cssi/SciSciGPT-SciSciNet huggingface dataset:
Discovering relationships between service and customer satisfaction

Organizations spend significant resources tracking customer satisfaction and managing service delivery. Although a great deal of effort is expended in understanding what goes on within each of these areas, little or no effort has been applied to identifying and quantifying the relationships between the two. The objective of this research is to discover and establish potential relationships between service data and customer satisfaction. This understanding will enable more effective management, which will lead to improved quality, reduced cost and increased customer satisfaction. This study uses three years of data from an IBM operating system to measure the correlation between 15 service variables and nine customer satisfaction attributes. The results show that: (1) There is a relationship between the service data and customer satisfaction. This is the first time the existence of such a relationship has been proven and quantified. (2) The relative order of influence on customer satisfaction, of the four key service measures that are usually tracked, is defective fixes, followed by the number of problems, which in turn are followed by the number of defects and days-to-solution. The latter two were found to have little or no influence on customer satisfaction. (3) There is a return on investment of at least ten to one, for each dollar spent on quality improvement efforts in development.
The software engineering academy joins industry: results of the first annual international survey and a future portrait

According to data from an international survey, sponsored jointly by ACM/IEEE-CS, almost 8000 students are enrolled in software engineering degree programs in 11 countries, as of February, 2002. A total of 116 academic programs in software engineering is in place at 75 universities with 480 full-time faculty teaching hundreds of undergraduate and graduate courses in the discipline. Over 7000 people have obtained degrees in software engineering. These figures probably represent 40-50% of the total programs. The web-accessible report covers: history, audience, initial survey, initial results available, and "lessons learned". The sabbatical involved the initial development of an "International Software Engineering University Consortium" (ISEUC). The consortium is composed of a subset of 35 survey responders who use asynchronous distributed learning, and is slated to begin initial operations in September, 2002, based on the results of personal visits to Australia, Canada, the UK, and the USA. The primary markets are corporations that employ professionals trying to develop reliable, robust, and useful software products in a timely and efficient fashion, but who do not currently have state-of-the-art knowledge or skill.
Global Impact Of Tax Considerations For Displaced Workers

The current recession, combined with the globalization of the economy, outsourcing of jobs, and business downsizing, has resulted in thousands of workers experiencing the loss of their job. In addition to other circumstances that arise through the loss of a job, a new and unfamiliar set of tax issues can result through this new situation. This article will address some of the tax issues affecting displaced workers. The discussion will include strategies for displaced worker’s income, deductions, tax credits and special considerations.
Critical Professional Development: Centering the Social Justice Needs of Teachers

As a response to increasingly technocratic, top-down teacher professional development that we refer to as antidialogical professional development (APD), this article theorizes a model of critical professional development (CPD) where teachers are engaged as politically-aware individuals who have a stake in teaching and transforming society. Illuminating three US based case studies of CPD that emerged in response to the unmet needs of justice-oriented teachers- The People’s Education Movement, New York Collective of Radical Educators’ Inquiry to Action groups, and the Institute for Teachers of Color Committed to Racial Justice- this article uses Freire’s framework of dialogical action to analyze shared critical practices. In each independent case, teachers were engaged in a cooperative dialectical process, there was a strong emphasis on unity amongst participants around their social justice goals, the structure was organized through shared power between teachers and organizers, and teacher and student needs were centered using a practice of cultural synthesis. Reframing the possibilities of teacher professional development through this model of critical, dialogical practice, this article offers a critique of the banking methods and technical content traditionally used within APD, and provides insights into how teachers can successfully be positioned as experts in their own social justice-oriented professional growth.
With better adjuvant therapy, does breast cancer stage still matter?

Catching cancers when they are small still makes a difference to survival Breast cancer mortality is declining throughout the Western world.1 2 3 If, as J F Kennedy said, “victory has a thousand fathers,” then progress in breast cancer surely has a lot of parents. In the late 1970s, guidelines recommended screening mammography for women over the age of 40, resulting in implementation of national and regional screening programmes in most developed countries. Soon after, adjuvant endocrine therapy and chemotherapy were found to reduce the risk of breast cancer recurrence and death.4 5 Meanwhile, the combination of early detection and effective radiation therapy enabled breast conserving surgery as an option for most women.6 The implementation of these truly multidisciplinary treatment programmes, combining local and systemic treatments with public health screening initiatives and health awareness campaigns, revolutionised and improved breast cancer care. The linked paper by Saadatmand and colleagues brings that progress forward into the 21st century.1 Using a population based cohort of 173 797 patients and comparing patterns of care and outcomes in two time periods (1999-2005 v 2006-12), they document steadily improving survival for women with breast cancer in the Netherlands. Dutch …
Congenital transcobalamin II deficiency presenting atypically with a low serum cobalamin level: studies demonstrating the coexistence of a circulating transcobalamin I (R binder) complex

