cssi/SciSciGPT-SciSciNet huggingface dataset:
Business Librarians: Their Education and Training.

Subject expertise has been regarded as an important contributing factor in determining the quality of information services provided in specialized academic libraries. A telephone survey of academic business librarians was conducted to ascertain their level of business education. A survey of instructors of business information courses in library schools was conducted to discover the areas of business considered important in their courses. Results show that a minority of academic business librarians have been educated in business administration. Broad areas of business are considered important for library school course, but specialized and technical areas are considered less important. These results suggest that traditional education and training for business librarians are less than adequate. Partnerships between schools of business and schools of library and information science are suggested as one way to improve levels of business education for business information specialists.
Outcomes of radical cystectomy in potential candidates for bladder preservation therapy.

Objective To analyze the outcomes of patients with urothelial-type bladder cancer (UBC) who optimally met selection criteria for bladder preservation therapy (BPT) but were treated with radical cystectomy (RC) instead. Methods We identified consecutive patients with clinical stage cT2N0M0 UBC who underwent RC with curative intent at our center. Patients without carcinoma in situ, hydronephrosis, multifocality, or mixed histology were classified as BPT eligible. Patients with ≥1 contraindications were considered BPT ineligible. Clinicopathologic characteristics and survival outcomes for BPT-eligible patients were compared with those of the ineligible patients. Results Of the 275 patients who had cT2N0M0 UBC, 157 (57.1%) were BPT ineligible (carcinoma in situ = 54; hydronephrosis = 77; multifocality = 29; mixed histology = 55; ≥2 contraindications = 51). BPT-eligible and -ineligible patients did not statistically differ with regard to age, sex, race, or neoadjuvant chemotherapy. Of the BPT-eligible patients, 24.1% had occult positive lymph nodes and 36.4% had pT3 or pT4 tumors at RC. On multivariate analysis, mixed histology (odds ratio = 3.18; 95% confidence interval [CI], 1.18-8.56) and progression from noninvasive disease to cT2 (odds ratio = 4.81 [95% CI, 1.67-13.85]) were independently associated with upstaging. Two-year overall survival was higher in BPT-eligible patients (76.7% vs 57.1%; P = .003; hazard ratio = 0.48 [95% CI, 0.3-0.78]). BPT-eligible patients also had better cancer-specific mortality on competing risk analysis (sub-hazard ratio = 0.46 [95% CI = 0.29-0.72]; P = .001). Conclusion Substantial clinicopathologic stage discrepancies occurred even in patients seemingly ideal for BPT, which may provide insight into BPT failures. Furthermore, substantial survival discrepancies existed for BPT-eligible and BPT-ineligible patients, underscoring the heterogeneity of cT2 disease. In the absence of randomized trials, comparisons between RC and BPT must factor in selection bias.
An Extended Finite Element Method for Two-Phase Fluids

An extended finite element method with arbitrary interior discontinuous gradients is applied to two-phase immiscible flow problems. The discontinuity in the derivative of the velocity field is introduced by an enrichment with an extended basis whose gradient is discontinuous across the interface. Therefore, the finite element approximation can capture the discontinuities at the interface without requiring the mesh to conform to the interface, eliminating the need for remeshing. The equations for incompressible flow are solved by a fractional step method where the advection terms are stabilized by a characteristic Galerkin method. The phase interfaces are tracked by level set functions which are discretized by the same finite element mesh and are updated via a stabilized conservation law. The method is demonstrated in several examples
Sweet's syndrome in a patient with Crohn's disease: a case report

Sweet's syndrome, also known as acute febrile neutrophilic dermatosis, has been associated with malignancy, autoimmune disease and collagen vascular disease. The association of Crohn's disease and Sweet's syndrome is rare. We report a case of Sweet's syndrome in a patient with Crohn's disease. A 63-year-old man with a history of Crohn's disease presented with one-week duration of abdominal pain, diarrhea and hematochezia. He also noticed eruption of painful skin rashes all over his body at the same time. Colonoscopy and esophagogastroduodenoscopy (EGD) showed inflammation involving different parts of the gastrointestinal tract consistent with Crohn's disease. Punch biopsy of the skin lesion was consistent with Sweet's syndrome, which has a rare association with Crohn's disease. Crohn's disease should be excluded in patients presenting with Sweet's syndrome and diarrhea. Alternatively, Sweet's syndrome should be considered as a diagnosis when a patient with Crohn's disease develops skin lesions.
Occupant Protection as a Priority in National Efforts to Promote Health

