cssi/SciSciGPT-SciSciNet huggingface dataset:
Re)Producing American Soldiers in an Age of Empire

While there has been little data gathered as to the presence of migrant workers in service occupations on U.S. military bases in Iraq, the data that do exist along with anecdotal evidence gathered by journalists suggest that the division of reproductive labor on military bases reflects an underexplored axis in the global organization of social reproductive labor. Due in part to the privatization of these services, the vast majority of vital support service labor is outsourced to and performed by men migrating from India, Bangladesh, Sri Lanka, the Philippines, Nepal, and Pakistan. This globalized division of reproductive labor is a site of symbolic politics that reinforces the gendered dimensions of the national identity of the American soldier. This division builds off of a long tradition of gendered dynamics framing military service. The displacement of reproductive labor, which remains coded as effeminate, onto poor migrant men serves to reinforce the aggressive masculine version of American soldiering in a way that smoothes over differences among soldiers along the lines of race, class, rural or urban origin, and even gender. Echoing earlier colonizer–colonized relations, this division of labor in turn supports the increasingly imperial posture that the United States has assumed in the world.
Deletion of the CSB homolog, RAD26, yields Spt(-) strains with proficient transcription-coupled repair.

It has been previously shown that disruption of RAD26 in yeast strain W303-1B results in a strain that is deficient in transcription-coupled repair (TCR), the preferential repair of the transcribed strand of an expressed gene over the non-transcribed strand and the rest of the genome. RAD26 encodes a protein that is homologous to Cockayne syndrome group B protein (CSB) and is a member of the SWI2/SNF2 family of DNA-dependent ATPases involved in chromatin remodeling. Like the rad26 mutant, cells from Cockayne syndrome patients are defective in TCR. We examined the role of Rad26 in TCR by disrupting RAD26 in two repair-proficient laboratory strains and, remarkably, observed no effect upon TCR. Our results indicate that disruption of RAD26 alone is insufficient to impair TCR. Thus, W303-1B must already possess a mutation that, together with disruption of RAD26, causes a deficiency in TCR. We suggest that other genes are mutated in Cockayne syndrome cells that contribute to the deficiency in TCR. Surprisingly, deletion of RAD26 results in expression of genes that are repressed by flanking transposon δ elements, an Spt – phenotype. The δ elements appear to perturb local chromatin structure. Expression of genes flanked by δ elements in rad26∆ mutants is consistent with a role for Rad26 in chromatin remodeling.
Interactive effects of elevated CO2, N deposition and climate change on extracellular enzyme activity and soil density fractionation in a California annual grassland

Elevated CO2, N deposition and climate change can alter ecosystem-level nutrient cycling both directly and indirectly. We explored the interactive effects of these environmental changes on extracellular enzyme activity and organic matter fractionation in soils of a California annual grassland. The activities of hydrolases (polysaccharide-degrading enzymes and phosphatase) increased significantly in response to nitrate addition, which coincided with an increase in soluble C concentrations under ambient CO2. Water addition and elevated CO2 had negative but nonadditive effects on the activities of these enzymes. In contrast, water addition resulted in an increase in the activities of lignin-degrading enzymes (phenol oxidase and peroxidase), and a decrease in the free light fraction (FLF) of soil organic matter. Independent of treatment effects, lignin content in the FLF was negatively correlated with the quantity of FLF across all samples. Lignin concentrations were lower in the aggregate-occluded light fraction (OLF) than the FLF, and there was no correlation between percent lignin and OLF quantity, which was consistent with the protection of soil organic matter in aggregates. Elevated CO2 decreased the quantity of OLF and increased the OLF lignin concentration, however, which is consistent with increased degradation resulting from increased turnover of soil aggregates. Overall, these results suggest that the effects of N addition on hydrolase activity are offset by the interactive effects of water addition and elevated CO2, whereas water and elevated CO2 may cause an increase in the breakdown of soil organic matter as a result of their effects on lignin-degrading enzymes and soil aggregation, respectively.
Guiding Regionalism and Reform from the Court: Judge John Feikens

For decades, federal district court judges have been deeply involved in the reform of state and local government agencies. Some scholars describe such a judicial role in institutional reform as “managerial.” This profile examines the managerial role of Judge John Feikens, who, since 1977, has supervised the Detroit Water and Sewerage Department's attempts to comply with federal laws on wastewater treatment and water quality. Through his sustained, effective oversight, Feikens became an influential mediator of metropolitan cooperation. His persistence in resolving metropolitan conflict may be viewed with concern by those who worry about lengthy court involvement in public administration. However, this insightful profile underscores poignant contemporary lessons, even from judicial actions, for enhancing metropolitan problem solving.
The Effects of Self-Esteem, Success-Failure, and Self-Consciousness on Task Performance

