cssi/SciSciGPT-SciSciNet huggingface dataset:
Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma

Background RRM1 and ERCC1 overexpression has been extensively investigated as potential predictive markers of tumor sensitivity to conventional chemotherapy agents, most thoroughly in lung cancer. However, data in pancreatic cancer are scarce.
Modelling the effect of the antimicrobial tylosin on the performance of an anaerobic sequencing batch reactor

A laboratory-scale anaerobic sequencing batch reactor (ASBR) was fed a synthetic wastewater containing glucose to study the effects of the antimicrobial tylosin on treatment performance. Measurements of methane, volatile fatty acids, and COD concentrations suggested that the addition of 1.67 mg/L and 167 mg/l of tylosin to the synthetic wastewater inhibited propionate oxidizing syntrophic bacteria and aceticlastic methanogens. The latter is presumed to be an indirect effect. A modified version of the IWA Anaerobic Digestion Model No. 1 (ADM1) with extensions for microbial storage and hydrolysis of reserve carbohydrates, and tylosin liquid–solid mass transfer and inhibition adequately described the dynamic profiles observed in the ASBR.
Molecular/Polymeric Magnets

Abstract The discovery of a transition at 4.8K to a three-dimensional ferromagnetic state in the molecular electron transfer salt [FeCp*2][TCNE] and the recent report of ferrimagnetism in the molecular based V(TCNE)x'Y(CH 2Cl2) adds magnetism to the list of cooperative phenomena now possible in molecular/organic/polymer materials. In this report we review our progress in the study of molecular/polymeric materials that feature a magnetic ground state with a net moment, present a brief discussion of the development of magnetic exchange in these molecular based magnets, and summarize magnetic phenomena in these systems. Emphasis is placed on recent developments in the high Tcmolecular magnet systems including the treatment of their magnetic behavior within the framework of a correlated spin glass (CSG)/ferrimagnet with wandering axis (FWA) formalism. The central role of the relative magnitudes of magnetic exchange, randomness in magnetic exchange, magnetic anisotropy, and randomness in magnetic anisotropy is...
Spatiotemporal dynamics of optogenetically induced and spontaneous seizure transitions in primary generalized epilepsy.

Transitions into primary generalized epileptic seizures occur abruptly and synchronously across the brain. Their potential triggers remain unknown. We used optogenetics to causally test the hypothe...
Structure-property correlations in nanocrystalline AlZr alloy composites

A study of the structure, grain size stability and Vickers microhardness of nanocrystalline aluminum-zirconium alloy composites was conducted. Samples were synthesized by the inert gas condensation process with electron beam evaporation. Transmission electron microscope examinations of the samples were performed at room and elevated temperatures. The behavior of the microstructures of the samples with time and temperature was investigated as a function of specimen composition. Vickers microhardness data were evaluated at room temperature in as-produced and polished compacted specimens. The local chemical composition of individual microhardness indents and average values of the grain size and porosity level were determined for a number of samples. Correlations among these microstructural variables and hardness were determined using multiple regression techniques.
Long-Term Results of Arterial Bypass Surgery for Impotence Secondary to Segmental Vascular Disease

AbstractPurpose: We evaluated the long-term results of arterial bypass surgery in impotent men carefully selected for nonatherosclerotic arterial vascular disease.Materials and Methods: During a 7-year period only 11 of 1,352 impotent men (0.8 percent) were selected as ideal candidates for arterial vascular surgery. Initial evaluation included history, physical examination and a screening pharmacological erection test. Duplex ultrasonography was performed in patients who failed to respond adequately to pharmacological stimulation and were believed to be potential candidates for vascular surgery. Further evaluation included formal nocturnal sleep laboratory testing, dynamic infusion cavernosometry and arteriography. Dorsal artery bypass was performed in 9 patients and arterialization of the deep dorsal vein was done in 2.Results: Average followup was 50 months (range 12 to 84). Initial followup duplex ultrasonography revealed a significant increase in cavernous artery peak systolic blood flow velocity (p l...
Deuteronomy 12 and the Law of the Central Sanctuary noch einmal

AbstractCritiques the recent attempt by Frederick E. Greenspahn to call into question the interpretation of Deut 12 as instituting cult centralization. The paper first considers Greenspahn’s argument that the definite article in the phrase “the place” at Deut 12:5 (and 12:14) is a generic article. The paper also critiques Greenspahn’s assumption that the theory of cult centralization is narrowly based upon a misreading of the definite article at Deut 12:5 (and 12:14). On the contrary, it is argued here that the theory is more broadly dependent on internal data of the chapter and external connections with other portions of the Pentateuch.
Determination of the Viscoelastic Properties of Polymer Films Using a Compensated Phase-Locked Oscillator Circuit

