cssi/SciSciGPT-SciSciNet huggingface dataset:
Stylizing Genderlect Online for Social Action: A Corpus Analysis of ‘BIC Cristal for Her’ Reviews

This article introduces the concept of stylization and illustrates its usefulness for studying online discourse by examining how writers have employed it in order to parody sexist products such as BIC Cristal for Her, using genderlect in order to introduce dissonance into and reframe patriarchal discourse. A corpus analysis of 671 reviews, written from August through October 2012, confirmed a dramatically higher presence of lexical items and adjectives often stereotyped as feminine, compared to a reference corpus of other parody reviews, as well as the GloWbe corpus housed at Brigham Young University. A qualitative analysis shows the stylized use of these features, and how they contribute to the construction of personas that are intended to mock the sexism inherent in BIC’s advertising. This analysis hopes to encourage more attention to how stylization functions in emerging online genres.
Conformation and Soundness

Conformational problems tend to be common in llamas and alpacas. Without setting a standard, basic conformation can still be evaluated by comparing with equine conformation, especially in terms of straightness of limbs. Good conformation should evoke a sense of balance in the observer. Conformation faults predispose to unsoundness.
Integrated Care and Specialty Behavioral Health Care in the Patient-Centered Medical Home

Integrated health care represents the contemporary recognition that holistic, whole-person, and patient-centered medical home (PCMH) services are effective in terms of improved treatment outcomes for mental health (MH), substance abuse, and physical illness, as well as more cost-effective for both patients and health-care systems. These benefits are obtained, for instance, through a reduction in expensive emergency department visits and overutilization of health-care services in service delivery settings with integrated physical health primary care (PC) and behavioral health services. In fact, evidence suggests that the myriad benefits of integrated care (IC) models, and more specifically, PCMH models encompass additional positive outcomes including increased consumer satisfaction, decreased provider burnout, increased access to care, improved patient adherence to treatment recommendations, and reduced stigma toward accessing behavioral health care. Recent federal efforts toward health-care reform including policy changes such as those enacted through the Patient Protection and Affordable Care Act (ACA), as well as systems change reforms like PCMHs, dovetail nicely with the major paradigmatic shifts in health-care service conceptualization and provision occurring throughout PC and behavioral health.
Merritt’s Neurology, Thirteenth Edition

Elan D. Louis, Stephan A. Mayer, and Lewis P. Rowland Wolters Kluwer, Philadelphia, PA, 2015 1402 pages; $179.99 Merritt’s Neurology has been a trusted and comprehensive clinical neurology text for over sixty years, and this latest edition provides many improvements over the 2009 edition. The most noticeable changes are in the opening chapters, which are a quick reference guide for the diagnostic approach to common neurological symptoms. The thirteenth edition opens with a new epidemiological discussion of the burden of neurological disease, which frames the importance of the chapters ahead. The following chapter, “Approach to the Neurologic Patient”, now includes detailed instructions for testing all aspects of neurological function. Included in this chapter are tests for malingering, a particular concern in the neurology patient population. The following section, “Common Problems in Neurology”, has been significantly … jnen{at}pathology.wisc.edu
Treatment modality and timing influence voice outcomes for vocal fold paralysis after thyroidectomy: A recommendation for guarded generalizations from a meta-analysis

This review provides a summary and appraisal commentary on the treatment review by Chen, X., Wan, P., Yu, Y., Li, M., Xu, Y., Huang, P., & Huang, Z. (2014). Types and timing of therapy for vocal fold paresis/paralysis after thyroidectomy: A systematic review and meta-analysis. Journal of Voice, 28(6), 799–808.Source of funding and declaration of interests: Not reported.
1999: How the Economy Came to Resemble the Model

George Stigler (1976, p. 351) wrote that “economists exert a minor and scarcely detectable influence on the societies in which they live.” I don’t believe that is true any longer. In fact, I want to make—and then defend—an audacious claim that directly contradicts Stigler. Since he wrote those words, real-world economies, including ours, have changed in a number of ways that bring them into closer alignment with the pristine model envisioned by economic theory. In this curious sense, life has come to imitate art.
Examining Student Perception of an Open Statistics Book.

The rise of Open Educational Resources (OER) research provides data that Open Textbooks and other forms of OER may be one cost saving approach for college and university students. Yet little research has been conducted around the attitudes and perceptions of the students using these Open Textbooks. This paper examines the perceptions that students have of the different versions of an open statistics textbook used over several years in one community college. Survey results show that students generally had at least as good of an experience using the open textbook compared to traditional textbooks. Suggestions for further research are discussed.
I can so I will, now we must: a creative response to selfie culture

