cssi/SciSciGPT-SciSciNet huggingface dataset:
Swinger, Bi, Trans, Zoo, S&M—Just Not Old!1 Sexual Charity in the Novels of Michel Houellebecq

ABSTRACTThis article examines issues of sexual inequality, charity, and utopia in the novels of Michel Houellebecq and situates them within similar discourses in the French tradition, notably within the works of Fourier, de la Bretonne, and de Sade. I trace a genealogy in French thinking about sexual inequality and utopia and note its recent expression in Houellebecq’s novels, arguing that Houellebecq’s work calls attention to the problem of arbitrary embodiment.
Transportation of pediatric femur fractures to a tertiary care center: a retrospective review.

Introduction Pediatric femur fractures are common injuries presenting to tertiary care trauma centers. Transportation of these patients occurs most commonly via ambulance or flight. The purpose of this study is to evaluate whether mode of transportation affects time to surgery or hospital stay for pediatric patients with femur fractures. Methods Utilizing a trauma registry we queried pediatric femur fractures between January 2001 and December 2009. Patient age, gender, mechanism of injury, month of injury, type of fracture, transportation, county of origin, time to operating room (TTOR), hospital length of stay (HLOS), and treatment received were identified and compared. Results In total, 519 femur fractures were identified, 257 (49.5%) of which were isolated injuries. Flight transportation was utilized in 13.6 % (35 of 257) of these isolated fractures. Mean TTOR for flight patients was 29 hours, HLOS 3.2 days. For ambulance transportation mean TTOR was 41 hours, HLOS 3.2 days. Neither variable was statistically different between transportation groups (TTOR p > 0.50; HLOS p > 0.95). No statistical difference was seen in HLOS (p > 0.47) and TTOR (p > 0.71) for patients originating further distances from the hospital. Conclusion Transportation method and distance from the hospital did not affect the TTOR and HLOS for isolated pediatric femur fractures. The use of air transportation for this group of patients, many of whom are injured by relatively low energy mechanisms, may be excessively costly and does not accelerate treatment.
Individual and Group Differences in Nonverbal Behavior

The purpose of the present chapter is to discuss some of the major factors affecting the role of nonverbal behaviors in social interaction. That is, while our intention in this volume is to try to discover and analyze the regularities in the social use of nonverbal behavior, we are all too aware of the limitations in generalizing these patterns across different circumstances. Another way of describing this concern is to appreciate that a number of factors interact with or moderate the patterns of nonverbal behavior discernible in various social processes. While the potential list of individual-difference variables could include a variety of different factors, this treatment will center on just three of them—culture, sex, and personality. Other factors such as age, socioeconomic status, or even occupation and religion may very well influence an individual’s nonverbal expression, but culture, sex, and personality seem to be more important and consistent in their effect.
The Master Switch: The Rise and Fall of Information Empires by Tim Wu New York: Alfred A. Knopf, 2010, 366 pp

(2011). The Master Switch: The Rise and Fall of Information Empires by Tim Wu New York: Alfred A. Knopf, 2010, 366 pp. American Journalism: Vol. 28, No. 2, pp. 159-161.
Emerging Engineering Strategies for Studying the Stem Cell Niche

Stem cell niches are discrete anatomical microenvironments that present a rich collection of extrinsic factors to govern stem cell behavior. In particular, these niche signals—including soluble cues, extracellular matrix (ECM)-associated signals, and cues from neighboring cell types—play key roles in balancing stem cell self-renewal and differentiation. Recapitulating fundamental features of the stem cell niche in vitro to investigate regulatory mechanisms has proved to be a challenging, yet necessary, task for dissecting the regulatory role of stem cell niches and for developing stem cell-based therapies. However, the recent emergence of innovative engineering strategies has enabled the development of model platforms that have yielded key insights into niche-directed stem cell behavior. As such control mechanisms of the stem cell niche are elucidated, engineering strategies have evolved concurrently to facilitate the study of more complex phenomena. In this review, we highlight the progression of these emerging engineering strategies, focusing on the growing emphases on spatiotemporal control and single-cell studies for examining stem cell-ECM interactions and the effects of heterotypic cellular interactions, respectively.
Bioengineering of Crops

The primary objectives of the World Bank’s international program are the alleviation of poverty, malnutrition and human misery in developing nations while encouraging and supporting a transition to environmentally sustainable activities. The issue of providing adequate food, based on sustainable agricultural practices, looms large in gaining these objectives, for failure in this area virtually guarantees failure to meet other objectives. It would make certain continued misery for many of our fellow human beings. Agricultural systems are already under stress and will become more so as populations continue to swell and the need for increased food supplies swells with them.
Phosphorylation affects the mobility of the E1 α-subunit of branched-chain 2-oxo acid dehydrogenase on sodium dodecyl sulphate/polyacrylamide-gel electrophoresis

