cssi/SciSciGPT-SciSciNet huggingface dataset:
Maternal Dietary Protein Intake Influences Milk and Offspring Gut Microbial Diversity in a Rat ( Rattus norvegicus) Model

Historically, investigators have assumed microorganisms identified in mother's milk to be contaminants, but recent data suggest that milk microbiota may contribute to beneficial maternal effects. Microorganisms that colonize the gastrointestinal tracts of newborn mammals are derived, at least in part, from the maternal microbial population. Milk-derived microbiota is an important source of this microbial inocula and we hypothesized that the maternal diet contributes to variation in this microbial community. To evaluate the relationship between a mother's diet and milk microbiome, we fed female rats a low- or high-protein diet and mated all individuals. Milk and cecal contents were collected from dams at peak lactation (14-day post-partum), and the bacterial composition of each community was assessed by 16S rRNA gene amplicon sequencing. Our findings revealed higher dietary protein intake decreased fecal microbial diversity but increased milk microbial and pup cecum diversity. Further, the higher dietary protein intake resulted in a greater abundance of potentially health-promoting bacteria, such as Lactobacillus spp. These data suggest that dietary protein levels contribute to significant shifts in the composition of maternal milk microbiota and that the functional consequences of these changes in microbial inocula might be biologically important and should be further explored.
Mind, Culture, and Art Theory: Approaches to Psychology of Art

This article is a critical review of the intellectual relations between History of Art and a field of psychology called "Psychology of Art". Psychology of Art studies the art as a product of human mind from the creator, the receiver and the artistic object’s perspective. The analysis of the ideas behind both artistic productions and society that describes and retains them have undergone various stages of development since the late nineteenth century. This field of study involves art theorists, critics and historians, as well as psychoanalysts and psychologists who have written about the relations among art, mind and culture. The initial contributions of psychoanalysts such as Freud, Jung and Lacan disputed the first critical positions to an opening field. Year later, Kris’ writings, and theories of Psychology of Style and the School of Gestalt were crucial for the future of the discipline. Vygotsky's great contribution to the definition of the Psychology of Art and its boundaries and Gombrich’s studies devoted to the psychology of visual representation, were the natural continuation of previous approaches, as well as Gardner’sand Vigouroux’s works in the past decades. This historical overview shows how the Psychology of Art has been present in many psychological schools of though at the same time, how it is constantly present nowadays and needs a continuity in line with the latest psychological and theoretical trends.
Automorphism group actions in complex analysis

Abstract In this paper we describe the subject of automorphism groups of domains in complex space. This has been an active area of research for fifty years or more, and continues to be dynamic and developing today. We discuss noncompact automorphism groups, the Bun Wong/Rosay theorem, the Greene/Krantz conjecture, semicontinuity of automorphism groups, the method of scaling, and other current topics. Contributions from geometers, Lie theorists, analysts, and function theorists are described.
Emerging novel therapeutic agents for the treatment of patients with prurigo nodularis.

Dear Editor,Prurigo nodularis (PN) is an inflammatory skin disease characterized by intractably itchy nodules that often become excoriated and can ulcerate. PN has a significant burden of disease, ...
Terahertz digital holographic imaging

This tutorial describes the application of digital holography to the terahertz spectral region and demonstrates how to reconstruct images of complex dielectric targets. Using highly coherent terahertz sources, high-fidelity amplitude and phase reconstructions are achieved, but because the millimeter-scale wavelengths approach the decimeter-sized targets and optical components, undesirable aperture diffraction degrades the quality of the reconstructions. Consequently, off-axis terahertz digital holography differs significantly from its visible light counterpart. This tutorial addresses these challenges within the angular spectrum method and the Fresnel approximation for digital hologram reconstruction, from which the longitudinal and transverse resolution limits may be specified. We observed longitudinal resolution (λ/284) almost two times better than has been achieved with visible light digital holographic microscopy and demonstrate that submicrometer longitudinal resolution is possible using millimeter wavelengths for an imager limited ultimately by the phase stability of the terahertz source and/or receiver. Minimizing the number of optical components, using only large reflective optics, maximizing the angle of the off-axis reference beam, and judicious selection of spatial frequency filters all contribute to improve the quality of the reconstructed image. As in visible wavelength analog holography, the observed transverse resolution in terahertz digital holography is comparable to the wavelength but improves for features near the edge of the imaged object compared with features near the center, a behavior characterized by a modified description of the holographic transfer function introduced here. Holograms were recorded by raster scanning a sensitive superheterodyne receiver, and several visibly transparent and opaque dielectric structures were quantitatively examined to demonstrate the compelling application of terahertz digital holography for nondestructive test, evaluation, and analysis.
Chapter 1 – Gravity

Publisher Summary This chapter provides an overview of gravity. It presents an experiment with a force that is gravity and discusses the results of this experiment. If a particle (P) of mass (m), situated at height (h) above ground, is dropped from a position of rest, its height x above ground can be measured every Ιt seconds as it falls. The chapter focuses on the conservation of energy because of the intimate relationship between energy conservation and computational stability. The physical significance of Newtonian mechanics is characterized by the laws of conservation of energy, linear momentum, angular momentum, and by symmetry, that is, by the invariance of its laws of motion under fundamental coordinate transformations.
Retrospective Review of Pregnant Patients Presenting for Evaluation of Acute Neurologic Complaints.

