cssi/SciSciGPT-SciSciNet huggingface dataset:
Internal relationship marketing: a key to enhanced supply chain relationships

Competitive market pressures within today’s contemporary business environments have encouraged the partnership of many supply chain members. Of particular interest is the development of successful relationships between firms in an effort to gain product and service quality and efficiency that would otherwise go left unclaimed. This research specifically identifies the need for supply chain members to foster healthier relationships within the firm in order to realize more fully success and obtain the benefits associated with external partnerships. The concept of internal relationship marketing is employed and a model is proposed to aid companies in identifying the variables associated with marketing to the internal customer. The motor carrier industry provides an appropriate service setting for the analysis, and implications for retaining the very best customer‐conscious frontline employees are outlined.
Tornado shelter-seeking behavior and tornado shelter options among mobile home residents in the United States

Residents of 401 mobile homes in Georgia, Mississippi, Illinois, and Oklahoma were surveyed after they heard a tornado warning. Most residents (69%) did not seek shelter during the warning. Half of those who sought shelter went to the frame house of a friend, neighbor, or relative, and 25% of those sought shelter in a basement or underground shelter. Some of the places where residents sought shelter were of dubious quality, such as their own mobile home, another mobile home, or in an out-building. Twenty-one percent of mobile home residents believed that they had a basement or underground shelter available as shelter during a tornado warning, and about half of those said they would drive to the shelter. Residents said they would drive if the shelter was more than 200 m away. Fifteen percent actually had a basement or underground shelter suitable as shelter within 200 m of their mobile home, but only 43% of the residents would use those shelters. The most common reason cited for not using the shelters was that they did not know the people who lived there. Likewise, a frame house or other sturdy building was within 200 m of 58% of the mobile homes, but only 35% of the residents stated they would use those houses for shelter. Thirty-one percent of mobile home residents had a ditch that was at least 0.5 m deep within 200 m of the mobile home. However, 44% of these ditches had utility lines overhead, 23% had water in them, and 20% had trees overhead. The limited tornado shelter options among mobile home residents in the United States needs to be incorporated into safety instructions so that residents without nearby shelter are allowed to drive to safer shelter.
Storm Spotting and Public Awareness since the First Tornado Forecasts of 1948

Abstract The history of storm spotting and public awareness of the tornado threat is reviewed. It is shown that a downward trend in fatalities apparently began after the famous “Tri-State” tornado of 1925. Storm spotting’s history begins in World War II as an effort to protect the nation’s military installations, but became a public service with the resumption of public tornado forecasting, pioneered in 1948 by the Air Force’s Fawbush and Miller and begun in the public sector in 1952. The current spotter program, known generally as SKYWARN, is a civilian-based volunteer organization. Responsibility for spotter training has rested with the national forecasting services (originally, the Weather Bureau and now the National Weather Service). That training has evolved with (a) the proliferation of widespread film and (recently) video footage of severe storms; (b) growth in the scientific knowledge about tornadoes and tornadic storms, as well as a better understanding of how tornadoes produce damage; and (c) th...
Fine Structure of the Large Neurons and Their Processes: Dendritic Thorns and Their Synapses

In the previous chapters, the location and gross morphology of the cerebellar nuclei were described, along with an estimation of cell numbers; the size, shapes, and dendritic and axonal characteristics of the neurons and their specific distributions within the segments of the dentate nucleus have also been detailed. On the basis of this information, cytological studies at a more refined level can be undertaken. Single cells can be examined at the fine structural level and their identifying features detailed. More important, it will now be possible to scrutinize the nature and quantity of the synaptic connections with other nuclear neurons and with axons of cortical and extracerebellar origins. For example, the large dentate neuron belongs to a prominent category defined by its size and the disposition of its axons. As its name implies, it is large and its axon undeniably projects out of the cerebellum via the superior cerebellar peduncle to red nucleus, thalamus, and other centers in the brain stem.
Office spirometry correlates with laboratory spirometry in patients with symptomatic asthma and COPD

Objectives Spirometry remains underutilized in the evaluation of obstructive lung disease. While office spirometry (OS) has been compared to formal laboratory-based spirometry (LS) in healthy subjects, the correlation has never been formally assessed in patients with symptomatic obstructive lung disease. The aim of this study was to investigate the correlation in this population. Methods We used a retrospective study design to analyze spirometry data from patients that underwent both OS and LS. Two flow sensing office (portable) spirometers were used and compared with laboratory-based (body plethymosgraph) spirometer. Accuracy and reliability were assessed using Bland Altman analysis. Results Among 185 patients with symptomatic obstructive lung disease, 129 had undergone both OS and LS. Of these, 107 patients had both tests performed less than 90 days apart and were included in final analyses. Mean age was 54 years with mean FEV1 of 1.97 L (65% predicted). Ninety-two patients had airflow obstruction, as determined by a FEV1/FVC ratio of Conclusions In patients with known asthma and chronic obstructive pulmonary disease (COPD), OS is accurate and reliable when compared to formal laboratory-based spirometry. Routine use of OS should be encouraged to improve spirometry utilization and healthcare outcomes in patients with Asthma and COPD.
Weaving a Tangled Web: Divergent and Reticulate Speciation in Boechera fendleri Sensu Lato (Brassicaceae: Boechereae)