Motor vehicle accidents are the leading cause of death for Americans ages 1 to 34 and cost our nation almost 57 billion dollars a year. Fortunately, many of the fatalities and serious injuries in motor vehicle accidents are preventable through proper and consistent safety belt and child safety seat use. Surprisingly, 80% to 90% of Americans rarely use safety belts, clearly making this one of the most significant public health problems. Increasing awareness of the importance of, and potential solution for this problem has led to integrating issues about motor vehicle trauma prevention into today's public health agenda. Efforts by federal health agencies are beginning to impact motor vehicle trauma reduction, but the involvement of public health workers at all levels is necessary for success.
Challenges and opportunities in engineered retrofits of buildings for improved energy efficiency and habitability

n contrast to almost every other artifact produced bymodern industrial society, (automobiles, jet aircraft,locomotives, ocean going vessels, etc.) the design,construction and operation of buildings is still highly frag-mented and comparatively unsophisticated. This is thecase even though the construction industry amounts toover one trillion dollars of the US economy. Materials ofconstruction, coatings, cladding, as well as electrical,mechanical and other components (windows, rooﬁng,heating, ventilation, air conditioning etc.) may be selectedindependently with little, or no, thought given to theirinteractions and the effects of their coupling on the build-ing’s performance. For some architects and building own-ers, especially of high-end structures for urban ofﬁcespace, the principal goal of design has often been visualimpact, which is to say that form dominates function.This kind of architectural statement is accomplished onlywith enormous up-front capital investments and with hugepenalties in downstream operating costs due to low efﬁ-ciencies inherent to the design. To say that energy efﬁ-ciency suffers most in such buildings is an understatement.The ﬁnancial model in such cases is that the architecturalstatement will be afforded with collection of very highrents. In some cases, little or no consideration is or waspaid to the habitability of the space in other words thebuilding’s indoor ecology was at best of secondary impor-tance.There are notable examples of such extravagant buildingsin almost every large American city, as well as around theworld; they are not hard to ﬁnd, but they are emblematic of aby-gone era. These buildings, constructed in the 20th century,symbolize much of what must be changed in the 21st centurybuilding industry; functionality and performance must trumpexcesses of form. As evidence that the society’s view of thesebuildings and buildings in general is changing rapidly, thepremier icon of the ‘‘sky-scraper era’’, the Empire StateBuilding, has undergone a deep retroﬁt to bring its efﬁciencyto the level of LEED Gold and this symbolizes the new stand-ards that can be achieved for older commercial buildings aswe move further into the 21st century
Underwater acoustic sensor networks: research challenges

Underwater sensor nodes will find applications in oceanographic data collection, pollution monitoring, offshore exploration, disaster prevention, assisted navigation and tactical surveillance applications. Moreover, unmanned or autonomous underwater vehicles (UUVs, AUVs), equipped with sensors, will enable the exploration of natural undersea resources and gathering of scientific data in collaborative monitoring missions. Underwater acoustic networking is the enabling technology for these applications. Underwater networks consist of a variable number of sensors and vehicles that are deployed to perform collaborative monitoring tasks over a given area. In this paper, several fundamental key aspects of underwater acoustic communications are investigated. Different architectures for two-dimensional and three-dimensional underwater sensor networks are discussed, and the characteristics of the underwater channel are detailed. The main challenges for the development of efficient networking solutions posed by the underwater environment are detailed and a cross-layer approach to the integration of all communication functionalities is suggested. Furthermore, open research issues are discussed and possible solution approaches are outlined. � 2005 Published by Elsevier B.V.
Rfc5p regulates alternate RFC complex functions in sister chromatid pairing reactions in budding yeast.

Sister chromatid pairing reactions, termed cohesion establishment, occur during S phase and appear to be regulated by replication factor C (RFC) complexes. For instance, RFCs that contain Ctf18p exhibit pro-establishment activities while those that contain Elg1p exhibit anti-establishment activities. It remains unknown whether Ctf18p-RFC and Elg1p-RFC functions are simply opposing or instead reveal complicated and non-parallel regulatory mechanisms. To better understand the nature of these novel pathways, we analyzed the small RFC subunit Rfc5p that is common to both Ctf18p-RFC and Elg1p-RFC. Despite this commonality, the data show that diminished Rfc5p function rescues ctf7/eco1 mutant cell phenotypes, revealing that Rfc5p promotes anti-establishment activities. This rescue is specific to establishment pathways in that rfc5-1 greatly accentuates growth defects when expressed in scc2 (deposition), mcd1/scc1 or smc3 (cohesion maintenance) mutated cells. Our results reveal for the first time a role for small RFC subunits in directing RFC complex functions—in this case towards anti-establishment pathways. We further report that Pds5p exhibits both establishment and anti-establishment functions in cohesion. This duality suggests that categorizations of establishment and anti-establishment activities require further examination.
Electrocardiographic and vectorcardiographic changes following surgery in persistent common atrioventricular canal.

Abstract The electrocardiogram and vectorcardiogram are probably the most reliable tools in the diagnosis of atrioventricular cushion defects. Our observations require further evaluation. Evidence has been offered suggesting that the electrocardiogram and vectorcardiogram also may assist in the evaluation of the effectiveness of surgical repair. It appears that there is enough evidence to conclude that the electrocardiographic and vectorcardiographic patterns observed in atrioventricular cushion defects are due not only to a congenital aberration of the left bundle but also to cardiac enlargement.
Differentiation of the microfilariae of Dirofilaria immitis and Dirofilaria repens in stained blood films.

