cssi/SciSciGPT-SciSciNet huggingface dataset:
Evaluation of tunnel face stability by transparent soil models

Accurate estimation of tunnel face support pressure is necessary for economical and safe shield tunneling in cohesionless soils. This paper presents measurements of tunnel face support pressure and associated soil movements obtained using a transparent soil model that simulates shield tunneling in medium dense saturated sand. The use of a transparent soil surrogate permits measuring the internal soil deformations within the model soil. Soil deformations associated with various face support pressures are presented for 4 cover-to-diameter (C/D) ratios. Failure is found to be sudden with sand flowing into the tunnel leading to a prismatic wedge in front of the tunnel face and a vertical chimney of soil above. A minimum support pressure was achieved with support pressures as low as 10 ± 1% of the effective vertical stress at the tunnel axis. The stability of the tunnel face was related to the coefficient of active earth pressure with C/D ratio having a small effect on the magnitude of required pressure at collapse.
Isolation and characterization of a candidate gene for progressive myoclonus epilepsy on 21q22.3

The Unverricht-Lundborg type of progressive myoclonus epilepsy (EPM1) and autoimmune polyglandular disease type I (APECED) have been mapped to human chromosome 21q22.3 by genetic linkage analysis and/or linkage disequilibrium studies. In order to isolate the genes for these disorders, we have constructed BAC contigs in this region and a 14 week trisomy 21 fetal brain cDNA library. A direct cDNA selection technique, modified to permit the recovery 5' and 3' ends of cDNA, was applied to gene identification using the BAC contigs. We have isolated and characterized a novel gene defined by three overlapping but distinct cDNAs of 5, 3, and 3 kb in size all named EHOC-1 (Epilepsy, HOloprosencephaly Candidate-1). This gene maps less than 45 kb centromeric of D21S25, and spans at least 56 kb of genomic DNA. Northern analysis of the 5 kb cDNA revealed that 8, 7.5 and 5.3 kb transcripts are ubiquitously expressed in adult tissues. DNA sequence analysis of the 5 kb cDNA showed a complete coding sequence of 3570 bp that has multiple putative transmembrane domains and has partial homologies to transmembrane proteins including sodium channel proteins. This gene (EHOC-1) is a good candidate for APECED, and particularly for EPM1 because of the location, size, structure and homologies.
Individual Differences and Day-to-Day Fluctuations in Perceived Self-Regulation Associated With Daily Adherence in Late Adolescents With Type 1 Diabetes

tions in late adolescents’ self-regulation were associated with daily adherence to the type 1 diabetes regimen. Methods 110 school seniors (M age ¼ 17.78 years) and their mothers assessed adolescents’ skills underlying self-regulation (executive function, attention, self-control, behavioral inhibition and activation, emotion regulation) and adherence, with glycosylated hemoglobin from medical records. Teens completed daily diaries reporting self-regulation failures surrounding monitoring blood glucose, adherence, and number of blood glucose checks each day for 14 days. Results Hierarchical Linear Models indicated that better daily adherence was associated with teen and mother reports of better self-regulation skills and teens’ reports of fewer daily self-regulation failures. Daily adherence was unrelated to temperamental differences in behavioral inhibition and activation. Conclusions Results indicate that both individual and intraindividual differences in self-regulation contribute to daily adherence highlighting the importance of daily self-regulatory challenges to adherence.
Primary T-Cell–Rich B-Cell Lymphoma of the Ethmoid Sinus

Abstract T-cell–rich B-cell lymphoma (TCRBCL) is an uncommon and recently recognized variant of B-cell non-Hodgkin lymphoma characterized by a few large neoplastic B cells amid a predominant population of reactive T lymphocytes and variable numbers of histiocytes. Morphologically, TCRBCL resembles a variety of non-Hodgkin lymphomas and Hodgkin disease. Accurate diagnosis and proper treatment are essential to assure a favorable prognosis. To our knowledge, this is the first report of ethmoid sinus presentation of TCRBCL in an Epstein-Barr virus–negative 51-year-old man. Combined chemotherapy and radiotherapy were administered based on the correct diagnosis. The patient has had a complete response with no recurrence during the 5-year follow-up.
The Cfo and Performance Measurement

The purpose of this article is to introduce expectations based management (EBM) as an approach that (1) links the company's performance to its total return to shareholders, (2) emphasizes the necessity of clear communication with both external and internal constituencies, and (3) describes how internal performance standards should be established.
A multidimensional gas chromatographic method for analysis of n-butane oxidation reaction products