Abstract Hybrid speciation is relatively common in plants compared to other well-studied groups. Polyploidy and apomixis are strongly associated with hybrid speciation, presumably due to the opportunities they provide for both reestablishing reproductive function in hybrids with incomplete chromosomal homology and creating rapid reproductive isolation in sympatry. Boechera, a species-rich genus closely related to Arabidopsis, is a particularly fertile ground for the study of hybrid speciation. Thirty-eight apomictic triploid hybrid species are currently recognized in Boechera. Recent research has shown that apomictic diploid hybrids, although very rare in angiosperms, are common in Boechera. Given this complexity, focused studies of individual species complexes are critical to understanding speciation and diagnosing biodiversity in Boechera. Here we analyze DNA sequences from seven nuclear loci and multilocus genotypes from 15 microsatellite markers in a group of closely related taxa formerly included in ...
The American College of Cardiology and Maintenance of Certification: The Path Forward.

![Figure][1] ![Figure][1] The complex situation presented by the American Board of Internal Medicine’s (ABIM’s) changes in Maintenance of Certification (MOC) requirements continues to be a top-of-mind issue for American College of Cardiology (ACC) leadership, staff, and most
Some Theoretical Aspects of Range Condition Assessment in the Presence of a Threshold

Ecologists have advocated the use of the concept of thresholds in range condition (or state) assessments. Despite this advocacy, there is virtually no theoretical research on range condition assessment in the presence of thresholds. As such, this chapter has three objectives. First, we use a Markov chain theoretic framework to characterize a rangeland whose spatial and temporal behavior is subject to the presence of a threshold. Next, we use this framework to demonstrate the formal relationship between the desirable and the undesirable sets of states of this rangeland. Finally, we compute the expected amount of time this rangeland spends in the desirable and in the undesirable sets of states. These two expectations can be interpreted as a binary measure of the condition of the rangeland under study.
Chaos, violence, and dynasty: politics and Islam in Central Asia

Eric McGlinchey's book offers a novel approach to understanding Central Asian politics and regime change. In this comprehensive study, the author insists that patronage politics are the present and...
Litigation Opportunism, or Systemic Change De Jure? The Ongoing Legal War and Impending Crucial Battles that May Change the NCAA…Or Confirm Its Unique Position in the World of Sport

US sport is unlike most of contemporary world sport. The demarcation between professional and amateur sport, on which the National Collegiate Athletic Association (NCAA) is built, is expressed by both major revenue producing sports at the highest level (Division I football and men’s basketball), and most other college sports programs that nowadays are facing severe budget cuts and downsizing. The NCAA remains the largest non-profit, tax exempt, education-based, sport association in America. 1,288 member institutions and conferences over three divisions provide what is generally admired both in the US and overseas as a wonderful opportunity for talented athletes to pursue their education and athletic excellence. At the same time, apparent inequities among the membership, inherent conflicts between the Association’s cornerstone principles, and the need for long-term financial well-being leading to increased commercialization, have been loathed by many. Critics desire protection of the student-athletes, fair treatment considering the revenue these athletes generate, and call for a mass overhaul of the intercollegiate athletics system. This is the environment in which the current legal battles are taking place.
Do Men Receive Information Required for Shared Decision Making About PSA Testing? Results from a National Survey

Most professional organizations, including the American College of Physicians and U.S. Preventive Services Task Force, emphasize that screening for prostate cancer with the prostate-specific antigen (PSA) test should only occur after a detailed discussion between the health-care provider and patient about the known risks and potential benefits of the test. In fact, guidelines strongly advise health-care providers to involve patients, particularly those at elevated risk of prostate cancer, in a “shared decision making” (SDM) process about PSA testing. We analyzed data from the National Cancer Institute’s Health Information National Trends Survey 2011–2012—a nationally representative, cross-sectional survey—to examine the extent to which health professionals provided men with information critical to SDM prior to PSA testing, including (1) that patients had a choice about whether or not to undergo PSA testing, (2) that not all doctors recommend PSA testing, and (3) that no one is sure if PSA testing saves lives. Over half (55 %) of men between the ages of 50 and 74 reported ever having had a PSA test. However, only 10 % of men, regardless of screening status, reported receiving all three pieces of information: 55 % reported being informed that they could choose whether or not to undergo testing, 22 % reported being informed that some doctors recommend PSA testing and others do not, and 14 % reported being informed that no one is sure if PSA testing actually saves lives. Black men and men with lower levels of education were less likely to be provided this information. There is a need to improve patient-provider communication about the uncertainties associated with the PSA test. Interventions directed at patients, providers, and practice settings should be considered.
Geomorphology and volcanology of Maat Mons, Venus

