cssi/SciSciGPT-SciSciNet huggingface dataset:
Egg parasitoids of Proconiini (Hemiptera: Cicadellidae) in northwestern Mexico, with description of a new species of Gonatocerus (Hymenoptera: Mymaridae).

Nine species of Mymaridae and Trichogrammatidae parasitic on eggs of Proconiini sharpshooters (Cicadellidae: Cicadellinae) were collected in northwestern Mexico in relation to neoclassical biological control efforts against glassy-winged sharpshooter, Homalodisca vitripennis (Germar), in California. Gonatocerus chula Triapitsyn and Bernal sp. n., which belongs to the ater species group of Gonatocerus Nees (Mymaridae), is described. Specimens of G. chula sp. n. were reared from eggs of the smoke-tree sharpshooter, Homalodisca liturata Ball, on jojoba [Simmondsia chinensis (Link) C. K. Schneider] leaves collected in central Sonora state, Mexico. Also given are new data on other egg parasitoids of Homalodisca spp. and Oncometopia spp. in Sinaloa and Sonora states, Mexico, including Gonatocerus atriclavus Girault, G. morrilli (Howard), and G. novifasciatus Girault, and the Trichogrammatidae Burksiella sp(p)., Ittys sp., Pseudoligosita sp., Ufens ceratus Owen, and U. principalis Owen. For the first time, a species of Ittys is recorded from eggs of Proconiini, and U. principalis from Mexico. Colonies of G. atriclavus, G. novifasciatus and Pseudoligosita sp. were successfully established in a quarantine laboratory at University of California, Riverside, on eggs of the glassy-winged sharpshooter. These three parasitoid species had never been reared under laboratory conditions. In addition, seven species of Proconiini were collected in central and northwestern Mexico: Cyrtodisca major (Signoret), Homalodisca insolita (Walker), H. liturata Ball, Oncometopia sp. cf. clarior (Walker), O. sp. cf. trilobata Melichar, O. (Similitopia) sp., and Phera centrolineata (Signoret). Oncometopia sp. cf. clarior, O. sp. cf. trilobata, and O. (Similitopia) sp. appeared to be undescribed species.
Correlations in underwater acoustic particle velocity and pressure channels

Depending on the angle of arrivals (AOAs) and other channel characteristics, different types of correlation appear among acoustic pressure and acoustic particle velocity channels. To have accurate channel models for communication system design, a complete set of correlations are derived in this paper for a vector sensor array. In addition to exact results, accurate yet less complex approximations are derived as well. Based on the exact correlations, delay spread of pressure and particle velocity channels are calculated as well.
Online survey of nursing journal peer reviewers: Indicators of quality in manuscripts

Nursing journal peer reviewers (N = 1,675) completed a 69-item online survey that assessed their views on manuscripts’ contributions to nursing, priorities in writing reviews, use of journal impact factor, and other areas related to indicators of quality. They reported using contribution to knowledge or research evidence, topic of current interest, and newly emerging area as indicators of a manuscript’s contribution to nursing. In writing their reviews, research rigor and clinical relevance of the manuscript were high priorities. Those familiar with the concept of impact factor were significantly more often not nurses; not United States residents; involved in research; and most often reviewed for journals that published only research or a scholarly mix of research, reviews, policy, and theory. When judging a paper’s contribution, nursing journal peer reviewers weigh both research and clinical interests. Most reviewers do not use impact factors and place clinical considerations ahead of impact factors.
Serological Distinction of Bovine Salmonella Carriers from Vaccinated and Acutely Infected Cows

Identification of Salmonella carriers using lipopolysaccharide (LPS) ELISA serology in a Salmonella-infected herd requires distinction of chronically infected cattle from convalescent and vaccinated cows. Cows responding to Salmonella infection and vaccination produce titers to Salmonella LPS that overlap with the lower titers of some Salmonella carriers. The objective of this study was to determine if the LPS antigen specificity of the bovine humoral immune response to Salmonella LPS antigens differs following vaccination and acute and chronic Salmonella infection. The study focused on the nondiscriminatory area of Salmonella ELISA serology, specifically, peak-titered sera from Salmonella bacterin-vaccinated and experimentally infected cows and low-titered sera from Salmonella carriers. The LPS serogroup specificity of the IgG1 and IgG2 response following acute and chronic Salmonella serotype Dublin infection and Salmonella bacterin vaccination was evaluated using 5 Salmonella serogroup (B, D, E1, C3, and C1) LPS ELISA assays. IgG, titers of carriers, vaccinated, and acutely infected cows were predominantly O antigen specific. Similarly, the IgG2 titers of acutely infected cows were also O antigen specific. In contrast, Salmonella carriers produced an IgG2 response to each of the heterologous LPS antigens (B, E1, C3, and C1) examined. The results of this study indicate that the bovine IgG1 isotype response to Salmonella LPS is serogroup specific. Conversely, production of IgG2 antibodies to core Salmonella LPS antigens shared across Salmonella serogroups is a feature of chronic Salmonella infections.
View from a Former Editor