Using a combination of the quartz crystal microbalance and a corresponding physical model for the compound resonator, the viscoelastic properties of polymer films have been studied. By using a compensated phase-locked oscillator system, both resonant frequency and resistance (motional resistance of the Butterworth−Van Dyke equivalent circuit) can be measured simultaneously. The behavior of resistance as a function of film thickness or corresponding frequency shift provides a means not only for quantitatively determining the shear viscosity and elastic modulus of films but also for qualitatively comparing various systems. The physical model is extended to include four layers for describing dissolving/swelling films that form an energy-dissipative, interfacial layer. If the underlying film is rigid and acoustically thin, then the four-layer case can be reduced to a simplified three-layer description.
Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction

The adipocyte-derived hormone adiponectin promotes metabolic and cardiovascular health. Circulating adiponectin increases in lean states such as caloric restriction (CR), but the reasons for this paradox remain unclear. Unlike white adipose tissue (WAT), bone marrow adipose tissue (MAT) increases during CR, and both MAT and serum adiponectin increase in many other clinical conditions. Thus, we investigated whether MAT contributes to circulating adiponectin. We find that adiponectin secretion is greater from MAT than WAT. Notably, specific inhibition of MAT formation in mice results in decreased circulating adiponectin during CR despite unaltered adiponectin expression in WAT. Inhibiting MAT formation also alters skeletal muscle adaptation to CR, suggesting that MAT exerts systemic effects. Finally, we reveal that both MAT and serum adiponectin increase during cancer therapy in humans. These observations identify MAT as an endocrine organ that contributes significantly to increased serum adiponectin during CR and perhaps in other adverse states.
Improved insulin sensitivity with calorie restriction does not require reduced JNK1/2, p38, or ERK1/2 phosphorylation in skeletal muscle of 9-month-old rats.

Calorie restriction [CR; ∼40% below ad libitum (AL) intake] improves the health of many species, including rats, by mechanisms that may be partly related to enhanced insulin sensitivity for glucose...
Obesity and workplace traumatic injury: does the science support the link?

Objective: To explore whether obesity is associated with non-fatal traumatic occupational injury. Design: Systematic literature review. Methods: The peer-reviewed literature was searched from 1 January 1980 to 31 December 2005 for studies on the risk of overweight and obesity on non-fatal traumatic occupational injuries among non-office employees. The search was conducted using Medline, eLCOSH, NIOSHTIC-2, CINAHL, PsycLit, and OSH-ROM. Studies were excluded that focused on military populations, chronic/repetitive workplace injuries, back pain, only height as a risk factor, or were not written in English. Results: The search identified only 12 studies. The risk of injury for obese versus non-obese employees overall was slightly increased, although many of the estimates were not statistically significant. In studies in which increased risk estimates were shown, there was limited exploration of the mechanism of obesity-related injury, but the influence of chronic disease, fatigue or sleepiness, ergonomics, and physical limitations were most often hypothesized. Discussion: With the current growing prevalence of obesity worldwide, more research is needed to better establish its impact on workplace injuries and lost work time. Studies are needed that use large diverse samples, advanced statistical methods, and control for potential confounders, and explore issues related to temporality. Gaining a better understanding of how obesity influences workplace injury may foster the development of interventions that address weight, while still emphasizing the important environmental and sociocultural risk factors for injury.
Right and left ventricular wall deformation patterns in normal and left heart hypoplasia chick embryos

The vertebrate embryonic ventricle transforms from a smooth-walled single tube to trabeculated right ventricular (RV) and left ventricular (LV) chambers during cardiovascular morphogenesis. We hypo...
Blue-ringed octopus (Hapalochlaena sp.) envenomation of a 4-year-old boy: A case report

Introduction. The blue-ringed octopus (Hapalochlaena sp.) is a small animal, which can inject a toxin that produces a respiratory arrest within minutes. This envenomation is a rare occurrence with very few reported outcomes in children. Case report. A 4-year-old boy was bitten by a blue-ringed octopus (Hapalochlaena sp.) whilst playing at a popular beach in Queensland, Australia. Within ten minutes of the bite, he had vomited three times, lost the ability to stand and complained of blurred vision. An ambulance was called by the time he presented to the local emergency department (20 minutes after the bite) he had acute and progressive skeletal muscle weakness. He was intubated, ventilated, and transferred to a pediatric intensive care unit for specialized supportive care. He was ventilated for a total of 17 hours with spontaneous muscular activity returning at around 15 hours from envenomation. Discussion. If not treated appropriately the bite of this small and innocuous looking animal could have lead to death within minutes. Conclusion. This case report serves as a reminder of how appropriate treatment can ensure discharge from hospital with no long-term consequences. It also highlights the importance of education for beach goers and in particular parents to prevent exposure of tetrodotoxin to children.
Explicit energy calculation for a charged elliptical plate

Potential problems for thin elliptical plates are solved exactly with emphasis on computation of the electrostatic energy. Expansions in terms of Jacobi polynomials are used.
Neighborhood Diversity: Social Change, Ambiguity, and Fair Housing since 1968