Abstract Full-resolution (FMIDR) Magellan radar backscatter images have been used to characterize the geology and volcanology of the volcano Maat Mons on Venus. This volcano has often been identified by remote sensing techniques as one of the volcanoes on the planet that could have been recently active, and is the highest volcano on Venus with a relief of ∼9 km. The summit of Maat Mons is characterized by a caldera complex ∼26 × 30 km in diameter with at least six remnant pit craters ∼10 km in diameter preserved in the walls of the caldera, suggesting that multiple small volume ( 1 km in diameter on the flanks. These pits appear to have formed by collapse with no effusive activity associated with their formation. No evidence for explosive volcanism can be identified, despite the (relatively) low atmospheric pressure (∼55 bar) near the summit. There is also a lack of evidence for lava channels, deformation features within the caldera, and thrust faults on the flanks, indicating that the physical volcanology of Maat Mons is simpler than that of typical martian and terrestrial shield volcanoes. Preservation of fine-scale (3–4 pixels) structures within the pit craters and summit pits is consistent with geologically very recent activity, but no evidence for current activity can be identified.
Optimal search strategies for ultrawide bandwidth signal acquisition

The important task of acquiring a spread-spectrum signal in a reasonable amount of time prior to commencing communication can be quite challenging for a receiver, especially when the transmission bandwidth is large. This paper investigates search techniques that minimize and maximize the mean acquisition time (MAT), a widely used performance measure of an acquisition receiver. We prove that a fixed-step serial search, a form of non-consecutive serial search, achieves a near-optimal MAT. In addition, we prove that the conventional serial search, in which consecutive cells are tested serially, results in the maximum MAT. Since these results are valid for any signal-to-noise ratio value, any fading distribution, and any detail of the detection layer, the paper provides search strategies that acquisition receivers should employ and search strategies that acquisition receivers should avoid.
A state profile of IT sophistication in nursing homes.

In healthcare, IT sophistication has been defined as the diversity and maturity of information system hardware and software that support clinical services. Clinical services relevant to this study include resident care management, clinical support and administrative activities in nursing homes. An IT sophistication survey previously validated in acute care settings and adapted for nursing homes was used to develop a state profile of Missouri nursing homes. The IT survey was disseminated via paper and electronic methods as chosen by a selected responder that had IT oversight and knowledge of IT stakeholders. A census of 199 respondents completed the survey, representing a 41% (199/491) response rate. Findings support recent literature indicating a higher percentage of nursing homes are still using technology for administrative purposes; however, there is growing recognition that technologies with greater functionality, is used more extensively for electronic and automated transfer of resident care information.
DACUM and Head Start: Working to Success

This article presents the Working to Success (WTS) model as a structured format to help parents and Head Start personnel not only meet the performance indicators of the Head Start Regulations, but also look to other disciplines for creative ideas. The model is based on basic DACUM principles and asserts that these principles can potentially be incorporated into Head Start curricula via the WTS model and could potentially promote family and educational development. Literacy, following directions, organization, teamwork, symbolic thinking, and cognitive, social, and linguistic development are just a few of the potential, not yet proven, benefits for Head Start-aged children. Finally, current DACUM and workforce education practitioners are challenged to consider the broad applications of workforce education principles. INTRODUCTION Developing A Curriculum (DACUM) workforce and training principles can be applied to many unique situations. One area of application is within Head Start programs. By using a modified version of the DACUM model and original material, the model Working to Success (WTS) has been developed. The WTS model is designed to introduce a modified DACUM curriculum into Head Start programs to potentially benefit student’s educational and family development. The WTS model is presented as one alternative to meet the existing goals Head Start programs. Following the presentation of the model and its application to the classroom, home, and community, a brief discussion relating to its potential impact on family and educational development will be reported. Finally, current DACUM and workforce education practitioners will be challenged to consider the broad applications of workforce education principles. THE DACUM MODEL Developing A Curriculum (DACUM) is a model developed more than 30 years ago by a Canadian university team as a fast and reliable way to identify job tasks for training curricula (Halazs, 97). In the WTS model, the DACUM technique of job analysis will be applied, in a very simplistic way, as it relates to the children enrolled in Head Start programs. Teachers and parents will be asked to think of identified work activities in terms of jobs and tasks. A job refers to the general description and name of what is to be accomplished by the child. The tasks refer to the necessary steps needed to complete the job.
Prediction of microscale plastic strain rate fields in two-phase composites subjected to an arbitrary macroscale strain rate using the materials knowledge system framework

