cssi/SciSciGPT-SciSciNet huggingface dataset:
Impact of peri-transplant vancomycin and fluoroquinolone administration on rates of bacteremia in allogeneic hematopoietic stem cell transplant (HSCT) recipients: a 12-year single institution study.

Summary Background We analyzed the effect of peri-transplant prophylaxis on the epidemiology of bacteremia in a 12-year contemporary cohort of allogeneic HSCT recipients at our center. Methods This was an observational study of 1052 consecutive adult HSCT from 2000 to 2011. Formal prophylaxis with vancomycin only, fluoroquinolone (FQ) only, or vancomycin + FQ was implemented in 2006. The cumulative incidence of day 100 bacteremia was compared between the Early Period (2000–2005) and the Recent Period (2006–2011). Predictors for pre-engraftment bacteremia were analyzed with Cox-proportional hazard models in a subcohort of 821 HSCT who received myeloablative or reduced intensity conditioning (MA/RIC). Results The incidence of bacteremia decreased in the Recent Period (32% vs 27%; P = 0.002), whereas the rates of resistance in gram-negative rods (GNR) and vancomycin-resistant enterococci (VRE) were similar between the two Periods ( P values are not statistically significant.) In multivariate analyses, prophylaxis with vancomycin only or vancomycin + FQ was protective (HR = 0.5; CI = 0.30–0.72) and (HR = 0.3; CI = 0.12–0.52, P Conclusions Vancomycin-based prophylaxis peri-transplant in MA/RIC HSCT was associated with elimination of VSB and may be considered at centers with high incidence of this infection.
Using uml to visualize role-based access control constraints

Organizations use Role-Based Access Control (RBAC) to protect information resources from unauthorized access. We propose an approach, based on the Unified Modeling Language (UML), that shows how RBAC policies can be systematically incorporated into an application design. We consider an RBAC model to be a pattern which we express using UML diagram templates; RBAC policies for an application conforming to this model can be generated by instantiating these templates with values obtained from the application. The constraints of the RBAC model are expressed using the Object Constraint Language (OCL). OCL constraints, based on first-order logic, are difficult to understand. To alleviate this problem, we show how violation of such constraints can be visually represented using object diagram templates. With adequate tool support, developers can use these to demonstrate constraint violations in their applications. Our approach is illustrated using a small banking application.
Analysis of Hydrodynamic Stability of Solar Tachocline Latitudinal Differential Rotation using a Shallow-Water Model

We examine the global, hydrodynamic stability of solar latitudinal differential rotation in a "shallow-water" model of the tachocline. Charbonneau, Dikpati, & Gilman have recently shown that two-dimensional disturbances are stable in the tachocline (which contains a pole-to-equator differential rotation s < 18%). In our model, the upper boundary of the thin shell is allowed to deform in latitude, longitude, and time, thus including simplified three-dimensional effects. We examine the stability of differential rotation as a function of the effective gravity of the stratification in the tachocline. High effective gravity corresponds to the radiative part of the tachocline; for this case, the instability is similar to the strictly two-dimensional case (appearing only for s ≥ 18%), driven primarily by the kinetic energy of differential rotation extracted through the work of the Reynolds stress. For low effective gravity, which corresponds to the overshoot part of the tachocline, a second mode of instability occurs, fed again by the kinetic energy of differential rotation, which is primarily extracted by additional stresses and correlations of perturbations arising in the deformed shell. In this case, instability occurs for differential rotation as low as about 11% between equator and pole. If this mode occurs in the Sun, it should destabilize the latitudinal differential rotation in the overshoot part of the tachocline, even without a toroidal field. For the full range of effective gravity, the vorticity associated with the perturbations, coupled with radial motion due to horizontal divergence/convergence of the fluid, gives rise to a longitude-averaged, net kinetic helicity pattern, and hence a source of α-effect in the tachocline. Thus there could be a dynamo in the tachocline, driven by this α-effect and the latitudinal and radial gradients of rotation.
Internationalization and Changes in Tax Policy in OECD Countries: The Importance of Domestic Veto Players

This article examines the role that economic and political factors played in tax reform in Organization for Economic Cooperation and Development (OECD) countries from 1986 to 1990. Some writers argue that economic integration forced states to reform their tax systems. The authors' findings indicate that economic openness had an indirect effect on the level of change in marginal tax rates. The institutional structure of a country was most important—countries that had only one veto player or only one institution or party whose approval was necessary for a bill to become law enacted more sweeping reform than states that had more than one veto player. These results suggest that even when international or domestic economic factors might dictate a change in policy, reform will not be as sweeping in countries in which agreement among several institutions and/or parties is necessary.
Soil evaporation response to Lehmann lovegrass (Eragrostis lehmanniana) invasion in a semiarid watershed

