cssi/SciSciGPT-SciSciNet huggingface dataset:
Assessment of a Cross‐Disciplinary Domestic Violence Training for Emergency Medicine Residents and Law Students

Objectives: Domestic violence (DV) patients often have complex medical, social and legal issues that challenge assessment, treatment and referral. We designed a brief cross-disciplinary training for emergency medicine residents and upper level law students to determine the baseline level of resident and law student competence in assessment and management of patients with a history of domestic violence. Methods: The study included 23 emergency medicine residents and 28 upper level law students at an urban university. The design included pretest, intervention, and retest with 4 standardized patient assessments. The intervention included for each 2 hours of cross-disciplinary lectures on DV and one joint case-based 2 hour learning session with the medical and legal learners. Communication skills (CSs) were assessed using a validated criterion standard. History taking competence (HX) was assessed with a prespecified checklist of critical elements designed to elicit key medico-legal factors relevant to each case. Data were compared with t tests. Results: 18 (78%) residents and 26 (93%) law students completed the study. Pre-intervention, residents scored 63% (8% standard deviation (SD)) on CS and gathered 71% (13%) of critical HX elements. Law students scored 62% (8%) on CS and gathered 66% (8%) of critical HX elements. Residents (64% (6%)) and law students (63% (6%) showed similar post-intervention CS scores. Both residents (77% (10%), improvement 6%, p = 0.13) and law students (71% (14%), improvement 8%, p = .15) showed modest but non-significant improvement in critical HX gathering. Conclusions: A brief cross-disciplinary training between medical and legal learners demonstrated low baseline scores in DV assessment for both learning groups with modest, but non-significant improvements in gathering of critical HX elements following intervention. Longer didactic training or more focused skill building might improve skills.
Role of instrumented fetal sheep preparations in defining the pathogenesis of human periventricular white-matter injury

Periventricular white-matter injury is the major form of brain injury associated with prematurity and the leading cause of cerebral palsy in survivors of premature birth. Progress in understanding the pathogenesis of periventricular white-matter injury requires the development of animal models that are relevant to the unique physiology of the preterm human brain and that replicate the major neuropathologic features of human injury. The sheep is the most extensively studied true fetal preparation. The neurodevelopment of the preterm sheep fetus (0.65 gestation) is comparable to that of the preterm human between approximately 24 and 28 weeks. The size of the fetal sheep permits chronic instrumentation so that well-defined insults can be studied with reliable measurements of blood flow and metabolism in cerebral white-matter. We review here recent developments in the understanding of the role of cerebral hypoxia-ischemia and vulnerable oligodendrocyte progenitors in the pathogenesis of periventricular white-matter injury in the immature sheep fetus. We focus on recent developments in high-resolution spatially defined cerebral blood flow measurements in utero. We determined ovine white-matter maturation between 90 and 120 days' gestation, as defined by immunohistochemical localization of oligodendrocyte lineage-specific antibodies. There was considerable spatial and temporal heterogeneity in oligodendrocyte maturation in the immature periventricular white-matter. Oligodendrocyte maturation in the 90- to 105-day fetal sheep closely coincided with that of the preterm human during the high-risk period for white-matter injury. Hence, the immature state of the 90- to 105-day fetal periventricular white-matter is an optimal and dynamic developmental window to study the role of cellular-maturational factors in the pathogenesis of white-matter injury. We conclude with a review of the significant advantages of the instrumented fetal sheep to accelerate progress in the translation of preventive therapies for periventricular white-matter injury and cerebral palsy.
An analytical approach for treating background in spectral analysis measurements

Abstract A method of determining the spectral shape of background radiation present in experimental spectra via a mathematical approach is presented. Elements of interest will be subtracted from an experimental spectrum using the linear correlation coefficient across a characteristic peak to determine their contribution. Once all elements of interest are removed, the remainder of the experimental spectrum should represent an approximation of the background. This approximation can then be used in conjunction with library least-squares to determine the background and elemental contributions to the unknown spectrum.
Repeatable and realistic wireless experimentation through physical emulation

In wireless networking research, there has long existed a fundamental tension between experimental realism on one hand, and control and repeatability on the other hand. Hardware-based experimentation provides realism, but is tightly coupled to the physical environment and circumstances under which experiments are carried out. To overcome this, researchers have understandably embraced simulation as a means of evaluation. Unfortunately, wireless simulation is plagued with inherent inaccuracies. To overcome the stark tradeoff between the realism of hardware-based experimentation and the repeatability of simulation-based experimentation, we are developing a wireless emulator that enables both realistic and repeatable experimentation. Unlike previous emulators, our approach simultaneously achieves both a high degree of realism and fine-grained repeatability by leveraging physical layer emulation.
Quality control in steroid hormone receptor assays

This report discusses the sources of variance that can occur in the quantitation of receptors and summarizes how a suitable control program can be established. Variance is defined as the discrepancy in analytical results when assays are performed on the same material.
Customer stress‐relaxation: the impact of music in a hospital waiting room

