cssi/SciSciGPT-SciSciNet huggingface dataset:
Applicability of Long Duration Exposure Facility environmental effects data to the design of Space Station Freedom electrical power system

Data defining space environmental effects on the Long Duration Exposure Facility (LDEF) are examined in terms of the design of the electrical power system (EPS) of the Space Station Freedom (SSF). The significant effects of long-term exposure to space are identified with respect to the performance of the LDEF's materials, components, and systems. A total of 57 experiments were conducted on the LDEF yielding information regarding coatings, thermal systems, electronics, optics, and power systems. The resulting database is analyzed in terms of the specifications of the SSF EPS materials and subsystems and is found to be valuable in the design of control and protection features. Specific applications are listed for findings regarding the thermal environment, atomic oxygen, UV and ionizing radiation, debris, and contamination. The LDEF data are shown to have a considerable number of applications to the design and planning of the SSF and its EPS.
A Novel Technique for Evaluating the Work of Adhesion

Abstract One of the basic problems which one encounters in bonding dissimilar materials such as glass and polymers is the development of internal stresses. These stresses arise primarily as a result of the difference in their thermal coefficients of expansion. Other stresses may also occur due to the processing history of the polymer, swelling of the polymer due to the absorption of gases in the environment or internal reaction products, and/or the loss of absorption of solvent from the adhesive. As a result, it is obvious that techniques designed to evaluate adhesion must evaluate the effects of these intrinsic stresses without modification by the external imposed stresses of the test. For example, Ahagon and Gent evaluate a work of detachment from the time average of the 180° peel force per unit width of the detaching layer.1 However, Gent and Hamed have recently shown that this mode of peeling involves deformation of the detaching layer due to bending.2 Similar problems are encountered in other techniq...
Adsorption from binary solutions of polar n-decyl derivatives and heptane onto alumina

Abstract The preferential adsorption of n -decanol, n -decylamine, n -decanoic acid, and ethyl octanoate from binary solutions with heptane onto alumina was studied. The net surface excess isotherms were measured for each system and resolved into component isotherms. The effect on the resolved isotherms of the cross-sectional area assumed for the polar adsorbate molecules is illustrated. The heat of immersion was measured in the n -decanol, n -decanoic acid, and ethyl octanoate solutions. Heats of immersion support the net and resolved isotherms. The alumina surface immersed in n -decanol/heptane and in ethyl octanoate/heptane solutions was found to be heterogeneous when analyzed in terms of a theoretical model.
Place-onas: shared resource for designing body tracking applications

Developments in computer vision technology have led to a plethora of new body tracking applications. These applications share a challenge in accounting for characteristics of the specific places in which they are intended to be used. We present the concept of Place-onas, representations of "typical" places, as a shared resource to support multidisciplinary team discussions during the development of body tracking applications. We present an example Place-ona drawn from ASSESS MS, a computer vision application that supports the clinical assessment of Multiple Sclerosis. We describe its usage, drawing out how it supported design work, and conclude with a discussion of future work.
Ultrasmall optical pickup module

For the application to the 5mm height optical drive, we have developed a small optical pick-up module within its dimension of 3.0×2.0×5.5mm, by integrating refractive and diffractive optical elements with laser diode and photo diodes assembly.
Potential labor force supply and replacement in Mexico and the states of the Mexican Cession and Texas: 1980-2000.

The purpose of this article is to carry forward the examination of potential labor force supply and replacement of men in Mexico into the 1980-1990 and 1990-2000 decades so that the possible future course of international migration between that country and the United States may be better anticipated. In addition to provide a degree of developmental perspective trends in potential labor force supply and replacement in Mexico since 1930-40 are presented. As a contrast "ratios of potential labor force supply and replacement in the southwestern United States--the states of the Mexican Cession and Texas which were formerly part of Mexico--also are shown for the 1980-1990 and 1990-2000 intervals." The results suggest that "in Mexico the projected number of males entering the labor force ages will be about 48 percent larger in the 1980s than in the 1970s....Fertility declined significantly in Mexico in the 1970s and therefore the number of new entrants to the labor force ages in the 1990s will decline...." The implications for international migration between Mexico and the United States are considered. (EXCERPT)
Second Assault of Male Survivors of Sexual Violence

Contemporary researchers treat sexual violence as a two-phase phenomenon: first, the actual violation, then, the second assault experience in which social institutions revictimize the survivor. Research on the second assault phenomenon has focused primarily on women with little attention to male survivors. Failure to incorporate experiences of male survivors in analyses of the second assault phenomenon denies the legitimacy of their experiences and reinforces harmful gender role socialization. Six case studies contribute to the current knowledge base regarding the experiences of male survivors of sexual violence. Particular emphasis is placed on difficulties males encounter when they report to or seek help from various social institutions.
Engineering transverse Bragg resonance waveguides for large modal volume lasers