Study objective Data suggest an increase in neurologic-related hospitalizations during pregnancy. It is crucial for health care providers to develop effective strategies to evaluate this young, generally healthy cohort of patients for whom missed neurologic diagnoses can have devastating results. We aim to describe the epidemiology of this high risk patient population by investigating exam findings, imaging studies, and clinical outcomes of pregnant women presenting to the emergency department (ED) with acute neurologic complaints. Methods We conducted a 7-year retrospective chart review of pregnant patients presenting with neurologic chief complaints to the emergency department of an urban tertiary academic medical center in the northeastern United States. We investigated examination findings, imaging studies, and clinical outcomes. Results Between January 1, 2010, and May 31, 2017, 205 pregnant patients presented to the ED with a neurologic chief complaint. The majority of patients had a normal neurologic examination result. Patients with an abnormal examination result were not more likely to have clinically significant imaging findings. Within our population, 28% underwent imaging, and noncontrast magnetic resonance imaging was the most common modality. Five patients had clinically significant imaging findings. Specifically, 3.3% of patients with abnormal examination result had significant findings and 2.3% of those with a normal examination result had significant findings. A minority of the patients with a visit resulting in discharge (9.8%) returned to the ED within a 7-day period. None required additional neuroimaging. Conclusion To our knowledge, our study is unique in that it incorporated all neurologic complaints. Headache was the most common complaint, followed by dizziness and seizures. Most of the headaches were related to first-trimester migraines. There was a high incidence of imaging used in clinical practice even when there was a normal neurologic examination result. A normal examination result does not adequately exclude serious intracranial pathology, and diagnostic vigilance is justified.
Modeling atomic layer deposition process parameters to achieve dense nanocrystal-based nanocomposites

Atomic layer deposition (ALD) is a technique capable of depositing conformal coatings in highly tortuous 3D nanostructures. One configuration that has attracted attention is nanocrystal (NC) based nanocomposite films, whereby a 3D network of randomly packed nanocrystals is infilled via ALD to yield a dense nanocomposite. In this work, we demonstrate criteria for predicting three important thermal ALD process parameters necessary to completely infill 3D NC networks: cycle number, precursor pulse time, and purge time. A description of representative pore geometry is developed using parameters of the film comprised of nanocrystals before infill, specifically NC diameter, NC volume fraction, and film thickness. This geometric description allowed for prediction of required precursor pulse times to saturate the NC film surface. A finite-difference model of water vapor transport during purging revealed that desorption kinetics can be used to predict purge times required to achieve complete infill. The model predictions show good agreement with experiments carried out by infilling films comprised of GaN NCs with ZnO by the diethylzinc/water process and films comprised of Al2O3 NCs with Al2O3 by the trimethylaluminum/water process.
Valproic Acid-Induced Thrombocytopenia-Related Spontaneous Systemic Bleeding

BACKGROUND Valproic acid is utilized for the management of various disease states, but coagulation changes, such as thrombocytopenia, can limit use. Valproic acid is a highly protein-bound drug. Serum levels of 50-100 mcg/mL are considered therapeutic, with minimal risk of toxicity when maintained within the recommended therapeutic index. We present a case of valproic acid-induced thrombocytopenia associated with spontaneous systemic bleeding. CASE REPORT A 57-year-old woman with history of generalized anxiety disorder and choreiform movements presented to the Emergency Department with 1 day of oral and vaginal bleeding. The patient had been started on valproic acid for choreiform movements 3 weeks prior. On physical exam, the patient was noted to have atraumatic contusions and ecchymosis. A CT head revealed left temporal frontal subdural hematoma (4.5 mm), acute subdural hematoma along the posterior aspect of the interhemispheric falx (5 mm), mass effect on the right lateral ventricle, and an approximately 3 mm right-to-left midline shift. Laboratory testing was notable for platelets 4000/μL, hemoglobin 7.3 g/dL, hematocrit 23.1%, fibrinogen 467 mg/dL, and valproic acid random level 26.3 μg/mL. Thromboelastography releveled normal values except for a decreased maximum amplitude of 33.4 mm. CONCLUSIONS Although the clinical relevance is still debated, few case reports of significant bleeding related to valproic acid-induced thrombocytopenia exist. To the best of our knowledge, this is the first case report of spontaneous systemic bleeding due to valproic acid-induced thrombocytopenia in the setting of normal fibrinogen levels. Furthermore, this report demonstrates the potential risk of thrombocytopenia with subtherapeutic VPA levels.
Method of intra-arterial drug administration in a rat: Sex based optimization of infusion rate.