A multidimensional gas chromatographic (GC) method for on-line analysis of all gas-phase reaction products obtained from the selective oxidation of n-butane to maleic anhydride in an automated catalyst testing reactor is described. A dimethylpolysiloxane megabore column and a multidimensional sequence of packed columns that contain molecular sieve 5A and Hayesep R are shown to provide resolution of n-butane, maleic anhydride, various oxygen-containing byproducts, oxygen, nitrogen, and all total combustion products by using a single temperature programmed GC with simultaneous injection of two gas samples from a multiport valve. For applications where various C 1 -C 4 hydrocarbon byproducts are either known or suspected to be present in the product gas and precise resolution is required, an Al 2 O 3 /KCl PLOT column can be connected to the dimethylpolysiloxane column by using a series-bypass arrangement with a multiport valve. All hydrocarbons and oxygen-containing hydrocarbons are detected with a flame-ionization detector, and a thermal conductivity detector is used for the permanent gases, total combustion products, and n-butane. To quantify the raw GC peak areas, both absolute and relative response factors are also derived for all species by using gas-phase and liquid-phase calibration standards. Comparisons between experimental and theoretical values for the relative effective carbon numbers of maleic anhydride with those of n-butane are also used to confirm that solute adsorption is linear and reversible on the selected megabore column. Effective carbon numbers for the other analytes detected by the flame-ionization detector are also derived and compared with the theoretical values. Statistical characterization of the response factors and effective carbon numbers is also performed so that an assessment of the errors associated with any derived quantities in future applications of the method, such as gas compositions, reactant conversions, and product yields, will be possible. Incorporation of the proposed method into an automated fixed-bed catalyst test facility and typical results obtained for n-butane oxidation to maleic anhydride over a known metal oxide catalyst are also described. Advantages of the proposed technique over previously reported GC methods for analysis of the reaction products from butane oxidation are also suggested.
A longitudinal analysis of cross-border ties and depression for Latino adults

Recent scholarship suggests a significant association between cross-border ties, or ties maintained with family and friends in countries and communities of origin, and the mental health of immigrants and their descendants. To date, this research has been exclusively cross-sectional, precluding conclusions about a causal association between cross-border ties and mental health outcomes. In the present study we undertake a longitudinal analysis of the relationship between cross-border ties and depression measured over a ten-year period for a sample of immigrant and U.S.-born Latinos. Data are from the Sacramento Area Latino Study on Aging (1998-2008), a population-based, prospective study of Latin American-origin adults 60 years and older. We find that cross-border ties reported at baseline were significantly associated with depression in subsequent study waves, even after controlling for the presence of depression at baseline, albeit with substantial differences by gender and nativity. Specifically, communication with family and friends in Latin America and travel to Latin America at baseline were each significantly associated with greater odds of depression for immigrant women, but with lower odds of depression for U.S.-born Latina women over the study period. Travel to Latin America at baseline was significantly associated with lower odds of depression for Latino men across the study. Across all models we control for depressive symptomatology at baseline to account for the reciprocal nature of depressive symptoms and engagement with social ties, including cross-border ties. Our findings suggest that cross-border ties may represent a unique source of both resilience and risk for the long-term mental health of immigrant Latinos and their descendants.
Simulation Operation Mode of Power Grid Based on SCADA and WAMS

The initial simulation operation mode of power grid is one of the main factors influencing calculation results.At present,equipments operated in main power grids are overlaid by SCADA,so the data acquired by SCADA can be used as the main data source to construct power grid's simulation operation mode.However,obvious deviation may exist between the condition of actual power grid and the initial operation mode built by data from SCADA only.Along with the extensive application of wide area measurement system(WAMS)in power grid,the real dynamic power grid data acquired by WAMS also become one of the main data sources of building initial simulation operation mode of power grid.An method to build simulation operation mode,which uses data from SCADA and WAMS,is proposed in this paper,in which the features of both SCADA and WAMS are taking into account and the data flow among SCADA,WAMS and simulation database is determined,so the proposed method possesses a clear definite validating adjustment mechanism.The application results of utilizing the proposed method in Northeast Power Grid show that the built simulation operation mode can successfully withstand the repeated verification by the measured data from SCADA and WAMS.
Survey of indoor γ radiation and residents radiation doses caused by radon in Shijiazhuang City

[Objective]To test the level of indoorγradiation and radon concentration of residential areas in Shijiazhuang City through comparisons with location,building materials,construction age,decoration materials,and to estimates the exposure doses received by the residents.[Methods]FD-3013 B intelligentγ radiometer was used to detect indoor γ radiation level and solid state nuclear track method to was used to measure the cumulative dose of radon concentration.[Results] The mean concentration of indoorγradiation was 0.155 ± 0.023(0.107-0.20)μSv/h and the mean value of radon concentration was[31.8 ±16.5(9.3-111.0) ]Bq/m3in Shijiazhuang City.The highest values were involved in urban areas,high buildings,and rooms decorated by ceramic tiles.The total dose caused by the two radiation sources was 1.60 mSv / a.[Conclusion]The level of indoorγradiation and radon concentration of residential areas in Shijiazhuang City is a normal natural background level.Building materials are the major factors that affect indoor γ radiation levels and radon concentration.Selection of appropriate materials for construction and decoration can reduce radiation doses received by residents,thus reducing its negative impacts on human health.
A Theory of Issue Uptake