heat-stable protein kinse inhibitor (50 units/ml), therefore ruling out the possibility that the protein kinase represents the free catalytic subunit of cyclic AMP-dependent protein kinase. Heparin, at a concentration of IOpg/ml, which inhibits the phosphorylation of acetyl-CoA carboxylase by casein kinase I and I1 (Tipper et al., 1983; Munday & Hardie, 1984) also had no effect on the phosphorylation reaction. The activity of acetyl-CoA carboxylase decreased dramatically in parallel with the phosphorylation by the protein kinase. At a subsaturating concentration ( 0 . 5 m ~ ) of the allosteric activator, citrate, the activity of acetyl-CoA carboxylase decreases from 0.54 pmol/min per mg to 0.03 pmol/min per mg, while at IOrnM-citrate (a saturating concentration) the acetyl-CoA carboxylase activity decreases from 2pmol/min per mg to 0.45 pmol/min per mg (Fig. 1). Rapid reversal of the phosphorylation and inhibition of acetyl-CoA carboxylase is achieved by the addition of the partially purified catalytic subunit of protein phosphatase2A (not shown). The physiological importance of this protein kinase in the control of hepatic lipogenesis is currently being investigated. It will be of interest to determine whether the protein kinase we have isolated can account for the high basal phosphorylation and low activity of acetyl-CoA carboxylase that is observed when the enzyme is isolated from rat liver in the presence of sodium fluoride (Holland e t al., 1984).
Absorption Coefficient Measurements of Carbonaceous- Based Aerosol Particles Using a Laser-Driven Thermal Reactor

The absorption coefficient of carbonaceous-based substances was determined using a novel approach of rapid and controlled heating with laser radiation. The approach analyzes the unsteady thermal behavior and decomposition of these substances. Results were obtained for clean quartz filters, for filters contaminated with laboratory air particles and combustion-generated soot, and for disk- and sphere-shaped activated carbon pellets at different sample temperatures, inert gas environments, and gas pressures. The absorption coefficient, in general, decreased with steady- state sample temperature, except for the carbon spheres. It was also found that the gas environment and pressure had negligible effect on the sample absorptivity, but substance shape and mass played an important role in determination of the absorption coefficient.
U.S. Actions to Reduce Emissions of Non-CO2 Gases

The US has taken aggressive steps to reduce emissions of non-CO2 greenhouse gases (NCGG) using a number of policy approaches. The US may be unique in the world in the scope of its NCGG programs, which address emissions of methane and the high-GWP gases. For the most part, US programs are voluntary in nature. There are some regulatory programs, however, aimed at reducing emissions of other pollutants and having the side benefit of reducing greenhouse gas emissions as well. This paper describes US programs to reduce NCGG emissions. Information is provided on the strategic approach of these programs, their development and structure, and results to date. In addition, key lessons learned based on US experience are presented.
Paraneoplastic syndromes and the nervous system.

a paraneoplastic syndrome but is antibody-nega-tive, investigation should focus on other serologic markers of cancer, including carcinoembryonic antigen, cancer antigen (CA)-125, CA-15-3, and prostate speciﬁc antigen.Aggressive search for the suspected cancer should include serum immunoelectrophoresis; skeletal survey; computerized tomography of the chest, abdomen, and pelvis; testicular ultrasonog-raphy; magnetic resonance imaging; and positron emission tomography (PET) scanning with the glucose analog 2-
Abstract A43: Long noncoding RNAs as targets of mammary tumor cell proliferation and migration

Objective: Recent genome-wide studies revealed that as much as 80% of the human genome can be transcribed whereas only 2% of this RNA is translated into proteins. Non-coding transcripts can be subdivided into several groups, with long non-coding RNAs (lncRNAs) representing the largest and most diverse class. With breast cancer being the most frequent malignancy in women worldwide, we set out to investigate the potential of lncRNAs as novel therapeutic targets. Methods: We focused on the luminal B and the HER2/neu-positive subtypes of breast cancer, as both are associated with high prevalence and bad prognosis. By performing RNA-Seq on tumor sections and mammary organoids from MMTV-PyMT and MMTV-Neu-NDL mice, modeling the luminal B and HER2/neu-amplified subtypes of human breast cancer respectively, we generated a comprehensive catalog of differentially expressed lncRNAs. We functionally validated the role of a subset of these lncRNAs by antisense oligonucleotide (ASO) mediated knockdown in primary mammary tumor cells and 3D ex vivo organoids. Results: We identified several hundred potentially oncogenic lncRNAs that were over-expressed in a subtype-specific manner as well as numerous lncRNAs up-regulated in both MMTV-PyMT and MMTV-Neu-NDL tumors. To narrow down the candidate list of lncRNAs with the highest therapeutic potential, we sorted the data computationally and defined a subset of previously uncharacterized lncRNAs as Mammary Tumor Associated RNAs (MaTARs). Upon independent knockdown of several MaTARs, we observed significantly reduced cell proliferation, invasion and/or collective cell migration in a cancer-specific context. Conclusion: MaTARs are likely important drivers of mammary tumor progression and/or metastasis and represent promising new therapeutic targets. Future studies will focus on the molecular characterization of these lncRNAs and elucidation of their potential role(s) in mammary tumor progression and metastasis.
Effects of an angiotensin converting enzyme inhibitor on psychosocial hypertension in mice.

