cssi/SciSciGPT-SciSciNet huggingface dataset:
Body-Image Attitudes and Psychosocial Functioning in Euro-American and Asian-American College Women:

Euro-American (n = 94) and Asian-American (n = 72) college women were compared on multiple dimensions of body image, including global body satisfaction, preoccupation with appearance, satisfaction with individual body parts or features, and weight concern, and psychosocial functioning, including self-esteem, public self-consciousness, social anxiety, and public body consciousness. Both groups reported similar scores on these variables and showed similar patterns of correlations between body-image and psychosocial variables. Despite similar global body satisfaction, there were group differences in satisfaction with individual body parts or features, with Asian-American women reporting lower satisfaction with six parts or features and higher satisfaction with one feature. Stepwise multiple regression analyses predicting global body satisfaction from individual body parts or features suggested that both the specific body parts or features most salient to global body satisfaction and the relative influence of these parts or features varied as a function of ethnicity. Implications of these findings for research and practice are discussed.
Zero-Dimensional Subrings of Commutative Rings

We consider various conditions of the sets of zero-dimensional, Artinian, and von Neumann regular subrings of a commutative ring. Section 1 treats questions of existence of such rings, Section 2 deals with the situation in which all subrings belong to one of the three classes, and Section 3 is concerned with the behavior of the sets under intersection. In Section 4 we give a brief survey of some generalizations and extensions of results of Sections 1–3, as well as some related results.
Digital Forensics Curriculum in Security Education

Information Security curricula usually cover traditional security topics such as network security, cryptography, and operating system security. As individuals and businesses have come to rely more heavily on computing technology, criminals also have turned their attention to such technology. Consequently, security requires developing adequate policies to protect the information assets, as well as gathering suitable evidence in case the matter ends in a court. Rapid advancements in storage technology have contributed to storing large volumes of data in small devices. Such devices could be hidden with criminal intent or are prone to being lost, thus exposing confidential information. In either case, we need to expose the students specializing in security education to both the technology and the legal aspects.
Providing subject access to images : A study of user queries

This paper describes a study of user queries conducted at two historical photographic collections—the North Carolina Collection at the University of North Carolina at Chapel Hill, and the North Carolina State Archives in Raleigh. Patron requests were analyzed in order to determine which types of subject terms and attributes of images are used most often in requests for photographs. Basic categories of terms were created, and the number of requests utilizing each category of term was tallied. It was found that subject terms, both generic and specific, were used far more frequently than any other categories of terms in requests for photographs. Generic subject terms appeared most often in requests, indicating the importance of these terms for indexing. Time and place were the next most commonly used types of terms. In contrast, genre, visual terms, format, and creator/provenance were mentioned relatively infrequently.
Sub-scale Machining of Large Components☆

Abstract A post-processing algorithm for CNC machine NC code was developed for altering NC code based on measurements from a stand-alone coordinate metrology system that measures the orientation and offset of the part and machine coordinate systems (CS). With this post-processing algorithm, the ability to machine a monolithic part larger than the working area of a machine in multiple sections becomes possible. A series of test parts were machined with a Haas Vertical Milling Machine (VMM) and a Leica laser tracker as proof of concept and to determine the errors introduced into the machining process by adding the additional metrology system. Monte Carlo simulations confirm that adding the stand-alone metrology system increases the magnitude of errors to approximately the accuracy of the metrology system itself, about 50 micrometers. The initial set of test parts machined showed errors at a factor of 25 larger than expected. It was determined that a component used to determine the machine's spindle location was introducing significant error into the process. The component was replaced and new parts machined that showed a significant improvement but still with errors larger than expected. Machine squareness errors showed the importance of measuring CS features within the same plane. Finally, it was determined that the definition of the part CS is sensitive to how the part is fixtured to the machine. Sub-scale machining is a viable process for machining large components with a slight increase in feature location error.
Effect of viral upper respiratory tract infection on cough reflex sensitivity

Acute viral upper respiratory tract infection (URI; common cold) is among the most common medical conditions affecting man, with cough being a typical feature of the associated syndrome. Studies employing capsaicin inhalation challenge to measure cough reflex sensitivity have demonstrated a transient tussive hyperresponsiveness induced by URI that reverts to normal by 4-8 weeks post infection. Mechanisms proposed to explain the induction of cough by URI include a number of infection-associated airway effects, such as enhanced release of cytokines, neurotransmitters, and leukotrienes; increased neural receptor levels; reduced activity of neutral endopeptidases; transient modulation of afferent neural activity; mucus hypersecretion; and, possibly, effects on cholinergic motor pathways. Recent studies evaluating urge-to-cough (UTC), the sensation of irritation preceding the motor act of coughing, have demonstrated that URI induces a transient enhancement of UTC analogous to the effect observed on cough reflex sensitivity. The recently introduced concept of the Cough Hypersensitivity Syndrome may provide an explanation for the commonly observed clinical phenomenon of acute viral URI triggering what will develop into chronic, refractory cough in a subgroup of patients.
Analytical Solution of the Dilute Strain Concentration Tensor for Coated Cylindrical Inclusions, and Applications for Polymer Nanocomposites