A case of transcobalamin II deficiency with several unique features is described. The clinical presentation was typical, except for a slightly delayed age at presentation and the occurrence of apparent neurologic dysfunction from the beginning. The unusual biochemical feature was a low serum cobalamin level (97 pg/ml). Several cobalamin-binding protein abnormalities coexisted and antedated cobalamin therapy. Chief among these was the complexing of all serum R binder (transcobalamin I), leaving the patient with no detectable R binder. This defect appeared to be transient. Noteworthy, too, was a prominent binder of 70,000 mol wt that also carried the bulk of his serum cobalamin after therapy; it was prominent in his presumably heterozygous relatives too. The interrelationship between all these abnormalities is intriguing but unclear. The abnormality in transcobalamin II deficiency is clearly not limited solely to deficiency of transcobalamin II. It is also evident that this entity must now be considered in the differential diagnosis of low serum cobalamin levels in infancy.
Incremental Cost-Effectiveness of 13-valent Pneumococcal Conjugate Vaccine for Adults Age 50 Years and Older in the United States.

BACKGROUND Recently released results from a randomized controlled trial have shown that 13-valent pneumococcal conjugate vaccine (PCV13) is efficacious against vaccine-type nonbacteremic pneumonia in adults.
Persistence of Aldrin and Heptachlor Residues on Alfalfa

Alfalfa was treated in 1956 with heptachlor and aldrin at the rates of ¼lb./acre and ⅛lb./acre, in order to study the disappearance of those insecticides under wisconsin conditions. Samples were collected immediately after treatment and 1, 3, 7, 14, and 21 days thereafter and were analyzed by specific chemical methods and by a direct feeding bioassay, using Drosophila melanogaster Meig. as a test insect. Seven days after treatment, both heptachlor and aldrin were recovered at a rate of 0.1 p.p.m., as tested by chemical analysis. However, when bioassays were conducted, the recoveries were slightly higher. In the case of aldrin, 7 days after treatment, 3.5 to 7.6 times more toxicant was recovered by bioassay as compared with results obtained by a specific chemical analysis. No heptachlor was found 2 weeks after treatment as tested by chemical and biological methods. No aldrin was found 3 weeks after treatment as tested by both methods.
Effects of Bacillus thuringiensis and HD-73 delta-endotoxin on growth, behavior, and fitness of susceptible and toxin-adapted strains of Heliothis virescens (Lepidoptera : Noctuidae)

A commercial formulation of Bacillus thuringiensis var. kurstaki Berliner (Dipel 2X) and purified HD-73 delta-endotoxin were evaluated for effects on the growth, behavior, and fitness of susceptible and toxin-adapted strains of Heliothis virescens (F.) by incorporation of the materials into artificial diets at varying concentrations. Neonate larvae were placed in experimental arenas where they could choose a diet containing toxin and a control diet, or were placed in arenas where the only diet available contained a toxin. The difference between the strains in growth and survival was much more pronounced when larvae could not choose to feed on the control diet. Both strains avoided moderate and high concentrations of the toxins. At the lowest concentration of HD-73, neither strain avoided the diet that contained the endotoxin. At the two lowest concentrations of Dipel 2X, only the susceptible strain avoided the diet containing Dipel. Data on growth rate, survival, and fecundity of the two strains reared on HD-73 delta-endotoxin were used to set parameters of a Single-locus genetic model to predict the rate at which H. virescens populations would adapt to B. thuringiensis var. kurstaki or its endotoxin when exposed to it in choice and no-choice situations. Results from the model generally predict much more rapid adaptation in no-choice situations.
Testing and Assessment for the Good of Education: Contributions of AERA Presidents, 1915–2015

Early presidents of the American Educational Research Association were leaders in the testing movement. Their intentions were to improve education by means of testing, which included both IQ and achievement tests. Early measurement experts acknowledged in scholarly articles that IQ tests could not measure inherited ability of groups with vastly different opportunities to learn, and yet ability testing was promoted as a beneficial means for matching instruction to individual differences until the insights of the civil rights era in the 1960s. Standard achievement measures were developed importantly to allow valid comparisons across school systems and over time, but the representations of learning that were adequate 100 years ago came to have distorting effects on teaching and learning. Today’s young psychometricians have opportunities to create new assessments in partnership with curriculum experts, but they should remain alert to the ways that well-intentioned assessment systems have been corrupted in the...
Children's Manifest Anxiety Scale: reliability with emotionally disturbed children.