Across the western United States, warm-season grasslands are being invaded by the exotic perennial grass, Eragrostis lehmanniana (Lehmann lovegrass). The objective of this study was to quantify the change in surface water balance, particularly the evaporation from bare soil, associated with E. lehmanniana invasion. Following a protracted drought, the Kendall grassland in the USDA-ARS Walnut Gulch Experimental Watershed in southeast Arizona transitioned from a diverse, native bunchgrass community to one dominated by E. lehmanniana. A network of 20 microlysimeters was deployed to measure daily soil evaporation (ED) in 2005 and again in 2007 (pre- and post-invasion years, respectively). This was supported with continuous measurements of evapotranspiration (ET), precipitation (P), runoff (R), surface soil moisture (u), and solar irradiance (L) at Kendall from 2002 to the present. An empirical equation was developed to derive ED based on u measured midday at 5 cm depth and average daily L. This was applied to years 2002–2007 during the vegetation growing season (June through October). Results confirmed that total ET over the growing season (ETS) was a function of � ).
Volcanoes as possible indicators of tectonic stress orientation — principle and proposal

Abstract A method is proposed for determining the orientation of average tectonic stress, using surface features indicating radial dike patterns of volcanoes. The approximate pattern of radial dikes is revealed by the distribution of sites of flank eruptions on the slope of polygenetic volcanoes. This conclusion is deduced from the understanding that flank eruptions are caused by the magma that laterally offshoots from the main polygenetic pipe conduit and that conduits of flank volcanoes are most probably fissure-shaped because most of them are monogenetic volcanoes. Radial dikes are more likely to develop in a direction normal to the minimum horizontal compression of the regional stress. Thus, the distribution of flank craters will be elongate in the direction of the maximum horizontal compression of the regional stress. The regional stress can sometimes be ascribed solely to the effect of the gravity rather than tectonic stress. When a number of independent polygenetic volcanoes dotted with more than several flank volcanoes, are distributed in a belt or over a broad area, it is possible to distinguish the tectonic stress from the direct gravitational effect by the regional uniformity in orientation of the zones of flank volcanoes. When the maximum compression of tectonic stress is horizontal, the trends of the zones of flank eruptions on polygenetic volcanoes are more or less linear and parallel, and at a high angle to the trend of the main volcanic belt.
Wideband low frequency antennas for radio astronomy arrays

Antennas in the frequency range 10 to 300 MHz are being designed with all-sky coverage, a low response at the horizon to minimize interference from terrestrial sources, negligible ground loss and a good low noise match to the low noise amplifier (LNA). Other features include low cost, dual polarization and good performance over more than an octave bandwidth. Extending the antenna performance over a wider frequency range and accurate calibration are remaining challenges. Modeling of the antenna and its associated low noise amplifier shows promise as a method of improving calibration accuracy.
Energy-efficient airtime allocation in multi-rate multi-power-level wireless LANs

This paper considers the energy-conservation problem in multi-rate multi-power-level wireless local area networks (WLANs). This problem is addressed from a unique angle --- the system-level fairness which is significantly different from most of current research that focuses on improving the performance of each individual wireless station. To emphasize fair energy-consumption among contending stations, we introduce a new fairness notion, called energy-conservation fairness, in contrast to the conventional throughput fairness and airtime fairness. Another contribution of the paper is an energy-efficient airtime allocation scheme, which allocates airtime shares to contending stations in such a way that the combined airtime and energy-conservation fairness is achieved. Our simulation results show that, when the energy-conservation fairness is considered, both aggregate system throughput and overall system energy-efficiency can be improved significantly with all contending stations consuming a similar amount of energy.
6-18F-DOPA PET study in patients with schizophrenia

Presynaptic dopamine metabolism was studied in a group of patients with schizophrenia and in an age- and gender-matched normal control group using 6-[(18)F]fluoro-L-DOPA ((18)F-DOPA) and positron emission tomography (PET). Nineteen patients, nine drug-free, 10 on neuroleptics, and 13 normal control subjects underwent PET scans using (18)F-DOPA. The neuroleptic-treated patients were taking typical neuroleptics (N=4) or the atypical neuroleptic, clozapine (N=6). The ratio of specific/non-specific activity was calculated for eight cortical and subcortical regions of interest. Medication-free patients had a significant reduction in (18)F-DOPA uptake in the ventral striatum (P=0.04) and significantly increased uptake in the posterior cingulate (P=0.02) compared with normal control subjects. The 18F-DOPA PET technique proved to be useful and sensitive in detecting changes in dopamine metabolism in patients with schizophrenia in vivo. The results of this study provide evidence of an aberrant dopamine system in schizophrenia.
Potential consequences of selection to change gestation length on performance of Holstein cows

Abstract Genetic evaluations for gestation length (GL) for Holstein service sires were studied to determine their effectiveness in predicting GL in an independent data set. Consequences of selection on GL were also assessed by examining correlated changes in milk and fitness traits. Holstein bulls with ≥300 calvings between 1998 and 2005 were stratified into the following 7 groups using predicted transmitting ability (PTA) for service sire GL:
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