1. Renin-associated, chronic psychosocial hypertension of 150–160 mmHg develops in groups of mice interacting socially in complex population cages. 2. The blood pressures of 16 males in a cage were measured and an intraperitoneal injection of the angiotensin coverting enzyme inhibitor captopril (SQ 14 225) was given. Three hours later blood pressures were measured again. 3. During the first 3 weeks of psychosocial hypertension SQ 14 225 was without effect. But at 1 month and subsequently up to 7 months, SQ 14 225 reduced blood pressure to the normal range of 120–130 mmHg. 4. Plasma renin activities were not related to the extent of blood pressure reduction by SQ 14 225. Hence other factors in addition to the renin—angiotensin mechanism play a part in maintaining chronic psychosocial hypertension.
The Political Economy of Kurdish Nationalism

We have discussed at some length the changes that led to the disintegration of the tribal type ‘face-to-face’ society in Chapter 2. Much of the Kurdish population was absorbed into the settled population of villages whose economic life was no longer dependent merely on herding, but also significantly on agriculture. The latter type of communities were also ‘face-to-face’ societies but of a village type. It may appear that all that happened was that one type of ‘face-to-face’ society was replaced by another without bringing about the sort of change in the mentality of the rural population required of them before they can see themselves as a homogenous national community.
Traveling-wave microwave switch using III-N gateless devices with capacitively-coupled contacts

Radio-frequency (RF) switches using Field-Effect Transistors (FETs) have low loss, high switching speed. The fabrication process allows for monolithic integration with such as power amplifiers, phase shifters, arrays, and other components. Recent advancements in III-nitride heterostructure field-effect transistors (HFET) have led to RF switches with remarkably low-loss and high power handling capability, ideal for numerous applications [1, 2]. However, relatively large OFF-state capacitance of HFETs limits their application to frequencies below 4–6 GHz. In the past, traveling-wave (TW) RF switches using GaAs-based HFETs have been reported with operating frequencies up to 40–80 GHz [3]. The achieved insertion loss and isolation were below 3 dB and above 24 dB, correspondingly. The problem with GaAs-based TW switches is that for broadband performance, the switch should contain significant number (at least 10) of unit cells, each comprising multi-finger FETs. To make this technology feasible, either relatively small number of cell is used, or the unit cell periphery is decreased, or the source — drain distance is increased. All these measures deteriorate the performance. In addition, GaAs-based RF switches have relatively low power handling capability, high insertion loss and low maximum operating temperatures limited by fundamental material properties.
“Stand by Me”: A Mixed Methods Study of a Collegiate Marching Band Members’ Intragroup Beliefs Throughout a Performance Season:

The purpose of this mixed methods study was to investigate intragroup beliefs regarding participation in a National Collegiate Athletic Association (NCAA) Division II marching band throughout the u...
Predicting dose sparing benefit and bleeding risk of pharmacokinetic-based personalized prophylactic dosing of factor VIII products

Background Previously published factor VIII (FVIII) pharmacokinetic (PK)-based dosing approaches employ fixed infusion interval with a wide dose range that may lead to increased risk of bleeding, excessive doses or decreased health-related quality of life. Aim The objectives of the study includes (i) personalizing infusion interval in lieu of fixed infusion, (ii) constraining dose within the range of 10-50 IU/kg and (iii) characterizing bleeding risk of PK-based dosing in comparison with empiric standard doses. Methods Patient demographics and PK parameters for conventional FVIII products were obtained from published literatures. Subject-specific PK parameters were derived from FVIII activities vs time data generated through simulation. Results Our data indicated approximately 4%, 38%, 37% and 20% of the subjects can be dosed with infusion interval of every 24, 48, 72 and 96 hours, respectively, for maintaining a target 1 IU/dL FVIII level within the dose range of 10-50 IU/kg. Maintaining an alternative trough value of 3 or 5 IU/dL requires more frequent infusion. The predicted median probability of bleeding risk per year was 35.7% (range, 11%-49%) for PK-based dosing maintaining 1 IU/dL. Predicted median bleeding risk was 37.9% (0%-74%), 32.8% (0%-72%) and 26.7% (0%-70%) for standard dosing of 20, 30 and 50 IU/kg, respectively. PK-based dosing resulted in a dose sparing benefit compared to standard dose of 30 or 50 IU/kg three times per week. Conclusion The results of the study demonstrate the feasibility of individualizing infusion interval, restricting FVIII dose, trough and peak concentration within an acceptable range.
Stroke in the young: relationship of active cocaine use with stroke mechanism and outcome

Background Cocaine and other vasoactive substances are known causes of cerebrovascular disease. Ictus during drug intake adversely affects outcome.
LVAD Surgical Implant Technique: Extraperitoneal Approach

As the number of LVAD implantations continues to rise and the technology advances, alternate approaches and new techniques have continued to develop. This chapter aims to not only summarize the steps common to the traditional LVAD implantation approach but also to introduce, explore, and summarize the increasing minimally invasive approaches, the variants in outflow graft (OG) anastomosis sites and their perceived benefits, and the varying approaches to “off-pump” LVAD implantation that circumvent the operative risks associated with the use of cardiopulmonary bypass (CPB).
Verification & validation on OCO-3: A case study of V&V for ISS missions