The Children's Manifest Anxiety Scale is a brief questionnaire composed of 42 questions that can be answered by "yes" or "no" (1). It yields both a measure of anxiety and a measure of the child's tendency to deny common faults (L-scale). Despite interest in utilizing the test to discriminate levels of anxiety in emotionally disturbed children, there are few data available for such children. Before the test could be used as a measure of anxiety for such Ss, its reliability must be demonstrated. Thus, the purpose of the present study was to assess the test-retest reliability of this anxiety scale with 30 emotionally disturbed children (23 males, 7 females) in residential treatment. Their mean age was 11.07 yr., with a standard deviation of 2.00 yr. The test was individually administered to each S at the beginning and end of a 3-mo. period. The difference between mean raw scores on first and second administration did not differ significantly for the anxiety scale (MI = 22.33, SD, = 9.94; M2 = 23.67, SDa = 9.68; t = 1.10, p > .lo); the resulting correlation coefficient of .77 was significant (p .lo) and the resulting correlation of .80 was significant. Such results indicate that scores on the Children's Manifest Anxiety Scale were a reliable measure of anxiety over a 3-mo. period for these emotionally disturbed children. If the scale is also valid, then its research use with this population seems to be in order. Further work should be done to determine its validity and efficacy in differentiating levels of anxiety between normal and abnormal popularions. REFERENCE 1. CASTANEDA, A., MCCANDLESS, B. R., & PALERMO, D. S. The children's form of the Manifest Anxiety Scale. Child Deuelopmenr, 1956, 27, 316-317.
Effect of Ring Functionalization on the Reaction Temperature of Benzocyclobutene Thermoset Polymers

The temperature required to induce cross-linking in typical benzocyclobutene-based thermosets is near 250 °C, which exceeds the use temperature of many chemical components. A new and versatile synthesis of BCB-functionalized monomers has allowed access to monomers that can be incorporated into a variety of macromolecular platforms to enable significantly reduced cure temperatures. Incorporation of BCB-functionalized comonomers in polystyrene and polynorbornene enabled insolublization of thin films by curing at only 120 °C for 1 h.
Application of real-time fluorescent technique in the detection of duck Tembusu virus by reverse transcription loop-mediated isothermal amplification

Duck Tembusu virus(DTMUV) has caused huge losses to the poultry industry in China. A loop-mediated isothermal amplification(LAMP) assay based on real-time fluorescent technique was developed for the rapid detection of DTMUV using a set of specific primers according to the conserved region of DTMUV E gene. The sensitivity of real-time RT-LAMP was 100 times more sensitive than the conventional RT-PCR, with a detection limit of 7.8 copies. The specificity of real-time RT-LAMP was confirmed using RNAs and DNAs extracted from related viruses which caused duck infections. This method is specific and sensitive, and can quickly detect pathogen by observing the amplification curve. As a practical molecular diagnostic method, it can be used for rapid detection of DTMUV early infection and epidemiological investigation.
Characteristics of ore-controlling structures and prospecting significance in Guanfang Scheelite Deposit

The Guanfang Scheelite Deposit lies in Wenshan County,Yunnan Province,and is located at fold system in Southeastern Yunnan.It is a medium-large skarn-type scheelite deposit.In this paper,started from structures of ore field,structural characteristics of Guanfang Scheelite Deposit and its mechanism to take control of ore body are analyzed.The study indicates that the contact zone's structures of granite and wall rocks are important structural factors of mineralization.The extrusion and lifting environment is the foundation of mineralization.The contact zone's structures,F1 and F3 faults,Tuanshan fold in EW direction,interlayer cracks and interlayer fractured belt on wall rock common constitutes astructural system of mineralization.This research result will provide an important theory basis for mineralization rules and further prospecting in Guanfang Scheelite Deposit.
Introduction to Numerical Methods for Solving Differential Equations

After a brief presentation of the history of computing, and a discussion of the benefits of modeling and simulation, this chapter provides an overview of the key elements involved in the numerical solution of partial differential equations (PDEs). These include a broad (canonical) classification of the types of PDEs, the types of methods used to solve them, and the types of grid (or mesh) used to discretize PDEs in deterministic methods. A broad-level overview of the three most popular methods for deterministic solution of PDEs, namely the finite difference method, the finite volume method, and the finite element method is included. The chapter concludes with a discussion of the all-important topic of verification and validation of the computed solutions.
Up-regulation of cytokine mRNA in human monocytes and myeloid cell lines by the differentiation/activation factor p48