Abstract Background Endovascular thrombectomy is the process of removing a blood clot and re-establishing blood flow in patients with emergent large vessel occlusion. The technique provides an opportunity to deliver therapeutics directly to the site of injury. The intra-arterial (IA) route of drug administration in the mouse was developed to bridge the gap between animal stroke treatments and clinical stroke therapy. Here, we adapted the IA method for use in rats, by investigating various flow rates to optimize the IA injection through the internal carotid artery (ICA). Methods Male and female Sprague-Dawley rats (∼4 months of age) were subjected to placement of micro-angio tubing at the bifurcation of the common carotid artery for injection into the ICA. We evaluated a range of infusion rates of carbon black ink and its vascular distribution within the brain. Results Optimal injection rates in males was 4−6 μl/min and 2−4 μl/min in females. The IA injection using these sex-specific rates resulted in appropriate limited dye delivery to only the ipsilateral region of the brain, without inducing a subarachnoid hemorrhage. Conclusion Upon adapting the IA administration model to rats, it was determined that the rate of infusion varied between males and females. This variability is an important consideration for studies utilizing both sexes, such as in ischemic stroke studies.
Evaporation and propagation of liquid drop streams at vacuum pressures: Experiments and modeling.

Evaporation of streams of liquid droplets in environments at vacuum pressures below the vapor pressure has not been widely studied. Here, experiments and simulations are reported that quantify the change in droplet diameter when a steady stream of \ensuremath{\approx}100 \ensuremath{\mu}m diameter drops is injected into a chamber initially evacuated to $l{10}^{--8}\phantom{\rule{0.16em}{0ex}}\mathrm{bar}$. In experiments, droplets fall through the center of a 0.8 m long liquid nitrogen cooled shroud, simulating infinity radiation and vapor mass flux boundary conditions. Experimentally measured changes in drop diameters vary from \ensuremath{\approx}0 to 6 \ensuremath{\mu}m when the initial vapor pressure is increased from ${10}^{--6}$ to ${10}^{--3}$ bar by heating the liquid. Measured diameter changes are predicted by a model based on the Hertz-Knudsen equation. One uncertainty in the calculation is the ``sticking coefficient'' \ensuremath{\beta}. Assuming a constant \ensuremath{\beta} for all conditions studied here, predicted diameter changes best match measurements with $\ensuremath{\beta}\ensuremath{\approx}0.3$. This value falls within the range of \ensuremath{\beta} reported in the literature for organic liquids. Finally, at the higher vapor pressure conditions considered here, the drop stream disperses transverse to the main flow direction. This spread is attributed to forces imparted by an absolute pressure gradient produced by the evaporating stream.
Non-Invasive Neutral Atom Density Measurements using fs-TALIF in a Magnetic Linear Plasma Device

We report on femtosecond TALIF measurements of neutral density in a mirror plasma device. We have measured H density down to 1011 cm-3, and the dynamics of the H neutrals in quasi-CW and pulsed plasma.
Invasions on Large and Small Scales: Management of a Well-established Crop Pest, the Colorado Potato Beetle

Understanding the movement of invading organisms is critical to predicting invasion dynamics. The Colorado potato beetle, Leptinotarsa decemlineata (Say), is an invasive species on multiple spatial and temporal scales, and can serve as a model for studies of invasion dynamics. It is the major insect defoliator of potato in North America, and successful management requires an understanding of CPB invasions of individual fields. Its origin, spread, and biology, especially the cycle of annual invasions of agricultural potato fields, are described. Approaches to reducing the size of colonizing populations include rotation, delay of planting, and treatments of field margins. Rotation and sub-lethal insecticide treatments can slow the establishment of invasions within fields. These approaches interact with a late season diapause switch away from reproduction to reduce the impact of CPB. The refuge approach to delaying the fixation of resistance alleles is designed to encourage alleles for susceptibility to invade treated areas. We present data from an experimental refuge crop planted adjacent to a field treated with imidacloprid, an insecticide for which there is high variation in resistance. The treated field was four times as resistant as the untreated side, and a cline in resistance was formed from the untreated to the treated portion of the field. The cline width of about 100 m provides an empirical basis for designing refuges to enhance the spread of alleles for susceptibility into treated areas and prevent fixation of resistance in the summer generation.
Theory and Educational Research : Toward Critical Social Explanation

Introduction: Critical Social Theory, Educational Research, and Intellectual Agency, Jean Anyon Part I - Theory and Explanatory Analysis 1. Critical Social Theory and the Study of Urban School Discipline: The Culture of Control in a Bronx High School, Kathleen Nolan Personal Reflection 2. Theorizing Student Poetry as Resistance to School-based Surveillance: Not Any Theory Will Do, Jen Weiss Personal Reflection 3. Theorizing Redistribution and Recognition in Urban Educational Research: 'How Do We Get Dictionaries at Cleveland?' Michael J. Dumas Personal Reflection Part II - Theorizing with Research Participants 4. Theorizing Back: An Approach to Participatory Policy Analysis, Eve Tuck Personal Reflection 5. Low-income Latina Parents, School Choice, and Pierre Bourdieu, Madeline Perez Personal Reflection 6. Queer Theory and Teen Sexuality: Unclear Lines, Darla Linville Personal Reflection Epilogue, Michelle Fine
Quantification of Uncertainty for Numerital Simulations with Confidence Intervals