Whereas several apoptosis-related proteins have been linked to the antiapoptotic effects of Akt serine–threonine kinase, the search continues to explain the Akt signaling role in promoting cell survival via antiapoptotic effects. Here, we demonstrate that Akt phosphorylates the androgen receptor (AR) at Ser-210 and Ser-790. A mutation at AR Ser-210 results in the reversal of Akt-mediated suppression of AR transactivation. Activation of the phosphatidylinositol-3-OH kinase/Akt pathway results in the suppression of AR target genes, such as p21, and the decrease of androgen/AR-mediated apoptosis, which may involve the inhibition of interaction between AR and AR coregulators. Together, these findings provide a molecular basis for cross-talk between two signaling pathways at the level of Akt and AR–AR coregulators that may help us to better understand the roles of Akt in the androgen/AR-mediated apoptosis.
Spatial Predictions of Cover Attributes of Rangeland Ecosystems Using Regression Kriging and Remote Sensing

Abstract Sound rangeland management requires accurate information on rangeland condition over large landscapes. A commonly applied approach to making spatial predictions of attributes related to rangeland condition (e.g., shrub or bare ground cover) from remote sensing is via regression between field and remotely sensed data. This has worked well in some situations but has limited utility when correlations between field and image data are low and it does not take advantage of all information contained in the field data. I compared spatial predictions from generalized least-squares (GLS) regression to a geostatistical interpolator, regression kriging (RK), for three rangeland attributes (percent cover of shrubs, bare ground, and cheatgrass [ Bromus tectorum L.]) in a southern Idaho study area. The RK technique combines GLS regression with spatial interpolation of the residuals to improve predictions of rangeland condition attributes over large landscapes. I employed a remote-sensing technique, object-based image analysis (OBIA), to segment Landsat 5 Thematic Mapper images into polygons (i.e., objects) because previous research has shown that OBIA yields higher image-to-field data correlations and can be used to select appropriate scales for analysis. Spatial dependence, the decrease in autocorrelation with increasing distance, was strongest for percent shrub cover (samples autocorrelated up to a distance [i.e., range] of 19 098 m) but present in all three variables (range of 12 646 m and 768 m for bare ground and cheatgrass cover, respectively). As a result, RK produced more accurate results than GLS regression alone for all three attributes when predicted versus observed values of each attribute were measured by leave-one-out cross validation. The results of RK could be used in assessments of rangeland conditions over large landscapes. The ability to create maps quantifying how prediction confidence changes with distance from field samples is a significant benefit of regression kriging and makes this approach suitable for landscape-level management planning.
Penetration of Rigid Projectiles Through Quasi-Brittle Materials

The objective of this study is to formulate a simple, rational model for estimates of the penetration depth of rigid long rods through materials susceptible to microcracking. The proposed is based on the target resistance estimated using the particle dynamic simulations. All material parameters of the model can be identified and measured in laboratory. The accuracy of this simple model is found to be satisfactory.
Effects of climate and landcover change on stream discharge in the Ozark Highlands, USA ∗

Stream discharge of a watershed is affected and altered by climate and landcover changes. These effects vary depending on the magnitude and interaction of the changes, and need to be understood so that local water resource availability can be evaluated and socioeconomic development within a watershed be pursued and managed in a way sustainable with the local water resources. In this study, the landcover and climate change effects on stream discharge from the Jacks Fork River basin in the Ozark Highlands of the south-central United States were examined in three phases: site observation and data collection, model calibration and simulation, and model experiment and analysis. Major results of the study show that climate fluctuations between wet and dry extremes resulted in the same change of the basin discharge regardless of the landcover condition in the basin. On the other hand, under a specified climate condition landcover change from a grassland basin to a fully forested basin only resulted in about one half of the discharge change caused by the climate variation. Furthermore, when landcover change occurred simultaneously with climate variation, the basin discharge change amplified significantly and became larger than the combined discharge changes caused by the climate and landcover change alone, a result indicating a synergistic effect of landcover and climate change on basin discharge variability.
Direct digital capture of pulse oximetry waveforms

Pulse oximetry sensor photodiodes typically generate a current proportional to the intensity of the pulse oximetry waveforms. This method of waveform capture is prone to electrical noise and requires analog-to-digital conversion downstream for further digital signal processing. This investigation evaluated the use of a light-to-frequency photodiode as an alternative sensor for capturing pulse oximetry waveforms. Red and infrared pulse oximetry waveforms were captured with a Texas Instruments TSL220 light-to-frequency converter. The fidelity of the captured waveforms was excellent. The compact TSL220 combination of photodiode, amplifier, and current-to-frequency converter can potentially replace the light-to-current photodiode, current-to-voltage converter, and analog-to-digital converter now used in typical pulse oximetry applications. >
Exploiting large-scale drug-protein interaction information for computational drug repurposing