Polypeptide 48 is a 48,000 MW protein, originally isolated from conditioned media of some human leukaemic cell lines, that induces differentiation and cytolytic activity in HL-60 promyelocytic leukaemia cells and activates human peripheral blood monocytes to secrete interleukin-1 (IL-1) and tumour necrosis factor-alpha (TNF-alpha). In the present study we examined the effects of p48 on the accumulation of a series of monokine transcripts, including TNF-alpha, IL-1 alpha, IL-1 beta and IL-6, in human peripheral blood monocytes and the myeloid/monocyte cell lines HL-60 and U937. Using reverse transcriptase polymerase chain reaction (RT-PCR) and Northern blot analysis, p48 was found to induce accumulation of TNF-alpha, IL-1 alpha and IL-1 beta mRNA in peripheral blood monocytes, HL-60 and U937 cells. IL-6 mRNA was found to be increased in p48-stimulated peripheral blood monocytes but not HL-60 or U937. Thus, the secretion of IL-1 and TNF-alpha by p48-stimulated monocytic cells was associated with up-regulation of cytokine mRNA, suggesting that p48 leads to increased transcription or mRNA stability in these cells. As U937 and HL-60 are likely to represent premonocyte stages of haemopoietic differentiation, it is possible that the effect of p48 on IL-6 mRNA, in contrast to its effect on TNF and IL-1, requires cells to be at a later differentiation step.
Prediction of Biologically Active Epitopes for Synthetic Vaccines

ABSTRACT Synthetic peptides present a unique opportunity of making immunogens that are safe and effective. Locating biologically active epitopes on an organism is essential to developing synthetic vaccines. Methods of predicting biologically active epitopes are discussed.
Abstract 92: Approaches to Decision Support and Preparation for Destination Therapy Left Ventricular Assist Device: A Nationwide Sample of Mechanical Circulatory Support Coordinators

Background: Patients offered left ventricular assist device as destination therapy (DT LVAD) are typically faced with the decision to undergo major surgery and live their remaining life dependent on mechanical circulatory support (MCS) or transition to end-of-life care. MCS coordinators are often the first point of contact and provide education and support to patients making this difficult decision. Methods: We conducted semi-structured, in-depth interviews with MCS coordinators in order to characterize the range of decision support and preparation offered to patients considering DT LVAD and to solicit input on how to optimize that process. Interviews took place from August 2012 to January 2013. All interviews were digitally recorded and data were analyzed using a directed content analysis approach. Results: Our sample included 20 MCS coordinators from different programs around the United States. The following primary themes emerged: 1) cardiothoracic surgeons or heart failure cardiologists were primarily responsible for presenting risks and benefits of DT LVAD whereas coordinators provided the majority of patient education regarding practical concerns and patient/caregiver responsibilities; 2) existing consents and industry material are too complicated or overly optimistic; 3) tension exists between creating accurate expectations of DT LVADs and providing clinical reassurance - “I don’t want to scare them away from a life-saving therapy either, so I try to paint a realistic picture but not so realistic that it scares them;” and 4) when asked to theoretically consider if they were offered DT LVAD, the majority of coordinators stated that it would be a difficult decision influenced by their own age, co-morbidities, and family dynamics - “I think it would really depend on where I was in my life at that point in time.” Conclusions: MCS coordinators are in a unique position to assist in decision making and preparation for patients eligible for DT LVADs. In order to improve this process, a multidisciplinary and iterative approach appears helpful in conveying the risks and benefits of DT LVAD. Consents and educational materials must be simplified, patient-centered, and free of bias. Patient needs and values should be defined up front to help tailor the process. The uncertainty of many MCS coordinators, who arguably best understand the totality of therapy, to theoretically pursue DT LVAD themselves highlights the difficult trade-offs and personalized nature of this decision.
A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling.

Purpose: To assess the safety and tolerability of preoperative cryoablation-mediated tumor antigen presentation and/or ipilimumab-mediated immune modulation in women with operable breast cancer. Experimental Design: In this pilot study, 19 women with breast cancer for whom mastectomy was planned were treated with preoperative tumor cryoablation (n = 7), single-dose ipilimumab at 10 mg/kg (n = 6), or both (n = 6). The primary outcome for this pilot study was safety/tolerability as defined as freedom from delays in pre-planned, curative-intent mastectomy. Exploratory studies of immune activation were performed on peripheral blood and tumor. Results: Preoperative cryoablation and/or ipilimumab were safe and tolerable, with no delays in pre-planned surgery. Grade III toxicity was seen in 1 of 19 (unrelated rash after ipilimumab). Combination therapy was associated with sustained peripheral elevations in: Th1-type cytokines, activated (ICOS+) and proliferating (Ki67+) CD4+ and CD8+ T cells, and posttreatment proliferative T-effector cells relative to T-regulatory cells within tumor. Conclusions: Preoperative cryoablation and single-dose ipilimumab are safe alone or in combination with no surgical delays incurred. Potentially favorable intratumoral and systemic immunologic effects were observed with the combination, suggesting the possibility for induced and synergistic antitumor immunity with this strategy. Clin Cancer Res; 22(23); 5729–37. ©2016 AACR.
Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice.