The model of uptake described in Chapter 1 requires that legislators recognize and act on their challengers' campaign issues. I proposed that engaging in this behavior is a strategic choice, undertaken by legislators who believe that it will promote their reelection goals. Presumably, all other things being equal, legislators would not choose to act on their challengers' themes, as paying attention to these issues diverts attention from other issues that may be of more intrinsic interest to them. However, to the extent that doing so helps them to accomplish their electoral goals, they have a clear incentive to look to their previous campaign experiences when formulating their agendas. Of course, reelection is not legislators' only goal; they may also want, as Fenno (1973) noted, to make good public policy or to achieve influence in Congress. They may also wish to be good representatives, faithfully reflecting their constituency's interests, apart from any tangible benefit they may receive. Nonetheless, rational legislators should recognize that they cannot achieve these other goals unless they are able to remain in office, and so reelection is, for the majority, the most proximate goal. This idea of the electoral connection, that, while in office, “congressmen must constantly engage in activities related to reelection” (Mayhew 1974, 49), has become central to the study of legislative behavior. The possible mechanisms for this connection are numerous and are discussed in more detail later.
Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson's disease etiology.

Recent genome-wide association studies (GWAS) of Parkinson’s disease (PD) revealed at least 26 risk loci, with associated single nucleotide polymorphisms (SNPs) located in non-coding DNA having unknown functions in risk. In order to explore in which cell types these SNPs (and their correlated surrogates at r2 ≥ 0.8) could alter cellular function, we assessed their location overlap with histone modification regions that indicate transcription regulation in 77 diverse cell types. We found statistically significant enrichment of risk SNPs at 12 loci in active enhancers or promoters. We investigated 4 risk loci in depth that were most significantly enriched (−logeP > 14) and contained 8 putative enhancers in the different cell types. These enriched loci, along with eQTL associations, were unexpectedly present in non-neuronal cell types. These included lymphocytes, mesendoderm, liver- and fat-cells, indicating that cell types outside the brain are involved in the genetic predisposition to PD. Annotating regulatory risk regions within specific cell types may unravel new putative risk mechanisms and molecular pathways that contribute to PD development.
Abstract 3480: Germline PARP4 mutations in patients with primary thyroid and breast cancers

Breast and thyroid cancers occur more frequently in the same individual than what is expected due to random occurrence, implying the presence of genetic susceptible factors. Germline mutations in the PTEN gene, which cause Cowden syndrome (CS), are known to be one of the genetic factors for primary thyroid and breast cancers, however, PTEN mutations are found in only a small subset of research participants with non-syndrome breast and thyroid cancers. In this study, we attempted to identify germline variants that may be related to genetic risk of primary thyroid and breast cancers by whole-exome sequencing. Genomic DNAs extracted from peripheral blood of 14 PTEN-wild-type female research participants with primary thyroid and breast cancers were analyzed. Among them, 7 (50%) and 5 (36%) participants had a family history of thyroid or breast cancer within 3 generations of the proband, respectively. No rare variants were found in SDHx/KLLN/PIK3CA/AKT1 genes previously known to be responsible for CS. We then performed a case-control association study using the information of 406 Europeans obtained from the 1000 Genomes Project database as controls. The predicted impact of amino acid substitutions was annotated using 5 algorithms of LRT score, MutationTaster, PolyPhen-2, HumDiv, PolyPhen-2 HumVar and SIFT. Gene-based association analysis identified 34 genes, including DNA repair-related genes, possibly associated with the phenotype with P Citation Format: Yuji Ikeda, Kazuma Kiyotani, Poh Yin Yew, Taigo Kato, Kenji Tamura, Kai Lee Yap, Jessica L. Mester, Sarah H. Nielsen, Grogan H. Raymon, Charis Eng, Yusuke Nakamura. Germline PARP4 mutations in patients with primary thyroid and breast cancers. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 3480.
Stochastic Games for the Smart Grid Energy Management With Prospect Prosumers

In this paper, the problem of the smart grid energy management under stochastic dynamics is investigated. In the considered model, at the demand side, it is assumed that customers can act as prosumers who own renewable energy sources and can both produce and consume energy. Due to the coupling between the prosumers’ decisions and the stochastic nature of renewable energy, the interaction among prosumers is formulated as a stochastic game, in which each prosumer seeks to maximize its payoff, in terms of revenues, by controlling its energy consumption and demand. In particular, the subjective behavior of prosumers is explicitly reflected into their payoff functions using the prospect theory, a powerful framework that allows modeling real-life human choices, rather than objective, user-agnostic decisions, as normative models do. For this prospect-based stochastic game, it is shown that there always exists a stationary Nash equilibrium where the prosumers’ trading policies in the equilibrium are independent of the time and their histories of the play. Moreover, to obtain one of such equilibrium policies, a novel distributed algorithm with no information sharing among prosumers is proposed and shown to converge to an $\epsilon$ -Nash equilibrium in which each prosumer is able to achieve its optimal payoff in an equilibrium up to a small additive error $\epsilon$ . On the other hand, at the supply side, the interaction between the utility company and the prosumers is formulated as an online optimization problem in which the utility company's goal is to learn its optimal energy allocation rules. For this case, it is shown that such an optimization problem admits a no-regret algorithm meaning that regardless of the actual outcome of the game among the prosumers, the utility company can follow a strategy that mitigates its allocation costs as if it knew the entire demand market a priori . Simulation results justify the convergence of the proposed algorithms and present new insights toward more efficient energy management in the smart grids.
Wireless neutron and gamma ray detector modules for dosimetry and remote monitoring