: More than a generation after the Civil Rights Act of 1968, fair housing remains an ambiguous and unattained goal in the United States. Entrenched opposition, weakness in the original legislation, racial preferences, and division among proponents help to explain this situation. The author examines the latter two factors and identifies the role of historical change in the persisting weakness of fair housing. Through an analysis of the prointegration movement, he argues that demographic and social change since 1968 have eroded support among both whites and blacks for integration and open housing and exacerbated divisions among proponents of fair housing.
The Use of Structural Equation Modeling in Counseling Psychology Research

Structural equation modeling (SEM) has become increasingly popular for analyzing data in the social sciences, although several broad reviews of psychology journals suggest that many SEM researchers engage in questionable practices when using the technique. The purpose of this study is to review and critique the use of SEM in counseling psychology research regarding several of these questionable practices. One hundred five studies from 99 separate articles published in the Journal of Counseling Psychology between 1987 and 2003 were reviewed. Results of the review indicate that many counseling psychology studies do not engage in various best practices recommended by SEM experts (e.g., testing multiple a priori theoretical models or reporting all parameter estimates or effect sizes). Results also indicate that SEM practices in counseling psychology seem to be improving in some areas, whereas in other areas no improvements were noted over time. Implications of these results are discussed, and suggestions for ...
A classification approach for power distribution systems fault cause identification

Power distribution systems play an important role in modern society. When distribution system outages occur, fast and proper restorations are crucial to improve the quality of services and customer satisfaction. Proper usages of outage root cause identification tools are often essential for effective outage restorations. This paper reports on the investigation and results of two popular classification methods: logistic regression (LR) and artificial neural network (ANN) applied on power distribution fault cause identification. LR is seldom used in power distribution fault diagnosis, while ANN has been extensively used in power system reliability researches. This paper discusses the practical application problems, including data insufficiency, imbalanced data constitution, and threshold setting that are often faced in power distribution fault cause identification problems. Two major distribution fault types, tree and animal contact, are used to illustrate the characteristics and effectiveness of the investigated techniques.
Middle Level Writing Programs: What Works and Why.

What makes a middle level writing program a success? This writer undertook a two-year study of middle level classrooms to answer that ques tion. His findings are reported here.
Effect of taxi information system on efficiency and quality of taxi services

In many major metropolitan areas, taxi services have played an important role as a semipublic transportation mode without public support. However, there has not been much modeling effort-despite the importance of taxis in urban transportation systems-mainly because of the difficulty in modeling taxi drivers' behavior. This study models a taxi service system in urban areas, taking into account taxi drivers' knowledge of the transportation network built from their day-to-day experience. Passenger-seeking behavior by taxi drivers is modeled on the basis of their expected travel time and expected waiting time. The model considers the stochastic and dynamic transportation network and various levels of network knowledge on the part of drivers. This modeling approach provides flexibility in modeling the characteristics of taxi operation as well as understanding how taxi drivers' capability evolves. The study analyzes the fleet size of taxi service systems and the effects of the taxi company's information systems...
Infiltrating syringomatous eccrine adenoma of the nipple: a case report

Differential diagnosis for a nodule in the nipple or subareolar area of woman includes both primary neoplasms of breast as well as those from skin and adnexae. A 32-year-old woman presented with a painless 0.5 cm subareolar nodule of her left nipple that she had noticed for several months, with no associated nipple discharge. A biopsy revealed an infiltrating adnexal neoplasm with features similar to those seen in syringomas commonly occurring in locations such as upper face and pubis. The infiltrating syringomatous adenoma of the nipple occurs almost exclusively in women of all ages and is cured by simple excision. Microscopic appearance of such a rare benign infiltrating neoplasm of eccrine duct origin occurring in woman's breast should not be misinterpreted as more common infiltrating primary breast carcinoma. Infiltrating eccrine syringomatous adenoma should be included in the differential diagnosis of a nipple or subareolar nodule occurring in woman.
Unconscious Displacements in College Teacher and Student Relationships: Conceptualizing, Identifying, and Managing Transference

Transference is an unconscious displacement of thoughts, feelings, and behaviors from a previous significant relationship onto a current relationship—a phenomenon that teachers and students both enact with each other, sometimes resulting in a dramatic intensification of those relationships. Transference can pertain importantly to understanding and managing the complex, dynamic, intersubjective system that constitutes the educational helping relationship. Based on an analysis of over 350 items in the college teaching and transference literatures, this article provides: (a) a conceptual foundation for understanding transference, (b) 15 indicators of its possible occurrence, and (c) 9 recommendations for its effective management.
Role of Nonenhanced Multidetector CT Coronary Artery Calcium Testing in Asymptomatic and Symptomatic Individuals

A zero coronary artery calcium score stands alone as perhaps the most powerful negative risk factor for development of a coronary event.
Simulation tools for high intensity rings