Recently nanoparticle-reinforced polymer nanocomposite materials, comprised of the inclusion, (non-bulk polymer) interphase and the bulk polymer matrix, have received considerable interest. Because of interaction between the nanoinclusion and surrounding polymer matrix, the non-bulk polymer in the vicinity of the nanoinclusion has different properties than the bulk polymer. With tremendous amount of surface area, the interphase may have a large influence on the overall nanocomposite properties and complicate micromechanical predictions of effective properties. Although several micromechanical approaches can provide approximations of the effective elastic modulus, they require one to calculate the dilute concentration tensor using the well-known Eshelby tensor that treat interphase as separate, physically distinct inclusions. However, their elegant solutions are no longer available when the real geometry of the annular interphase must be considered. This work analytically determined the components of the dilute strain concentration tensors for both the inclusion and the interphase by addressing four auxiliary loading cases, which can be directly implemented within standard micromechanical approaches, such as the Mori-Tanaka model, to predict the effective properties of polymer nanocomposites with cylindrical/fibrous nanoinclusions. Comparison of the predictions of the proposed model with predictions based on the traditional Multiphase Mori-Tanaka approach show that differences between the models are largest when the annular interphase region is softer than the matrix material, attributed to the ability of the proposed model to capture the “stress-shielding effect” in the case of the softer annular interphase. In addition, we have examined several sets of experimental data from the literature for both stiff and soft interphase systems to shed further insight on the utility of the proposed model. The model proposed here would provide an important guideline to evaluate the impact of chemical functionalization techniques and other strategies that seek to tailor the properties of the interphase region in nanocomposite materials.Copyright © 2014 by ASME
Future Implications of Debt and Deleveraging in the United States Economy

This paper will take a broad based approach in analyzing the structure of the U.S. economy with a particular emphasis on the disruptive U.S. recession and financial crisis which began circa 2008. The role of the U.S. government and the implications high levels of fiscal debt have on the projected growth path of the U.S. economy will be the primary focus of the paper. The discussion will show that the U.S. has likely entered a new, much more difficult stage in its history of economic growth. The short to medium term growth potential of the U.S. economy has fallen below the trend level established since WWII. The flexibility of the U.S. economy will help foster the necessary adjustments; however, this new era will force difficult fiscal and monetary policy choices that have different implications for different section of the population. The policy makers must recognize the changing dynamics of the U.S. economy and they must be prudent in drafting policy that establishes a stronger foundation for future growth. Younger generations in particular will need to take notice of the decisions being made and plan accordingly as it relates to their spending, saving and investment habits.
Overview and Status of the Star Detector at Rhic

Presented here is the current status of the STAR Detector. STAR is one of the four detectors being constructed at the RHIC cou der facility. The STAR detector is scheduled to have its first engineering run with the RHIC beams about six months from the date of this conference. The STAR project is on schedule and expects to be complete on time.
Genomic cis-regulatory map mining

With the huge amount of biological data produced by recent high-throughput technologies such as ChIP-chip, ChIP-Seq and RNA-Seq, it is essential to use computational methods for data analysis. This thesis developed a series of computation tools to mine critical biological knowledge from large-scale genomic data. Those tools were used to characterize the relationships between regulatory factors and gene expressions across development stages, to uncover the regulation functions from combinatorial bindings of factors, and to discover new genomic annotations. The contributions of this thesis lie in several aspects. First, we developed a unique peak calling method that accurately distinguished adjacent peaks and obtained the correct number of summit positions. Second, we proposed two effective metrics for measuring gene activeness using RNA-Seq data. Third, we enhanced a standard data visualization technique in several ways. Fourth, we conducted a study on two important factors, which led to the categorization of known genes, and a novel approach for new gene prediction. Fifth, we studied the combinatorial bindings of multiple factors, uncovered the most frequently occurring factor sets, and calculated scores to indicate co-binding significances. We also examined the enrichments of factor sets over various types of genomic segments. Last, we mined protein-DNA interactions from positive and unlabeled data using a classification approach.
Sugar-sweetened beverage intake, chromosome 9p21 variants, and risk of myocardial infarction in Hispanics