Compact neutron detectors are being designed and tested for use as wireless low-power real-time personnel dosimeters and for remote neutron sensing. The neutron detectors are pin diodes that are mass produced from high-purity Si wafers. Each detector has thousands of perforations etched vertically into the device. The perforations are backfilled with 6LiF to make the pin diodes sensitive to thermal neutrons. The first prototype devices delivered over 3.8% thermal-neutron detection efficiency while operating at 15 volts. Recent high-efficiency perforated devices have delivered over 20% thermal-neutron detection efficiency. Compact packages with wireless communication capability have been constructed and are under test. The compact packages record counts every second and transmit ten data points every ten seconds. The platforms have been designed to incorporate an additional fast neutron detector and a Frisch- collar CdZnTe gamma-ray spectrometer. The overall goal is to manufacture a compact package capable of remote and wireless neutron dosimetry and gamma ray spectroscopy/dosimetry.
Fission Cross-Section Measurements of 247Cm, 254Es, and 250Cf from 0.1 eV to 80 keV

The fission cross sections of 247Cm, 254Es, and 250Cf are measured with the Rensselaer intense neutron spectrometer from 0.1 eV to 80 keV. The cross sections are normalized to the 235U ENDF/B-V bro...
Eigenfunction Expansions On Semisimple Lie Groups

1. In these lectures it will be my aim to discuss some aspects of the problem of obtaining an explicit Plancherel formula for a connected real semisimple Lie group with finite center, and the close connection of this problem with the theory of eigenfunction expansions on the group. The central results are those of Harish Chandra, and it is impossible to give anything more than a partial outline of his monumental work that began in the early ' 50' s and has spanned almost three decades.
A test of the Δ S =Δ Q selection rule in K μ3 0 decay

A test of the ΔS=ΔQ selection rule in K μ3 0 decay was performed using optical spark chambers. K0-mesons were produced by 3 GeV/c π− in the reaction π−p→ΛK0. 100 events with proper decay times between 0.5 and 6.5 K 0 lifetimes were analysed to give a ratio of the ΔS=−ΔQ to ΔS=ΔQ amplitudes Rex′=0.04 −0.13 +0.10 , Imx′=0.12 −0.16 +0.17 .
The Role of Plant High-Throughput Phenotyping in the Characterization of the Response of High Ascorbate Plants to Abiotic Stresses

l-Ascorbic acid (AsA, ascorbate or vitamin C) is the most abundant water-soluble antioxidant found in plants. Ascorbate is synthesized via four pathways involving d-mannose/l-galactose, d-galacturonate, l-gulose, and myo-inositol as main precursors. In addition to protecting plant tissues from damage caused by reactive oxygen species produced through normal oxygenic metabolism or those generated from biotic and abiotic stresses, ascorbate is also an enzyme cofactor and a modulator of cell division, cell expansion, flowering time, and gene regulation. Plants that are deficient in ascorbate are affected in multiple ways including alterations in cell division, cell expansion, seed germination, growth, floral induction, and photosynthesis. Additionally, elevated ascorbate content in plants leads to an increase in their nutritive value, lengthening of their shelf life, enhancement on their growth rate and biomass accumulation, and to an increased tolerance to multiple abiotic stresses including salt, cold, heat, and water deficit. Increasing the productivity of crops is imperative to satisfy the growing demand for food, feed, and fuels in the world, and biotechnology can lead to the development of plants with higher yields capable of thriving under adverse conditions. To this end, phenotype screening and characterization of a large number of plants experimentally obtained is time consuming and requires a significant amount of resources, skills, and expertise. In this chapter, we will present an overview of how the use of high-throughput phenotyping or phenomics is revolutionizing the way plant phenotypes are characterized and will illustrate the power of digital phenotyping in the characterization of plants overexpressing enzymes in the inositol pathway to ascorbate.
Bone Health in Adolescents with Eating Disorders

Impaired bone health with increased bone fragility is a potentially irreversible complication of eating disorders. Onset of an eating disorder is usually during adolescence, the critical time when peak bone mass is accrued. Adolescents with eating disorders have reduced bone mineral accrual, as well as accelerated bone resorption. Treatment of low bone mineral density remains challenging. Weight gain with resumption of spontaneous menses is associated with increases in bone mineral density, but residual deficits persist. As weight restoration is often a slow process, therapeutic strategies are needed to preserve bone mineral density during eating disorder treatment. Oral estrogen-progestin agents do not increase bone mineral density in adolescents with eating disorders, but physiological doses of transdermal estrogen with cyclic progestin may benefit some patients. The bisphosphonates are effective in adults, but concern about their efficacy and safety in adolescents limits their use. The future role of anabolic agents, bisphosphonates, and other antiresorptive agents remains to be determined. Current recommendations include weight restoration with resumption of spontaneous menses, moderate weight-bearing exercise, optimal calcium and vitamin D intake, and treatment of vitamin D deficiency.
Useful agents for the study of glutathione metabolism in erythrocytes. Organic hydroperoxides