Several codes have been developed specifically to simulate beam dynamics in high intensity rings. These codes contain detailed algorithms for modeling the relevant physics in the beam, from single particle transport to important collective effects, including space charge and impedances. Among the various codes, a number of different methods have been adopted for the treatment of space charge. The codes have been applied to a variety of problems in existing machines, as well as for the study, design, and optimization of future machines. A review of existing ring simulation codes is presented, with specific emphasis on the space charge implementation. A more indepth description of the features and application histories of a few specific codes is given, as well as a summary of code benchmarks with experimental data.
Presidential Politics on Tour: George Washington to Woodrow Wilson

This article uses a study of presidential touring to advance an alternative view that nineteenth-century presidents embraced opportunities provided by exogenous forces to develop and maintain a relationship with the public. This argument stands in contrast to traditional accounts that the president was bounded by norms and ideas of proper behavior. Instead, I posit that presidents were much more responsive to evolving opportunities to participate effectively in political competition.
Temperature effects on ion irradiation damage in MgAl2O4 spinel single crystals

The search for radiation resistant materials, particularly ceramics, for the applications in radiation environments has been an active area of research for the past few decades. Among the most well studied ceramics, stoichiometric magnesium aluminate spinel (MgAl{sub 2}O{sub 4}) has been found to be one of the most radiation resistant ceramics. Here, single crystalline samples of (MgAl{sub 2}O{sub 4}), oriented, were irradiated at 100K and 670K with 370--400 keV Xe ions to doses of (1--2){times}10{sup 16} Xe/cm{sup 2}. The microstructures of irradiated samples were subsequently examined by cross-sectional transmission electron microscope. A uniform layer of amorphous phase was observed on the surface of spinel irradiated at 100K. At the end of the damage range underlying the amorphous layer, a disordered transition layer resided on the undamaged substrate. Both high resolution electron microscopy and microdiffraction revealed that the transition layer retained single crystallinity with epitaxial relationship to the underlying substrate. However, the intensity of reflections in the transition layer was significantly weaker than that of the undamaged spinel. No evidence of amorphization was found in the spinel sample irradiated at 670K to a dose of 2{times}10{sup 16} Xe/cm{sup 2}. The reflections exhibit only limited diminution in the heavilymore » damaged region. The observation of reduced intensity of reflections or absent reflections suggests that spinel experiences a structural transition from its original cubic phase (a=0.808 nm) to a new cubic phase (a=0.404 nm). A transition sequence from the original phase to a metastable phase and then to an amorphous phase has been observed. The temperature dependence of metastable and amorphous phase formation has revealed that the accumulation efficiency of cation disorder decreases with increasing irradiation temperature due to the enhancement of interstitial-vacancy recombination.« less
A parallel min-cut algorithm using iteratively reweighted least squares targeting at problems with floating-point edge weights

We formulate and derive a Parallel Iteratively Reweighted least squares Min-Cut solver (PIRMCut).We propose a novel two-level rounding procedure and prove a generalized Cheeger-type inequality.We developed an MPI based parallel implementation of PIRMCut.We demonstrate the parallel scalability of our PIRMCut implementation.We demonstrate PIRMCut significant speed improvement over a serial code. We present a parallel algorithm for the undirected st min-cut problem with floating-point valued edge weights. Our overarching algorithm uses an iteratively reweighted least squares framework. Specifically, this algorithm generates a sequence of Laplacian linear systems, which are solved in parallel. The iterative nature of our algorithm enables us to trade off solution quality for execution time, which is distinguished from those purely combinatorial algorithms that only produce solutions at optimum. We also propose a novel two-level rounding procedure that helps to enhance the quality of the approximate min-cut solution output by our algorithm. Our overall implementation, including the rounding procedure, demonstrates significant speed improvement over a state-of-the-art serial solver, where it could be up to 200 times faster on commodity platforms.
Ethnobotany of the genus Cyphomandra (Solanaceae)

Plants of the genusCyphomandra (Solanaceae) have long been utilized for their edible fruits in their native Latin America. The best-known species is the domesticated tree tomato or tamarillo,Cyphomandra betacea. This species, popular as a raw or cooked fruit, is widely cultivated in Andean South America and is now dispersed worldwide in subtropical areas. Its origin and wild relatives are still unknown, but there are tentative reports of wild populations ofC. betacea in southern Bolivia and northwestern Argentina. Wild species ofCyphomandra such asC. hartwegii, C. sibundoyensis, andC. cajanumensis also produce edible fruits. Other species ofCyphomandra are used in medicinal preparations and as dyes. This group of plants is of increasing economic importance and may have considerable potential for future exploitation.
Flow Induced Vibrations in a Rocket Engine Manifold

Flow induced vibrations are common in engineering. In this paper, turbulent flow in a rocket engine manifold is analyzed using a hybrid RANS-LES turbulence model. Because of the complexity of the geometry considered, a simpler T-junction problem with readily available experimental results 1 was used as a benchmark. Results from both studies are presented in this paper. For the benchmark problem, agreement with experimental data was very good. For the rocket engine manifold we found that vortex shedding and pressure fluctuations within the manifold significantly influence the stability of shear layers and flow through exit cooling tubes. In some cooling tubes near the inflow region, the shear layer blocks the entrance to the tubes, whereas in some other regions flow reversal is observed.
Effect of mycoplasma infection on esterase activity of human FL amnion and WI-38 cells.