We recently analyzed a new class of laser amplifier based on transverse Bragg reflection. We show that the unique properties of Bragg confinement make it possible through modal loss discrimination to achieve single-transverse-mode operation with transverse modal size that is an order of magnitude larger than in lasers that depend on total internal reflection for transverse confinement.
Testing the Economic Model of Crime:The National Hockey League's Two-Referee Experiment

During the 1998-99 season, the National Hockey League randomly varied the number of referees used across games, seemingly providing a rare opportunity to test directly the deterrence model. Combining experimental parameter estimates with an economic model, there is little evidence that the rate of offending changed substantially with the addition of a second referee. The reason, however, appears to be that the second referee had little impact on the probability of punishment. As a consequence, the experiment ultimately turns out to be of limited use for testing deterrence.
New species of Spartiella and Legeriosimilis from mayflies and other arthropod-associated trichomycetes from Nova Scotia, Canada

The digestive tracts of non-predaceous, aquatic insects and other arthropods living in moist habitats harbour a group of fungal and protistan microorganisms known as trichomycetes or “gut fungi”. A...
Self-Described Reasons for Premature Termination of Psychotherapy by Mexican American, Black American, and Anglo-American Patients:

This study investigated reasons given by Mexican American, black American, and Anglo-American patients for prematurely terminating psychotherapy. 74 patients who had prematurely left therapy in a public psychiatric outpatient clinic were interviewed. The three ethnic groups did not appear to be significantly different in their responses. However, dominant reasons reported for terminating therapy included negative attitudes toward therapists and perceiving therapy as of no benefit.
Direct nitrogen and phosphorus limitation of arbuscular mycorrhizal fungi: a model and field test

Author(s): Treseder, KK; Allen, MF | Abstract: Since mycorrhizal fungi constitute an important component of the soil–plant interface, their responses to changes in nutrient availability may mediate shifts in ecosystem function. We tested the hypothesis that initial soil nutrient availability may determine effects of nitrogen (N) and phosphorus (P) additions on the growth and community of arbuscular mycorrhizal (AM) fungi. Extraradical hyphal lengths and degree of root colonization of AM fungi were measured in control and fertilized plots along a soil fertility gradient in Hawaii. Responses of individual AM genera were assessed through immunofluorescent labeling. The AM biomass was increased by N and P additions in the N- and P-limited sites, respectively, and reduced by P fertilization in the fertile site only. The abundance of Scutellospora was lower under N than under P fertilization, whereas the incidence of Glomus was higher in the fertile site than the N-limited site. Gigaspora and Acaulospora did not vary among sites or treatments. Our results indicate that a decrease in AM abundance following nutrient additions cannot be assumed to occur and the effects may differ among AM genera and ecosystems with varying soil nutrients. Limitation of N and P may be one possible explanation.
Endoscopically-assisted resection of a choroid plexus vascular malformation traversing the cerebral aqueduct: technical case report.

OBJECTIVE: We report a case of a choroid plexus vascular malformation of the cerebral aqueduct, third, and fourth ventricles of an adolescent female that was resected with endoscopic assistance. CLINICAL PRESENTATION: A 14-year-old girl presented with a 1-week history of headaches and emesis. A noncontrasted computed tomographic scan of the head demonstrated enlarged lateral and third ventricles. Subsequent magnetic resonance imaging scans with and without contrast revealed an enhancing mass originating in the third ventricle, traversing the cerebral aqueduct, and terminating in the fourth ventricle. RESULTS: We used a suboccipital approach to remove the vascular malformation after endoscopically disconnecting it from its feeding and draining vessels in the third ventricle. Total excision was performed. Postoperative magnetic resonance imaging scans and arteriograms confirmed complete resection of the vascular malformation. CONCLUSION: Choroid plexus vascular malformations can exist intraventricularly and can be confused with a neoplasm. Resection of these intraventricular lesions can be performed with endoscopic assistance.
Reliability study for pediatric and adolescent gynecology case-based learning in resident education.

Abstract Objective To assess web-based teaching as a tool for resident education in pediatric and adolescent gynecology. Study Design Prospective Cohort involving 12 third year OB/GYN residents in a large university-based program. A second look reliability study on a previously utilized, web-based teaching case series in Pediatric and Adolescent Gynecology topics was evaluated. Residents' knowledge regarding the subject matter was assessed by pretest. After completion of the web-based teaching tool, a post test was administered. Residents were also given an opportunity to provide feedback regarding improvements to address future case series development for the tool and resident satisfaction in using this resource for resident education. Results The pre-test group mean score was 11.2 (58.9%), SD = 1.9. The post-test group mean score was 15.2 (80%), SD = 1.70. (P = 0.0002). Resident participants universally reported the case series was a useful teaching tool. Pooled results from 2005–2006 and 2007–2008 also yielded statistically significant scores from pre test to post test (power of >80% at the 95% confidence interval). Conclusion A computer-based learning tool is an effective resource to improve baseline knowledge among ob-gyn residents in the subspecialty field of Pediatric and Adolescent Gynecology.
Teacher-Student Relationships in Project Based Learning: A Case Study of High Tech Middle North County