The Schizophrenia Bulletin had its first experimental issue as the brainchild of Loren Mosher in 1969. Beginning modestly, as a vehicle to disseminate research from the National Institute of Mental Health—who knew at that pointthatgovernmentaldisseminationoffundedresearch would become controversial 35 years later. The Bulletin grew under Loren’s leadership and the editorial managementofSherryBuchsbaumandlaterBarbaraBrunertobe oneofthetopfivejournalsinbehavioralscienceinimpact factor rating. The first 14 issues were considered ‘‘experimental,’’butby1975theBulletinwenttofourissueseach year and developed a subscriber base through the governmentprintingoffice.Intheearly1980s,Ibecameeditorof the Bulletin followed in 1993 by David Shore and in 1999 by John Hsiao. There were many constants and many innovations presented in the Bulletin over the years. Among the constants that were readily visible and separated the Bulletin from many journals were the cover art by patients and the first-person accounts by patients and families describing the impact of the illness on their lives.ThroughoutthehistoryoftheBulletintheinnovative editorialphilosophyhadbeentogiveenoughspacetopresent significant findings in sufficient detail to fully inform the field. Toaddress controversialtopics—andthere were anumberofthem—leadingfiguresfrommanyviewpoints were invited to comment. Some of the most significant figures in our field played major roles in shaping the thinking that went into the pages of the Bulletin: Manfred Bleuler, Gerry Klerman, John Romano, John Strauss, Will Carpenter, Tom McGlashan, Norman Garmezy, IrvGottesman,JohnGunderson,SeymourKety,Richard
Asynchronous vascular consultation via electronic methods: A feasibility pilot

Management of chronic disease often requires multidisciplinary clinical efforts and specialist care. With the emergence of Accountable Care Organizations (ACOs), health care systems are incentivized to evaluate methods of information exchange between generalists and specialists in order to provide value while preserving quality. Our objective was to evaluate patient and referring provider satisfaction and outcomes of asynchronous electronic consultations in vascular care in a large tertiary academic medical center. Referring providers were offered a vascular 'e-consult' option through an electronic referral management system. We conducted chart review to understand the downstream effects and surveyed patients and referring providers to assess satisfaction. From 24 March 2014 to 1 March 2015, 54 e-consults were completed. Additional testing and recommendations were made in 49/54 (90.7%) e-consults, including lower-extremity venous duplex ultrasonography with reflux testing, duplex ultrasonography of the carotid artery, computed tomography, magnetic resonance imaging, non-invasive physiology arterial studies, laboratory tests, medications, compression stockings, and sequential lymphedema compression therapy. Referring providers were compliant with recommendations in 40/49 (81.6%) of e-consults. A total of 17/54 (31.5%) patients were surveyed with a median patient satisfaction score of 13.7/15 (91.3%) (SD ± 6.4). The program was associated with high referring provider satisfaction, with 87.0% finding the e-consult very helpful and 80.0% stating it averted the need for a traditional visit. Our experience suggests that e-consults are an effective way to provide vascular care in some patients and are associated with high patient and provider satisfaction. E-consults may therefore be an efficient method of care delivery for vascular patients within an ACO.
Live Cell Discovery of Microbial Vitamin Transport and Enzyme-Cofactor Interactions

The rapid completion of microbial genomes is inducing a conundrum in functional gene discovery. Novel methods are needed to shorten the gap between characterizing a microbial genome and experimentally validating bioinformatically predicted functions. Of particular importance are transport mechanisms, which shuttle nutrients such as B vitamins and metabolites across cell membranes and are required for the survival of microbes ranging from members of environmental microbial communities to pathogens. Methods to accurately assign function and specificity for a wide range of experimentally unidentified and/or predicted membrane-embedded transport proteins, along with characterization of intracellular enzyme-cofactor associations, are needed to enable a significantly improved understanding of microbial biochemistry and physiology, microbial interactions, and microbial responses to perturbations. Chemical probes derived from B vitamins B1, B2, and B7 have allowed us to experimentally address the aforementioned n...
Manganese in Total Parenteral Nutrition

Manganese is a trace element included in total parenteral nutrition therapy preparations in order to prevent development of deficiency symptoms such as nausea, vomiting, weight loss, dermatitis, and changes in growth and color of hair.
Transcendental Unity of Apperception and Its Necessity

As we saw in Chapter Six, (S) is the strong unity-of-apperception claim that all the elements of i are such that H is or can become conscious, in thought, that the I think accompanies all those elements taken together. Given the failure of our Chapter Six arguments for (S), it seems impossible for Kant to prove that i’s elements form a synthesis-established (and necessary) unity within H’s mind in a way that leads to category application to the object of i. So, also, he cannot generalize to the main, B-Deduction first-half conclusion that, necessarily, the object of any sensible intuition in general through which a being like us knows is subject to the categories. And hence in the second half of the B-Deduction he cannot apply that conclusion to the human a priori intuitions of space and time in such a way as to reach the final B-Deduction result that, necessarily, the object of any sensible, empirical intuition through which we know falls under the categories. Kant’s failure to demonstrate (S) thus abruptly halts the argument of the B-Deduction (and of the A-Deduction), and so we must decide how to proceed if something like the Deduction reasoning is to be maintained.
Protection of scaffold protein Isu from degradation by the Lon protease Pim1 as a component of Fe–S cluster biogenesis regulation