SummaryLateral cerebral ventricular administration of sodium salicylate (0.25-1.00 mg) and acetaminophen (0.50-1.00 mg) significantly inhibited production of fever by LP injected iv in the cat. Acetaminophen also caused mild but significant hypothermia in the absence of fever. The ability of these antipyretics to antagonize fever produced by LP, and by agents such as bacterial pyrogens which release LP, is most likely due primarily to a central action to inhibit the effect of LP rather than to a peripheral action to alter LP release from leukocytes or to inhibit entry of LP into the central nervous system.Note added in proof. Since this paper was submitted for publication, evidence for a central antipyretic action of sodium acetylsalicylate against LP-induced fever in the monkey has been reported by Chai, C. Y., Lin, M. T., Chen, H. I., and Wang, S. C., Neuropharmacology 10, 715 (1971).The authors wish to thank Barbara Coldwell for her assistance with some of these experiments.
Research on Environmental Factors in the Immunological Pathogenesis of Type 1 Diabetes

The incidence of type 1 diabetes is increasing year by year,which results from the coaction among heredity,environmental and immunal factors.More and more researches indicate that type 1 diabetes belongs to autoimmune disease,of which the pathogenesis relates to some immunal process such as immune response,immunoregulation and so on.Environmental factors take an important role in the pathogenesis of individuals with hereditary predisposition.Different environmental factors maybe impact on different links of immune response and immunoregulation,including activation of antigens,presentation by antigen presenting cells,production of antibodies,modulation by T cells and so on,which then will result in or aggravate the genesis and development of type 1 diabetes.
405 PLASMA LEVELS OF C-REACTIVE PROTEIN IN OVERWEIGHT CHILDREN AND ADOLESCENTS WITH CARDIAC-RELATED FAMILIAL RISK FACTORS.

Background Obesity has been associated with elevated C-reactive protein and increased cardiovascular risk. Genetic predisposition to atherosclerosis constitutes important risk for developing coronary artery disease (CAD). Objectives To assess the relationship of some cardiac-related familial risk factors (FRF) with the plasma level of highly sensitive C-reactive protein (hs-CRP) in a group of overweight children and adolescents. Methods This study included 101 children and adolescents with body mass index (BMI) ≥ 95th percentile, whose parents answered a questionnaire to address the familial history of diabetes, hypercholesterolemia, hypertension, heart attack, and congenital and/or acquired cardiac diseases. All children participated in a 12-week medically supervised risk factor reduction program. Fasting blood samples were drawn for determination of hs-CRP during the first visit. Results There were 54 males and 47 females, mean age: 11.3 years (range: 5-17), mean BMI Z-score: 2.37 ± 0.32, Hispanic: 50%, Caucasian: 30%, African American: 17%, other races: 3%. There were 36 patients with 1 or none FRF and 65 with 2 or more FRF. Conclusion In this group of overweight children and adolescents the presence of 2 or more familial cardiac-related risk factor was significantly associated with elevated plasma levels of hs-CRP. Elevation of hs-CRP in obese children and adolescents may help identify those individuals at high risk to develop CAD later in life.
Elections, Power, and Local Control: Reining in Chief Prosecutors and Sheriffs

This paper argues that the election of chief prosecutors and sheriffs, and these officials’ narrow focus on crime control and suppression, has contributed to the problem of mass incarceration. The authors propose that the appointment of these positions by officials with broader responsibilities, like mayors, city council members, governors, and state legislators, would help remove barriers that currently prevent needed reforms in the criminal justice system.
Effects of Stereotypes of Salespersons on Consumer Evaluations and Judgements

Subjects read a description of a selling interaction where strong or weak arguments for buying a used car were presented by a used car salesperson or a nonsalesperson. It was proposed that strength of arguments would not affect evaluations of the car and the likelihood that the subject would buy such a car if the arguments were presented by a used car salesperson (heuristic processing would occur) but would affect evaluation of the car and subject’s likelihood of purchase if the arguments were presented by a non-salesperson (systematic processing would occur). The predicted interaction was obtained for ratings of quality and likelihood of purchase. It was predicted that the type of person selling the car would affect recall of the product arguments but this result was not obtained.
The intrinsic, non-supervenient nature of aesthetic properties

Dans le souci d'expliquer la nature des proprietes esthetiques, les philosophes ont utilise differentes distinctions empruntees a la metaphysique et l'epistemologie. L'A. essaie d'elucider cette confusion et demontre comment certaines distinctions metaphysiques et epistemologiques peuvent etre appliquees. Il s'interesse plus particulierement a la distinction intrinseque/extrinseque
Aerogel Cherenkov detector for characterizing the intense flash x-ray source, Cygnus, spectrum.