Despite increased investment in pharmaceutical research and development, fewer and fewer new drugs are entering the marketplace. This has prompted studies in repurposing existing drugs for use against diseases with unmet medical needs. A popular approach is to develop a classification model based on drugs with and without a desired therapeutic effect. For this approach to be statistically sound, it requires a large number of drugs in both classes. However, given few or no approved drugs for the diseases of highest medical urgency and interest, different strategies need to be investigated. We developed a computational method termed “drug-protein interaction-based repurposing” (DPIR) that is potentially applicable to diseases with very few approved drugs. The method, based on genome-wide drug-protein interaction information and Bayesian statistics, first identifies drug-protein interactions associated with a desired therapeutic effect. Then, it uses key drug-protein interactions to score other drugs for their potential to have the same therapeutic effect. Detailed cross-validation studies using United States Food and Drug Administration-approved drugs for hypertension, human immunodeficiency virus, and malaria indicated that DPIR provides robust predictions. It achieves high levels of enrichment of drugs approved for a disease even with models developed based on a single drug known to treat the disease. Analysis of our model predictions also indicated that the method is potentially useful for understanding molecular mechanisms of drug action and for identifying protein targets that may potentiate the desired therapeutic effects of other drugs (combination therapies).
Clinical nutrition education--relevance and role models

Although Hippocrates recognized the importance of a good diet for the prevention of disease, clinical nutrition has emerged only recently as an important discipline in modern medicine. A uniform curriculum for teaching nutrition to medical students can be adapted for use with postgraduate residents and fellows in the setting of referrals of patients with many common diseases. The prospect that the medical profession will accept clinical nutrition as an essential discipline may be enhanced by the realization that cost-effective medical practice is optimized by wider application of nutrition principles to health maintenance and patient care.
An Implementation of Wireless Sensor Network in Monitoring of Parkinson's Patients Using Received Signal Strength Indicator

Remote monitoring of patients with movement disorders is currently being researched extensively with the help of Wireless Body Area Sensor Network (WBASN). e-Healthcare is one such popular WBASN application. We focus our research addressing an important issue of wireless monitoring of patients suffering from Parkinson's Disease (PD) for fall detection in order to avoid potential injuries. We also propose a non-invasive, wireless technique that could detect multiple occurrences of Freezing of Gait (FoG) over single or multiple days of observation. For wireless monitoring of patients, we would embed wireless sensors in patient's vicinity, such as his room and determine the values of Received Signal Strength Indicator (RSSI) from these sensors. RSSI can thus be used as one of the measures to detect falls of PD patients. Our initial results of embedding force sensors in person's shoe, suggest that it can be used to detect and record the number of occurrences of FoG, which is hard to reproduce at doctor's clinic, due to its relation with patient's consciousness at the hospital. We also propose to derive different mobility patterns for a PD patient based on the RSSI values during a day's activity and then train the system for intelligent analysis in future.
A new method for evaluating the normalized energy consumption in office buildings

Information derived from utility bills for commercial buildings can be directly used to define indices such as energy budget (kWh/m2/yr), energy cost ($/m2/yr) or load factor. An analysis of these data reveals patterns of energy use in buildings and serves to disaggregate the total energy use among major end-uses. For example, weathernormalization permits comparison of the energy consumption of a building in two different years by eliminating the effect of different climatic conditions. In this paper, a new method is presented for weather-normalization and is used to evaluate the normalized energy consumption in several office buildings in Montreal. Finally, the results derived from our new method are compared with those obtained from the well-known PRISM method, using utility bills from 24 gas-heated buildings and 14 electrically-cooled buildings.
A preliminary answer to the question of whether cribbing causes salivary secretion

Abstract It has been hypothesized that cribbing, the equine oral stereotypy, may increase salivary production and, therefore, reduce gastric acidity in a species prone to gastric ulcers. To test the hypothesis that cribbing stimulates salivary secretion, parotid salivary duct fistulas were surgically created in 2 horses. In the first experiment, saliva was collected while the number of crib bites was counted. There was no significant relation ( r 2 = 0.022) between the numbers of crib bites and the volume of saliva produced. The second experiment involved measuring salivary output when one horse was cribbing and when he was eating, but could not crib. Before feeding, the horse produced 1 (0-2) mL of saliva while displaying 20 crib bites. The horse produced 31 (2-212) mL of saliva while eating 200 g of grain. After eating, the horse produced 2 (1-10) mL of saliva while displaying 20 crib bites. There was a significant difference in saliva production associated with eating (Kruskal–Wallis statistic=12.42, P
Multiscale TILT Feature Detection with Application to Geometric Image Segmentation

