cssi/SciSciGPT-SciSciNet huggingface dataset:
Graft-related complications after abdominal aortic aneurysm repair: Reassurance from a 36-year population-based experience

Abstract Purpose: Graft-related complications must be factored into the long-term morbidity and mortality rates of abdominal aortic aneurysm (AAA) repair. However, the true incidence may be underestimated because some patients do not return to the original surgical center when a problem arises. Methods: To minimize referral bias and loss to follow-up, we studied all patients who underwent AAA repair between 1957 and 1990 in a geographically defined community where all AAA operations were performed and followed by a single surgical practice. All patients who remained alive were asked to have their aortic grafts imaged. Results: Among 307 patients who underwent AAA repair, 29 patients (9.4%) had a graft-related complication. At a mean follow-up of 5.8 years (range, Conclusions: This 36-year population-based study confirms that the vast majority of patients who undergo standard surgical repair of an abdominal aortic aneurysm remain free of any significant graft-related complication during their remaining lifetime. (J Vasc Surg 1997;25:277-86.)
Acidic and neutral polar NSO compounds in Smackover oils of different thermal maturity revealed by electrospray high field Fourier transform ion cyclotron resonance mass spectrometry

Abstract Negative ion electrospray ionization (ESI) coupled with high field Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) allows for the direct detection of acidic NSO compounds in petroleum. The technique requires no chromatographic separation, is able to distinguish 18 different compound classes (e.g., neutral nitrogen, carboxylic acids and oxygenates), and can identify ∼14,000 distinct masses by ultra-high mass resolution and mass accuracy. We previously studied three crude oils from different geological origins [Organic Geochemistry 33 (2002b) 743–759]. Here, we expand our research by comparing two source-equivalent Smackover oils of different levels of thermal maturity. We observe clear differences in the distribution of NSO compound classes, types (number of rings plus double bonds within a class), and number of alkyl carbons. With increasing thermal stress, the relative amount of sulfur and oxygen containing compounds decreases, condensation and aromatization of the polar cores increase, and the number of alkyl carbons decreases, reflecting the distribution of saturated hydrocarbons.
MCP-1-induced protein attenuates endotoxin-induced myocardial dysfunction by suppressing cardiac NF-кB activation via inhibition of IкB kinase activation.

Abstract Myocardial contractile dysfunction is a major consequence of septic shock, which is mainly mediated by nuclear factor-kappa B (NF-кB)-dependent production of inflammatory mediators in the heart. A novel zinc-finger protein, MCP-1-induced protein (MCPIP), is thought to have NF-кB inhibitory activity in certain cell cultures, but its pathophysiological consequence in vivo remains undefined. This study aims to clarify whether the anti-inflammatory potency of MCPIP contribute to amelioration of septic myocardial inflammation and dysfunction in vivo. Transgenic mice (TG) with cardiac-specific expression of MCPIP and their littermate wild-type (WT) controls were challenged with Escherichia coli LPS (10 mg/kg ip) and myocardial function was assessed 18 h later using echocardiography. LPS administration markedly deteriorated myocardial contractile function evidenced by reduction of the percentage of left ventricular fractional shortening, which was significantly attenuated by myocardial expression of MCPIP. MCPIP TG mice exhibited a markedly reduced myocardial inflammatory cytokines, less of iNOS expression and peroxynitrite formation, decreased caspase-3/7 activities and apoptotic cell death compared with LPS-treated WT mice. Activation of cardiac NF-кB observed in LPS-challenged WT mice was suppressed by the presence of MCPIP, as evidenced by decreased phosphorylation of IкB kinase (IKKα/β), reduced degradation of the cytosolic IкBα, and decreased nuclear translocation of NF-кB p65 subunit and its target DNA-binding activity. These results suggest that MCPIP has therapeutic values to protect heart from inflammatory pathologies, possibly through inhibition of IкB kinase complex, leading to blockade of NF-кB activation, and subsequently, attenuation of the proinflammatory state and nitrosative stress in the myocardium.
Prostacyclin (PGI2) inhibits the enhancement of granulocyte adhesion to Cuprophane induced by immunoglobulin G

Abstract Several purified plasma proteins have been found to influence leukocyte adhesion to artificial surfaces such as Cuprophane. This study demonstrates that albumin, fibrinogen, and hemoglobin inhibit leukocyte adhesion to Cuprophane while IgG, IgM, and thrombin enhance this reaction. The inhibitory effect of fibrinogen and enhancing effect of IgG on leukocyte adhesion to Cuprophane are likely due to modification of the Cuprophane surface by adsorbed proteins. Prostacylin (PGI2) was found to inhibit leukocyte adhesion to Cuprophane promoted by IgG. The inhibition of adhesion produced by PGI2 is concentration dependent and saturable. Other prostaglandins such as PGE1, 6-keto-PGF1 α, PGA2, and PGB2 at high concentration (100 μM) did not exert significant inhibiton of the same reaction.
Nuclear weapons in the Twenty-first century: From simplicity to complexity

*The author gratefully acknowledges the use of a model developed by Dr James Scouras in preparing Charts 1 through 6. Dr Scouras is not responsible for any of the analysis undertaken here, nor for any of the arguments or conclusions.
A Longitudinal Analysis of Satisfaction with Group Work