An aerogel Cherenkov detector is proposed to measure the X-ray energy spectrum from the Cygnus—intense flash X-ray source operated at the Nevada National Security Site. An array of aerogels set at a variety of thresholds between 1 and 3 MeV will be adequate to map out the bremsstrahlung X-ray production of the Cygnus, where the maximum energy of the spectrum is normally around 2.5 MeV. In addition to the Cherenkov radiation from aerogels, one possible competing light-production mechanism is optical transition radiation (OTR), which may be significant in aerogels due to the large number of transitions from SiO2 clusters to vacuum voids. To examine whether OTR is a problem, four aerogel samples were tested using a mono-energetic electron beam (varied in the range of 1–3 MeV) at NSTec Los Alamos Operations. It was demonstrated that aerogels can be used as a Cherenkov medium, where the rate of the light production is about two orders magnitude higher when the electron beam energy is above threshold.
A comparison between two MPC algorithms for demand charge reduction in a real-world microgrid system

This paper describes an evaluation between two model predictive control (MPC) algorithms for microgrid energy management combined with solar production and battery energy storage for demand charge reduction in a real-world microgrid system. The first control algorithm is a constant threshold MPC (CT-MPC) that works well on a system with relatively stable solar generation and a well-known building load profile. CT-MPC can maintain the on-peak demand under a certain value during the entire on-peak rate period. The second control algorithm is an adjusting demand threshold MPC (ADT-MPC). ADT-MPC can better deal with unpredictable solar generation and/or changing building loads. The on-peak threshold under this algorithm is adjusted to the optimal value during the on-peak rate period. As expected, The CT-MPC algorithm performs well when coupled with accurate forecast models while the ADT-MPC algorithm excels when forecasting is more unpredictable.
Alternate bar dynamics in response to increases and decreases of sediment supply

Gravel-bed rivers can accommodate changes in sediment supply by adjusting their bed topography and grain size in both the downstream and cross-stream directions. Under high-supply aggradational conditions, this can result in spatially non-uniform stratigraphic patterns, and the morphodynamic influence of heterogeneous stratigraphy during subsequent degradational periods is poorly understood and has not been studied through physical modelling. A flume experiment was conducted to analyze channel response where alternate bars were developed in a gravel–sand mixture under constant discharge and sediment supply before two supply increases led to the development of heterogeneous stratigraphy beneath alternate bars. The supply was then reduced back to the initial supply rate, causing degradation through that self-formed stratigraphy. Stratigraphic samples were collected and the bed topography and flow depth were measured frequently, which were used with a two-dimensional hydrodynamic model to characterize flow conditions. Migrating alternate bars stabilized during the first equilibrium phase, creating bed surface sorting patterns of coarse bar tops and fine pools. During the first supply increase, the bars remained stable as the pools aggraded. During the second supply increase, the pools aggraded further, causing the boundary shear stress over the bar tops to increase until the bars gained the capacity to migrate and eventually stabilize in new locations. As aggradation occurred, the original sediment sorting patterns were preserved in the subsurface. During the degradational phase, the pools experienced incision and the bars eroded laterally, but this lateral erosion ceased when coarse sediment previously deposited during the bar-building phase became exposed. The results suggest that if a sediment supply increase is capable of filling the pools it can cause stable bars to migrate and the bed to be reworked. These findings also show that heterogeneous stratigraphy can play an important role in determining whether bars persist or disappear after a sediment supply reduction. This article is protected by copyright. All rights reserved.
Changing Pesticide Technology in Meat and Poultry Products

Evolution du programme mis au point dans les annees 1960 aux Etats Unis et visant a developper les methodes analytiques et les appareillages pour la detection des pesticides dans les viandes. Developpement de methodes rapides et modifications technologiques dans le sens d'une prevention de la contamination chimique par les pesticides
Separating heartbeats from multiple people on one bed using geophones: PhD forum abstract

Sensing bed vibrations caused by heartbeats has shown great potentials in detecting and monitoring a person's heartbeats during sleep, without requiring special mattress or sheets, or assuming certain sleeping position/posture. Earlier work has studied how to use this method to detect heartbeats when a single subject is on the bed, and in this study, we aim to separate the heartbeats when multiple subjects share the same bed and the vibration signals are mixed together. Our heartbeat separation algorithm is based upon signal unmixing via time-frequency masking [4], which was originally designed to extract individual voices from two audio mixtures. Though these two problems have similarity, separating heartbeat signals is much harder and poses new challenges, mainly because heartbeat signals have a much smaller frequency range than audio signals, fluctuate considerably from beat to beat, and propagate through a mattress that has much more complex propagation properties than the air.In this study, we address these challenges by carefully designing the signal processing algorithms, especially in phase correction, filtering, window size choice, etc. Through detailed experimentation, we show that our technique can accurately separate two heartbeats (the most common case) using two vibration sensors (geophones in our case) - with an average estimation error below 2 beats per minute.
Targeted box and blocks test: Normative data and comparison to standard tests