Social Media and Online Social Networks have become increasingly integrated into our every day lives. Digital technologies have progressed from an extension of body to an extension of self. With this integration may come unintended consequences that we are often unaware of. Who would have thought that posting an update on Facebook or browsing your Instagram feed might have an effect on your well-being? The digital world–traditionally–is not a tangible one, but it is most definitely connected to the life experience of those who are part of it. This connection gives it influence, the ability to inform our development as individuals and as a collective. “I can so I will, now we must: A creative response to Selfie Culture” takes a deeper look at this phenomenon. Within this creative response, proof of a new visual language emerges. The users of Instagram are engaged in a universal self-defining system based on posting selfies in repeated categories. Explore the responses in this paper, which seek for ways to find new perspective and heightened awareness of our online activities. The final response is a reflection of knowledge gained from all prior responses. It is a physical interactive cube–controller–used in combination with a visual interface that incorporates aspects of haptic, kinesthetic, visual, and auditory sensory perception as an alternative way to view and interact with selfies. Knowledge is power. If you were more aware of how your interactions online can influence you, your wellbeing, and your sense of self, would you still interact with Online Social Networks in the same way?
Photoluminescence characterization of scintillators for phoswich detectors

The challenge for advanced PET instrumentation is performance optimization in terms of spatial resolution and sensitivity. The phoswich approach, which leads to a better approximation of the interaction point, provides Depth-Of-Interaction information that can significantly reduce parallax error and improve image resolution. In some cases, the scintillator phoswich layers can have not only different decay times but also different characteristics such as light yields, emission spectra, densities, effective atomic numbers, and indices of refraction. Depending on these properties, light interactions between crystals are possible, which may either limit or enhance phoswich functionality. In this paper, we report experiments on the luminescence characteristics of some promising scintillator materials for PET which could be used in a phoswich detector, such as LaBr 3 :Ce, LaCl 3 :Ce, LSO:Ce, GSO:Ce, LPS:Ce, LuYAP:Ce, with an emphasis on investigating excitation/emission spectra, rise times and decay times. For each combination of front and back layer crystals, radioluminescence and photoluminescence spectra were obtained. A Bollinger-Thomas set-up was used to measure luminescence rise and luminescence decay characteristics. Light interactions between scintillator crystals in phoswich detectors were studied and the possibility of measuring convolved light as a result of absorption and re-emission by another crystal layer was experimentally evaluated.
Bracing for Patients With Spinal Tumors

The literature regarding the use of braces in patients with spinal tumors is sparse. In fact, most references on spinal bracing relate to (1) idiopathic adolescent scoliosis (1, 2, 3, 4, 5, 6), (2) osteoporotic compression fractures (7–10), and (3) thoracolumbar spine fractures (11, 12, 13, 14). The role of bracing is much less well defined for the operative and non-operative treatment of spinal tumors. However, they are commonly used in the immediate postoperative period after tumor resection and surgical stabilization to protect both the patient and the integrity of the spinal construct. Although long-term bracing may be successfully used as the sole way of treating spinal instability resulting from tumor, the role of long-term bracing for patients with spinal tumors appears limited. In this setting, with or without the additional use of neoadjuvant chemo- and radiation therapy, biological capacity to achieve spinal fusion may be limited or absent. High pseudoarthrosis rates should, therefore, be expected. If life expectancy is limited to less than 6 mo, braces are frequently applied in one form or another for the purpose of palliation, particularly if surgical treatment is not contemplated or feasible, but spinal instability is of concern.
Intra-arterial Thrombolysis for Extremity Frostbite Decreases Digital Amputation Rates and Hospital Length of Stay

To report outcomes of intra-arterial thrombolysis versus non-thrombolytic management of severe frostbite with respect to digital amputation rates and hospital length of stay (LOS). Seventeen patients with severe frostbite were identified from 2000 to 2017. Eight (47%) patients with mean age of 40 years underwent intra-arterial thrombolysis and served as the treatment group. Nine (53%) patients with mean age of 53 years received non-thrombolytic management and served as the control group. 2/8 (25%) treatment and 3/9 (33%) control patients had underlying vascular comorbidities (p = 0.25). Number of digits at risk, duration of thrombolysis, thrombolytic agents used, digits amputated, hospital LOS, and complications were recorded. Seven upper and nine lower extremities for a total of 80 digits were at risk in the treatment cohort. Eight upper and 12 lower extremities for a total of 100 digits were at risk in the control group. Mean duration of thrombolysis was 26 h. All treatment patients received tissue plasminogen activator in addition to systemic heparin. 4/16 (25%) limbs received intra-arterial alprostadil, 2/16 (13%) received nitroglycerin, and 2/16 (13%) received nicardipine. 12/80 (15%) treatment digits and 77/100 (77%) control digits required amputation (p = 0.003). Average hospital LOS was 14 days in the treatment group and 38 days in the control group (p = 0.011). No major complications occurred in the treatment group; however, 2/9 (22%) patients in the control group required extended hospitalizations secondary to amputation complications. Intra-arterial thrombolysis reduces digital amputation rates and hospital LOS in the setting of severe frostbite.
Higher serum lycopene is associated with reduced prevalence of hypertension in overweight or obese adults