Previous research has demonstrated that the task performance of low selfesteem individuals (low SEs) suffers in the presence of self-focusing stimuli (e.g., a mirror). The present study was designed to determine if such stimuli must inevitably have adverse effects on low SEs. It was reasoned that if low SEs were provided with success feedback from a previous task, then the nature of their self-consciousness would be altered on a subsequent task. Specifically, low SEs should attend more to positive and less anxiety-provoking aspects of themselves than would low SEs who received failure feedback from the previous task. Under the former condition, the low SEs' subsequent task performance was expected to improve. For high self-esteem individuals (high SEs), who typically perform well, previous success-failure feedback was expected to have little effect on subsequent performance. In a three-factor design, subjects high and low in chronic self-esteem received false success or failure feedback from a previous task and completed a concept formation task in either the presence or the absence of a mirror. Whereas high SEs performed equally well following success or failure, low SEs in the success condition performed significantly better than low SEs in the failure condition (and just as well as high self-esteem-success participants). This Self-Esteem X Prior Feedback interaction was significant in the presence of the mirror, but not in its absence. In the absence of the mirror, however, this interaction was observed for subjects who were high in dispositional self-consciousness, but not for those who were low. Practical and theoretical implications of these findings are discussed.
Grub Street Commerce: Advertisements and Politics in the Early Modern British Press

In mid‐May 1689 James Welwood, Scottish‐born physician and polemicist for the dual monarchs William III and Mary II, inaugurated a popular journal of opinion, Mercurius Reformatus or the New Observ...
Consumption and Investment Motives and the Portfolio Choices of Homeowners

This article investigates the portfolio choices of homeowners, taking into account the investment constraint introduced by Henderson and Ioannides (1983). This constraint requires housing investment by homeowners to be at least as large as housing consumption. It is shown that when the constraint is binding, the homeowner's optimal portfolio is ineffcient in a mean-variance sense. Thus, portfolio inefficiency is not an indication that consumers are irrational or careless in their financial decisions. Instead, inefficiency can be seen as the result of a rational balancing of the consumption benefits and portfolio distortion associated with housing investment.
“Buy Me a Bride”: Death and Exchange in Northern Japanese Bride‐Doll Marriage

In the northern Japanese memorial practice of “bride-doll marriage/” which emerged during World War II, the soul of a dead child is married to a spirit spouse embodied in a consecrated figurine. These marriages stimulate limited exchange relationships between the living and dead by building on old and new modes of gifting and circulation, including the prestation of Bodhisattva statues, affinity, transmigration, and the abstraction of social relations made possible by modern commodity forms. Motivated by a strong sense of unfulfilled obligation toward the deceased, these restricted acts of exchange culminate in the cessation of exchange transactions between the living and specific dead persons. In this respect, spirit marriage is profoundly unlike conventional marriage among the living, which leads to ramifying exchange relations between a growing number of persons over time. [Japan, memorialization, mortuary ritual, commodities, Buddhism]
Possible role for dietary lutein and zeaxanthin in visual development

The possibility that the macular carotenoids, lutein (L), and zeaxanthin (Z), could retard age-related changes in the eye and prevent the eye diseases that result from such changes (namely, cataract and macular degeneration) has been carefully studied. A role for the carotenoids very early in life, however, has received far less attention. Nevertheless, an influence on visual development is likely. Retinal L and Z, for instance, would influence the development of the visual system if they 1) altered input during a critical/sensitive period of visual development and/or 2) influenced maturation and/or 3) protected the retina during a period when it was particularly vulnerable. The available evidence indicates that the pigments may play a role in all three of these areas.
Type A aortic dissection in Marfan syndrome: a case for more aggressive and extensive surgery at the time of the initial surgical operation.

In the article by Rylski et al1 in this issue of Circulation , the authors investigate the long-term outcomes of repair for type A aortic dissection in patients with Marfan syndrome. Article see p 1381 Marfan syndrome is one of the genetic syndromes associated with thoracic aortic aneurysms and aortic dissection. The syndrome is the result of fibrillin-1 gene mutation ( FBN-1 ), which is an autosomal-dominant mutation with variable expression. Fibrillin-1 is a large glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils are present in elastic connective tissue such as the medial layer of the ascending aorta and in nonelastic connective tissue throughout the entire body. The criteria for Marfan syndrome include the presence of clinical findings in the cardiovascular, ocular, and skeletal systems and a positive family history, even though ≈25% of patients have a negative family history and FBN-1 mutations= status.2 Patients with Marfan syndrome are predisposed to have thoracic aortic aneurysms involving the aortic root, ascending aorta, arch, and descending thoracic aorta. The majority of the patients with Marfan syndrome will present with dilation of the aortic root and ascending aorta, and the degree of severity of the disease increases with the extension of the dilation beyond the ascending aorta. Current guidelines3 recommend surgical repair for an external diameter of 5.0 cm, unless rapid growth, defined as >0.5 cm/y has occurred or in the presence of significant aortic regurgitation …
PERFECT MATCHINGS IN PLANAR CUBIC GRAPHS