Abstract: An examination was made of Giemsa-stained microfilariae in thin blood films from (n = 9) dogs naturally or experimentally infected with Dirofilaria immitis or Dirofilaria repens. Morphological measurements (total length, length of cephalic space, anterior end to nerve ring and last body nucleus, and nucleus-free tail tip) were made on 2–6 microfilariae from each dog with the use of digitally captured images and imaging software. The microfilariae of D. repens were significantly greater (P < 0.001) in all measured dimensions except for the length of the cephalic space, which was significantly shorter (P < 0.001) than that of D. immitis. The cephalic space of D. repens was characterized by being short and routinely being terminated by a distinct pair of nuclei that were separate from the remaining somatic nuclei of the microfilaria. The cephalic space of the smaller microfilaria of D. immitis was longer and did not have the distinct nuclei separated from the somatic column nuclei near the anterior...
Yield to Maturity Is Always Received as Promised: A Reply

This note attempts to further spell out why it is a myth that YTM is viewed as only a promised but not really earned interest rate. It addresses some misconceptions in Shirnani and Wilbratte (2009, this issue) on what, between YTM and RCY, is a true rate of return of a coupon bond, why YTM is NOT just a “fictitious mathematical construct”, and why YTM has nothing to do with yield curve.
Kimel and Garrett: Another Example of the Court Undervaluing Individual Sovereignty and Settled Expectations

Federal employment discrimination law has become the primary vehicle by which individuals pursue relief from discrimination in employment. For four decades federal legislation has provided a uniform system of rights and remedies, one that the Supreme Court has very recently fundamentally altered. Individuals have come to expect national protection from discrimination in employment based upon race, color, national origin, religion, sex, age, and disability, and there exists no good reason, constitutional or otherwise, for undermining this settled expectation for two sources of protection - disability and age. Certainly, a justification grounded in state sovereignty should not disturb these settled expectations around which people have ordered their lives. The need to exercise judicial restraint is especially critical when the Court is so bitterly yet so closely divided upon the issue of state sovereignty and when the legislation it thwarts prohibits the states in their capacity as employers from practicing invidious discrimination against individuals based upon traits or characteristics essentially unrelated to the ability to perform a job.
Hsi-Ping Liu(1944-2001)

Last spring, Hsi-Ping Liu, Russell Sell, and I (JBF) were visiting a seismograph site in the Hayward fault zone deploying one of an array of seismometers to study fault-zone guided waves. We were testing a set of 5-s seismometers that Hsi-Ping had modified to incorporate a novel leveling device. The device would automatically recenter the seismometers each day so that they would be stable for months to years. Hsi-Ping would put a small piece of paper on one of the masses, watch the mass drift for a few seconds, and then trigger the circuit to relevel the mass. It worked perfectly, as almost everything that Hsi-Ping engineered did. He gave it his ultimate compliment: “Better than in the lab.” Sadly, that turned out to be one of Hsi-Ping's last efforts, as he passed away recently after a short illness. He was a multitalented geophysicist who worked on both laboratory and field experiments as well as several purely theoretical problems. Although he had a quiet and reserved personality, he will be mostly remembered for his unusually kind and cooperative nature, which left his friends with a special feeling for the strength and goodness of the human spirit. Hsi-Ping was born in 1944 in Chungking, China during World War II. His family moved to Taiwan in 1949, where he grew up in far from prosperous circumstances. He graduated from Tunghai University in Taichung, Taiwan, majoring in physics. Although a quiet and reserved student, he was also bright and motivated. He was highly regarded among his classmates as someone who would make an important contribution to physics. But because of his love of mountains, Hsi-Ping changed his focus from physics to Earth science. He earned a Master's degree at Dartmouth College and then a Ph.D. at the California Institute of Technology. In the …
Control strategy requirements for connection of offshore windfarms using VSC-HVDC for frequency control

This paper focuses on the control schemes required on offshore VSC-HVDC networks to transmit the power to the onshore grid and provide fast frequency response for the AC grid. The simulation results show the benefits of such control scheme to restore the frequency in the grid after a loss of generation. The results further investigated the consequence of frequency disturbance in the islanded offshore windfarm and the capability of the VSC station to restore the frequency at the offshore point. (6 pages)
Initiation of DNA Synthesis in Primary Fetal Rat Hepatocytes in Culture

SummaryDNA synthesis can be initiated in quiescent fetal rat hepatocytes in culture by the addition of dialyzed fetal calf serum, arginine, or ornithine with a time course similar to the one observed after partial hepatectomy of the rat. A lag period of 14-16 hr was observed between the addition of the stimulus to the cultures and the onset of DNA synthesis. Cells are committed to synthesize DNA after incubation with serum for 12 hr. Serum or ornithine is active only when incubated in conditioned medium. It is suggested that DNA synthesis in cultured fetal rat hepatocytes is regulated by intracellular levels of arginine and/or ornithine and/or their proximal metabolites.We gratefully acknowledge the assistance of M. Henahan, B. Raspenti, J. Rippon, L. White, and M. Williams. The work was supported by research grants from the American Cancer Society, California Division, The Damon Runyon Memorial Fund for Cancer Research, Inc., and by the National Institutes of Health, U. S., Public Health Service.Note add...
IT-24DEVELOPMENT OF A NOVEL AUTOLOGOUS DENDRITIC CELL / ALLOGENEIC GLIOBLASTOMA LYSATE VACCINE PROTOCOL

