated with the structure. The Rock Elm structure has the essential features of a cryptoexplosion structure as described by Dietz and by McCall. Conclusive evidence is lacking as to whether the Rock Elm structure formed as a result of a bolide impact, explosive volcanic event, or other localized violent geologic event.
LABORATORY STUDIES IN PATIENTS WITH REYES SYNDROME

Fifteen patients with Reyes Syndrome were prospectively studied according to a protocol designed to describe the course of the illness biochemically. Therapy consisted of careful fluid, electrolyte, acid-base and respiratory management. All patients demonstrated an increase in blood FFA (m = 3.1 meq/L), blood lactate (m = 2.8 mM), blood β-hydroxybutyrate (m = 1.5mM) and a decrease in plasma triglycerides (m = 38 mg%). The magnitude of these changes in stages II or III did not differentiate between ultimate survivors and non-survivors. Hypoglycemia occurred in two patients and was easily corrected by the administration of 5% glucose. This metabolic pattern is compatible with the hypothesis that Reyes Syndrome is characterized by a deficiency of glucose oxidation. If this hypothesis is correct, then the other observed abnormal laboratory findings (eg. an increase in serum CPK, amylase, and OCT activities an elevation in blood NH3 concentration; abnormal EEG, ST and T wave changes on EKG) which are accepted features of the illness may reflect multiple organ system involvement by the same process. A decrease in blood β-hydroxybutyrate concentration, suggesting a failure of ketogenesis, occurred in 5/5 clinical stage IV patients who ultimately expired. Decreased glucose oxidation appears to play role in the pathogenesis of Reyes Syndrome.
An investigation of lens opacity on personnel operating a portable nuclear reactor.

(1960). An Investigation of Lens Opacity on Personnel Operating a Portable Nuclear Reactor. American Industrial Hygiene Association Journal: Vol. 21, No. 1, pp. 84-86.
FUNCTIONAL EFFECTS OF AMINO ACID SUBSTITUTIONS AT RESIDUE 33 OF HUMAN THYMIDYLATE SYNTHASE

Fluorinated pyrimidines, such as 5-fluorouracil (FUra) and 5-fluoro-2'-deoxyuridine (FdUrd), are cytotoxic to cells as a consequence of generation of 5-fluoro-2'-deoxyuridylate (FdUMP), which is a mechanism-based inhibitor of the enzyme thymidylate synthase (TS). FdUMP inhibits TS via its binding into a stable inhibitory ternary complex (ITC) with the enzyme and the cosubstrate N5, N10-methylene-5,6,7,8-tetrahydrofolate (CH2H4PteGlu). In previous studies, we identified a naturally occurring mutant form of human TS that contains a Tyr-->His substitution at residue 33 and confers relative resistance to FdUrd in both mammalian and bacterial cells. Kinetic studies indicated that the equilibrium dissociation constant (Kd) for binding of FdUMP into the ITC is altered in the mutant enzyme. In the current investigation, we have examined the kinetics of FdUMP binding into covalent binary complexes, i.e., in the absence of CH2H4PteGlu. Our results showed that although the rate constants for binary FdUMP binding (i.e., kon and koff) are altered by the Tyr-->His substitution, there is no measurable effect on the overall Kd. Analysis of a number of other amino acid substitutions at residue 33 indicated that maximal enzyme accumulation and function requires a bulky, hydrophobic side chain at this site.
Evaluating the Effects of tributyl phosphate (TBP) and normal paraffin hydrocarbon (NPH) in Simulated Low-Activity Waste Solution on Ion Exchange

Abstract Ultrafiltration and ion exchange are among the pretreatment processes selected for the Waste Treatment Plant at the U.S. Department of Energy's Hanford Site. Envelope B AZ‐101 waste may contain tributyl phosphate (TBP) and normal paraffin hydrocarbon (NPH)–dodecane, as dissolved species and also as a separate phase. This study is the second part of a two‐part study on Evaluating the Effects of TBP and NPH (dodecane) in Simulated Low‐Activity Waste Solution on Ultrafiltration and Ion Exchange. The first study dealt with ultrafiltration. The second part involved using filtrates from the ultrafiltration work to perform resin sorption experiments using SuperLig® 644 and SuperLig® 639 resins. SuperLig® 644 resin has a high selectivity for cesium, while SuperLig® 639 resin is highly selective for rhenium as perrhenate (the surrogate for pertechnetate). What is unknown is the effect the organics may have on these resins' high‐sorption capacities for cesium and rhenium. The goal of the study was to evalu...
The investigation of the type of active oxygen for the oxidation of propylene over bismuth molybdate catalysts using infrared and Raman spectroscopy