Satisfaction with group work is an important and frequently studied phenomenon that often determines whether a new tool, technology, or method is successfully implemented in an organization. We report on a longitudinal study of small groups which used regression to model how satisfaction with the process, outcome, and group evolves over multiple sessions as a function of performance measures and prior satisfaction levels. The results indicated that current performance contributed less to satisfaction as the study proceeded and by the end of the study period satisfaction with the process and outcomes were determined almost exclusively by prior satisfaction levels. In general, the conclusions were dependent on the point in time at which the analysis was conducted and on the object of satisfaction under consideration. The results highlight the importance of longitudinal studies, rather than one-shot approaches, for understanding individual satisfaction with group work.
High-performance bias-selectable dual-band mid-/long-wavelength infrared photodetectors and focal plane arrays based on InAs/GaSb Type-II superlattices

We report a bias selectable dual-band mid-wave infrared (MWIR) and long-wave infrared (LWIR) co-located detector with 3 μm active region thickness per channel that is highly selective and can perform under high operating temperatures for the MWIR band. Under back-side illumination, a temperature evolution study of the MWIR detector’s electro-optical performance found the 300 K background-limit with 2π field-of-view to be achieved below operating temperatures of 160 K, at which the temperature’s 50% cutoff wavelength was 5.2 μm. The measured current reached the system limit of 0.1 pA at 110 K for 30 μm pixel-sized diodes. At 77 K, where the LWIR channel operated with a 50% cutoff wavelength at 11.2 μm, an LWIR selectivity of ∼17% was achieved in the MWIR wave band between 3 and 4.7 μm, making the detector highly selective.
Partial sciatic nerve ligation results in an enlargement of the receptive field and enhancement of the response of dorsal horn neurons to noxious stimulation by an adenosine agonist

In this study we examined the effect of partial sciatic nerve ligation (PSNL) on the receptive field size, the baseline firing rate (BFR) and the response of spinal dorsal horn (DH) neurons to mechanical stimulation. In addition, we tested the effect of adenosine agonist, 5′-N-ethylcarboxamide-adenosine (NECA), and the adenosine antagonist caffeine on these parameters. Adult male Sprague-Dawley animals were used. One-third to one-half of the right sciatic nerve was tightly ligated. Unanesthetized animals were tested for their response to mechanical stimulation using Von Frey filaments and a blunt probe. The mean force that produced a paw withdrawal response in the operated animals was significantly less than the force that produced withdrawal in unoperated animals (median: 103.5 vs. 259.7; P < 0.001 for the paw ipsilteral to the ligation). Extracellular recordings were made from nociceptive-specific DH neurons located in laminai I–V of chloral hydrate-anesthetized rats. Recordings were made from 38 neurons in the right and 29 cells in the left DH of unoperated and 40 cells in right and 41 cell in the left DH of operated animals. The BFRs of neurons recorded in the operated animals were not significantly different from those recorded in normal animals. The mean receptive field size (RFS) of neurons (both ipsilateral and contralateral to the ligation) in the operated animals was significantly larger than the RFS of unoperated animals (right side: 180 ± 2.8 mm2 compared to 66 ± 2.3 mm2; left side: 93 ± 31 compared to 65 ± 21). Twenty-four percent of all neurons in the operated group had bilateral receptive fields; in contrast, only 3% of the neurons in the control animals showed bilateral receptive fields. To examine the effects of adenosine agonist and antagonist, NECA and caffeine were applied next to the recording electrode. The BFR and the RFS of neurons in control and operated animals were not affected by either NECA or caffeine. However, NECA significantly increased the duration of the response of neurons in the operated animals to noxious stimulation. These effects of NECA were blocked by caffeine. It is concluded that PSNL produces hyperalgesia in Sprague-Dawley rats that is associated with an increase in the RFS. In addition, in animals with PSNL, an adenosine agonist potentiates the response of nociceptive-specific neurons to noxious stimulation. Together these results suggest that PSNL alters the functional characteristics of DH neurons in part by changing purinergic transmission within the spinal cord.
Mobile applications in the hospitality industry

Purpose – The purpose of this study is to examine customer intentions to download mobile applications in the hospitality industry. Even though major hospitality companies offer the mobile applications, many customers have not utilized them. The results showed what encouraged customers to download mobile applications in the hospitality industry.Design/methodology/approach – The Technology Acceptance Model was applied for this research to explain customer intentions. College students were the target population of this study because they understand and adopt the technology well. Therefore, mobile applications will become a popular way to purchase goods and services when university students will have purchasing power.Findings – Even though major hospitality companies offer mobile applications, more than a half of respondents responded that they had not used mobile applications from the hospitality firms. The results showed that promotion information was not an only reason to download mobile applications; howe...
The 6-MP versus placebo clinical trial in acute leukemia

Background This article gives the status of clinical cancer research in the 1950's–1960's and tells the story of the development and conduct of the 6-mercaptopurine (6-MP) versus placebo clinical t...
Finite analytic method and its applications: a review