The Orbiting Carbon Observatory-3 (OCO-3) payload will complete final Assembly Integration and Test operations in early 2018. Concurrently, the payload will undergo a suite of Verification and Validation (V&V) activities in order to demonstrate that the payload has met the project requirements. These activities will also demonstrate launch readiness and ultimately mission readiness to quantify variations in the column averaged atmospheric carbon dioxide (CO2) dry air mole fraction, XCO2 from the International Space Station (ISS). Operating from the ISS has its own set of advantages and challenges. One of the aspects of operating on the ISS includes going through a distinctive verification and validation process unique to ISS payloads. This process includes the use of the National Aeronautics & Space Administration (NASA) Verification of Engineering Requirements — Interface for Tracking, Approval and Submission (VERITAS) system to facilitate multiple center interactions and review of interface requirements. In this paper we will discuss how the OCO-3 V&V Program architecture interfaced with the ISS payload interface V&V program to show that the mission requirements were met.
Structural Effects in Magnetoresistive Manganites and Mechanism of Metal-Insulator Transition

Colossal magnetoresistivity (CMR) is caused by a magnetic field-induced insulator-to-metal transition. It is arguably one of the most dramatic phenomena that occur in solids due to competing forces in a complex system. In the CMR oxides the electron-phonon coupling and spin correlations that favor charge localization are competing against the electron kinetic energy and lattice elasticity that prefer charge delocalization. The CMR phenomenon occurs at the crossover point of charge-localized (insulating) and charge-delocalized (metallic) states, where the system is particularly susceptible to external stimuli such as a magnetic field. The competitions among these forces are usually considered globally as volume averages. However, since the system is complex and the phenomenon is non-linear, local fluctuations dominate the behavior of the system near the critical point. Therefore the system would appear spatially inhomogeneous if the measurement is made with certain time and length scales. To characterize and understand such a system it is required to deploy local approaches in which the competing interactions are evaluated locally. Experimentally, the pulsed neutron pair-density function (PDF) analysis is one of the methods of local structural study. Using the PDF technique it is suggested that the phase transition occurs via local and percolative processes. Also through the analysis of the local structure it is shown that the ionic size effect on the CMR phenomenon is not caused by a change in the band width as is usually assumed, but is due to local structural changes that affect polaron stability. The critical ionic size determined by this approach is in excellent agreement with experimental observations. The PDF results also indicate that the local structure of layered manganites is close to that of perovskite, suggesting that they share common elements of the CMR mechanisms.
Numerical Study of High Field Transport in SiO2 with Traps: A Coupled Monte Carlo and Rate Equation Model

The physical problem addressed in this paper is that of hot electron transport in silicon dioxide with traps. A rate equation model solved self consistently [1,2] has previously been shown to agree well with experimental data for the flat band voltage shift in silicon dioxide. This dynamic trapping and detrapping model contains an empirical detrapping cross section. By using a Monte Carlo algorithm to calculate a microscopic local detrapping cross section, an improved version of the self consistent rate equation model is obtained.
Price-Cap Regulation of Firms that Supply Their Rivals

We study price-cap regulation in a market in which a vertically integrated upstream monopolist sells an essential input to a downstream competitor. In the absence of regulation, entry benefits both firms, but may be detrimental to downstream consumers because the upstream monopolist can set a high input price that will push downstream prices above the monopoly level. However, if a regulator caps the incumbent's upstream and downstream prices, consumers and firms benefit from entry. Using a dynamic extension of the model, we explore the concern that price caps may induce incumbents to forgo cost-reducing investments and dampen entrants' incentives to self-provision the input.
Buried Narratives: Exhuming the Mother's Story in Oliver Twist

Initially, Oliver Twist (1839) might seem representative of the archetypal male social plot, following an orphan and finding him a place by discovering the father and settling the boy within his in...
Iterative Phase Correction Technique for Design of Non-Conventional Reflectarray Antennas

This paper introduces an iterative technique for mitigating phase errors of reflectarray antenna elements illuminated at high oblique incidence angles. The reflectarray is designed for a compact unmanned aerial vehicle (UAV) at 5.8 GHz ISM band. The proposed iteration methodology follows the conjugate field matching technique to estimate the phase error in each element. These errors are corrected iteratively using an adaptive phase-response tracking loop, resulting in 0.8 and 2.6 dB improvements in gain and sidelobe level, respectively.
Alcohol and marijuana use among young injured drivers in Arizona, 2008-2014.

AbstractObjective: We examined alcohol and marijuana use among injured drivers aged 16–20 years evaluated at Arizona level 1 trauma centers during 2008–2014.Methods: Using data from the Arizona Sta...
Cataract-associated deamidations on the surface of γS-crystallin increase protein unfolding and flexibility at distant regions

Deamidation is a major age-related modification in the human lens that is highly prevalent in crystallins isolated from cataractous lenses. However, the mechanism by which deamidation causes proteins to become insoluble is not known, because of only subtle structural changes observed in vitro. We have identified Asn14 and Asn76 of {gamma}S-crystallin as highly deamidated in insoluble proteins. These sites are on the surface of the N-terminal domain and were mimicked by replacing the Asn with Asp residues. We used heteronuclear NMR spectroscopy to measure their amide hydrogen exchange and 15N relaxation dynamics to identify regions with significantly increased dynamics compared to wildtype-{gamma}S. Changes in dynamics were localized to the C-terminal domain, particularly to helix and surface loops distant from the mutation sites. Thus, a potential mechanism for {gamma}S deamidation-induced insolubilization in cataractous lenses is altered dynamics due to local regions of unfolding and increased flexibility.
Stereospecific preparation of (1E,3E,5E)-3.4-difluoro-1,6-diphenylhexatriene and (2E,4E,6E)-diethyl-4,5-difluoroocta-2,4,6-trienedioate