The investigation of the type of active oxygen for the oxidation of propylene over bismuth molybdate catalysts using infrared and Raman spectroscopy showed that in the ..cap alpha..-phase (Bi/sub 2/Mo/sub 3/O/sub 12/) only a few types of lattice oxygens, possibly bridged oxide ions, were involved in the reaction; in the ..beta..-phase (Bi/sub 2/Mo/sub 2/O/sub 9/) most, but not all types of lattice oxygen were involved; and in the ..gamma..-phase (Bi/sub 2/MoO/sub 6/) all lattice oxygens were involved. The tests were conducted with oxygen-18 labeled oxygen.
Fast feedback regulation of acth by cortisol

Abstract 1. Fast feedback regulation of ACTH by cortisol has not been well studied in humans. The authors studied the existence and characteristics of fast feedback regulation in normal humans. 2. Hydrocortisone hemisuccinate was infused at two different rates: 6 mg/hour and 12 mg/hour for two hours. 3. The studies did not demonstrate the existence of fast feedback regulation of basal ACTH concentration by cortisol in man. Further, the response was variable and the rate sensitive character was difficult to demonstrate.
R-wave amplitude change during aerobic exercise in hypertensive adolescents after treatment

This study attempts to determine whether the blunted reduction in R-wave amplitude during progressive aerobic exercise observed in adolescents with systemic hypertension could be altered by pharmacologic therapy to reduce blood pressure. Twenty-nine hypertensive adolescents were randomly assigned to treatment with either a diuretic, hydrochlorothiazide, or a centrally acting agent, clonidine. After 16 weeks of therapy, casual blood pressure was significantly reduced in both groups. Repeat exercise stress testing on therapy demonstrated a significant change in R-wave response. In both treatment groups the change in R-wave amplitude during exercise corresponded with the R-wave response pattern observed in normotensive control subjects. These observations indicate that the altered R-wave amplitude response to exercise observed in young hypertensive subjects is reversible and suggest that the altered R-wave response before treatment is related to a higher vascular resistance.
Turbulence effects on coherent laser radar target statistics

This paper reports theoretical probability density and cumulative distribution functions for glint and speckle target returns in a compact coherent laser radar. Calculator programs are given to facilitate use of these results.
DNA structures at chromosomal translocation sites

It has been unclear why certain defined DNA regions are consistently sites of chromosomal translocations. Some of these are simply sequences of recognition by endogenous recombination enzymes, but most are not. Recent progress indicates that some of the most common fragile sites in human neoplasm assume non-B DNA structures, namely deviations from the Watson-Crick helix. Because of the single strandedness within these non-B structures, they are vulnerable to structure-specific nucleases. Here we summarize these findings and integrate them with other recent data for non-B structures at sites of consistent constitutional chromosomal translocations.
Diffusion of Vitamin B12 Across a Mesoporous Metal Organic Framework

Abstract. We measure the rate of uptake and the rate of release of a Vitamin B12 solution (dissolved in water) at 2 different temperatures (room temperature and 37°C) by the mesoporous metal organic framework TbMOF-100 at 1-hour intervals using a spectrophotometer. Using the Beer-Lambert law, we calculate the concentration of the stock solution based on the absorbance values obtained with the spectrophotometer. These values allow for the quantification of the initial rate of uptake and the rate of uptake at a random incubation time of the Vitamin B12 by the TbMOF-100. We also calculate the value of the coefficient of diffusion for this 2-phase system using Fick’s laws of diffusion.
A new rheophytic species of Euceraea (Flacourtiaceae) from Sierra de la Neblina, Venezuela

Euceraea rheophytica is newly described and illustrated. It differs from the two other species in the genus, E. nitida and E. sleumeriana, in its much smaller and narrower leaves and in its smaller, spicate (vs. branched) inflorescences. It is known only from frequently flash-flooded riverbanks in the large, central canyon of the Sierra de la Neblina massif in southernmost Venezuela.
Intercombination lines of the zinc isoelectronic sequence for Z = 50-70.

The intercombination lines of the zinc sequence corresponding to the transition 4s4p ${}^{3}$${P}_{1}$\ensuremath{\rightarrow}4${s}^{2}$ ${}^{1}$${S}_{0}$ have been observed for xenon, lanthanum, neodymium, europium, gadolinium, and ytterbium in the Princeton Large Torus tokamak discharges.
Solid-State REDOR NMR Distance Measurements at the Ligand Site of a Bacterial Chemotaxis Membrane Receptor†

The Escherichia coli serine receptor senses serine levels in the environment and transmits this information across the bacterial inner membrane to modulate a protein phosphorylation cascade which controls swimming behavior. Solid-state nuclear magnetic resonance (NMR) has been used to characterize specific structural features of the ligand binding site interactions in the intact, membrane-bound Ser receptor. Rotational-echo double-resonance (REDOR) experiments on [15N]Ser bound to a [1-13C]Phe-receptor preparation are used to measure distances between the ligand amino group and the carbonyls of two phenylalanine residues in the ligand binding pocket. The results indicate two 4.0 ± 0.2 A distances, in excellent agreement with the X-ray crystal structure of a soluble fragment of the homologous aspartate receptor [Milburn et al. (1991) Science 254, 1342−1347]. These results confirm the similarity of the binding sites of the Asp and Ser receptors, and demonstrate the feasibility of using solid-state NMR measu...
Imaging the atomic surface structures of CeO2 nanoparticles.

