cssi/SciSciGPT-SciSciNet huggingface dataset:
Spontaneous malignant lymphoma in a new-world primate.

A spontaneous hematopoietic neoplasm in a cotton-top marmoset (Saguinus oedipus) was characterized by perivascular infiltration and invasion of the liver, kidneys, adrenals, spleen, lymph nodes, bone marrow, and lungs by a pleomorphic primitive reticular cell. A significant fraction of the circulating white cells was of the same cell type. The disease was diagnosed as lymphosarcoma of the reticulum-cell type with features similar to viral-induced malignancy previously described. There are few reports of spontaneous hematopoietic neoplasms in nonhuman primates. According to a recent survey, only 21 cases have been reported (1). The marmoset is a small new-world primate that has been investigated extensively as a possible animal model for the study of several important human diseases (2, 3), including cancer (4, 5). Recently HUNTet al. (6) induced a disease closely resembling malignant lymphoma in the marmoset (Saguinus oedipus) and the owl monkey (Aotus trivirgatus) by the adminis­ tration of Herpesvirus saimiri. The spontaneous occurrence in a cotton-top marmoset (Saguinus oedipus) of a disease with many features consistent with malignant lymphoma and with most of the manifestations of the disease that was induced by HUNTet at. (6) is discussed.
A study of the relationship of storytelling ability and reading comprehension in fourth and sixth grade African-American children

The purpose of the present investigation was to examine the relation of storytelling skills to achievement in reading comprehension in African-American children. Socioeconomic status (SES), gender and developmental level of children's stories were examined as predictors of reading achievement. A total of 80 children in the fourth and sixth grades served as subjects. Results indicated that correlations of the narrative variables with reading achievement were significant for story level (0.37) and clauses per T-unit (0.33). These results are discussed relative to the effect of oral language on academic achievement and the importance of examining this relationship in culturally and linguistically diverse groups.La recherche presentee ici a eu pour but d'examiner le rapport entre les capacites de conter des histoires et le niveau atteint en comprehension a la lecture chez des enfants afroamericains. Le statut socioeconomique, le sexe et le niveau de developpement des histoires des enfants ont ete examines en ...
Alteration of lens electrolyte transport parameters following transient oxidative perturbation.

Rabbit lenses were incubated, in vitro, for 20 hr. During the first 60 min of the incubation period, the lenses were exposed to hydrogen peroxide at specified concentrations. Deranged electrolyte balance was observed in lenses exposed to hydrogen peroxide concentrations exceeding 0.1 mM.Lenticular sodium pump activity, as evidenced by lens 86Rb uptake, was reduced to 61% of control when examined immediately after exposure to 0.5 mM hydrogen peroxide for 1 hr. Upon further incubation in peroxide-free medium, the sodium pump activity of hydrogen peroxide treated lenses continued to deteriorate. The deterioration of sodium pump activity in lenses transiently challenged with hydrogen peroxide was not altered by supplementation of the incubation medium with antioxidants or by substitution of calcium in the medium.Lenticular potassium permeability, as evidenced by the rate of 86Rb efflux from the lens, was found to be elevated immediately after exposure to 0.5 mM hydrogen peroxide for 1 hr. However, no further ...
Speciation history of the North American funnel web spiders, Agelenopsis (Araneae: Agelenidae): phylogenetic inferences at the population-species interface

Intra- and interspecific relationships of 12 out of 13 described species as well as a potential new species in the spider genus Agelenopsis (Araneae: Agelenidae) were analyzed using sequence data from two mitochondrial genes, cytochrome oxidase I (COI) and 16S ribosomal RNA. Approximately half of the species examined formed well-supported monophyletic groups, whereas the rest of the species were part of well-supported monophyletic species groups. Rather than viewing cases where species were not identified as being monophyletic as poor taxonomy, these cases more likely represent recent speciation and offer insights into the process of speciation. The clade with the lowest levels of interspecific sequence divergence was found in eastern North America, whereas western species displayed much higher levels of interspecific divergence. These patterns appear to extend below the species level as well, with southwestern species exhibiting the highest levels of intraspecific sequence divergence and geographic structuring. The relationship between Agelenopsis and Barronopsis, a genus once considered a sub-genus of Agelenopsis, was also examined. The two genera are reciprocally monophyletic but more generic level sampling is needed to confirm an apparent sister relationship between the two.
Regional Trends in Nimbus-7 OLR: Effects of a Spectrally Nonuniform Albedo*

Abstract Data from the Earth Radiation Budget wide-field-of-view sensors on board the Nimbus-7 satellite during the period 1979–87 indicate a statistically significant downward trend in daytime outgoing longwave radiation (OLR) of up to 14 W m−2 decade−1 over the Sahara desert region of Africa. Reflected solar radiation shows a positive trend of the same magnitude. No significant trends in temperature or cloudiness over the region can be demonstrated. Atmospheric desert dust aerosols increase over the same period, but the spatial pattern of the dust trend is different from that of the OLR and reflected solar trends. A plausible explanation is that these trends are instrumental in nature and are caused by degradation of the Suprasil filter dome that covers the reflected solar channels. The filter dome degradation is greater for shorter wavelengths of the solar spectrum compared to red and near-infrared wavelengths. This enhanced degradation at shorter wavelengths, combined with the increased albedo of dese...
Towards Efficient And Comprehensive Healthcare/Medical Monitoring System: Nano-Scale Body-Centric Networks (Nano-Health)