BACKGROUND: Dendritic cell (DC) vaccines for glioblastoma (GBM) are promising but significant conceptual shortcomings may have limited their clinical efficacy. First, most trials have not employed optimal DC culture techniques resulting in large numbers of immature (immunosuppressive) DC's. Second, most have used autologous tumor lysate. While highly personalized, this limits vaccine availability and precludes antigen-specific response testing. Finally, GBM-mediated immunosuppression has been largely unaddressed. We have developed a novel DC vaccine protocol that addresses these issues. METHODS: The ability of standard DC culture techniques to produce mature (CD83+) DC's from healthy donors' and GBM patients' CD14+ monocytes was assessed. An optimized technique using GBM patients' monocytes was developed. A library of human Good Manufacturing Practices (GMP) GBM cell lines was established using a novel platelet lysate supplement. Immature/mature glioneuronal markers and tumor-associated antigens (TAA's) were assessed by western blot. Finally, multicolor FACS immunophenotyping of 120 leukocyte surface markers in 5mL whole blood was established. RESULTS: Standard culture techniques produce >90% mature (CD83+) DC's from healthy donor monocytes but 90% mature DC from GBM patients. Seven GMP-compatible GBM cell lines have been developed with clonigenic karyotypic abnormalities, immature (nestin) and some mature (GFAP, olig2, β-tubulin) glioneuronal marker expression, and expression of multiple TAA's. Our 120 marker panel produces comprehensive, reproducible immunophenotyping. CONCLUSION: We have developed a DC vaccination strategy that optimizes DC maturity, utilizes renewable GBM cell lines with established TAA expression profiles, and allows comprehensive immunophenotyping to identify responding/non-responding patient populations. Based on these studies, we have initiated a phase I clinical trial (MC1272; IND#15233) of autologous DC / allogeneic tumor lysate in newly diagnosed adult GBM patients that enables multiple vaccinations in most GBM patients with extensive immunophenotyping and TAA-specific response testing.
Effect of age on surface properties of excised lungs.

SummaryExcised lungs of human infants and 4 animal species were inflated and deflated at 2 to 8 cycles per minute. This resulted in a loss of stability of expansion in all adult and post-neonatal infant specimens tested, but was not true in neonatal lungs. It is suggested on the basis of available data that a qualitative as well as a quantitative difference exists between newborn and adult lungs in the surface active material of the alveolar lining layer. Intermediate stages have been observed in post-neonatal infant lungs of all species. Recovery of stability of expansion occurred at rest within a few minutes regardless of the state of expansion, or the use of air or nitrogen.
Application of Intelligent Motor Controller on Belt Conveyor in Thermal Power Plant

The influence of asynchronous motor's traditional starting or stopping manner on belt conveyor is introduced.The principle、feature and the application circumstance are also introduced emphatically.By using intelligent motor controller,the influence of motor's direct starting or stoppingmanner on belt conveyor has been solved.
Generation and Analysis of Ternary m Sequences Based on MATLAB

Multifocal-ERG is widely used in the clinical diagnosis of eye disease.Multifocal-ERG mainly through binary m-sequences to control the black and white graphics turned.Because the retinal nerve is sensitive to light of different colors,in order to obtain more information of the disease,it needs to research a multi-valued sequence to control the state of colors,so a three value m-sequence theory is proposed.Using the Matlab programming language its basic nature is simulated and analyzed.The simulation results show that the proposed three-m sequences have a very good correlation.It can distill the response signal from each stimulus spot very well by applying it in the multi-colored stimulation of Multifocus-ERG.
Biology of Mitochondrial ABCs and Their Contribution to Pathology

The mitochondria are key determinants in the life and death of a cell, and abnormalities in mitochondrial function are associated with a number of pathological conditions. Given that many crucial co-factors are generated in mitochondria, including heme and iron–sulfur clusters, it is a reasonable expectation that energy-dependent transporters might facilitate the efficient movement of these molecules through membrane barriers to their next enzymatic steps. The four mitochondrial ABC transporters are ABCB6, ABCB7, ABCB8, and ABCB10. Of these, ABCB6, ABCB7, and ABCB10 have been implicated in processes important to erythroid cells. Mitochondria are also the site of energy production, during which cytotoxic reactive oxygen species are generated. Through modulation of iron and heme biosynthesis, all four mitochondrial ABC transporters have important roles in protecting cells against excessive ROS. In humans, loss-of-function mutations in ABCB7 cause X-linked sideroblastic anemia with ataxia, and several variants that result in loss of ABCB6 at the surface of red cells have been used to identify a new blood group, Lan. ABCB8 has an important role in ischemia. Two of the mammalian mitochondrial transporters, ABCB6 and ABCB7, are closely related to homologs which serve to protect lower organisms from heavy metal toxicity, and mammalian ABCB6 has been demonstrated to provide resistance against some toxic metals, though the mechanism remains unclear. The physiology of mitochondrial transporters and how they contribute to pathological states will be discussed.
Two-Dimensional Difference Gel Electrophoresis (2D DIGE)