Abstract Palladium(0) catalyzed coupling of β-bromostyrene (E/Z = 89/11) with (E)-(1,2-difluoro-1,2-ethenediyl)bis[tributylstannane], 1, in DMF at room temperature stereospecifically gave only (1E,3E,5E)-3,4-difluoro-1,6-diphenylhexatriene. Similarly, palladium(0) catalyzed coupling of (E)-ethyl 3-bromoacrylate as the vinyl halide precursor stereospecifically gave (2E,4E,6E)-diethyl-4,5-difluoroocta-2,4,6-trienedioate. This work demonstrates that a non-fluorine-containing vinyl bromide will selectively undergo coupling with 1 and enable the stereospecific preparation of a mixed polyene system. The (E)-ethyl 3-bromoacrylate coupling with 1 illustrates that mixed functionalized hexatriene systems can be easily accessed via this methodology. The X-ray structure of (2E,4E,6E)-diethyl-4,5-difluoroocta-2,4,6-trienedioate confirmed its structure.
Einsatzmöglichkeiten osteochondraler Allografts

Transplantationen von frischen osteochondralen Allografts (OCA) konnen zur Primartherapie einer Vielzahl unterschiedlicher Gelenkverletzungen und Erkrankungen eingesetzt werden und stellen auch im Revisionsfall nach nicht erfolgreicher Knorpeltherapie eine alternative Behandlungsmethode dar. Grose und tiefe (osteo)chondrale Defekte konnen dabei mit nur einem Eingriff vollstandig rekonstruiert werden. Dem Patienten bietet sich ein Verfahren, dass zuverlassig Schmerzen reduziert, zu langanhaltender Funktionsverbesserung fuhrt und im besten Fall eine endoprothetische Versorgung verhindert oder zumindest verzogert.
Infaunal augurs of the Cambrian explosion: An Ediacaran trace fossil assemblage from Nevada, USA.

Morphologically complex trace fossils, recording the infaunal activities of bilaterian animals, are common in Phanerozoic successions but rare in the Ediacaran fossil record. Here, we describe a trace fossil assemblage from the lower Dunfee Member of the Deep Spring Formation at Mount Dunfee (Nevada, USA), over 500 m below the Ediacaran-Cambrian boundary. Although millimetric in scale and largely not fabric-disruptive, the Dunfee assemblage includes complex and sediment-penetrative trace fossil morphologies that are characteristic of Cambrian deposits. The Dunfee assemblage records one of the oldest documented instances of sediment-penetrative infaunalization, corroborating previous molecular, ichnologic, and paleoecological data suggesting that crown-group bilaterians and bilaterian-style ecologies were present in late Ediacaran shallow marine ecosystems. Moreover, Dunfee trace fossils co-occur with classic upper Ediacaran tubular body fossils in multiple horizons, indicating that Ediacaran infauna and epifauna coexisted and likely formed stable ecosystems.
Uncertainties in Climate and Weather Extremes Increase the Cost of Carbon

Climate change has myriad physical and economic impacts. Even those that can be easily quantified indicate the need for ambitious climate action. Other climate impacts have yet to be quantified. We argue here that uncertainties in climate and weather extremes only further increase the social cost of carbon emissions.
Memory Load Effect in the Real-Time Processing of Scalar Implicatures

This study examines effects of memory load on the processing of scalar implicature via a dual-task paradigm using reading span and self-paced reading. Results indicate that participants showed online sensitivity to underinformative sentences (e.g., Some birds have wings and beaks) at the end of the sentence. This online sensitivity disappeared when participants were under increased memory load. Moreover, participants in the memory-load condition did not show sensitivity to semantically false sentences (e.g., All books have pictures and drawings). These results pose important conceptual and methodological questions of (1) whether the processing cost associated with scalar implicatures can be attributed to general proposition evaluation rather than scalar implicature derivation per se (Bale et al. in Semant Linguist Theory 20:525-543, 2010), and (2) to what degree memory load affects implicature computation only. I conclude with a discussion of these two issues for future research.
Open-source 128-channel bioamplifier module for ambulatory monitoring of gastrointestinal electrical activity

We present an open-source, low-cost, portable, 128-channel bioamplifier module designed specifically for ambulatory, long-term (≥24 hr) monitoring of gastrointestinal (GI) electrical activity. The electronics hardware integrates stateof-the-art, commercial-off-the-shelf components on a custom PCB. Features include on-board data logging, wireless data streaming, subject motion monitoring, and stable operation up to the maximum 2 kHz/channel sampling rate tested. The new device operates for ≈ 30 hr continuously powered by a single 3.7 V, 2500 mAh LiPo battery. The 3D-printed ABS mechanical enclosure is robust and small (13.1 × 8.8 × 2.5 cm), so that the device can be carried in a standard Holter monitor pouch. Results from initial 128-channel, high spatial resolution body surface colon mapping experiments demonstrate the utility of this new device for GI applications. The new bioamplifier module could also be used for multichannel recording experiments in a variety of biomedical domains to study electrical activity patterns of the neuromuscular system (EMG), uterus (EHG), heart (ECG), and brain (EEG).
Abstract 14296: Differential Left and Right Ventricle Response to Cold Storage Followed by Reperfusion in Heart Transplantation