We present a prediction and uncertainty assessment methodology for numerical simulation. The methodology allows prediction of confidence intervals. It has been developed jointly with a number of colleagues. It is a work in progress in the sense that not all components of the methodology are complete. The methodology, at its present level of deveopment,will be illustrated in two specific cases: the flow of oil in petroleum reservoirs (with prediction of production rates) and an analysis of solution errors for the simulation of shock wave interactions.The formalism assesses uncertainty and yields confidence intervals associated with its prediction. In the terminology of verification and validation, these predictions can be verified as exact within a framework for statistical inference, but they are not validated as being descriptive of a physical situation. In fact the present illustrative examples are simplified not intended to represent an experimental or engineering system.The methodology combines new developments in the traditional areas of oil reservoir upscaling and history matching with a new theory for numerical solution errors and with Bayesian inference. For the shock wave simulations, the new result is an error analysis for simple shock wave interactions.The significance of our methods, in the petroleum reservoir context, is their ability to predict the risk, or uncertainty associated with production rate forecasts, and not just the production rates themselves. The latter feature of this method, which is not standard, is useful for evaluation of decision alternatives. For shock wave interactions, the significance of the methodology will be to contribute to verification and validation of simulation codes.
Activation and safety analyses for the D-/sup 3/He fueled tokamak reactor Apollo

An activation analysis was performed for the Apollo D-/sup 3/He-fueled reactor. Three different steel alloys (PCA, 316 SS, and the manganese steel Tenelon) were considered for use in the first wall, shield, and vacuum vessel. The activity, decay heat, and biological hazard potential (BHP) following shutdown were compared for the three alloys. PCA and 316 SS yield similar results. The total integrated decay heat generated from the Tenelon over a period of one day after shutdown is about a factor of two larger than that generated from PCA and 316 SS. This is still more than an order of magnitude lower than that obtained in a D-T-fueled reactor. The results showed that after the full reactor lifetime, both PCA and Type 316 SS do not quality as class-C low-level waste (LLW), while Tenelon can be disposed of as class-C LLW. The thermal response of the shield following a loss-of-coolant accident (LOCA) was determined using the different structural materials. Using the magnet as a heat sink, it has been shown that the maximum first-wall temperature two weeks after LOCA levels off close to 200 degrees C even with Tenelon used as a structural material. The biological dose rate after shutdown at the back of the shield is excessive, implying that full remote maintenance is needed. However, the dose rate at the back of the magnet allows for limited access for magnet maintenance. >
Kinetics and mechanisms of the oxidation of myoglobin by Fe(III) and Cu(II) complexes.

Abstract Two distinct mechanisms by which sperm whale myoglobin reduces, respectively, complexes of Fe(III) and Cu(II) and, in turn, is oxidized to metmyoglobin have been characterized. For both mechanisms, deoxymyoglobin is the active reductant. An outer sphere electron transfer, probably at the edge of the heme, is involved for Fe(III)NTA (NTA is nitrilotriacetic acid. This pathway does not involve ionic binding of the Fe(III) complex to the protein. The most reactive species of Fe(III)NTA is uncharged. No inhibition is observed with Ni(II) or Zn(II). An outer sphere site specific electron transfer is operative for reduction of Cu(II) complexes. The site has been characterized using NMR spectroscopy and involves one or more histidines. There is an initial binding of the Cu(II) chelate. The ternary complex of chelator-Cu(II)-deoxymyoglobin is a mandatory intermediate. Ni(II) and Zn(II) compete with Cu(II) for the binding site. A scheme for the participation of either or both of these mechanisms in reduction reactions of heme proteins is proposed. Both the overall redox potential, ΔE 0 , and the stability constant for the ternary complex, K , govern the pathway and the reaction rate.
iii) Peripheral nerve repair

Abstract Peripheral nerve injuries affect all age groups and can be devastating to patients. A timely repair and thorough exam both preoperatively and intraoperatively can help increase the chances of a successful outcome. The technical aspects of peripheral nerve injury evaluation and repair must take into account the unique anatomy and function of the nervous system. Proper microsurgical techniques such as tension-free repair are a critical aspect of the repair process. Nerve grafts, conduits, and biotherapies are all viable ways to increase the odds of a meaningful repair. Proper immobilization, mobilization, and a targeted rehabilitation protocol are also important.
A closed-loop model of the canine cardiovascular system that includes ventricular interaction