Teacher-Student Relationships in Project Based Learning A Case Study of High Tech Middle North County By Jennifer Pieratt Claremont Graduate University 2011 The purpose of this study is to explore the relationship between pedagogy and teacher-student relationships. Researchers have hypothesized that these relationships can promote better student achievement, particularly among low-income students, and that instruction primarily shapes these relationships. Yet not enough is known about these relationships or their connection to student performance to move forward with school or teaching reforms. This study addresses this lack of knowledge. As such, it contributes to a stream of research that attempts to understand factors that contribute to student learning. The study setting is High Tech Middle North County (HTMNC), a charter school in San Marcos, CA. This case was chosen because of its unique and highly touted teaching practices based on relational and project-based pedagogies. Studying the implementation of these pedagogies and their meaning for the teachers and students at HTMNC will help researchers and educators better understand the role pedagogy plays in fostering teacher-student relationships. Through collegial relationships established by a project-based pedagogy, HTMNC teachers were able to develop positive relationships with students, allowing them to use these relationships to personalize curriculum and differentiate instruction, resulting in increased student motivation and engagement.
A novel approach to provide relay coordination in distribution power systems with multiple reclosers

Electricity customers are increasingly sensitive to electric power interruptions and high reliability has become a growing expectation. Due to this increased attention in electric power distribution system reliability, more protection devices are being installed and significant investment is made to help improve grid reliability. The increased usage of protective devices in distribution systems makes coordination among the protective devices challenging. In many cases, proper coordination cannot be achieved with traditional time-overcurrent schemes. In addition to the coordination problem, the traditional approach might experience longer clearance time intervals. In order to achieve feasible coordination in a radial distribution system with multiple reclosers, a new approach is proposed. In this method, distance relays are applied along with overcurrent relays and reclosers to provide the expected proper coordination. The paper includes detailed case study that represents the performance of the proposed scheme in a multi-recloser distribution system.
Comparative tests of isospin-symmetry-breaking corrections to superallowed 0 + → 0 + nuclear β decay

We present a test with which to evaluate the calculated isospin-symmetry-breaking corrections to superallowed ${0}^{+}\ensuremath{\rightarrow}{0}^{+}$ nuclear $\ensuremath{\beta}$ decay. The test is based on the corrected experimental $\mathcal{F}t$ values being required to satisfy conservation of the vector current (CVC). When applied to six sets of published calculations, the test demonstrates quantitatively that only one set, the one based on the shell model with Saxon-Woods radial wave functions, provides satisfactory agreement with CVC. This test can easily be applied to any sets of calculated correction terms that are produced in future.
Real-time estimation of human attention field in LWIR and color surveillance videos

Knowing the visual attention field of a monitored subject is of great value for many applications including surveillance and marketing. This paper proposes first to track peoplepsilas bodies, and then estimates visual attention field for each human using head pose information. The proposed head pose technique aims at estimating the yaw angle only. The method is shown to operate on monocular color camera sequences and is further refined with the data from a thermal sensor. In typical monocular tracking sequences the resolution of the head is very low and parts of the head are occluded with the face often invisible to the camera. We propose a method of combining a skin color detector with the direction of motion in a probabilistic way. We show how head profile obtained from the thermal sequence can be used to further improve the result.
Adrenomedullin (AM) and adrenomedullin binding protein (AM-BP) in the bovine mammary gland and milk: Effects of stage of lactation and experimental intramammary E. coli infection

Abstract Adrenomedullin (AM) has been characterized as an endogenous tissue survival factor and modulator of many inflammatory processes. Because of the increased susceptibility of the mammary gland to infection during the time surrounding parturition in the cow, we investigated how milk and tissue content of AM and its binding protein (AM-BP) might be affected by the stage of lactation and the udder health status. Milk and mammary biopsy samples were obtained from Holstein cows 21 days prior to and at various times after calving to represent the dry period and early and mid-stages of lactation. Additional cows received an intramammary challenge with Escherichia coli for immunohistochemical characterization of AM and AM-BP. Milk AM concentrations were relatively constant across the stages of lactation while AM-BP increased two-fold ( P P P E. coli challenge, AM increased in epithelial cells surrounding mammary alveoli presenting high levels of SCCs. The data suggest that AM and AM-BP are cooperatively regulated in the mammary gland during lactation; changes in localized tissue AM and AM-BP content reflect a dynamic regulation of these tissue factors in the bovine mammary gland consistent with their protective effects within inflamed tissue.
Adult attachment and cortisol responses to discussions with a romantic partner