Abstract In this work, a data-driven reduced-order model is presented to predict the microscale spatial distribution of the plastic strain rate tensor in an isotropic two-phase composite subjected to an arbitrary macroscopically imposed strain rate tensor. This model was built using the framework of localization linkages called Material Knowledge Systems (MKS), which has been demonstrated to exhibit a remarkable combination of accuracy and low computational cost. In prior work, the MKS framework was successfully used to predict the local strain rate fields in multiphase composites subjected to a selected macroscale strain rate tensor. In this work, the MKS framework is extended to include the complete set of all macroscale strain rate tensors that could be applied. This is accomplished by developing novel representations that allow a parametrization of the localization kernel over the complete space of unit symmetric traceless second-rank tensors and implementing them with the required fast computational strategies. The MKS localization linkage produced in this work was calibrated and validated to results from microscale finite element models.
The empirical effects of competition on third‐degree price discrimination in the presence of arbitrage

Since Borenstein (1985) and Holmes (1989), a theoretical and empirical literature has emerged that examines the effects of competition on third-degree price discrimination. Since transaction costs involved in conducting arbitrage are typically unobserved, empirical investigations in this area have largely been restricted to markets such as for air travel where arbitrage is difficult, if not impossible. Using an entirely novel dataset, this paper documents the effect of competition on price discrimination in the presence of arbitrage in the Canadian online sports betting market where prices for Canadian teams are higher than in the world market. I observe how the prices of Canadian teams change in real time in response to the presence of arbitrageurs that establish Canadian sportsbooks’ observable marginal opportunity costs. I exploit the existence of government betting outlets not subject to arbitrage to obtain reduced form counterfactual estimates of the extent to which competition affects price discrimination in the presence of arbitrage. In this new empirical environment, I find results consistent with the airline literature: competition reduces overall price dispersion and markups, but dispersion and markups shrink more for those in the “strong” market than the “weak” market.
On the effects of landscape configuration on summer diurnal temperatures in urban residential areas: application in Phoenix, AZ

The impacts of land-cover composition on urban temperatures, including temperature extremes, are well documented. Much less attention has been devoted to the consequences of land-cover configuration, most of which addresses land surface temperatures. This study explores the role of both composition and configuration—or land system architecture—of residential neighborhoods in the Phoenix metropolitan area, on near-surface air temperature. It addresses two-dimensional, spatial attributes of buildings, impervious surfaces, bare soil/rock, vegetation and the “urbanscape” at large, from 50 m to 550 m at 100 m increments, for a representative 30-day high sun period. Linear mixed-effects models evaluate the significance of land system architecture metrics at different spatial aggregation levels. The results indicate that, controlling for land-cover composition and geographical variables, land-cover configuration, specifically the fractal dimension of buildings, is significantly associated with near-surface temperatures. In addition, statistically significant predictors related to composition and configuration appear to depend on the adopted level of spatial aggregation.
Optically indcued alignement of gold nanorods and dichroism in plasmonic nanosuspesnions

We demonstrate soliton-mediated alignment of gold nanorods in colloidal suspensions, leading to polarization-dependent transmission. We discuss orientation-enhanced birefringence and dichroism due to disorder-to-order transition of nanorods resulting from the torque exerted by the soliton beam.
Fibrous dosage forms by wet 3D-micro-patterning: Process design, manufacture, and drug release rate.

Abstract Recently, we have introduced fibrous dosage forms prepared by 3D-micro-patterning of drug-laden viscous melts. Such dosage forms enable predictable microstructures and increased drug release rates, and they can be manufactured continuously. However, melt processing is not applicable if the melting temperature of the formulation is greater than the degradation temperature of the drug or of the excipient. In this work, therefore, a continuous wet micro-patterning process that operates at ambient temperature is presented. The excipient is plasticized by a solvent and the patterned dosage form is solidified by air drying. Process models show that the micro-patterning time is the ratio of the fiber length in the dosage form and the velocity of the fiber stream. It was 1.3 min in the experiments, but can be reduced further. The drying time is limited by the diffusive flux of solvent through the fibers: it was about 3 min for the experimental conditions. Furthermore, models are developed to illustrate the effects of fiber radius, inter-fiber spacing, viscosity of the drug-excipient-solvent mixture, and drying conditions on the microstructure of the dosage form. Both models and experimental results show that for a viscosity of the wet fibers of the order 103 Pa·s, the patterned microstructure is well preserved and the crossed fibers are well bonded. Finally, the drug release rate by the dosage forms is experimentally determined and theoretically modeled. The results of the experiments validate the models fairly.
Joint Control and the Selection of Stimuli from Their Description.