BACKGROUND Chromosome 9p21 variants are among the most robust genetic markers for coronary artery disease (CAD), and previous studies have suggested that genetic effects of this locus might be modified by dietary factors. Intake of sugar-sweetened beverages (SSBs), which are the main dietary source of added sugar, has been shown to interact with genetic factors in affecting CAD risk factors such as obesity. OBJECTIVE We aimed to test whether SSB intake modified the association between chromosome 9p21 variants and CAD risk in Hispanics living in Costa Rica. DESIGN The current study included 1560 incident cases of nonfatal myocardial infarction (MI) and 1751 population-based controls. Three independent single nucleotide polymorphisms (SNPs) at the chromosome 9p21 locus were genotyped. SSB intake was assessed with the use of a food-frequency questionnaire and was defined as the frequency of intake of daily servings of sweetened beverages and fruit juice. RESULTS We showed a significant interaction between SSB intake and one of the 3 variants (i.e., rs4977574) on MI risk. The per–risk allele OR (95% CI) of rs4977574 for MI was 1.44 (1.19, 1.74) in participants with higher SSB consumption (>2 servings/d), 1.21 (1.00, 1.47) in those with average consumption (1–2 servings/d), and 0.97 (0.81, 1.16) in subjects with lower consumption (<1 serving/d; P-interaction = 0.005). A genetic risk score derived from the sum of risk alleles of the 3 SNPs also showed a significant interaction with SSB intake on MI risk (P-interaction = 0.03). CONCLUSION Our data suggest that unhealthy dietary habits such as higher intake of SSBs could exacerbate the effects of chromosome 9p21 variants on CAD.
Landslide Risk Reduction in the United States—signs of Progress

Scientific literature is replete with papers describing advances in applying new technologies to the study of landslides and advances in our understanding of factors affecting landslide occurrence, distribution, and movement. Far fewer papers look at how this knowledge is implemented to achieve landslide risk reduction. State and local governments exercise the greatest control on how landslide risk reduction is accomplished. Data generated from a questionnaire to state geological surveys, review of their agency Web sites, and two case studies demonstrate that progress has been made during the last 20 years in implementing actionable policy changes and programs to achieve a reduction is landslide risk in the United States. Progress is evident from the pivotal role played by state and local government in the areas of: (1) developing guidelines and training, (2) increasing public awareness and education, (3) implementing loss reduction measures, and (4) conducting emergency preparedness, response, and recovery. The number of states requiring registration for practicing geologists has nearly doubled during the last 20 years. This increase was accompanied by a shift from individual state tests as part of determining competency to a uniform national test. During this period, state geological surveys established Web sites as a primary means for promoting public awareness and education about landslide hazards. Measures reducing the impact of landslides have included providing information specific to residents and landowners, as well as supporting land-use planning efforts by local governments. Many state geological surveys are involved with emergency management of landslide hazards.
Analysis of the specifications and editorial quality of Chinese core journals of three main disciplines of universities

In order to enhance the responsibility sense of editors, the construction of editorial normative and editorial quality of university journals and Chinese core periodicals, the editor's mission of offering scientific, normative, readable, economical products; to establish and perfect technological normative; to provide selection basis for core journals; to show the "Piloting" function for core periodicals' editing normative, quality and strengthen the significance of core periodicals; to further the transmission ordering of scientific information and build large journal database, enhance the comparability, generality and standardization of data, and hasten the modernization of China's journal information and bibliometrics research, this paper has performed a survey and analysis based on Chinese Core Journals, according to the 144 universities' journals listed by A Guide to the Core Journals of China, including Natural Sciences(86 journals), Agricultural Sciences (28 journals) and Industry Technology (30 journals), randomly selecting 864 papers from CNKI. In this paper, the analysis includes the problems of university journals in "title, abstract,Keywords, introduction, units, figures, tables, mathematical signs and equations, expressions and references". All together 87 phenomena and problems in editing normative and quality are listed and 7 suggestions are given, which include "emending Editing-Typeset Regulations on Natural Sciences Journals of China's Colleges and Universities, establishing normative inspection and reviewing of journal papers, establishing the random inspection for famous journals, strengthening supervision, making the normative of journals as a required criteria for evaluation".
Oral fluoroquinolone treatment was not associated with serious arrhythmia

Source Citation Inghammar M, Svanstrom H, Melbye M, Pasternak B, Hviid A. Oral fluoroquinolone use and serious arrhythmia: bi-national cohort study. BMJ. 2016;352:i843. 26920666
Funding, Financing, and Investing in Integrated Early Childhood Mental Health Services in Primary Care Settings

Integrating early childhood mental health services into primary care settings holds promise for increasing access to high quality healthcare services. Such services have the potential to prevent the development of later difficulties, promote health and well-being, identify early difficulties and address them when they first emerge, and treat disruptions and disorders in early childhood, including family-level factors that impact development. Establishing sustainable integrated early childhood behavioral health services requires leveraging resources and braiding and blending funding streams to create a comprehensive model of care that will meet the needs of young children and their families. Long-term sustainability depends upon advancing the “Four Ps”: procedures, practice, payment, and policy. This chapter details procedures for service delivery and billing that comply with healthcare regulations and allow continued growth and program innovation and characterizes the unique elements within the practice of integrated early childhood mental health services including a focus on prevention, health promotion, and universal access to high-quality care. In the current landscape of rapid healthcare reform and transformation, payment and compensation for services rendered and future innovations in service delivery are integrally linked to policy changes that are designed to secure integrated early childhood services. Beyond fee-for-service options, truly sustainable integrated early childhood behavioral health will likely rely on bundled payment models where early childhood mental health services are packaged within high-quality primary care for children, and capitated/per member per month (PMPM) rates reflect investments in prevention, health promotion, psychosocial screening processes, and interventions.
A Review of Primary Caesium Clock Development and Satellite Time Comparison Techniques at NRC