Abstract Introduction Epidemiologic studies suggest an association between overweight/obesity and hypertension. As a middle mediator between overweight/obesity and hypertension, serum uric acid plays an important role in the renin-angiotensin-aldosterone system. As a natural antioxidant, lycopene can effectively inhibit the angiotensin-converting enzyme activity and attenuate oxidative stress induced by angiotensin-II. Therefore, the objective of this study was to determine whether lycopene could have an association with lower levels of hypertension in individuals who are overweight and obese. Methods A total of 8556 adult participants with BMI ≥ 25 from the National Health and Nutrition Examination Survey 2001–2006 were used to examine the associations among serum uric acid, serum lycopene and hypertension in this study. Results It was found that there was a significant positive association between serum uric acid and hypertension while there was a significant inverse association between serum lycopene and hypertension. Furthermore, there was a significant association between the ratio of serum lycopene to serum uric acid and hypertension in adults who are overweight/obese. Conclusions Therefore, lycopene has a significant association with lower levels of hypertension in individuals who are overweight and obese.
Abstract TMP49: Depressive Symptoms After Stroke are Linked Longitudinally between Stroke Survivors and Their Family Caregivers

Background: Multiple previous investigations have documented persistent elevations in depressive symptoms after stroke for stroke survivors and for family caregivers. However, relatively few studies have examined both groups simultaneously, and none have tested for possible predictive linkages in longitudinal analyses. Methods: We collected interview data from 248 stroke survivors and their primary family caregivers who were enrolled in the Caring for Adults Recovering from the Effects of Stroke (CARES) project. CARES is an ancillary study to the national REasons for Geographic and Racial Differences in Stroke (REGARDS) study. Stroke survivors and caregivers were interviewed at 9-, 18-, 27- and 36-months after an adjudicated stroke event. Measures administered to both groups included the 20-item Center for Epidemiological Studies Depression Scale (CESD) and the 12-item Short Form Health Survey (SF-12) of health-related quality of life. Cross-lagged panel analyses were used to investigate linkages between stroke survivors and caregivers over time on these measures. Results: Clinically significant levels of depressive symptoms, as defined by a score of 16 or more on the CESD, were found for 17.0% of the stroke survivors and 13.7% of the caregivers at 9-months after stroke. Longitudinal models revealed that high stroke survivor depressive symptoms at 9-months post-stroke predicted increases in caregiver depressive symptoms at 18-months post-stroke (standardized adjusted regression coefficient = 0.18, p = 0.003). No longitudinal predictive effects were found for caregiver depressive symptoms on stroke survivor outcomes or for the SF-12 measures. Conclusions: Clinically significant levels of depressive symptoms were relatively rare 9-months after stroke in this population-based sample of stroke survivors and family caregivers. Stroke survivor depressive symptoms longitudinally predict caregiver depressive symptoms, but caregiver well-being was not found to longitudinally predict stroke survivor depression or quality of life. Treating elevated depressive symptoms in stroke survivors may also improve caregiver well-being.
Teaching in the Mix: Turntablism, DJ Aesthetics and African American Literature.

AbstractLeveraging the aesthetic turn in hip-hop scholarship, this article examines how some of the goal-directed and compositional techniques of DJs can be used to redesign and remix African American literature courses. Specifically, we focus on drops and blends, two moves evident among DJs and turntablists in hip-hop culture. Anchoring our analysis to DJs and what they do with records, we also conceptualise the classroom and curriculum as a mix with various media, samples and layers that afford the instructor different pedagogical opportunities. Overall, we argue these DJ moves are not simply surface-level descriptions of course design and execution, but rather they entail different ways of thinking about course design and execution when properly understood from their hip-hop context.
“Who Would Find You?”: A Question for Working with Suicidal Children and Adolescents

This paper discusses the rationale, employment, and benefits of a particular question, “Who would find you?”, within the assessment of suicidal youngsters. The question helps identify salient interpersonal conflicts and supports in the young person's life, and indicates the direction for reparative and preventive interventions. For the young person, the question has the potential to release emotions, increase cognitive awareness of the reality of suicide, and generate a sense of hope. For the practitioner, it can increase skill and build confidence in the carrying out of a daunting clinical task.
Cutover: Getting Ready for the Launch

In any divestiture or separation, deal execution is critical to achieving Day 1 success. Deal execution often draws the most attention from leadership due to its associated risks and impact on shareholder value. Cutover forms the crux of deal execution.
V.L.F. PROPAGATION