Abstract This paper describes the development of the finite analytic (FA) method and several engineering applications. In the finite analytic method, the governing differential equations are discretized into algebraic equations based on an analytic solution on the small computational element. Nine-point and five-point FA discretization schemes for two-dimensional Navier-Stokes equations are described for simple and complex boundaries. A 19-point FA discretization scheme for three-dimensional Navier-Stokes equations is also presented. The finite analytic method exhibits the properties of stability, convergence and grid independence. It is also shown that the FA method can be successfully used in problems with irregular domains. Evidence of the versatility of the FA method is demonstrated in successful modeling of two-dimensional turbulent sea breeze and three-dimensional channel flow with conjugate heat transfer.
Apogamy, apospory and parthenogenesis in the pteridophytes. II

There can be no doubt that the plants most favorable for the study of apogamy and apospory are the homosporous leptosporangiate Filicales, in many of which these deviations in life cycles have been found to occur in nature and also under cultural conditions. They are not, however, at present fully understood. In a large number of ferns, apogamy is known to be a constant phenomenon, but apospory of this nature has been found in only a single fern, Scolopendrium vulgare. The discovery of its constant occurrence was made as a result of the studies of the inheritance of apospory in certain ferns by Andersson-Kott6 (1931, 1932) and Andersson-Kott6 and Gairdner (1936). Both apogamy and apospory are sometimes described as abnormalities in the life cycle of a plant. It is commonly assumed that if one of these phenomena occurs in a life cycle, it must be followed by the other one. However, it is known that only apogamy occurs in some ferns, and that apogamy is the only way in which the sporophyte is reproduced in those cases. In some apogamous ferns apospory may occur, but it may also be found in non-apogamous ones. It is suggested by the writer that both apospory and apogamy may be considered as normal phenomena in the life cycle, and are not necessarily related. For a brief discussion of the independence of these phases in a life cycle, the reader is referred to an earlier paper by the writer (1939). Studies of apogamy and apospory in the Pteridophytes during the decade just past (1939-1949) have not been niumerous. Hence this group of plants, so favorable for cytological study of these phenomena and others of a physiological nature, has interested comparatively few botanists. During the past ten years, however, a number of papers have appeared on various phases of apogamy and apospory as follows:
Morphological control of particles generated from the evaporation of solution droplets: Theoretical considerations

Abstract Controlled homogeneous nucleation and crystal growth were examined as a means of controlling the morphology of particles obtained from the drying of solution droplets. Crystallization was expected to initiate at the surface of the solution droplet because of the concentration of the solute there. Consequently, the size of the droplet at the onset of crystallization might be important in determining the particle size if a shell was formed. However, using classical homogeneous nucleation theory, this crystallization size was found to be relatively unaffected by different parameters except for the mass of solute where lower density particles were found to be more probable for higher solute mass. The morphology of a particle is determined by the number of crystals formed, their habit and arrangement. Hence, the parameters that affect the activation of nuclei and crystal growth will control the morphology. These parameters include the temperature, evaporation rate of the solvent, crystal habit, solubility and mass of the solute. Given a solute, limited control of the morphology of the particle produced should be achievable through the temperature and vapor pressure (humidity) of the carrier gas. Although density and shape may be controllable, the aspect ratio of particles produced is not expected to be large because of the sphericity of the droplets.
Long-range correlations

Recent S-matrix arguments for the existence of nonplanar contributions to scattering amplitudes are reviewed and compared with experiment. The correct normalization of the two-particle correlation function is discussed. (auth)
Impact detection for smart automotive damage mitigation systems

Occupant safety and severity of vehicle damage are important factors in automotive vehicle design. Smart automobiles of the future could potentially use distributed smart material sensors and actuators in order to identify impact and take appropriate evasive or mitigative actions. This provides the motivation for this study. The first part of this study is focused on detecting the location and magnitude of impact, particularly for the case where the automotive structure is subjected to minimal damage. This is accomplished by developing a generalized algorithm using the Reissner-Mindlin plate theory, the Rayleigh-Ritz energy approach, and the Lagrangian-Hamilton principle. The level of performance of this methodology is demonstrated for impacts on a simply supported rectangular plate. Different case studies for static as well as impact loading with point as well as area contacts are presented. An algorithm using deconvolution for identifying impact location and magnitude has been developed and implemented. Additionally, the influence of damage on the structural vibratory content is studied via a frequency analysis. The modal analysis for undamaged and damaged plates, with nine different damage locations and six different damage sizes are performed. Changes in frequency and mode shapes are observed in regard to the severity of the damage.
Homogeneity of Pixley-Roy spaces

Abstract The Pixley-Roy space over the reals is shown to be homogeneous. The method of proof extends to a class of spaces that (1) is closed under finite products, open subsets, and the Pixley-Roy operator, and (2) contains a variety of first countable spaces including all n -manifolds, the rationals, irrationals, Cantor set, Alexandroff double arrow, and Sorgenfrey line. The Pixley-Roy space of a non-homogeneous space can be homogeneous.
MRI detection of abnormality in the corpus callosum and late-onset depression