A gradual shift from GHz to THz range in the past few years has celebrated the invention of many new technologies in the field of communications, computers, electronics and medicine. Nano-networks are the new era technologies defined as electronic components and their interconnection within a single chip on a nano-scale [1]. The concept of Network on Chip (NoC) is exploited on a scale ranging from micrometers to nanometers. This term is also referred to as the network-like interconnection of nano-materials such as carbon nanotubes arrays [2,3]. The research done in the past has broadly explained the same concept of nano-networking with different terminologies and slightly varying definitions depending on the mechanisms of networking and communication. In this study, the main focus is on propagation investigation at THz frequencies in human tissues, such as blood, fat, and skin, which is conducted with the aim to fix the early paradigms for a pioneering investigation in this field. The path loss values obtained from numerical simulation have been compared to an analytical model in order to verify the feasibility of the numerical analysis which can be subsequently extended in order to take into account more realistic parameters such as the antenna, or inhomogeneity of the materials. The study also explores the methods and techniques to characterize biological medium necessary for Nano-network communication. Time Domain Spectroscopy has immensely contributed in the field of medical imaging, analysis of protein and other biomolecules, finger print analysis of chemicals and food quality control [4]. The aim is to utilise this technique to study the dielectric properties of various biological samples. Subsequent sections of the chapter will discuss various biological entities such as skin & its layers, blood, hydration shell and sweat ducts. As one begins to understand the human body anatomy from wireless communication perspective, one can realizes its overall complexity and random nature. The main objective of this work is the potentiality of nano-scale EM communication exploiting the THz regime of the electromagnetic spectrum. The nano-scale EM communication becomes an obvious choice due to the fact that molecular information for a human body is indeed sensitive in the THz regime. Additionally, this part of the spectrum is much safer to interact at a cellular scale that its counterparts in the microwave or gigahertz range. The proposed in-vivo body nano-networks ensures their stability without disturbing the harmony of in-built molecular structure of the body. Moreover, in most of the cases medicine fails to understand the root cause of the problem but once a monitoring network is established, one can extract various unknowns and treat them effectively.
Drosophila Males Produce a Pheromone which Inhibits Courtship

Normal Drosophila males produce a volatile pheromone which inhibits courtship. This chemical cue is not identical to the pheromone made by mated female flies, which also inhibits male sexual behavior. Mutant olfC males, which fail to respond to several organic compounds, are not inhibited by the pheromone made by males; hence, unlike normal sexually mature males, olfC males court each other vigorously.
Laparoscopic Liver Surgery for the Management of Hepatocellular Carcinoma: The American Perspective

Despite better understanding and advances in oncology, the best available therapeutic option for the management of hepatocellular carcinoma (HCC) is surgical – either liver transplantation or resection. Liver transplantation appears most attractive since it treats the primary tumor and the field defect associated with the underlying liver disease. However, this option is feasible only when there are an adequate number of organs available and when the disease and patient meet certain stringent criteria. Most centers abide by the Milan criteria [1] to determine candidacy for liver transplantation. These are a single tumor ≦5 cm, two or three tumors all <3 cm, absence of major vascular invasion, and no extrahepatic disease. Unfortunately, only a minority of hepatoma patients fit these morphological parameters. Many other cirrhotic patients do not fulfill the requirements for transplantation due to comorbidity or psychosocial reasons.
The Value-Relevance Of The Cumulative Effect Reporting Method: Some Evidence In Support Of FAS 154

The Financial Accounting Standards Board (FASB) issued Statement of Financial Accounting Standards No. 154 (FAS 154), Accounting Changes and Error Corrections replacement of APB Opinion No. 20 and FASB Statement No. 3 (FASB 2005). The retrospective application reporting method of FAS 154 is a significant departure from the cumulative effect method of its predecessor standard, Accounting Principles Board Opinion No. 20 (APB No. 20) (AICPA 1971). This study examines the value relevance of the cumulative effect reporting method used a priori FAS 154. The results indicate that for most years the cumulative effect was not a significant variable in explaining the market value of a firm and there was inconsistency in the sign and size of the coefficient. Accordingly, these results suggest that FAS 154, aside from its other merits, eliminated from financial statements accounting information that was not relevant, thus providing support for the issuance of FAS 154.
Norm Perception as a Vehicle for Social Change