The T.M. and T.E. modes excited by horizontally and vertically polarized line sources are investigated for homogeneous, exponentially varying and composite daytime and nighttime ionosphere models. Ion effects are investigated for several models of a perturbed ionosphere. Because of ionospheric anisotropy, the vertically polarized source excites also T.M. field components with wave numbers corresponding to T.E. modes; and a horizontally polarized source excites T.E. fields corresponding to T.M. modes, particularly for the higher frequencies at nighttime and for propagation towards west. Among the field components tangential to the ground surface, T.M. fields tend to dominate with the exception of T.E. modes at daytime and for lower frequencies also at night. T.M. modes dominate in the nighttime mode sum (or interference pattern) for propagation towards east, but the two lower T.E. modes contribute significantly if propagation is towards west. For higher frequencies at nighttime, the ratio of T.E. to T.M. field components may change for various directions of propagation in such a way that a quasi-T.E. (or T.M.) mode appears to change into a quasi-T.M. (or T.E.) mode.
Clinical Impact of Chronic Aortic Regurgitation in Asymptomatic Patients with Native Aortic Valve Stenosis

Background: The pathologic processes of aortic regurgitation (AR) and aortic stenosis (AS) can affect the rate of progression to symptoms differently, and insight into the management of mixed aorti...
Extraversion, neuroticism, and the electrocortical response to monetary rewards in adolescent girls

Abstract Affective personality traits, such as extraversion and neuroticism, are associated with individual differences in reward system functioning. The reward positivity (ΔRewP) is an event-related potential (ERP) component that indexes sensitivity to reward, and can be elicited by feedback indicating monetary gains relative to losses. In a sample of 508 adolescent girls, the current study examined the relationship between extraversion, neuroticism, and their respective facets and the ΔRewP. Results indicated an Extraversion × Neuroticism interaction, such that greater extraversion was associated with an increased ΔRewP, but only in the context of low neuroticism. This association was primarily due to the extraversion facet positive emotionality—high levels of positive emotionality were associated with an increased ΔRewP, but only in the context of low neuroticism. In addition, increased neuroticism diminished the age-related increase in the ΔRewP. The current study suggests that both extraversion and neuroticism are associated with reward system function in adolescence.
Contextual Constraints and Choices: Strategic Identity Management among LGBTQ Youth.

Lesbian, gay, bisexual, transgender and queer (LGBTQ) young people's identity management impacts their well-being, yet little is known about how distinctive social environments shape their identity...
Ruptures of War: Shame and Symbolic Violence in Post-Conflict Acholiland

Up until 2006, conflict between the Lord’s Resistance Army (LRA) and the Ugandan government disrupted lives of people living in northern Uganda. The conflict has challenged ethnic identities, particularly that of the Acholi. Moreover, the disruptions of war have challenged the way my Acholi informants define themselves as human beings and members of society. In the following ethnography, I argue that not only have my informants experienced symbolic violence undermining their sense of honor and worthiness at the hands of the Ugandan government and the LRA, but that the shame they feel after the conflict also commits symbolic violence against themselves. The struggle for honor, dignity, worthiness, and legitimacy has been internalized, and they inhabit psychologically both the position of the dominant and the dominated. For my informants, shame is an undermining force that rattles the way they make sense of their world, affirm their identities, and justify their existence.
Hope and Possibility: Advancing an Argument for a Habermasian Perspective in Educational Administration

The emergence of postmodernism has stimulateddiscourse on the potential for using reason tocreate a just society. The discourse hascaused confusion and dissension in the field ofeducational administration as scholars seek tofind a means to blend concepts inherent in themodern and postmodern. The works of JurgenHabermas provide a means of dealing with thisdilemma and have some specific applications tothe practice of educational administration.
Computational Model of Porous Media Using True 3-D Images

Thermally conductive foams are being developed for many engineering applications; and there is a need to develop analytical models to predict the thermal properties of such porous media. Most of the current models are based on volume averaging techniques, and often assume simple, ideal shapes for the pore geometry. The method described in this chapter focuses on modeling the thermal and flow properties of foams on the basis of its true microstructure. The approach is to take a three dimensional solid model of a real foam, obtained by imaging techniques, and use it as the basis for the numerical solution of the transport phenomena. This is a micro-model, in which the thermal phenomena are modeled at the pore level of the foam. The model is computationally intensive, as can be expected; but it does not require semi-empirical or experimentally derived constants such as permeability to derive a solution. By incorporating the effect of the true pore geometry on the thermal transport and fluid flow in the foam, this model is able to determine the thermal conductivity, permeability, friction factor and heat transfer coefficients. Graphitic carbon and silicon carbide foams are used in this study, but the approach that is described is quite general and can be applied to other porous media; it may also be applied to composites that contain phases with distinct boundaries at the micro-level.
The Prosodic Marionette: a method to visualize speech prosody and assess perceptual and expressive prosodic abilities.