A Case of a 75-year-old female with late-onset depression and MRI finding of a T2 signal hyperintensity in the anterior corpus callosum is presented. This case furthers the clinical anatomical association between late-onset mood disorders and frontal subcortical cere-brovascular disease. Depression 1:108–109 (1993). © 1993 Wiley-Liss, Inc.
Surotomycin Demonstrates Low In Vitro Frequency of Resistance and Rapid Bactericidal Activity in Clostridium difficile, Enterococcus faecalis and Enterococcus faecium

Surotomycin (CB-183,315) is an orally administered, minimally absorbed, selective bactericidal cyclic lipopeptide in phase 3 development for the treatment of Clostridium difficile-associated diarrhea. The aim of this study was to evaluate the emergence of resistance in C. difficile (ATCC 700057 and three recent clinical isolates from the restriction endonuclease analysis groups BI, BK, and K), vancomycin-susceptible (VS) Enterococcus faecalis (ATCC 49452), vancomycin-resistant (VR) E. faecalis (ATCC 700802), VS Enterococcus faecium (ATCC 6569), and VR E. faecium (ATCC 51559) under anaerobic conditions. The rate of spontaneous resistance was below the limit of detection (<10(-8) to <10(-9)) for surotomycin at 16 and 32× the MIC for all isolates tested. Under selective pressure by serial passage, C. difficile grew in a maximum of 4 μg/ml surotomycin (final MICs of 2 to 8 μg/ml [4- to 16-fold higher than those of the naive control]) at day 15, with the exception of the C. difficile BK strain, which grew in 16 to 32 μg/ml (final MICs of 8 to 32 μg/ml [16- to 64-fold higher than those of the naive control]). Enterococci remained relatively unchanged over 15 days, growing in a maximum of 8 μg/ml surotomycin (final MICs of 2 to 16 μg/ml [8- to 64-fold higher than those of the naive control]). Of the isolates tested, no cross-resistance to vancomycin, rifampin, ampicillin, metronidazole, or moxifloxacin was observed. Surotomycin at 20× MIC demonstrated equally rapid bactericidal activity (≥ 3-log-unit reduction in CFU/ml in ≤ 8 h) against naive and reduced-susceptibility isolates of C. difficile, VS Enterococcus (VSE), and VR Enterococcus (VRE), except for C. difficile BK (2.6-log-unit reductions for both). These results suggest that emergence of resistance to surotomycin against C. difficile, E. faecalis, and E. faecium is likely to be rare.
Dynamic video narratives

This paper presents a system for generating dynamic narratives from videos. These narratives are characterized for being compact, coherent and interactive, as inspired by principles of sequential art. Narratives depict the motion of one or several actors over time. Creating compact narratives is challenging as it is desired to combine the video frames in a way that reuses redundant backgrounds and depicts the stages of a motion. In addition, previous approaches focus on the generation of static summaries and can afford expensive image composition techniques. A dynamic narrative, on the other hand, must be played and skimmed in real-time, which imposes certain cost limitations in the video processing. In this paper, we define a novel process to compose foreground and background regions of video frames in a single interactive image using a series of spatio-temporal masks. These masks are created to improve the output of automatic video processing techniques such as image stitching and foreground segmentation. Unlike hand-drawn narratives, often limited to static representations, the proposed system allows users to explore the narrative dynamically and produce different representations of motion. We have built an authoring system that incorporates these methods and demonstrated successful results on a number of video clips. The authoring system can be used to create interactive posters of video clips, browse video in a compact manner or highlight a motion sequence in a movie.
Identification of a nasal nematode (Eucoleus boehmi) in greyhounds.

Eggs ofEucoleus boehmi were recovered from the faeces of greyhounds from three breeding farms and four racetrack kennels and from those of four greyhounds submitted for necropsy. Diagnosis was dependent on differentiation of the eggs ofE. boehmi, E. aerophilus andTrichuris vulpis. Quantitative fecal examinations conducted weekly for 24 weeks in one greyhound suggested that the egg shedding pattern ofE. boehmi is cyclical. Nasal swabs failed to reveal eggs ofE. boehmi, but nasal washings gave positive results. Because of its small size (15–40 mm) its location within the epithelial lining of the nasal mucosa, turbinates, and sinuses, and difficulty in differentiating the bipolar plugged eggs,E. boehmi probably occurs more often than is currently diagnosed.
The mandibular labial bar major connector

The lower labial bar is rarely indicated as a major connector for a removable partial denture. It can be used satisfactorily when large mandibular tori interfere with conventional lingual bar placement or when the lower teeth are severely lingually tipped and placement of a lingual bar is not possible.
Balanced sets andQ-polynomial association schemes

The notion of a balanced set of vectors is defined, and the classification of such sets suggested. A slightly stronger condition is considered for association schemes, with the following result. LetX be ad-class symmetric association scheme with Bose-Mesner algebraM and Krein parametersq ij h , and let E = Et (0 ≤t ≤ d) be any primitive idempotent ofM. For eachx ? X letx E denote the diagonal matrix withy, y entryE xy(y ? X). Define the representation diagramD E on the nodes 0, 1, ...,d by drawing an undirected arc between any nodesh, j for whichq tj h > 0. CallD E an augmented tree if it has a single loop, whose removal yields a tree. Writexy = i ifx, y ? X are ith associates (0 ≤i ≤ d).
Controllable adhesion using field-activated fluids