Iron-sulfur (Fe-S) clusters, essential protein cofactors, are assembled on the mitochondrial scaffold protein Isu and then transferred to recipient proteins via a multistep process in which Isu interacts sequentially with multiple protein factors. This pathway is in part regulated posttranslationally by modulation of the degradation of Isu, whose abundance increases >10-fold upon perturbation of the biogenesis process. We tested a model in which direct interaction with protein partners protects Isu from degradation by the mitochondrial Lon-type protease. Using purified components, we demonstrated that Isu is indeed a substrate of the Lon-type protease and that it is protected from degradation by Nfs1, the sulfur donor for Fe-S cluster assembly, as well as by Jac1, the J-protein Hsp70 cochaperone that functions in cluster transfer from Isu. Nfs1 and Jac1 variants known to be defective in interaction with Isu were also defective in protecting Isu from degradation. Furthermore, overproduction of Jac1 protected Isu from degradation in vivo, as did Nfs1. Taken together, our results lead to a model of dynamic interplay between a protease and protein factors throughout the Fe-S cluster assembly and transfer process, leading to up-regulation of Isu levels under conditions when Fe-S cluster biogenesis does not meet cellular demands.
What is the Probability that Two Group Elements Commute

(1973). What is the Probability that Two Group Elements Commute? The American Mathematical Monthly: Vol. 80, No. 9, pp. 1031-1034.
Encouraging Nonretirement Savings at Tax Time: Final Impact Findings from the SaveUSA Evaluation

SaveUSA encourages low- and moderate-income people to set aside money from their tax refund for savings by awarding a 50 percent match to successful savers. After 42 months, the program had sustained its earlier effects, increasing both the percentage of individuals with nonretirement savings and the average amount of savings.
Epidemic characteristics and influence factors of Japanese B Encephalitis in Xinyang and Luoyang in 2004-2010

To analyze the epidemic characteristics and influence factors of Japanese B Encephalitis(JE) in Xinyang and Luoyang of Henan Province,the epidemic situation information of JE in Xinyang and Luoyang from 2004 to 2010,the information of mosquitoes survey in 2 cities in 2010,and the information of healthy people′ antibodies in 2010 were all statistically analyzed by SPSS 12.0 and Excel 2003.JE neutralizing antibody was examining by using MCPENT.From 2004 to 2010,the annual average incidence rate of JE and the annual average mortality rate were 1.97/100,000 and 2.92% in Xinyang,and 1.01/100,000 and 9.73% in Luoyang.The 91.47% of total cases in Xinyang were occurred from July to August;84.29% of the total cases in Luoyang were occurred from August to September of 97.52% of patients in Xinyang were in 14-year-old group;57.08% of patients in Xinyang were in ≧ 15-year-old group.They had statistical significance.(χ2=557.71,P 0.05).Most patients were scattered children(68.36%) in Xinyang and farmers(46.46%) in Luoyang.The peak of mosquito density appeared from June to July in Xinyang,and the density was 25.09 per labor hour in June and 27.31 in July.The peak of mosquito density appeared from July to August in Luoyang,and the density was 13.94 per labor hour in July and 14.12 in August.The JE neutralizing antibody positive rate of ≧ 15-year-old age group was were 97.78% in Xinyang and 48.94% in Luoyang.They had statistical significance(χ2 =55.42,P0.05).The peak of incidence of JE in Xinyang was a month earlier than Luoyang and this was consistent with the peak of mosquito density.The primary patients were in 14-year-old group;in Xinyang,the primary patients were in ≧ 15-year-old group in Luoyang.This is consistent with the difference between the JE neutralizing antibody in 2 cities.Targeted prevention and control measures are the keys to reduce the incidence of JE.
Advances in somatic cell nuclear transfer: the selection of donor cell and recipient cell

This article is to review the latest development of nuclear transfer, mainly focusing on the selection of donor cell and recipient cell and the recombination of nucleus and oocyte. We hope that it will be helpful to the professional researchers in this field.
Indicators and Protocols for Monitoring Impacts of Formal and Informal Trails in Protected Areas

Trails are a common recreation infrastructure in protected areas and their conditions affect the quality of natural resources and visitor experiences. Various trail impact indicators and assessment protocols have been developed in support of monitoring programs, which are often used for management decision-making or as part of visitor capacity management frameworks. This paper reviews common indicators and assessment protocols for three types of trails, surfaced formal trails, unsurfaced formal trails, and informal (visitor-created) trails. Monitoring methods and selected data from three U.S. National Park Service units are presented to illustrate some common trail impact indicators and assessment options.
The Effects of a Supplemental Perceptual Training Program on Reading Achievement.