ABSTRACT Disabled-2 (Dab2) is a clathrin and cargo binding endocytic adaptor protein, and cell biology studies revealed that Dab2 plays a role in cellular trafficking of a number of transmembrane receptors and signaling proteins. A PTB/PID domain located in the N-terminus of Dab2 binds the NPXY motif(s) present at the cytoplasmic tails of certain transmembrane proteins/receptors. The membrane receptors reported to bind directly to Dab2 include LDL receptor and its family members LRP1 and LRP2 (megalin), growth factor receptors EGFR and FGFR, and the cell adhesion receptor beta1 integrin. Dab2 also serves as an adaptor in signaling pathways. Particularly, Dab2 facilitates the endocytosis of the Ras activating Grb2/Sos1 signaling complex, controls its disassembly, and thereby regulates the Ras/MAPK signaling pathway. Cellular analyses have suggested several diverse functions for the widely expressed proteins, and Dab2 is also considered a tumor suppressor, as loss or reduced expression is found in several cancer types. Dab2 null mutant mice were generated and investigated to determine if the findings from cellular studies might be important and relevant in intact animals. Dab2 conditional knockout mice mediated through a Sox2-Cre transgene have no obvious developmental defects and have a normal life span despite that the Dab2 protein is essentially absent in the mutant mice. The conditional knockout mice were grossly normal, though more recent investigation of the Dab2-deficient mice revealed several phenotypes, which can be accounted for by several previously suggested mechanisms. The studies of mutant mice established that Dab2 plays multiple physiological roles through its endocytic functions and modulation of signal pathways.
Unifying the Study of Asymmetric Hypotheses

This article presents a conceptual clarification of asymmetric hypotheses and a discussion of methodologies available to test them. Despite the existence of a litany of theories that posit asymmetric hypotheses, most empirical studies fail to capture their core insight: boundaries separating zones of data from areas that lack data are substantively interesting. We discuss existing set-theoretic and large-N approaches to the study of asymmetric hypotheses, introduce new ones from the literatures on stochastic frontier and data envelopment analysis, evaluate their relative merits, and give three examples of how asymmetric hypotheses can be studied with this suite of tools.
Rotator Cuff Repair in Adolescent Athletes

Background:Rotator cuff tears are rare injuries in adolescents but cause significant morbidity if unrecognized. Previous literature on rotator cuff repairs in adolescents is limited to small case series, with few data to guide treatment.Hypothesis:Adolescent patients would have excellent functional outcome scores and return to the same level of sports participation after rotator cuff repair but would have some difficulty with returning to overhead sports.Study Design:Case series; Level of evidence 4.Methods:A retrospective search of the practice’s billing records identified all patients participating in at least 1 sport who underwent rotator cuff repair between 2006 and 2014 with an age <18 years at the time of surgery and a minimum follow-up of 2 years. Clinical records were evaluated for demographic information, and telephone follow-up was obtained regarding return to play, performance, other surgery and complications, a numeric pain rating scale (0-10) for current shoulder pain, American Shoulder and E...
Signal sets for constellation expansion in NOMA

In this paper, alternative signal set designs for higher order constellations based on combinatorial structures are proposed. These system designs are practical for 5th and future generation of systems. Non-Orthogonal Multiple Access (NOMA) is currently recognized as a promising multi-access technique for fifth generation (5G) networks. NOMA techniques ensure that multiple users share the same spectrum or resource. Sharing the same resource by multiple users results in interference and an expansion in the received constellation. This expansion is driven by the number of users transmitting and the constellation for each user. Solutions for these expansions involved rotations of transmit user's constellations, lattice decoding, transmission at orthogonal frequencies with different phases and other solutions. The proposed system, using a non-orthogonal combinatorial structure provides a large signal set that is distinguishable at the receiver. Using a non-orthogonal format, a solution is proposed where large number of users share the channel. Performance is evaluated using upper bounds for their error probability considering the interference between users.
Reasoning with Cognitive Structures of Agents I: Acquisition of Rules for Computational Theory of Perceptions by Fuzzy Relational Methods

Generalized fuzzy rules provide the essential means for computational representation of equational and inequality constraints over fuzzy granular structures. In this chapter, we are concerned with the ways the rules can be acquired from the real world data. We also provide a method for elicitation of knowledge of experts and link this to Zadeh’s Computational Theory of Perceptions. The algorithms for extracting and consistency checking of the rules explore the BK-products of relations. This makes it possible to treat the numerical and linguistic computations in a unified framework with the methods for extrapolation of knowledge and data.
Ultra-sensitive diatomite microfluidic devices for hazardous chemical sensing (Conference Presentation)