A well-known conjecture of Lovasz and Plummer from the mid-1970’s, still open, asserts that for every cubic graph G with no cutedge, the number of perfect matchings in G is exponential in |V (G)|. In this paper we prove the conjecture for planar graphs; we prove that if G is a planar cubic graph with no cutedge, then G has at least $$2^{{{\left| {V(G)} \right|} \mathord{\left/ {\vphantom {{\left| {V(G)} \right|} {655978752}}} \right. \kern-\nulldelimiterspace} {655978752}}}$$ perfect matchings.
Four plasmepsins are active in the Plasmodium falciparum food vacuole, including a protease with an active-site histidine

Hemoglobin degradation is a metabolic process that is central to the growth and maturation of the malaria parasite Plasmodium falciparum. Two aspartic proteases that initiate degradation, plasmepsins (PMs) I and II, have been identified and extensively characterized. Eight additional PM genes are present in the P. falciparum genome. To better understand the enzymology of hemoglobin degradation, it is necessary to determine which of these genes are expressed when hemoglobin degradation is occurring, which encode active enzymes, and which gene products are found in the food vacuole where catabolism takes place. Our genome-wide analysis reveals that PM I, II, and IV and histo-aspartic protease encode hemoglobin-degrading food vacuole proteases. Despite having a histidine in place of one of the catalytic aspartic acids conserved in other aspartic proteases, histo-aspartic protease is an active hydrolase.
Flash-based logging for database updates

Flash Memories (FM) are gaining popularity because they are purely digital storage device, they do not have any mechanical latency, they are highly portable, and they are easy to use for accessing data especially for mobile units such as laptops, PDA, etc. For these reasons they have a much diversified application domain. Many vendors are replacing conventional Disk-Based memory with FM. With recent advancements in FM technology, they may soon be able to replace conventional disk drive for mobile database processing, at least for lightweight tasks. Although FMs are faster than conventional magnetic discs, there are still many issues to solve to improve their performance specifically the writing speed. In this paper we present a software solution to improve its performance for database activities. We refer to our scheme as “Flash-Based Logging for Database Updates.” The scheme optimizes the use of costly writing/erasing operations of FMs using log based delayed update techniques. We show that our scheme reduces the randomness of read/write queries by grouping techniques. We argue that our scheme has a potential of achieving significant performance gain in mobile database processing.
Evolution of an introductory computer science course: the long haul

University requirements for the material covered in introductory computer science courses have evolved over the years, and those courses must therefore evolve as well. In this paper, we discuss the 7-year evolution of such a course at the U.S. Air Force Academy. In 1995, the main thrust of the course was to develop students' programming skills to support later programming activities, even for those students not majoring in computer science. Although some general survey topics were covered, programming skill development was the main goal of the course. Since that time, the course has evolved significantly into a course that covers general computer science and Information Technology (IT) topics in greater depth and breadth, with a continuing but greatly reduced programming component. During that 7-year period, we changed programming languages for the course, significantly changed the way in which we evaluated programming ability, incorporated graphics into the course, conducted an extensive rework of the course content, and made numerous smaller changes as well. In this paper, we discuss the technical and political issues associated with the evolution of the course. Although this work is presented in the context of our course, such evolution is clearly applicable to other introductory courses as well.
Building scenarios for ecosystem services tools: Developing a methodology for efficient engagement with expert stakeholders

Abstract The ecosystem services framework provides a holistic perspective for planning on local, national, and global scales. Often, scenarios are utilized to quantify and contrast the potential impacts of anthropocentric or climatic drivers of change on ecosystem services. One freely available modeling suite, Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST), from the Natural Capital Project, aims to aid in decision making and planning processes by quantifying ecosystem services in spatially explicit context. Several of their modeling tools require land cover data layers, and the user can generate future land cover data layers through the scenario generator tool, released in 2014. The tool’s associated literature emphasizes the integration of stakeholders into the scenario generating process to help create plausible and relevant scenarios, often through workshops. Our study reviews the tool and presents an alternative methodology for engaging expert stakeholders in the scenario generation process through a less time intensive format than the recommended workshops—a detailed questionnaire. We find that there is a need for systematic decision making analysis of stakeholder input before scenarios can be created, and we used cumulative percent frequency analysis of questionnaire responses to dictate scenario generation transition tables, when appropriate. We conclude that using a questionnaire to elicit input from expert stakeholders to develop land cover scenarios may be a time and cost effective alternative that still provides realistic and usable inputs when compared to workshops.
Growth Inhibition of Dalmatian Toadflax, Linaria dalmatica (L.) Miller, in Response to Herbivory by the Biological Control Agent Mecinus janthinus Germar

Our study reports the results of field and garden experiments designed to quantitatively evaluate the impact of herbivory by a weed biological control agent, the stem-mining weevil Mecinus janthinus Germar, on the growth of its exotic host Dalmatian toadflax, Linaria dalmatica (L.) Miller. Herbivory by M. janthinus under both natural and manipulated environmental conditions inhibited L. dalmatica growth. Reductions in stem length, biomass, and growth were more pronounced for plants subjected to both exophagous (adult) and endophagous (larval) feeding injury than for plants exposed only to adult folivory. Decreases we observed in root biomass could additionally inhibit shoot production from lateral roots. This provides a plausible mechanism explaining anecdotal reports correlating the reduced spread of L. dalmatica with attack by M. janthinus. Our results indicate that L. dalmatica growth is compromised once a threshold density equivalent to 5 M. janthinus larvae per stem is exceeded. The consistency of gr...
The Hyperpolarization-Activated Cation Current Ih: The Missing Link Connecting Cannabinoids to Cognition

