cssi/SciSciGPT-SciSciNet huggingface dataset:
Determination of Sorption Rate and Apparent Solid-Side Diffusivity of Pure H2O in Silica Gel Using a Constant Volume/Variable Pressure Apparatus

Silica gel-water vapor is commonly suggested as a working media for solar-powered desiccant cooling systems. Since the system can be regenerated at relatively low temperatures. In this paper the sorption rates of water vapor by regular density silica gel particles were measured in the pressure range of 1-25 torr using a constant volume/variable pressure apparatus. The sorption rate was determined from recorded time variation of water vapor pressure in a test unit of known volume during the sorption process. The mass transfer film resistance was eliminated by evacuating the system and by introducing pure water vapor into the test unit. The apparent solid-side diffusivity was obtained by matching the analytical solution of the simultaneous heat and mass transfer governing equations to the experimental data. The uptake measurements had been performed for three particle sizes of silica gel (150 {mu}m, l mm, and 3 mm). The tests were performed sequentially in small steps over a range of initial silica gel moisture content ranging from near zero up to 0.25 kg H{sub 2}O per kg dry silica gel. The effect of moisture content and particle size on the sorption rate and apparent diffusivity were determined. The effect of charging on time variationmore » of pressure was evaluated and used for correction on all sorption data.« less
Three-dimensional kinematics of hummingbird flight

Hummingbirds are specialized for hovering flight, and substantial research has explored this behavior. Forward flight is also important to hummingbirds, but the manner in which they perform forward flight is not well documented. Previous research suggests that hummingbirds increase flight velocity by simultaneously tilting their body angle and stroke-plane angle of the wings, without varying wingbeat frequency and upstroke: downstroke span ratio. We hypothesized that other wing kinematics besides stroke-plane angle would vary in hummingbirds. To test this, we used synchronized high-speed (500 Hz) video cameras and measured the three-dimensional wing and body kinematics of rufous hummingbirds (Selasphorus rufus, 3 g, N=5) as they flew at velocities of 0-12 m s(-1) in a wind tunnel. Consistent with earlier research, the angles of the body and the stroke plane changed with velocity, and the effect of velocity on wingbeat frequency was not significant. However, hummingbirds significantly altered other wing kinematics including chord angle, angle of attack, anatomical stroke-plane angle relative to their body, percent of wingbeat in downstroke, wingbeat amplitude, angular velocity of the wing, wingspan at mid-downstroke, and span ratio of the wingtips and wrists. This variation in bird-centered kinematics led to significant effects of flight velocity on the angle of attack of the wing and the area and angles of the global stroke planes during downstroke and upstroke. We provide new evidence that the paths of the wingtips and wrists change gradually but consistently with velocity, as in other bird species that possess pointed wings. Although hummingbirds flex their wings slightly at the wrist during upstroke, their average wingtip-span ratio of 93% revealed that they have kinematically ;rigid' wings compared with other avian species.
Government Matters: Welfare Reform in Wisconsin

Government Matters: Welfare Reform in Wisconsin. By Lawrence M. Mead. Princeton: Princeton University Press, 2004. 368p. $35.00 cloth, $22.95 paper. One of the most challenging aspects of welfare reform was that it made policy evaluation more difficult, especially after the Personal Responsibility and Work Opportunity Act of 1996 allowed states to shift from operating federal public assistance programs (or variants under waiver authority) to implementing programs of their own design. Analysts accustomed to studying a relatively stable set of nationally comparable social programs had to begin asking new, and sometimes startlingly basic, questions about the kinds of benefits that state and local governments were providing, to whom they were providing them, and on what basis. As a result, research on U.S. poverty and welfare reliance suffered a major setback at precisely the time when the need to track policy outcomes became especially critical.
Absorption coefficients of solid NH 3 from 50 to 7000 cm −1

Thin-film spectra of solid NH3 at a resolution of 1 cm−1 were used to determine its absorption coefficient over the range 50–7000 cm−1. The thin films were formed inside a liquid N2 cooled dewar using a variety of substrates and dewar windows. The spectra were recorded with two Fourier spectrometers, one covering the range from 1 to 4 μm and the other from 2.6 to 200 μm. The thickness of the films was measured with a laser interference technique. The absorption coefficients were determined by application of Lambert’s law and by a fitting procedure to the observed spectra using thin-film theory. Good agreement was found with the absorption coefficients recently determined by other investigators over a more restricted wavelength range. A metastable phase was observed near a temperature of 90°K and its absorption coefficient is reported. No other major spectral changes with temperature were noted for the range 88–120°K.
Subjective experiences on antipsychotic medications: synthesis and conclusions.