Introduction: In heart transplantation, the supply of donor hearts is contributed by the short tolerable preservation period with risk for primary graft dysfunction. Understanding the differential ...
Simulating COVID-19 containment measures using the South Korean patient data: poster abstract

As the COVID-19 outbreak evolves around the world, the World Health Organization (WHO) and its Member States have been heavily relying on staying at home and lock down measures to control the spread of the virus. In last months, various signs showed that the COVID-19 curve was flattening, but the premature lifting of some containment measures (e.g., school closures and telecommuting) are favouring a second wave of the disease. The accurate evaluation of possible countermeasures and their well-timed revocation are therefore crucial to avoid future waves or reduce their duration. In this paper, we analyze patient and route data collected by the Korea Centers for Disease Control & Prevention (KCDC). We extract information from real-world data sets and use them to parameterize simulations and evaluate different what-if scenarios.
Adopting Hands-Off Approaches to Activism: Examining PSTs’ Experiences Navigating Visibility and Vulnerability as Teacher Activists:

This case study examines six English Language Arts (ELA) preservice teachers (PSTs) and the ways they recognize injustice and inequity in education, plan for addressing such issues, and engage as t...
Incidence and Significance of Elevated Transaminases in Infants with Failure to Thrive

Introduction Despite guidelines discouraging investigations for infants with failure to thrive (FTT) before adequate nutrition is established, laboratory testing is pursued in 60-90% of cases. Mild transaminase elevations are noted in some cases, potentially prompting further testing. The incidence and significance of transaminase elevation in infants with nutritional FTT is unknown. Objective Determine the frequency of transaminase elevation in infants with FTT and characterize their diagnostic …
Adaptive Frequency Response Reserve based on Real-time System Inertia.

To ensure adequate and economic reserve for primary frequency response in the current and future power system, this paper proposes real-time frequency response reserve (FRR) requirement based on system inertia. This minimum FRR will help power system operators adjust the current frequency response requirement and accommodate more renewable generations while achieving a saving of both energy and facility costs. Most importantly, the ability to adaptively vary the FRR will provide the additional agility, resiliency, and reliability to the grid.
Grounding Predicates through Actions

Symbols representing abstract states such as "dish in dishwasher" or "cup on table" allow robots to reason over long horizons by hiding details unnecessary for high level planning. Current methods for learning to identify symbolic states in visual data require large amounts of labeled training data, but manually annotating such datasets is prohibitively expensive due to the combinatorial number of predicates in images. We propose a novel method for automatically labeling symbolic states in large-scale video activity datasets by exploiting known pre- and post-conditions of actions. This automatic labeling scheme only requires weak supervision in the form of an action label that describes which action is demonstrated in each video. We apply our framework to an existing large-scale human activity dataset. We train predicate classifiers to identify symbolic relationships between objects when prompted with object bounding boxes and achieve 0.93 test accuracy. We further demonstrate the ability of these predicate classifiers trained on human data to be applied to robot environments in a real-world task planning domain.
Red-Light-Induced N,N′-Dipropyl-1,13-dimethoxyquinacridinium-Catalyzed [3+2] Cycloaddition of Cyclopropylamines with Alkenes or Alkynes

A red-light-mediated [3+2] annulation of cyclopropylamines with akenes or alkynes in the presence of N,N′-dipropyl-1,13-dimethoxyquinacridinium is reported. An array of cyclopentane or cyclopentene derivatives with diverse functional groups have been obtained in moderate to excellent yields under mild conditions.
Competing Values and Evidence: How Do We Evaluate Mandated Reporting and CPS Response?

Child protection policy relative to mandated reporting is analyzed in this chapter, beginning with a review of general values and goals in child welfare as found in international, national, and regional policy and law. We then use the best available empirical evidence to address a set of long-standing but largely flawed assumptions pertaining to the issue of mandated reporting. We discuss current services available in child protection, with an emphasis on emerging practices for children served in their homes. Finally, we conclude with a number of suggestions for future research and policy developments in this area.
Law and the Open Internet