This research examined the role the two constituents of joint control, the tact and the echoic, play in producing accurate selections of novel stimuli in response to their spoken descriptions. Experiment 1 examined the role of tacts. In response to unfamiliar spoken descriptions, children learned to select from among six successively presented comparisons which varied in their color, shape, and border features. Repeated testing and training revealed that accurate selecting with new combinations of the same colors, shapes and borders, did not occur until after the children could themselves tact the individual color, shape and border features with the unfamiliar descriptions. Experiment 2 examined the role of self-echoics. Here, the stimulus features were given their familiar names, but the rehearsal of these names, while searching among the six successively presented comparisons, was impeded by a distracter task. Under these conditions selection of the correct comparison was found to depend on its position in the order of presentation. Correct comparisons presented earlier in the order, and presumably less effected by the distracter task, were more likely to be selected than correct comparisons presented later in the serial order. Taken together, these data suggest that generalized stimulus selection must be under joint tact/echoic control. The data also illustrate the distinction between mediated selection of a stimulus in response to its description (i.e., selection under joint control) and the traditional conception of an unmediated selection response evoked as a result of a heightened response probability in a conditional discrimination.
Genetic relationships within Vigna unguiculata (L.) Walp. based on isozyme analyses

Isozyme analyses of genetic diversity in Vigna unguiculata were performed to determine genetic relationships and level of genetic diversity between wild and cultivated cowpea. Thirty-four cultivated accessions of V. unguiculata, 56 wild accessions of V. unguiculata, and six accessions representing five related wild Vigna species were analyzed. Ten enzyme systems were polymorphic within Vigna unguiculata: AAT, ACO, G6PDH, DIAP, LAP, MUE, ME MDH, PRX, and SOD. Fourteen of 24 putative loci (58%) were polymorphic within wild V. unguiculata, but only one locus (4%) was polymorphic within cultivated cowpea; when five related Vigna species were examined, 21 of the 24 bands of activity showed polymorphisms (88%) adding 33 alleles to the 48 identified within V. unguiculata. In one F2 population of 68 plants (UCDVg 36 × UCDVg 21) a loose linkage was indicated between Diap-2 and G6pd-1 (χ2 = 15.39; p = 0.004) with an estimated distance of 36.0 cM ± 5.02 (recombination (r) = 0.31). Also in another F2 population of 38 plants (CB 88 × UCDVg 21) a loose linkage was indicated between Lap-1 and Prx (\gC2 = 9.62; p = 0.047) with an estimated distance of 39.8 cM ± 7.0 (r = 0.33). Total genetic diversity (HT) was 0.085 over all of the accessions including the one classified as V. nervosa. Within accession diversity (Hs) approached zero and between accession diversity (Dsi) was responsible for all of the genetic diversity present. Therefore the coefficient of gene differentiation (GST = DSTIIT) approached 1. Absolute gene differentiation (Dm) was 0.087. Two of the nine segregations in this study were skewed. In general, results of this study concurred with the taxonomic classification within V. unguiculata and provided a strong indication that a severe genetic bottleneck occurred during the domestication process of cowpea.
Mesh Insertion of Hybrid Meshes

A mesh insertion method is presented to merge a tool mesh into a target mesh. All the entities of the tool mesh are preserved in the output mesh while some of the entities of the target mesh are modified or eliminated in order to obtain a topologically conforming mesh. The algorithm can handle non-manifold surfaces formed of quadrilaterals and/or triangles as well as volumetric meshes based on hexahedra, prisms, pyramids and/or tetrahedra. Lower order elements such as beams can also be taken into consideration. A robust 2-steps advancing front algorithm is introduced to fill the narrow gap between the two mesh objects to obtain a complete crack-free connection. An efficient mesh data structure is developed to optimize the search operations and the intersection tests needed by the algorithm. Several application examples are provided to show the strength of the presented algorithm.
Abstract 4430: Genistein regulates non-coding RNA HOTAIR and epithelial-to-mesenchyme transition in renal cancer cells

