cssi/SciSciGPT-SciSciNet huggingface dataset:
21 years. 21 Stories. Creating a Community of Giving at the IUPUI University Library

This article describes goals and strategies for a library communications and fundraising program designed to mark a milestone anniversary. The authors report on a targeted public relations effort to enhance fundraising results and review development outcomes in the context of current literature related to donor loyalty and fundraising for libraries. Particular emphasis is placed on the value of creating compelling stories about the individuals who shape the life of the library and its ability to impact the wider community, especially donors whose gifts facilitate unique programs and collections. This approach aligns with considerations identified in both fundraising and library literature, which underscore the effectiveness of utilizing story to deepen connections with and motivate donors.
Communication-Based Assessment of Developmental Age for Young Children With Developmental Disabilities

Purpose In this study, the authors compared a multiple-domain strategy for assessing developmental age of young children with developmental disabilities who were at risk for long-term reliance on a...
3D Integral Imaging Reconstruction of Occluded Objects Using Independent Component Analysis-Based K-Means Clustering

We explore algorithms of independent component analysis and K-means applied to 3D reconstruction of occluded objects using integral imaging. 3D reconstruction of occluded objects is implemented using the elemental images of the separated objects from occlusion. Experimental and theoretical results are presented. We show that the 3D reconstructed images using the proposed method may perform better than those using the conventional method in terms of contrast, sharpness and average normalized rms error (RMSE) metrics.
Boundary Current Eddies and Their Role in the Restratification of the Labrador Sea

An idealized model is used to study the restratification of the Labrador Sea after deep convection, with emphasis on the role of boundary current eddies shed near the west coast of Greenland. The boundary current eddies carry warm, buoyant Irminger Current water into the Labrador Sea interior. For a realistic end-of-winter state, it is shown that these Irminger Current eddies are efficient in restratifying the convected water mass in the interior of the Labrador Sea. In addition, it is demonstrated that Irminger Current eddies can balance a significant portion of the atmospheric heat loss and thus play an important role for the watermass transformation in the Labrador Sea.
Nitrogen deposition to lakes in national parks of the western Great Lakes region: Isotopic signatures, watershed retention, and algal shifts

Atmospheric deposition is a primary source of reactive nitrogen (Nr) to undisturbed watersheds of the Great Lakes region of the U.S., raising concerns over whether enhanced delivery over recent decades has affected lake ecosystems. The National Atmospheric Deposition Program (NADP) has been measuring Nr deposition in this region for over 35 years. Here we explore the relationships among NADP-measured Nr deposition, nitrogen stable isotopes (δ15N) in lake sediments, and the response of algal communities in 28 lakes situated in national parks of the western Great Lakes region of the U.S. We find that 36% of the lakes preserve a sediment δ15N record that is statistically correlated with some form of Nr deposition (total dissolved inorganic N, nitrate, or ammonium). Furthermore, measured long-term (since 1982) nitrogen biogeochemistry and inferred critical nitrogen loads suggest that watershed nitrogen retention and climate strongly affect whether sediment δ15N is related to Nr deposition in lake sediment records. Measurements of algal change over the last ~ 150 years suggest that Nr deposition, in-lake nutrient cycling, and watershed inputs are important factors affecting diatom community composition, in addition to direct climatic effects on lake physical limnology. The findings suggest that bulk sediment δ15N does reflect Nr deposition in some instances. In addition, this study highlights the interactive effects of Nr deposition and climate variability.
Granulocyte colony-stimulating factor promotes adhesion of neutrophils

Granulocyte colony stimulating factor (G-CSF) is well known for its ability to drive the maturation and mobilization of neutrophils. G-CSF also appears to have the potential to activate functions of mature neutrophils, influencing recruitment at sites of inflammation and tissue injury. We investigated the ability of G-CSF to stimulate adhesion of isolated blood neutrophils. G-CSF induced significant adherence to intercellular adhesion molecule (ICAM)-1 that was both macrophage antigen-1 (Mac-1) and leukocyte function-associated antigen-1 dependent. The kinetics of G-CSF-stimulated adhesion to ICAM-1 peaked at 11 min without detectable surface upregulation of Mac-1. This was in marked contrast to chemokines, in which peak activation of adhesion is seen within 1 min of stimulation. In contrast to chemokine-induced adhesion, G-CSF stimulation was not inhibited by pertussis toxin. G-CSF also augmented the attachment of neutrophils to activated human umbilical vein endothelial cells (HUVEC) through specific effects on neutrophils, because HUVEC appear to lack functional G-CSF receptors.
Immobilization of azurin with retention of its native electrochemical properties at alkylsilane self-assembled monolayer modified indium tin oxide