Objective: This report synthesizes the literature describing the phenomenology, clinical importance and biology of subjective responses to antipsychotic medications in schizophrenia. A patient's experience of an antipsychotic is important because unpleasant or dysphoric responses can impair therapeutic relationships, lead to medication non-adherence, and have direct negative effects on a patient's quality of life. Method: The author selectively reviewed early studies of subjective responses to antipsychotics and integrated this literature with the work of the other investigators in this special section. Results: There is substantial evidence that second-generation antipsychotics have advantages in causing fewer dysphoric responses when compared with first-generation agents. Clinical and neuroimaging studies suggest that dopamine blockade is an important determinant of many of these dysphorias. At this point in time it is unclear whether dysphoria results from extrapyramidal symptoms – particularly akathisia and akinesia – or whether they are a direct result of decreased dopamine activity. Conclusion: Clinicians and researchers should continue to monitor dysphorias in schizophrenia. Contributions by the authors in this supplement provide new and more refined methods for measuring subjective responses in future studies.
Clad Metal Circuit Board Substrates for Direct Mounting of Ceramic Chip Carriers

For a full realisation of the packaging advantages of leadless ceramic chip carriers, these devices will be surface mounted on large area printed circuit boards. However, thermal management and solder joint reliability concerns preclude the usage of conventional board materials and manufacturing processes in most high reliability applications. A new approach for achieving rugged, large area PCBs, incorporating thermal planes and the necessary thermal expansion match to chip carriers is described in this paper. The approach is based upon the use of a clad metal core substrate material fabricated from high conductivity copper and low thermal expansion rate Invar TM, a 36% nickel‐64% iron alloy. Mechanical, electrical and thermal properties of this clad metal are presented as well as techniques for adaption of PCB and porcelain/thick film technologies. Finally, other potential applications for this clad metal in the electronics industry are discussed.
Urinary tract and genito‐urinary suppurative infections due to anaerobic bacteria

Anaerobes have been involved in many different types of urinary tract infection. This review describes the microbiology, diagnosis and management of urinary tract and genito-urinary suppurative infections caused by anaerobic bacteria. The types of infections of the urinary tract in which anaerobes have been involved include para- or periurethral cellulitis or abscess, acute and chronic urethritis, cystitis, acute and chronic prostatitis, prostatic and scrotal abscesses, periprostatic phlegmon, ureteritis, periureteritis, pyelitis, pyelonephritis, renal abscess, scrotal gangrene, metastatic renal infection pyonephrosis, perinephric abscess, retroperitoneal abscess and other infections. The anaerobes recovered in these studies were Gram-negative bacilli (including Bacteroides fragilis and pigmented Prevotella and Porphyromonas sp.), Clostridium sp., anaerobic Gram-positive cocci and Actinomyces sp. In many cases, they were recovered mixed with coliforms or streptococci. The recovery of anaerobes requires the administration of antimicrobial therapy that is effective against these organisms. These antimicrobials include metronidazole, chloramphenicol, clindamycin, a carbapenem, cefoxitin and the combination of a penicillin and a beta-lactamase inhibitor. Percutaneous drainage, open surgical drainage or nephectomy might be indicated for abscesses.
Effects of Trinexapac-Ethyl Foliar Application on Creeping Bentgrass Responses to Combined Drought and Heat Stress

Simultaneous drought and heat stress is detrimental to turfgrass growth. Growth regulators may influence plant responses to stresses. The objective of this study was to determine effects of pretreatment with trinexapac-ethyl (TE) on creeping bentgrass (Agrostis stolonifera L.) responses to subsequent exposure to combined heat and drought stress. Plants were treated with TE (1.95 mL L1 [v/v], Primo Maxx) every 14 d for 42 d and then exposed to combined drought and heat (35°C) in growth chambers. Application of TE increased turf quality and relative water content and chlorophyll content during 21 d of stress. Trinexapac-ethyl-treated plants had increased growth rate and maintained constant canopy photosynthetic rate (Pn) and photochemical efficiency (Fv/Fm) during the stress period, while these parameters declined for the untreated control. Trinexapac-ethyl-treated plants maintained lower evapotranspiration rate (ET) under nonstressed control conditions, but higher ET at 21 d of stress. Trinexapac-ethyl-treated plants showed no differences from untreated plants in osmotic adjustment, and had lower levels of total nonstructural carbohydrates during the stress period. The study suggests that TE application enhanced turf performance under stress, as demonstrated by maintenance of higher turf quality and growth rate during a prolonged period of com bined stress. The beneficial effects of TE on bentgrass stress responses could be related to the maintenance of photosynthetic activities and greater level of cellular hydration. These and other published data indicate that use of TE on creeping bentgrass that seasonally experiences heat and drought stresses could benefit its performance.
Finite strain rock plasticity: stress triaxiality, pressure, and temperature effects