This study examines the effects of actor and partner attachment security on cortisol responses to discussions of personal and relationship concerns with a romantic partner. Dating couples (N = 30) completed two 20-min discussions and provided saliva samples at 4 time points before and after. Hierarchical linear modeling revealed that among women, higher levels of partner avoidance predicted greater cortisol reactivity to both discussions and among men, higher levels of actor anxiety predicted greater reactivity to the relationship concern discussion. These findings extend previous work by demonstrating that the effects of attachment on physiology vary by gender and by discussion context, which informs our understanding of how individual differences in attachment moderate the effects of romantic relationships on health. The quality of close relationships has a powerful influence on physical health. Individuals in less distressed, higher quality marriages are in better health (Burman & Maroglin, 1992) and experience smaller declines in health as they age (Umberson, Williams, Powers, Liu, & Needham, 2006) than individuals in low-quality marriages. One pathway by which relationship quality may ultimately affect health involves activity in the hypothalamic–pituitary–adrenal (HPA) axis and production of the hormone cortisol. Short-term
Rotational-beam power theorems

General power theorems for rotational electron beams and some moving plasmas are derived by using three sets of variables: Clebsch variables, Lin's variables, and polarization variables. In each case, the most general power theorem, with unspecified linear operators, is given and for the polarization-variable case this is specialized to some cases of interest. Unfortunately, the physical interpretation of the variables used is not always clear, and the physically unmeasurable variables may not always behave as measurable ones would, so that the theorems are of limited usefulness.
Telomerase activity is not a prognostic factor in chronic lymphocytic leukemia

Abstract We measured telomerase activity (TA) in bone marrow samples from 214 patients with CLL and correlated it with patients’ characteristics and survival. In >50% of cases (126/214; 59%) no detectable TA was found. There was no difference in TA between previously treated ( n =153) and untreated ( n =61) patients ( P =0.4), or patients with various Rai (0–IV) stages ( P =0.85). TA correlated significantly with white blood cell and lymphocyte count ( P =0.02 and 0.01, respectively) but not with bone marrow cellularity, β2-microglobulin (β2M), or other patient characteristics. Patients who had no TA had slightly lower β2M and lower lymphocyte counts ( P =0.5 and 0.04, respectively) as compared with patients with detectable TA. However, there was no correlation between TA and survival. This data suggests that TA may not play a significant role in the clinical behavior of CLL.
Gender differences in the incidence and prevalence of patellofemoral pain syndrome

The purpose of this investigation was to determine the association between gender and the prevalence and incidence of patellofemoral pain syndrome (PFPS). One thousand five hundred and twenty-five participants from the United States Naval Academy (USNA) were followed for up to 2.5 years for the development of PFPS. Physicians and certified athletic trainers documented the cases of PFPS. PFPS was defined as retropatellar pain during at least two of the following activities: ascending/descending stairs, hopping/jogging, prolonged sitting, kneeling, and squatting, negative findings on examination of knee ligament, menisci, bursa, and synovial plica, and pain on palpation of either the patellar facets or femoral condyles. Poisson and logistic regressions were performed to determine the association between gender and the incidence and prevalence of PFPS, respectively. The incidence rate for PFPS was 22/1000 person-years. Females were 2.23 times (95% CI: 1.19, 4.20) more likely to develop PFPS compared with males. While not statistically significant, the prevalence of PFPS at study enrollment tended to be higher in females (15%) than in males (12%) (P=0.09). Females at the USNA are significantly more likely to develop PFPS than males. Additionally, at the time of admission to the academy, the prevalence of PFPS was not significantly different between genders.
YouTube as source of prostate cancer information.

Objectives Patients can search the Internet for prostate cancer information, and YouTube is a popular Web site that they may consult. We analyzed the prostate cancer videos on YouTube for information content and the presence of bias. Methods YouTube was searched for videos about prostate-specific antigen (PSA) testing, radiotherapy, and surgery for prostate cancer. The included videos were in English and Results A total of 14 PSA videos, 5 radiotherapy videos, and 32 surgery videos were analyzed. The PSA testing videos averaged 1480 ± 2196 views and 146 ± 174 s long and had an average viewer rating of 3.1 ± 2.1 (viewer rating scale 0-5). The surgery videos averaged 2044 ± 3740 views and 172 ± 122 s long and had an average viewer rating of scored 3 ± 2.2. The radiotherapy videos averaged 287 ± 255 views and 97 ± 45 s long and had a score of 1.8 ± 2.5. The information content was fair or poor for 73% of all videos. The bias for surgery, radiotherapy, or PSA testing was present in 69% of videos; 0% of videos were biased against treatment or PSA testing. The interobserver variability was well above than expected by chance alone. Conclusions The results of our study have shown that although some videos are robust sources of information, given the preponderance of modest and unbalanced information among reviewed videos, YouTube is an inadequate source of prostate cancer information for patients.
Modeling and Enhancing Android’s Permission System

Several works have recently shown that Android’s security architecture cannot prevent many undesired behaviors that compromise the integrity of applications and the privacy of their data. This paper makes two main contributions to the body of research on Android security: first, it develops a formal framework for analyzing Android-style security mechanisms; and, second, it describes the design and implementation of Sorbet, an enforcement system that enables developers to use permissions to specify secrecy and integrity policies. Our formal framework is composed of an abstract model with several specific instantiations. The model enables us to formally define some desired security properties, which we can prove hold on Sorbet but not on Android. We implement Sorbet on top of Android 2.3.7, test it on a Nexus S phone, and demonstrate its usefulness through a case study.
Dynamics of Metastable Nanoscale Island Growth and Dissolution at Electrochemical Interfaces by Time-Resolved Scanning Tunneling Microscopy †