At the beginning of the first grade, 105 students designated as potential reading problems were divided into three groups of 35 children each: experimental I, which received supplementary perceptual training in addition to the regular reading program; experimental II, which received traditional supplementary reading instruction in addition to the regular reading program; and the control group, which received no supplementary instruction. The Metropolitan Achievement Test (MAT) was administered at the end of May. The statistical analysis of the data indicated that, of all the groups, only the experimental I total group and the experimental I boys read significantly better than the respective control groups on the reading subtest of the MAT.
Intersectionopoly: A Simulation of the Wage Gap

This article describes a simulation activity designed to teach students about the wage gap. The wage gap is an important topic in many sociology classrooms, but it can be difficult to convey the ac...
Partially Nonergodic Empirical Ground‐Motion Models for Predicting Horizontal and Vertical PGV, PGA, and 5% Damped Linear Acceleration Response Spectra Using Data from the Iranian Plateau

We present new ground‐motion prediction equations (GMPEs) to estimate horizontal and vertical strong ground motion intensity measures (GMIMs) generated by shallow active crustal earthquakes occurring within the Iranian plateau. To this end, a dataset containing 688 records from 152 earthquakes with moment magnitudes ranging from 4.7 to 7.4 and Joyner–Boore distances up to 250 km has been used. The effects of the local site condition are taken into account using the time‐averaged shear‐wave velocities in the upper 30 m ( V S 30). We decided not to include the style‐of‐faulting term in the final functional form because the total standard deviation is reduced 10% by removing this term from the functional form. We used a nonlinear mixed‐effects regression to determine the coefficients of the functional form and to separate out the between‐event and between‐station standard deviations from the total standard deviation. Significant standard deviation of site‐to‐site variability demonstrates that the ergodic assumption is not able to account for the spatial variability of ground motions. We introduced random‐effects coefficients to capture regional variations between different tectonic regions of the Iranian plateau, such as Alborz and Zagros, in the regression analysis to investigate the effects of regionalization on GMPEs. The results showed that, although the effects of regional variations for considered regions are negligible at close distances, they are significant at longer distances. The complexity and performance of the final functional form is justified by comparing Akaike and Bayesian information criteria values over many trial functional forms. Moreover, the distribution of between‐event, site‐to‐site, and event‐station corrected residuals demonstrates that no trends are evident, implying satisfactory performance of the proposed GMPEs. Therefore, the derived GMPEs can be employed to predict GMIMs and to do seismic‐hazard assessments within the Iranian plateau. [Electronic Supplement:][1] Lists of the events and stations considered in the final dataset and derived coefficients of the functional form. [1]: http://www.bssaonline.org/lookup/suppl/doi:10.1785/0120160205/-/DC1
Communities Leveraging the Assets of a National Social Marketing Campaign: Experiences with VERB™. It’s What You Do!

The VERB. It’s what you do! social marketing campaign used mass media, school and community promotions, the Internet, and partnerships with national organizations and local communities to encourage children aged 9–13 years (tweens) to be physically active every day. The national presence of VERB through paid advertising on multiple media outlets facilitated the penetration of the campaign into communities where tweens could sample the product of physical activity through multiple school and community promotions, tours, and events. Some communities responded by using the VERB brand to develop their own programs for physical activity, giving the local community activities the cachet and cool factor associated with the images the tweens were seeing in the national marketing campaign. This chapter focuses on the community presence of VERB that developed from the national media platform and through the community-generated programs that leveraged the assets of the VERB brand to bring physical activity opportunities to tweens in their own communities.
Phosphonium Salts as Pseudohalides: Regioselective Nickel-Catalyzed Cross-Coupling of Complex Pyridines and Diazines

Heterobiaryls are important pharmacophores that are challenging to prepare by traditional cross-coupling methods. An alternative approach is presented where pyridines and diazines are converted into heteroaryl phosphonium salts and coupled with aryl boronic acids. Nickel catalysts are unique for selective heteroaryl transfer, and the reaction has a broad substrate scope that includes complex pharmaceuticals. Phosphonium ions also display orthogonal reactivity in cross-couplings compared to halides, enabling chemoselective palladium- and nickel-catalyzed coupling sequences.
Profitability and efficiency evaluation of the financial management of a socio-economic intervention

The role of small businesses is critical in the growth of an economy, and in certain circumstances these necessitate financial aid for their sustainability. The main objective of the study is to evaluate the profitability and efficiency of the financial management of the intervention for the improvement of the socio-economic condition of the small businesses in Santol, La Union, Philippines. The article specifically addressed the functionality of the financial aid relative to the actions taken by the beneficiaries for their small businesses, the profitability and efficiency of financial management condition of the small businesses, and the impact on the socio-economic condition of the small business beneficiaries. The study utilized the descriptive type of research mixing qualitative and quantitative analysis by applying financial ratios. It covered the small businesses from three associations and their 127 members. It was found that the association-beneficiaries deposited the money in a bank before the loaning services. The small businesses became profitable and efficient in utilizing the financial aid. The overall socio-economic impact is good as reflected in the results of their financial management. The small businesses of the associations were able to continue operating and provided loaning services to their needy members. It is concluded that with close monitoring and evaluation, small businesses that were granted financial aid are profitable and efficient in their financial operations. It is then recommended that monitoring and evaluation as well as the provision of interventions for the small businesses be sustained to ensure contribution of small businesses to the economic growth of the society.
Phytochemicals as Anti-microbial Food Preservatives