In this issue of Neuron, Maroso et al. (2016) describe a novel link between cannabinoids and cognition. They show that CB1Rs bidirectionally modulate HCN-mediated Ih in a subset of CA1 pyramidal neurons to influence both short- and long-term circuit dynamics and alter spatial working memory in behaving mice.
Mesh colors

The coloring of 3D models using 2D or 3D texture mapping has well-known intrinsic problems, such as mapping discontinuities and limitations to model editing after coloring. Workarounds for these problems often require adopting very complex approaches. Here we propose a new technique, called mesh colors, for associating color data directly with a polygonal mesh. The approach eliminates problems deriving from using a map from texture space to model space. Mesh colors is an extension of vertex colors where, in addition to keeping color values on each vertex, they are also kept on edges and faces. Like texture mapping, the approach allows higher texture resolution than model resolution, but at the same time it guarantees one-to-one correspondence between the model surface and the color data, and eliminates discontinuities. We show that mesh colors integrate well with the current graphics pipeline and can be used to generate very high-quality textures.
Vesical Endometriosis: A Review and 2 Case Reports

AbstractVesical endometriosis is uncommon and can result in months or years of morbidity if undetected. We report 2 cases that demonstrate that increased awareness of this entity and expeditious use of appropriate diagnostic techniques can lead to earlier diagnosis and definitive treatment.
Motivation and Engagement in Authorship Learning

ABSTRACTConstructionist principles provide fertile ground for developing innovative approaches to learning. Using a grounded theory qualitative research design, we analyzed participant reports of their experience in an online course in which they collaboratively authored a book. Our qualitative analysis suggested that participants experienced extraordinary engagement and motivation, which they interpreted as being related to the collaborative process, their own agency in the project, and the externalized value of creating an artifact intended for a public audience. A new metaphor for learning emerged from the study based on the concept of authorship. Our authorship learning construct sees learning as a process of authoring understanding and skills while simultaneously authoring at multiple levels of agency, including authorship of processes, roles, goals, artifacts, meaning, self, group identity, and society.
Do perceptions of family-centered care differ in older and younger family/caregivers of U.S. veterans?

INTRODUCTION Family-centered care (FCC) involves partnering with patients and family/caregivers ("caregivers"), engaging them in decisions, and providing support. FCC may be measured across 3 dimensions: respect, collaboration, and support and needs likely vary by caregiver age. The objective was to examine and compare caregiver perceptions of FCC by age. METHOD We mailed surveys to family/caregivers of Veterans. We collected demographics and measured respect, collaboration, and support using the Family-Centered Care Survey (FCCS). We calculated mean values and conducted bivariate comparisons, dichotomized by caregiver age (≥60 vs. <60), of demographics and FCC constructs. We completed thematic analysis on open-ended text. RESULTS Caregivers (n = 2,111) aged ≥60 versus <60 were more likely to be spouses (81% vs. 62%, p < .0001) and White (74% vs. 50%, p < .0001). Overall FCC subscales values were high: respect (3.30), collaboration (3.07), and support (2.99). Older caregivers reported higher respect (3.36 vs. 3.22, p < .001), collaboration (3.12 vs. 2.98, p < .0001), and support (3.06 vs. 2.88, p < .0001). Qualitative analysis revealed collaboration, communication, hospital climate, and physical environment as important to FCC and supplemented quantitative findings on age. Examples highlighted both positive perceptions of FCC and areas of concern, such as feeling "unheard" and "like I am bothering providers," and needing "more comfortable seating" and "better parking." DISCUSSION Caregivers perceived high FCC levels at VA facilities, reporting highest on respect and lowest on support. Older caregivers perceived better FCC compared with younger caregivers. Several concerns identified can be used to target improvements to FCC including: improved support, collaboration between patient/family/provider, and climate/environmental enhancements. (PsycINFO Database Record
Abstract 3027: A novel function of EGFR in epigenetic modulation via hMOF in breast cancer .

Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC The epidermal growth factor receptor (EGFR) is aberrantly active in breast cancer, initiates and drives tumorigenic pathways, and has been implicated in multiple tumorigenic processes including hyperplasia, chemo-resistance and metastasis. Histone lysine modifications directly influence activation and repression of transcription. MYST family acetyltransferase, human males absent on the first (hMOF), plays an important role in transcription activity through histone H4K16 acetylation. Loss of hMOF and subsequently the absence of H4K16 acetylation have been shown to be a common feature in human cancer including breast cancer. However, the regulation of hMOF remains largely unknown. Recently, we have discovered the acetylation of EGFR in human breast cancer cells. Thus, we screened a set of EGFR-interacting acetyltransferases using co-immunoprecipitation analysis and ingenuity pathway analysis (IPA). Here, we found that EGFR directly interacts with and phosphorylates hMOF. EGFR-induced phosphorylation hMOF was significantly reduced in the hMOF YF mutant. Indeed, hMOF YF mutant showed a higher histone acetyltransferase (HAT) activity compare to wild type hMOF. In addition, tyrosine kinase inhibitor (TKI) also enhanced the HAT activity of wild type hMOF. Furthermore, we found that EGFR modulates acetylation status of histone H4K16 via phosphorylating hMOF. We anticipate our study of EGFR and hMOF to be of therapeutic relevance, possibly leading to novel discovery in drug development targeting the receptor tyrosine kinase and the acetylation process. Citation Format: Seung-Oe Lim, Chia-Wei Li, Shih-Shin Chang, Jia Shen, Mien-Chie Hung. A novel function of EGFR in epigenetic modulation via hMOF in breast cancer . [abstract]. In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 3027. doi:10.1158/1538-7445.AM2013-3027
Detection of ribonucleic acid with pyronin.

Pyronin, when used in the methyl green-pyronin stain, is useful in localizing ribonucleic acid (RNA). That it has rarely been used alone is perhaps a result of the observation (Kurnick 1955) that pyronin stains deoxyrobonucleic acid (DNA) of animal tissue when not competitively inhibited by methyl green. The tests described in this note indicate that pyronin alone can be used to demonstrate RNA in fixed plant tissues.
Endoscopic therapy for bleeding from the upper gastrointestinal tract.

PreviewThe evolution of endoscopy from a purely diagnostic tool to a therapeutic weapon has dramatically altered the approach to several serious gastrointestinal problems. Careful scrutiny of outcomes, complications, and costs may be forgotten in the rush to apply this weapon, and largely unproven procedures may become standards of care. Case series, rather than controlled trials, become the basis for decision making. Dr Lieberman reviews advances in endoscopic management of acute upper gastrointestinal bleeding and highlights some areas of controversy.
Electromagnetically Induced Transparency in Rubidium Atoms: Enhancement of Four-Wave Mixing

CW-electromagnetically induced transparency (EIT) has been observed both in a lambda-type1 and a ladder-type2 three-level system of rubidium atoms. In particular, quantum interference of life-time broadened dressed states has been observed directly and dispersion properties of EIT were measured.1,2 In this paper, we report an experiment on enhancement of non-degenerate four-wave mixing (NDFWM) using EIT in a lambda-type three-level system of rubidium atoms.
Loss Functions and Stochastic Approximation

Gradient descent as a technique for finding the minimum of a loss function J(v) was introduced in Section 2.10. Recall that the technique consists of finding the gradient ∇ J(v) and then adjusting the parameter vector v so that the change in v is in the direction of the negative of the gradient.
Summing UP II

The wealth of ideas discussed at this symposium makes the task of summing up unusually difficult. I am, therefore, delighted that Marcel Bessis noted that I am to give my views and impressions, not a complete and evenhanded summary.
Enhancing Relational Database Security by Metadata Segregation

Abstract Although many prominent Relational Database Management Systems provides inbuilt security controls and mechanisms, the information resided in the data-store are at great risk. This research aims to reduce the risk of unauthorized data access by providing an extra layer of security. This research proposes a novel method for incorporating information security while designing the relational database by segregating the information on the basis of its sensitivity level and creating referential integrity constraints dynamically at run time. Different techniques to identify and quantify sensitive attributes and restructuring database architecture have been discussed for the proposed approach. The primary keys of the restructured tables and most critical information attributes were secured using Transparent Data Encryption utility provided by Oracle 11 g to prohibit illegitimate use of information. The performance of the proposed architecture was evaluated with 1,000,000 records which shows that by increasing the number of records, the response time of Select statement increased dramatically whereas it increased gradually for Insert, Update and Delete operations.
C(sp3)−H Oxidative Addition and Transfer Hydrogenation Chemistry of a Titanium(II) Synthon: Mimicry of Late‐Metal Type Reactivity

Two-electron reduction of the TiIV compound (ketguan)(ImDippN)Ti(OTf)2 (3) gives the arene-masked complex (ketguan)(η6-ImDippN)Ti (1) in excellent yield. Upon standing in solution, 1 converts to a TiIV metallacycle (4) through dehydrogenation of a pendant isopropyl group. Spectroscopic evidence shows this transformation initially proceeds via the oxidative addition of a C(sp3)−H bond and can be reversed upon exposure of 4 to H2. Interestingly, treatment of 1 with cyclohexene gives cyclohexane and 4 via a titanium-mediated transfer hydrogenation reaction, a process that can be extended to catalytically hydrogenate other unsaturated hydrocarbons under mild conditions. These results, rare for the early-metals, suggest 1 possesses chemical characteristics reminiscent of noble, late-metals.
Design Study of a 900 MHz/1.8 GHz CMOS Transceiver for Dual-Band Applications