Abstract Indium tin oxide (ITO) is a promising material for developing spectroelectrochemical methods due to its combination of excellent transparency in the visible region and high conductivity over a broad range of potential. However, relatively few examples of immobilization of redox proteins at ITO with retention of the ability to transfer electrons with the underlying material with native characteristics have been reported. In this work, we utilize an alkylsilane functionalized ITO surface as a biocompatible interface for immobilization of the blue copper protein azurin. Adsorption of azurin at ITO as well as ITO coated with self-assembled monolayers of (3-mercaptopropyl)trimethoxysilane (MPTMS) and n-decyltrimethoxysilane (DTMS) was achieved, and immobilized protein probed using protein film electrochemistry. The native redox properties of the protein were perturbed by adsorption directly to ITO or to the MPTMS layer on an ITO surface. However, azurin adsorbed at a DTMS covered ITO surface retained native electrochemical properties ( E 1/2 = 122 ± 5 mV vs. Ag/AgCl) and could exchange electrons directly with the underlying ITO layer without need for an intervening chemical mediator. These results open new opportunities for immobilizing functional redox proteins at ITO and developing spectroelectrochemical methods for investigating them.
Thyrotropin-releasing hormone receptor occupancy determines the fraction of the responsive pool of inositol lipids hydrolysed in rat pituitary tumour cells

We report that there are distinct thyrotropin-releasing hormone (TRH)-responsive and -unresponsive pools of inositol (Ins) lipids in rat pituitary tumour (GH3) cells, and present evidence that the size of the responsive pool is determined by the number of activated TRH-receptor complexes. By use of an experimental protocol in which cycling of [3H]Ins is inhibited and resynthesis occurs with unlabelled Ins only, we were able to measure specifically the effects of TRH on the hydrolysis of the Ins lipids present before stimulation. A maximally effective dose of TRH (1 microM) caused a time-dependent decrease in 3H-labelled Ins lipids that attained a steady-state value of 42 +/- 1% of the initial level between 1.5 and 2 h. After 2 h, even though there was no further decrease in 3H-labelled Ins lipids, and no increase in [3H]Ins or [3H]Ins phosphates, turnover of Ins lipids, as assessed as incorporation of [32P]Pi into PtdIns, continued at a rate similar to that in cells incubated without LiCl or unlabelled Ins. These data indicate that Ins lipid turnover was not desensitized during prolonged TRH stimulation. Depletion of lipid 3H radioactivity by TRH occurred at higher TRH doses on addition of the competitive antagonist chlordiazepoxide. Addition of 1 microM-TRH after 3 h of stimulation by a sub-maximal (0.3 nM) TRH dose caused a further decrease in 3H radioactivity to the minimum level (40% of initial value). We propose that the TRH-responsive pool of Ins lipids in GH3 cells is composed of the complement of Ins lipids that are within functional proximity of activated TRH-receptor complexes.
PEDOT:PSS/QCM-based multimodal humidity and pressure sensor

Abstract A room temperature multimodal sensor composed of poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) deposited on an AT-cut quartz crystal microbalance (QCM) crystal was fabricated. The sensor’s nonlinear motional resistance and frequency responses are deconvoluted using a feedforward backpropagation neural network (FBN), which allows a single sensor to function simultaneously as a relative humidity (RH) sensor and a pressure sensor using only two electrodes. We demonstrate that the predictive ability of the sensor is highly influenced by the data used to train the FBN. When training sets are tailored to resemble the operating conditions of the sensor, the sensor achieves an average resolution of
Publication patterns of presentations at the Society of Teachers of Family Medicine and North American Primary Care Research Group annual meetings.

BACKGROUND AND OBJECTIVES The annual meetings of the Society of Teachers of Family Medicine (STFM) and the North American Primary Care Research Group (NAPCRG) are important peer-reviewed venues for family medicine academicians to present their research. However, a relatively small number of individuals actually hear each presentation. In order to permanently share their research with a large number of peers, these presenters need to take the next step and publish completed manuscripts. This study examined the frequency with which presentations at these meetings are eventually published. METHODS All abstracts from the 1987 and 1988 meetings of NAPCRG and the PEER and research sections of STFM were followed by performing a Medline computer search for the presenting author. Publications that matched the presentations were identified, and information was recorded about the elapsed time between presentation and publication, and the journal where publication occurred. RESULTS Just under half (48%) of all the presentations were published within 4 or 5 years. There was no difference between 1987 and 1988 presentations, nor between NAPCRG and the combined STFM presentations. However, 69% of STFM research presentations were published compared to 31% of the peer presentations (X2 = 20.6, df = 2, P < .001). The STFM research publications also tended to be in print sooner than other presentations. Fifty-six percent of the publications occurred in family practice journals, with Family Medicine and the Journal of Family Practice being the most common journals. CONCLUSIONS Approximately half of the presentations at STFM and NAPCRG annual meeting are published within 4 to 5 years. This is consistent with publication rates found for other specialty meetings. The reasons for not publishing are numerous and need to be better elucidated to help family medicine academicians complete the research loop and disseminate their findings to the scientific community.
Breast Cancer in Pregnant and Postpartum Women