Phytochemicals containing essential oils (EOs) in the range of 0.05–0.1% have demonstrated inhibitory activity against pathogens, such as Salmonella Typhimurium, Escherichia coli O157:H7, Listeria monocytogenes, Bacillus cereus and Staphylococcus aureus, in food systems. Three major limitations for the broad application of phytochemicals in food are: limited data about their effects in food, strong odor, and high cost. New techniques and synergistic effect of compounds have been successfully applied in several food and in-vitro experiments. Several in-food and in-vitro applications of essential oils, phenolic and other components are discussed in this chapter.
Reprint of: Clinical management of tardive dyskinesia: Five steps to success

Tardive dyskinesia (TD) has long been thought to be a generally irreversible consequence of the use of dopamine receptor blocking agents. There is now an opportunity to successfully manage this condition with agents approved by the US Food and Drug Administration. This is important because TD has not been eliminated with the use of second-generation antipsychotics, and the expansion of antipsychotics to treat conditions other than schizophrenia has resulted in millions of additional individuals at risk for developing TD. Recognition of TD requires careful observation; a structured approach using the Abnormal Involuntary Movement Scale is encouraged. Harm reduction can be achieved by using antipsychotics judiciously when possible and by paying attention to other modifiable risk factors such as drug-induced parkinsonian symptoms and the use of anticholinergic medication. Once TD has emerged and is associated with dysfunction or distress, treatment with a VMAT2 inhibitor such as deutetrabenazine or valbenazine is well supported by several controlled clinical trials.
Rice Seed Development: Highly Resolved Transcriptomic Views

Rice is an experimental model for monocot grain crop biology. Its seeds provide a major portion of the diets of many human cultures. Recently, microarray and RNA-sequencing methods have produced highly resolved genome-wide inventories of RNA transcripts present in cell types and regions of rice seeds, including the development of embryo and endosperm tissues and the changes that accompany germination. This chapter describes these rice seed transcriptome inventories and highlights the novel biological insights that they provide regarding the regional specialization of biological processes in endosperm and embryo. The spatial and temporal patterns of expressed genes support some of the anatomical homologies that have long been proposed for regions of the monocot embryo and endosperm.
Can Suspicious Ultrasound Features Predict BRAFV600E Status in Papillary Thyroid Cancer

Background Papillary thyroid carcinoma (PTC) can be predicted from certain suspicious ultrasound (US) features of thyroid nodules. The aim of this study was to examine if these suspicious features can predict the more aggressive PTC associated with B-type Raf kinase (BRAFV600E) mutation. Methods This was a retrospective review of prospectively collected data on patients with PTC and known BRAFV600E status. All patients underwent preoperative US by the same surgeon who performed all the operations. We divided patients into BRAFV600E positive and negative groups. All ultrasonographic data were collected including nodule size, echogenicity, solid or cystic nature, presence of calcifications, irregular margins, and internal vascularity. Results Of 141 patients with PTC, BRAFV600E mutation was detected in 48 (34.0$) patients. There was no significant difference in nodule size (2.06 cm ± 1.37 vs. 2.15 cm ±1.55, p = 0.75) between BRAFV600E positive and negative groups. BRAFV600E positivity was associated with higher rates of -hypoechogenicity (57.5$ vs. 36.6, p = 0.02), calcifications (48.9 vs. 19.4$, p < 0.01), and irregular margins (21.3 vs. 6.5$, p < 0.01). There was no significant difference in the noncystic nature or internal vascularity between BRAFV600E positive and negative groups. The presence of all suspicious US features is associated with a positive predictive value of 100.0$. In the absence of all suspicious features, the negative predictive value was 84.2$. When suspicious lymph nodes (LNs) detected by preoperative US were compared, there was no significant difference between BRAFV600E positive and negative groups (30.6 vs. 21.7$, p = 0.35). Conclusion The presence of multiple suspicious US findings of thyroid nodules can predict the BRAFV600E mutation status of papillary thyroid cancer nodules. The highest accuracy overall (93.2$) was achieved by combining calcification, irregular margins, and hypoechogenicity with extrathyroidal extension and LN metastasis. Future multi-institutional studies are warranted to help surgeons with risk stratification and operative planning for patients with papillary thyroid cancer.
Abstract WP304: Clinician-User Satisfaction With Compass-cp for Stroke

Introduction: COMPASS-CP is a patient-centered electronic application that includes real-time, patient-reported measures of functional and social determinants of health (PROMs). Algorithms assess P...
Squamous Cell Carcinoma

Squamous cell carcinomas are generally localized cutaneous lesions treated with surgical excision. Patients with adenopathy or high-risk lesions may require additional treatment. Cutaneous squamous carcinomas are related to sun exposure, and patients should have lifelong follow-up and skin exams.
One hundred and three new species of Trigonopterus weevils from Sulawesi.