The National Research Council of Canada has been active in the development of long-beam primary caesium clocks since 1973, when it was decided to convert the primary frequency standard, CsV, to continuous clock operation. This conversion was accomplished early in 1975, and since then CsV has functioned continuously, providing the physical realization of the NRC scale of proper time, PT(NRC CsV). The two time scales UTC(NRC) and TA(NRC) are derived directly from this scale. The success with CsV led to the decision, in 1976, to construct three smaller primary caesium clocks, CsVIA, CsVIB, and CsVIC, similar in design to that of CsV. These clocks have been in continuous operation since late 1978, and results reviewed in this paper indicate performance similar to that of CsV.With the development of more accurate clocks, it became of increasing importance to devise better systems of international time comparison based on two-way satellite measurements. Results using a 1-MHz pulse rate for such comparisons are ...
Unilateral Pedunculated Polyp of the Palatine Tonsil

Objective: To report a benign tonsillar lesion presenting as a pedunculated polyp and discuss its diagnosis and management. Methods: Design: Case Report Setting: Tertiary Government Hospital Patient: One Results: A 14-year-old lad presented with a seven-year history of an elongated right tonsillar mass without associated bleeding, pain, dysphagia or obstructive sleep apnea. Physical examination revealed a pedunculated mass about 2 x 1 x 0.5cm in size located in the superior pole. After unilateral tonsillectomy, histopathological examination revealed lymphangectatic lipomatous fibrotic polyp. Conclusion: Lymphangiomatous polyp of the palatine tonsils is an unusual benign lesion of the head and neck. These commonly present as unilateral, polypoidal mass that cannot be clinically differentiated from other benign tonsillar lesions. Tonsillectomy is the recommended surgical approach for both diagnostic and therapeutic purposes. Histopathological study must be done to confirm diagnosis. Keywords: Palatine Tonsil, Pedunculated polyp, Hamartoma, Lymphangioma, Tonsillectomy
Distributed Democracy : SeeClickFix.Com for Crowdsourced Issue Reporting

This document explores one case of the growing Government 2.0 eco-system in the United States of America. SeeClickFix.com (SCF) is a web-based service designed to help citizens report non-emergency issues in their neighborhood. The submissions can be submitted via a web interface, by iPhone, Blackberry and Android reporting apps and a Facebook application. Local government officials receive alerts about submitted issues or can track issues that citizens submitted via the so-called 'Watch Area' they are responsible for. The platform allows for direct feedback mechanisms: Local government officials assign a work order number and can change the status of the repair (from open, in progress, to fixed). Citizens are automatically informed about changes in the status of their reported issues allowing for a full feedback cycle. The service is integrated into the social networking services Twitter and Facebook and provides map-based reporting widgets for government and newspaper websites.
Clinical Features and Management of Subretinal Abscesses Secondary to Methicillin-Resistant Staphylococcus aureus Endogenous Endophthalmitis.

BACKGROUND AND OBJECTIVE To describe the clinical features, management, and immediate outcomes of patients with subretinal abscesses secondary to methicillin-resistant Staphylococcus aureus (MRSA) endogenous endophthalmitis. PATIENTS AND METHODS Eleven eyes of seven patients were identified by retrospective chart review. Demographics, initial presentation, examination findings, imaging, cultures, treatments, and short-term outcomes were reviewed. RESULTS Eleven eyes of seven patients presented with subretinal abscesses secondary to MRSA endogenous endophthalmitis. Four had history of recurrent MRSA infections or active soft-tissue ulceration. Six underwent vitreous tap for culture without growth. Three had positive blood cultures for MRSA. Six received empiric therapy with intravenous vancomycin, one received oral trimethoprim-sulfamethoxazole, and six received intravitreal vancomycin. Consolidation of abscesses was seen within days of initial treatment. Visual outcomes were contingent on abscess location and time to initial treatment. CONCLUSION Prompt diagnosis and systemic antibiotic therapy is paramount in the treatment of this rare presentation. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:134-142.].
Abstract 2224: The Relationship Between Process and Outcomes for Stroke Post Prospective Payment in Inpatient Rehabilitation Facilities