Abstract An elasto-plasticity theory is used to model the deformation of geological materials under various confining pressures and moderate temperatures. The effects of material hardening (or softening due to volumetric strains) are included, and the corresponding elasto-plastic rate constitutive relations are developed. To study the influence of pressure and temperature on the constitutive parameters, we use some published data of laboratory experiments on certain rocks. It is shown that over a wide range of pressures and low to moderate temperatures, when the rate effect can be ignored, the model can be used to describe the behaviour of geological materials. Based on this theory, dilatancy (i.e., inelastic volumetric expansion) of an intact granite is studied under conventional triaxial stress states. The effect of pressure and temperature on the magnitude of dilation and on the stress (measured relative to the peak stress) at the onset of dilatancy is investigated. It is found that, consistent with experimental data, the theory predicts this stress to be about 50% of the peak stress, but its specific value depends on pressure and temperature. As an illustration, stress-strain curves for intact granite at relatively shallow crustal depths are then predicted for possible application to the study of crustal deformation and for the prediction of fault behaviour.
A temperature-jump kinetic study of the binding of proflavine to poly I-poly C.

The kinetics of interaction between proflavine and poly I.poly C at 25°C, neutral pH, and moderate ionic strength have been studied by relaxation methods. The qualitative features of this system resemble those previously reported by Crothers and co-workers for proflavine–DNA and proflavine–poly A·poly U interactions–two relaxations are observed coresponding to a fast bimolecular step followed by a slower isomerization. These results can best be accommodated by a two-step mechanism leading from the free dye through an “outside-bound” complex to the intercalated complex. Quantitative comparison of the various rate constants for proflavine binding to different double-helical polynucleotides shows that the rates are slower for both ribohomopolymer pairs than for DNA. The rates for poly I·poly C are approximately three times faster than these for poly A·poly U.
Molecular Heterogeneity of Inherited Antithrombin III Deficiency

Abstract Inherited antithrombin III deficiency is associated with an increased risk of thromboembolism. Using recombinant-DNA techniques, we isolated a molecular probe for the antithrombin III structural gene and identified a common DNA polymorphism within the gene. We found that there is genetic heterogeneity in this disorder. In one family, the antithrombin III gene was deleted in affected members, whereas in another no deletion occurred. Use of the DNA polymorphism should allow identification and further characterization of abnormal antithrombin III genes. (N Engl J Med 1983; 308:1549–52.) Inherited deficiency of antithrombin III, an inhibitor of serine proteases in plasma, was first . . .
Measuring Properties for Material Decomposition Modeling

Inverse analysis methods were evaluated for determining thermal properties of materials for pyrolysis models. Experiments and analyses focused on determining the thermal conductivity and specific heat capacity of materials as a function of temperature and in different states. Experiments were designed to limit the properties (thermal conductivity, specific heat capacity) controlling the thermal response, allowing for more accurate determination of properties. Experiments and analyses were performed on three different materials: Ceramic, E-glass vinyl ester composite, and char/glass reinforcement. Results from the inverse analysis were compared with properties measured using other ASTM standard tests for measuring thermal properties. Properties were predicted to within 10 % of values from other standard test methods with quadratic and linear functions providing similar properties. Materials with more nonlinear variation in properties with temperature may require using quadratic functions to adequately predict properties.
Modeling of optical gain in ZnCdSe/ZnMgSSe quantum well lasers

A model to calculate the optical gain due to excitonic transitions is developed and used to calculate unstrained as well as strained ZnCdSe/ZnMgSSe multiple quantum well (MQW) lasers. Strain induced changes in energy band gap and effective masses of light and heavy holes are included in the gain coefficient and threshold current density calculations. The theoretical simulations are matched with the experimental data on compressively strained ZnCdSe-ZnSSe devices grown on GaAs substrates. Our calculations predict lower threshold current density for the tensile strained Zn.8Cd.2Se-Zn.2Mg.8S.03Se.97 quantum well lasers grown on InP substrates. Unlike the III-V strained layer quantum well lasers, the contribution to gain coefficient due to excitonic transitions is predominant in II-VI systems as the exciton binding energy is larger by a factor of 5. This results in a primary role for excitons in lasing, which has been verified experimentally.© (1994) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
One-dimensional quantum random walks with two entangled coins

We offer theoretical explanations for some recent observations in numerical simulations of quantum random walks (QRWs). Specifically, in the case of a QRW on the line with one particle (walker) and two entangled coins, we explain the phenomenon, called ``localization,'' whereby the probability distribution of the walker's position is seen to exhibit a persistent major ``spike'' (or ``peak'') at the initial position and two other minor spikes which drift to infinity in either direction. Another interesting finding in connection with QRWs of this sort pertains to the limiting behavior of the position probability distribution. It is seen that the probability of finding the walker at any given location eventually becomes stationary and nonvanishing. We explain these observations in terms of the degeneration of some eigenvalue of the time evolution operator $U(k)$. An explicit general formula is derived for the limiting probability, from which we deduce the limiting value of the height of the observed spike at the origin. We show that the limiting probability decreases quadratically for large values of the position $x$. We locate the two minor spikes and demonstrate that their positions are determined by the phases of nondegenerated eigenvalues of $U(k)$. Finally, for fixed time $t$ sufficiently large, we examine the dependence on $t$ of the probability of finding a particle at a given location $x$.
On the divisibility of the cycle number by 7