The genus Trigonopterus Fauvel, 1862 is highly diverse in Melanesia, the Moluccas, and the Sunda Islands. Only one species, Trigonopterusfulvicornis (Pascoe, 1885) was so far recorded from Sulawesi. Based on focused field-work the fauna from Sulawesi and nearby islands is here revised. We redescribe T.allotopus Riedel newly recorded for Sulawesi and describe an additional 103 new species: T.abnormissp. n., T.adspersussp. n., T.ambangensissp. n., T.ampanensissp. n., T.analissp. n., T.arachnobassp. n., T.armipessp. n., T.artemissp. n., T.asterixsp. n., T.barbipessp. n., T.bonthainensissp. n., T.carinirostrissp. n., T.castaneipennissp. n., T.celebensissp. n., T.cirripessp. n., T.collarissp. n., T.costatulussp. n., T.curvipessp. n., T.crenulatussp. n., T.crickisp. n., T.darwinisp. n., T.ejaculatoriussp. n., T.fuscipessp. n., T.gracilipessp. n., T.hebertisp. n., T.hirsutussp. n., T.humilissp. n., T.hypocritasp. n., T.idefixsp. n., T.impressicollissp. n., T.incendiumsp. n., T.incognitussp. n., T.indigenussp. n., T.inhonestussp. n., T.invalidussp. n., T.jasminaesp. n., T.klabatensissp. n., T.kolakensissp. n., T.kotamobagensissp. n., T.laevigatussp. n., T.lamprossp. n., T.latipennissp. n., T.lompobattangensissp. n., T.luwukensissp. n., T.mahawuensissp. n., T.manadensissp. n., T.mangkutanensissp. n., T.matalibaruensissp. n., T.mesaisp. n., T.minahassaesp. n., T.moatensissp. n., T.modoindingensissp. n., T.nanussp. n., T.nitidulussp. n., T.obelixsp. n., T.ovalipunctatussp. n., T.ovatulussp. n., T.pagaranganensissp. n., T.palopensissp. n., T.paracollarissp. n., T.paupersp. n., T.pendolensissp. n., T.posoensissp. n., T.prismaesp. n., T.procurtussp. n., T.pseudallotopussp. n., T.pseudanalis, sp. n., T.pseudovatulussp. n., T.pseudovalipunctatussp. n., T.pseudofulvicornissp. n., T.pseudomanadensissp. n., T.pseudosimulanssp. n., T.pumilussp. n., T.rantepaosp. n., T.reticulatussp. n., T.rhombiformissp. n., T.rotundatussp. n., T.rotundulussp. n., T.rudissp. n., T.rufipessp. n., T.sampunensissp. n., T.sampuragensissp. n., T.satyrussp. n., T.scabripessp. n., T.scaphiformissp. n., T.scitulussp. n., T.selayarensissp. n., T.serripessp. n., T.seticnemissp. n., T.silvicolasp. n., T.squalidulussp. n., T.sulawesiensissp. n., T.suturatussp. n., T.tatorensissp. n., T.tenuipessp. n., T.tomohonensissp. n., T.torajasp. n., T.vicinussp. n., T.viduussp. n., T.volcanorumsp. n., T.wangiwangiensissp. n., T.watsonisp. n., and T.yodasp. n. All new species are authored by the taxonomist-in-charge, Alexander Riedel.
Family Separation and the Impact of Digital Technology on the Mental Health of Refugee Families in the United States: Qualitative Study.

Background: Conflicts around the world have resulted in a record high number of refugees. Family separation is a critical factor that impacts refugee mental health. Thus, it is important to explore refugees’ ability to maintain contact with family members across the globe and the ways in which they attempt to do so. It is increasingly common for refugees to use information and communication technologies (ICTs), which include mobile phones, the internet, and social media sites, such as Facebook, WhatsApp, Skype, and Viber, for these purposes. Objective: The aim of this study was to explore refugees’ perceptions of the impact of communication through ICTs on their mental health, the exercise of agency by refugees within the context of ICT use, especially their communication with their families, and logistical issues that affect their access to ICTs in the United States. Methods: We used a constructivist grounded theory approach to analyze in-depth interviews of 290 adult refugee participants from different countries, who were enrolled in a randomized controlled trial of a community-based mental health intervention. Results: Analyses showed that communication through ICTs had differing impacts on the mental health of refugee participants. ICTs, as channels of communication between separated families, were a major source of emotional and mental well-being for a large number of refugee participants. However, for some participants, the communication process with separated family members through digital technology was mentally and emotionally difficult. The participants also discussed ways in which they hide adversities from their families through selective use of different ICTs. Several participants noted logistical and financial barriers to communicating with their families through ICTs. Conclusions: These findings are important in elucidating aspects of refugee agency and environmental constraints that need to be further explicated in theories related to ICT use as well as in providing insight for researchers and practitioners involved in efforts related to migration and mental health.
Enhancing Short Circuit Capability of 1.2-kV Si IGBT Using a Gate-Source Shorted Si Depletion Mode MOSFET in Series With the Emitter

Short-circuit (SC) capability is a critical requirement for power switches in modern power electronics applications. A tradeoff between on-state voltage drop, switching loss, and SC capability of insulated gate bipolar transistors (IGBTs) is performed by manufacturers. In general, IGBTs optimized with low on-state voltage have poor SC capability compared with those with good SC capability. In this report, a novel method is described to improve the SC capability of IGBTs optimized with low on-state voltage drop by using a gate-source-shorted Si depletion-mode (DM) mosfet connected in series with the emitter. A seven-fold increase in the SC capability of commercially available 1.2-kV IGBTs was achieved at high dc bus voltages with minimal impact on on-state and switching loss performance. The proposed method also provides a sensing voltage signal at the drain of the Si DM- mosfet , which can be used to monitor the on-state current magnitude and to detect SC fault conditions.
The Problem of Seduction: Assessing Visual Culture