Background and Objective: Previous studies have reported decreasing length of stay (LOS) for inpatient rehabilitation facilities (IRFs), with conflicting effects on discharge Functional Independence Measure (FIM) scores and discharge destination (DD). This study was the first to examine the post prospective payment system (PPS) period using Medicare data drawn from the national Inpatient Rehabilitation Facility Patient Assessment Instrument (IRF-PAI) database. The purposes were to examine trends over time for process and outcome factors, and to describe the relationships between process, LOS, and outcomes (discharge FIM scores and DD), for Medicare patients with stroke. Methods: The study included 371,211 Medicare Part A beneficiaries aged 65 and older with stroke, admitted to United States (US) IRFs between January 1, 2002 and June 30, 2007. Descriptive statistics and generalized estimating equations (GEE) modeling for clustered data were used for analysis. Continuous GEE evaluated LOS and discharge FIM scores, and binomial GEE evaluated LOS and DD (community verses institution). Covariates in models were: admission FIM scores, age, gender, race/ethnicity, comorbidities, complications, and stroke type. Time interactions with admission FIM scores, LOS, and discharge FIM scores (binomial model only) were examined. Results: During the study period, mean LOS decreased from 17.9 (SD=9.9) to 16.1(SD=8.3) days (p<. 0001), mean discharge FIM scores decreased from 80.1 (SD=24.5) to 76.5 (SD=24.5) points (p<. 0001), and rate of community discharge decreased from 66.6% to 61.2% (p<. 0001). LOS predicted discharge FIM scores (95% CI, .48, .52, p<.0001), but the relationship to community discharge was weak (OR .997, p=.007). Discharge FIM scores predicted discharge destination (OR 1.07, p<.0001). Covariates of admission FIM scores, age, gender, race/ethnicity, comorbidities, complications, and stroke type also predicted outcomes. Time interactions were present for LOS, admission FIM scores, and discharge FIM scores. Conclusions: During the first 5.5 years of PPS, declining trends were found for LOS, discharge FIM scores, and rate of community discharge for Medicare beneficiaries with stroke. LOS was a strong predictor for discharge FIM scores, but weak for DD. Discharge FIM scores were a better predictor of DD than LOS. Effects of covariates on discharge FIM scores and DD have clinical implications for IRF stroke rehabilitation in the US. Because of the reduced time for treatment, dose of IRF rehabilitation for Medicare beneficiaries may not be achieving expected results in the post-PPS period.
Environmental Protection—TVA Experience

TVA has been engaged in environmental protection since the agency was created in 1933. This resulted from TVA's responsibility for development and protection of the resources in the Tennessee Valley and for improvement in agricultural practices and education. Several environmental protection projects are carried out as parts of the program for agricultural development and power plant operation. These include studies of nuisance weed growth in reservoirs, measurement of nutrient discharge from agricultural lands, development of fly ash control methods, research on sulfur dioxide removal from power plant stack gases, and investigation of environmental effects of waste heat from nuclear power plants. Environmental protection is demonstrated at fertilizer production units operated by TVA. Also, other fertilizer producers are assisted with environmental problems, some TVA fertilizers possess properties useful in control of wastes in air. In cooperation with another government agency, treatment and utilization of municipal waste as a soil amendment is being investigated. The examples of environmental protection projects show the broad scope of environmental protection work carried out by TVA.
Some unique surface patterns on ignimbrites on Earth: A “bird's eye” view as a guide for planetary mappers

Abstract Observations of terrestrial analogs are critical to aiding planetary mappers in interpreting surface lithologies on other planets. For instance, the presence of ignimbrites on Mars has been debated for over three decades and is supported by analogy with deposits on Earth. Critical evidence includes the geomorphic and surface expression of the deposits, and those in the Central Andes of South America are amongst the most-cited analogs. Herein we describe some prominent surface textures and patterns seen in ignimbrites on the scale of high-resolution remotely sensed data (10–1 m per pixel). These include pervasive joints and fractures that contribute to yardang form and development as well as prominent mounds, fissures, and fracture networks (“spiders”, “bugs”, “boxworks”) on ignimbrite surfaces. While all these features are related to intrinsic cooling and degassing processes, the involvement of external water buried by hot pyroclastic flows enhances fumarolic activity, advective cooling, and joint development. Observations of these geomorphic expressions using remote sensing are only possible with the highest resolution data and limited surface erosion. For Mars, where similarly high resolution datasets are available (for example, the High Resolution Imaging Sensor Experiment or HiRISE) extensive dust cover may limit the recognition of similar features there. However significant relief on some of these features on Earth indicate they might still be detectable on Mars.
Parasocial Interactions with Basketball Athletes of Color in Online Mediated Sports

ABSTRACTA two (Black athlete vs. Asian athlete) by two (Black viewer vs. Asian viewer) by two (male vs. female) mixed factorial experiment was designed to examine sports viewers’ parasocial interaction (PSI) with basketball athletes of color. Results found that sports viewers were more likely to exhibit higher PSI when viewing athletes who belonged to their same racial group than viewing those from another racial group. Black viewers showed higher PSI with Black athlete than with Asian athlete. Correspondingly, Asian viewers reported higher PSI with Asian athlete than with Black athlete. Evidence for similarity identification suggested that the more similar media viewers were to media characters, the more likely media viewers were to develop affective bonds with media characters. In the context of online mediated sports, these affective bonds would direct sports viewers to desire greater similarity to athletes, activate them to take athletes’ perspective, and eventually lead them to higher PSI with athlet...
Cognitive Radio Networking with Cooperative Relaying and Energy Harvesting