This study investigated the impact of music on customers, persons waiting for surgery patients, in a hospital’s surgery waiting room; an inherently stressful environment. These persons are customers of the hospital in that they are using the hospital’s services, are typically involved in the decision to use the hospital for the patient’s surgery, and are often responsible for financial payments. In self‐reports from persons using the waiting room, the use of music was related to decreased stress and increased relaxation in comparison to times when no music was utilized. This improved mood state was not, however, correlated with better evaluations by these individuals of the quality of the hospital’s services or of improved perceptions that the hospital was meeting expectations concerning its overall service delivery. These findings contribute to the ongoing research concerning the role of atmospherics or ambience of a service system in customers’ quality/satisfaction evaluations.
Development and factor structure of a brief instrument to assess the impact of community programs on positive youth development: The Rochester Evaluation of Asset Development for Youth (READY) tool.

Abstract Purpose Positive youth development is increasingly recognized as important to the health and well-being of adolescents. We describe the development of a brief, standardized instrument for measuring outcomes and indicators important for youth development evaluation. Additionally, we describe the psychometric properties of these constructs. Methods A coalition of representatives from 12 community organizations, funders, and researchers identified four core outcomes associated with positive youth development likely able to be affected by community-based youth-serving agencies. Items were piloted and field tested to test feasibility and establish face validity with experts and with adolescents. Furthermore, we tested construct reliability using factor analysis to determine how well the items reflected underlying constructs. Results Items representing four empirical constructs were used to survey 389 adolescents. Those who participated in the pilot took an average of 11 minutes to complete the survey. Overall, 24 items loaded on to six discrete factors representing the outcomes of basic social skills, caring adult relationships, and decision-making. When participants under age 13 years were eliminated from the analysis, items were more cohesive, resulting in a five-factor solution with all items loading at .40 or higher. Conclusions The four youth development outcomes identified by community-based youth-serving organizations factor into reliable constructs with acceptable alpha coefficients for adolescents over age 13. A major strength of this youth development outcome measurement is that it has an easy-to-administer format, which allows community-based programs to receive feedback for program improvement, and to track the effectiveness of their programs for funders.
House members as residual claimants: Campaign spending in the 1980s

Through 1992, federal election campaign laws and House rules permit U.S. Representatives holding office on 8 January 1980, to personally claim unspent campaign contributions when they retire, while other House members have to forfeit such sums. These rules provide differential incentives to pre-1980 members to more aggressively seek and yet refrain from spending political contributions than other House members. Regression estimates suggest that the privilege was worth almost $71,700 to the typical pre-1980 House member during the 1987–88 election cycle.
Means-end chains: Connecting products with self

Abstract We conducted a study to explore how two decision situations affected subjects' product knowledge, end-goals, and means—end relationships that were activated for greeting cards. Forty female subjects read a decision scenario to buy either a thinking-of-you card or a wedding card. A paper and pencil laddering task was used to elicit subjects' means—end knowledge structures in the given choice situation. In our conceptualization, the means represent product knowledge or attributes, and the ends represent aspects of consumers' self-knowledge that vary in different situations. Content analysis revealed that the thinking-of-you situation activated receiver-related goals (i.e., “to make her happy”), whereas the wedding situation activated end-goals related to self-expression (i.e., “to express my personality”). Analysis of the means—end linkages revealed that differences in the activated goals affected the meaning of the attributes to which the end-goals were connected. We conclude by discussing the implications of incorporating self into theory and research on means—end chains.
Copper deficiency and hyperlipoproteinemia induced by a tetramine cupruretic agent in rabbits.

The effectiveness of a cupruretic agent,N,N′-bis-(2 amino ethyl)-1,3-propanediamine HCl or 2,3,2-tetramine HCl (TETA), in the induction of copper (Cu) deficiency and the ability of a Cu-deficient diet in the maintenance of the depressed Cu status 10 wk after TETA treatment were examined in this study. In the first experiment, 42 male New Zealand White rabbits, 35 d of age, were randomly divided into three dietary treatments: a copper (Cu)-deficient (2.3 mg Cu/kg diet), a Cu-adequate (13.5 mg Cu/kg diet), and a commercial ratio (21.6 mg Cu/kg diet) group. A single oral dose of 100 mg of 2,3,2-tetramine HCl TETA/kg body wt/d were administered to, half of the rabbits from each treatment group for 10 d while the remaining rabbits were untreated. In the second experiment, 10 similar rabbits were assigned to three treatments: Cu-deficient plus TETA (n=4); Cu-adequate plus TETA (n=3); and Cu-adequate alone (n=3). The rabbits were fed a TETA dose of 100 mg/d for three 4-d periods over 3 wk, and thereafter maintained on the diets for another 10 wk. Rabbits from the first experiment fed Cu-deficient died and treated with TETA demonstrated cardiac hypertrophy and markedly reduced plasma and liver Cu concentrations that indicated that the animals were Cu-deficient. Significant elevations (twofold) in low density lipoprotein (LDL) protein, cholesterol, triglyceride, and apolipoprotein B (apo B) concentrations were observed in TETA treated rabbits fed Cu-deficient diet. In the second experiment, the plasma LDL protein level remained elevated, the plasma Cu level was reduced 45%, and the Cu level of the heart when expressed as μg/g dry tissue was reduced, 10 wk post TETA treatment in rabbits maintained on Cu-deficient diet. Thus, Cu deficiency and hyperlipoproteinemia was rapidly induced by TETA and was still evident 10 wk posttreatment in rabbits maintained on a Cu-deficient died.
Residual Deep Plowing Effects on Irrigation Intake for Pullman Clay Loam