The dynamics of nanoscale island growth, stability, and dissolution, accompanying the potential-induced phase transitions between the (22 × 3) and (1 × 1) structures of the Au(111) surface in 0.1 M HClO4 solution, have been investigated by potential pulse perturbation time-resolved scanning tunneling microscopy (P3 TR-STM). Starting from a potential at which the reconstructed (22 × 3) phase is stable, a short positive potential pulse briefly brings the electrode to a potential at which the (1 × 1) phase is stable. This pulse induces a perturbation that lifts the Au(111)−(22 × 3) reconstruction completely, resulting in nanoscale island formation on the surface. The nanoscale islands are metastable and dissolve with time. The initial average island area and the island decay rate are related to the pulse amplitude and duration. The higher and longer the pulse, the smaller the average size of the islands produced and the more slowly the islands decay. This result reveals a “voltammetric annealing” process tha...
A 2.4GHz non-contact biosensor system for continuous vital-signs monitoring

A non-contact vital-signs monitoring sensor system has been designed and tested. The system is assembled using two antennas instead of using one antenna and a circulator to achieve improved data accuracy with reduced DC offset. The system has been realized using a custom-designed analog baseband signal processing PCB that successfully replaces bulky baseband electronic blocks for system miniaturization. The sensor system was implemented in both single-channel and quadrature receiver configurations with the received signal being demodulated using several different algorithms. The vital-signs data extracted from a quadrature receiver with arctangent demodulation and autocorrelation method is found to be most accurate and reliable, achieving a mean error of +/- 1 beats/min vs. the reference heartbeat signal.
Failure of the Wiedemann-Franz law in mesoscopic conductors

We study the effect of mesoscopic fluctuations on the validity of the Wiedemannn-Franz WF law for quasi-one-dimensional metal wires and open quantum dots. At temperatures much less than the generalized Thouless energy, Ec, the WF law is satisfied for each specific sample, but as the temperature is raised through Ec, a sample-specific correction to the WF law of order 1/g appears g is the dimensionless conductance and then tends to zero again at kBTEc. The mesoscopic violation of the Weidemann-Franz law is even more pronounced in a ring geometry for which the Lorenz number exhibits h/e flux-periodic Aharonov-Bohm oscillations.
Aerosol Optical Properties and Particle Size Distributions on the East Coast of the United States Derived from Airborne In Situ and Remote Sensing Measurements

Abstract Airborne in situ measurements of vertical profiles and horizontal transects of aerosol optical and physical properties, obtained during the Chesapeake Lighthouse and Aircraft Measurements for Satellites (CLAMS) field campaign off the East Coast of the United States during the summer of 2001, are presented. Most of the measurements were obtained in relatively clean air dominated by airflows that had passed over Canada and the northern Atlantic Ocean. Results from the 17 July and 2 August 2001 flights are presented; on these days, the aerosol loading was relatively high. In the lower troposphere, ω0 values at a wavelength of 550 nm were consistently above 0.93 throughout the field experiment, indicating the dominance of weakly absorbing aerosol. Particle number size distributions are presented and discussed for transects at altitudes ∼0.05–3.5 km above mean sea level. Particles with diameters (Dp) <0.1 μm made up the majority of the aerosol number. Accumulation mode particles dominate the number si...
Test Input Generation Using UML Sequence and State Machines Models

We propose a novel testing approach that combines information from UML sequence models and state machine models. Current approaches that rely solely on sequence models do not consider the effects of the message path under test on the states of the participating objects. Dinh-Trong et al. proposed an approach to test input generation using information from class and sequence models.We extend their Variable Assignment Graph (VAG) based approach to include information from state machine models. The extended VAG (EVAG) produces multiple execution paths representing the effects of the messages on the states of their target objects.We performed mutation analysis on the implementation of a video store system to demonstrate that our test inputs are more effective than those that cover only sequence diagram paths.
Uterine secretion of prostaglandin F2 alpha in response to oxytocin in ewes: changes during the estrous cycle and early pregnancy.