How can we change social norms, the standards describing typical or desirable behavior? Because individuals’ perceptions of norms guide their personal behavior, influencing these perceptions is one way to create social change. And yet individuals do not form perceptions of typical or desirable behavior in an unbiased manner. Individuals attend to select sources of normative information, and their resulting perceptions rarely match actual rates of behavior in their environment. Thus, changing social norms requires an understanding of how individuals perceive norms in the first place. We describe three sources of information that people use to understand norms—individual behavior, summary information about a group, and institutional signals. Social change interventions have used each source to influence perceived norms and behaviors, including recycling, intimate-partner violence, and peer harassment. We discuss conditions under which influence over perceived norms is likely to be stronger, based on the source of the normative information and individuals’ relationship to the source. Finally, we point to future research and suggest when it is most appropriate to use a norm change strategy in the interest of behavior and social change.
Relationship of chromocenter number, size, and density to plant biomass

SUMMARYA variety of plant species and cultivars were stained for chromocenters using the barium hydroxide, sodium saline citrate (SSC), Giemsa procedure (DNA denaturation, incubation-renaturation, staining), in order to test the hypothesis that larger (biomass) species have larger, more numerous, and more intensely-staining chromocenters. In all species and cultivars examined, results confirmed the hypothesis. Since chromocenters are believed to be composed primarily of heterochromatin/repetitive DNA (which has been postulated to shorten the cell cycle), it is likely that chromocenters modulate species size/biomass. Among closely related species, larger/more biomassive cultivars contained larger, more numerous, and more intensely-staining chromocenters than smaller/less biomassive cultivars.
Follow-up with primary care providers for elevated glycated haemoglobin identified at the dental visit

Objectives This study examined patient experiences after receiving elevated diabetes screening values using blood collected at a dental clinic. It explores patients' reactions to screening, whether or not they sought recommended medical follow-up, and facilitating factors and barriers to obtaining follow-up care. Methods At the comprehensive care clinics at a large, urban College of Dentistry in the United States, haemoglobin A1C (HbA1C) values were obtained from 379 study participants who had not been previously diagnosed with diabetes. In all, 169 (44.6%) had elevated HbA1C values. We analysed quantitative and qualitative data concerning these patients' follow-up with primary care providers (PCPs). Results We were able to contact 112 (66.3%) of the 169 study participants who had an elevated HbA1C reading. Of that group, 61 (54.5%) received recommended follow-up care from a PCP within 3 months, and an additional 28 (25.0%) said they intended to seek such care. Qualitative themes included the following: the screening letter – opportunity or burden, appreciation for the 3-month follow-up call and barriers to medical follow-up that included the following: lack of knowledge about diabetes, not understanding the importance of follow-up, busyness, financial concerns, fear and denial. Conclusions Quantitative and qualitative data demonstrate that dentists, dental hygienists and nurses are well poised to discover and translate new models of patient-centred, comprehensive care to patients with oral and systemic illness.
Thermal Method to Reduce the Polysilicon Resistance for Deep Submicron Integration Process

In this paper, a new annealing process to reduce polysilicon resistance without implant dosage adjustment has been proposed. With increasing the annealing temperatures, polysilicon grain size increases and causes the polysilicon resistance reduction. After annealing in inert gas ambient at 950◦C for 5 min, the polysilicon resistance can be obviously reduced more than 7.7%, comparing to the 800◦C for 5 min annealing process. And the threshold voltage and saturation current characteristics of submicron MOS device can be maintained almost same as before, due to the minor doping profile variations. Therefore, this new annealing process without device performance variations can be a candidate to reduce the polysilicon resistance applied to deep submicron integration circuit process. © The Author(s) 2016. Published by ECS. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives 4.0 License (CC BY-NC-ND, http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reuse, distribution, and reproduction in any medium, provided the original work is not changed in any way and is properly cited. For permission for commercial reuse, please email: oa@electrochem.org. [DOI: 10.1149/2.0171609jss] All rights reserved.
What Have We Done for You Lately? The Role of the American Society for Microbiology in Advancing Clinical Microbiology

The American Society for Microbiology (ASM) is distinguished as the oldest and largest life sciences organization with a membership worldwide of 47,000. With an organization that represents the size and scope of the disciple of microbiology, its members can begin to consider the value of their membership. This article outlines the breadth and scope of activities that ASM has and is working on to advance clinical microbiology.
Thermal oxidation aging of polydicyclopentadiene and composites

The thermal aging and oxidation behavior of polydicyclopentadiene and composites was investigated, and the effects on thermal and mechanical properties were determined. Thermal and mechanical properties were measured by dynamic mechanical analysis, static tensile test, and short-beam shear tests. Diffusion limited oxidation was observed and oxidation was limited within the surface region (∼100 µm) of the sample. Single-fiber push-out test methodology was developed to directly measure the bond strength of fiber-matrix interface, and results showed that aging of composites at 150°C caused significant degradation of the fiber-matrix interface, while aging at 100°C for up to half a year had little effect on interface properties. The fiber-matrix interface strength near exposed surfaces decreased more quickly during aging compared to nonoxidized regions far beneath surfaces. POLYM. COMPOS., 2016. © 2016 Society of Plastics Engineers
Watson for Genomics: Moving Personalized Medicine Forward