This chapter describes the design of a CMOS transceiver targeting dual-band applications in the 900 MHz and 1.8 GHz bands. The receiver is based on a modified Weaver architecture, and the transmitter incorporates new methods of quadrature up-conversion. The receiver and the transmitter have been fabricated in a 0.6μm CMOS technology.
Technetium pyrophosphate uptake in transthyretin cardiac amyloidosis: Associations with echocardiographic disease severity and outcomes

Background Quantitative uptake of Technetium 99 m-pyrophosphate (TcPYP) is sensitive and specific for diagnosing transthyretin cardiac amyloidosis (ATTR). We sought to examine the association between TcPYP uptake intensity and echocardiographic measures of disease severity and clinical outcomes.
Control of Selectivity through Synergy between Catalysts, Silanes, and Reaction Conditions in Cobalt-Catalyzed Hydrosilylation of Dienes and Terminal Alkenes

Readily accessible (i-PrPDI)CoCl2 [i-PrPDI = 2,6-bis(2,6-diisopropylphenyliminoethyl)pyridine] reacts with 2 equiv of NaEt3BH at −78 °C in toluene to generate a catalyst that effects highly selective anti-Markovnikov hydrosilylation of the terminal double bond in 1,3- and 1,4-dienes. Primary and secondary silanes such as PhSiH3, Ph2SiH2, and PhSi(Me)H2 react with a broad spectrum of terminal dienes without affecting the configuration of the other double bond. When dienes conjugated to an aromatic ring are involved, both Markovnikov and anti-Markovnikov products are formed. The reaction is tolerant of various functional groups such as an aryl bromide, aryl iodide, protected alcohol, and even a silyl enol ether. Reactions of 1-alkene under similar conditions cleanly lead to a mixture of Markovnikov and anti-Markovnikov hydrosilylation products, where the ratio of the products increasingly favors the latter, as the size of the 2,6-substituents in the iminoylaryl group becomes larger. The complex (i-PrPDI)CoC...
One Point of View: Industrial Expectations and the Research Universities

(1994). One Point of View: Industrial Expectations and the Research Universities. Research-Technology Management: Vol. 37, No. 6, pp. 9-10.
Application of text information extraction system for real-time cancer case identification in an integrated healthcare organization

Background: Surgical pathology reports (SPR) contain rich clinical diagnosis information. The text information extraction system (TIES) is an end-to-end application leveraging natural language processing technologies and focused on the processing of pathology and/or radiology reports. Methods: We deployed the TIES system and integrated SPRs into the TIES system on a daily basis at Kaiser Permanente Southern California. The breast cancer cases diagnosed in December 2013 from the Cancer Registry (CANREG) were used to validate the performance of the TIES system. The National Cancer Institute Metathesaurus (NCIM) concept terms and codes to describe breast cancer were identified through the Unified Medical Language System Terminology Service (UTS) application. The identified NCIM codes were used to search for the coded SPRs in the back-end datastore directly. The identified cases were then compared with the breast cancer patients pulled from CANREG. Results: A total of 437 breast cancer concept terms and 14 combinations of “breast” and “cancer” terms were identified from the UTS application. A total of 249 breast cancer cases diagnosed in December 2013 was pulled from CANREG. Out of these 249 cases, 241 were successfully identified by the TIES system from a total of 457 reports. The TIES system also identified an additional 277 cases that were not part of the validation sample. Out of the 277 cases, 11% were determined as highly likely to be cases after manual examinations, and 86% were in CANREG but were diagnosed in months other than December of 2013. Conclusions: The study demonstrated that the TIES system can effectively identify potential breast cancer cases in our care setting. Identified potential cases can be easily confirmed by reviewing the corresponding annotated reports through the front-end visualization interface. The TIES system is a great tool for identifying potential various cancer cases in a timely manner and on a regular basis in support of clinical research studies.
Higher education culture and the diffusion of technology in classroom instruction

INTRODUCTION The diffusion of an innovation takes, on an average, 25 years in an educational setting. Many factors contribute to this slow acceptance rate. Rogers’ (1995) theory on the diffusion of innovation and the influence of culture on such diffusion is used to shed light on the causes for this slow diffusion. While not a full explanation of this slow rate of change, this case study shows that the academic culture, within which faculty function, has a strong influence on the diffusion of the use of technology in classroom instruction. This case study provides a point of reference for further study of diffusion of technology in classroom instruction. This case focuses on a Research I institution in the Midwest that has made a number of commitments to the integration of technology into the curriculum and has channeled many resources into this campaign. While the institution has invested large sums of money in the development of the infrastructure, the rate at which faculty have adopted the use of technology in their teaching has remained low. In order to determine the perceptions of faculty and develop some framework for understanding why the infusion of technology into classroom instruction was so low, faculty members on the campus were interviewed, focus groups were conducted, and meetings between faculty and administrators concerning technology issues were observed. Because additional issues exist with distance education, the scope of this case study research was limited to on-campus classroom instruction and support.
COURT-ANNEXED ARBITRATION