Abstract Breast cancer is reported to occur in from I in 3000 to I in 10 000 pregnancies worldwide. In the United States, 10% to 20% of breast cancers occur in women of childbearing age. Diagnosis and treatment of breast cancer during pregnancy present many additional challenges.
Biologic Augmentation of Rotator Cuff Repair

In this chapter current strategies of biological augmentation of rotator cuff repair are summarized and discussed. The chapter begins by explaining the regulatory standards for biological augmentation methods, followed by a discussion of commonly used preclinical animal models for evaluating rotator cuff repair.
Similar sleep EEG topography in middle-aged depressed patients and healthy controls.

Objectives: One of the early hypotheses relating sleep disturbances in depression to a model of sleep regulation is the S-deficiency hypothesis. It is postulated that, in depressed patients, sleep propensity during wakefulness does not rise to the level attained by nondepressed subjects, resulting in altered sleep structure or changes in the electroencephalogram during sleep. We aimed to test this hypothesis by assessing topographic changes in the sleep electroencephalogram associated with depression. Design: Cross-sectional clinical study. Setting: Mental Health Clinical Research Center. Participants: Sixteen unmedicated depressed outpatients (mean age: 41.2 years) and 16 pair-matched healthy controls (mean age: 41.1 years). Interventions: None. Measurements: Baseline sleep electroencephalogram recordings were obtained from a central referential electrode and from 3 bipolar derivations (frontocentral, centroparietal, parietooccipital) along the anteroposterior axis. Results: Symptoms of depression at the time of sleep recordings were moderate (24-item Hamilton Rating Scale of Depression range: 16-31). No differences between patients and controls were found in sleep variables and all-night electroencephalogram spectra in non-rapid-eye-movement and rapid-eye-movement sleep. The ultradian modulation of slow-wave activity (power within 0.75-4.5 Hz), as well as the exponential decline of slow-wave activity, during sleep did not differ between the groups. The statistical analyses of electroencephalogram power gradients between adjacent derivations revealed no Group × Derivation interactions. An anterior dominance in non-rapid-eye-movement sleep power was present in the 0.75- to 2-Hz range, which diminished throughout the night. Conclusions: These findings in moderately depressed patients do not support the existence of an S-deficiency during sleep. Because the build up of sleep propensity during waking can be dissociated from its decline, future studies need to investigate the waking electroencephalogram spectra in depression.
Blood substitutes for transfusion

Faced with an increased demand for blood products and a stable donor pool, different companies have developed products for oxygen carrying from hemoglobin, to fluorocarbon based compounds (the latter based on Teflon like products). There are several difficulties in showing efficacy of these compounds, and the reasons are discussed. In addition, various strategies for production of oxygen-carrying blood substitutes (OCBS) are noted as well as other applications for these compounds.
An Analysis of Criteria Associated with Developing Hospital Image

Nonprofit organizations are increasingly discovering modern principles of marketing. Constrained by a limited service area, changing medical technology and growing competition, community hospitals find it desirable to apply marketing research in order to assess potential, identify user needs and to utilize the information generated for designing a program to improve their image. Based upon a study completed for a Midwestern community hospital, this paper attempts to identify the important criteria essential for developing a favorable image for a hospital.
In Practice: Perceptions of User Involvement in the Activewear Industry

Within the field of functional apparel design, DeJonge (1981) explains that users are relied upon to clarify problems, pinpoint critical design considerations, and provide insight on their expectations. These methods are used to help the designer move beyond the apparent request of the client toward a more comprehensive picture of the problem (DeJonge, 1984). The literature is focused on how users are engaged in practice but does not address designer’s attitudes in engaging users or the value of user involvement in the apparel product development process. This research explores these issues through industry interviews with apparel designers and developers who elaborate on their perception of the value of user involvement.
Not All Transformational Leadership Behaviors Are Equal: The Impact of Followers’ Identification With Leader and Modernity on Taking Charge:

This study investigates how each dimension of transformational leadership directly and indirectly influences followers’ change-oriented behaviors. Using a sample of 329 independent leader–follower dyads from a wide range of Chinese organizations, we examine followers’ identification with leader as an intervening variable between the four dimensions of transformational leadership (“core” transformational behaviors, high-performance expectations, individualized support, and intellectual stimulation) and followers’ taking charge behaviors. Results showed that intellectual stimulation had the highest relative effect size that was largely due to its direct effect on taking charge. Individualized support only exerted a significant indirect effect. Additionally, the negative direct and positive indirect effects of high-performance expectations rendered its total effect nonsignificant. Furthermore, the direct, indirect, and total effects of “core” transformational behaviors were nonsignificant. We also found that...
Open and Endovascular Abdominal Aortic Injury Repair Outcomes in Polytrauma Patients.