Abstract Speech technology applications have emerged as a promising method for assessing speech-language abilities and at-home therapy, including prosody. Many applications assume that observed prosody errors are due to an underlying disorder; however, they may be instead due to atypical representations of prosody such as immature and developing speech motor control, or compensatory adaptations by those with congenital neuromotor disorders. The result is the same – vocal productions may not be a reliable measure of prosody knowledge. Therefore, in this study we examine the usability of a new technology application to express prosody knowledge without relying on vocalizations using the Prosodic Marionette (PM) graphical user interface for artificial resynthesis of speech prosody. We tested the ability of neurotypical participants to use the PM interface to control prosody through 2D movements of word-icon blocks vertically (fundamental frequency), horizontally (pause length), and by stretching (word duration) to correctly mark target prosodic contrasts. Nearly all participants used vertical movements to correctly mark fundamental frequency changes where appropriate (e.g., raised second word for pitch accent on second word). A smaller percentage of participants used the stretching feature to mark duration changes; when used, participants correctly lengthened the appropriate word (e.g., stretch the second item to accent the second word). Our results suggest the PM interface can be used reliably to correctly signal speech prosody, which validates future use of the interface to assess prosody in clinical and developmental populations with atypical speech motor control.
Anniversary review: Antithyroid drug therapy: 70 years later

The thionamide antithyroid drugs were discovered in large part following serendipitous observations by a number of investigators in the 1940s who found that sulfhydryl-containing compounds were goitrogenic in animals. This prompted Prof. Edwin B Astwood to pioneer the use of these compounds to treat hyperthyroidism in the early 1940s and to develop the more potent and less toxic drugs that are used today. Despite their simple molecular structure and ease of use, many uncertainties remain, including their mechanism(s) of action, clinical role, optimal use in pregnancy and the prediction and prevention of rare but potentially life-threatening adverse reactions. In this review, we summarize the history of the development of these drugs and outline their current role in the clinical management of patients with hyperthyroidism.
Unique Features of the Antibody Problem

Information obtained in the serologic and structural studies described in the previous chapters revealed several striking features of antibodies and the genes that encode them. First of all, it became obvious that there was no known precedent for the immune system. No other biologic process requires the synthesis, on demand, of numerous large molecules with diverse binding properties. There have been attempts to equate olfaction or the general function of the nervous system to the immune system but these are not appropriate comparisons because these systems are not known to use large numbers of structurally distinct proteins in their functionings. Other multigene families such as those encoding ribosomal RNA or histones are required to carry out fixed functions rather than maintain the ability to generate diversity. Although there are a number of similarities between immunoglobulins and proteins encoded at the major histocompatibility complex, the analogy does not include a similar type of diversity.
A metric suite to analyse strength of modularised ontologies

Ontologies are used to acquire, represent, and process information in various domains. Ontology developed has to be validated and verified for its quality. Measuring the quality of ontology helps to make decisions when sharing, using or reusing ontology. One of the ways of measuring the ontology is to evaluate using metrics. The classes, instances and relationships of ontology can be represented in graph with nodes and leafs. Analysing the graph of ontology decisions can be made regarding the quality of ontology. Cohesion measures the relatedness, connectivity and interdependence of ontology. Cohesion shows the degree of relatedness between different entities. When the entities of ontology are highly related there is a strong cohesion value. The design quality of ontology can be evaluated using cohesion. The results of cohesion when used with measures of other attributes can be used for the modularisation of ontology. This paper proposes a metric suite to calculate the strength of ontology. The metric suite proposed can be used to evaluate the quality of ontology. The derived metric suite is theoretically validated. The results indicate that the metric suite works well and gives the strength of modularised ontology.
If a tree falls in an urban stream, does it stick around? Mobility, characteristics, and geomorphic influence of large wood in urban streams in northeastern Ohio, USA

Abstract Large wood influences geomorphological, ecological, and biogeochemical functions of streams, but in urban areas it is also considered an unaesthetic hazard. Quantifying the abundance and mobility of in-stream wood along an urban intensity gradient, and understanding the relationship between wood dynamics and stream reach, network, and watershed characteristics allows for a stronger understanding of the potential benefits and hazards of wood in urban streams. Repeat wood surveys were conducted at 11 stream reaches in the Cleveland, Ohio area, where wood removal is not practiced and forested riparian zones exist. Study reaches span a gradient of impervious surface cover and extent of the stream network with a forest buffer. Channel morphology and sediment size were also measured. Stream hydrology does not change when imperviousness is 12–40% in this region, so quantification of impervious surfaces stands in for a broader suite of urban impacts. Wood abundance decreases – and mobility increases – as urban intensity in the watershed and along the stream network increases. Jams become smaller and less stable, but the size and orientation of individual wood pieces do not change along an urban gradient. Over the 6-month study period, wood mobility exceeded 100% in some of the most urbanized streams and transport distances are inferred to be on the order of 100s of meters. There was a positive correlation between jam spacing and pool spacing, and finer sediment sizes occurred in some wood-associated deposits, but overall geomorphic effects are limited. Where reaches are confined, wood abundance is suppressed, but impervious surfaces and the extent of forest along the stream network are stronger predictors of wood dynamics than reach scale characteristics. These results emphasize the importance of situating understanding of reach-scale wood dynamics in the context of larger scale phenomena.
Monetary growth and wealth inequality

Abstract We construct a global panel data set to examine the relationship between monetary growth and wealth inequality. Dynamic panel estimates suggest that both overall and inherited wealth inequality increase with growth in the base money supply. These results hold for countries with at least one billionaire and for OECD countries.
Exome sequencing of Finnish isolates enhances rare-variant association power.