Cognitive radio networks with energy harvesting result in efficient use of both energy and spectrum. By using cooperative relaying, another feature can be achieved, which is the high diversity gain. In this paper, an energy harvesting underlay cognitive radio relaying network is investigated. In this underlay cognitive radio scheme, secondary users are allowed to access the spectrum, respecting a certain primary interference threshold. The secondary nodes employ decode-and-forward relaying in order to maximize the total received data by optimizing their transmit powers. In this context, both the secondary source and relay harvest energy from renewable sources and store it in finite batteries. They are also capable of buffering data in infinite capacity buffers. We derive closed form expressions for transmit power of secondary source and relay that maximize the secondary network throughput. Projected subgradient method is used to find the power allocated to the secondary network. Numerical simulations are conducted to study the performance of the proposed system. Comparisons are made between the proposed system and other conventional scenarios, and it is observed that when the required signal-to interference-plus-noise ratio (SINR) at the primary receiver is high, the proposed harvesting- based scheme and conventional-based scheme perform similarly.
Hematopoietic stem cell mobilization with plerixafor in sickle cell disease

After more than a half-century since the molecular basis for sickle cell disease (SCD) was described by Linus Pauling and colleagues, we now possess the molecular tools to contemplate a one-time cure through genetic modification of autologous hematopoietic stem cells (HSC). For these promising gene
Technical Note: Distribution of Initial Current Between Bare and Filmed Surfaces: What Is Being Measured in a Scratched Electrode Test?

Abstract To aid in understanding the contribution of the large filmed surface to the measured initial current transient in a scratched electrode test, an in situ fracture technique was used to determine the distribution of currents between the bare and filmed surfaces following the sudden introduction of the bare surface under potentiostatic control. Measurements were made on a 304 stainless steel in deaerated 3.5 percent NaCl solution at room temperature and showed strong influence of the filmed surface on the measured initial current transient. The results support the earlier conclusion that the bare-surface current densities and repassivation kinetics in the literature, based on scratched electrode measurements, are significantly overstated and need to be re-examined.
Coumarinic acid-based cyclic prodrugs of opioid peptides that exhibit metabolic stability to peptidases and excellent cellular permeability

Purpose. To evaluate the cellular permeation characteristics and the chemical and enzymatic stability of coumarinic acid-based cyclic pro-drugs \(\underset{\raise0.3em\hbox{$\smash{\scriptscriptstyle-}$}}{1} \) and \(\underset{\raise0.3em\hbox{$\smash{\scriptscriptstyle-}$}}{2} \) of the opioid peptides [Leu5]-enkephalin (H-Tyr-Gly-Gly-Phe-Leu-OH) and DADLE (H-Tyr-D-Ala-Gly-Phe-D-Leu-OH), respectively.
Impact of fossil fuel emissions and particulate matter on pulmonary health.

In recent decades, several national and international legislative efforts have aimed to improve air quality standards and limit major pollutants, such as carbon monoxide, sulfur dioxide, and nitrog...
Optimizing Size of Lithium-Ion Battery Combined with PV Generation

Lithium-ion batteries have been popular partners of photovoltaic (PV) arrays for more efficient utilization of solar energy. Although the lithium-ion battery price shows a continuously decreasing trend, it is still a challenge to deploy a cost-effective lithium-ion battery energy storage system (BESS) without financial incentives, especially for attaining higher profits. In order to maximize the profit of a lithium-ion BESS combined with a PV array, we proposed a two-stage stochastic optimization model that simultaneously determined the optimal size, charging and discharging schedules of the lithium-ion BESS. We considered that the PV-BESS could earn multi-source benefits by participating in the energy market, shaving the peak load demand, and alleviating power deviations from the forecast. Additionally, the capacity degradation of the lithium-ion battery was incorporated to estimate its lifetime and total revenue over its lifespan. The objective of our model is to maximize the BESS profit, i.e., total revenue minus cost. The BESS profit was formulated as a nonlinear function of the planning stage variable (battery size) and the operation stage variables (charging and discharging schedules). The optimization results suggested a trade-off between daily revenue and battery lifetime through optimizations of battery size and charging and discharging schedules.
Evaluation of X-Linked Adrenoleukodystrophy Newborn Screening in North Carolina