The confluence of genomic technologies and cognitive computing has brought us to the doorstep of widespread usage of personalized medicine. Cognitive systems, such as Watson for Genomics (WG), integrate massive amounts of new omic data with the current body of knowledge to assist physicians in analyzing and acting on patient's genomic profiles.
‘Not Beautiful in the Right Way’: Star Image, Politics and Romance in The Way We Were (1973)

In the early 1970s, the controversial anti-communist Hollywood witch-hunts of the 1940s and 1950s finally received their first overt treatment in the popular romantic melodrama The Way We Were (Pollack, 1973). Starring Barbra Streisand (Katie Morosky) and Robert Redford (Hubbel Gardiner), the film is about an unlikely romance between a fiery Jewish radical and a handsome and privileged Wasp, and the conflict between careers, personal relationships and political principles in blacklist era Hollywood. By downplaying the political story, however, it was not the frank, revealing and long overdue story of political paranoia and destroyed careers that many critics had hoped for. The film was a major hit, nonetheless, owing to two major factors. One factor was the presence of two of America’s most popular movie stars and their compelling on-screen chemistry. The other was the film’s shrewd accommodation of contemporary concerns, namely, the social wars of the 1960s and the explosion in identity politics in the 1970s. These concerns were expressed in the film’s story, themes and, crucially, through the conflicting cultural meanings of Streisand’s and Redford’s star personae.
Allylic functionalization of unactivated hydrocarbons

W have been exploring the selective functionalization of unactivated hydrocarbons. We have developed a catalytic enantioselective allylic amination of unactivated olefins via a [2,3]-rearrangement (Scheme 1). In this method, a diimido-sulfur reagent serves as the source of nitrogen, and it reacts selectively with terminal olefins through a hetero-ene reaction. The resulting zwitterionic ene adduct undergoes a Pd-catalyzed enantioselective [2,3]-rearrangement to generate chiral amines in high enantiomeric excess. Our approach is conceptually distinct from other enantioselective allylic amination strategies. The synthetic utility of our process is being explored by converting simple and inexpensive terminal olefins into functional materials, such as the pharmaceutical drugs Vigabatrin and Januvia. Based on this chemistry, we have also developed a copper-catalyzed allylic alkylation of unactivated olefins and dienes (Schemes 2 and 3). This represents a general method for functionalizing unactivated hydrocarbons with aromatic, aliphatic, and vinyl Grignard reagents. Our recent discoveries represent a conceptual framework for the generalized functionalization of unactivated olefins. Scheme 1. Allylic Amination of Unactivated Olefins
Effect of Progressive Calisthenic Push-up Training on Muscle Strength and Thickness.

Kotarsky, CJ, Christensen, BK, Miller, JS, and Hackney, KJ. Effect of progressive calisthenic push-up training on muscle strength and thickness. J Strength Cond Res 32(3): 651-659, 2018-Calisthenics, a form of resistance training, continue to increase in popularity; however, few studies have examined their effectiveness for muscle strength improvement. The purpose of this study was to determine whether progressive calisthenic push-up training (PUSH) is comparable with traditional bench press training (BENCH) as a technique for increasing muscle strength and thickness. Twenty-three healthy, moderately trained men (mean ± SD: age 23 ± 6.8 years) completed the study. Subjects were randomly assigned to PUSH (n = 14) and BENCH (n = 9) groups and were trained 3 days per week for 4 weeks. Muscle thickness (MT), seated medicine ball put (MBP), 1 repetition maximum (1RM) bench press, and push-up progression (PUP) were measured before and after training. Results revealed significant increases in 1RM (p 0.05). This study is the first to demonstrate that calisthenics, using different progressive variations to maintain strength training programming variables, can improve upper-body muscle strength.
Advances in Retinal Prosthetic Research: A Systematic Review of Engineering and Clinical Characteristics of Current Prosthetic Initiatives

ABSTRACTPurpose: To date, reviews of retinal prostheses have focused primarily on devices undergoing human trials in the Western Hemisphere and fail to capture significant advances in materials and engineering research in countries such as Japan and Korea, as well as projects in early stages of development. To address these gaps, this systematic review examines worldwide advances in retinal prosthetic research, evaluates engineering characteristics and clinical progress of contemporary device initiatives, and identifies potential directions for future research in the field of retinal prosthetics.Methods: A literature search using PubMed, Google Scholar, and IEEExplore was conducted following the PRISMA Guidelines for Systematic Review. Inclusion criteria were peer-reviewed papers demonstrating progress in human or animal trials and papers discussing the prosthetic engineering design. For each initiative, a description of the device, its engineering considerations, and recent clinical results were provided...
Open beauty production and modifications in PbPb collisions at 5.02 TeV with CMS