The Federal Communications Commission (FCC) is poised to issue a new set of internet access regulations and policies. These would prohibit broadband service providers, such as AT&T or Comcast, from “discriminating” against unaffiliated content providers. The FCC’s proceedings, and the network neutrality debate, concentrate on two economic questions (i) whether to broadband service providers can or will steer traffic to affiliated content limiting consumer access and (ii) how to preserve the Internet’s capacity for creativity and innovation. Despite economics’ prominence in the debate, economic theory cannot answer these questions. Theoretical models of vertical foreclosure are ambiguous and inconclusive and empirical data nonexistent. And, the debate misapplies normative, legal concepts of “discrimination” and “equal treatment” onto internet traffic management engineering. These concepts worked in a circuit switched telephone network in which “equality” can exist at switch points, but make little sense in the packet-switched internet in which “equality of outcomes” of internet experience is what matters.With its narrow focus, the debate has also missed that actual internet disputes, such as the BitTorrent-Comcast Order, involve many legal concerns, such as privacy, that have little to do with “discrimination” as such. Policymakers lack theoretical understanding and empirical knowledge concerning internet industrial organization. We, therefore, argue for a “bottom up” approach to regulation, analogous to fair use in copyright law, with case-specific adjudications creating a common law of acceptable network practice.
Biofilm structure and mass transfer in a gas phase trickle-bed biofilter

Mass transport phenomena occurring in the biofilms of gas phase trickle-bed biofilters are investigated in this study. The effect of biofilm structure on mass transfer mechanisms is examined using experimental observation from the operating of biofilters, microelectrode techniques and microscopic examination. Since the biofilms of biofilters used for waste gas treatment are not completely saturated with water, there is not a distinguishable liquid layer outside the biofilm. Results suggest that due to this characteristic, gas phase substrates (such as oxygen or volatile organic compounds) may not be limited by the aqueous phase because transport of the compound into the biofilm can occur directly through non-wetted areas. On the other hand, for substrates that are present only in the liquid phase, such as nitrate, the mass transfer limitation is more serious because of the limited liquid supply. Microscopic observations show that a layered structure with void spaces exists within the biofilm. Oxygen concentration distributions along the depth of the biofilms are examined using an oxygen microelectrode. Results indicate that there are some high dissolved oxygen zones inside the biofilm, which suggests the existence of passages for oxygen transfer into the deeper sections of the biofilm in a gas phase trickle-bed biofilter. Both the low gas-liquid mass transfer resistance and the resulting internal structure contribute to the high oxygen penetration within the biofilms in gas phase trickle-bed biofilters.
pfs: parallelized, flow-based network simulation

Simulation is a compelling option for evaluating Internet protocols, configurations and behaviors. While current simulation tools have been used effectively to consider questions in small-scale networks, they are incapable of evaluating large scale phenomena such as routing configurations, DDoS attacks and data center deployments. In this paper, we describe pfs, a parallelized version of the fs flow-level simulator [1] that offers the opportunity to conduct very large-scale simulations of networks. Our approach to parallelization is based on decomposing simulation configurations both spatially and temporally into independent chunks that can be run simultaneously on massively scalable, parallel processing infrastructures. We demonstrate the capabilities of pfs through a series of experiments that highlight both the speedup that can be achieved as well as the costs that are incurred in terms of the accuracy of the simulation results.
Killing Them Softly: Forcible Transfers of Indigenous Children

The forcible transfer of indigenous children in North America and Australia are part of a global phenomenon that consisted of the kidnapping, trafficking, removal, and identity changes of children of particular groups. Article II(e) of the United Nation Convention on the Prevention and Punishment of Genocide prohibits the forcible transfer of children of a group to another group (FTC). The FTC echoes domestic and international legal norms and policies for the protection of children since early twentieth century. Its particular applicability to specific victims within a protected group – children –conveys a unique ethical position compared to the other acts enumerated acts in Article II, and the UNGC as a whole. This uniqueness may justify the much needed conceptual leap from the legalistic western-biased notion of genocide towards a more inclusive recognition of the political, social, and economical aspects of genocide.
Instrument Tracking and Visualization for Ultrasound Catheter Guided Procedures

We present an instrument tracking and visualization system for intra-cardiac ultrasound catheter guided procedures, enabled through the robotic control of ultrasound catheters. Our system allows for rapid acquisition of 2D ultrasound images and accurate reconstruction and visualization of a 3D volume. The reconstructed volume addresses the limited field of view, an inherent problem of ultrasound imaging, and serves as a navigation map for procedure guidance. Our robotic system can track a moving instrument by continuously adjusting the imaging plane and visualizing the instrument tip. The overall instrument tracking accuracy is 2.2mm RMS in position and 0.8° in angle.
Comparing tests of the theory of exhaustible resources

Abstract The empirical relevance of Hotelling’s exhaustible resource theory has been tested with primarily negative results. Tests have been performed on various resources, at different levels of aggregation, with varying market structures, and over different time periods. Consequently, it is difficult to draw any general conclusions concerning the theory’s applicability in explaining producer behavior, given the assumptions and restrictions implicit in the data and tests. This paper compares test results when the implicit restrictions associated with the data are removed. Employing a single data set we compare the results for four published tests. Even with this uniform data set, two approaches reject the theory while two do not.
The Incidence of Central Retinal Artery Occlusion in Olmsted County, Minnesota