A closed-loop model of cardiopulmonary circulation has been developed for the study of right-left ventricular interaction under physiologically normal and altered conditions. The core model provides insight into the effects of ventricular interaction and pericardial mechanics on hemodynamics. The complete model contains realistic descriptions of (a) the interacting ventricular free walls and septum, (b) the atria, (c) the pericardium, and (d) the systemic and pulmonary vascular loads. The current analysis extends previous work on ventricular interaction and pericardial influence under isolated heart conditions to loading conditions imposed by a closed-loop model of the circulation. A nonlinear least-squares parameter identification method (Levenberg-Marquardt algorithm) is used, together with parameter sensitivity analysis, to estimate the values of key parameters associated with the ventricular and circulation models. Pressure measurements taken at several anatomical locations in the circulation during open-chest experiments on dogs are used as data in the identification process. The complete circulatory model, including septal and pericardial coupling, serves as a virtual testbed for assessing the global affects of localized mechanical or hemodynamic alterations. Studies of both direct and series ventricular interaction, as well as the effect of the pericardium on cardiac performance, are accomplished with this model. Alterations in model parameter values are used to predict the impact of disease and/or clinical interventions on steady-state hemodynamic performance. Additionally, a software package titled CardioPV has been developed to integrate the complete model with data acquisition tools and a sophisticated graphical user interface. The complete software package enables users to collect experimental data, use the data to estimate model parameters, and view the model outputs in an online setting.
Comparison between Treatment Completers and Noncompleters among Dually Diagnosed Substance-Abusing Adolescents

Abstract The psychiatric and demographic characteristics that may distinguish treatment completers from noncompleters among hospitalized adolescents with substance abuse and comorbid psychiatric disorders were examined. Affective and adjustment disorders were more prevalent among treatment completers whereas noncompleters were more likely to be assigned a conduct disorder diagnosis. There were no differences between the groups with respect to demographic and legal status, education level and lifetime psychiatric diagnosis in the parents or caretakers, living arrangements, treatment history, and perception of treatment benefits. A higher percentage of treatment completers than noncompleters received psychotropic medications. The factors contributing to treatment termination as well as the clinical and research implications of the findings are discussed.
Halite and Hydrohalite from Lake Bonney, Taylor Valley, Antarctica

Halite (NaCl) and hydrohalite (NaCl·2H 2 O) have been found in the bottom sediments of Lake Bonney. These salts are in contact with the hypersaline bottom waters of the lake at depths below 28 m and occur with gypsum and calcite; a porous algal mat may be growing on at least a portion of the deposit. Hydrohalite formed during the coldest parts of the year is believed to be converted to halite during the slight warming during the austral summer. Thus, hydrohalite is only present on a year-to-year basis, whereas halite is preserved for long periods.
Cytoplasmic compartmentation of Gln3 during nitrogen catabolite repression and the mechanism of its nuclear localization during carbon starvation in Saccharomyces cerevisiae

Regulated intracellular localization of Gln3, the transcriptional activator responsible for nitrogen catabolite repression (NCR)-sensitive transcription, permits Saccharomyces cerevisiae to utilize good nitrogen sources (e.g. glutamine and ammonia) in preference to poor ones (e.g. proline). During nitrogen starvation or growth in medium containing a poor nitrogen source, Gln3 is nuclear and NCR-sensitive transcription is high. However, when cells are grown in excess nitrogen, Gln3 is localized to the cytoplasm with a concomitant decrease in gene expression. Treating cells with the Tor protein inhibitor, rapamycin, mimics nitrogen starvation. Recently, carbon starvation has been reported to cause nuclear localization of Gln3 and increased NCR-sensitive transcription. Here we show that nuclear localization of Gln3 during carbon starvation derives from its indirect effects on nitrogen metabolism, i.e. Gln3 does not move into the nucleus of carbon-starved cells if glutamine rather than ammonia is provided as the nitrogen source. In addition, these studies have clearly shown Gln3 is not uniformly distributed in the cytoplasm, but rather localizes to punctate or tubular structures. Analysis of these images by deconvolution microscopy suggests that Gln3 is concentrated in or associated with a highly structured system in the cytosol, one that is possibly vesicular in nature. This finding may impact significantly on how we view (i) the mechanism by which Tor regulates the intracellular localization of Gln3 and (ii) how proteins move into and out of the nucleus.
The hypnotic zolpidem increases the synchrony of BOLD signal fluctuations in widespread brain networks during a resting paradigm.

Abstract Networks of brain regions having synchronized fluctuations of the blood oxygen level-dependent functional magnetic resonance imaging (BOLD fMRI) time-series at rest, or “resting state networks” (RSNs), are emerging as a basis for understanding intrinsic brain activity. RSNs are topographically consistent with activity-related networks subserving sensory, motor, and cognitive processes, and studying their spontaneous fluctuations following acute drug challenge may provide a way to understand better the neuroanatomical substrates of drug action. The present within-subject double-blind study used BOLD fMRI at 3T to investigate the functional networks influenced by the non-benzodiazepine hypnotic zolpidem (Ambien®). Zolpidem is a positive modulator of γ-aminobutyric acid A (GABA A ) receptors, and engenders sedative effects that may be explained in part by how it modulates intrinsic brain activity. Healthy participants (n = 12) underwent fMRI scanning 45 min after acute oral administration of zolpidem (0, 5, 10, or 20 mg), and changes in BOLD signal were measured while participants gazed at a static fixation point (i.e., at rest). Data were analyzed using group independent component analysis (ICA) with dual regression and results indicated that compared to placebo, the highest dose of zolpidem increased functional connectivity within a number of sensory, motor, and limbic networks. These results are consistent with previous studies showing an increase in functional connectivity at rest following administration of the positive GABA A receptor modulators midazolam and alcohol, and suggest that investigating how zolpidem modulates intrinsic brain activity may have implications for understanding the etiology of its powerful sedative effects.
Role of the Advanced Practice Nurse in blood and marrow transplantation