Experiment 1 was conducted to determine when the ovine uterus develops the ability to secrete prostaglandin F,,, (PGF,,,) in response to oxytocin and how development is affected by pregnancy. Pregnant and nonpregnant ewes received an injection of oxytocin (10 IU, i.v.) on Day 10, 13, or 16 postestrus. Jugular venous blood samples were collected for 2 h after injection for quantification of 1 3,14-dihydro-1 5-keto-PGF,,. (PGFM). In nonpregnant ewes, concentrations of PGFM increased following oxytocin on Day 16 but not on Day 10 or 13. Concentrations of PGFM did not increase following treatment on Day 10, 13, or 16 in pregnant ewes. Therefore, the ability of oxytocin to induce uterine secretion of PGF,,, develops after Day 13 in nonpregnant but not in pregnant ewes. Experiment 2 was conducted to precisely define when uterine secretory responsiveness to oxytocin develops. Pregnant and nonpregnant ewes received oxytocin on Day 12, 13, 14, or 15. In nonpregnant ewes, concentrations of PGFM increased following treatment on Days 14 and 15, but not earlier. Peripheral concentrations of progesterone showed that uterine secretory responsiveness to oxytocin developed prior to the onset of luteal regression. As in experiment 1, the increase in concentrations of PGFM following administration of oxytocin was much lower in pregnant than in nonpregnant ewes; however, some pregnant ewes did respond to oxytocin with an increase in PGFM. In experiment 3, pregnant ewes received an injection of oxytocin on Day 18, 24, or 30 postmating. Concentrations of PGFM increased following oxytocin on Days 18 and 24. The conceptus appears to delay and attenuate the development of uterine secretory responsiveness to oxytocin.
NONITERATIVE COUPLED-CLUSTER METHODS FOR EXCITED ELECTRONIC STATES

New classes of noniterative coupled-cluster (CC) methods, which improve the results of the standard equation-of-motion (EOM) and re- sponse CC calculations for excited states dominated by two-electron transi- tions and excited-state potential energy surfaces along bond breaking coor- dinates, are reviewed. All of the methods discussed in this article are derived from the method of moments of CC equations (MMCC) and all of them are characterized by the relatively low computer costs which are similar to those characterizing the popular ground-state CCSD(T) theory. Three types of approaches are discussed: (i) the externally corrected MMCC ap- proaches employing the configuration interaction and multi-reference per- turbation theory wave functions, (ii) the completely renormalized EOMCC methods, including their most recent extension to excited states of radicals and other open-shell systems, and (iii) the new classes of MMCC and com- pletely renormalized EOMCC theories employing the left eigenstates of the similarity-transformed Hamiltonian used in CC/EOMCC theory.
The New Society for Theriogenology Breeding Soundness Evaluation System

In 1993, The Society for Theriogenology published revised standards for breeding soundness evaluation of bulls. These revised standards replaced the old semen score format with minimum acceptable scores for scrotal circumference (varies with age), motility (30% or fair), and morphology (70%).
The Song of Songs and the editor of editors : on the implications of the Netziv's Rinah Shel Torah

Naftali Zvi Yehuda Berlin (the Netziv, 1816-1893) led the Volozhin Yeshiva, the premier rabbinic academy, from 1853 until 1892 when it closed. A Talmudic scholar, he was a staunch traditionalist who is frequently described as an ardent opponent of biblical criticism. Given that position, it is difficult to explain his comment on Song 1:1 in which he describes the canonical text as a collection of songs edited by Solomon but which includes portions composed by earlier biblical characters (some named, some anonymous). In so doing, he made a radical break with the general trend of Jewish exegesis which reads the Song as an allegory concerning the unfolding history of the relationship between God and the nation of Israel. Berlin's commentary should be understood as his attempt to mediate between tradition and modernity by offering his students a work that appropriated new modes of biblical scholarship and dressed them in classical Jewish garb.
L-arginine analogues inhibit aldosterone secretion in rats

L-Arginine analogues, e.g., NG-nitro-L-arginine methyl ester (L-NAME), increase arterial pressure and suppress renin release in the rat. On the basis of these observations, it was hypothesized that L-arginine analogues also would attenuate aldosterone secretion. This hypothesis was tested in anesthetized rats treated with L-NAME or NG-nitro-L-arginine (L-NNA, 185 mumol/kg ip). The aldosterone secretion rate, plasma renin activity, and adrenal blood flow were attenuated in rats treated with L-NAME and L-NNA compared with control animals. Similar experiments were performed in anephric rats to examine the effects of L-NAME on aldosterone secretion independent of the circulating reninangiotensin system. The administration of L-NAME reduced adrenal blood flow but failed to reduce aldosterone secretion in these anephric rats. Bilateral nephrectomy reduced plasma renin activity essentially to undetectable levels in these animals. In a third series of experiments, two groups of anephric rats were infused with angiotensin II (3 micrograms/kg body wt iv) to provide a stimulus for aldosterone secretion. Aldosterone secretion and adrenal blood flow were markedly reduced in angiotensin II-infused rats pretreated with L-NAME compared with the control anephric animals infused with angiotensin II. Overall these results suggest that L-arginine analogues attenuate aldosterone secretion by inhibiting the adrenal steroidogenic effects of endogenous or exogenous angiotensin II and/or by reducing plasma levels of renin/angiotensin.
President Barack Obama as Agenda Leader: Presidential Agenda-Setting on the Economy and Foreign Policy