The escalating research interests in porous media microfluidics, such as microfluidic paper-based analytical devices (μPADs), have fostered a new spectrum of microfluidic devices for point-of-care diagnosis and biosensing. In this paper, we report diatomite microfluidic devices, which consist of multi-scale hierarchically porous photonic crystal biosilica channels, as an innovative lab-on-a-chip platform to detect hazardous chemicals. The diatomite microfluidic devices in this work are fabricated by simple spin-coating and tape-stripping diatomaceous earth on regular glass slides with cross section of 400×30μm2. As the most unique feature, our diatomite microfluidic devices can simultaneously perform on-chip chromatography to separate small molecules from complex samples and acquire the surface-enhanced Raman scattering spectra of the target chemicals with high specificity. Owing to the ultra-small dimension of the diatomite microfluidic channels and the photonic crystal effect from the fossilized diatom frustules, we demonstrate unprecedented sensitivity down to ppb-level when detecting pyrene (1ppb) from mixed sample with Raman dye and cocaine (10ppb) from human plasma. This pioneering work proves the exclusive advantage of diatomite microfluidic devices as emerging microfluidic devices for chemical and biomedical sensing.
Economía del comportamiento: pasado, presente y futuro*

“Behavioral economics” attempts to incorporate insights from other social sciences, especially psychology, in order to enrich the standard economic model. The interest in the psychology of human behavior returns economics to its earliest roots. Adam Smith talked about such key concepts as loss aversion, overconfidence, and self-control. Nevertheless, the modern version of behavioral economics introduced in the 1980s met with resistance by some economists, who preferred to retain the standard neo-classical model. They introduced several arguments for why psychology could safely be ignored. In this essay I show that these arguments have been rejected, both theoretically and empirically, so it is time to move on. The new approach should include two different kinds of theories: normative models that characterize the optimal solution to specific problems and descriptive models that capture how humans actually behave. The latter theories will incorporate some variables I call supposedly irrelevant factors, which can improve the explanatory power of economic models.
The Peak in Africa (September 2014)

By September 2014, the Ebola outbreak had overwhelmed West African healthcare systems. Treatment centers were filled beyond capacity and new centers could not be opened fast enough to deal with the increasing number of cases. Overflowing medical facilities had to turn away newly arriving infected patients. Heartbreaking scenes occurred as sick patients crisscrossed cities looking for space in treatment centers only to find that no space was available. As conditions worsened, Sierra Leone took the unprecedented step of holding a 3-day, nationwide lockdown. During the lockdown, healthcare workers visited every house in the country. They gave residents information about Ebola and looked for new cases. Levels of foreign aid remained relatively low, but efforts were beginning to ramp up. In the middle of September, the United States launched a major Ebola offensive and began to send military personnel to Liberia. On the very last day of the month, news broke that an active Ebola case had been detected in Dallas, Texas. Ebola had left Africa and arrived in a western country.
Modeling the cybersecurity of hospitals in natural and man-made hazards

Hospital cybersecurity has become a growing concern with an increasing number of cyberattacks against hospitals and health care facilities. We aim to tackle this issue by developing a model to capt...
Displacement of an uncemented femoral component after dislocation of a total hip replacement. A case report.

A case is presented of a patient in whom the femoral component displaced during the attempted closed reduction of a dislocation of the total hip replacement four weeks after its insertion
Membrane-mediated synthesis of tissue factor (thromboplastin) in cultured fibroblasts.

A potent procoagulant synthesized by cultured human skin fibroblasts has been identified as tissue factor (factor III, thromboplastin), since it binds factor VII and is blocked by a specific antitissue factor antibody. Fibroblast tissue factor is, at least in part, a labile superficial, membrane-associated substance the synthesis of which is mediated by cell adhesion but is inhibited by actinomycin-D and puromycin. Tissue factor production is related to the shape change that occurs as the cells spread on the floor of the culture vessel, but tissue factor is not synonymous with the configuration on the cell surface responsible for cell adhesion. These observations suggest that cell membranes may play a significant role in hemostasis and thrombosis by virtue of their tissue factor content.
CELL DIVISION AND GROWTH STUDIES ON SYNCHRONIZED FLAGELLATES1

Publisher Summary This chapter presents an overview of cell division and growth studies on synchronized flagellates. The synchronization of the flagellate A. longa on a diurnal temperature cycle of 6.5 h at 28.5°C and 17.5 h at 14.5°C yields cultures in which all the cells divide in a burst of 2.8 h duration. The dilution of the culture with new medium once each cycle at the beginning of the cold period gives a type of continuous culture in which there appears to be a selection for cells dividing on schedule. A 100% change of O2 consumption occurs at the time of division burst, while at the same time, there is only a 66% change in the dry weight.
Influence of Environmental Stress on the Kinetics and Strength of Attachment of Listeria monocytogenes Scott A to Buna-N Rubber and Stainless Steel