t-Butyl hydroperoxide and cumene hydroperoxide, both known to be substrates for glutathione peroxidase, were used to oxidize erythrocyte GSH. Addition of concentrations of hydroperoxides equimolar with respect to GSH in the erythrocytes or whole blood quantitatively oxidizes GSH in the erythrocytes with a half-time of 4.5s at 37°C and about three times as long at 4°C. In the presence of glucose, normal erythrocytes regenerate all the GSH in about 25min. However, glucose 6-phosphate dehydrogenase-deficient erythrocytes failed to regenerate GSH. Treatment of erythrocytes with hydroperoxides does not affect erythrocyte survival in rabbits. Oxidation of erythrocyte GSH with equimolar concentrations of hydroperoxides does not lead to formation of mixed disulphides of haemoglobin and GSH. The hydroperoxides do not affect erythrocyte glycolytic and hexose monophosphate-shunt-pathway enzymes. Previous studies on transport of GSSG from erythrocytes were confirmed by using t-butyl hydroperoxide to oxidize erythrocyte GSH.
Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs

The purpose of this study was to determine the pharmacokinetics of cannabidiol (CBD) in healthy dogs. Thirty, healthy research dogs were assigned to receive 1 of 3 formulations (oral microencapsulated oil beads, oral CBD-infused oil, or CBD-infused transdermal cream), at a dose of 75 mg or 150 mg q12h for 6 wk. Serial cannabidiol plasma concentrations were measured over the first 12 h and repeated at 2, 4, and 6 wk. Higher systemic exposures were observed with the oral CBD-infused oil formulation and the half-life after a 75-mg and 150-mg dose was 199.7 ± 55.9 and 127.5 ± 32.2 min, respectively. Exposure is dose-proportional and the oral CBD-infused oil provides the most favorable pharmacokinetic profile.
An analysis of fatal log truck crashes in the United States from 2011 through 2015

ABSTRACTAnalyses of data obtained from the United States (US) federally maintained Fatality Analysis Reporting System (FARS) crash database indicated that fatal log truck crashes increased across the US. The reported occurrences of log trucks involved in a fatal crash increased by 41% between 2011 and 2015. Analyses of 383 crashes involving log trucks were performed nationally and regionally. Most log truck crashes (84%) involved tractor-trailer configurations. We also compared fatal crashes using only tractor-trailer vehicle configurations for log trucks versus other tractor-trailer cargo body types. Logging tractor-trailers represent 326 (3.4%) of the 9597 tractor-trailers involved in a fatal crash over the same period. Both logging tractor-trailer and other tractor-trailer crashes increased during the 5-year period. Other large truck crashes increased 19% while log truck tractor-trailer crashes increased by more than 33%. Log trucks were the oldest vehicles involved in fatal crashes, with an average ag...
Bounded, yet Sufficient? How to Determine Whether Limited Side Channel Information Enables Key Recovery

This work presents a novel algorithm to quantify the relation between three factors that characterize a side channel adversary: the amount of observed side channel leakage, the workload of full key recovery, and its achievable success rate. The proposed algorithm can be used by security evaluators to derive a realistic bound on the capabilities of a side channel adversary. Furthermore, it provides an optimal strategy for combining subkey guesses to achieve any predefined success rate. Hence, it can be used by a side channel adversary to determine whether observed leakage suffices for key recovery before expending computation time. The algorithm is applied to a series of side channel measurements of a microcontroller AES implementation and simulations. A comparison to related work shows that the new algorithm improves on existing algorithms in several respects.
The association between functional impairment pre- and post-cystectomy with neoadjuvant chemotherapy use in patients with muscle-invasive bladder cancer.

e17008Background: Standard of care treatment for muscle-invasive bladder cancer (MIBC) includes neoadjuvant chemotherapy (NAC) followed by radical cystectomy (RC), which can be associated with majo...
E-119 Surpass streamline flow diverter use in treating cervical carotid pseudoaneurysms: a case series