The lecture will focus on the role of the Advanced Practice Nurse (Nurse Practitioner and Clinical Nurse Specialist), working in the field of blood and marrow transplantation at a comprehensive cancer center in the United States. Discussion will include components of the role, which are practitioner, educator, consultant, collaborator, and researcher. Identification of the differences in the inpatient and outpatient setting will be included. Advanced Practice Nurses (APN) contribution in examining issues related to quality of life and symptom management will be covered. Side effects of high-dose treatment, complications post-BMT, and acute graft vs. host disease will be included. Standards of care, established protocols and clinical guidelines will be shared to help identify scope of clinical practice for the APN. Multidisciplinary team approach will be stressed and a case study will exemplify this.
Recurrent aphthous stomatitis

Recurrent aphthous stomatitis remains a commonly occurring cause of oral pain and ulceration. Although the ulcerations of RAS are multifactorial and of unknown cause, recognition of the role of patient and environmental factors may be helpful in developing recommendations for treatment and prevention of future ulcers.
Microstructural development and solidification cracking susceptibility of Cu deposits on steel: Part I

The tool and die industry is interested in depositing Cu onto steel using direct metal deposition techniques in order to improve thermal management of mold dies manufactured from steel alloys. However, Cu is a known promoter of solidification cracking in steel. The goal of this work was to identify the range of Cu compositions in steel that cause cracking and understand the cracking susceptibility through analysis and modeling of microstructural development. A wide range of steel–Cu deposits, from approximately 3 to 97 wt% Cu, were fabricated using the gas tungsten arc welding (GTAW) process with cold wire feed. The deposits were found to be crack free when the concentration of Cu was below approximately 5 wt% or above approximately 52 wt%. Cracking was observed in deposits with Cu concentration between approximately 5 and 43 wt%. Thus, to ensure crack free deposition of Cu onto Steel, the concentration of the first layer must be about 52 wt% Cu or greater. The corresponding volume fraction of terminal Cu in samples that cracked was between approximately 0.1 and 27%. The resultant microstructures were characterized by various microscopy techniques to understand the influence of Cu on solidification cracking. Additionally, solidification modeling was undertaken to determine the amount of terminal Cu rich liquid that would form under equilibrium and non-equilibrium solidification conditions.
Who says what to whom: Why messengers and citizen beliefs matter in social policy framing

Abstract Issue frames (i.e., the thematic slants that elites use to structure issue debates) have been shown to alter how citizens think about social policy issues. However, support for a social policy issue not only depends on how the issue is framed, but also on the source or “messenger” associated with the frame. For the most part, issue frames have been faceless and research has failed to consider how characteristics of the frame's messenger such as expertise and trustworthiness influence citizens. The present study examines the influence that gun control frames and their messengers have on a variety of dependent variables. The results show that source cues moderate the impact of the frames, even when controlling for other variables. Specifically, credible sources significantly augment the effects of a frame while spokespersons with a perceived bias tend to weaken the frame's arguments and impact. These results point toward a more complex framing theory: public support for social issues depends on how the issue is framed, as well as who presents the message.
Generation of high-temperature and low-density plasmas for improved spectral resolutions in laser-induced breakdown spectroscopy

Improved spectral resolutions were achieved in laser-induced breakdown spectroscopy (LIBS) through generation of high-temperature and low-density plasmas. A first pulse from a KrF excimer laser was used to produce particles by perpendicularly irradiating targets in air. A second pulse from a 532 nm Nd:YAG laser was introduced parallel to the sample surface to reablate the particles. Optical scattering from the first-pulse plasmas was imaged to elucidate particle formation in the plasmas. Narrower line widths (full width at half maximums: FWHMs) and weaker self-absorption were observed from time-integrated LIBS spectra. Estimation of plasma temperatures and densities indicates that high temperature and low density can be achieved simultaneously in plasmas to improve LIBS resolutions.
INDUCED DIFFERENTIATION OF GERANIUM PLANTS FROM UNDIFFERENTIATED CALLUS IN VITRO