Abstract Two-dimensional difference gel electrophoresis (2D DIGE) is a modified form of 2D electrophoresis (2DE) that allows one to compare two or three protein samples simultaneously on the same gel. The proteins in each sample are covalently tagged with different color fluorescent dyes that are designed to have no effect on the relative migration of proteins during electrophoresis. Proteins that are common to the samples appear as “spots” with a fixed ratio of fluorescent signals, whereas proteins that differ between the samples have different fluorescence ratios. With the appropriate imaging system, DIGE is capable of reliably detecting as little as 0.2 fmol of protein, and protein differences down to ±15%, over an approximately 10,000-fold protein concentration range. DIGE combined with digital image analysis therefore greatly improves the statistical assessment of proteome variation. Here we describe a protocol for conducting DIGE experiments, which takes 2–3 days to complete.
Relative British and American Income Levels during the First Industrial Revolution

We provide new measures of relative UK and US GDP per capita and output per worker for the crucial years between 1830 and 1870. Our estimates are current price comparisons that compare expenditure on GDP for five benchmark years using new price data. They show that the US leads in income per capita and output per worker compared to Great Britain and the United Kingdom. We check our estimates against sectoral productivity data and real wages.
Calcitonin Receptor Agents

The calcitonin family of peptides, composed of calcitonin (CT), α-calcitonin gene-related peptide (αCGRP), βCGRP, amylin, adrenomedullin and intermedin, which is also known as adrenomedullin 2, elicit diverse biological actions including hypocalcemia, vasodilation, and reduction of food intake. CT receptors are family B (class II) G-protein coupled receptors (GPCR). CGRP receptors are composed of a heterodimeric complex between a similar family B GPCR called calcitonin receptor-like (CL) receptor and an accessory protein called receptor activity modifying protein 1 (RAMP1). Two other RAMPS’ exist called RAMP2 and RAMP3 that also associate with CL receptors to form adrenomedullin receptors, AM 1 and AM 2 , respectively. All three RAMP's associate with CT receptors yielding three amylin receptors named AMY 1 , AMY 2 , AMY 3 .
Systems Analysis in Water-Resources Investigations

Within the past decade, the planning and management of water-resource systems have been approached through the framework of systems analysis which is characterized by the interacting and complimentary roles of economics, engineering and hydrology. This approach has introduced new computational and mathematical techniques, involved in such procedures as optimization and simulation, into the water-resource field. Systems analysis of large- scale water-resource systems is based on mathematical models to extend the usefulness of existing data related to physical, chemical, biological, social and economic phenomena. The increasing use of systems analysis is linked closely to developments in the capabilities of high-speed, large-memory digital computers. Although systems analysis and computer applications are independent, computers are being used more extensively to assess larger ranges of feasible alternative schemes in the development of water resources.
Solar Protection Policy in School Children: Proposals for Progress

Children are especially susceptible to the deleterious effects of UV radiation, making childhood a critical period for a solar protection policy and its implementation. Sun-protective behaviors established early in life are likely to persist into adulthood. Limiting exposure to both artificial and natural UV radiation during childhood and adolescence lowers the risk for the development of skin cancer. A comprehensive approach to solar protection, including skill-based health education, supportive school environments, extensive family and community involvement, mass-media coverage, and sun-safety legislation, is essential. This chapter provides recommendations for sun protection in school children, discusses current controversies regarding sunscreen use and vitamin D deficiency, and summarizes current knowledge on pathophysiology, risk factors, as well as prevention of skin cancer.
Experimental determination of Representative Volume Element (RVE) size in woven composites

Abstract A systematic approach is proposed to estimate the length scales of the representative volume element (RVE) in orthogonal plain woven composites. The approach is based on experimental full-field deformation measurements at mesoscopic scales. Stereovision digital image correlation (DIC) is conducted to determine the full-field strain distribution in on- and off-axis specimens loaded axially in tension. A sensitivity analysis is carried out to optimize the image correlation parameters. Using the optimized set of image correlation parameters, full-field strains are measured and used in conjunction with a simple strain averaging algorithm to identify the length scales at which globally applied and spatially-averaged local strains converge in values. The size of a virtual window containing local strain data, the average of which has the same value as the global strain, is identified as the RVE dimensions for the examined material. The smallest RVE sizes found in this work are shown to be both strain and angle dependent. The largest RVE dimension obtained is reported as a unique, strain and orientation insensitive RVE size for the woven composite examined.
Managing inventories in multi-echelon on-line retail fulfillment system with different response lead time demands