Renal cell carcinoma (RCC) is one of the most common malignancies. Despite the development of therapeutic regimens, the prognosis of patients with RCC is poorly understood. Genistein, a naturally occurring isoflavone, has been reported to have anti-cancer effects on a variety of cancer types. While several studies have shown that genistein inhibits kidney cancer progression in various in vitro and in vivo models, the basic molecular mechanisms of genistein action have not been investigated in kidney cancer. In malignancies, long non-coding RNAs (lncRNAs) are differentially expressed in various tissues and have important functions in cell proliferation, motility and apoptosis. HOX transcript antisense RNA (HOTAIR) is a lncRNA localized in the Homeobox C gene cluster on chromosome 12. HOTAIR is necessary to target the polycomb repressive complex 2 (PRC2) in trans to the HOXD locus and can interacts with (PRC2, which enhances H3K27 trimethylation and represses the expression of tumor suppressors. HOTAIR is highly expressed in various cancers and involved in their progression and metastasis. In our study, we investigated the molecular mechanisms of genistein action through a novel pathway that represses HOTAIR. We found that HOTAIR expression is higher in renal cancer cell lines compared to normal controls. Genistein treatment was found to significantly decrease HOTAIR expression in renal carcinoma cell lines (786-O and ACHN cells). Genistein treatment also reduced expression of epithelial-to-mesenchyme transition (EMT)-related proteins, causing reduced cell migration, invasion, and increased apoptosis. We performed RNA immunoprecipitation assays, and found that genistein inhibits HOTAIR binding to PRC2. One of the other EMT markers, a tight junction protein ZO-1, is upregulated by genistein. We further investigated whether genistein represses PRC2 recruitment to the ZO-1 promoter by inhibiting binding of HOTAIR to PRC2. In this study, we revealed detailed mechanism of antitumor action of genistein. These insights indicate that genistein is a potent therapeutic agent not only for renal cancer but also for a broad spectrum of cancers. Citation Format: Mitsuho I. Sumida, Yuichiro Tanaka, Rajvir Dahiya, Soichiro Yamamura. Genistein regulates non-coding RNA HOTAIR and epithelial-to-mesenchyme transition in renal cancer cells [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 4430.
Warren Felt Evans: 19th-century mystic, wounded healer, and seminal theorist-practitioner of mind cure

The Methodist-Episcopalian minister-turned-physician and philosopher of healing Warren Felt Evans (1817-1889) was one of the earliest practitioners of mental healing, also known as "mind cure." Originating in New England in the second half of the 19th century, mind cure spread through the country in the 1880s. Drawing from Evans's unpublished journals, I recount his struggles with chronic ill health and his turn to the Quietist mystics and Swedenborg, and then to the mesmerist-turned-mental-healer P. P. Quimby to procure both healing for his ills and philosophical sanctification for his soul. The transformational route Evans traveled reflects the mythico-religious journey of the wounded healer who suffers through a creative illness on the way to becoming a healer himself. The article places Evans and the mind cure movement within late-19th-century Boston's medical and cultural milieu. Evans's approach to psychological healing is explored by focusing on his mind-body healing philosophy and mental therapeutics as described in his first 2 mind cure books The Mental Cure (1869) and Mental Medicine (1872). (PsycINFO Database Record
Multilayer Cyber-Physical Security and Resilience for Smart Grid

The smart grid is a large-scale complex system that integrates communication technologies with the physical layer operation of the energy systems. Security and resilience mechanisms by design are important to provide guarantee operations for the system. This chapter provides a layered perspective of the smart grid security and discusses game and decision theory as a tool to model the interactions among system components and the interaction between attackers and the system. We discuss game-theoretic applications and challenges in the design of cross-layer robust and resilient controller, secure network routing protocol at the data communication and networking layers, and the challenges of the information security at the management layer of the grid. The chapter will discuss the future directions of using game-theoretic tools in addressing multilayer security issues in the smart grid.
A case based human reliability assessment using HFACS for complex space operations

Multiple studies have shown that more than half of aviation, aerospace and aeronautics incidents are attributed to human error. Although many existing incident report systems have been beneficial for identifying engineering failures, most of them are not designed around a theoretical framework of human error, thus failing to address core issues and causes of the mishaps. In addition, the collection and classification of human error data can be a challenge, including the causal factors that impact human behavior. Therefore, it is imperative to develop a human error assessment framework to identify these causes [1]. The objective of this article is to provide a high-level literature overview and comparison of relevant human error assessment methods and provide an example of how one of these tools can be used to perform a human error analysis for complex space operations. The Human Factors Analysis and Classification System (HFACS) is one tool that can be used to categorize human error causal factors in a Space Operations environment. Due to the uniqueness of Space Operations and its complexity, there are very limited Human Reliability Assessment (HRA) tools specifically established for identifying and assessing human error. It is recommended that further research be done to fill the gap of HRAs, as it applies specifically to Ground Processing Operations.
Dangers of Withholding Treatment in Emergency and Prehospital Settings.

While a clear moral distinction between withholding and withdrawing treatments may be absent from other medical areas, emergency medicine’s unique circumstances surrounding acute life-threatening e...
Automated Speech Recognition in Adult Stroke Survivors: Comparing Human and Computer Transcriptions.