We analyze President Obama‘s public relations efforts on the economy and foreign policy from January 2009 through May 2012. Specifically, we track the amount of attention given the economy and foreign policy in Obama‘s public speeches and remarks and assess the degree to which they impacted or responded to media coverage of the economy and public concern for and confidence in the economy at both a weekly and monthly level. Our findings suggest that the president‘s attention to the economy was largely responsive to shifts in media attention and public opinion on the economy. This was especially the case with regard to his attention to jobs and unemployment. However, Obama‘s public leadership efforts on the topics of debt and spending directly impacted media coverage and indirectly affected public opinion on the economy. Obama‘s public remarks on foreign policy were largely responsive to media coverage of foreign policy.
Forward to McKellar Paper

Among aficionados of behavioral archaeology, the "McKellar hypothesis" has come to describe a rather commonly observed regularity of cultural formation processes: the tendency of small artifacts to be discarded as primary refuse in activity areas. The first statement of this hypothesis, along with supporting evidence, appears in the accompanying article by Judith McKellar, an undergraduate student enrolled in "Archaeological Interpretation" at the University of Arizona in the spring of 1973. This brief exercise, one of several involving the use of modern material culture, required the student to observe and attempt to explain a distribution of artifacts. McKellar chose to investigate trash deposition on the campus of the University of Arizona.
Construction of Phylogenetic Trees By Pattern Recognition Procedures

The sequence of a protein can be graphed as a discrete function and a cross-correlation between any two such number sets produces a similarity score. The scores are used to prepare a phylogenetic tree involving hierarchical cluster analysis, non-linear mapping, and minimal spanning routines. Changes are suggested in the sequences of cytochrome c’s from Mediterranean fruit fly, locust, and rattlesnake. The method is faster than existing procedures and does not require human intervention at any stage.
Continuous cultivation of epithelial cell strain (FL) from human amniotic membrane.

SummaryA strain of human cells derived from a normal amniotic membrane has been cultivated in serial passage for 8 months in 30 transfers. This cell line was developed by trypsinization of the primary source and cultivated in a medium without embryo extract. The appearance of the cell has been epithelial-like at all stages of cultivation. Growth characteristics in media containing human serum or animal sera are reported. The cell strain has been grown in large scale.
Spectrophotometric Estimation of Emtricitabine and Tenofovir Disoproxil Fumarate in Tablet Dosage form by Simultaneous Equation and Absorbance Ratio Methods

Two methods for simultaneous determination of Emtricitabine and Tenofovir Disoproxil Fumarate by spectroscopy have been developed. First method is Simultaneous equation method and second method is Absorbance ratio Method. From a solvent effect studies and the spectral behaviours of Emtricitabine and Tenofovir Disoproxil Fumarate, methanol was selected as solvent. Emtricitabine shows maximum absorbance at 281 nm and Tenofovir Disoproxil Fumarate shows maximum absorbance at 259 nm. Linearity in concentration range of 6-48 μg/mL and 4-32 μg/ mL was shown for Tenofovir Disoproxil Fumarate and Emtricitabine, respectively. In the first method, the concentration of the drugs were determined by using simultaneous equation and in second method the concentration of drugs were determined by using ratio of absorbances at isoabsorptive point and at the emax of one of the drug. The results of analysis were validated statistically and by recovery studies. Tablet containing both drugs was assayed using the methods developed, showing a good accuracy and precision.
On the Theory of Impurity States in Semiconductors

In this paper we first discuss the effective-mass concept in the theory of impurity states in semiconductors. We show that one cannot be justified in replacing m by the free-electron mass mo for either shallow or deep levels. Instead, we show that rigorous calculations may be interpreted in terms of an effective mass which is either smaller than m* or negative, but not equal to mo. Finally, we report results of new calculations of binding energies using model potentials and compare with our previous results obtained with first-principles pseudopotentials.
A Cr3+ luminescence study of spodumene at high pressures: Effects of site geometry, a phase transition, and a level-crossing

Cr 3+ luminescence of the green Cr-bearing variety of spodumene (LiAlSi 2 O 6 ) has been studied under hydrostatic conditions up to ~15 GPa. R-line luminescence is a particularly sensitive site-specific probe of the Al-site, and high-pressure phase transitions that affect the symmetry or electron density at this site should produce obvious changes in the luminescence spectra. Thus, the nature of Cr 3+ luminescence is probed across known and possible phase transitions in spodumene. Discontinuous shifts of the R-lines and their sidebands to higher energy at 3.2 GPa are associated with the C 2/ c to P 2 1 / c phase transition. Both R-lines and sidebands shift to lower energy after the 3.2 GPa transition up to ~15 GPa. The C 2/ c to P 2 1 / c phase transition is confirmed to be first order in nature based on its observed hysteresis on decompression, and R-line and sideband measurements give no evidence of a second proposed transition up to ~15 GPa. The splitting between the R 1 and R 2 bands is dramatically enhanced by pressure, with the split decreasing at the phase transition. These trends correspond to pressure-induced shifts in the distortion of the M1 site, and a likely shift in off-centeredness of the Cr 3+ ion. Pressure-induced decreases in line widths are consistent with the R-lines shifting at slower rates than the phonons to which they are most closely coupled, as demonstrated by large pressure shifts of vibronic peaks. Observations of a pressure-induced cross-over between the 4 T 2 and 2 E levels of the Cr 3+ ion indicate that spodumene undergoes a shift from an intermediate strength crystal field environment to a high strength crystal field environment at pressures between ambient and 3.2 GPa.
Noninvasive In Vivo Characterization of Pediatric Human Spine: 3-D Finite Element Study