Abstract Beauty production and modifications in heavy-ion collisions are considered to be one of the key measurements to address the flavour-dependence of in-medium energy loss in PbPb collisions at the LHC. The CMS experiment has excellent capabilities for measuring b-quark production thanks to the excellent performances of its muon and tracker system, allowing the measurement J / ψ mesons from B meson decays, separately from prompt production, as well as fully reconstructed B mesons. In this talk, CMS will present the first measurement of the v 2 Fourier harmonic and the R AA down to p T > 3 GeV/c , for J / ψ produced in B meson decays, in PbPb collisions at s N N = 2.76 TeV , as a function of transverse momentum, rapidity and event centrality. In addition, the measurement of R AA for fully reconstructed B mesons will be shown, for the first time, in PbPb collisions at 5.02 TeV.
Cystoscopy: A useful investigation tool to diagnose urinary schistosomiasis in Ireland, a non-endemic country

Abstract Urinary schistosomiasis is caused by the parasite Schistosoma haematobium and is endemic in the African and Asian countries, usually in areas with no proper sanitation. We present a case of a 12 year old boy seen in Ireland where these parasites are not endemic. An uncommon modality was used to confirm the condition and after being treated with Praziquantel the child made an excellent recovery.
A note on almost difference sets in nonabelian groups

We present a new construction of almost difference sets. The construction occurs in nonabelian groups of order 4N with a subgroup H of order N so that H has an (N,\(\frac{N-1}{2}\),\(\frac{N-3}{4}\)) difference set (and hence N must be an integer that is 3 (mod 4)).
Linking Complex Alterations in Functional Network Connectivity to Disorders of Consciousness

In the last decade, research has focused on finding neural correlates of consciousness for diagnosis and prognosis after severe brain injury using neuroimaging studies. Because patients with disorders of consciousness are not or only limitedly capable of following instructions, studies investigating resting-state connectivity have been a focus of interest. This chapter gives an overview of the research on functional network connectivity in disorders of consciousness and common methods used to investigate these alterations such as independent component analysis, seed-based approaches, graph theory, and spectral dynamic causal modeling. Research demonstrates that properties of resting-state networks may provide further evidence for diagnosis and prognosis but also show limitations in interpretability. In addition, the existence of so-called hot zones of neuronal correlates of consciousness is discussed. In the second half of this chapter, we outline the caveats of resting-state functional imaging in severe brain injury. Motion, artifacts, normalization procedures, and interpretability pose serious obstacles when analyzing resting-state connectivity particularly in the injured brain. Nevertheless, resting-state connectivity analyses are a powerful tool to investigate patients with disorders of consciousness.
Techniques to Minimize Blood Loss During Hepatectomy

The liver has such a rich blood supply and significant bleeding risk that it was thought by many including Galen, one of the most famous ancient Greek physicians, to be the source of venous blood. In the 1970s, observed operative mortality rates from hepatectomy procedures ranged from 17% to 24%. Comparatively, modern series show rates of mortality after hepatectomy of around 5% or significantly less. Risk factors associated with operative mortality after partial hepatectomy include operative blood loss and transfusion requirement. Bleeding and blood transfusions may even increase the risk of recurrence after hepatectomy for malignant diseases. Thus, reducing operative blood loss is of paramount importance. Many techniques exist for attempting to reduce operative blood loss during partial hepatectomy; however, the best techniques to reduce blood loss have been difficult to determine and great controversy persists. This chapter will focus on the current techniques to reduce blood loss during hepatectomy and provide recommendations.
Commissioning an in-room mobile CT for adaptive proton therapy with a compact proton system

Purpose To describe the commissioning of AIRO mobile CT system (AIRO) for adaptive proton therapy on a compact double scattering proton therapy system. Methods A Gammex phantom was scanned with varying plug patterns, table heights, and mAs on a CT simulator (CT Sim) and on the AIRO. AIRO-specific CT-stopping power ratio (SPR) curves were created with a commonly used stoichiometric method using the Gammex phantom. A RANDO anthropomorphic thorax, pelvis, and head phantom, and a CIRS thorax and head phantom were scanned on the CT Sim and AIRO. Clinically realistic treatment plans and nonclinical plans were generated on the CT Sim images and subsequently copied onto the AIRO CT scans for dose recalculation and comparison for various AIRO SPR curves. Gamma analysis was used to evaluate dosimetric deviation between both plans. Results AIRO CT values skewed toward solid water when plugs were scanned surrounded by other plugs in phantom. Low-density materials demonstrated largest differences. Dose calculated on AIRO CT scans with stoichiometric-based SPR curves produced over-ranged proton beams when large volumes of low-density material were in the path of the beam. To create equivalent dose distributions on both data sets, the AIRO SPR curve's low-density data points were iteratively adjusted to yield better proton beam range agreement based on isodose lines. Comparison of the stoichiometric-based AIRO SPR curve and the "dose-adjusted" SPR curve showed slight improvement on gamma analysis between the treatment plan and the AIRO plan for single-field plans at the 1%, 1 mm level, but did not affect clinical plans indicating that HU number differences between the CT Sim and AIRO did not affect dose calculations for robust clinical beam arrangements. Conclusion Based on this study, we believe the AIRO can be used offline for adaptive proton therapy on a compact double scattering proton therapy system.
Women, Gender Equality, and Digital Technology