Introduction The management of patients with abdominal aortic injury (AAI) remains challenging. Open repair of AAI is still the standard of care although it is associated with high mortality. In past few years, endovascular surgery has evolved as a less invasive alternative to open surgery in emergency settings. The objective of this study was to compare outcomes after open repair versus endovascular repair of AAI in polytrauma patients. Methods The National Trauma Data Bank, from 2008 to 2012, was queried to identify trauma patients undergoing open and endovascular repair of AAI using International Classification of Diseases, ninth Edition, and Clinical Modification codes. Data reviewed included demographics, type of associated injury, type of operative management, and complications. Factors independently associated with mortality were evaluated using multivariate logistic regression model. Results Of 325 injured patients with AAI, 91 patients underwent endovascular repair and 234 patients underwent open repair. Of these, 80.6% were male, with a mean age of 35.70 years, and a mean injury severity score (ISS) was 30.59 for patients undergoing open repair and 31.56 for endovascular repair. Associated traumatic injuries included bowel injuries 57.5%, liver-pancreas injuries 36.6%, splenic injuries 14.8%, renal injuries 15.7%, and retroperitoneal injuries 19.1%. In-patient mortality for patients undergoing the open repair cohort was 63.7% and 20.9% for patients in the endovascular cohort (P Conclusions Endovascular repair of abdominal aorta in polytrauma patients seems to be feasible and may improve survivorship in appropriately selected patients. More research is needed to understand to identify indications for endovascular repair versus open repair.
High temperature transducer using aluminum nitride single crystal for laser ultrasound detection

In this work, a new ultrasound nondestructive testing (NDT) method based on laser-generated Lamb wave detection was proposed for high temperature (HT) NDT. Lamb waves were introduced to a stainless steel plate by the Nd:YAG pulsed laser at one point and detected by aluminum nitride (AlN) transducer at a distant position. The fundamental symmetric (S 0 ) and antisymmetric (A 0 ) mode Lamb waves were successfully propagated in the thin stainless steel plate. The time-of- flight (TOF) of the S 0 and A 0 mode waves proportionally increased with the distance (D) between the laser source and the sensor, and almost no attenuation of the amplitude was observed. For the HT NDT experiment, AlN single crystal was adopted as the ultrasonic sensor material due to its high thermal resistance of the dielectric and piezoelectric constants at the elevated temperature up to 800 °C. The combination of non-contact, portable laser source as a Lamb wave generator and temperature-robust NDT sensor made of AIN has shown its great capability to detect the Lamb waves at elevated temperatures.
Epileptogenesis meets Occam's Razor

Pharmacological treatment to prevent brain injury-induced temporal lobe epileptogenesis has been generally unsuccessful, raising the issues of exactly when the conversion process to an epileptic brain state occurs and reaches completion, and which cellular or network processes might be the most promising therapeutic targets. The time course of epileptogenesis is a central issue, with recent results suggesting that injury-induced epileptogenesis can be a much more rapid process than previously thought, and may be inconsistent with a delayed epileptogenic mechanism. Simplification of the seemingly complex issues involved in the use of epilepsy animal models might lead to a better understanding of the nature of injury-induced epileptogenesis, the significance of the 'latent' period, and whether current strategies should focus on preventing or modifying epilepsy.
Student internalizing and externalizing behavior screeners: evidence for reliability, validity, and usability in elementary schools

Universal screening for emotional and behavioral risk in schools facilitates early identification and intervention for students as part of multitiered systems of support. Early identification has the potential to mitigate adverse outcomes of emotional and behavioral disorders. The purpose of this study was to extend existing research on the technical adequacy and usability of two universal screening measures, the Student Internalizing Behavior Screener (SIBS) and the Student Externalizing Behavior Screener (SEBS). Findings provided evidence for the reliability, concurrent validity, short-term predictive validity, and usability of the SIBS and SEBS in a sample of 154 elementary school students and their teachers. As a secondary focus, the technical adequacy and usability of the SIBS and SEBS was compared with that of two well-researched universal behavioral screening measures (Behavioral and Emotional Screening System and Social Skills Improvement System–Performance Screening Guide). Results indicated that...
Robust Energy Minimization for BRDF-Invariant Shape from Light Fields

Highly effective optimization frameworks have been developed for traditional multiview stereo relying on lambertian photoconsistency. However, they do not account for complex material properties. On the other hand, recent works have explored PDE invariants for shape recovery with complex BRDFs, but they have not been incorporated into robust numerical optimization frameworks. We present a variational energy minimization framework for robust recovery of shape in multiview stereo with complex, unknown BRDFs. While our formulation is general, we demonstrate its efficacy on shape recovery using a single light field image, where the microlens array may be considered as a realization of a purely translational multiview stereo setup. Our formulation automatically balances contributions from texture gradients, traditional Lambertian photoconsistency, an appropriate BRDF-invariant PDE and a smoothness prior. Unlike prior works, our energy function inherently handles spatially-varying BRDFs and albedos. Extensive experiments with synthetic and real data show that our optimization framework consistently achieves errors lower than Lambertian baselines and further, is more robust than prior BRDF-invariant reconstruction methods.
Selective Serotonin Reuptake Inhibitors