Importance X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal genetic disorder in which an accumulation of very long-chain fatty acids leads to inflammatory demyelination in the central nervous system and to adrenal cortex atrophy. In 2016, X-ALD was added to the US Recommended Uniform Screening Panel. Objective To evaluate the performance of a single-tier newborn screening assay for X-ALD in North Carolina. Design, Setting, and Participants This diagnostic screening study was of all newborn dried blood spot specimens received in the North Carolina State Laboratory of Public Health between January 2 and June 1, 2018, excluding specimens of insufficient quantity or quality. A total of 52 301 specimens were screened for X-ALD using negative ionization high-performance liquid chromatography tandem mass spectrometry to measure C24:0- and C26:0-lysophosphatidylcholine concentrations. Sanger sequencing of the adenosine triphosphate–binding cassette subfamily D member 1 (ABCD1) gene was performed on screen-positive specimens. Exposures A medical and family history, newborn physical examination, sequencing ofABCD1on dried blood spot samples, and plasma analysis of very long-chain fatty acids were obtained for all infants with screen-positive results. Main Outcomes and Measures The prevalence of X-ALD in North Carolina and the positive predictive value and false-positive rate for the first-tier assay were determined. Results Of 52 301 infants tested (47.8% female, 50.6% male, and 1.7% other or unknown sex), 12 received screen-positive results. Of these 12 infants, 8 were confirmed with a genetic disorder: 3 male infants with X-ALD, 3 X-ALD–heterozygous female infants, 1 female infant with a peroxisome biogenesis disorder, and 1 female infant with Aicardi-Goutieres syndrome. Four infants were initially classified as having false-positives results, including 3 female infants who were deemed unaffected and 1 male infant with indeterminate results on confirmatory testing. The positive predictive value for X-ALD or other genetic disorders for the first-tier assay was 67%, with a false-positive rate of 0.0057%. Conclusions and Relevance This newborn screening pilot study reported results on 2 lysophosphatidylcholine analytes, identifying 3 male infants with X-ALD, 3 X-ALD–heterozygous female infants, and 3 infants with other disorders associated with increased very long-chain fatty acids. These results showed successful implementation in a public health program with minimal risk to the population. The findings will support other state laboratories planning to implement newborn screening for X-ALD and related disorders.
Dual-process contributions to creativity in jazz improvisations: An SPM-EEG study

Abstract Conflicting theories identify creativity either with frontal-lobe mediated (Type-2) executive control processes or (Type-1) associative processes that are disinhibited when executive control is relaxed. Musical (jazz) improvisation is an ecologically valid test-case to distinguish between these views because relatively slow, deliberate, executive-control processes should not dominate during high-quality, real-time improvisation. In the present study, jazz guitarists (n ​= ​32) improvised to novel chord sequences while 64-channel EEGs were recorded. Jazz experts rated each improvisation for creativity, technical proficiency and aesthetic appeal. Surface-Laplacian-transformed EEGs recorded during the performances were analyzed in the scalp-frequency domain using SPM12. Significant clusters of high-frequency (beta-band and gamma-band) activity were observed when higher-quality versus lower-quality improvisations were compared. Higher-quality improvisations were associated with predominantly posterior left-hemisphere activity; lower-quality improvisations were associated with right temporo-parietal and fronto-polar activity. However, after statistically controlling for experience (defined as the number of public performances previously given), performance quality was a function of right-hemisphere, largely right-frontal, activity. These results support the notion that superior creative production is associated with hypofrontality and right-hemisphere activity thereby supporting a dual-process model of creativity in which experience influences the balance between executive and associative processes. This study also highlights the idea that the functional neuroanatomy of creative production depends on whether creativity is defined in terms of the quality of products or the type of cognitive processes involved.
Adipose‐resident myeloid‐derived suppressor cells modulate immune cell homeostasis in healthy mice

The metabolically dynamic nature of healthy adipose places this tissue under regular inflammatory stress. A network of adipose-resident anti-inflammatory immune cells modulates and resolves this endogenous inflammation. Previous work in our laboratory identified a CD11b+ Gr1+ subset of these immunosuppressive adipose stromal cells in healthy mice. Myeloid-derived suppressor cells (MDSCs), typically associated with cancer and chronic inflammation, have a similar surface marker phenotype and accumulate in adipose of high-fat diet-fed mice. Given the routine inflammatory stresses on healthy adipose and the suppressive nature of the tissue-resident immune cells, we hypothesized that these CD11b+ Gr1+ cells were a genuine population of MDSCs involved in regulating tissue homeostasis. Flow cytometric analysis of these cells found that they were CD11b+ CD301- Ly6C+ Ly6G+/- and did not express traditional macrophage markers. Moreover, in vitro functional assays demonstrated that these cells suppressed αCD3/αCD28-induced T-cell proliferation, solidifying their identity as bona fide adipose-resident MDSCs. Systemic MDSC depletion altered adipose immune cell dynamics in otherwise healthy mice, increasing the number of CD4+ effector memory T cells and modifying the surface markers expressed by adipose-resident macrophages. In addition, transcription of various immunomodulatory cytokines was clearly dysregulated in the adipose of MDSC-depleted animals compared with controls. Altogether, our findings indicate that there is a population of bona fide MDSCs in the adipose of otherwise healthy mice that actively contribute to the health and immune homeostasis of this tissue.
Inter-individual differences in immune profiles of outbred rats screened for an emotional reactivity phenotype.