We demonstrate that field-responsive magnetorheological fluids can be used for variable-strength controllable adhesion. The adhesive performance is measured experimentally in tensile tests (a.k.a. probe-tack experiments) in which the magnetic field is provided by a cylindrical permanent magnet. Increasing the magnetic field strength induces higher peak adhesive forces. We hypothesize that the adhesion mechanism arises from the shear resistance of a yield stress fluid in a thin gap. This hypothesis is supported by comparing the experimentally measured adhesive performance to the response predicted by a lubrication model for a non-Newtonian fluid with a field-dependent yield stress. The model predictions are in agreement with experimental data up to moderate field strengths. Above a critical magnetic field strength the model over-predicts the experimentally measured values indicating non-ideal conditions such as local fluid dewetting from the surface.
Spin dephasing under nonlinear gradients: implications for imaging and field mapping.

This work examines the prototypical MR echo that would be expected for a voxel of spins evolving in a strong nonlinear field, specifically focusing on the quadratic z 2 -½(x 2 +y 2 ) field. Dephasing under nonlinear gradients is increasingly relevant given the growing interest in nonlinear imaging, and here we report several notable differences from the linear case. Most notably, in addition to signal loss, intravoxel dephasing under gradients creating a wide and asymmetric frequency distribution across the voxel can cause skewed and nonlinear phase evolution. After presenting the qualitative and analytical origins of this difference, we experimentally demonstrate that neglecting these dynamics can lead to significant errors in sequences that assume phase evolution is proportional to voxel frequency, such as those used for field mapping. Finally, simplifying approximations to the signal equations are presented, which not only provide more intuitive forms of the exact expression, but also result in simple rules to predict key features of the nonlinear evolution.
Theory of superconducting gap function △ in high-temperature layered materials

The energy-gap function Δ is a dominant feature in the long-wavelength optical spectrum of superconductors. We find Δ to be a function of qz as well as of temperature. We derive the equation that it satisfies and display some features of the solutions, including the gap-distribution function and the quasi-particle density of states, for a range of values of the parameters α, F, and tz.
Modeling and simulation for VLSI

The use of computer-aids in VLSI design has witnessed explosive growth, especially in the last decade. Beginning with the areas of circuit simulation and chip layout, the use of computer-aids has proliferated and now embraces high-level functional design and chip compilation at one extreme and fabrication equipment modeling and control at the other. This talk is intended to both highlight the broad issues of CAD for VLSI as well as specific concerns with technology and device modeling. The domains of applicability will be defined and contrasted. The growing industrial emphasis on high performance and application specific IC's both mandate the need for better CAD tools. The specific area of technology CAD is essential in process development and to aid understanding and visualization of details that are difficult to measure. The proliferation of workstations and the development of more CPU intensive algorithms both suggest the need for a diversity of solution methods, commensurate with the hardware constraints. The spectrum of algorithms for technology CAD will be discussed including analytical as well as numerical and even parallel computation methods. Numerous examples will be used to illustrate specific results as well as trends.
Microcracking of Monoclinic HfO2

Elasticity, internal friction, and thermal expansion were measured at temperatures up to 1500°C to characterize the micro-cracking behavior of HfO2. Crack-free HfO2 showed consistent, typical changes in these properties with temperature. Micro-cracked HfO2 showed hysteresis in the elastic moduli and thermal expansion on thermal cycling. Internal friction increased with microcrack healing. Repeated thermal cycling and high-temperature anneals markedly changed the microcrack system and a time- and atmosphere-dependent aging effect in microcrack formation was noted.
Consequences of Strain and Growth Kinetics on Growth Modes and Dislocation Formation in Strained Layer Epitaxy

We examine the growth modes of compound semiconductors grown by molecular beam epitaxy in lattice matched and strained layers. While in lattice matched layers it is possible to grow in the layer by layer mode by choosing proper growth conditions, in strained layers we find that for large strain, it is not possible to do so. This is due to the competition between surface strain energy which favors 3D growth and surface chemical energy which favors a layer by layer growth mode. The growth mode is shown to have significant effects on the nature of the dislocations generated beyond critical thickness.
Accelerating Student Learning in Kindergarten Through Grade 3: Five Years of OSEP-Sponsored Intervention Research

In this article the author provides the context for the 5 years of research conducted by the National Center on Accelerating Student Learning (CASL) and an introduction to key aspects of the work of the researchers. The following topics are discussed: methodology, student responsiveness to interventions, explicit and pragmatic instruction, implementation and adoption of interventions, and disseminating information about effective practices.
An inside view: VEGF receptor trafficking and signaling.