Abstract For every even p ⩾4, there exists a nonseparable cubic graph G with p vertices, such that the cycle number of G is divisible by 7.
Fragments of the Lunar Cataclysm

Meteorite samples returned from the Moon may reveal processes involved in the evolution of the early solar system.
Spiral-Layer Machining for Making Thin-Wall Structures

CNC machining is one of the most widely used manufacturing processes. While possessing good flexibility and fast cycle time, there are some restrictions imposed depending on the geometry of the part to be machined. One challenge often encountered is the machining of thinwall structures. The instability and deflection of the thin-wall causes difficulty for control of the machining condition, affecting the accuracy of the modeling and simulation of the process. This paper presents an alternative machining method called spiral-layer machining that could improve this condition using the concept of layer manufacturing technology and technologies that would reduce the machining force or tool-force variation and divert the force-vector. A case study of machining a turbine blade was conducted to verify the method. The result was successful in terms of stability and feasibility. Error correction techniques are being investigated to ensure good dimensional precision of the part.
Maximum matchings in random bipartite graphs and the space utilization of Cuckoo Hash tables

We study the the following question in Random Graphs. We are given two disjoint sets L,R with |L| = n and |R| = m. We construct a random graph G by allowing each x∈L to choose d random neighbours in R. The question discussed is as to the size μ(G) of the largest matching in G. When considered in the context of Cuckoo Hashing, one key question is as to when is μ(G) = n whp? We answer this question exactly when d is at least three. © 2012 Wiley Periodicals, Inc. Random Struct. Alg., 2012 © 2012 Wiley Periodicals, Inc.
The adjoint variety of SLm+1C is rigid to order three

Abstract I prove that the adjoint variety of SL m + 1 C in P ( sl m + 1 C ) is rigid to order three.
An introduction to the symposium on behavioral game theory

This article introduces the articles contained in the symposium on behavioral game theory. I break economic experiments studying game theory into three broad classes: (1) experiments studying and possibly modifying the assumptions that serve as foundations for game theory; (2) experiments that perform economic engineering, testing existing institutions with the aim of designing better ones; and (3) experiments designed to test theories which apply game theory to fields such as industrial organization.
C2 and CH rotational temperatures in diamond growth using CO2 laser-assisted combustion-flames

ABSTRACT Excited C 2 and CH species occur abundantly in diamond growth using C 2 H 2 /O 2 , C 2 H 2 /C 2 H 4 /O 2 and C 2 H 4 /O 2 flames. The irradiation of some flames by a continuous-wave (CW) CO 2 laser beam has resulted in increased optical emission intensity from the excited species and a change in the physi cal appearance of the flames due to resonant absorption of laser energy. Gas temperature in the flames is one of the most important parameters in the application of diamond growth. In atmospheric plasmas, the gas kinetic temperature is closely related to the rotational temperature of radical species in the plasmas. Optical emission spectroscopy (OES ) was used to obtain molecular spectra of the excited C 2 and CH species in the flames for a fixed gas ratio of C 2 H 2 /C 2 H 4 /O 2 flame at several laser energies. The rotational temperatures of CH were calculated using the Boltzmann plot method. In addition, synthetic C 2 molecular spectra were compared with the experimental spectra to obtain temperature by the intensity ratio of selected spectrum components. For each condition, the temperatures obtained using these methods were correlated with the quality, grain size, and growth speed of diamond films on cemented tungsten carbide (WC-Co) substrates. Keywords : rotational temperature, CO
30-nm InAs PHEMTs With $f_{T} = \hbox{644}\ \hbox{GHz}$ and $f_{\max} = \hbox{681}\ \hbox{GHz}$

We present 30-nm InAs pseudomorphic HEMTs (PHEMTs) on an InP substrate with record fT characteristics and well-balanced fT and fmax values. This result was obtained by improving short-channel effects through widening of the side-recess spacing (Lside) to 150 nm, as well as reducing parasitic source and drain resistances. To compensate for an increase in Rs and Rd due to Lside widening, we optimized the ohmic contact process so as to decrease the specific ohmic contact resistance (Rc) to the InGaAs cap to 0.01 Ω·mm. A 30-nm InAs PHEMT with tins = 4 nm exhibits excellent gm,max of 1.9 S/mm, fT of 644 GHz, and fmax of 681 GHz at VDS = 0.5 V simultaneously. To the knowledge of the authors, the obtained fT in this work is the highest ever reported in any FET on any material system. This is also the first demonstration of simultaneous fT and fmax higher than 640 GHz in any transistor technology.
A System for Seismocardiography-Based Identification of Quiescent Heart Phases: Implications for Cardiac Imaging