Atomic surface structures of CeO2 nanoparticles are under debate owing to the lack of clear experimental determination of the oxygen atom positions. In this study, with oxygen atoms clearly observed using aberration-corrected high-resolution electron microscopy, we determined the atomic structures of the (100), (110), and (111) surfaces of CeO2 nanocubes. The predominantly exposed (100) surface has a mixture of Ce, O, and reduced CeO terminations, underscoring the complex structures of this polar surface that previously was often oversimplified. The (110) surface shows “sawtooth-like” (111) nanofacets and flat CeO2–x terminations with oxygen vacancies. The (111) surface has an O termination. These findings can be extended to the surfaces of differently shaped CeO2 nanoparticles and provide insight about face-selective catalysis.
Vanadyl binding to a testicular S-100-like protein and to calmodulin: Electron paramagnetic resonance spectra of VO2+-protein complexes

The binding of vanadyl to a porcine and bovine testicular S-100-like protein and to calmodulin was demonstrated using X-band (9.2 gHz) electron paramagnetic resonance (EPR) spectroscopy in aqueous solution at pH 7.4. In liquid solutions at 22°C, the vanadyl-protein complexes yielded VO2+ near rigid limit spectra. At 122 K, each of the three high-field resonances (i.e., 3/2, 5/2, and 7/2 parallel components) splits into two components indicating the presence of two classes of vanadyl-binding sites in each protein. The spectra of the frozen solutions were simulated to give parallel and perpendicular components of the hyperfine coupling constant and g factors similar to other vanadyl-protein complexes.
The Intersection of Homophobic Bullying and Racism in Adulthood: A Graduate School Experience.

The purpose of this article is to describe how homophobic bullying and bullying based on racism intersect in graduate school through the personal narrative of a gay Japanese male graduate student. First, I will provide a critical incident that demonstrates when, where, and how bullying based on homophobia and racism occurred in a specific graduate school environment based on personal journal entries. Second, I will analyze my personal bullying experiences. Last, I am going to point out what the fields of social services and higher education can offer to end bullying based on homophobia and racism.
Structure of the mouse myelin P2 protein gene.

: Myelin P2 protein is a small (14,800 Da) protein found in peripheral and central nervous system myelin. To investigate the regulation of expression of this myelin protein, a mouse genomic library was screened with a rabbit P2 cDNA (pSN2.2–2), and a single positive phage clone containing a 20-kb insert was obtained. This insert contained a single internal Sail restriction site and several EcoRI sites. The EcoRI fragments from this insert were subcloned into Bluescript. The rabbit P2 cDNA (pSN2.2–2) hybridized with a 4-kb EcoRI fragment, and this 4-kb fragment was then sequenced after the creation of nested deletions. The mouse gene contained four exons: exon 1 coded for amino acids 1–24, exon 2 for amino acids 24–81, exon 3 for amino acids 82–115, and exon 4 for amino acids 116–131. The three introns were 1.2 kb, 150 bp, and 1.3 kb in length. Primer extension analysis revealed two transcription start sites at +1 and +47, consistent with the presence of two P2mRNAs, with the larger transcript appearing more abundant. The amino acid sequences predicted from the mouse DNA indicate that the mouse protein differs from the rabbit protein at 16 different positions, with most of the differences located in exon 3. When the gene structure of fatty acid binding protein (FABP) genes were compared, the P2 gene had the same overall structure as others in the FABP family, suggesting a common ancestral gene for members of this family. The 5′-flanking region contains candidate TATA and CAAT sequences, as well as two AP-l binding sites that may be important in modulation of the expression of this gene.
Quarantine, Isolation, and Cohorting: From Cholera to Klebsiella

Abstract Background: Isolation is defined as the separation of persons with communicable diseases from those who are healthy. This public health practice, along with quarantine, is used to limit the transmission of infectious diseases and provides the foundation of current-day cohorting. Methods: Review of the pertinent English-language literature. Results: Mass isolation developed during the medieval Black Death outbreaks in order to protect ports from the transmission of epidemics. In the mid-1800s, infectious disease hospitals were opened. It now is clear that isolation and cohorting of patients and staff interrupts the transmission of disease. Over the next century, with the discovery of penicillin and vaccines against many infectious agents, the contagious disease hospitals began to close. Today, we find smaller outbreaks of microorganisms that have acquired substantial resistance to antimicrobial agents. In the resource-limited hospital, a dedicated area or region of a unit may suffice to separate a...