Pullman clay loam (fine, mixed, thermic Torrertic Paleustoll) and related soils predominate in the southern High Plains of the USA. They are slowly permeable but respond to deep tillage with increased irrigation water intake. A one-time deep moldboard plowing to 0.4-, 0.6-, or 0.8-m depths was performed in 1966 to evaluate the inversion and mixing of the slowly permeable Bt1 horizon with the Ap horizon. We hypothesized that these deep tillage effects would still be present after 25 yr. We report irrigation intake effects with 5 yr (four growing seasons) of cropping to winter wheat (Triticum aestivum L.) beginning in 1988. After moldboard plowing to 0.2 m to restore surface tillage layer permeability, residual effects from the 1966 deep plowing caused an average increase in intake of 26% (129-163 mm) for the 0.4-m plow depth, compared with the 0.2-m check, for the first irrigation after tillage from 1988 to 1992. Irrigation intake increased 40% (52 mm) with 0.6-m deep plowing; however, there was no additional increase for 0.8-m plowing. Grain yields increased from 4.2 to 5.0 Mg ha -1 (19%) for the 0.4-m or deeper plowing. The 1966 deep tillage also increased deep soil water storage between the 1- and 2.3-m depths during 1988 to 1992. Water use efficiencies were 8% greater for the deep plowing treatments.
Design and analysis of a 55-kW air-cooled automotive traction drive inverter

The purpose of this study is to determine the thermal feasibility of an air-cooled 55-kW power inverter with SiC devices. Air flow rate, ambient air temperature, voltage, and device switching frequency were studied parametrically by performing transient and steady-state simulations. The transient simulations were based on inverter current that represents the US06 supplemental federal test procedure from the US EPA. The results demonstrate the thermal feasibility of using air to cool a cylindrical-shaped 55-kW SiC traction drive inverter with axial-flow of air. When the inverter model is subject to one or multiple current cycles, the maximum device temperature does not exceed 164°C (327°F) for an inlet flow rate of 270 cfm, ambient temperature of 120°C, voltage of 650 V, and switching frequency of 20 kHz. The results show that the ideal blower power input for the entire inverter with a total inlet air flow rate of 540 cfm is 312 W.
Single incision laparoscopic total abdominal colectomy with ileorectal anastomosis for synchronous colon cancer.

Single incision laparoscopy is currently performed mostly for basic laparoscopic procedures involving single abdominal quadrants. The aim of this case report is to show that single incision laparoscopic techniques can be utilized for complex abdominal laparoscopic procedures with a large target organ and a working space involving all quadrants of the abdominal cavity. A single incision laparoscopic total abdominal colectomy with an ileorectal anastomosis and intraoperative CO2 colonoscopy was performed for a patient with synchronous adenocarcinoma of the cecum and the sigmoid colon. The patient was discharged home on postoperative day 4 and had no immediate postoperative complications. Single incision laparoscopy is feasible for complex colorectal procedures. Some of the techniques used may be adapted further to achieve colonic resection via a natural orifice in the future.
Teaching NeuroImages: Brain air embolism due to YAG laser bronchoscopy.

An 83-year-old man with renal cell carcinoma with lung metastases was admitted with hemorrhage from an endobronchial tumor. He underwent bronchoscopy, and an Nd-YAG laser was used to debulk the tumor. Immediately after, the …
THE STRANGE CROSS-REACTION OF MENADIONE (VITAMIN K3) AND 2,4-DINITROPHENYL LIGANDS WITH A MYELOMA PROTEIN AND SOME CONVENTIONAL ANTIBODIES