Exome-sequencing studies have generally been underpowered to identify deleterious alleles with a large effect on complex traits as such alleles are mostly rare. Because the population of northern and eastern Finland has expanded considerably and in isolation following a series of bottlenecks, individuals of these populations have numerous deleterious alleles at a relatively high frequency. Here, using exome sequencing of nearly 20,000 individuals from these regions, we investigate the role of rare coding variants in clinically relevant quantitative cardiometabolic traits. Exome-wide association studies for 64 quantitative traits identified 26 newly associated deleterious alleles. Of these 26 alleles, 19 are either unique to or more than 20 times more frequent in Finnish individuals than in other Europeans and show geographical clustering comparable to Mendelian disease mutations that are characteristic of the Finnish population. We estimate that sequencing studies of populations without this unique history would require hundreds of thousands to millions of participants to achieve comparable association power. Exome-wide sequencing studies of populations in Finland identified 26 deleterious alleles associated with 64 quantitative traits that are clinically relevant to cardiovascular and metabolic diseases.
Remote estimation of overwintering home ranges in an elusive, migratory nocturnal bird.

Due to a long running research bias toward the breeding season, there are major gaps in knowledge on the basic nonbreeding ecology of many species, preventing a full-annual cycle focus in ecology and conservation. Exacerbating this problem is the fact that many species are extremely difficult to detect outside of breeding. Here, we demonstrate a partial solution to this problem by using archival GPS tags to examine the overwintering ecology of a migratory nocturnal bird, the eastern whip-poor-will (Antrostomus vociferous). We deployed tags on 21 individuals and were able to recover 11 (52%) one year later. Tags collected high precision (approx. 10 m) points throughout the nonbreeding period. With continuous time movement models, we used these data to estimate overwintering home ranges. All individuals exhibited at least one bounded home range during this phase of the annual cycle, three of eleven had two wintering locations, and home range area ranged from 0.50 to 10.85 ha. All overwintering home ranges contained closed-canopy forest land cover (42%-100%), and no other land cover type represented >40% of any home range. We found some evidence, with caveats, that total edge within the landscape surrounding the home range was negatively related to home range area. The prevalence of contiguous closed-canopy forest cover in overwintering home ranges contrasts with apparent breeding habitat preferences, which includes clear-cuts and other, more open, habitats. This study is the first to reveal key aspects of overwintering space use in this species by using archival GPS to overcome both logistical and methodological limitations. Expanded use of such technology is critical to gathering basic ecological and distributional data, necessary for achieving a more complete understanding of full-annual cycles of animal populations.
Critical Rhetoric| The Critique of Domination and The Critique of Freedom: A Gramscian Perspective — Commentary

This article recounts the significance of Raymie McKerrow’s article “Critical Rhetoric: Theory and Praxis” for scholars in the field of communication studies. In contrast to the Foucauldian stance on domination and freedom put forward by McKerrow, I argue that the Marxist and antifascist activist Antonio Gramsci offers an account of domination and freedom in the theory of hegemony that is internally consistent. In addition to its coherence, hegemony theory is rooted in historical materialist practice that urges challenges to capitalism as a system rather than exercising contingent judgments without a clear goal, or telos. Gramsci’s “pessimism of the intellect, optimism of the will” is an urgent corrective to the “critique of freedom” and poststructuralist thought more generally in the present political moment.
Reevaluating the Need for Routine Coverage of the Left Subclavian Artery in Thoracic Blunt Aortic Injury.

Background Thoracic endovascular aortic repair (TEVAR) is the treatment of choice for thoracic blunt aortic injury (TBAI). A 20 mm proximal seal zone is recommended based on aneurysmal disease literature which often results in coverage of the left subclavian artery (LSA). The aim of this study was to analyze our experience with TEVAR for TBAI and evaluate whether 20 mm is required to achieve successful remodeling. Methods This is a single-center, retrospective study of all consecutive patients who received a TEVAR for treatment of moderate and severe TBAI between April 2014 and November 2018. Three-dimensional software reconstruction was used for computed tomography (CT) scan centerline measurements. Outcomes included technical success, need for reinterventions, and immediate and long-term aortic-related complications. Results Sixty-one patients underwent TEVAR for TBAI during the study period. Twenty-eight (46%) patients underwent LSA coverage with an average distance from the LSA to the injury of 6.4 mm (0–15.1 mm). Of the 33 (54%) patients who did not undergo coverage of the LSA, 22 patients (66%) had less than 20 mm of proximal seal zone. The mean distance from the LSA to injury in this group was 16.6 mm (7.9–29.5 mm). None of the patients with LSA coverage developed ischemic symptoms, and an average decrease in left arm systolic blood pressure of 24.8 mm Hg (0–62 mm Hg) was noted versus the right arm. There was no aortic-related mortality in either group. Follow-up CT scans revealed excellent remodeling. Conclusions Immediate outcomes of TEVAR for TBAI with LSA coverage are well tolerated; however, the long-term sequela of LSA coverage is unknown. Exclusion of the injury and excellent remodeling appear to occur with less than 20 mm of proximal seal, and perhaps more attention should be made to preservation of the LSA.
Electrifying the Beat: Rhythm Guitar Performances of Keith Richards, Joan Jett, and Nile Rodgers