Attachment and detachment of Listeria monocytogenes Scott A to Buna-N rubber and stainless steel under varying conditions of temperature and pH were investigated using model systems. Numbers of attached cells increased with increasing attachment temperature (10 to 45 degrees C) and time (up to 120 min) for both test surfaces. Compared to Buna-N rubber, the rate of attachment to stainless steel was markedly more rapid for all temperature and pH conditions studied and could not be calculated. Rate of attachment to Buna-N rubber was found to be significantly lower when cells were attached at 10 degrees C. Growth temperature did not significantly affect rates of adhesion to Buna-N rubber. Altering the medium pH during attachment between 4 and 9 demonstrated that rates of adhesion were slower under alkaline conditions. Growth pH was also found to significantly affect rates of attachment to Buna-N rubber. Detachment of cells adhered to Buna-N rubber was significantly affected by growth temperature but not growth pH. Significant differences in detachment were also found between Buna-N rubber and stainless steel, inferring stronger attachment to Buna-N rubber. Cell surface hydrophobicity was found to be affected by both growth temperature and growth pH. However, changes in hydrophobicity could not be correlated to differences in rates of attachment. Addition of 0.01% trypsin to the attachment medium during cell exposure to either test surface resulted in a 99.9% reduction in the adhered cell population when compared to controls. This would suggest that proteins play a role in the initial attachment process of L. monocytogenes.
Beam Profiler for Single-Photon Applications based on Compressive Sampling Techniques

We report the development of a low-cost beam characterization technique appropriate for extremely low light levels. The technique makes use of compressive sampling strategies that have been developed recently for imaging applications.
Regulation of Cell Wall Thickening by a Medley of Mechanisms

To provide physical support for developing structures and to withstand the pressures associated with water and nutrient transport, some cells deposit a secondary cell wall, a rigid matrix of polysaccharide and phenolic biopolymers. The biosynthesis and deposition of these materials and the patterning of secondary wall-forming cells is controlled by a network of transcription factors. However, recent work suggests that this network forms the core of a more complex, multilevel regulatory system. This expanded system includes epigenetic, post-transcriptional, and post-translational regulation, and is coordinated with other pathways controlling primary growth and responses to environmental stimuli. New findings expand the set of transcription factors identified as secondary cell wall regulators and reveal novel regulatory processes that further govern secondary wall biogenesis.
Critical Review of Measurement Practices in the Study of Automatic Associations of Sedentary Behavior, Physical Activity, and Exercise.

Studies of automatic associations of sedentary behavior, physical activity, and exercise are proliferating, but the lack of information on the psychometric properties of relevant measures is a potential impediment to progress. The purpose of this review was to critically summarize measurement practices in studies examining automatic associations related to sedentary behavior, physical activity, and exercise. Of 37 studies, 27 (73%) did not include a justification for the measure chosen to assess automatic associations. Additional problems have been noted, including the nonreporting of psychometric information (validity, internal consistency, test-retest reliability) and the lack of standardization of procedures (e.g., number, type of stimuli). The authors emphasize the need to select measures based on conceptual arguments and psychometric evidence and to standardize measurement procedures. To facilitate progress, the review concludes with a proposal for conceptually appropriate validation criteria to be used in future studies.
Personality‐cognition associations across the adult life span and potential moderators: Results from two cohorts

Objective Personality and cognitive abilities have been previously linked. However, there are inconsistencies regarding whether this relationship varies as a function of age, and a lack of evidence on whether gender contributes to this relation, particularly across the adulthood. Therefore, this study investigated the association between personality and cognition across the adult life span, accounting for age and gender. Methods We examined the association between personality and cognition in two large samples (Sample 1: N = 422; Sample 2: N = 549) including young, middle-aged and older adults. Participants completed personality scales and several cognitive measures related to reasoning, language, memory and speed of processing. Structural equation modeling was applied in order to investigate associations between personality and cognition, and moderation of age and gender within this relationship. We also conducted a mini-meta-analysis procedure in order to examine personality-cognition associations, combining results from the two samples. Results Openness was the main trait associated with cognitive performance; however, Extraversion, Conscientiousness, and Neuroticism were also independently associated with cognition. Age and gender did not consistently moderate personality-cognition in each sample, but the mini-metanalysis showed that gender moderated Conscientiousness-cognition associations. Conclusions We provided robust evidence of personality-cognition associations across the adult life span, which was not consistently moderated by age, but in part by gender.
Altered endothelial ETB receptor expression in postmenopausal women

Our study provides novel data demonstrating attenuated endothelial ETBR expression in postmenopausal women. Furthermore, our data extend current knowledge by demonstrating a positive relation betwe...
Stress Testing and Cardiopulmonary Exercise Testing

Cardiovascular health and fitness requires coordinated function of the heart and circulatory system with a primary goal of providing ample energy substrate to organs and skeletal muscle. Under resting condition, the body’s metabolic requirement and corollary demands on the cardiovascular system are modest. In contrast, physical activities ranging from the simple tasks of daily living to vigorous forms of physical exertion require marked increases in metabolism and thus increased substrate delivery by the cardiovascular system. On a nearly instantaneous basis, the cardiovascular system adjusts function, commonly measured by cardiac output, to meet the body’s demand. An inability to rapidly and completely meet this demand caused by dysfunction of the heart or blood vessels leads to key manifestations of common forms of cardiovascular disease including chest pain, exertional dyspnea, and exercise intolerance. The cardiovascular system’s ability to meet the metabolic demands of the body can be assessed using exercise or “stress” testing. This chapter will provide an overview of clinical stress testing with an emphasis on basic clinical exercise physiology, exercise and pharmacologic stress testing modalities, and the use of adjunct diagnostic modalities including cardiac imaging and metabolic gas exchange.
Effects of Comprehensive‐Income Characteristics on Nonprofessional Investors' Judgments: The Role of Financial‐Statement Presentation Format