To explore the possibility that the affinity of some myeloma proteins for 2,4-dinitrophenyl (DNP) ligands is the consequence of a "strange" (i.e., unexpected) cross-reaction for more natural ligands, a variety of substances (primarily derivatives of purines, pyrimidines, naphthaquinone) were tested for ability to block the binding of [3H]-e-DNP-L-lysine by protein 315, an IgA mouse myeloma protein with high affinity for DNP ligands. The most impressive inhibiting activity was observed with 2-methyl-1,4-napthaquinone (menadione, vitamin K3). The affinity (intrinsic association constant) of protein 315 for menadione was 5 x 105 L/M (at 4°C). Because the same affinity was measured in direct-binding assays (e.g., equilibrium dialysis) and in an indirect one based on the assumption of competitive binding with DNP-lysine, it is likely that menadione and DNP bind at overlapping sites in the protein's combining region. This conclusion is supported by molecular models which reveal some common structural features in these ligands. Hence it is not surprising that antinitrophenyl antibody preparations, raised by conventional immunization procedures (anti-2,4-DNP; anti-2,6-DNP; anti-2,4,6-TNP) also bind menadione with considerable affinity. As with DNP ligands, when menadione binds to protein 315 or to conventional antinitrophenyl antibodies, some of the protein's tryptophan fluorescence is quenched, there is a change in the ligand's absorption spectrum (hypochromia and/or red shift), and the binding is temperature-dependent (exothermal).
Software as a Service: Configuration and Customization Perspectives

Software as a service (SaaS) provides software application vendors a Web based delivery model to serve big amount of clients with multi-tenancy based infrastructure and application sharing architecture so as to get great benefit from the economy of scale. Though SaaS application is usually developed with highly standardized software functionalities to serve as many clients as possible, many clients still ask for function variants according to their unique business needs through easy configuration and customization. Due to the subscription based model, SaaS vendors need take a well designed strategy to enable self serve configuration and customization by their customers without changing the SaaS application source code for any individual customer. In this paper, we will explore the configuration and customization issues and challenges to SaaS vendors, clarify the difference between configuration and customization. A competency model and a methodology framework have been developed to help SaaS vendors to plan and evaluate their capabilities and strategies for service configuration and customization.
Amplification of Nucleic Acids by Polymerase Chain Reaction (PCR) and Other Methods and their Applications

The in vitro replication of DNA, principally using the polymerase chain reaction (PCR), permits the amplification of defined sequences of DNA. By exponentially amplifying a target sequence, PCR significantly enhances the probability of detecting target gene sequences in complex mixtures of DNA. It also facilitates the cloning and sequencing of genes. Amplification of DNA by PCR and other newly developed methods has been applied in many areas of biological research, including molecular biology, biotechnology, and medicine, per- mitting studies that were not possible before. Nucleic acid amplification has added a new and revolutionary dimension to molecular biology. This review examines PCR and other in vitro nucleic acid amplification methodologies - examining the critical parameters and variations and their widespread applications - giving the strengths and limitations of these methodologies.
Fabrication of three-dimensional hierarchical nanostructures using template-directed colloidal assembly.

Optical effects in template-directed colloidal assembly are explored to fabricate microscale patterns with integrated three-dimensional (3D) nanostructures. This method allows the patterning of periodic nanostructures in arbitrarily designed regions by controlling particle assembly and light illumination. Using both “bottom-up” and “top-down” methods, this approach enables low-cost fabrication of hierarchical devices.
Coronary heart disease and NIDDM in Japanese-Americans

Glucose intolerance is associated with increased risk of coronary heart disease (CHD) in Japanese-Americans, especially in men. Intra-abdominal fat, assessed by computed tomography, is increased in those with both NIDDM and CHD. Increased intra-abdominal fat (visceral adiposity) with CHD is independent of NIDDM or impaired glucose tolerance. The association between NIDDM and CHD may be explained by the association of each of these conditions with visceral adiposity. However, hyperinsulinemia is associated with CHD only in the presence of diabetes, whereas triglyceride levels are elevated with CHD independent of glucose tolerance category. These findings suggest that factors other than insulin levels, such as lipids, may mediate the relationship between visceral adiposity and CHD. Moreover, these relationships are influenced by gender.
Understanding Planetary Rings

The rings in the solar system and the mathematical and physical approaches to understanding them are described. The variety of ring phenomena revealed in recent years from space and earth-based observations is emphasized. Ideas for the recent history of rings are examined in some detail. The major open questions and future opportunities to learn about planetary rings are discussed.
Empirically Based Ground Truth Criteria for Seismic Events Recorded at Local Distances on Regional Networks with Application to Southern Africa

Wepresentanewapproachtoobtainingempiricallybased(EB)criteriafor estimating the epicentral location accuracy (i.e., ground truth, GT) of seismic events recorded at local distances on a regional network. The approach has been developed usinga jackknife resampling method appliedto carefully pickedPgphasearrivaltimes for GT reference events from several South African gold mines. The events were well recorded locally by Southern African Seismic Experiment (SASE) stations within the Archean Kaapvaal craton, an area of relatively simple crustal structure. The region- specific criteria obtained specify an EBGT395% level of epicentral accuracy if events are recorded on eight or more stations at distances less than the Pg=Pn crossover (215 km) when the stations have a primary azimuthal gap <202 degrees. In addition, when nine or more stations are used for event location and one of them is within 79 km of the event, we find that a focal depth accuracy of 4 km at the 95% confidence level can be obtained and that an accuracy of 6 km can be obtained if eight stations are used. This result illustrates that GT criteria commonly applied to global event catalogs can be relaxed if an accurate velocity model and carefully picked phase-arrival times are used for event locations. Consequently, it is likely that additional events can be added to GT compilations by developing EBGT criteria for other regional networks and using them to identify candidate GT events. For example, the EBGT criteria developed in this study, when applied to the SASE seismicity catalog, yields 10 new GT events.
Letter by Ashrani Regarding Article, “Birth Weight Is a Significant Risk Factor for Incident Atrial Fibrillation”