Abstract Inter-individual differences in emotional reactivity predict susceptibility versus resilience to mood pathology. Using experimentally-naive outbred rats that vary in locomotor reactivity to the mild stress of an inescapable novel environment [i.e., top and bottom 1/3rd of the population identified as high responders (HR) and low responders (LR) respectively], we determined baseline variations in immune functions. Innate and adaptive immune responses vary basally in LRHR rats, namely a shift towards TH1 in LRs and TH2 in HRs was observed. These inter-individual variations in immune profiles in LRHRs could have significant implications in mood alterations and immune reactivity to microbes and cancer.
Buying the hype? Assessing the impact of top-drafted rookies on spectator attendance in the NBA

Recent sports economics literature has focused on ‘superstar effects,’ or the independent impact of certain exceptional players on fan attendance at live events. This paper investigates the effect ...
Evaluating efficacy of a novel dentifrice in reducing probing depths in Stage I and II periodontitis maintenance patients: A randomized, double-blind, positive controlled clinical trial.

Author(s): Kaur, Maninder; Geurs, Nicolaas C; Cobb, Charles M; Otomo-Corgel, Joan; Takesh, Thair; Lee, June H; Lam, Tracie M; Lin, Kairong; Nguyen, Audrey; Nguyen, Brian L; Wilder-Smith, Petra | Abstract: BackgroundCompliance to periodontal maintenance therapy (PMT) is essential for long-term periodontal health. Between PMT visits, patients must maintain good oral hygiene. A dentifrice with demonstrable clinical benefits for use between PMT visits would be highly desirable. The aim of this clinical study was to investigate the effect of a novel dental gel on probing depths (PD) and inflammation when used as a home care dentifrice in Stage I and II periodontitis patients.MethodsThis double-blind clinical study randomized 65 subjects with Stage I and II periodontitis to the novel dental gel containing 2.6% EDTA, and a commercially available anti-gingivitis dentifrice with 0.454% stannous fluoride. Primary endpoint was PD at 6 months for those sites with baseline PD ≥ 4nmm and secondary endpoints included whole mouth mean scores of modified gingival index (MGI), modified sulcus bleeding index (mSBI) and plaque index (PI). No SRP was performed at baseline.ResultsSubjects using the novel dentifrice showed significant PD reductions of 1.18nmm (from 4.27nmm at baseline to 3.09nmm at 6 months) compared to 0.93nmm (from 4.23nmm at baseline to 3.30nmm at 6 months) shown for those using the positive control dentifrice. Difference between treatments at 6 months was 0.21nmm with P-valuen=n0.0126. Significant improvements in MGI (Pn=n0.0000), mSBI (Pn=n0.0000), and PI (Pn=n0.0102) were also observed in 6 months.ConclusionThe novel dentifrice showed significant reductions in PD and gingival inflammation over 6 months solely as a home care dentifrice without baseline SRP in Stage I and II periodontitis maintenance patients.
Improving harm reduction with a naloxone intervention in primary care to prescribe and educate a support person

Objective: To determine whether a pharmacist-led intervention would increase the number of naloxone prescriptions and naloxone administration education in a primary care family medicine setting. Design: Prospective quality improvement intervention in an academic family medicine clinic. Methods: We surveyed providers about naloxone knowledge, prescribing habits, and prescribing barriers. We identified patients on chronic opioid therapy, through electronic health records for the year 2019. Overdose risk categories based upon morphine milligram equivalent doses and concomitant benzodiazepine use were used to determine patients who met criteria for naloxone. Pharmacists phoned qualified patients to discuss overdose risk and naloxone benefits. Patients who accepted naloxone prescriptions used their local pharmacy through a department-approved standing order set. Results: From the survey results, there were 47 of 54 provider responses, and the majority noted that they do not routinely prescribe naloxone in high-risk patients. The predominant barriers were lack of time during visit and naloxone administration education. The population of patients from chart review included 93 high-risk patients with a mean age of 58 years. During the time of intervention, 71 patients remained eligible for naloxone coprescribing. Of the patients contacted, 29 (40 percent) accepted the intervention prescription, and subsequently, 22 picked up their prescription from the pharmacy. Sixteen received counseling with a support person. Twelve patients had naloxone already at home, and two received counseling with a support person. Conclusion: The naloxone prescribing intervention is achievable. The results of this intervention support identifying patients at increased risk of opioid overdose and offer education of a support person for naloxone in a large academic family medicine clinic.
Real-Time Analytics

With the advent of big data, the competition for many businesses is to extract the actionable insights and do it fast. The streaming nature of big data requires equally performing the analytics in near real time. The many advances in technology from bigger storage capacity to faster processing power make it more possible to reach that goal. Conducting the analytics in near real time raises fundamental questions on how to ensure the integrity of the results while accommodating the need to go back in time, and conduct a postmortem investigation in case the results are wrong. If the data is changing in real time, unless we maintain some history of the data, it is almost impossible to determine whether the source of a problem is due to the data or to the analytics. Rules in place for data governance, and auditing of the analytics will have to change.
The Role of ZrO2 Powders in Microstructural Development of PZT Ceramics

Processing electrical ceramics to obtain reproducible properties is not an easy task. Seemingly inconsequential changes in raw materials or processing steps can produce ceramics with quite different properties.