Introduction Flow diverter stents have revolutionized endovascular treatment for cerebral aneurysms not amenable to coil embolization. Originally, the Pipeline embolization device (PED) emerged as a novel system for treating large/giant, or wide-necked intracranial carotid artery (ICA) aneurysms from the petrous to superior hypophyseal segments, with later extension up to the terminus with small/medium aneurysms. Recently, the Surpass streamline flow-diverter (SSFD) has shown promise for diversifying flow-diversion options for aneurysm treatment. The SSFD differs from PED by increasing pore density while maintaining high metal-surface-area to ensure uniform flow disruption between the parent artery and aneurysmal lumen. The SSFD also expands from 5 mm up to 7 mm further diversifying treatment possibilities. There are few reports of flow-diverter stents used for cervical carotid pseudoaneurysms in the literature. However, the SSFD appears uniquely well adapted to targeting these aneurysms given the system’s increased diameter/length options and expandability. Here, we describe our group’s experience with the SSFD as a stand-alone flow-diversion solution for cervical carotid pseudoaneurysms. Materials and Methods Data pertaining to cervical pseudoaneurysms treated with SSFD were gathered retrospectively January 2019 to now. Data included age, aneurysm type (sidewall, fusiform), size, symptoms, number of stents placed, and SSFD dimensions. Indications for stent placement included enlarging aneurysm, worsening compressive symptoms, and TIA/stroke. Complications were noted at four time points post-operatively: Results Three patients underwent SSFD placement for cervical carotid pseudoaneurysms. Ages ranged from 55–78. Two patients had symptomatic sidewall aneurysms measuring 1.7 × 2.1 cm and 1.8 × 1.3 cm. Both patients developed vocal hoarseness. One patient experienced vasovagal episodes while the other experienced TIAs. Another patient had an incidentally discovered fusiform aneurysm measuring 1.3 × 1.5 cm. There were no complications at any time point. One to three stents were deployed intra-operatively. Post-procedural SMART grade was 0 for two patients, and 2 for the third patient. One-year angiogram demonstrated SMART grade 3 occlusion with a minimally visualized neck remnant for one patient without parent artery stenosis. Six month MRI/MRA demonstrated total occlusion in another patient. Follow-up data was not available from the last patient as their initial intervention occurred Conclusions SSFD successfully treated three patients with cervical carotid pseudoaneurysms at our institution from 2019 to present with no complications, satisfactory angiographic appearance, and symptom resolution. Though further research is required to confirm these results, we demonstrate that SSFD appears both safe and effective for endovascular treatment of cervical carotid pseudoaneurysms. Disclosures R. Achey: None. L. Sheikhi: None. T. Patterson: None. G. Toth: None. N. Zobenica Moore: None. M. Bain: None.
A High-Power, Low-Noise, Ultraviolet Laser System for Trapped-Ion Quantum Computing

We demonstrate a high power, modular, bichromatic, ultraviolet laser system based on the Master Oscillator / Power Amplifier (MOPA) configuration for quantum computing with 171Yb+ ions. Low phase noise allows for high fidelity qubit operations.
A High-Temperature Model for GaN-HEMT Transistors and its Application to Resistive Mixer Design

This article presents a high temperature model for gallium nitride (GaN) high electron mobility transistor (HEMT) on silicon carbide (SiC). The proposed model for the channel resistance $\text {R}_{\text {ds}}$ is based on an empirical nonlinear model. The model is applied to design a resistive mixer of a high temperature transceiver for downhole communications through a systematic approach and estimate the performance of the mixer. The proposed model matches well with measurement results of the mixer and accurately estimates its performance at temperatures up to 250 °C. The model is also applied to obtain the optimal gate bias voltage of the mixer for a given temperature. The optimal bias voltage scheme reduces the conversion loss of the mixer by a factor of 8.4 dB at 250 °C under the local oscillator power of −10 dBm.
Get privacy trending: Best practices for the social media educator

Social media is an increasingly popular forum for medical education. Many educators, including those in infectious diseases, are now creating and sharing unique and educational patient cases online. Unfortunately, some educators unknowingly threaten patient privacy and open themselves to legal liability. Further, the use of published figures or tables creates risk of copyright infringement. As more and more infectious diseases physicians engage in social media, it is imperative to create best practices to protect both patients and physicians. This summary will define the legal requirements of patient de-identification as well as other practical recommendations as they relate to use of clinical case information, patient images, and attribution of primary references on social media.
Darmok and Jalad at Tanagra: A Dataset and Model for English-to-Tamarian Translation.

Tamarian, a fictional language introduced in the Star Trek episode Darmok, communicates meaning through utterances of metaphorical references, such as "Darmok and Jalad at Tanagra" instead of "We should work together." This work assembles a Tamarian-English dictionary of utterances from the original episode and several follow-on novels, and uses this to construct a parallel corpus of 456 English-Tamarian utterances. A machine translation system based on a large language model (T5) is trained using this parallel corpus, and is shown to produce an accuracy of 76% when translating from English to Tamarian on known utterances.
Laboratory Office Hours as Outreach in the Health Sciences: Better Research Skills for Better Careers.

Medical librarianship is changing in health care environments. Since 1996, by which time the standards that determine how hospitals acquire accreditation changed, many hospitals have been acquiring accreditation without a qualified medical librarian on site. For that reason, it has become even more important that health care professionals, doctors, nurses, and other clinicians learn to access and evaluate quality information as an integral part of their academic training. Medical clinicians now must begin their careers with strong research skills. These skills must be attained during their academic matriculation, and studies in the field of librarianship have shown that departmental outreach hours are an extremely effective way to promote library services to university students and faculty. Other methods, such as technology applications, are useful but have their limitations. This paper reviews current literature on the vital importance of in-person outreach to future health care professionals and illustr...
Honey sources: neural network approach to bee species classification