Publisher Summary This chapter describes the court-annexed arbitration. Court-annexed arbitration programs can be established by statute or court rule. Established, all programs authorize trial courts to require arbitration of civil suits that fall within a specified jurisdiction as a precondition for placing those suits on the trial calendar. Arbitration generally results in an award that has the force of a court judgment, if the award is accepted by the parties. If any party is dissatisfied with the award, he or she may reject it and request that the case be calendared for a trial de novo . In many programs, appellants who request de novo trials are required to reimburse the court for the arbitrator's fees and in some programs, court costs and attorney fees may also be levied on unsuccessful appellants. Such fees are intended to discourage frivolous appeals. In all court-annexed arbitration programs, cases assigned to arbitration are heard by one or more private attorneys or retired judges who agree to serve as arbitrator.
Control of Synthesis and Release of Anterior Pituitary Hormones in vitro

Summary Control of anterior-pituitary function by the brain, particularly its hypothalamic region, appears to be well established. In recent years, it has been demonstrated that separate hypothalamic neurohormones regulate the synthesis and release of each of the six anterior-pituitary hormones. The first of these to be reported was the corticotropin-releasing factor (CRF) by Saffran and Serially (1955), who observed that hypothalamic extracts induced release of ACTH from the incubated pituitary. Hypothalamic release of the other five factors regulating anterior-pituitary hormones have been reported by us and others since 1960. We have developed in vitro assays for the following five hypothalamic factors: prolactin inhibiting factor (PIF), growth-hormone-releasing factor (GH-RF), follicle-stimulating hormone-releasing factor (FSH-RF), luteinizing-hormone-releasing factor (LRF) and thyrotropichormone-releasing factor (TRF). Rat anterior pituitary is incubated together with hypothalamic extract in a physiological medium at body temperature for one to six hours, at the end of which time the medium is removed and assayed for the particular hormone under study by a standard bio-assay procedure. These in vitro methods have several advantages: (1) they permit us to study the direct effects of a hypothalamic extract on the anterior pituitary, without interference by other body influences, (2) the concentrations of hypothalamic extract added to the incubation medium exhibits a log-dose relationship in respect to the amount of hormone released by the pituitary tissue. This indicates we are dealing with specific neurohormones in the hypothalamus, since nonspecific substances do not elicit such responses by the pituitary, (3) we can assay quantitatively each of these releasing factors in the hypothalamus, (4) by culturing the pituitary for several days, we can demonstrate that hypothalamic extracts induce synthesis as well as release of anterior-pituitary hormones. PIF inhibits synthesis and release of prolactin by the pituitary. During the past several years, we have studied the action of exteroceptive and enteroceptive stimuli on the hypothalamic content of releasing or inhibiting factors, and have attempted to corelate this with pituitary-hormone concentration and effects on target organ. Some of these studies are described.
Sex-based differences in outcomes, 30-day readmissions, and costs following catheter ablation of atrial fibrillation: the United States Nationwide Readmissions Database 2010–14

AIMS Although catheter ablation has emerged as an important therapy for patients with symptomatic atrial fibrillation (AF), there are limited data on sex-based differences in outcomes. We sought to compare in-hospital outcomes and 30-day readmissions of women and men undergoing AF ablation. METHODS AND RESULTS Using the United States Nationwide Readmissions Database, we analysed patients undergoing AF ablation between 2010 and 2014. Based on ICD-9-CM codes, we identified co-morbidities and outcomes. Multivariable logistic regression and inverse probability-weighting analysis were performed to assess female sex as a predictor of endpoints. Of 54 597 study patients, 20 623 (37.7%) were female. After adjustment for age, co-morbidities, and hospital factors, women had higher rates of any complication [adjusted odds ratio (aOR) 1.39; P < 0.0001], cardiac perforation (aOR 1.39; P = 0.006), and bleeding/vascular complications (aOR 1.49; P < 0.0001). Thirty-day all-cause readmission rates were higher for women compared to men (13.4% vs. 9.4%; P < 0.0001). Female sex was independently associated with readmission for AF/atrial tachycardia (aOR 1.48; P < 0.0001), cardiac causes (aOR 1.40; P < 0.0001), and all causes (aOR 1.25; P < 0.0001). Similar findings were confirmed with inverse probability-weighting analysis. Despite increased complications and readmissions, total costs for AF ablation were lower for women than men due to decreased resource utilization. CONCLUSIONS Independent of age, co-morbidities, and hospital factors, women have higher rates of complications and readmissions following AF ablation. Sex-based differences and disparities in the management of AF need to be explored to address these gaps in outcomes.
Good-natured comedy to enrich climate communication

AbstractThis report explores the use of good-natured comedy to diversify the modes of comedy that can be used in climate communication beyond satire to others modes that are possibly more supportiv...
The productive uncertainty of indigenous and decolonizing methodologies in the preparation of interdisciplinary STEM researchers