A B S T R A C T Geranium callus produced from explants of stem tip, internode pith with vascular tissute on synthetic media with or without coconut milk and 2,4-dichlorophenoxyacetic acid grew well for many generations, but only tracheids were induced in them. If callus produced on these media was subcultured immediately on Murashige and Skoog medium with 0.1 mg/liter/a-naphthalene acetic acid (NAA) and 10.0 mg/liter kinetin (K) and incubated at 16/8-hr light/dark cycle, shoots were induced in 8-10 weeks and roots in another 8-10 weeks. Callus produced on the MS medium with the same supplements of NAA and K, subcultured on the same medium and incubated in 16/8-hr light/dark cycle, produced shoots in 6-8 weeks. However, on callus subcultured more than three times, shoots differentiated with greater difficulty and none differentiated after six subeultures. Some abnormal shoot-like structures were also produced, the cells of which showed virus-like inclusion bodies. Requirements of the different varieties for differentiating organs differed. Among 12/12-, 1a/9-, 16/8-, and 20/4-hr light/dark photoperiods that induced differentiation, 15/9- and 16/8-hr were more effective than the others. Continuous illumination did not induce differentiation. Differentiated shoots formed roots more readily on a medium with reversed proportions of auxin and kinetin. On agar roots were devoid of root hairs. Root hairs were formed when the shoots and plantlets were cultured on filter-paper bridges. Many "mother" stock plants were produced. These are being studied for their growth qualities and for possible viruses and other pathogens.
A Fundamental Relationship Between Genotype Frequencies and Fitnesses

The set of possible postselection genotype frequencies in an infinite, randomly mating population is found. Geometric mean heterozygote frequency divided by geometric mean homozygote frequency equals two times the geometric mean heterozygote fitness divided by geometric mean homozygote fitness. The ratio of genotype frequencies provides a measure of genetic variation that is independent of allele frequencies. When this ratio does not equal two, either selection or population structure is present. Within-population HapMap data show population-specific patterns, while pooled data show an excess of homozygotes.
Motivations for movie attendance

This study investigated college students' motives for attendance at theatrically exhibited motion pictures and the relationship between the motivations and frequency of attendance, pattern of movie‐going, and the students' gender and age. Respondents (n = 493) completed a survey instrument consisting of 70 motivation items and other items. Factor analysis of the motivation items resulted in seven motives for movie attendance being identified. Results indicated that frequent movie‐goers reported greater identification with the movie motives than occasional or infrequent moviegoers; no marked differences in correlations between motives and frequency of attendance were found when age, gender, and attendance pattern were controlled.
CD4+V beta 8+ T cells mediate herpes stromal keratitis.

T lymphocytes are critical in mediating herpes simplex stromal keratitis (HSK). Using immunohistologic methods, we studied the T cell subsets and the T cell receptor variable region (TCR V beta) repertoire of T cells in the eye after corneal infection with HSV (KOS strain). We investigated the possibility that there might be differential V beta preferential usage in HSK resistant and susceptible BALB/c congenic mice that differ only in a small region associated with the Igh-1 gene locus. The inflamed corneas of HSK susceptible C.AL-20 mice were mainly infiltrated by CD4+ cells and by V beta 8 expressing cells. Such T cells were not seen in the corneas of resistant C.B-17 mice. Our results indicate that CD4+V beta 8+ cells are involved in mediating HSV-1 stromal keratitis.
CS Ed Week 2013: the hour of code

As advertised in the October 2013 edition of the Bulletin, this year's CS Ed Week encouraged everyone to host an "Hour of Code" event, in which educators hosted (at least) an hour of CS instruction to any audience they chose. SIGCSE members responded to the call enthusiastically. Here is just a sampling of the many great Hour of Code events that were put on.
Unilateral cystic, partially-differentiated nephroblastoma with bilateral nephroblastomatosis

An infant with a cystic, partially-differentiated nephroblastoma (CPDN) also had contralateral nephroblastomatosis, diagnosed on ultrasound and computerised tomography scans. Histology revealed bilateral nephroblastomatosis in addition to the right-sided CPDN. While CPDN is generally regarded as a tumour with a favourable prognosis, the association with bilateral nephroblastomatosis in this patient raised certain problems in management.
Optimization of subcutaneous vein contrast enhancement

A technique for enhancing the contrast of subcutaneous veins has been demonstrated. This techniques uses a near IR light source and one or more IR sensitive CCD TV cameras to produce a contrast enhanced image of the subcutaneous veins. This video image of the veins is projected back onto the patient's skin using a n LCD video projector. The use of an IR transmitting filter in front of the video cameras prevents any positive feedback from the visible light from the video projector from causing instabilities in the projected image. The demonstration contrast enhancing illuminator has been tested on adults and children, both Caucasian and African-American, and it enhances veins quite well in all cases. The most difficult cases are those where significant deposits of subcutaneous fat are present which make the veins invisible under normal room illumination. Recent attempts to see through fat using different IR wavelength bands and both linearly and circularly polarized light were unsuccessful. The key to seeing through fat turns out to be a very diffuse source of RI light. Results on adult and pediatric subjects are shown with this new IR light source.
Does body mass index affect outcomes of ambulatory knee and shoulder surgery