Abstract Bees are the main pollinators of the world and are dying at an alarming rate. Being able to classify them and study their habits is of paramount importance. Crowdsourced datasets are preferred methods for gathering data about the current state of bee populations in their natural environment. Such images, however, may be problematic to use due to large volume of images that place strain on the experts’ capabilities of identifying the species. We propose a method to identify regions of interest in an image containing a bee and to correctly classify the species of the bee. In addition, the procedure works on large crowdsourced datasets (we worked with BeeSpotter) with minimal manual annotation and data augmentation. Our approach is capable of addressing two genus and related bee species and records 91% correct classification. A limitation of the BeeSpotter dataset is labeling just one bee per image which may contain two or more bees. We overcome this issue by classifying all bees even in cases of two genus. Finally, the proposed approach is compared with two other recent works which report similar accuracy, but are limited with stricter image preprocessing or photographic setup.
Computational homogenization of the debonding of particle reinforced composites: The role of interphases in interfaces

Abstract There are four primary factors which influence the macroscopic constitutive response of particle reinforced composites: component properties, component concentrations, interphases, and interfacial debonding. Interphases are often a byproduct of surface treatments applied to the particles to control agglomeration. Alternatively, in polymer based materials such as carbon-black reinforced rubber, an interphase or “bound rubber” phase often occurs at the particle–matrix interface. This interphasial region has been known to exist for many decades, but is often omitted in computational investigations of such composites. In this paper, we present an investigation into the influence of interphases on the large deformation response of particle reinforced composites. In addition, since particles tend to debond from the matrix at large deformations, we investigate the influence of interfacial debonding on the macroscopic constitutive response. The investigation considers two different microstructures; both a simplified single particle model, and a more complex polydisperse representative unit cell. Cohesive elements, which follow the Park–Paulino–Roesler traction–separation relation, are inserted between each particle and its corresponding interphase to account for debonding. To account for friction, we present a new, coupled cohesive–friction model and detail its formulation and implementation. For each microstructure, we discuss the influence of the interphase thickness and stiffness on the global constitutive response in both uniaxial tension and simple shear. To validate the computational framework, comparisons are made with experimental results available in the literature.
Interior and Boundary Stabilization of Navier-Stokes Equations

We report on very recent work on the stabilization of the steady-state solutions to Navier-Stokes equations on an open bounded domain Ω ⊂ R d, d = 2, 3, by either interior, or else boundary control.
Phrasal equivalence classes for generalized corpus-based machine translation

Generalizations of sentence-pairs in Example-based Machine Translation (EBMT) have been shown to increase coverage and translation quality in the past. These template-based approaches (G-EBMT) find common patterns in the bilingual corpus to generate generalized templates. In the past, patterns in the corpus were found by only few of the following ways: finding similar or dissimilar portions of text in groups of sentence-pairs, finding semantically similar words, or use dictionaries and parsers to find syntactic correspondences. This paper combines all the three aspects for generating templates. In this paper, the boundaries for aligning and extracting members (phrase-pairs) for clustering are found using chunkers (hence, syntactic information) trained independently on the two languages under consideration. Then semantically related phrase-pairs are grouped based on the contexts in which they appear. Templates are then constructed by replacing these clustered phrase-pairs by their class labels.We also perform a filtration step by simulating human labelers to obtain only those phrase-pairs that have high correspondences between the source and the target phrases that make up the phrase-pairs. Templates with English-Chinese and English-French language pairs gave significant improvements over a baseline with no templates.
Simulation of hydrocarbon diffusion in zeolites

Simulation of hydrocarbon diffusion in zeolites provides insights into the effects of diffusant molecular weight and structure, and the physical processes controlling diffusion. Different approaches for simulating hydrocarbon diffusion are considered and the results are compared with experiment.
Abstract 19799: The Addition of Galectin-3 Significantly Improves Upon the Ability of Discharge BNP to Predict 60 Day Readmission for Acute Decompensated Heart Failure

Introduction: Acute decompensated heart failure (ADHF) is a major reason for repeated hospitalizations. Identifying those patients with HF at risk for readmission is critical so that preventative interventions can be implemented. Biomarkers such as BNP and galectin-3 (Gal-3) assessed at discharge may potentially be useful, though their role in predicting short-term readmission is not well defined in literature. Methods: We enrolled and had follow up data for 91 participants admitted to our facility between 4/2013 and 1/2014 with a primary diagnosis of ADHF. Gal-3 and BNP were obtained within 48 hours prior to hospital discharge after management for ADHF. Gal-3 was assessed using a commercially available assay. We compared subjects who were and were not readmitted (re-ad). Results: Discharge BNP was found to be a significant predictor of 30 and 60 day readmission [AUC 0.69 (p=0.046), AUC 0.7 (p=0.005) respectively]. The addition of Gal-3 to discharge BNP provided significantly improved prediction of 60 day re-admission. The net reclassification improvement (NRI) was 55.2% (p=0.037). 14% of re-admitted participants were correctly reclassified and 41% of non-readmitted patients were correctly reclassified using this approach. A statistically significant NRI was not found upon examination of 30 day readmission. Conclusions: Measurement of both Gal-3 and BNP at hospital discharge provides significant prediction of hospital re-admission within 60 days. When combined, the prediction of re-admission is significantly improved. This data will be useful to help identify those at-risk of re-admission and aid in efficiently implementing appropriate interventions to reduce re-admission rates.
Neonatal hypertension associated with renal artery hypoplasia.