Statement of Financial Accounting Standards (SFAS) No. 130 requires companies to report comprehensive income in a primary financial statement, but allows its presentation in either a statement of comprehensive income or a statement of stockholders' equity (Financial Accounting Standards Board [FASB] 1997). In an experiment, we examine whether and how alternative presentation formats affect nonprofessional investors' processing of comprehensive‐income information, specifically, information disclosing the volatility of unrealized gains on available‐for‐sale marketable securities. The results show that nonprofessional investors' judgments of corporate and management performance reflect the volatility of comprehensive income only when it is presented in a statement of comprehensive income. We provide evidence consistent with our psychology‐based framework that these findings occur because format affects how nonprofessional investors weight comprehensive‐income information and not whether they acquire this inf...
Sensitivity to Psychologically Coercive Interrogations: A Comparison of Instructions and Expert Testimony to Improve Juror Decision-Making

Confession evidence is powerful to jurors, even when obtained using psychologically coercive means. To assist jurors in evaluating confession evidence, courts may provide instructions or expert tes...
Paying for College and Teaching Your Peers: An Approach for Deeper Learning

This paper reports on a project that investigate the impact of a near-peer teaching intervention on undergraduate students’ understanding of student loans and college expenses. The research is a pilot study based on a small sample size of undergraduate students. The sample consists of the 38 students enrolled in an undergraduate personal finance course at The Ohio State University in Spring 2019. Students completed a two-workshop, near-peer teaching project at a local high school on the topic of “costs of college”. Follow-up survey responses document the effectiveness of the project for the undergraduate students’ learning of key personal finance topics and of useful professional skills.
Parasitic Inductances Extraction for SiC Power Modules Using An Enhanced Two-Port S-Parameter Approach

Parasitic inductance of power modules is one nonnegligible part of inductance on converters’ current commutation loop (CCL). Larger CCL inductance leads to higher switching oscillation, voltage overshoot, electromagnetic interference (EMI), and larger power losses. This paper uses two-port scattering (S) parameter measurement to extract the parasitic inductance of the power module. The innovation of this paper is that it considered the impact of mutual inductance and fixture printed circuit board (PCB) when using S-parameter approach. Accurate internal parasitic inductance values can be obtained by logic analysis, no matter used in a traditional two-level (2-L) inverter or three-level (3-L) T-type inverter. And it provides the guidance to build the fixture PCB board to connecting vector network analyzer (VNA) and the module, which has not been discussed in the existing literature. The approach is experimentally validated by a commercial 1200V SiC half-bridge power module.
The Asian currency crisis : origins, lessons, and future outlook

What started in the summer of 1997 as a regional economic and financial crisis in East and Southeast Asia had developed into a global financial crisis within the span of a year. This crisis followed the crisis in the European Monetary System in 1992-3 and
Recruiting RCT Participants: To Facebook or Not to Facebook?

Little is known about how best to capture the interest of potential study participants using Facebook (FB) ads. Thus, the effectiveness of 64 FB recruitment ads for HomeStyles, a nutrition interven...
Studies on peptides. CLXVII. Solid-phase syntheses and immunological properties of fragment peptides related to human malaria circumsporozoite protein.

A glycine-linked tetramer of Asn-Ala-Asn-Pro, a tandem repeated sequence of malaria circumsporozoite (CS) protein, was synthesized by the Boc-based solid phase method, followed by deprotection with 1 M trimethylsilyl trifluotomethanesulfonate-thioanisole in trifluoroacetic acid. In addition, three tetramer-related peptides were similarly synthesized, i. e., a 34-residue peptide [linked with TH, a proposed T-cell epitope of CS, at the C-terminus of the tetramer], a 46-residue peptide and a 59-residue peptide [linked with HA or HA', two preposed T-cell epitopes of influenza hemagglutinin protein, at the N-terminus of the above 34-residue peptide]. Their immunological properties were examined by enzyme-linked immunosorbent assay, for which three different congenic strains of mouse were used to raise the specific antibodies. Despite conjugation of T-cell epitopes to the tetramer, the mice of low-responder strains to the tetramer failed to produce any antibody specific to the tetramer. However, with the aid of recombinant interleukin 2 as an adjuvant, the low-responder mice produced antibody with relatively high titers.