Motivated by the theory of low-rank matrix representation, a new type of invariant image feature, called transform-invariant low-rank texture (TILT), has been recently proposed. However, the application of TILT features in computer vision has been severely limited by two major problems. First, TILT feature representation is based on the assumption that the given image contains only one dominant low-rank region, which typically does not hold in natural images. Second, when multiple low-rank regions are present, the existing TILT detection methods either randomly sample the image or apply to fixed grid coordinates, both of which cannot guarantee good recovery of salient low-rank image features. In this paper, we propose a novel algorithm to address these two important issues. First, utilizing super pixels and the concept of canonical rank derived from TILT, we introduce a method to segment natural images into a geometric layer and a non-geometric layer. Second, we apply a Markov random field model to a multiscale low-rank representation of the image geometric layer, and obtain an effective algorithm to detect TILT features. Finally, we present an application of the multiscale TILT detection algorithm to the classical problem of building facade segmentation. Extensive experiments are conducted on the Pankrac building database to demonstrate the efficacy of the algorithms.
Comparative analysis of sequences of mitochondrial genomes of wild abortive male sterile (WA-CMS) and male fertile lines of rice, development of functional markers for WA-CMS trait and their use in assessment of genetic purity of seeds of WA-CMS lines

WA-CMS system based rice hybrids are widely adopted in many rice growing countries, including India. Even though it is well known that the trait is controlled by mitochondria, the genes underpinning the trait remain enigmatic. In the present study, a complete genome-wide comparative sequence analysis was performed using draft mitochondrial genomes of WA-CMS and male fertile lines in a step-wise manner, progressively covering 5–10 kb every time through BLASTN tool. The sequence polymorphisms identified in different mitochondrial regions were targeted to develop two different sets of dominant PCR-based markers, one consisting of six markers targeting WA-CMS mitochondria, the other set consisting of five markers targeting male fertile mitochondria in addition to development of a set of eight co-dominant PCR-based markers targeting both the genomes. When a set of candidate genes/ORFs reported earlier to be associated with WA-CMS trait in rice were analyzed through RT-PCR of RNA isolated from immature rice florets, it was observed that the chimeric ORF, WA352 is expressed only in WA-CMS line and hybrid (i.e. genotypes containing sterile mitochondria), indicating it’s candidacy for the WA-CMS trait. Targeting the functional nucleotide polymorphism between WA-CMS and maintainer mitochondria with respect to WA352, two dominant markers, one targeting sterile and another targeting fertile mitochondria were developed. In addition, a robust, co-dominant functional marker targeting the candidate gene was also developed and validated for its utility in identification of genetic impurities in seed lots of WA-CMS lines.
ROLE OF CYTOCHROMES AND OTHER METALLOPROTEINS IN THE PHOTOSYNTHETIC ELECTRON TRANSPORT

Publisher Summary This chapter discusses role of cytochromes and other metalloproteins in the photosynthetic electron transport. Current understanding of the mechanism of photosynthesis leans heavily on a concept of a photosynthetic, i.e., light-induced, electron transport. Photosynthetic phosphorylation (photophosphorylation) in chloroplasts is subdivided into two types, cyclic and noncyclic. The cyclic and noncyclic photophosphorylation jointly account for the basic feature of photosynthesis, i.e., conversion of radiant energy into chemical energy. The wavelength dependence of the phosphorylation associated with electron flow from an artificial electron donor (DPIPH2) to NADP resembles the cyclic system. It is well established that treating chloroplasts with ferricyanide in the dark chemically oxidizes several chloroplast constituents including cytochromes. The spectrum of the photoinduced decrease in absorbance had a maximum at 550 nm that was suggestive of an α-peak of a new cytochrome of a c-type.
Quantitatively Demonstrating the Complex Nature of Intimate Partner Violence

Background, Aims & Objectives. While some critics argue that complexity science concepts in qualitative medical research are used mainly as a novel metaphor, quantitative research does suggest that intimate partner violence (IPV) is non-linear in its dynamics, its decision-making, and effects of community interventions. The purpose of this study was to quantitatively demonstrate that complex adaptive systems dynamics are present in violent relationships. Methodology. Two hundred women in violent relationships were recruited from primary care settings and asked to report daily on the presence of violence and the household environment for 12 weeks using a telephone-based, interactive verbal response method. Attitudinal, behavioural, and clinical outcomes were assessed at the end-of-study interview. Analysis employed three non-linearity measurements to classify dynamic pattern when possible, vector auto-regression using multiple concurrent time series to develop models explaining other variables’ time series, orbital decomposition (based on symbolic dynamics) using categorical time series to identify recurrent patterns of strings, and staged multiple regression. Results. The 200 participants provided 9618 daily assessments; women reported abuse on 39 % of days, while perpetrating violence themselves on 23 % of days. First, based on non-linearity assessments of daily violence, IPV generally displayed non-linearity with only a few relationships exhibiting periodic dynamics. Second, using vector auto-regression, relationship violence involved multiple, interdependent factors, circular causality, and feed-forward dynamics as expected in complex systems. Third, using orbital decomposition, we observed recurrent multi-day, alcohol–violence patterns suggesting attractors within dynamic patterns. Fourth, after controlling for demographics and violence frequency and severity, measures of violence non-linearity predicted three of five attitudinal/behavioural outcomes and two of four clinical outcomes. Conclusions. IPV is a complex phenomenon, quantitatively demonstrating many of the features expected in complex systems. As this study shows, IPV is non-linear, non-causal and attractor-laden, and violence dynamics contributes to relevant outcomes. Complexity science is not just a metaphor; it is a paradigm with explanatory power.
In vitro comparison of the thrombin time and activated partial thromboplastin time in the laboratory control of heparin therapy.