Purpose To determine the incidence of central retinal artery occlusion in Olmsted County, Minnesota. Design Retrospective chart review. Methods Medical records of all patients living in Olmsted County, Minnesota between 1976 and 2005 diagnosed with central retinal artery occlusion were identified using the Rochester Epidemiology Project medical records linkage system. Results Forty-three cases were identified for an unadjusted annual incidence in the female population of 1.02 per 100 000 and 1.67 per 100 000 in the male population, with a combined incidence of 1.33. Incidence rates were also age- and/or sex-adjusted to the 2000 census figures for the US white population using direct standardization. Age-adjusted annual incidence per 100 000 for the female population was 1.15 (95% confidence interval [CI], 0.60–1.71), for the male population was 2.78 (95% CI, 1.69–3.86), and combined was 1.87 (95% CI, 1.31–2.43). When adjusted for age and sex, the incidence was 1.90 per 100 000 (95% CI, 1.33–2.47). Conclusion Central retinal artery occlusion is a rare event. The incidence is 1.3 per 100 000 in Olmsted County, Minnesota, or 1.90 per 100 000 when age- and sex-adjusted for the United States white population.
EXPERIMENTAL RESULTS FOR THE SMALL-SIGNAL STUDY OF THE PWM BOOST DC–DC CONVERTER WITH AN INTEGRAL-LEAD CONTROLLER

An experimental verification of previously derived small-signal low-frequency open- and closed-loop characteristics and step responses of a voltage-mode-controlled pulse-width-modulated (PWM) boost DC–DC converter is presented. The Bode plots of the voltage transfer function of the control circuit, the converter and the PWM modulator, the open-loop control-to-output and input-to-output transfer functions, the loop gain, and the closed-loop control-to-output and input-to-output transfer functions are measured. The step responses to the changes in the input voltage, the duty cycle, and the reference voltage are measured. The theoretical results were in good agreement with the measured results. The small-signal model of the converter is experimentally verified.
Extensive nasal septum resection in horses using a 3-wire method.

Objective— To describe a surgical technique for, and report outcome after, extensive nasal septum resection in horses with congenital or acquired septal diseases. Study Design— Retrospective study. Animals— Horses (5) with nasal septal deformity. Methods— Under general anesthesia, obstetrical wires were preplaced around the ventral, caudal, and dorsal aspects of the nasal septum by combinations of manual guidance (ventral and caudal wires) and use of a trephine hole on the dorsal mid-line (dorsal and caudal wires). The rostral part of the septum was incised with a scalpel and the ventral, dorsal, and caudal septal incisions were made with the preplaced wires. After septum removal, the nasal cavity packed with a tampon and a temporary tracheotomy was performed. Results— The diseased nasal septum was completely removed in all horses. It was possible to direct the caudal cut at a sufficient angle so that the remaining stump was in a wide part of the nasal passage, where it would have minimal effect on airflow. Four horses healed, and returned to intended use but continued to make a slight respiratory noise during exercise. At 13 months after surgery, 1 horse with a concurrent wry nose was retired from race training after 2 additional surgeries failed to relieve exercise intolerance at high speed. Conclusions— The 3 wire-cut method of nasal septum resection was technically easy to perform and safe, allowed return to function in most horses, and produced an excellent cosmetic appearance. Clinical Relevance— This technique for nasal septum resection allows removal of a large portion of the nasal septum and provides a safe alternative to conventional techniques of nasal septum resection in the horse.
Nuclear Magnetic Resonance and Gas Chromatography/Mass Spectroscopy Analysis of the Nonvolatile Components Produced during Heating of Oleic Acid Esterified Propoxylated Glycerol, a Fat Substitute Model Compound, and Trioleylglycerol

Oleic acid esterified propoxylated glycerol (EPG-08 oleate) and trioleylglycerol were heated separately (192 ± 8 °C for 12 h/day) until the polymer content was ≥20% and examined. Supercritical fluid fractionation (SFF) produced a monomer fraction of 98.3% purity and a dimer fraction of 90.8% purity for heated EPG-08 oleate and comparable fractions for triolein. Carbon-13 NMR analysis of the fractionated dimer (SFF-D) oil samples indicated peaks at approximately 107−108, 67−68, and 23.8 ppm that were present in only the SFF-D samples. The presence of these peaks in both samples indicated that the presence of the oxypropylene backbone was not necessary for the formation of the bonds corresponding to these peaks. The oxypropylene backbone profile was the same for the day 0 and the SFF-D sample. Gas chromatography/mass spectrometry of dimeric fatty acid methyl esters indicated that the fatty acid portion of the molecule was involved in dimer formation for both oil samples. Keywords: Oleic acid esterified prop...
The nature and origin of the multiple polarographic wave observed during the one-electron reduction of aquated bis(ethylenediamine)cobalt(III) ions

Abstract The polarographic behavior of a series of aquated bis(ethylenediamine)cobalt(III) ions has been studied in buffered and unbuffered aqueous solution. In unbuffered solution, multiple waves, the relative heights of which are dependent upon pH, were obtained for the one-electron reduction to the cobalt(II) state. The first (most positive) wave is due to the direct reduction of the aquobis(ethylenediamine)cobalt(III) ion in solution, while later (more negative) waves are due to ligand exchange and the corresponding hydroxo compound formed by deprotonation of the parent aquo species. In basic solution, the dihydroxobis(ethylenediamine)cobalt(III) ion gives a single wave at the more negative potential because this ion is more stable than tris(ethylenediamine) cobalt(III) ion. In buffered solution, the multiplicity due to the acid and base forms of the aquated bis(ethylenediamine)cobalt(III) ions is eliminated.