Selective serotonin reuptake inhibitors (SSRIs) are used primarily for treatment of depression and anxiety. Their effectiveness in pain management is limited and inconsistent.
Evaluating semantic relations in neural word embeddings with biomedical and general domain knowledge bases

In the past few years, neural word embeddings have been widely used in text mining. However, the vector representations of word embeddings mostly act as a black box in downstream applications using them, thereby limiting their interpretability. Even though word embeddings are able to capture semantic regularities in free text documents, it is not clear how different kinds of semantic relations are represented by word embeddings and how semantically-related terms can be retrieved from word embeddings. To improve the transparency of word embeddings and the interpretability of the applications using them, in this study, we propose a novel approach for evaluating the semantic relations in word embeddings using external knowledge bases: Wikipedia, WordNet and Unified Medical Language System (UMLS). We trained multiple word embeddings using health-related articles in Wikipedia and then evaluated their performance in the analogy and semantic relation term retrieval tasks. We also assessed if the evaluation results depend on the domain of the textual corpora by comparing the embeddings of health-related Wikipedia articles with those of general Wikipedia articles. Regarding the retrieval of semantic relations, we were able to retrieve semanti. Meanwhile, the two popular word embedding approaches, Word2vec and GloVe, obtained comparable results on both the analogy retrieval task and the semantic relation retrieval task, while dependency-based word embeddings had much worse performance in both tasks. We also found that the word embeddings trained with health-related Wikipedia articles obtained better performance in the health-related relation retrieval tasks than those trained with general Wikipedia articles. It is evident from this study that word embeddings can group terms with diverse semantic relations together. The domain of the training corpus does have impact on the semantic relations represented by word embeddings. We thus recommend using domain-specific corpus to train word embeddings for domain-specific text mining tasks.
University Outdoor Recreation Program Participation: Comparing Benefits, Constraints, and Willingness to Pay Between Males and Females

This study examined and compared differences between gender groups regarding benefits, constraints, and willingness to pay related to university outdoor recreation programs. This information furthers understanding of these demographic groups and could assist decision makers with developing, marketing, and funding outdoor recreation programs targeted at higher education groups. Researchers crafted five hypotheses: Hypothesis 1: Females will participate in outdoor recreation less frequently than males will. Hypothesis 2: Females will rate benefits for participating in outdoor recreation higher than males will. Hypothesis 3: Females will rate constraints to participating in outdoor recreation higher than males will. Hypothesis 4: Females will rate the importance of outdoor programs higher than males will. Hypothesis 5: Female respondents will be willing to pay less for university programs than males will. Subscribe to JOREL
Reforming sacred institutions, part II: the Soviet Party-State and the Roman Catholic Church compared

The Soviet Party-State and the Roman Catholic Church are conceptualized as hierocratic institutions that faced analogous challenges of adaptation to a changing world from the 1950s onward. Building...
Rev. of Autobiographical Writing in Latin America: Folds of the Self

In Autobiographical Writing in Latin America: Folds of the Self, Sergio Franco maps a history of Spanish American autobiographical narratives—specifically, autobiography, memoir, and diary—and the ...
Anesthetic Management for Paraesophageal Hernia Repair

Paraesophageal hernia repairs are complex surgical cases frequently performed on patients of advanced age with multiple comorbidities, both of which create difficulties in the anesthetic management. Preoperative evaluation is challenging because of overlapping cardiopulmonary symptoms. The patient's symptoms and anatomy lead to an increased aspiration risk and the potential need for a rapid sequence induction. Depending on the surgical approach, lung isolation may be required. Communication with the surgeon is vital throughout the case, especially when placing gastric tube and bougies. Multimodal analgesia should include regional and/or neuraxial techniques, in addition to the standard intravenous and oral pain medications.
Fast Neighbor Discovery in MEMS FSO Networks

We investigate whether it is possible to achieve sub-millisecond latency for the discovery of multiple neighbors in laser-based Free Space Optical (FSO) networks. Given a large programmable array of micromirrors, we propose the use of adaptive boolean combinatorial group testing algorithms that are practical and efficient. The time taken scales as O(N log(L/N)) for N neighbors even if N is unknown, but no additional computation (e.g., matrix inversion) is required. Compared to Raster and Lissajous pattern-based scanning, we report 99.92% and 87% reduction in latency, respectively, for an array of 106 micromirrors (approximately XGA resolution). We conclude that it is indeed possible to achieve sub-ms latency given realistic network parameters. Our proposed algorithms are evaluated in simulation, and are compared against state of art neighbor discovery schemes.
Examining gendered variations in the internationalisation of businesses