An in vitro model was employed to compare the activated partial thromboplastin time and the thrombin time in monitoring heparin anticoagulation. The data demonstrate that the thrombin time may provide misleading information if used to monitor heparin therapy among patients being weaned from heparin to coumadin, and among patients with von Willebrand’s disease. This misinformation could result in serious hemorrhagic complications.
Determination of kelthane and pyrethroid pesticides in vegetables by capillary gas chromatography

Objective:To determine the pesticide multiresi-dues in vegetables effectively,a rapid and economical capi-llary gas chromatography method has been established for the determination of kelthane and pyrethriodes in vegetables.Methods:The pesticide residues in the samples were extracted with acetonitrile and then extracts concentrated with steam of nitrogen and cleaned up by silicon dioxide solid phase extraction column.Extracts were separated by HP-5(30 m×0.25 mm×0.25 μm) capillary column and detected by electroncapture detector.Results:The recoveries obtained from vege-tables were in the range of 67.8%~118.3%,with relative standard deviation of 3.2%~13.5%.Conclusion:This method is rapid,accurate and of less cost.It is suitable for the analysis of pesticide multi-residues in vegetables.
Normal reference values of peripheral blood CD3+,CD4+ and CD8+ T lymphocytes in healthy Miao ethnics in Hunan Province

Objective To understand and establish the normal reference values of peripheral blood CD3+,CD4+ and CD8+ T lymphocytes in healthy Miao ethnics in Hunan Province.Methods Three hundred and sixty healthy Miao ethnics were divided into 5 age groups(10~19,20~29,30~39,40~49,50~59),their peripheral blood CD3+,CD4+ and CD8+ T lymphocytes were detected with FACSCalibur flowcytometry.Results The mean absolute values of peripheral blood CD3+,CD4+,CD8+T lymphocytes and CD4+/CD8+ in healthy Miao ethnics in 10～59 age groups were(1 426.71±462.92)cells/μL,(787.54±258.36)cells/μL,(589.86±242.91)cells/μL and 1.46±0.50 respectively,the mean absolute values of peripheral blood CD3+ and CD8+T lymphocytes in 10~19 age group were significantly higher than those in 30~59 age group(F=10.80,8.51,respectively,all P0.05),CD4+T lymphocytes value was obviously higher than that in 50～59 age group(F=7.03,P0.05);There was on significant difference in above values between different genders(t=0.98,0.80,0.88,0.16 respectively,all P0.05).Conclusion The establishment of normal reference values of peripheral blood CD3+,CD4+ and CD8+T lymphocytes for healthy Miao ethnics will help to clinical diagnosis.
Suicide: Across the Life Span

Suicide remains a major public health issue. There have been more than 40,000 deaths by suicide in 2014. Understanding both the neuroscience and psychological development is key for nursing care so adequate interventions and treatment strategies are developed when working with people thinking about suicide. It is critical to assess and recognize risk and protective factors to ensure patient safety. The older adult, children, and adolescent populations remain vulnerable to suicide. A discussion regarding the psychiatric, psychosocial, and treatment considerations for these populations is included. An overview of communication, suicide assessment, and safety planning is discussed.
Corydon revisited: an interpretation of the political eclogues of Calpurnius Siculus

The first thing that the student of Vergilian pastoral may notice in turning to the pastoral Eclogues of Calpurnius Siculus is the obvious symmetrical arrangement of the poems in the later book. While the multitudinous inter-lacings of theme and subject in Vergil's ten poems continue to tease and baffle investigations of the larger organizational pattern, the principles of Calpurnius' design are simple and clear. Instead of ten poems, an even number that causes Vergil's centrally oriented balancing of similar pieces to remain ambiguously off-centre, Calpurnius has seven, clearly divided by subject into two kinds: four rustic poems and three that critics have called court poems, allegorical poems, or, more rightly, political poems whose chief topic is the benefits of the Neronian golden age. The uneven number allows for a precise balancing of similar poems in the two halves of the book. A political poem, a contest poem and a rustic dialogue in the first half have their counterparts in a rustic monologue, a contest poem and a political poem in the latter half. The central poem is political. In devising this order, Calpurnius may well have aimed to remedy what to him seemed defective in Vergil's uncertain symmetry, but the pattern is also well adapted to his own themes.
Renal capsular tumors: the angiographic features.

AbstractFive masses of the renal capsule, which were studied angiographically, demonstrated a typical inward displacement of the renal parenchyma, and prominence and variable displacement of the renal capsular arteries. Benign lesions typically lacked malignant neovascularity and had a sharp interface with the renal parenchyma. The angiographic characterization of renal capsular lesions may help in identification of benign lesions and prevent unnecessary nephrectomy
Assessing dental hygiene clinical competence for initial licensure: a Delphi study of dental hygiene program directors.