The thing about popular visual culture is that it is so darned seductive. That's why it engages the interest of children and adults and that's why they return to it over and over again. Why is visual culture so seductive? Not because it is simple. Simplicity is generally not interesting enough to call people back again and again. In fact the best popular visual culture is both complex and highly sophisticated in aesthetic terms. It is seductive in large part because it is highly complex. For example, anyone who has watched the unfolding of the Lord of the Rings films with an analytical eye could talk at length about the layering of images and meaning, the complexity of the stories, the magic of the animation, the sheer power of the aesthetic content, and its connections with fine art. The background material concerning the making of these movies provides fascinating insights into the artistry employed in constructing these pieces of popular visual culture. Surely we have to marvel at the sheer creative ge...
Abstract P4-05-16: Immune landscape of glucocorticoid receptor high breast cancer

BACKGROUND: Glucocorticoid receptor (GR) activation is pro-apoptotic in lymphoid malignancies, whereas in estrogen-receptor negative (ER-) breast cancer, GR activation is anti-apoptotic and associated with relapse through a direct transcriptional role in tumor cells. A meta-analysis of GEO dataset has shown that higher GR expression is associated with an improved relapse free survival (RFS) in ER+ breast cancer but a worse RFS in triple negative breast cancer (TNBC). The relative contributions of GR expression on tumor vs. immune cells which may influence outcomes have not been studied. We hypothesize that there is a difference in the immune landscape between GR-high and GR-low tumors. METHODS: mRNA expression data was accessed from The Cancer Genome Atlas (TCGA) and METABRIC. K-clustering classified GR gene (NR3C1) expression into “high” and “low”. Computer algorithms TIMER, CIBERSORT, Immune pathway gene score, and cytolytic activity score (CYT) were used. Single-cell sequencing data were obtained from GSE75688 and GSE114725 cohorts. RESULTS: 1904 and 1087 pts with stage I-III breast cancer had clinical and genomic data available in METABRIC and TCGA respectively. GR-high tumors had better median overall survival (mOS) [15 vs. 12yrs {HR 0.8(0.71-0.9), p Citation Format: Shipra Gandhi, Ahmed Elkhanany, Mateusz Opyrchal, Elizabeth A Repasky, Kazuaki Takabe. Immune landscape of glucocorticoid receptor high breast cancer [abstract]. In: Proceedings of the 2019 San Antonio Breast Cancer Symposium; 2019 Dec 10-14; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2020;80(4 Suppl):Abstract nr P4-05-16.
LOCAL COMPOSITE QUANTILE REGRESSION SMOOTHING: A FLEXIBLE DATA STRUCTURE AND CROSS-VALIDATION

In this paper, we study the local composite quantile regression estimator for mixed categorical and continuous data. The local composite quantile estimator is an efficient and safe alternative to the local polynomial method and has been well-studied for continuous covariates. Generalization of the local composite quantile regression estimator to a flexible data structure is appealing to practitioners as empirical studies often encounter categorical data. Furthermore, we study the theoretical properties of the cross-validated bandwidth selection for the local composite quantile estimator. Under mild conditions, we derive the rates of convergence of the cross-validated smoothing parameters to their optimal benchmark values for both categorical and continuous covariates. Monte Carlo experiments show that the proposed estimator may have large efficiency gains compared with the local linear estimator. Furthermore, we illustrate the robustness of the local composite quantile estimator using the Boston housing dataset.
Sentiment and Aesthetics in Victorian Photography: The Child Portraits of C. L. Dodgson (Lewis Carroll)

This paper assesses the photography of C. L. Dodgson (Lewis Carroll), particularly his child portraiture, as a portfolio of work, documenting its contents and range, scrutinizing its individual portraits, and assessing its artistic qualities as we see it rather than as mere reflections of the myriad of literary, artistic, sociocultural and psychoanalytic conclusions that have already been drawn about his life and broader works, including his Alice books. Dodgson was in fact a person of education and social position, and enjoyed a social mobility that allowed him to move freely within the artistic, literary, and theatrical circles of his social class, and in particular with the Pre-Raphaelites, and develop his artistic perspectives not to mention ambitions, This paper examines Dodgson’s entire portfolio, close to 2,700 images taken between 1856 and 1882, within the context of Victorian aesthetics that so influenced it.
Self-debriefing in healthcare simulation: An integrative literature review.