The objective of this paper is to examine gendered variations in the internationalisation of businesses utilising the gender-aware framework. Using Global Entrepreneurship Monitor data, we examined our hypotheses across 70 countries. We found no gender differences in the internationalisation of businesses owned by entrepreneurs who were between the ages of 18-29. We also discovered that gender differences only exist in a few countries and in certain specific industries. This research contributes to women entrepreneurship literature by revealing the circumstances in which female-owned businesses internationalise to the same extent or even at a higher level than male-owned businesses.
Rare-earth element extraction from geothermal brine using magnetic core-shell nanoparticles-techno-economic analysis

Abstract Rare earth elements (REEs) are critical materials having a wide variety of applications such as generating and storing renewable energy. Extracting rare earth metals from geothermal brines is a very challenging problem due to the low concentrations of these elements and engineering challenges with traditional chemical separations methods involving packed sorbent beds or membranes that would impede large volumetric flow rates of geothermal fluids passing through a geothermal power plant. We demonstrate a simple and highly cost-effective nanofluid-based method for extracting rare earth metals from geothermal brines. Core-shell composite nanoparticles that contain a magnetic iron oxide core surrounded by a shell made of metal-organic framework (MOF) sorbent functionalized with chelating ligands were produced to selectively extract rare earth elements. A flowsheet model is used to estimate the capital and operating cost of a potential process to extract Eu from geothermal brines in the Salton Sea area using the magnetic nanofluid technology. The techno-economic analysis (TEA) results show that the annual productivity of Eu from the outlet brine stream of a typical 20 MW geothermal power plant is about 2151 kg. The capital cost to apply the PNNL magnetic nanofluid technology is about $6.8 M and the internal return rate (IRR) for this investment is about 18.1% based on the information collected for the year 2018. Sensitivity analysis has been carried out for some key parameters such as the REE concentration and price and adsorbent cost to reveal their impacts on the IRR.
A new method for determining optimal locations of bike stations to maximize coverage in a bike share system network

A new method that combines maximal covering location problem and bike station importance is utilized to find optimal locations of bike stations and maximize Bike Share System (BSS) demand coverage ...
Mjpt 16 Neoprene Pre Insulated Cable Sleeve /Electric Sleeves

At both laparoscopy and hysteroscopy, controlled movement of fluids is necessary. In addition, at laparoscopy, suctioning of accumulated smoke from lasers or electrosurgery is an essential venting technique to enhance visibility. This chapter will describe and discuss a unique, simple, cost-effective system that can be used for both hysteroscopy and laparoscopy to accomplish movement of fluids and management of smoke. Aquadissection or hydrodissection has been used for many years as an adjuvant to operative laparoscopy.' It has been found useful for operative laparoscopic treatment of conditions such as endometriosis, pelvic adhesions, and tubal obstructron. Most current systems are cumbersome, wastefully use large volumes of fluid, and often require a mechanical pump for pressurizing the fluid suction and irrigation systems. Usually, during combined laparoscopy and hysteroscopy, a separate system is used for accomplishing uterine distention when fluids are used for the hysteroscopic portion of surgery. The Pump Vac Plus can be used for both hysteroscopic distention and laparoscopic suction and irrigation. This article will describe our techniques for using the Pump Vac for both of these endoscopic approaches.
Sleep deprived but socially connected: balancing the risks and benefits of adolescent screen time during COVID-19

The COVID-19 pandemic has drastically altered the daily lives of families across the globe, forcing many to remain physically distanced and quarantine together at home as government-ordered shutdow...
Expanding the Spectrum of Chronic Immune Sensory Polyradiculopathy: CISP-Plus.

Objectives: Sensory loss with normal nerve conduction studies (NCS) from focal sensory root inflammatory demyelination is characteristic of chronic immune sensory polyradiculopathy (CISP). However, non-pure cases involving motor and distal sensory nerves exist (CISP-plus). We hypothesize that CISP-plus and CISP are fundamentally part of the same syndrome through comparison of clinical, neurophysiological and pathological features. Methods: CISP-plus (primary dorsal root with lesser motor and sensory nerve involvement) and CISP cases were retrospectively analyzed (1986-2019). Results: We identified 44 CISP-plus and 28 CISP cases (n=72) with 86% (38/44) of CISP-plus and 79% (22/28) of CISP patients experiencing imbalance. On examination, large fiber sensory loss was present in 98% (43/44) of CISP-plus and 96% (27/28) of CISP. Gait ataxia was evident in 93% (41/44) of CISP-plus and 79% (22/28) of CISP. Mild distal weakness was common in CISP-plus (75%, 33/44). NCS showed mild abnormalities in all CISP-plus and were normal (by definition) in all CISP. Elevated cerebral spinal fluid (CSF) protein, slowing of somatosensory evoked potentials and MRI root enhancement occurred in most CISP-plus and CISP cases. Eleven CISP-plus nerve biopsies showed loss of large myelinated fibers and onion-bulb formation most prominent in rootlet biopsies. Immunotherapy resulted in marked improvement of gait ataxia in 84% (27/32) of CISP-plus and 93% (14/15) of CISP cases with return to normal neurological examination in half (25/46). Conclusion: The recognition of CISP-plus expands the spectrum of CIDP by combining CISP-plus (predominant sensory polyradiculopathy with mild motor and sensory nerve involvement) with pure-CISP (focal sensory polyradiculopathy) together as proximal sensory CIDP.
Successful Coil Embolization Treatment of a Large Arterioportal Fistula: A Rare Cause of Mesenteric Ischemia.