There are no full three-dimensional computational models of the pediatric spine to study the many diseases and disorders that afflict the immature spine using finite element analysis. To fully characterize the pediatric spine, we created a pediatric specific computational model of C1-L5 using noninvasive in vivo techniques to incorporate the differences between the adult and pediatric spines: un-fused vertebrae, lax ligaments, and higher water content in the intervertebral discs. Muscle follower loads were included in the model to simulate muscle activation for five muscles involved in spine stabilization. This paper is the first pediatric three-dimensional model developed to date. Due to a lack of experimental pediatric spinal studies, this 3-D computational model has the potential to become a surgical tool to ensure that the most appropriate technique is chosen for treating pediatric spinal dysfunctions such as congenital abnormalities, idiopathic scoliosis, and vertebral fractures.© 2011 ASME
Abstract 3644: Identification of existing targeted agents that inhibit NTRK and ROS1 in lung cancer

All patients with oncogenic driver mutations in non-small cell lung cancer (NSCLC) who are treated with a targeted agent will eventually develop resistance. In an effort to identify inhibitors of NTRK1 and ROS1, which are inappropriately activated in NSCLC, we created and screened a library of existing targeted drugs against BaF3 cells transformed with these oncogenes. This screen identified the FDA-approved drug cabozantinib as a potent inhibitor of CD74-ROS1 (IC50 = 9 nM), including the crizotinib-resistant mutants G2032R (IC50 = 26 nM) and L2026M (IC50 = 11 nM), with no inhibition of the parental BaF3 cells (IC50 > 10 μM). AP26113, a dual ALK/EGFR inhibitor undergoing phase I/II clinical trials, also potently inhibited CD74-ROS1 (IC50 = 4 nM), including the crizotinib-resistant mutants G2032R (IC50 = 206 nM) and L2026M (IC50 = 84 nM), with weak inhibition of the parental BaF3 cells (IC50 > 1 μM). Both cabozantinib and AP26113 inhibited ROS1 autophosphorylation and downstream ERK activation in CD74-ROS transformed BaF3 cells and in the ROS1-rearranged NSCLC cell line HCC78. The FGFR3 inhibitor dovitinib, which is in phase III clinical trials for renal cell carcinoma, potently inhibited NTRK1 compared to parental BaF3 cells (IC50 = 69 nM vs > 1 μM), and blocked NTRK1 autophosphorylation and ERK activation. While acquired resistance to targeted therapies is a major clinical problem, this study highlights other existing agents that may overcome resistance, and identifies several promising candidates for clinical trials. Citation Format: Curtis Chong, Dalia Ercan, Magda Bahcall, Marzia Capelletti, Nathanael Gray, Pasi Janne. Identification of existing targeted agents that inhibit NTRK and ROS1 in lung cancer. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 3644. doi:10.1158/1538-7445.AM2015-3644
Effectiveness of the World Health Organization cancer pain relief guidelines: an integrative review

Inadequate cancer pain relief has been documented extensively across historical records. In response, in 1986, the World Health Organization (WHO) developed guidelines for cancer pain treatment. The purpose of this paper is to disseminate the results of a comprehensive, integrative review of studies that evaluate the effectiveness of the WHO guidelines. Studies were included if they: 1) identified patients treated with the guidelines, 2) evaluated self-reported pain, 3) identified instruments used, 4) provided data documenting pain relief, and 5) were written in English. Studies were coded for duration of treatment, definition of pain relief, instruments used, findings related to pain intensity or relief, and whether measures were used other than the WHO analgesic ladder. Twenty-five studies published since 1987 met the inclusion criteria. Evidence indicates 20%-100% of patients with cancer pain can be provided pain relief with the use of the WHO guidelines - while considering their status of treatment or end-of-life care. Due to multiple limitations in included studies, analysis was limited to descriptions. Future research to examine the effectiveness of the WHO guidelines needs to consider recommendations to facilitate study comparisons by standardizing outcome measures. Recent studies have reported that patients with cancer experience pain at moderate or greater levels. The WHO guidelines reflect the knowledge and effectual methods to relieve most cancer pain, but the guidelines are not being adequately employed. Part of the explanation for the lack of adoption of the WHO guidelines is that they may be considered outdated by many because they are not specific to the pharmacological and interventional options used in contemporary pain management practices. The conundrum of updating the WHO guidelines is to encompass the latest pharmacological and interventional innovations while maintaining its original simplicity.