Objective Speech sound errors are common in people with a variety of communication disorders and can result in impaired message transmission to listeners. Valid and reliable metrics exist to quantify this problem, but they are rarely used in clinical settings due to the time-intensive nature of speech transcription by humans. Automated speech recognition (ASR) technologies have advanced substantially in recent years, enabling them to serve as realistic proxies for human listeners. This study aimed to determine how closely transcription scores from human listeners correspond to scores from an ASR system. Patients and methods Sentence recordings from 10 stroke survivors with aphasia and apraxia of speech were transcribed orthographically by 3 listeners and a web-based ASR service. Adjusted transcription scores were calculated for all samples based on accuracy of transcribed content words. Results As expected, transcription scores were significantly higher for the humans than for ASR. However, intraclass correlations revealed excellent agreement among the humans and ASR systems, and the systematically lower scores for computer speech recognition were effectively equalized simply by adding the regression intercept. Conclusions The results suggest the clinical feasibility of supplementing or substituting human transcriptions with computer-generated scores, though extension to other speech disorders requires further research.
CD209+ monocyte‐derived myeloid dendritic cells were increased in patients with leukemic cutaneous T‐cell lymphoma undergoing extracorporeal photopheresis via the CELLEXTM system

BACKGROUND/PURPOSE We previously reported that myeloid dendritic cells (mDC) were increased in patients with leukemic cutaneous T-cell lymphoma (L-CTCL) following extracorporeal photopheresis (ECP) using the Therakos UVAR XTS™ system. We now assessed monocyte-derived mDCs (Mo-DCs) in L-CTCL patients treated with the CELLEXTM photopheresis system. CD209, a transmembrane receptor, was used to define Mo-DCs. METHODS Peripheral blood samples from baseline pre-ECP and at Day 2, 1 month, 3 months, and 6 months post-ECP were analyzed by flow cytometry for Lin- HLA-DR+ CD123+ plasmacytoid dendritic cells (pDCs), Lin- HLA-DR+ CD11c+ mDCs, and CD209+ mDCs. The expression of CD209 mRNA was assessed by real-time PCR. RESULTS At baseline, 7 of 19 patients had lower than normal mDCs, and all patients had lower than normal CD209+ mDCs in peripheral blood mononuclear cells (0.005% in patients, n = 19, vs 0.50% in healthy donors, n = 7, P < .0001). The CD209+ mDC numbers only accounted for 3.28% out of total mDCs in patients compared with 66.51% in healthy donors. After treatment, the CD209+ mDC numbers showed increasing trends in patients. The average absolute numbers of CD209+ mDCs went up by 4.8-fold at 3 months (n = 10, P = .103) and by 6.4-fold at 6 months (n = 9, P = .100). CD209 mRNA expression went up in two patients responsive to therapy, parallel to CD209+ mDC numbers. L-CTCL patients achieved 70% overall clinical response rate (7/10) following ECP therapy with the CELLEXTM system. CONCLUSIONS Our results suggest that the CELLEXTM photopheresis system is effective for treating L-CTCL patients like the UVAR XTS™ system, and in vivo-generated Mo-DCs increase following ECP.
Feasibility of a citizen-driven hackathon to increase public engagement and solutions to address the opioid crisis

Background: Interdisciplinary approaches are needed to address complex societal problems, such as the opioid crisis. We sought to explore the feasibility and potential issues encountered in plannin...
Aging of persons with neurodevelopmental disabilities

Abstract A growing body of research informs our understanding of aging in individuals with neurodevelopmental or intellectual disorders, including autism spectrum disorder and Down syndrome. Due to diagnostic, medical, and technological advances, as well as improvements in formal and informal support, adults with neurodevelopmental disorders are living longer than ever before. This has resulted in a dramatic increase in the population of older adults living with neurodevelopmental disorders. Although neurodevelopmental diagnoses are typically made in childhood, features of neurodevelopmental disorders exist throughout the lifespan and significantly impact an individual’s functional abilities in late life. Functional and cognitive abilities, which vary widely within this population, play an important role in determining life expectancy as well as quality of life during the aging process.
Nonparametric cluster significance testing with reference to a unimodal null distribution.

Cluster analysis is an unsupervised learning strategy that is exceptionally useful for identifying homogeneous subgroups of observations in data sets of unknown structure. However, it is challenging to determine if the identified clusters represent truly distinct subgroups rather than noise. Existing approaches for addressing this problem tend to define clusters based on distributional assumptions, ignore the inherent correlation structure in the data, or are not suited for high‐dimension low‐sample size (HDLSS) settings. In this paper we propose a novel method to evaluate the significance of identified clusters by comparing the explained variation due to the clustering from the original data to that produced by clustering a unimodal reference distribution which preserves the covariance structure in the data. The reference distribution is generated using kernel density estimation and thus does not require that the data follow a particular distribution. By utilizing sparse covariance estimation the method is adapted for the HDLSS setting. The approach can be used to test the null hypothesis that the data cannot be partitioned into clusters and to determine the optimal number of clusters. Simulation examples, theoretical evaluations, and applications to temporomandibular disorder research data and cancer microarray data illustrate the utility of the proposed method. This article is protected by copyright. All rights reserved
3D Imaging using mmWave 5G Signals