Background The Box and Block Test (BBT) is a functional outcome measure that is commonly used across multiple clinical populations due to its benefits of ease and speed of implementation; reliable, objective measurement; and repetition of motion. In this study, we introduce a novel outcome measure called the targeted BBT that allows for the study of initiation, grasping, and transport of objects, and also of object release. These modifications to the existing test may increase the ecological validity of the measure while still retaining the previously stated benefits of the standard BBT. Methods 19 able-bodied subjects performed the targeted BBT and two other standard tests. Using an integrated movement analysis framework based on motion capture and ground force data, quantitative information about how subjects completed these tests were captured. Kinematic parameters at the wrist, elbow, shoulder, thorax, and head, as well as measures of postural control, were calculated and statistically compared across the three tests. Results In general, the targeted BBT required significantly higher RoM at the elbow, shoulder, thorax and head when compared to standard tests. Peak angles at these joints were also higher during performance of the targeted BBT. Peak angles and RoM values for the targeted BBT were close to those found in studies of movements of able-bodied individuals performing activities of daily living. Conclusion The targeted BBT allows analysis of repetitive movements, and may more closely model common real-world object manipulation scenarios in which a user is required to control a movement from pick-up to release.
Light Field Retargeting from Plenoptic Camera to Integral Display

Light fields captured by plenoptic cameras have limited parallax and mismatched resolution causing shallow depth perception when viewed through integral displays. Our lightweight retargeting technique synthesizes light fields of enhanced parallax and controllable depth for immersive displaying experience.
A Stronger Korea-Mongolia Link in a Changing Northeast Asia

South Korea and Mongolia are in similar circumstances, despite differences in size, economic development, and global influence. Having a surprisingly close history and newly-minted democracies, both would benefit from greater space to maneuver among assertive, larger players. Connections are reinforced by cultural and linguistic affinity. Both wish to diversify economic contacts to avoid the “geographic trap” of their locations. Neither by itself is the solution to the other’s problem, but each can help to gain “breathing room.” Complementary interests in relations with Pyongyang also draw them together. Seoul needs to extract the potential of its strong connections, e.g., negotiations about coordinating the NAPCI concept with Mongolia’s Ulaanbaatar Initiative. To the extent that Northeast Asian nations are enmeshed in new, multilateral arrangements, smaller- and mid-sized participants can create some balance to the current tilt toward one or another of their powerful neighbors.
Examining Anosognosia of Neglect

Unilateral neglect (neglect) and anosognosia often co-occur post stroke. It is unknown whether anosognosia of neglect varies for different types of daily activities. The objective is to examine the frequency of anosognosia of neglect for items on the Catherine Bergego Scale (CBS) and to determine the level of agreement between participant/assessor item ratings and total scores. Secondary analysis of data was carried out. We conducted descriptive analyses and interrater reliability analyses (Cohen's kappa) to determine the level of agreement between assessor and participant item ratings. A paired t test was conducted to compare assessor and participant total scores. The frequency of anosognosia among items varied (29.2%-83.3%) and Kappa statistics ranged from -0.07 (no agreement) to 0.23 (fair agreement) for item ratings. There was a significant difference- t(36) = 3.02, p ≤ .01)-between assessor ( M = 8.0, SD = 5.2) and participant-rated ( M = 5.3, SD = 4.5) total CBS scores. Anosognosia is prevalent among those with neglect. Findings highlight the importance of assessing for anosognosia.
Receipt of a pediatric liver offer as the first offer reduces waitlist mortality for adult women.

In liver transplantation, adults with small stature have a greater susceptibility to waitlist mortality. This may explain the persistent waitlist mortality disparity that exists for women. We hypothesized that women who receive early offers of pediatric donor livers have improved waitlist survival, and that preferentially offering these organs to women mitigates this sex-based disparity. We analyzed donor liver offers from 2010 to 2014. Adult candidates who received a first offer that ranked within the first three match run positions from the donors' perspective were classified based on gender and whether they received a pediatric versus adult offer. We used competing risks regression to associate first offer type and waitlist mortality. A total of 8,101 waitlist candidates received a first offer that was ranked within the first three match run positions: 5.6% (293/5,202) men and 6.2% (179/2,899) women received a pediatric donor liver as their first offer. In multivariable analyses, compared with adult-first men, adult-first women (subhazard ratio [sHR] 1.33, 95% confidence interval 1.17-1.51, P < 0.01) had an increased pretransplant mortality risk while pediatric-first men and pediatric-first women had noninferior risks of morality. Pediatric-to-adult and adult-to-adult recipients had similar risks of graft failure and posttransplant mortality. CONCLUSION Our study examines allograft selection by donor age, recipient sex, and in effect size as a means to address disparities in waitlist mortality. We found that women who received a pediatric donor liver as the first offer had a lower risk of waitlist mortality compared with those who receive adult offers. Our data provides a simple approach to mitigating the increased waitlist mortality experienced by women by incorporating donor and recipient size as variables into organ allocation. (Hepatology 2018).
The Return of Antitrust