When designing and operating an order fulfillment system for an on-line retailer, many factors must be taken into account. In this paper, we study a multi-echlon on-line fulfillment system with different response lead time demands. We present a delayed allocation system, which is called the primary warehouse system (PWS). In this system, inventories to satisfy different response lead time demands are managed differently. Since there are many millions of items managed in the system, determining stock levels quickly is a necessity. The focus of this paper is on planning inventory levels. Specifically, our goals are to describe a model for setting stock levels for each item, to present a computationally tractable method for determining their values, and to provide numerical results that illustrate the applications of the model to the on-line retailer's environment.
Service Learning in a Helping Skills Course

Dobbs-Oates begins discussion with defining service-learning and the positive outcomes of engaging in the practice. The author explores a service-learning project in an upper-division course for students majoring in Human Services at Purdue University entitled Skills for Helping Professionals in Individual, Family, and Group Settings. The project is designed as a multi-step, collaborative service-learning project. The author describes each phase in detail from team creation, developing a full proposal to carrying out the project and team/individual reflection. She follows discussion of the course design with discussion of each embedded high-impact element. She concludes with discussion about the fit of service learning with family sciences and the payoff of engaging in such practices.
Predictors of Adult Marijuana Use Among Parents and Nonparents.

The current study examined predictors of marijuana use among adults, including subsamples of adults who are actively parenting (i.e., have regular face-to-face contact with a child) and those who have no children. Participants were a community sample of 808 adults and two subsamples drawn from the full group: 383 adults who were actively parenting and 135 who had no children. Multilevel models examined predictors of marijuana use in these three groups from ages 27 to 39. Becoming a parent was associated with a decrease in marijuana use. Regular marijuana use in young adulthood (ages 21–24), partner marijuana use, and pro-marijuana attitudes increased the likelihood of past-year marijuana use among all participants. Being a primary caregiver (among parents) was associated with less marijuana use. Overall, predictors of marijuana use were similar for all adults, regardless of parenting status. Study results suggest that the onset of parenthood alone may be insufficient to reduce adult marijuana use. Instead, preventive intervention targets may include changing adult pro-marijuana attitudes and addressing marijuana use behaviors of live-in partners. Lastly, universal approaches targeting parents and nonparents may be effective for general adult samples.
Psychology Applied to Education

The status of psychology in the eighteenth century has not been fully determined; however, the beginning of psychology as applied to education probably goes back to Locke or Basedow 2 — or perhaps, more precisely, to the works of Pestalozzi before and after the turn of the eighteenth century.
Metastatic Sarcomatoid Squamous Cell Carcinoma of the Cervix Presenting with Chest Mass.

Background. Sarcomatoid squamous cell carcinoma is a rare and aggressive form of cervical cancer. We report a case of metastatic sarcomatoid squamous cell carcinoma (SSCC) of cervix that presented with an anterior chest wall mass. Case. A 43-year-old Hispanic female presented with a two-month history of a central chest wall mass. The patient’s only past medical history was SSCC of the cervix, stage IIB, diagnosed two years priorly. She underwent neoadjuvant chemoradiation therapy (CRT) with cisplatin followed by radical hysterectomy. Surgical margins were positive which led to adjuvant CRT with carboplatin and paclitaxel. PET scan 4 months after the postoperative treatment was negative for recurrence and metastatic disease. On current presentation, the CT chest revealed anterior mediastinal destructive soft tissue mass involving sternum, and the biopsy showed SSCC. The patient received palliative radiation therapy to her chest with improvement in pain and ability to swallow. After discussing the prognosis she refused further chemotherapy and decided on hospice care. Conclusion. Despite good response to first-line therapy, SSCC tends to recur early and does not respond to second-line therapy. Radiation therapy seems to be the most effective modality for treatment, but randomized controlled trials of therapy are impractical.
Mountain medical kits: epidemiology-based recommendations and analysis of medical supplies carried by mountain climbers in Colorado.

Objective : To provide medical kit recommendations for short mountain wilderness recreation trips (hiking, trekking, backpacking, mountaineering etc.) based on the epidemiology of injury and illness sustained and best treatment guidelines. Additionally, to compare these recommendations to the medical kit contents of mountain climbers in Colorado. Methods : A primary literature review concerning the epidemiology of injury and illness in mountain wilderness settings was performed. This information and literature on the efficacy of given treatments were used to derive recommendations for an evidence-based medical kit. The contents of 158 medical kits and the most likely demographics to carry them were compiled from surveys obtained from mountain climbers on 11 of Colorado's 14 000-foot peaks. Results : Musculoskeletal trauma, strains, sprains and skin wounds were the most common medical issues reported in the 11 studies, which met inclusion criteria. Adhesive bandages (Band-Aids) were the most common item and non-steroidal anti-inflammatory drugs were the most common medication carried in medical kits in Colorado. More than 100 distinct items were reported overall. Conclusion : Mountain climbing epidemiology and current clinical guidelines suggest that a basic mountain medical kit should include items for body substance isolation, materials for immobilization, pain medications, wound care supplies, and medications for gastrointestinal upset and flu-like illness. The medical kits of Colorado mountain climbers varied considerable and often lacked essential items such as medical gloves. This suggests a need for increased guidance. Similar methodology could be used to inform medical kits for other outdoor activities, mountain rescue personnel, and travel to areas with limited formal medical care.
Efficacy of Epidural Analgesia after Laparotomy in Children.