The ability to create and steer beams, and the availability of large bandwidths have opened up the possibility of using mmWave 5G networks for radar-like sensing applications. In this paper, we introduce a signal processing pipeline that is able to process reflected OFDM-based communications waveforms and create radar images without affecting communications protocols or data throughput. An experimental demonstration system for this concept comprising a prototype basestation transmitter and an auxiliary imaging receiver is also presented. These two components are implemented with Si-based 28-GHz, 64-element phased array transceiver modules and software-defined radios. Measurement results show 3D radar images of indoor scenes with 2° angular and 15 cm ranging resolution using 5G-like communications waveforms at 28-GHz, without any effect on communication functionality.
Histoplasmosis neck mass – Case report and literature review a diagnostic dilemma

Abstract Histoplasmosis is a condition generally characterized by constitutional and pulmonary symptoms. Clinical manifestations include vague constitutional and pulmonary symptoms. It is unusual for it to present as a neck mass. In this report, we present the case of a 13-year-old girl admitted because of a growing neck mass. Serum and urine Histoplasma were negative, but complement fixation positivity, Computer Tomography (CT) chest and histological analysis and history of recent travel pointed to the diagnosis of Histoplasma. The objective of this report is to highlight diagnostic testing that can be used to prevent such a case from being undiagnosed.
Soy protein supplementation in men following radical prostatectomy: a 2-year randomized, placebo-controlled clinical trial.

Background Many studies have addressed effects of dietary supplementation with soy protein, but most have been inconsistent and few have been long-term studies in men. Objectives This study was a secondary analysis of body weight, blood pressure, thyroid hormones, iron status, and clinical chemistry in a 2-y trial of soy protein supplementation in middle-aged to older men. Methods Data were analyzed as secondary outcomes of a randomized controlled trial of dietary supplementation with 20 g/d soy protein isolate, providing 41 mg/d total isoflavones and 23 mg/d genistein, in 44- to 75-y-old men who were at risk of cancer recurrence following prostatectomy randomized to soy (n = 50) or a casein-based placebo (n = 43). Weight, blood pressure, and blood samples were collected at baseline, every 2 mo in year 1, and every 3 mo in year 2. Results Compared with casein, soy supplementation did not affect body weight, blood pressure, serum total cholesterol, calcium, phosphorus, and thyroid hormones. Serum ferritin concentrations doubled over 2 y in both groups (117-129%), whereas hemoglobin and hematocrit increased slightly. In an exploratory subgroup analysis of soy group data, weight increased in subjects producing equol but not in nonproducers. Blood pressure was reduced in nonequol producers but not in producers. Other endpoints were not affected by equol production status. Conclusions Soy protein supplementation for 2 y compared with a casein-based placebo did not affect body weight, blood pressure, serum total cholesterol, iron status parameters, calcium, phosphorus, and thyroid hormones. Exploratory analysis suggests that equol production status of subjects on soy may modify effects of soy on body weight and possibly blood pressure. This trial was registered at clinicaltrials.gov as NCT00765479.
Training Appalachian Kentucky Youth Cancer Advocates.

OBJECTIVES Kentucky has the highest cancer incidence and mortality rates in the United States, with the Appalachian region experiencing the highest of those rates. Cancer advocacy, which is defined as providing support to cancer patients and their communities, represents a means of decreasing the cancer cases in Appalachian Kentucky. This exploratory study examined the effects of advocacy training and experiential learning on Appalachian high school students' cancer advocacy attitudes and self-efficacy. METHODS The design of this study was a mixed-methods, one-group repeated measure with a group of participants from the Appalachian Career Training in Oncology (ACTION) Program (N = 9). The study assessed advocacy attitudes and self-efficacy before and after participants were provided advocacy training and participated in an advocacy event. RESULTS Participating students' attitudes and self-efficacy did not substantially change following the training and their participation in an advocacy event. Through their comments after the event, however, students seem eager to use their voices to influence the actions of state legislators. At the same time, they worry about the apathy of their community members to their cancer advocacy message. CONCLUSIONS Youth represent potentially powerful agents of advocacy that could help address the cancer burden in Kentucky. Participants in this study likely overestimated their advocacy abilities before learning more about advocacy and participating in the process. As such, additional trainings are likely necessary to increase students' self-efficacy, encourage them to share their stories, and help them overcome perceived barriers.
Forward Momentum: Providing Supportive Space for EdD Students’ Dissertation Progression through Weekly Online Writing Sessions

This essay describes an online writing group introduced to a CPED EdD program at a research-intensive, land-grant university during the summer of 2020 when the existing face-to-face program shifted to fully online delivery. The purpose of the writing sessions was to support EdD student practitioners with dissertation writing productivity by offering multiple weekly opportunities for synchronous writing sessions via Zoom online video conferencing. Although this new program is still in development, initial student feedback suggests that the writing sessions not only supported students’ dissertation progression, but it also established a sense of community and social support in an online environment. Lessons learned are shared, and we argue that this could be an ideal time to offer online writing sessions, especially since the pandemic will continue into the coming months.