By closely studying three key musicians—Keith Richards, Joan Jett, and Nile Rodgers—I argue that rhythm guitar playing, while maintaining some of rock music’s appropriation of blackness and coding ...
Russia, the former Soviet republics, and Europe since 1989: transformation and tragedy

Graney admirably and single-handedly undertakes a very ambitious project on a truly big topic. Her manuscript will be gladly received by many scholars in the post-Soviet studies field as we finally...
Novel and combination therapies for polycythemia vera and essential thrombocythemia: the dawn of a new era.

Essential thrombocythemia (ET) and polycythemia vera (PV) belong to the BCR-ABL1-negative myeloproliferative neoplasms and are characterized by the clonal proliferation of hematopoietic stem and pr...
Need for Additional Glaucoma Surgery and Complications Following Glaucoma Drainage Device Surgery.

Prcis In this longitudinal study of patients with open-angle (OAG), pseudoexfoliative (PXE), or neovascular glaucoma (NVG) receiving glaucoma drainage devices (GDD), posttube cumulative rates of reoperation, corneal graft, and visually threatening complications (VT-complications) increased beyond 5 years and were not significantly affected by glaucoma type. Purpose To study the need for additional glaucoma surgery and development of complications after first GDD surgery in eyes with primary OAG, PXE, or NVG glaucoma. Patients and methods There were 306 eyes with OAG (n=185), PXE (n=60), or NVG (n=61) glaucoma who received a first GDD between 1996 and 2017. Outcomes including glaucoma reoperation, corneal graft procedure, and VT-complications after GDD were measured. Kaplan-Meier analysis was used to compare cumulative rate of reaching outcomes over time after GDD placement among the 3 glaucoma groups. Results When comparing the OAG, PXE, and NVG groups, there were no significant differences in post-GDD cumulative rates of reoperation (P=0.33), corneal graft (P=0.26), or VT-complications (P=0.65) over time. For all eyes, the overall cumulative rates for each outcome measure increased beyond 5 years, and specific Kaplan-Meier rates (5-y, 10-y) included: reoperation (16%, 25%), corneal graft (6%, 12%), VT-complications (9%, 14%). When comparing specific GDDs, the Ahmed FP7 had a higher cumulative reoperation rate over time compared with the Baerveldt 350 (P=0.019). Conclusion Glaucoma type did not significantly affect post-GDD cumulative rates of reoperation, corneal graft, and VT-complication among the OAG, PXE, and NVG groups. For all eyes, cumulative rates of reoperation, corneal graft, and VT-complications increased beyond 5 years. The Ahmed FP7 had a significantly higher cumulative reoperation rate compared with the Baerveldt 350 over time.
Preventing illegal logging

Abstract This paper presents ideas and strategies to prevent illegal logging of timber. Globally, illegal logging is a substantial problem. While the exact amount of timber harvested illegally is unknown, the problem is estimated to cost USD$30–100 billion annually. Criminological theories suggest intervention mechanisms that could either prevent or severely limit illegal logging in the forests. Utilizing situational crime prevention techniques, certain strategies for prevention on the ground include signage indicating boundaries, gates lining access roads, and checkpoint locations. Transparency strategies include remote sensing, wood tracking operation standards and procedures, and independent certification. Additionally, forestry law enforcement, forestry management, and local communities must be encouraged to actively combat the problem of illegal logging.
Dialectical Behavior Therapy for Early Life Trauma