Superior mesenteric arteriovenous fistulae (SMAVF) are a rare complication from trauma or iatrogenic surgical intervention. There are less than 50 cases reported in the literature and no clear guidelines as to the best practices for diagnosis and treatment. SMAVF are often asymptomatic but can present with nonspecific abdominal symptoms ranging from nausea and vomiting to gastrointestinal bleeding and mesenteric ischemia. Symptom onset, when present, is often delayed years after the inciting event, further complicating the diagnosis. We present a case of a 71-year-old man presenting with mesenteric ischemic symptoms secondary to a large SMAVF that was successfully treated with coil embolization. We describe our approach to treatment and describe the classical imaging findings. We, then, review the current literature and management recommendations.
"It's our mutual responsibility to share": The Evolution of Account Sharing in Romantic Couples

While most online accounts are designed assuming a single user, past work has found that romantic couples often share many accounts. Our study examines couples' account sharing behaviors as their relationships develop. We conducted 19 semi-structured interviews with people who are currently in romantic relationships to understand couples' account sharing behaviors over the lifecycle of their relationship. We find that account sharing behaviors progress through a relationship where major changes happen at the start of cohabitation, marriage, and occasional breakup. We also find that sharing behaviors and motivations are influenced by couples' relationship ecology, which consists of the dynamics between the couples and the social environment they live in. Based on these findings, we discuss implications for further study to support couples' sharing needs at different relationship stages and identify design opportunities for technology solutions to facilitate couples' sharing.
Getting stressed over topoisomerase I poisons.

Topoisomerase I is the target for a number of widely prescribed anticancer drugs that are based on camptothecin. In this issue of Cell Chemical Biology, Flor et al. (2020) demonstrate that the cellular response to camptothecin is mediated by lipid-derived electrophiles that are generated as a result of drug-induced oxidative stress.
Awareness for Atmospheres

In this essay I reflect on the meaning of atmospheres while the human world has been overwhelmed by a respiratory disease. In an auto-ethnographic gesture I reflect different ways of sensing and becoming sensitive to the atmospheric changes in my home during self-isolation. This self-questioning is directly related to the conceptualisation of air in view of its potential risk of carrying infectious virus particles. The air we breathe is currently stylised as a cloud on the micro level of aerosols, which gives reason to think anew about the status of the atmospheric with regard to our being in the world. Through combining philosophical reflection with aesthetic practice, I explore how an attunement towards the ways air flows through our habitats can open a new perspective on processes of subjectivation in a time of ongoing crisis. I argue that becoming sensitive towards air flow not only heightens our sensitivity for the affectivity of atmospheric processes but also for the different registers of our experience able to capture these effects.
Mission to Mars

Mars is a likely target for the first interplanetary mission. Current planning for a Mars expedition in the 2030s envisions a mission duration of between two and three years and a crew of six or seven people. Being confined with the same individuals for such a long period of time millions of miles from Earth may create psychological and interpersonal stress for the crewmembers and affect their ability to carry out mission goals. People have been on orbit for as long as 14 months with no apparent negative sequelae. However, this duration was relatively brief compared to a Mars mission, the orbiting crew had real-time communication with Mission Control and family and friends on the ground, immediate evacuation was an option, and Earth was always in sight. To fully appreciate the psychosocial and psychiatric issues affecting a Mars crew, it is important to examine some of the unique stressors of an expedition to the Red Planet.
On the measurement of tritium in DNA and its applications to the assay of DNA polymerase activity.