Background Epidural analgesia (EDA) is used as postoperative pain treatment in children, but little is known about its efficacy after laparotomy in children. This retrospective study investigated the efficacy of postoperative EDA after laparotomy in children and the frequencies of adverse effects and complications. Materials and Methods Data of all children aged 0 to 18 years undergoing laparotomy and treated with EDA in our hospital from January 2014 to December 2015 were collected. EDA was classified as successful either if the catheter was removed when there was no further need, and the patient was comfortable with oral/rectal analgesics or when EDA was continued after intervention. Results Ninety children with a median age of 3.7 years were included in the study. In 65% (59/90), EDA was classified as successful. In 34% (20/59) of all successful cases, an additional intervention was needed. In 35% (31/90), the catheter was removed earlier than planned, in half of these cases after an intervention. The primary reason for earlier removal was inadequate analgesia and technical failure. Adverse effects occurred in 18% and complications in 1% of cases. The successful group was significantly younger than the unsuccessful (p = 0.003). Conclusion EDA after laparotomy positively contributed to postoperative pain treatment in two-thirds of children. Numbers of adverse effects and complications were low. It is important to optimize pain management after laparotomy in children; thus, further prospective studies should focus on optimizing EDA and comparing EDA with other techniques of analgesia.
The Value of Freud's Illusion:

Freud wrote extensively regarding religion and his interpretation of the meaning of religious experience. Since Freud was a self-proclaimed atheist his writings have been largely ignored by the Chr...
Readiness to Change as a Predictor of Treatment Engagement and Outcome for Partner Violent Men

Resistance to change has been long recognized as a barrier to successful intervention for partner violent individuals. Using archival data from a community-based intimate partner violence (IPV) intervention program, the current study investigated readiness to change as a predictor of treatment engagement and outcome in cognitive behavioral therapy (CBT) for IPV, and examined whether court referral status, antisocial personality characteristics, and borderline personality characteristics moderate these associations. During program intake, male IPV perpetrators (N = 195) provided structured interview data on demographics and referral source, and self-report data on readiness to change, borderline personality traits, and antisocial personality traits. During group CBT, participants and their therapists completed measures of the working alliance, and the therapists completed ratings of compliance with behavior change homework assignments. Criminal recidivism data were gathered from public records for 2 years ...
Enhancement of effective linear RF surface resistance of superconducting surfaces by microscopic topography

Abstract Minimization of Radio-Frequency (RF) dissipation on superconducting surfaces is of interest for many applications. A prominent one is the use of Superconducting RF (SRF) cavities for charged particle acceleration . In addition to our previous investigation which characterized the occurrence of high-field non-linear losses by microscopic surface topography, the topic of increased linear losses as a function of surface topographic character merits consideration. Surfaces with isotropic homogeneous surface topography may be well characterized by power spectral density (PSD) derived from systematic height measurements. PSD characterizations of representative niobium cavity surface treatments have been developed: Electro-Polishing (EP), Nano-Mechanical Polishing (NMP) and Centrifugal Barrel Polishing (CBP) A perturbation model based on PSD statistical analysis is used to calculate additional RF loss on these surfaces when superconducting. The model assesses the penetration depth effects for a superconductor. We thus estimate the RF power dissipation ratio between these rough surfaces and an ideal smooth surface.
Implications of a Behavior Genetic Perspective in Behavioral Medicine

The contributors to this volume have provided detailed accounts of current behavior genetic research on alcoholism and smoking as examples of addictive behaviors, on cardiovascular parameters important to our understanding of stress responses, and on eating disorders and anthropometric indices related to obesity. While these topics are by no means exhaustive, they do provide central and substantive examples of behavior genetic research in behavioral medicine. Beyond this focus on specific phenotypes, our contributors have also considered the more general issues of gender differences in genetic and environmental influences and the relationship between behavior genetics and health-related research in minority populations.
LiCl perturbs ectodermal veg1 lineage allocations in Strongylocentrotus purpuratus embryos.

In normal development the veg_1 tier of the sixth cleavage Strongylocentrotus purpuratus embryo contributes progeny to both ectodermal lineages and portions of the archenteron. Treatment with 18 mM LiCl specifically affects this lineage allocation, reducing or eliminating the veg_1 contribution to ectoderm. Less frequently this concentration of lithium causes the progeny of animal blastomeres to contribute to the archenteron.
The epidemiology and ecology of blastomycosis, coccidioidomycosis and histoplasmosis.