Seismocardiography (SCG), a representation of mechanical heart motion, may more accurately determine periods of cardiac quiescence within a cardiac cycle than the electrically derived electrocardiogram (EKG) and, thus, may have implications for gating in cardiac computed tomography. We designed and implemented a system to synchronously acquire echocardiography, EKG, and SCG data. The device was used to study the variability between EKG and SCG and characterize the relationship between the mechanical and electrical activity of the heart. For each cardiac cycle, the feature of the SCG indicating Aortic Valve Closure was identified and its time position with respect to the EKG was observed. This position was found to vary for different heart rates and between two human subjects. A color map showing the magnitude of the SCG acceleration and computed velocity was derived, allowing for direct visualization of quiescent phases of the cardiac cycle with respect to heart rate.
The Derivation and Characterization of Stromal Cell Lines from the Bone Marrow of p53−/− Mice: New Insights into Osteoblast and Adipocyte Differentiation

We have derived a series of clonal cell lines from the bone marrow of p53−/− mice that represent different stages of osteoblast and adipocyte differentiation. All cell lines show indefinite growth potential (>300 population doublings) and have generation times of 12–20 h. These cell lines have been grouped into three categories. The least mature clones are heterogeneous and appear to contain a subpopulation of stem cells, which can spontaneously generate foci that contain either adipocytes or mineralizing osteoblasts. The second category of clones are homogenous and clearly correspond to mature osteoblasts because they express high levels of the anticipated osteoblastic markers in a stable fashion and cannot differentiate into adipocytes even in the presence of inducers. The clones in the third category are the most unique. Initially they appeared to correspond to mature osteoblasts because they express alkaline phosphatase in a homogenous manner, secrete type I collagen, show a significant cyclic adenosine monophosphate response to parathyroid hormone, secrete osteocalcin, and mineralize extensively after only 4–7 days. However, in contrast to the mature osteoblasts, these clones can be induced to undergo massive adipocyte differentiation, and this differentiation is accompanied by the complete loss of expression of all osteoblastic markers except alkaline phosphatase. These observations indicate that some cells that have acquired all of the characteristics of mature osteoblasts can be diverted to the adipocyte pathway. Further characterization of these clones may be particularly relevant to osteoporotic conditions where increased adipocyte formation appears to occur at the expense of osteoblast formation.
The association of serum bilirubin levels on the outcomes of severe sepsis.

Purpose:Admission serum bilirubin levels have been incorporated into severity of illness scoring systems in critical illness as a marker of liver dysfunction. The purpose of our study is to determine the independent association of serum bilirubin with mortality in severe sepsis and septic shock.Methods:We conducted a retrospective study of adult patients admitted with severe sepsis and septic shock. We excluded patients with a prior history of liver disease. We identified the highest serum bilirubin within 72 hours of admission and stratified bilirubin levels into ≤1 mg/dL (normal), 1.1 to 2 mg/dL (abnormal up to 2 mg/dL), and >2 mg/dL. We sought to determine the independent association of hyperbilirubinemia with mortality and length of intensive care unit stay in persons with severe sepsis and septic shock.Results:A total of 251 patients met criteria for severe sepsis. In all, 200 patients had a bilirubin of 1 mg/dL. Of these 51, 12 had a bilirubin >2 mg/dL. Mortality...
Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH

There is a lack of fast and high resolution methods to measure metabolic activity of single cells in their native environment. Here we develop a straightforward, non-invasive and sensitive method to measure metabolic phenotype of single cells in a live tissue. By using NADH as optical biomarker and the phasor approach to Fluorescence Lifetime microscopy (FLIM) we identify cellular metabolic fingerprints related to different rates of oxidative phosphorylation and glycolysis. For the first time we measure a three dimensional metabolic gradient in the small intestine (SI) epithelia that appears tightly associated with epithelial cell proliferation, differentiation and the Wnt gradient. The highest free/bound NADH ratios are measured at the base of the crypt within the highly proliferative stem cells, indicating high levels of glycolysis. For the first time mouse small intestinal stem cells in intact live crypts are identified within the tissue by their metabolic fingerprint.
Identification of a Negative cis Element within the ZII Domain of the Epstein-Barr Virus Lytic Switch BZLF1 Gene Promoter

The Epstein-Barr virus (EBV) lytic switch gene, BZLF1, is tightly regulated in latently infected B cells. The BZLF1 gene promoter (Zp) contains several cis elements that have been previously shown to respond to inducers of the viral lytic cycle. These include four copies of an element referred to as the ZI domains and an element that contains a consensus CRE/AP-1 motif (ZII domain). In addition, Zp is autoregulated through two sites that bind the BZLF1 gene product Zta. The ZI domains have been shown to bind the ubiquitous cellular transcription factors Sp1 and Sp3 and/or the myocyte enhancer factor 2D (Liu et al., EMBO J. 16:143-153, 1997; Liu et al., Virology 228:9-16, 1997). Here we present a functional analysis of the ZII domain and show: (i) ATF-1 and ATF-2 appear to be the predominant cellular factors that bind to the CRE/AP-1 motif present in the ZII domain; and (ii) the region immediately upstream of the CRE/AP-1 motif contains a potent negative cis element, mutation of which results in a >10-fold increase in Zp activity. The negative cis element (ZIIR) in the ZII domain decreases both basal and induced Zp activity and thus is likely to play an important role in regulating reactivation of EBV. In addition, analysis of heterologous promoter constructs indicates that the function of ZIIR is context sensitive. Attempts to demonstrate a cellular factor binding to ZIIR have been unsuccessful, leaving unresolved the mechanism by which repression is mediated.
Group treatment of suicidal clients