Co-occurring borderline personality disorder (BPD) with posttraumatic stress disorder (PTSD) and complex posttraumatic stress disorder (CPTSD) are severe and disabling psychiatric sequelae of early trauma. While the emergence of evidence-based treatments such as dialectical behavior therapy (DBT) and prolonged exposure (PE) improved treatment for BPD and PTSD individually, treatment gaps remain for individuals with co-occurring BPD and PTSD as well as CPTSD. DBT prolonged exposure (DBT+PE) and DBT for PTSD (DBT-PTSD) combine skills training to enhance emotional, behavioral, interpersonal, and attentional stability with prolonged exposure to support engagement and processing required for effective PTSD treatment. DBT+PE improves PTSD remission rates and suicide rates to a greater degree than standard DBT. DBT-PTSD shows higher rates of remission from PTSD and reliable recovery than cognitive processing therapy in patients with BPD symptoms and complex PTSD related to severe and chronic childhood physical and sexual abuse. DBT+PE requires the completion of standard DBT and adequate management of suicidality and self-harm to foster safety in tolerating the intense emotions expected in prolonged exposure. DBT-PTSD provides psychoeducation about trauma and its effects, promoting mindfulness, compassion, anti-dissociation, and emotion regulation skills training prior to exposure treatment. While DBT+PE follows standard prolonged exposure procedures, DBT-PTSD focuses on processing primary trauma-related emotions such as powerlessness, fear, and disgust, as well as subsequent traumatic invalidation encountered when attempts were made to share the traumatic experience with others. Both treatments also emphasize rebuilding life outside of treatment following exposure, using DBT skills and a focus on goals and values to provide an alternative path to a corrective experience to recover from PTSD.
Depression and anxiety symptoms are related to pain and frailty but not cognition or delirium in older surgical patients.

Objective In community dwelling older adults, depression and anxiety symptoms can be associated with early cognitive decline. Symptoms of depression and anxiety are common in older adults prior to surgery. However, their significance is unknown. Our objective was to determine whether preoperative depression and anxiety symptoms are associated with postoperative cognitive decline (POCD) and in-hospital delirium, in older surgical patients. Methods We conducted a secondary data analysis of postoperative cognitive dysfunction in a cohort study of patients 65 and older undergoing elective noncardiac surgery. We used the Hospital Anxiety and Depression Scale (HADS) to screen for depression and anxiety symptoms at a home visit prior to surgery and 3 months after surgery. Patients with a history of psychiatric (major depressive disorder, bipolar disorder, and schizophrenia) or neurologic disorder (Parkinson's disease and stroke) were excluded from the parent study. Results Out of the 167 patients, 9.6% (n = 16) reported significant depressive symptoms and 21.6% (n = 36) reported significant anxiety symptoms on preoperative screening. There was no association between preoperative or new-onset postoperative depression and anxiety symptoms and the incidence of delirium or POCD three months after surgery. Patients with preoperative depressive symptoms had higher preoperative pain (scores 69 vs. 35.7, p = .002) and frailty (56 vs. 14.6, p Conclusion In our cohort, we did not detect an association between preoperative depression and anxiety symptoms and neurocognitive disorders. Preoperative depression and anxiety symptoms were related to physical pain and frailty. Taken together, these suggest that in patients without a formal psychiatric diagnosis, preoperative depression and anxiety symptoms are related to physical state rather than a harbinger of early cognitive decline. Future studies are needed to understand the nature of the relationship between depression and anxiety symptoms and physical state in surgical patients.
Male pseudohermaphroditism with female chromosomal constitution.

An infant with ambiguous genitalia was found to have infantile testicles bilaterally with no ovarian tissue. The sex chromatin pattern was positive, however, and chromosomal analysis of leukocytes, skin, and gonad revealed a normal female karyotype with no evidence of the presence of a Y chromosome.
Alternatives, traditions, and diversity in agriculture.

This review essay examines several recentbooks about agriculture, including two books on thelinks between cultural and biological diversity intraditional agriculture, two books on the US farmcrisis, and a collected volume examining globalaspects of agricultural restructuring andsustainability. Finally, a history of ``alternative''agriculture provides a framework for thinking aboutthe ways the different cases shed light on the complexrelations between tradition and innovation inagriculture. A historical perspective highlights theextent to which ``alternative'' is a relative term. Themonocrop, ``factory'' mode that dominate US agriculturetoday certainly differs from what has characterizedfarming for most of history and in most of the world.Small-scale, more or less organic, diversified farms,which appear so ``alternative'' in the present context,have until lately counted as the norm, here andelsewhere. These books also highlight both the dangersof the currently dominant industrial agriculture andthe potential for genuine alternatives.
A Thin LiPb/Be Helium Cooled Blanket for MINIMARS: Neutronics Analysis

This work presents a thin blanket design for the commercial tandem mirror reactor MINIMARS using the reactor parameters to date. Future studies may call for minor changes in the parameters to incorporate the idea of central cell wall stabilization and to achieve the inherent safety goal. Although the study was carried out for a 17Li-83Pb system, the trends observed here hold true for other breeding materials. Recent studies for minimizing blanket thickness used idealized blankets with semicontinuously varying composition and no allowance for cooling. Here we present a realistic thin blanket design that satisfies all requirements of neutronics, safety, thermal-hydraulics, and mechanical design.
Newborn Screening for Glutaric Aciduria-II: The New England Experience

Newborn screening (NBS) using tandem mass spectrometry (MS/MS) permits detection of neonates with Glutaric Aciduria-Type II (GA-II). We report follow-up of positive GA-II screens by the New England Newborn Screening Program.