Publisher Summary This chapter discusses the measurement of tritium in DNA and its applications to the assay of the DNA polymerase activity. The study presented in the chapter evaluates three methods systematically: (1) methods for solubilization of nitrocellulose (millipore) filters and of 3 H-labeled DNA collected on both glass-fiber and nitrocellulose filters, (2) the effect of protein concentration on the collection, solubilization, and counting of 3 H-labeled DNA of both high-molecular-weight double-stranded and low-molecular-weight single-stranded forms, and (3) methods to reduce the “blank” in DNA polymerase reactions that employ relatively large quantities of 3 H-labeled dTTP as substrate along with the filter disc collection procedure for the measurement of reaction products. The results provide a basis for making recommendations about collection and counting of the particular macromolecules that are evaluated. Evaluation of methods for precipitation, collection, and counting of tritium-labeled DNA is described. Determination of optimal conditions for collection and counting of DNA polymerase-assay products is also discussed in the chapter.
Reduced z-axis technique for CT Pulmonary angiography in pregnancy—validation for practical use and dose reduction

The aim of this study is to determine the feasibility of using reduced scan range CT pulmonary angiography technique in pregnancy for pulmonary embolism (PE) and to quantify resulting dose reduction. This was a retrospective study. Eighty-four CTPA exams performed on pregnant women during 2004–2012. The scans were modified to create reduced anatomic coverage scans extending from aortic arch to base of heart. These were separately evaluated by two radiologists for PE and non-PE abnormalities. The results were then compared by the third radiologist with original radiology report and scans. Radiation dose reduction was evaluated prospectively in 36 patients as part of a quality control project. Two patients had PE and were successfully identified on reduced z-axis scans. Thirty-two exams were normal; rest had 60 pertinent and 16 had incidental findings. There were four incidental findings which included three benign thyroid nodules and one benign small lung nodule which were missed. None of these affected clinical outcome or management. There was 71 % radiation dose reduction. No PE or any important diagnoses are missed using reduced z-axis CTPA in pregnancy. There is a substantial radiation dose reduction. Hence, this technique is highly recommended in pregnancy.
Ultrastructural autoradiographic study of the uptake and intracellular localization of 35S-sulfate by developing human neutrophils.

The uptake and intracellular localization of /sup 35/S-sulfate was studied in developing neutrophils from normal human bone marrow by means of ultrastructural autoradiography in order to identify the pathway and sites of sulfate incorporation into glycosaminoglycans present in selected granule populations in these cell forms. Marrow cells were pulse labeled for 10 min in vitro at 37/sup 0/C with 200 ..mu..Ci/ml Na/sub 2/ /sup 35/SO/sub 4/ in either phosphate buffer (pH 7.4) or RPMI 1640 and cold chased for intervals up to 4 hr. Autoradiographic data indicated that promyelocytes involved in primary (azurophilic) granule synthesis showed a striking and preferential uptake of labeled sulfate with localization of silver grains over the Golgi and formative granules, while /sup 35/S-sulfate uptake by myelocytes engaged in secondary (specific) granule formation was minimal. A second period of /sup 35/S-sulfate uptake occurred during the final stages of neutrophil maturation extending from the metamyelocyte into the segmented neutrophil stage. /sup 35/S-sulfate concentrated in the Golgi and in condensing saccules arising from the concave Golgi face and was subsequently localized in small round to oblong (tertiary) granules formed in these cells. Labeled sulfate uptake by metamyelocytes and segmented neutrophils was appreciably less than noted for neutrophilic promyelocytes. more » Thus, autoradiography using /sup 35/S-sulfate permitted the delineation of three distinct phases of neutrophil maturation. Two of these phases involved the uptake of labeled sulfate which became incorporated into distinct types of cytoplasmic granules reported to contain sulfated glycosaminoglycans, viz., primary granules in promyelocytes and tertiary granules formed during late maturational stages of the neutrophilic leukocyte. « less
Chemical and enzymatic studies of deoxyribonucleic acid covalently linked to Ficoll.

Abstract Nucleotides and polynucleotides with terminal phosphoryl groups can be covalently linked in a carbodiimide reaction to water-soluble polysaccharides such as Ficoll and dextran. Small, dialyzable nucleotides can be converted to nondialyzable macromolecules of high molecular weight. Hybrid molecules of polynucleotides and polysaccharides have novel properties such as a reduced density in cesium chloride and modified end groups. Nucleotides and polynucleotides attached to Ficoll have been used in enzymatic studies of deoxyribonuclease, polynucleotide kinase, and DNA polymerases.
A Failure of Perspective: Moral Assumptions and Genocide

Samantha Power's book examines the American political tactic of doing nothing in response to the major genocides of the twentieth century. Power argues that American leaders are apathetic in response to genocide because politicians and the general public are suffering from a failure of imagination. Since genocide involves human anguish at an enormous scale, Power's contention is that human nature would rather turn away from recognizing such horrors. While Power's argument is persuasive, this Book Review argues that the reasons for apathy in response to genocide stem from a more fundamental failure of moral and legal perspective. This Book Review analyzes the AngloAmerican legal structure as an outgrowth of what Carol Gilligan refers to as an "ethic of justice." Because Anglo-American law is primarily concerned with defining and protecting individual rights, acting out of a sense of responsibility to prevent genocide can seem fraught with legal tension.