To the Editor: I read with great interest the article, “Birth Weight Is a Significant Risk Factor for Incident Atrial Fibrillation,”1 in which Conen et al noted that rising birth weight was significantly …
Sweet Potato as an Ingredient of Yeast-Raised Doughnuts

Jewel sweet potatoes (SP) were prepared as flour and puree of baked and steam-cooked roots. SP replaced 0, 7, 14, and 21% of the wheat flour in a recipe for yeast-raised doughnuts. Composition of doughnuts was apparently affected by type and amount of SP. Caloric content ranged from 6.32–7.03 Kcal/g dry material. Texture and specific volume of doughnuts were affected by SP. Crumb color of doughnuts with SP was yellow-orange. Six quality attributes tested by a panel were affected by SP, but for the most part, overall quality of the doughnuts was not lowered.
Optimal Comparable Selection and Weighting in Real Property Valuation

This paper formalizes certain aspects of the sales comparison approach to valuation that heretofore have been quite ad hoc. Specifically, it applies statistical theory to decisions about how many comparables to select, what the criteria for comparable selection should be, and how the proper weights for each adjusted value estimate can be determined such that the final value estimate is both unbiased and of minimum variance. Several results are derived that run counter to conventional practice; for example, it may not always be optimal to consider first the “best” comparables because of a lack of independence among their adjusted value estimates. Furthermore, it is always desirable to consider more comparables (regardless of how “bad”) so long as their adjusted value estimates are optimally weighted in the final value estimate. Finally, weights usually selected for “inferior” comparables are typically too small. A final exercise empirically applies the methodology to a sample of sales.
THE M26 HOTSPOT OF SCHIZOSACCHAROMYCES POMBE STIMULATES MEIOTIC ECTOPIC RECOMBINATION AND CHROMOSOMAL REARRANGEMENTS

Homologous recombination is increased during meiosis between DNA sequences at the same chromosomal position (allelic recombination) and at different chromosomal positions (ectopic recombination). Recombination hotspots are important elements in controlling meiotic allelic recombination. We have used artificially dispersed copies of the ade6 gene in Schizosaccharomyces pombe to study hotspot activity in meiotic ectopic recombination. Ectopic recombination was reduced 10-1000-fold relative to allelic recombination, and was similar to the low frequency of ectopic recombination between naturally repeated sequences in S. pombe. The M26 hotspot was active in ectopic recombination in some, but not all, integration sites, with the same pattern of activity and inactivity in ectopic and allelic recombination. Crossing over in ectopic recombination, resulting in chromosomal rearrangements, was associated with 35-60% of recombination events and was stimulated 12-fold by M26. These results suggest overlap in the mechanisms of ectopic and allelic recombination and indicate that hotspots can stimulate chromosomal rearrangements.
Stability Measurements of a Superconductor Cooled By a Two-Dimensional Channel of Helium II

This report presents measurements on the stability of a He II cooled superconductor. The conductor is helically wound in a phenolic coil support and is cooled by a channel of He II which allows for heat transfer in two dimensions. Stability is measured by recovery of the superconducting state following a transient burst of heat. The data also allows one to measure normal zone propagation velocities and temperature profiles at various times. Currents in the conductor range from 0 to 5 kA with background magnetic field ranging from 0 to 11 tesla. Descriptions of stability boundaries are given in terms of maximum energy bursts from which the conductor recovers as a function of transport current, channel size and background field. Comparisons of the data with an analysis of stability in a one-dimensional channel are shown to be useful. This experimental configuration is intended to model some aspects of a superconducting magnetic energy storage system.
Bioenergy from Coastal bermudagrass receiving subsurface drip irrigation with advance-treated swine wastewater.