PURPOSE The purpose of this study was to describe the best way to determine clinical competence prior to issuing the dental hygiene license. METHODS Directors of dental hygiene programs in the United States, Puerto Rico, and the Virgin Islands were asked to describe the best way to determine clinical competence prior to issuing the dental hygiene license. Three rounds of the Delphi process were used to seek a level of consensus among panel members. A total of 44 directors (19% of the population) from dental hygiene schools participated in at least one round of the study. Sixteen directors participated in all three rounds. Likert scale and ranking questionnaires followed the initial open-ended question. RESULTS A level of consensus was achieved on 47% of the initial statements describing the determination of clinical competence. A list of the top 10 most agreed upon responses to the initial question was generated. Ongoing process evaluations within the accredited dental hygiene program, was suggested as the best determination of clinical competence for dental hygiene licensure. CONCLUSION The findings suggest that dental hygiene clinical competence is best determined throughout a continuum of process and product examinations, rather than in a one-time product evaluation. Accreditation was acknowledged as an important element in standardizing the assessment of clinical competence. Organized dental hygiene should develop a protocol for licensing new dental hygienists and work with state boards of dentistry on its implementation.
Development of a New Single-Molecule Imaging Approach to Measure Turnover Dynamics of Endocytic Proteins

Cells use multi-protein assemblies to carry out a wide variety of biochemical, structural, and mechanical functions. Measuring the timeline of assembly and relative motions of the components can reveal interesting mechanisms of function, especially in highly dynamic mechanical or cytoskeletal structures. More importantly, the turnover of individual components, or exchange of protein molecules with new ones from the cytoplasm, is a key aspect of such structures but is often much more difficult to measure directly. Many assemblies are smaller than the resolution limit of fluorescence microscopy and any sub-structural dynamics can be inferred only through indirect methods or assumed knowledge of a model of the assembly. We have developed a novel single-molecule approach inspired by aspects of fluorescence speckle microscopy, super-resolution microscopy and single particle tracking to directly test important questions of turnover and heterogeneity within cellular assemblies. After labeling only a few molecules of a protein of interest in the cell, we apply super-resolution localization methods to record the positions, trajectories, and lifetimes of individual molecules within an assembly. Here we apply this method to investigate the single-molecule dynamics of several proteins of interest in live fission yeast cells to explore the dynamics of the eisosome (a fungal structure for plasma membrane organization) and the actin machinery in clathrin-mediated endocytosis. Our approach reveals details of the dynamics of these assemblies that have not been directly observable by conventional imaging approaches. We can directly assess heterogeneous behaviors and measure the rate of turnover of components on the timescales of several seconds. This work will enable further exploration of the mechanisms of force production in endocytosis and the method will be broadly applicable to study a variety of other macromolecular assemblies.
Unusual infant eosinophilia: myeloid neoplasm with FGFR1 abnormality.

![Figure][1] An 8-month-old male infant presented with a diffuse sandpaper-like rash, lymphadenopathy, hepatosplenomegaly, fever, tonsillar hypertrophy, frequent infections, and failure to thrive. Complete blood count showed marked leukocytosis (white blood cell count, 34.91 × 109/L;
Formulation and assessment of flamelet-generated manifolds for reacting interfaces

The coupling of heat and mass transfer at the surface of solid or liquid fuels is important when modeling near-surface gasification and combustion processes. Modeling the reacting boundary layer with the use of finite-rate chemistry allows for a highly accurate description of the coupling between the flame and fuel surface, but is not tractable when considering detailed chemical kinetic mechanisms. In this study, simplified unsteady 1D flames with mass blowing are considered for a solid biomass fuel where the flamelet-generated manifold (FGM) method is employed as a model reduction strategy for potential application to multidimensional calculations, such as flame spread over solid materials undergoing pyrolysis and ablation. Two types of FGM are considered. The first are a set of steady-state flames differentiated by their scalar dissipation rate. Steady flamelets have been used extensively in the past for jets, shear-layers, etc. but, their application to solid fuel boundaries is new. Results show that the use of steady flames produce unacceptable errors, with temperature errors in excess of 45%. To avoid these errors, a new methodology for developing an unsteady FGM is presented that accounts for unsteady diffusion effects but, is also independent of surface mass flux. Results using the unsteady FGM greatly reduces errors in temperature with differences that are under 10%.
Selecting Research Participants

This chapter outlines the steps for identifying a sample for a project. Sampling strategies are important for findings and specific strategies can help meet the purpose of a project. Human samples must be treated with care, and required training is expected from each person that engages in such research. This chapter reviews the importance of samples, the various types of samples, and strategies for recruiting and protecting subjects. Ethical issues related to subjects are addressed in this chapter, as well as the importance of inclusion and exclusion criteria and research protocols.
Data structures: an advanced approach using C