Abstract Objectives Debriefing is an essential component of simulation-based education. In-person, facilitator-led debriefing may not always be practical for newer forms of simulation, such as individual virtual simulations. Self-debriefing addresses the issue of practicality, but evidence of implementation and design are unknown. The aims of this review were to explore the use and design of self-debriefing in healthcare simulation and to identify to what extent self-debriefing found in the literature align with the INACSL Standards of Best Practice for debriefing. Design Integrative review. Data sources Peer-reviewed studies indexed within CINAHL, MEDLINE, PsycINFO, ERIC, Education Full Text (H.W. Wilson), Education Source, and Academic Search Premier databases. Review methods A comprehensive database search was conducted using PRISMA guidelines. The INACSL Standard of Best Practice: Simulation Debriefing was used as a framework for analysis. Ten articles were appraised and analyzed for this review. Results Alignment to best practice standards and presence of required criteria varied in self-debriefing designs. Self-debriefs used with graduate-level learners and self-debriefs with higher alignment to standards showed equivalent performance gains when compared to instructor-led debriefs. None of the studies measured reflection capacity despite it being a recommendation. Conclusion Findings indicate that well-designed self-debriefing provides equivalent outcomes to instructor-led debriefing. Best practice recommendations, such as promoting reflection, are underexplored in self-debriefing research.
How relationships bias moral reasoning: Neural and self-report evidence

Abstract Laws govern society, regulating people's behavior to create social harmony. Yet recent research indicates that when laws are broken by people we know and love, we consistently fail to report their crimes. Here we identify an expectancy-based cognitive mechanism that underlies this phenomenon and illustrate how it interacts with people's motivations to predict their intentions to report crimes. Using a combination of self-report and brain (ERP) measures, we demonstrate that although witnessing any crime violates people's expectations, expectancy violations are stronger when close (vs. distant) others commit crimes. We further employ an experimental-causal-chain design to show that people resolve their expectancy violations in diametrically opposed ways depending on their relationship to the transgressor. When close others commit crimes, people focus more on the individual (vs. the crime), which leads them to protect the transgressor. However, the reverse is true for distant others, which leads them to punish the transgressor. These findings highlight the sensitivity of early attentional processes to information about close relationships. They further demonstrate how these processes interact with motivation to shape moral decisions. Together, they help explain why people stubbornly protect close others, even in the face of severe crimes.
Changes in splicing and neuromodulatory gene expression programs in sensory neurons with pheromone signaling and social experience

Social experience and pheromone signaling in ORNs affect pheromone responses and male courtship behaviors in Drosophila, however, the molecular mechanisms underlying this circuit-level neuromodulation remain less clear. Previous studies identified social experience and pheromone signaling-dependent modulation of chromatin around behavioral switch gene fruitless, which encodes a transcription factor necessary and sufficient for male behaviors. To identify the molecular mechanisms driving social experience-dependent neuromodulation, we performed RNA-seq from antennal samples of mutant fruit flies in pheromone receptors and fruitless, as well as grouped or isolated wild-type males. We found that loss of pheromone detection differentially alters the levels of fruitless exons suggesting changes in splicing patterns. In addition, many Fruitless target neuromodulatory genes, such as neurotransmitter receptors, ion channels, and ion transporters, are differentially regulated by social context and pheromone signaling. Our results suggest that modulation of circuit activity and behaviors in response to social experience and pheromone signaling arise due to changes in transcriptional programs for neuromodulators downstream of behavioral switch gene function.
Communicating With Patients and Families During COVID-19

Purpose The COVID-19 pandemic has emphasized the need for clear communication between health care providers and patients and families in many ways. Issues such as mask use and social distancing imp...
Abstract 700: CellSig: A data-driven model of cytokine activity identifies therapeutic targets for severe COVID-19 and cancer immunotherapy-induced colitis

Studies of cytokine activity are foundational to immunology research. However, the complexity and redundancy of cytokine functions have prevented systematic profiling of signaling activities in biological samples. To address these issues, we developed Cell Signaling Analyzer (CellSig, https://cellsig.ccr.cancer.gov), a data-driven infrastructure to model how cytokines cooperate with and antagonize each other in inflammation processes. We manually curated 20,591 transcriptomic profiles related to human cytokine, chemokine, and growth-factor response. CellSig revealed two main cytokine groups typified by NFKB and interferon-associated signals, respectively. The primary pro-inflammatory members of each group induce a distinct set of secondary signals and are repressed by different anti-inflammatory cytokines. CellSig can reliably predict target activities of 43 cytokines using the transcriptomic data from severe COVID-19 cases, cancer immunotherapy-induced colitis, and immune checkpoint blockade response. Among these clinical applications, the differential activities of the NFKB and interferon cytokine groups revealed potential therapeutic targets for alleviating adverse inflammation without compromising viral clearance or cancer treatment. Citation Format: Peng Jiang, Yu Zhang, Beibei Ru, Eytan Ruppin, Kai Wucherpfennig. CellSig: A data-driven model of cytokine activity identifies therapeutic targets for severe COVID-19 and cancer immunotherapy-induced colitis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 700.
Covariance matrix adaptation based tuning of mass spectrometry parameters using experimental probability distributions

The operation of a mass spectrometry instrument, used in analytical chemistry, for custom applications requires the careful tuning of several instrument settings by an expert. In this work, we developed a model that allows the instrument to tune itself. The approach employs a fast, adaptive evolutionary algorithm, the Covariance Matrix Adaptation evolutionary strategy, to tune a mass spectrometry instrument. By developing a scheme for normalizing the values of the outcome variables (resolution, intensity and peak shape of a calibrant peak signal) based on their experimental probability distributions, we combined the outcomes into a single score that was used as the fitness score for the search algorithm. This approach resulted in a more thorough examination of the search space, and in an economical amount of time by being adaptive, resulting in a more stable tuning, no matter the initial state of the settings involved.