Abstract This article provides an overview of essential aspects of starting and maintaining a counseling group for suicidal individuals.
Papillary adenocarcinoma of the rete testis with adjacent hyperplasia: a case report

An 81-year-old man had a papillary adenocarcinoma infiltrating the rete testis with involvement of the epididymis and paratesticular soft tissue. The tumor was composed of papillary structures to focally solid areas with cells having abundant eosinophilic to clear cytoplasm, markedly atypical nuclei, and brisk mitotic activity. Invasive growth and extensive necrosis were present. Morphology, immunohistochemistry, and medical history support the diagnosis. Our case represents the second documented case with foci of adenomatous hyperplasia adjoining the tumor.
Hierarchical Utilization Control for Real-Time and Resilient Power Grid

Blackouts in our daily life can be disastrous with enormous economic loss. Blackouts usually occur when appropriate corrective actions are not effectively taken for an initial contingency, resulting in a cascade failure. Therefore, it is critical to complete those tasks that are running power grid computing algorithms in the Energy Management System (EMS) in a timely manner to avoid blackouts. This problem can be formulated as guaranteeing end-to-end deadlines in a Distributed Real-time Embedded (DRE) system. However, existing work in power grid computing runs those tasks in an open-loop manner, which leads to poor guarantees on timeliness thus a high probability of blackouts. Furthermore, existing feedback scheduling algorithms in DRE systems cannot be directly adopted to handle with significantly different timescales of power grid computing tasks. In this paper, we propose a hierarchical control solution to guarantee the deadlines of those tasks in EMS by grouping them based on their characteristics. Our solution is based on well-established control theory for guaranteed control accuracy and system stability. Simulation results based on a realistic workload configuration demonstrate that our solution can guarantee timeliness for power grid computing and hence help to avoid blackouts.
Role of herniography in the diagnosis of occult hernias

Twenty-two patients with groin or incisional pain and normal physical examinations underwent herniography. Eight patients were found to have 11 unsuspected hernias. Seven were direct, two indirect, and two incisional. Six of nine groin hernias were recurrent. Exploration confirmed the herniographic findings in all patients. Follow-up evaluation of patients undergoing herniorrhaphy revealed resolution of symptoms. Ten of the 14 patients with normal herniograms were asymptomatic 3 months after herniography. In these 22 patients, herniography resulted in a savings of $31,000. We conclude that herniography is cost-effective and useful in patients with abdominal wall pain of obscure etiology.
A new statistical approach for fault-tolerant VLSI systems

A novel approach to the statistics of fault-tolerant VLSI systems is presented by compounding binomial distributions with a beta distribution. This technique was discovered in the analysis of fault-tolerant dynamic random-access memory (DRAM) chips. Manufacturing data supporting this method are shown and the application of the approach to standard fault-tolerance schemes is described. Special forms of these statistics for computer calculations are also discussed and examples are given. >
Primary source of income is associated with differences in HIV risk behaviors in street-recruited samples

The relationship between primary source of income and HIV risk behaviors and the racial/ethnic differences in risk behavior profiles among disadvantaged populations have not been fully explored. This is unusual given that the phenomenon of higher risk in more disadvantaged populations is well-known but the mechanisms remain unclear. We examined the relationship between primary source of income and differences in HIV risk behaviors among four racial/ethnic groups in the southern United States. Self-reported data on primary source of income and HIV risk behaviors were collected from 1494 African American, Hispanic, Asian, and White men and women in places of public congregation in Houston, Texas. Data were analyzed using calculation of percentages and by chi-square tests with Yates correction for discontinuity where appropriate. Data revealed that a higher proportion of whites were involved in sex for money exchanges compared to the other racial groups in this sample. The data suggest that similar street sampling approaches are likely to recruit different proportions of people by primary income source and by ethnicity. It may be that the study locations sampled are likely to preferentially attract those involved in illegal activities, specifically the white population involved in sex for drug or money exchanges. Research evidence has shown that people construct highly evolved sexual marketplaces that are localized and most unlikely to cross racial, ethnic, and socioeconomic or geographical boundaries. Thus, the areas that we sampled may have straddled a white sexual marketplace more than that of the other groups, leading to an over-representation of sex exchange in this group. Drug use was highest among those with illegal primary sources of income (sex exchange and drug dealing and theft), and they were also those most likely to have injected drugs rather than administered them by any other route (p < 0.001). In addition, bisexual or homosexual identification was reported by more respondents in the sex exchange as primary source of income category. The number of sexual partners in the last three months followed a similar pattern, with those whose primary source of income was drug dealing or theft reporting relatively high partner numbers. These data suggest that social disadvantage is associated with HIV risk in part by its association with drug and sex work for survival, and offers one variable that may be associated with the concentration of disease among those at greatest disadvantage by having an illegal and unstable primary income source.
Learning From Data: Recognizing Glaucomatous Defect Patterns and Detecting Progression From Visual Field Measurements