This review considers a revolving link between VEGF receptor endocytosis, trafficking, and signaling and their biological function.
Progression of left ventricular wall thickness during pressure-overload left ventricular hypertrophy

Pressure-overload in terms of decreased arterial compliance (C) and increased vascular resistance (Rs) was used in conjunction with a negative feedback control model to predict left ventricular (LV) wall thickness growth over a prescribed time period. The progression of left ventricular wall thickness growth was found to change proportionally with the peak systolic pressure and the extent of the combination of a reduction in C and an increase in Rs.
IN SEARCH OF IBN SĪNĀ'S “ORIENTAL PHILOSOPHY” IN MEDIEVAL CASTILE

Scholars have long debated the possibility of a mystical or illuminationist strain of thought in Ibn Sīnā's body of writing. This debate has often focused on the meaning and contents of his partly lost work al-Mashriqiyyūn (The Easterners), also known as al-Ḥikma al-Mashriqiyya (Eastern Wisdom), mentioned by Ibn Sīnā himself as well as by numerous Western writers including Ibn Rushd and Ibn Ṭufayl. A handful of references to what is called Ibn Sīnā's “Oriental Philosophy” are also found in the Castilian and Hebrew works of the Castilian Jew Abner of Burgos (ca. 1270-ca. 1347), known after his conversion to Christianity as Alfonso of Valladolid. Although the content of these citations has not been identified, it has been proposed that they may preserve otherwise unknown passages from Ibn Sīnā's lost work. This study considers the references to Ibn Sīnā's so-called “Oriental Philosophy” within Abner's writings and concludes that rather than preserving lost passages from Ibn Sīnā's writing, Abner's references were drawn primarily from Ibn Ṭufayl and offer no support for the argument of a possible mystical or illuminationist strain in Ibn Sīnā's thinking.
Retinoic Acid Receptor β Expression and Growth Inhibition of Gynecologic Cancer Cells by the Synthetic Retinoid N-(4-Hydroxyphenyl) Retinamide

Background: The synthetic retinoid N-(4-hydroxyphenyl) retinamide (4HPR) can inhibit the growth of tumor cells. Preliminary results from a clinical trial suggest that 4HPR may reduce ovarian cancer incidence. We examined the growth-inhibitory effects of 4HPR on gynecologic cancer cell lines in vitro and the role of retinoid receptors in modulating this effect. Methods: Twelve human gynecologic cancer cell lines (the ovarian cell lines-A224, AD10, UCI 101, UCI 107, SKOV3, 222, CP70, ML3B, and ML5; the cervical cell lines-HT3 and ME180; and the endometrial cell line-Hec 1A were tested for sensitivity to 4HPR (by assaying cell proliferation rates). Gel electrophoretic analysis of DNA fragmentation was used to measure programmed cell death (apoptosis). Specific retinoid receptor (retinoic acid receptor [RAR] and retinoid X receptor) messenger RNA (mRNA) levels were measured by northern blot hybridization. AD10 cells were stably transfected with human RARβ complementary DNA, and the effect of 4HPR on cell proliferation was examined. Results: 4HPR inhibited the growth of all 12 cell lines, but to varying degrees; Ic 50 values (i.e., concentrations that inhibit proliferation by 50%) ranged from 0.3 to 9 μM. Following 4HPR treatment, ovarian cancer cells that were sensitive to 4HPR (222, CP70, and UCI 101; Ic 50 <3 μM contained higher levels of RARβ transcripts than more resistant cells (AD10, ME180, Hec 1A, and A224; IC 50 ≥3 μM (2.8-fold; two-sided P =.006). Anchorage-independent growth of transfected AD10 cells expressing high levels of RARβ was totally abolished, even in the absence of 4HPR; transfectants expressing low levels of RARβ exhibited lower levels of anchorage-independent growth and grew more slowly in the presence of 4HPR than control untransfected AD10 cells. Conclusion: 4HPR inhibited the proliferation of ovarian cancer cells in vitro; RARβ expression appeared to be associated with this effect.
The influence of boundary layers on supersonic inlet unstart

A transverse air jet injected into a Mach 5 model inlet flow generated by an in-draft supersonic wind tunnel, is used to induce inlet unstart. Planar Laser Rayleigh Scattering (PLRS) from condensed CO2 particles in the tunnel flow is used to visualize the unsteady flow during unstart. Simultaneously, pressure traces along the wind tunnel are recorded with high speed pressure sensors attached to the bottom wall of the wind tunnel. A series of time synchronized PLRS images reveals that a shock system, followed by flow separation, originating from the jet injection nozzle propagates upstream. The flow then unstarts upon the arrival of the shock at the inlet. Studies conducted using three different inlet model geometries indicate that the presence of turbulent wall boundary layers strongly affect the unstart dynamics. It is found that relatively thick turbulent boundary layers result in faster inlet unstart, when compared to thin, laminar boundary layers.
Using units of CEM 43°C T90, local hyperthermia thermal dose can be delivered as prescribed

A randomized study was designed in dogs with spontaneous soft tissue sarcomas to gain information about the relationship between hyperthermia dose and outcome. The study compared two levels of thermal dose applied to dogs with heatable tumours, so it was necessary to deliver either a low (2-5 CEM 43°C T90) or high (20-50 CEM 43°C T90) thermal dose as precisely as possible. It was also desirable to have similar numbers of hyperthermia treatments in each thermal dose group. Identification of heatable tumours and randomization to high or low heat dose group was done during the first hyperthermia treatment. This was readily accomplished using mapping of temperatures in thermometry catheters, manual recording of thermal data, and visual inspection of raw thermal data with subsequent adjustment of the duration of the hyperthermia treatment. An analysis of precision of thermal dose delivery was conducted after approximately 50% of projected accrual had been met in a randomized phase III assessment of thermal dos...
A CLASSROOM DELPHI