A newborn infant was presented with severe hypertension, associated with congenital hypoplasia See Images in the PDF file of the abdominal aorta and bilateral renal hypoplasia.
Preliminary Observations on the Rapid Differentiation of the Klebsiella-Enterobacter-Serratia Group on Bile-Esculin-Agar

A total of 232 isolates of Enterobacteriaceae and 19 Pseudomonas species were tested on bile-esculin-agar. Only the Klebsiella-Enterobacter-Serratia group produced blackening of the medium.
Local Training for Radial Basis Function Networks: Towards Solving the Hidden Unit Problem

This work examines training methods for radial basis function networks (RBFNs). First, the theoretical and practical motivation for RBFNs is reviewed, as are two currently popular training methods. Next a new training method is developed using well known results from functional analysis. This method trains each kidden unit individually, and is thus called the local training method. The structure of the method allows analysis of individual hidden units; moreover a covariance-related quantity is defined that gives insight into how many hidden units to employ. Two examples illustrate the usefulness of the method. Lastly, an ad hoc method to further improve RBFN performance is demonstrated.
Pancreatic enzyme mechanisms that trigger physiological shock and high mortality

Non-infectious inflammation is encountered in many human diseases. One of the strongest forms of inflammations occurs in physiological shock, a condition with high levels of cardiovascular cell activation, failure in the function of multiple organs and high mortality. We previously reported that pancreatic digestive proteases might be generating inflammatory peptides from proteins, in part extra-cellular matrix proteins, located in the wall of the intestine. To identify which particular pancreatic enzymes may be triggering the production of inflammatory activators in shock, the pancreatic serine proteases trypsin, chymotrypsin, and elastase were reacted with supernatants of homogenized intestines and hearts from Wistar rats and tested for their ability to activate neutrophils, a non-specific immune cell type involved in acute inflammation. All three proteases served to generate neutrophil activators from the intestine and the heart. Moreover, we found that elastase reacted with heart supernatant produced a level of inflammatory stimulation that caused not only cell activation but also direct neutrophil necrosis. We conclude that pancreatic serine proteases may represent key players during the rapid organ failure encountered in shock.
On making engineering sexy

The author examines ways in which engineering educators can improve the current public image of the engineering profession. His recommendations include: engineers making themselves understood; focusing on engineering wonders; collecting examples of "heroic" engineering; making engineering work into a game; using inclusive language; and spreading information in nontraditional ways.
Excitation modeling in a homomorphic vocoder

An efficient dynamic excitation modeling which emphasizes either the pitch-dependent periodic nature or the more random nature of the sound sources depending on the voicing state of the speech signal is applied to the homorphic vocoder. In this excitation modeling scheme, the cepstral peak value is used as the basis for classifying a given speech segment into three different classes: voiced, unvoiced, and mixed. Different excitation modeling strategies are used for the different classes. The algorithm is simulated, and clear improvement in the speech quality is shown. >
PHOTODYNAMIC BIOASSAY OF BENZO(A)PYRENE WITH PARAMECIUM CAUDATUM.

The photodynamic toxicity of benzo(a)pyrene (BaP) to Paramecium caudatum and a variety of other in vivo systems is well established. Recent improvements in the culture of P. caudatum have facilitated standardization of the photodynamic response. A simple bioassay procedure, based on this response, was developed as a preliminary to the assay for photodynamic toxicity of crude organic extracts, such as atmospheric pollutants.
Motivational Interviewing and Skills-Based Counseling for Sustained Reduction in Saturated Fat Intake

Abstract Guidelines for health recommend restricting the consumption of saturated fat. Motivating clients to sustain this type of lifestyle is challenging. This 24-week study was designed to assess the impact of motivational interviewing (MI) and skills-based counseling (SBC) on the lifestyles of cardiac patients. Saturated fat intake (% of total calories) was determined from 3-day food records. Two 60-minute MI sessions (weeks 1 & 13) and three 30-min SBC sessions (weeks 2, 3 & 7) added to a traditional (TR) 12-week rehabilitation program comprised the experimental treatment (ET); TR=control treatment (CT). Sixty patients with coronary artery disease were assigned at random to ET (n=28) or CT (n=32). ANCOVA was performed at both 12 and 24 weeks. At 12 weeks ET resulted in a significantly (p=0.047) greater reduction in saturated fat consumption than the CT. At 24 weeks ET patients had reduced their intake of saturated fat from 5.8% at baseline to 4.9%. The CT patients had changed from 7.1% to 7.2%. Hie difference between groups remained significant (p=0.014) from baseline to 24 weeks, ft was concluded that adding MI and SBC to a traditional early outpatient cardiac rehabilitation program significantly improves saturated fat consumption for at least 6 months.