A hierarchical approach to learn from visual field data was adopted to identify glaucomatous visual field defect patterns and to detect glaucomatous progression. The analysis pipeline included three stages, namely, clustering, glaucoma boundary limit detection, and glaucoma progression detection testing. First, cross-sectional visual field tests collected from each subject were clustered using a mixture of Gaussians and model parameters were estimated using expectation maximization. The visual field clusters were further estimated to recognize glaucomatous visual field defect patterns by decomposing each cluster into several axes. The glaucoma visual field defect patterns along each axis then were identified. To derive a definition of progression, the longitudinal visual fields of stable glaucoma eyes on the abnormal cluster axes were projected and the slope was approximated using linear regression (LR) to determine the confidence limit of each axis. For glaucoma progression detection, the longitudinal visual fields of each eye on the abnormal cluster axes were projected and the slope was approximated by LR. Progression was assigned if the progression rate was greater than the boundary limit of the stable eyes; otherwise, stability was assumed. The proposed method was compared to a recently developed progression detection method and to clinically available glaucoma progression detection software. The clinical accuracy of the proposed pipeline was as good as or better than the currently available methods.
Self-Adaptive Data Caches for Soft-Error Reliability

Soft-error induced reliability problems have become a major challenge in designing new generation microprocessors. Due to the on-chip caches' dominant share in die area and transistor budget, protecting them against soft errors is of paramount importance. Recent research has focused on the design of cost-effective reliable data caches in terms of performance, energy, and area overheads, based on the assumption of fixed error rates. However, for systems in operating environments that vary with time or location, those schemes will be either insufficient or overdesigned for the changing error rates. In this paper, we explore the design of a self-adaptive reliable data cache that dynamically adapts its employed reliability schemes to the changing operating environments thus to maintain a target reliability. The proposed data cache is implemented with three levels of error protection schemes, a monitoring mechanism, and a control component that decides whether to upgrade, downgrade, or keep the current protection level based on the feedback from the monitor. Our experimental evaluation using a set of SPEC CPU2000 benchmarks shows that our self-adaptive data cache achieves similar reliability to a cache protected by the most reliable scheme, while simultaneously minimizing the performance and power overheads.
File grouping for scientific data management: lessons from experimenting with real traces

The analysis of data usage in a large set of real traces from a high-energy physics collaboration revealed the existence of an emergent grouping of files that we coined "filecules". This paper presents the benefits of using this file grouping for prestaging data and compares it with previously proposed file grouping techniques along a range of performance metrics. Our experiments with real workloads demonstrate that filecule grouping is a reliable and useful abstraction for data management in science Grids; that preserving time locality for data prestaging is highly recommended; that job reordering with respect to data availability has significant impact on throughput; and finally, that a relatively short history of traces is a good predictor for filecule grouping.Our experimental results provide lessons for workload modeling and suggest design guidelines for data management in data-intensive resource-sharing environments.
A tool for calculating the Palmer drought indices

[1] This paper presents a tool for calculating the Palmer Drought Severity Index (PDSI) and associated drought indices. The PDSI is a widely used drought index, yet the complexity and lack of transparency associated with the calculation of the PDSI makes it difficult for a researcher to independently calculate the index. Researchers are often forced to use PDSI values supplied by the National Climatic Data Center (NCDC) of the National Oceanic and Atmospheric Administration (NOAA) or some other third party. The MATLAB tool presented here is easy to use, thoroughly documented, and transparent. The tool was developed by checking an independently developed code against NCDC's FORTRAN code. Discrepancies between the MATLAB tool and the NCDC code are documented. Researchers using the tool will be able to easily calculate the Palmer drought indices for data inputs of any length and at any spatial scale.
Reasons Wrong and Right

The fact that someone is generous is a reason to admire them. The fact that someone will pay you to admire them is also a reason to admire them. But there is a difference in kind between these two reasons: the former seems to be the ‘right’ kind of reason to admire, whereas the latter seems to be the ‘wrong’ kind of reason to admire. The Wrong Kind of Reasons Problem is the problem of explaining the difference between the ‘right’ and the ‘wrong’ kind of reasons wherever it appears. In this article I argue that two recent proposals for solving the Wrong Kind of Reasons Problem do not work. I then offer an alternative solution that provides a unified, systematic explanation of the difference between the two kinds of reasons.
BUILDING PARENT/PROFESSIONAL PARTNERSHIPS: AN INNOVATIVE APPROACH FOR TEACHER EDUCATION