Purpose: Obesity is highly prevalent among patients with knee and shoulder injuries and is associated with greater odds of surgical treatment for these injuries. The purpose of this systematic review was to summarize the literature that has examined the association between body mass index (BMI) and outcomes of ambulatory knee and shoulder surgery. Methods: A literature search of PubMed and Medline was conducted up to December 2013. Studies that examined the association between BMI and outcomes after ambulatory knee and shoulder surgery (arthroscopy, repairs, and reconstructions) were included. Outcomes included postoperative functional scores, clinical scores, and complications. Results: Eighteen studies were included in this review; 13 involved knee surgery and 5 involved shoulder surgery. Seven knee studies and 2 shoulder studies found increased BMI to be associated with worse postoperative outcomes, whereas the remaining 9 studies did not find an association. Increased BMI was associated with worse clinical scores and less patient satisfaction after arthroscopic meniscectomy or debridement, and with worse clinical scores and lower activity levels after anterior cruciate ligament (ACL) reconstruction. It was also associated with worse clinical scores and a longer hospital stay after rotator cuff repair and with longer time to return to work after subacromial decompression. Six studies examined the association between BMI and complications, but all reported null findings. Conclusions: There is a lack of consensus in the literature regarding the association between BMI and ambulatory knee and shoulder surgery. Several factors may have contributed to contradictory findings, including variation in measuring and classifying anthropometry, postoperative outcomes, and follow-up time. Level of Evidence: Level IV, systematic review of Level I, III, and IV studies.
Density Functional Theory Study of Ligand Binding on CdSe (0001), (0001̄), and (112̄0) Single Crystal Relaxed and Reconstructed Surfaces: Implications for Nanocrystalline Growth

To gain a better understanding of the influence of ligand−surface interactions on nanocrystalline growth, periodic density functional theory calculations were employed in the study of the binding of organic ligands on the relaxed nonpolar (1120) and polar Se terminated (0001) surfaces and the relaxed and vacancy and adatom reconstructed Cd terminated (0001) surface. We examined chemisorption properties of phosphine, amine, phosphine oxide, carboxylic acid, and phosphinic acid model ligands, including preferred binding sites and geometries, vibrational frequencies, and binding energetics, and compared findings to intrinsic growth via addition of CdSe molecules or Cd and Se atoms. Our results indicate that binding of the ligands is preferred in the electron-poor 1-fold sites on all surfaces, with secondary coordination of the acidic ligands through the hydroxyl hydrogen to the electron-rich surface sites. In general ligand adsorption directly obstructs binding sites for growth species on the (1120) surfa...
FINITE ELEMENT MODELING OF MACHINING: FROM PROOF-OF-CONCEPT TO ENGINEERING APPLICATIONS

ABSTRACT For the past fifty years researchers have developed various machining models to improve cutting performance. Several approaches have been taken including analytical techniques, slipline field solutions, empirical approaches and finite element techniques. Of these, the finite element approach provides the most detailed information on chip formation and chip interaction with the cutting tool. Finite element models have been developed for calculating the stress, strain, strain-rate, and temperature distributions in both the chip and the workpiece. In addition, tool temperatures, machining forces and cutting power requirements can be determined. This information is extremely, useful for developing more fundamental understanding of complex machining problems. This paper presents a critique of finite element approaches used for simulating machining processes. Several applications of the finite element technique for simulating various machining problems are also reviewed. A new application for determini...
Properties of AlxGal-xAs/GaAs Multiple Quantum Well Laser Structures Grown By Molecular Beam Epitaxy

Multiple quantum well AI,Ga1-xAs/GaAs structures grown by molecular beam epitaxy were studied in order to determine the growth conditions that optimize luminescent response. Low temperature photolumines-cence results indicate that a growth temperature of 700°C is optimum. The quality of the interfaces between the AlxGa1-xAs and GaAs layers was assessed by means of modulation doped structures. It was found that the interfacial quality is optimized at a growth temperature of 700°C. Finally, room temperature continuous wave photopumped laser operation at a wavelength of A= 7270 A is demonstrated in these structures.
Motivations and benefits for attaining HR certifications

Purpose – The aim of this paper is to examine the motivations and benefits for pursuing or not pursuing the PHR and SPHR.Design/methodology/approach – Using a sample of 1,862 participants, the study used multinomial logistic and hierarchical linear regression to test six hypotheses.Findings – Participants pursuing SPHR were more likely to report intrinsic motivations pursuing certification, while PHR respondents were more likely to report extrinsic reasons. Other‐driven reasons were not significant predictors. Respondents not pursuing certification saw a lack of perceived benefits. Non‐pursuers of SPHR were concerned about time constraints. The pursuing and non‐pursuing groups did exhibit differences in their demographic and commitment profiles.Research limitations/implications – The sample is limited to only those professionals active in their local SHRM chapters. The data were cross‐sectional. Future research needs to address the validity of Human Resource Certification Institute (HRCI) certification an...