Coastal bermudagrass (Cynodon dactylon L.) may be a potentially important source of bio-based energy in the southern US due to its vast acreage. It is often produced as part of a waste management plan with varying nutrient composition and energy characteristics on fields irrigated with livestock wastewater. The objective of this study was to determine the effect of subsurface drip irrigation with treated swine wastewater on both the quantity and quality of bermudagrass bioenergy. The treated wastewater was recycled from an advanced treatment system and used for irrigation of bermudagrass in two crop seasons. The experiment had nine water and drip line spacing treatments arrayed in a randomized complete block-design with four replicates. The bermudagrass was analyzed for calorific and mineral contents. Bermudagrass energy yields for 2004 and 2005 ranged from 127.4 to 251.4 MJ ha 1 . Compared to irrigation with commercial nitrogen fertilizer, the least biomass energy density was associated with bermudagrass receiving treated swine wastewater. Yet, in 2004 the wastewater irrigated bermudagrass had greater hay yields leading to greater energy yield per ha. This decrease in energy density of wastewater irrigated bermudagrass was associated with increased concentrations of K, Ca, and Na. After thermal conversion, these compounds are known to remain in the ash portion thereby decreasing the energy density. Nonetheless, the loss of energy density using treated effluent via SDI may be offset by the positive influence of these three elements for their catalytic properties in downstream thermal conversion processes such as promoting a lesser char yield and greater combustible gas formation. Published by Elsevier Ltd.
Education and Personality Variables Related to Prejudice

(1962). Education and Personality Variables Related to Prejudice. The Journal of Social Psychology: Vol. 58, No. 2, pp. 269-275.
Lost and Mastermind Narration

ABC’s Lost is indicative of a recent trend in television programming that exploits seriality, information multiplicity and real virtuality. While these aesthetic innovations have arguably facilitated the franchising of this and other programs, it has also created several textual problems around the issues of canon, authority and narration. In this article, I illustrate how Lost uses the strategies of what I call mastermind narration to rearticulate this imperiled textual authority. The strategies of this tendency include the use of repeated subject matter, particularly confidence tricks, and the patterning of textual form, particularly through shifting the narrational valence of series flashbacks.
Using the PATHOS questionnaire for screening sexual addiction among college students: A preliminary exploration

Researchers posit that sexual addiction often develops in young adulthood (Goodman, 2005), the time when many individuals are in college. The PATHOS screening questionnaire (Carnes et al., 2012) may be a helpful resource for counselors working with collegiate populations to identify those in need of further assessment for sexual addiction. We collected data from 379 undergraduate students and found that 21.2% of males and 6.7% of females endorsed 3 or more items on the PATHOS, suggesting a need for additional assessment. We discuss implications and limitations of these findings and highlight the need for additional research on college populations.
Shared resource matrix methodology: an approach to identifying storage and timing channels

Recognizing and dealing with storage and timing channels when performing the security analysis of a computer system is an elusive task. Methods for discovering and dealing with these channels have mostly been informal, and formal methods have been restricted to a particular specification language. A methodology for discovering storage and timing channels that can be used through all phases of the software life cycle to increase confidence that all channels have been identified is presented. The methodology is presented and applied to an example system having three different descriptions: English, formal specification, and high-order language implementation.
Weakening Resistance: Progress Toward the Low Back Merger in New York State

This paper examines the status of the low back caught-cot merger in Upstate New York. Most of this region is subject to the Northern Cities Shift (NCS) and therefore, according to Labov, Ash, and Boberg (2006), ostensibly “resists” the spread of this merger. It is found that the phonology of this region is indeed trending toward the merger in apparent time, in terms of both phonetic distance between the two phonemes and speakers' explicit judgments. It is argued that the fronting of the cot vowel in the NCS region is not sufficient to withstand the spread of the merger because fronting a low vowel is a “reversible” sound change (Labov, 2010). It is further argued that the expansion of a merger to new communities may take place indirectly, through launching a sound change in the direction of merger rather than causing merger to take place immediately in the new community.
PARALYTIC DISLOCATION AT THE HIP IN POLIOMYELITIS

A comparison of twenty-six paralytic dislocations of the hip with seventy-five severely paralyzed hips which did not dislocate reveals the fact that no definite type of paralysis was responsible for the dislocation, but that dislocation was most frequent in hips with strong flexors, adductors, and internal rotators and weak extensors, abductors, and external rotators. Of the above muscle groups the abductors appeared to be the most important in maintaining the stability of the hip as we had no cases in which dislocation occurred in the presence of good abductors. A study of the x-rays of these cases revealed the fact that in paralytic hips which had dislocated the acetabulum was poor and severe coxa valga was usually present. However, it is to be emphasized that these deformities were probably the result of the paralysis and dislocation rather than the cause, as we do not believe that there were any congenital abnormalities in these cases. We were impressed by the fact that nearly all of the hips which dislocated presented a definite deformity. As any severely paralyzed hip is liable to dislocate, we believe that the prevention of deformities is especially important in these cases. We were further impressed by the fact that the deformities were not always the direct result of muscle imbalance, but in many cases seemed to have been the result of habitual posture. Consequently, we believe that patients with severely paralyzed hips should spend much of their time with the hips in a position of extension and abduction and external rotation. Operative treatment should be considered in those cases in which conservative treatment has failed or in which there is no reasonable hope that conservative treatment (that is, correction of deformities and maintenance of abduction) will lead to a cure. Contra-indications to operation are such poor general condition that the operation would be unusually dangerous, and such extensive paralysis that even with a stable hip it would not be possible for the patient to walk on crutches and braces. The operation recommended is the shelf operation and we believe that an accurate placing of the shelf is more important than its size, as we have found small shelves just as efficient as large ones.
State Damage Caps and Separation of Powers