The Delphi expert-consensus forecasting model has been widely applied since 1948 with mixed success. This paper presents a version of the Delphi, modified to organize and generate classroom discussion, and it describes an experiment in which this technique was used to teach a class in future urban environments. An analysis of the response patterns of the students suggests that student consensus does develop and that the technique is a successful nonlecture format.
Mining Eclipse Developer Contributions via Author-Topic Models

We present the results of applying statistical author-topic models to a subset of the Eclipse 3.0 source code consisting of 2,119 source files and 700,000 lines of code from 59 developers. This technique provides an intuitive and automated framework with which to mine developer contributions and competencies from a given code base while simultaneously extracting software function in the form of topics. In addition to serving as a convenient summary for program function and developer activities, our study shows that topic models provide a meaningful, effective, and statistical basis for developer similarity analysis.
EXPERIMENTAL HEAT TRANSFER AND FRICTION IN CHANNELS ROUGHENED WITH ANGLED, V-SHAPED AND DISCRETE RIBS ON TWO OPPOSITE WALLS

Experimental investigations have shown that the enhancement in heat transfer coefficients for air flow in a channel roughened with angled ribs is on the average higher than that roughened with 90 deg ribs of the same geometry. Secondary flows generated by the angled ribs are believed to be responsible for these higher heat transfer coefficients. In an effort basically to double the area of high heat transfer coefficients, the angled rib is broken at the center to form a V-shaped rib, and tests are conducted to investigate the resulting heat transfer coefficients and friction factors. Three different square rib geometries, corresponding to blockage ratios of 0.083, 0.125, and 0.167, with a fixed pitch-to-height ratio of 10, mounted on two opposite walls of a square channel in a staggered configuration, are tested in a stationary channel for 5,000 < Re < 30,000. Heat transfer coefficients, friction factors, and thermal performances are compared with those of 90 deg, 45 deg, and discrete angled ribs. The V-shaped ribs are tested for both pointing upstream and downstream of the main flow. Test results show that: (a) 90 deg ribs represent the lowest thermal performance, based on the same pumping power, and is essentially themore » same for the 2:1 change in blockage ratio, (b) low-blockage-ratio (E/D{sub h} = 0.083) V-shaped ribs pointing downstream produced the highest heat transfer enhancement and friction factors. Among all other geometries with blockage ratios of 0.125 and 0.167, 45 deg ribs showed the highest heat transfer enhancements with friction factors less than those of V-shaped ribs, (c) thermal performance of 45 deg ribs and the lowest blockage discrete ribs are among the highest of the geometries tested in this investigation, and (d) discrete angled ribs, although inferior to 45 deg and V-shaped ribs, produce much higher heat transfer coefficients and lower friction factors compared to 90 deg ribs.« less
Confinement versus pasture and traditional versus naturally raised finishing influences performance, carcass, and economic characteristics of early-weaned steers.

Angus × Simmental steer calves (n = 208) were used in a 2 × 2 factorial design of treatments to determine the effects of finishing management (confinement vs. pasture) and production system (traditional vs. naturally raised) on performance, carcass, and economic characteristics. Naturally raised steer diets did not contain monensin or tylosin and steers were not implanted, and pasture steer diets did not contain hay. Five-year average prices and carcass values were used for economic calculations. No interactions (P > 0.05) were found for most traits except days on feed and final BW. On average, steers on pasture were fed 10.5 d longer, were 5 kg lighter, ate 0.32 kg/d less (with no roughage), were more efficient, had $35.50 lower-feed costs, and had a $37.50 lower total input cost per steer. Pasture-fed steers had 4.5 kg lighter carcass weights, had 0.25 cm less backfat, had 28% more YG 1 and 2 carcasses, had 61 units less marbling, had 13% fewer Premium carcasses, had 20.5% fewer Choice carcasses, had $25.50 less carcass value, and returned $12.50 more per steer than steers in confinement. Naturally raised steers required 3.5 more days on feed, were 39 kg lighter, ate 0.5 kg/d more, were less efficient, had $20.50 higher feed costs, and had a $22.50 higher total input cost. Naturally raised steers had 26.50 kg lighter carcass weights, had 8.1 cm2 less ribeye area, had 64 units more marbling, had 20% more Premium carcasses, had 24.5% more Choice carcasses, had $45.50 less carcass value, and had a $68.50 extra cost compared with traditional steers. Naturally raised steers can be produced effectively for a $68.50 premium either in confinement or with a pasture finishing system. Pasture finishing was $12.50 more profitable than confinement feeding.
Three-Dimensional Vehicular Ignition Noise Radiation Patterns

Diagramme tridimensionnel de rayonnement du bruit electromagnetique de l'allumage d'un vehicule
Pathogenesis of hypertension and implications for its therapeutic management.