This exploratory study investigates the subject of the gender equality and women’s empowerment and their engagement in smart development, with a primary focus on ICT and wearable technologies, such as small-scale intelligent devices and interactive sensor elements. Although a growing body of academic research on the topic is increasing, there is a gap in envisioning how aspects of the wearable technologies can optimally engage with the context of the development field and women’s empowerment in developing countries. The main contributions of this study combine both empirical and conceptual design components to support the design and evaluation of a smart development that enhances gender equality and women’s empowerment in developing countries. The first step towards this study was to con-duct a pilot study that involved five newly arrived African women in the USA. Participants were asked to discuss their experience with the role that current digital technology plays in women’s empowerment and gender equality.
Surrogate endpoints in the management of acute myeloid leukemia

4872 Acute Myeloid Leukemia (AML) is a heterogeneous disease. Only 55-75% of patients will achieve complete remission (CR) after chemotherapy and a high percentage of CR patients relapse after a short term. Surrogate endpoints for monitoring patient’s response to therapy, as well as early onset of disease relapse are of critical importance for the management of AML. In this study, proteomic changes of AML patients prior and after chemo-therapy were compared using ProteinChip arrays and time-of -flight mass spectrometry (SELDI). A total of 92 serum samples of 54 AML patients were analyzed in this study, among them 37 were collected at time of diagnosis, 35 at different stages of disease during follow up and 20 at long term CR (at least 2 years). Comparison of protein profiles of sera samples at diagnosis and at CR revealed 3 differentially expressed protein peaks which level correlates with the disease status. Level of AML-1 is elevated whereas levels of AML-2 and AML-3 are decreased at time of diagnosis, and regain normal expression at CR. The area under the ROC curve for AML 1-3 as surrogate markers for monitoring the effectiveness of therapy is 0.88, 0.88 and 0.81, respectively. Changes in peak intensity of these markers are also indicative of changes of the disease status within the same patient when multiple follow up samples were available. Protein identity of AML-2 has been determined and confirmed by western blot analysis. Protein identification of AML-1 and 3 are currently being performed.
Corrigenda : "stabilization in H∞R(D)"

In this corrigenda we outline the necessary changes to the paper [3] so that the main result in that paper is made correct. The mistake the author made in the previous version was that the condition that f1 being positive on the zeros of f2 was not strong enough ∞ to guarantee the existence of the logarithm in HR (D).
Carotid Endarterectomy Technique

Cerebral ischemia is a disease of immense impact on patients worldwide. Indeed, in the next decade, it is predicted to become the number one cause of death and disability in the developing world. It remains a major disabler in North America, especially in robbing patients of independence and productivity. The needs for prevention, both medical and surgical, are great. One of the methods which traditionally addresses this is carotid endarterectomy (CEA) which in selected patients decreases the risk of future stroke from atherosclerotic artery-to-artery emboli or occlusion. Along with other medical and surgical risk factor prevention strategies, carotid endarterectomy is one of the important potential surgical methods to address atherosclerotic ischemic risk and improve patient outcome.
Failure to Diagnose and Treat Hyperparathyroidism Among Patients with Hypercalcemia: Opportunities for Intervention at the Patient and Physician Level to Increase Surgical Referral.

Background Hyperparathyroidism is both underdiagnosed and undertreated, but the reasons for these deficiencies have not been described. The purpose of this study was to identify reasons for underdiagnosis and undertreatment of hyperparathyroidism that could be addressed by targeted interventions. Materials and methods We identified 3,200 patients with hypercalcemia (serum calcium >10.5 mg/dL) who had parathyroid hormone (PTH) levels evaluated at our institution from 2011 to 2016. We randomly sampled 60 patients and divided them into three groups based on their PTH levels. Two independent reviewers examined clinical notes and diagnostic data to identify reasons for delayed diagnosis or referral for treatment. Results The mean age of the patients was 61 ± 16.5 years, 68% were women, and 55% were white. Fifty percent of patients had ≥1 elevated calcium that was missed by their primary care provider. Hypercalcemia was frequently attributed to causes other than hyperparathyroidism, including diuretics (12%), calcium supplements (12%), dehydration (5%), and renal dysfunction (3%). Even when calcium and PTH were both elevated, the diagnosis was missed or delayed in 40% of patients. For 7% of patients, a nonsurgeon stated that surgery offered no benefit; 22% of patients were offered medical treatment or observation, and 8% opted not to see a surgeon. Only 20% of patients were referred for surgical evaluation, and they waited a median of 16 months before seeing a surgeon. Conclusion To address common causes for delayed diagnosis and treatment of hyperparathyroidism, we must improve systems for recognizing hypercalcemia and better educate patients and providers about the consequences of untreated disease. Implications for practice This study identified reasons why patients experience delays in workup, diagnosis, and treatment of primary hyperparathyroidism. These data provide valuable information for developing interventions that increase rates of diagnosis and referral.
Active interrogation of Special Nuclear Material containers using AmBe quasi-forward biased directional source and PGNAA.