In 2010, the Illinois Supreme Court invalidated certain statutory caps on noneconomic damages in medical cases because they “unduly” infringed “upon the inherent power of the judiciary.” Such judicial authority originated within the separation of powers clause of the Illinois Constitution. The caps were deemed to “encroach” on the judiciary’s “sphere of authority” because they impeded “the courts in the performance of their function.” Elsewhere, American state statutory damage caps have also been challenged on state constitutional separation of powers grounds. These challenges include settings where the caps operate for nonmedical cases and where the limits extend beyond noneconomic damages. Given state constitutional diversity, are there core separation of powers principles guiding all American state statutory damage caps? If so, do they apply similarly to all forms of damage caps? With or without such core principles, are there other doctrines, not involving individual rights, that better speak to damage caps? The paper first explores the Illinois precedents on damage caps and separation of powers. Then it examines other state precedents, where it finds the controversies usually involve allocations of civil procedure lawmaking powers. It observes that caps on “statutory causes of action” or during “special proceedings” are often treated differently, as are caps on punitive damages and caps that operate in alternative public forums like administrative agencies. The paper concludes that separation of powers analyses should usually be replaced in damage cap cases with judicial rulemaking analyses. It finds no core principles within state constitutional separation of powers provisions that implicate damage caps. Interstate differences in constitutional allocations of procedural rulemaking authority (and, at times, of justiciable matters) should be recognized more often. This last observation has implications beyond damage caps. Judicial/legislative tensions elsewhere, as with evidence privileges, should also be explored with judicial rulemaking analyses.
Abstract PR05: Targeting of CDK7 inhibits super-enhancer-associated oncogenic programs in MYCN-amplified tumor cells

The MYC oncoproteins are thought to stimulate tumor cell growth and proliferation through amplification of gene transcription, a mechanism that has thwarted most efforts to inhibit MYC function as potential cancer therapy. Using a novel covalent inhibitor of cyclin-dependent kinase 7 (CDK7) to disrupt the transcription of amplified MYCN in neuroblastoma cells, we demonstrate downregulation of the oncoprotein with consequent massive suppression of MYCN-driven global transcriptional amplification. This response translated to significant tumor regression in a mouse model of high-risk neuroblastoma, without the introduction of systemic toxicity. The striking treatment selectivity of MYCN-overexpressing cells correlated with preferential downregulation of super-enhancer-associated genes, including MYCN and other known oncogenic drivers in neuroblastoma. These results indicate that CDK7 inhibition, by selectively targeting the mechanisms that promote global transcriptional amplification in tumor cells, would be useful therapy for cancers that are driven by MYC or its family members. Citation Format: Edmond Chipumuro, Eugenio Marco, Camilla L. Christensen, Nicholas Kwiatkowski, Tinghu Zhang, Clark M. Hatheway, Brian J. Abraham, Bandana Sharma, Caleb Yeung, Abigail Altabef, Antonio Perez-Atayde, Kwok-Kin Wong, Guo-Cheng Yuan, Nathanael S. Gray, Richard A. Young, Rani E. George. Targeting of CDK7 inhibits super-enhancer-associated oncogenic programs in MYCN-amplified tumor cells. [abstract]. In: Proceedings of the AACR Special Conference on Myc: From Biology to Therapy; Jan 7-10, 2015; La Jolla, CA. Philadelphia (PA): AACR; Mol Cancer Res 2015;13(10 Suppl):Abstract nr PR05.
Thomas M. Cooley and “Laissez-Faire Constitutionalism”: A Reconsideration

TI? HOMAS M. COOLEY, nineteenth-century judge, first chairman of the Interstate Commerce Commission, and author of important legal treatises, particularly the Treatise on the Constitutional Limitations Which Rest upon the Legislative Power of the States of the American Union, published in 1868, merits an historical reputation different from the one he has acquired.' Generally viewed as a zealous advocate of the judicial protection of property rights, Cooley is described by Clyde Jacobs as "the principal contributor to the cause of constitutional laissez faire in the era following the Civil War. . . . Benjamin Twiss remarks that Cooley's treatise supplied laissez-faire capitalism with a legal ideology "'almost as a direct counter to the appearance a year earlier of Karl Marx's Das Kapital"; and Marver Bernstein compares him to Supreme Court Justice David Brewer in his observation that "Cooley, like Brewer, regarded the judges as the spokesmen for the principle of the unfettered rights of property and as protectors of the status quo against the threat of popular power."3 A reconsideration of these assessments is needed not merely to do justice
A multi-criteria, network analytic approach to war game participant selection:

A critical component of the military war game planning process is selecting who should participate, as these participants heavily influence war game outcomes. These outcomes directly impact both strategic and operational decision-making and defense planning, shaping both future defense policy and budget. In this paper, we propose a novel team selection algorithm and decision-support tool combining methods from multiple criteria decision analysis and network analytics to select and visualize a group of war game participants. This method accounts for the diverse requirements of the decision-maker. The results are not only applicable to war games, but also to any team selection domain, such as employee hiring and college admissions.
DETECTION OF AN EDGE NOTCH DEFECT BY USING A SINGLE MODE BASED METHODS

Reliable damage and effective damage detection has a significant role for utilization of the composite materials in structural applications. This paper is addressed to the problem of developing a damage detection technique for many damage occurring in a given structures is based on experimentally identified data and mathematical relationships. The mathematical expressions relate the natural frequency changes and the modes of the undamaged structure and the damaged structure containing damages at different locations. The curvature mode is selected in this method because of its sensitivity to the presence of the damage and the localized information that the curvature can provide. Damages are considered as point damages and the effects of the damage on both the stiffness loss and mass loss at each notch location are considered. Experiments are designed and conducted to validate the theoretical developments.
Criteria for Predicting the Formation of Single-Phase High-Entropy Alloys

High-entropy alloys are a new class of materials that have been shown to be strong, ductile, and corrosion-resistant. Ensembles of viable alloys are systematically isolated using density-functional theory.
Characteristics of Nonstationary Response of Linear Systems

A new formulation for the statistics of the response of linear systems to nonstationary excitation is developed. Both the process and its envelope are examined and exact statistics are determined for the general linear systems subjected to modulated white-noise input. Then, the important case of oscillator systems is studied, and by use of functional operator concepts, approximations are obtained for the response statistics. These approximations are based on well-known stationary statistics, are simple in form, and provide meaningful insight into the characteristics of nonstationary response.
The relationship of the corpus luteum and the endometrium in infertile patients

A group of 50 females undergoing an infertility work-up had measurements of serum progesterone levels in all cases, endometrial sampling in 49, and biopsy of a grossly identifiable corpus luteum in 42 cases. Of the 41 cases with three parameters available for study, 39 had correlations of all three parameters. The remaining nine cases had two of three parameters available for study. Of these, three showed a secretory endometrium but absent corpus luteum and an anovulatory progesterone level, and a patient showing a proliferative-phase endometrium at the same time had an ovulatory progesterone level and a postovulatory corpus luteum. The evidence presented suggests that, among the three parameters tested, the progesterone level as a noninvasive procedure serves as a good index of ovulation 92% of the time, and occasionally endometrial histologic sampling does not necessarily reflect ovarian function.
Radical transpubic prostatectomy

AbstractRemoval of an adequate wedge of symphysis pubis provides considerably improved exposure for radical prostatectomy. It is safer to remove the symphysis subperiosteally and to transect the bone with an oscillating bone saw or osteotome. The transpubic approach to radical prostatectomy affords the urologist the advantages of 1) early direct ligation of the dorsal vein, 2) reduced incidence of injury to the external urethral sphincter and subsequent urinary incontinence owing to visualization of the urogenital diaphragm, 3) simplified urethrovesical anastomosis and 4) increased opportunity for maintenance of potency by protecting the pelvic nerve plexus as they course in the lateral vascular pedicles.
Stochastic Neural Networks for Modelling Random Processes from Observed Data

Most Artificial Neural Networks that are widely used today focus on approximating deterministic input-output mapping of nonlinear phenomena, and therefore, they can be well trained to represent the average behaviour of a nonlinear system. However, most natural phenomena are not only nonlinear but also highly variable. Deterministic neural networks do not adequately represent the variability observed in the natural settings of a system and therefore cannot capture the complexity of the whole system behaviour that is characterised by noise. This chapter implements a class of neural networks named Stochastic Neural Networks (SNNs) to simulate internal stochastic properties of natural and biological systems. Developing a suitable mathematical model for SNNs is based on the canonical representation of stochastic processes by means of Karhunen-Loeve Theorem. In the implementation of this mathematical formulation for modelling nonlinear random processes from observed data, SNN is represented as a network of embedded deterministic neural networks, each representing a significant eigenfunction characterised by data, juxtaposed with random noise represented by White noise characterised by the corresponding eigenvalues. Two successful examples, including one from biology, are presented in the chapter to confirm the validity of the proposed SNN. Furthermore, analysis of internal working of SNNs provides an in-depth view of how SNNs work giving meaningful insights.
Kansas River Valley Experiment Field

The Kansas River Valley Experiment Field was established to study management and effective use of irrigation resources for crop production in the Kansas River Valley (KRV). The Paramore Unit consists of 80 acres located 3.5 miles east of Silver Lake on U.S. Highway 24, then 1 mile south of Kiro, and 1.5 miles east on 17th street. The Rossville Unit consists of 80 acres located 1 mile east of Rossville or 4 miles west of Silver Lake on U.S. Highway 24.