This study, undertaken in the Northwest USA, explores how graduate students in an interdisciplinary social–ecological systems research course engaged with concepts of epistemic difference and Indigenous knowledge as part of a required module titled “Ways of Knowing” to engage social and ecological change in climate science. We describe how graduate students engaged with Indigenous ways of knowing and discussion of interdisciplinary equity across knowledge systems and methodologies. Analysis of student perspectives drawn from fieldnotes, student course work, and post-course interviews illuminates tensions in preparing interdisciplinary science researchers to navigate epistemic difference. Students embraced Indigenous ways of knowing as useful for conceptualizing complex tensions in social–ecological systems research, while simultaneously sidestepping deeply rooted issues of power and coloniality in research. We trace two primary ways Indigenous ways of knowing informed interdisciplinary processes in students’ conceptualizations of social–ecological challenges: Science as more expansive: Reflexivity and interpersonal dilemmas; and Grappling with power and settler colonial discomfort. We argue that continued engagement in epistemic difference, particularly Indigenous knowledges, is necessary for cultivating scientific engagement in complex notions of knowledge equity in climate sciences involving Indigenous peoples/lands. Finding underscore how changes in graduate research training can expand research imaginaries, however, such expansions need to be systematic and multi-stranded to interrupt the deep-rooted marginalization of non-Western knowledges in scientific research.
Postoperative radiation therapy vs observation for pN1 oral cavity squamous cell carcinoma.

BACKGROUND American Society of Clinical Oncology guidelines recommend that the decision to give postoperative radiotherapy (PORT) for pN1 oral cavity squamous cell carcinoma (OCSCC) without other adverse features be based on the adequacy of the neck dissection ( 10 mm LN metastasis derived greater benefit compared with patients with smaller metastases. CONCLUSIONS In pN1 OCSCC without other adverse features, the size of the LN metastases may predict benefit from PORT, whereas the adequacy of the neck dissection may not.
Foundations of information ethics: edited by John T. F. Burgess and Emily J. M. Knox, Chicago, IL, American Library Association, 2019, 168 pp., $54.99, ISBN: 978-0-8389-1722-0

Given the recent surge in news headlines regarding intellectual property, international privacy laws, and cybersecurity concerns, editors John T. Burgess and Emily J. M. Knox have assembled a timel...
Broadway to Main Street: How Show Tunes Enchanted America: by Laurence Maslon, New York, NY, Oxford University Press, 2018, 252 pp., $34.95 (paper), ISBN: 978-0-19-983243-8

How did Broadway get to be so popular in American music? Broadway to Main Street: How Show Tunes Enchanted America by Laurence Maslon provides an overview of the impact of Broadway showtunes on Ame...
Failure of passive transfer in foals

Foals are born with a naive immune system, and rely upon the ingestion and absorption of immunoglobulins from the dam's colostrum to obtain passive immunity. Failure of passive transfer (FPT) is th...
Maternal stress and the ZIKV epidemic in Puerto Rico

In the summer of 2016, we examined the impact of the ZIKV crisis on women’s experiences of perinatal stress in Puerto Rico. Twenty-two pregnant or recently postpartum women engaged in qualitative i...
Multi-Perspective Semantic Information Retrieval

Information Retrieval (IR) is the task of obtaining pieces of data (such as documents or snippets of text) that are relevant to a particular query or need from a large repository of information. While a combination of traditional keyword- and modern BERT-based approaches have been shown to be effective in recent work, there are often nuances in identifying what information is "relevant" to a particular query, which can be difficult to properly capture using these systems. This work introduces the concept of a Multi-Perspective IR system, a novel methodology that combines multiple deep learning and traditional IR models to better predict the relevance of a query-sentence pair, along with a standardized framework for tuning this system. This work is evaluated on the BioASQ Biomedical IR + QA challenges.
Running on Empty: Warning Signs of Compassion Fatigue and Burnout

This chapter will examine how the toxin handling role can result in compassion fatigue and burnout. It will also explore ways to identify these issues and how to avoid and/or deal with them. Takeaways for Practitioners An understanding of the similarities and differences between toxin handling, compassion fatigue, and burnout Strategies to avoid and/or deal with these issues if they are impacted by them
Introductory guide to the application of XPS to epitaxial films and heterostructures

XPS is an important characterization method for epitaxial films and heterostructures. Although standard approaches for XPS data collection and analysis provide useful information such as average composition and the presence of contaminants, more in-depth analyses provide information about the film structure, surface termination, built-in electric potentials, and band offsets. The high degree of structural order in these materials enables such information to be extracted from spectral data but also adds complications to the analysis. This guide highlights three topics of importance in this field: (i) the impacts of crystallinity on XPS signals and quantification, (ii) the unexpected spectral line shapes that can occur in unusual or novel materials, and (iii) the ability of XPS to yield information about built-in potentials and band offsets. Concepts are demonstrated using complex oxide heterostructures. Although these topics are highly relevant to epitaxial films and heterostructures, they also apply to single crystals of complex materials.