Abstract Special Nuclear Material (SNM) including 95% 235U and 239Pu is capable of being identified by utilizing a quasi-forward directional AmBe source from Patent No: US20190013109A1 using Prompt Gamma Neutron Activation Analysis (PGNAA) simulated with Monte-Carlo N-Particle transport 6.2 (MCNP). HPGe and LaBr3 detector arrays were used to identify and quantify the peak-to-background and peak-to-total ratios of the associated photon spectra from the SNM encased in a polyethylene shield. The conducted simulations varied the volume of the SNM and neutron source strength in the MCNP data card to conduct an uncertainty analysis. Photopeaks identified include K-shell X-rays from 235U and 239Pu, 61 keV from fission, 2.223 MeV prompt gamma from hydrogen, 511 keV annihilation, and a single and double escape peak from the prompt gamma interaction from hydrogen. Relationships between peak-to-total and peak-to-background as a function of SNM and particle history were investigated to aid in the analysis. The capabilities of both detector systems to acquire well resolved photopeak with a 5% relative error or less, with a 1 Ci source activity, and a peak-to-background ratio of 1.15. This was determined to take 326 s for LaBr3 and 163 s for HPGe which is comparable to current methods for material detection which take between 100 and 900 s to acquire.
Effects of the Atmospheric Compensation Method on Hyperspectral Rare Target Detection

This study examines how hyperspectral rare target detection performance is affected by the method of atmospheric compensation used to convert the data to reflectance units. Rare and subpixel target detection algorithms employ contrast enhancement methods to suppress signatures from the background materials. Therefore, when evaluating atmospheric compensation methods, it is important to consider their accuracy in contrast-enhanced space. In particular, a key requirement for good detection is the suppression of atmospheric band residuals in the reflectance spectra, making them as smooth as possible. This explains the success of the empirical Quick Atmospheric Correction (QUAC) algorithm and the importance of supplementing first principles methods with spectral polishing. We illustrate these findings using two data sets acquired by the Rochester Institute of Technology (RIT), three different whitening-based detection algorithms, and three different atmospheric compensation algorithms, QUAC, FLAASH and ATCOR.
Physical, Microbial, and Chemical Quality of Hot-Air-Dried Persimmon (Diospyros kaki) Chips during Storage

Recent efforts have been made to develop hot-air-dried chips as a value-added product for persimmon fruit (Diospyros kaki). However, the long-term quality of this product and its dependence on processing conditions and packaging type have not yet been explored. Hence, in this work, chips were prepared from “Hachiya” persimmon fruit in 2 ways: 2 mm thickness fruit slices, hot-air-dried for 5 hours (Preparation 2–5), and 6 mm slices, dried for 10 hours (Preparation 6–10). The dried chips were then packaged into 2 bag types (plastic zip-top and metallized polyethylene terephthalate (Met-PET) with desiccant packets), stored under ambient conditions, and sampled for moisture-related, microbial, texture, and chemical quality traits throughout the 1-year storage study. It was found that–with the exception of a marked decrease in ascorbic acid (vitamin C)—all 4 Preparation/Packaging combinations yielded products that maintained acceptable color, microbial, nutritional, and textural quality throughout the entire study. Compared to Preparation 2–5 chips, Preparation 6–10 chips generally had lower contents of healthy nutrients—antioxidant compounds, ascorbic acid, and carotenoids. Evidence of invertase activity was found for Preparation 6–10 chips but not for Preparation 2–5 chips. For both preparations, the contents of ascorbic acid and carotenoids experienced time-dependent decreases. Plastic zip-top bags and Met-PET bags with desiccant packets performed equally well as packaging for most of the quality metrics tracked during this study. Overall, this work has demonstrated that hot-air-drying of persimmon slices is a promising approach to create a value-added product with at least one year of shelf-life.
Projecting spatiotemporally explicit effects of climate change on stream temperature: A model comparison and implications for coldwater fishes

Abstract Conservation planners and resource managers seek information about how the availability and locations of cold-water habitats will change in the future and how these predictions vary among models. We used a physical process-based model to demonstrate the implications of climate change for streamflow and water temperature in two watersheds with distinctive flow regimes: the Snoqualmie watershed (WA) and Siletz watershed (OR), USA. Our model incorporated a downscaled ensemble of global climate model outputs and was calibrated with in situ and remotely sensed water temperatures. We compared predictions from our processed-based model to those from a publicly available and widely used statistical model. The process-based model projected greater changes in summer maximum water temperatures for the mixed-rain-snow Snoqualmie watershed than for the rain-dominated Siletz watershed as a result of the near-complete loss of winter snowpack and significant reduction in summer flow in the Snoqualmie watershed expected by the 2080s. Both models projected generally similar future spatial patterns of maximum water temperature in the two rivers, with cool reaches distributed farther upstream and fewer in number. However, the process-based model projected higher spatial heterogeneity in water temperature due to our spatially explicit simulation of streamflow and because we calibrated the model with spatially continuous remotely sensed water temperature data. We used stream temperature projections to assess the vulnerability of Pacific salmon and trout to changes in the spatial distribution of cold-water habitats during August by the 2080 s. Results suggest that salmonids may have fewer summertime cold-water habitats in both watersheds. Projected stream warming may further limit particular species and life stages, especially in the Snoqualmie watershed. Our comparison of models highlights the importance of considering what might be gained by using a process-based model for evaluating and prioritizing management actions that mitigate climate impacts on cold-water habitats for stream fishes.
Aging Detection of Multiple Power Switches in a Live 3-Phase Inverter using Reflectometry