A modern treatment of data structures using the C programming language. Emphasizes such programming practices as dynamic memory allocation, recursion, data abstraction, and "generic" data structures. Appropriate for sophomore level data structures courses that use C, taking advantage of the flexibility that C provides. (vs. VanWyck, Korsh/Garrett)
CSR-Kommunikation in der Modebranche

Nachhaltiges Handeln ist fur hessnatur Grundungsimpuls, Unternehmensprinzip und wesentliches Alleinstellungsmerkmal. hessnatur hat das Thema Nachhaltigkeit nicht im Verlauf der Unternehmensentwicklung entdeckt, sondern arbeitet von Beginn an nach diesem Prinzip. Als Heinz und Dorothea Hess 1976 ihr Unternehmen grundeten, hatten sie ein Ziel: Gesunde, schadstofffreie Kleidung fur ihr erstes Kind, den Sohn Matthias. Im konventionellen Handel war Kleidung aus Naturfasern ohne chemische Ausrustungen kaum zu finden. Davon liesen sie sich nicht entmutigen, wurden selbst aktiv und knupften Kontakte zu Lieferanten, die Kleidung nach ihren Vorstellungen fertigen konnten. Diese Idee sprach sich schnell herum und aus den familiaren Anfangen entwickelte sich bald ein erfolgreicher Versandhandel fur Kleidung, Wasche und Accessoires. Seit mehr als 40 Jahren bestimmen die drei Dimensionen nachhaltigen Handelns, Okologie, Okonomie und Soziales, die Unternehmensausrichtung. Dabei ubernimmt der Naturmodepionier Verantwortung uber die gesamte textile Wertschopfungskette, vom Anbau bis zum Kleiderbugel. Mit Naturmaterialien, bevorzugt aus kontrolliert biologischem Anbau (kbA) oder kontrolliert biologischer Tierhaltung (kbT), Rohstoffen naturlichen Ursprungs oder Recyclinglosungen ist hessnatur in der gesamten Breite und Konsequenz des Sortiments Vorreiter fur nachhaltige Mode. Heute steht das Unternehmen mehr denn je fur die Verbindung von Ethik und Asthetik und zeigt, dass Mode und Nachhaltigkeit keinen Widerspruch bedeuten. Mit einer einheitlichen Designhandschrift uber die gesamte Kollektion lost hessnatur diesen Anspruch ein, Passform, Stilistik und Verarbeitungsqualitat eingeschlossen.
The Impact of Project Managers’ Personality on Project Success in NGOs: The Mediating Role of Transformational Leadership:

This study examined the extent to which project managers’ personality determines project success through the mediating mechanism of transformational leadership. The context of the study was nongove...
Imaging Canine Urocystoliths: Detection and Prediction of Mineral Content

The role of survey radiography, contrast radiography, and ultrasonography in the assessment of urocystolithiasis has been primarily one of detection. Information about the radiographic characteristics of uroliths (size, shape, radiopacity, surface characteristics, number detected) for characterization and diagnosis of urocystolithiasis is emerging; however, there are no studies on the accuracy or sensitivity of these techniques. In this article, the intent is to update knowledge about available imaging techniques used in the detection and characterization of urocystoliths based on recent studies designed to evaluate their accuracy in prediction of different urocystoliths mineral content.
Health and Daily Functioning of Older Women Religious

Objectives Women religious in the United States are aging as a population. These women live in a communal setting, eat from the same kitchen, are nulliparous, and have similar access to healthcare. The purpose of this study was to examine the general health and health practices of a modern sample of older women religious. Design Cross-sectional descriptive study. Setting Cleveland Catholic Diocese, Cleveland, Ohio. Participants Older women religious (n = 108), 65 years or older, living independently within the Cleveland Catholic Diocese who could participate in a study interview, undergo a morphometric examination, and complete several questionnaires in English. Measurements Study participants completed a study interview in which their demographic information, medical history, body mass index (BMI), and blood pressure were obtained. Participants completed several questionnaires including the Tilburg Frailty Indicator, Falls Efficacy Scale-International, Lawton Instrumental Activities of Daily Living Scale, Geriatric Depression Scale-Short Form, and the HbL Medication Risk Questionnaire. Results The women in our sample were all white with a mean age of 75.6 years (range = 65-93 y). The vast majority (n = 104 [96%]) had at least a bachelor's degree. Prevalence for chronic diseases was notable for cataracts (60%), hypertension (60%), thyroid disorders (30%), osteoporosis (17%), and diabetes (7%). Nearly half of the sample (n = 48 [44%]) met BMI criteria for obesity, and another 39 women (36%) were overweight. Most women participated in yearly dental examinations (84.5%), eye examinations (79.4%), mammography (84.5%), and pneumovax vaccination (80.4%). Just over half of the women had the recommended colonoscopy (58.8%) and bone density (56.7%) screenings. Twenty women (19%) reported significant frailty, and 38 (35%) reported a significant fear of falling. The majority (80%) would benefit from a discussion about their medications. Conclusion Older women religious experience health issues that could benefit from targeted preventive health education and screening. J Am Geriatr Soc 67:1866-1870, 2019.