Blastomycosis, coccidioidomycosis and histoplasmosis are the major pulmonary mycoses of humans. Each is considered to be a primary pulmonary disease acquired by inhalation of infectious spores from the environment. Blastomycosis occurs predominantly in the Mississippi River Valley and Southeastern portions of the U.S.A. Clinical cases have also been noted from a few other areas of the world. The etiologic agent, Blastomyces dermatitidis, is not readily recoverable from nature, but the disease is not contagious and must be acquired from some exogenous source poorly defined at present. Blastomycosis is common in dogs but unusual in other species although a wide variety of animals can be infected experimentally. The disease is more common in middle age, in blacks, and in males. Coccidioidomycosis is restricted to the Western Hemisphere where most cases occur in the semiarid regions of Southwestern U.S. and contiguous areas of Mexico. Limited endemic foci are found in South and Central American locations. The arthroconidia of Coccidioides immitis occur in the soil of endemic areas from whence they are inhaled by humans and other animals. The disease is not customarily contagious. Handling cultures in the laboratory is a serious biohazard. The basis for an apparent racial predisposition to develop disseminated disease is unknown. Two clinical entities distinguishable by their etiologic agents are recognized to comprise histoplasmosis. Histoplasmosis caused by Histoplasma capsulatum var. capsulatum is a cosmopolitan disease with the greatest known concentration of cases located in the eastern half of the U.S. and most of Latin America.(ABSTRACT TRUNCATED AT 250 WORDS)
Psychiatric Research in Mental Retardation

“Psychiatric” research in mental retardation may be defined from a number of viewpoints. Psychiatric might be taken to mean that the research has been performed by psychiatrists. Insofar as mental retardation is concerned, it could mean research performed by child psychiatrists, as they are much more likely (perhaps because they deal with development) to be concerned with mental retardation than is the general psychiatrist. Inasmuch as the child psychiatrist is broadly trained in biological issues, in child development, and in clinical assessment and treatment, it could be expected (even demanded of the profession as a whole) that child psychiatrists play a major role in research into the causes and treatment of serious psychopathology in childhood, including mental retardation.1 Project Future,2 an enterprise set in motion by the American Academy of Child Psychiatry, concluded in its final report (1983) that many more child psychiatrists must develop expertise in research, must become active in designing and carrying out research studies, and must provide leadership in child mental-health research. To this end, the report recommended that more training programs in child psychiatry provide research experience, and that postresidency research fellowships be made available to supplement such programs as the NIMH’s Research Scientist Development Awards.
Model Systems for Studying Adventitious Root Formation

Organogenesis involves a series of complex events, and the molecular mechanisms controlling organogenesis are not well understood in plant or animal systems. Apical meristems exert the greatest influence on organogenesis in plant development relative to other meristematic tissues, and are, therefore, important foci in studying plant development. The root apical meristem (primary, lateral and adventitious) is simpler in cellular composition compared to the shoot apical meristem, and therefore may be more amenable to genetic and developmental characterization relative to shoot apical meristems. However, the basic biology of de novo (adventitious) root apical meristem formation is still poorly understood, and will require a concerted effort in the scientific community to dissect the developmental events involved in the formation of this meristem (see the chapter by Barlow and by Haissig and Davis in this volume).
Urinary Polyamine Levels in the Diagnosis of Carcinoma of the Prostate

AbstractUrinary excretion of the basic polyamine, spermidine, was significantly elevated in patients with prostatic carcinoma as compared to a control group of patients. Of 44 urine specimens from patients with prostatic malignancy 31 had spermidine levels more than 2mg. per 24 hours, while only 3 of 13 urine specimens from the control groups had levels in excess of this value. The increase in spermidine appeared to be correlated with the histologic grading of the tumor, that is 30 of 34 specimens from patients with grade II, III or IV carcinoma had excessive spermidine excretion and only 1 of 10 urine specimens from patients with grade I tumors had similar spermidine elevations. High spermidine levels were found in tumors localized to the prostate and in 7 of 8 patients with negative pelvic and para-aortic lymph node biopsies. This study raises the possibility that urinary spermidine determinations may aid in the development of a biochemical screening test for prostatic neoplasms.
How Features of a Civic Design Competition Influences the Collective Understanding of a Problem

From Fortune 500 companies to local communities, organizations often strive to build a shared understanding about complex problems. Design competitions provide a compelling approach to create incentives and infrastructure for gathering insights about a problem-space. In this paper, we present an analysis of a two-month civic design competition focused on transportation challenges in a major US city. We examine how the event structure, discussion platform, and participant interactions affected how a community collectively discussed design constraints and proposals. Ninety-two participants took part in the competition's online discussion, hosted on Slack. Applying a mixed-methods analysis, we found that participants shared less as they settled into teams and, due to the discussion system, had difficulty seeing how topics connected across channels; we also learned that certain messages led participants to add depth to existing topics. Based on the findings we provide recommendations for civic competitions aimed at building knowledge around a problem.