Reflectometry-based degradation detection technique designed around spread spectrum time domain reflectometry (SSTDR) for multiple power semiconductor devices in a live 3-phase inverter has been proposed in this paper. Using SSTDR, aging-related impedance variation within the power semiconductor device can be identified without interrupting the circuit's normal operation. The rapid change in the SSTDR propagation path due to the high switching frequency of power switches makes real-time health monitoring challenging. Existing SSTDR based techniques proposed for degradation detection of the DC-DC converter and single-phase grid-tied H-bridge PV inverter require a large number of SSTDR test data acquisition to minimize the error caused by rapid change in the SSTDR propagation path. Moreover, a three-phase inverter may utilize a very complicated switching scheme and multiple impedance paths compared to the other converter topologies used in the previous SSTDR-based degradation detection technique. The proposed method requires significantly less amount of SSTDR data to successfully characterize the device aging by adopting a little modification in the inverter switching scheme. Included experimental results demonstrate that the proposed method can reduce the number of accessible nodes for performing the state of health (SOH) monitoring of all individual devices used in a three-phase inverter, which will eliminate the need for a separate SOH monitoring module for each device. In addition, due to SSTDR's ability to be embedded in the gate signal, the proposed technique can be integrated with the gate driver module, thus making it intelligent.
Research on the Operation State of Large Nuclear Power Unit under the Fault of 500kV Power System

Power grid fault will cause the frequency and voltage fluctuation of the nuclear power plant, which will directly affect the operation status of the coolant pump and the heat dissipation blade of the nuclear power unit. When the fluctuation degree exceeds the maximum allowable range of nuclear power equipment, may cause the nuclear power plant damage. In order to study the operation status of large-scale nuclear power plant equipment under grid failures, this article focuses on nuclear power plants in a certain area. A 500 kV grid model including pressurized water reactor(PWR) nuclear power plants is built on the PSCAD/EMTDC platform. The custom details of nuclear power plants are detailed The model includes reactor core, steam generator, steam turbine module, etc. The model can reflect the internal dynamic characteristics of nuclear power plant equipment in the event of a grid failure. By simulating the impact of voltage and frequency disturbances on nuclear power plants in the case of grid faults, the disturbance tolerance threshold for the safe operation of nuclear power plants is given, and equipment protection measures in the event of a three-phase short-circuit fault in the power grid are proposed, which is the fault ride-through of nuclear power plants. Further research on capabilities has laid the foundation.
Bridging adsorption analytics and catalytic kinetics for metal-exchanged zeolites

Metal-exchanged zeolites have been widely used in industrial catalysis and separation, but fundamental understanding of their structure–property relationships has remained challenging, largely due to the lack of quantitative information concerning the atomic structures and reaction-relevant adsorption properties of the embedded metal active sites. Here, we report on using low-temperature reactive adsorption of NO to titrate copper-exchanged ZSM5 (Cu-ZSM5). Quantitative descriptors of the atomic structures and adsorption properties of Cu-ZSM5 are established by combining atomistic simulation, density functional theory c, operando molecular spectroscopy, chemisorption and titration measurements. These descriptors are then applied to interpret the catalytic performance of Cu-ZSM5 for NO decomposition. Linear correlations are established to bridge low-temperature adsorption analytics and high-temperature reaction kinetics, which are demonstrated to be generally applicable for understanding the structure–property relationships of metal-exchanged zeolites and foregrounded the development of advanced catalytic materials. Understanding the structure–property relationships of metal-exchanged zeolites is a challenging task. Here, correlations are established between the adsorption properties of Cu-exchanged ZSM5 and the reaction kinetics of NO decomposition, generating descriptors of general applicability to different zeolites.
Ferrimagnetic insulators for spintronics: Beyond garnets

Ferrimagnetic insulators have gained much attention as material platforms with efficient magnetization dynamics. To date, epitaxial iron garnet thin films are the most widely used materials in the emerging field of “insulator spintronics.” However, further advances in this field require overcoming the disadvantages of garnets—e.g., their complex structure, high growth temperature, incompatibility with other crystalline materials, and relatively weak perpendicular magnetic anisotropy. In this Perspective, we make the case that epitaxial thin films of spinel ferrites and hexagonal ferrites are viable materials for insulator spintronics with complementary advantages over the oft-used garnets. Specifically, spinel ferrites have a simpler structure, can crystallize at lower temperatures, and are more amenable to coherent integration with various materials; hexagonal ferrites possess enormous perpendicular anisotropy of bulk origin, in contrast to garnets where the strength of anisotropy is restricted by interfacial strain. The expanded repertoire of materials for insulator spintronics will enable new physical insights and potential applications, beyond what is currently possible with garnets.