In the middle of last century, policymakers and the courts came to accept the “Chicago school” interpretation of antitrust: unless it is demonstrated that consumers are being harmed, government should not intervene in firm concentration. Recently, some commentators have charged that this view is mistaken and that government should intervene on the simple grounds that “big is bad” regardless of whether consumers are harmed. This article argues that the reasoning behind this new view is flawed and conflicts with recent decades of antitrust history.
Pharmacologic Agents in Shock

In recent years there has been increasing emphasis and interest in the use of drugs in the treatment of shock. A wide divergence of views exists as to the best method of treating shock, but this is characteristic in clinical medicine of any disease in which the pathophysiology is poorly understood and none of the available forms of therapy is fully satisfactory. It must be emphasized that any drug therapy in shock is secondary to adequate replacement of intravascular volume deficits with colloid and crystalloid solution, correction of hypoxemia with respiratory support, adequate surgical drainage and antibiotics in sepsis, and repair of acid-base and electrolyte abnormalities which exist. Indeed, the combined experience of the Walter Reed shock unit and the surgical research team in Vietnam with several hundred cases of shock has shown that the great majority of these cases represent solely a decreased effective circulating blood volume and respond well to adequate volume administration only.
Understanding Synaptic Mechanisms in SrTiO 3 RRAM Devices

In this paper, we investigated the performance of SrTiO3 (STO) resistive random-access memory (RRAM) as a candidate to realize short-term synaptic elements in neuromorphic circuits. Ionic defect movement within oxides is postulated to play a significant role in resistive state reconfiguration of these devices. This relatively small movement in oxides was sensed by developing a novel measurement technique using differential voltammetry. Using this technique, the widely hypothesized belief of drift and diffusion of ionic defects in oxides was systematically studied and linked to the state reconfiguration in STO RRAM. Next, the devices’ state retention was examined and a consistent decay of the resistive state was observed. The decay rate was found to be a function of the conditioning voltage, allowing us to control the state decay via operational voltages. We then developed a test battery that quantified how these devices operate within a spike-rate encoded learning paradigm. By utilizing a carefully tuned test battery, we were able to quantify the magnitude of potentiation and depression due to varying spike amplitudes and spike rates. These tests provide a systematic methodology to capture the constantly changing resistive state of short-term synaptic elements.
Multiple digitalis receptors A molecular perspective.

The Na,K-ATPase is the only established receptor for cardiac glycosides like digoxin or ouabain. There are now known to be three different isoforms of its principal subunit. These isoforms can differ from one another in their intrinsic affinity for cardiac glycosides. Recent work examines the molecular structure of the binding site. The relative level of expression of the isoforms in cardiac tissue is modified in several developmental, hormonal, and pathological states, contributing to alterations in the digitalis sensitivity of the tissue.
Applications of Light Hydrocarbon Molecular and Isotopic Compositions in Oil and Gas Exploration

Light hydrocarbons (C4-C11) are a significant portion of most crude oils. It is therefore desirable to establish interpretation guidelines from molecular parameters within this boiling range that are diagnostic of source characteristics, thermal maturity, and reservoir alteration processes. This is obviously true for high-maturity or phase-separated liquids that have little or no high-molecular weight biomarkers (see Chapter 9). However, even when C15+ biomarkers are present, evaluation of the light hydrocarbons is considered essential as reservoir rock may be charged by multiple sources. Consequently, the origins and geohistories of the light and heavy hydrocarbons may differ.
International Standards for Neurological Classification of Spinal Cord Injury: Training Effect on Accurate Classification

AbstractObjective: To evaluate the accuracy and agreement of International Standards for Neurological Classification of Spinal Cord Injury (ISCSCI) classification and to determine the effectiveness of formal training for pediatric clinicians.Study Population: Participants (N = 28) in a formal 90-minute classification training session.Outcome Measure: Pre/post-training examination of 1 0 case examples of a variety of neurological classifications.Results: Regardless of years of experience with the ISCSCI, a statistically significant improvement (P < 0.05) in classification was achieved after formal training. Before training, 27%(539 of 1,960) of the questions were answered incorrectly. After training, the percentage of incorrect classifications decreased to 11%(198 of 1 ,960) incorrect (P < 0.05). After training, the percentage of incorrect motor level classifications decreased by 23%(42%to 19%incorrect; P < 0.05). Post-training improvements were also demonstrated (P < 0.05) in classifying sensory levels (9...
Prognostic value of PET-CT in early stage Hodgkin Lymphoma (HL) using updated 5 point scoring system.

e19013Background: The Lymphoma response criteria (2007), updated in 2014, use PET-CT to evaluate response in early stage HL (Cheson et al). PET-CT is accurate in predicting responses, however there...