The value of collaboration between parents and educators is well-recognized. However, many preservice educators feel they lack the skills and confidence needed to establish and maintain effective partnerships with parents. This qualitative study was designed to explore one approach to improving teacher preparation with respect to parent/professional partnerships. An undergraduate course for preservice special educators was modified to provide students with multiple opportunities for meaningful interaction with parents of children with disabilities. One parent served as co-instructor of the course while six additional parents were embedded in the course for the entire semester. Pre- and post-intervention focus groups were conducted to describe the impact of this course innovation on the preservice students' dispositions and competencies regarding parent/professional partnerships. Results suggest that student dispositions changed from viewing parents as uncaring, uninvolved, and unknowledgeable to valuing t...
Association of fasting glucose with subclinical cerebrovascular disease in older adults without Type 2 diabetes

Aims To examine how fasting glucose and glucose tolerance are related to magnetic resonance imaging-assessed indicators of subclinical cerebrovascular disease and brain atrophy and their variation according to age, sex and education. Methods Participants in the present study were 172 healthy, community-dwelling older adults. An oral glucose tolerance test was administered and magnetic resonance imaging performed. Fasting, 2-h, and 2-h area-under-the-curve glucose levels, their associations with subclinical cerebrovascular disease and brain atrophy, and their respective interactions with age, sex and education were examined. Results A positive association between fasting glucose and subclinical cerebrovascular disease (but not brain atrophy) emerged; this association was more pronounced for participants with < 12 years of education; however, glucose tolerance was not related to subclinical cerebrovascular disease or brain atrophy. Conclusions Findings revealed a potential link between fasting glucose levels and the presence of subclinical cerebrovascular disease indicators — white matter hyperintensities and silent brain infarction — in older adults without diabetes and with an education level below high school. Additional research is needed to confirm these associations and to determine the need for interventions aimed at closely monitoring and preventing elevated glucose levels in this population to reduce the prevalence of subclinical cerebrovascular disease.
Modulation of glucose metabolism in macrophages by products of nitric oxide synthase

Nitric oxide (NO) is a product of L-arginine metabolism that suppresses cellular oxidative metabolism through the inhibition of tricarboxylic acid cycle and electron transport chain enzymes. The impact of NO synthase (NOS) activity on specific pathways of glucose metabolism in freshly harvested and overnight-cultured rat resident peritoneal macrophages, at rest and after stimulation with zymosan, was investigated using radiolabeled glucose. NOS activity was modulated through the L-arginine concentration in culture media and the use of its specific inhibitor, NG-monomethyl-L-arginine, and quantitated using radiolabeled L-arginine. Results demonstrated that NOS activity was associated with increased glucose disappearance, glycolysis, and hexose monophosphate shunt activity and, in line with the known inhibition of oxidative metabolism associated with the production of NO, with a decrease in the flux of glucose and butyrate carbon through the tricarboxylic acid cycle. In addition, the relative increase in glucose utilization that follows zymosan stimulation was enhanced by treatments that suppressed NOS activity. These results demonstrate that the characteristics of glucose metabolism by macrophages are, to a significant extent, determined by products of NOS.
Means to an end: Pro-government militias as a predictive indicator of strategic mass killing

Forecasting models of state-led mass killing are limited in their use of structural indicators, despite a large body of research that emphasizes the importance of agency and security repertoires in conditioning political violence. I seek to overcome these limitations by developing a theoretical and statistical framework that highlights the advantages of using pro-government militias (PGMs) as a predictive indicator in forecasting models of state-led mass killing. I argue that PGMs can lower the potential costs associated with mass killing for a regime faced with an internal threat, and might hence “tip the balance” in its favor. In estimating a series of statistical models and their receiver–operator characteristic curves to evaluate this hypothesis globally for the years 1981–2007, focusing on 270 internal threat episodes, I find robust support for my expectations: including PGM indicators in state-led mass killing models significantly improves their predictive strength. Moreover, these results hold even...
No iconic memory without attention

The experiments reported extend the findings of our earlier paper, (Mack, Erol, & Clarke, 2015) and allow us to reject Bachmann and Aru's critique of our conclusion (2015) that IM requires attention. They suggested our manipulations, which diverted attention from a letter reporting task in a dual task procedure where the task-cue occurred after the array disappeared, might only have affected access to IM and not the "existence of the phenomenal experience". By further decreasing the probability of reporting letters to only 10% and adding a final trial in which the letter matrix was either completely absent or distorted, we found more than half our subjects were unaware of its absence, or distortion i.e., were inattentionally blind. We take this as powerful evidence against the existence of any phenomenal experience component of iconic memory and consistent with the view that iconic memory demands attention and that conscious perception does as well.