Excluding elevations in blood pressure secondary to primary hemodynamic changes and the relatively rare disorders in which hypertension is an accompaniment of extrarenal disturbances, hypertensive cardiovascular disease is attributable to dysfunction of the kidney. In a small group of patients, the elevation in blood pressure is mediated or intensified by a circulating pressor agent secreted by the kidney and detectable in the untreated plasma of the renal venous effluent. This unidentified pressor agent differs from renin and angiotensin, neither of which plays a primary role in the pathogenesis of renal hypertension. Most cases of chronic hypertension, including essential hypertension, are attributable to the loss of a normal renal function concerned in the maintenance of the normotensive state. This fuction appears to be humoral in nature, and replacement therapy with this humoral agent affords the prospect of a rational approach to the effective therapy of essential and related forms of hypertensive cardiovascular disease.
When Altruism Trumps Self-Interest: The Effect of Donation-Incentives on Motivation

People are often asked to complete tasks for small incentives. For example, researchers in a university setting frequently ask students to participate in studies in exchange for a small compensation. Despite the prevalence of these scenarios, many open questions remain regarding how incentives impact motivation in these contexts, and further if people accurately predict which incentives will be most motivating. In the current research, the authors test if traditional self-benefit incentives, such as offering money for performance, are predicted to be more (or less) motivating than donation-incentives, which donate an equivalent amount of money to charity. The authors find that people predict that self-benefit incentives are more motivating than donation-incentives, for both small and large amounts of money. Interestingly, however, they also demonstrate that people’s actual task motivation is greater for donation-incentives of small sums, and that this effect attenuates as size of the incentive increases. These findings suggest that individuals may be prone to systematic biases when predicting future motivation.
Purification and Characterization of an Induced Plasma Lipoprotein that Inhibits Streptolysin O.

SummaryA simple technic is described for separating streptolysin O inhibitor from the plasma of mice made refractory to the lethal effect of streptolysin O. Results of fractination and subsequent analysis indicate that the bulk of the inhibitory activity of refractory mouse plasma is associated with a lipoprotein of extremely low density (< 1.006) containing abundant lipid relative to protein. All classes of serum lipids are represented in the inhibitor-rich fraction; their concentrations, as well as the concentration of protein, are significantly greater than values obtained for comparable fractions from normal mouse plasma. Esterified cholesterol shows the greatest increment and seems most closely to parallel the inhibitory activity. It is suggested that the capacity of the induced lipoprotein to inhibit streptolysin O depends on an abundant content and unique orientation of lipids that are capable of interacting with the toxin.
From Ludlow to Chattanooga and beyond: A century of employee representation plans and the future of the American Labor Movement

Purpose The purpose of this paper is to examine the development of employee representation systems in the USA from the Ludlow Massacre of 1914 up to the events in 2015 at the Volkswagen plant in Chattanooga, Tennessee. The study begins with the strike at the Colorado Fuel and Iron Corporation which led to the deaths of several women and children. In the aftermath of Ludlow, John D. Rockefeller, Jr, visited the mines in 1915 and persuaded workers that an internal employee representation plan would serve their interests better than an outside trade union. Rockefeller’s influence shaped American industrial relations until the passage of the National Labor Relations (Wagner) Act in 1935, when company unions were outlawed. The ongoing decline of unions and collective bargaining has prompted academic speculation that a return to internal workplace committees might lead to a rejuvenated labor movement in the USA. Design/methodology/approach The study uses both archival materials and secondary sources to construct a narrative of one important element of industrial relations. It explains Wagner’s ban on company unions as a component of his economic agenda. Company unions provided a voice for a firm’s workers, but Wagner believed they were powerless to redistribute corporate wealth. The decline of American unions is so profound that they no longer serve an economic role in our capitalist system, but workers’ voice in the workplace remains an important consideration. Findings The key finding of this paper is that employee representation plans are not merely an industrial relations anachronism but continue to be relevant to today’s workplace. The paper compares an influential representation plan developed in 1914 by John D. Rockefeller, Jr, to current schemes of representation and argues that labor law should be modified to permit modern versions of the older “company unions”. Researchlimitations/implications Works councils play a crucial role in European labor relations, and they could do so in America if labor laws were modified to permit it. An exposition of the deep historical context of representation helps to legitimate the concept. Future research into specific cases, including an international perspective, would add to an understanding of the benefits and costs of representation. Originality/value The originality of this paper is its combination of a historical event and a contemporary case study that brings together a theme present in managerial history for over a century. By emphasizing the aims of Rockefeller, Jr. in 1914 and the objectives of the Volkswagen Company in 2014 in establishing a participatory workplace, we gain a long-term framework through which to evaluate a particular managerial technique. The paper also suggests ways to bring our labor laws into conformance with the idea of employee representation.
Quality Financial Reporting-An Important Transform

Based on the transform history of the relationship between enterprise and other market participators, this text brings up the removed phenomenon between the capital market and the company and its harm,and then introduced the concept of " Quality Finacial Reporting". Finally the text tries to bring the capital market into the business enterprise,s inner circulation by using QFR in order to improve the whole competitive ability of the interprise.