cssi/SciSciGPT-SciSciNet huggingface dataset:
Enzyme-linked immunoelectrotransfer blot analysis of excretory-secretory proteins of Fascioloides magna and Fasciola hepatica

Fasciola hepatica is a parasite of cattle (Bos taurus), but not of white-tailed deer (Odocoileus virginianus), while Fascioloides magna is a parasite of white-tailed deer which also infects cattle as dead-end host. Adult parasites were collected from naturally infected white-tailed deer or cattle. Excretory-secretory proteins (ESP) were obtained from each parasite. Protein banding patterns were analysed on sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and probed using sera from experimentally infected deer of cattle using enzyme-linked immunoelectrotransfer blot (EITB, also known as Western blot) analysis. Protein banding patterns of the two species were different. EITB analysis of Fascioloides magna ESP using sera from Fascioloides magna infected deer or cattle identified three bands of approximately 17, 22 and 27 kDa of which the 27 kDa antigen cross-reacted with sera from Fasciola hepatica infected cattle. EITB analysis of Fasciola hepatica ESP probed with sera from Fasciola hepatica infected cattle identified three bands of approximately 15, 26 and 46 kDa. The 46 and 26 kDa ESP cross-reacted with sera from Fascioloides magna infected cattle, but not with sera from Fascioloides magna infected deer. The band at 15 kDa which reacted specifically for Fasciola hepatica infected cattle sera consisted of two protein bands close to each other as seen on the SDS-PAGE gel. The EITB reaction at approximately 17 kDa and 22 kDa of Fascioloides magna ESP, and at approximately 15 kDa of Fasciola hepatica ESP can be used for species specific diagnosis.
A simplified process flow for silicon heterojunction interdigitated back contact solar cells: Using shadow masks and tunnel junctions

A novel process flow, which can allow the formation of interdigitated p- and n-type a-Si strips and corresponding transparent conductive oxide (TCO) and metal layers for silicon heterojunction interdigitated back contact (SHJ-IBC) solar cells using only a single alignment step and without using any resist patterning is presented. The flow is based on the deposition of a-Si, TCO and metal layers through a stack of shadow masks. Three variation of the flow are described. Several key process components to include a-Si deposition and H 2 plasma etch through the shadow mask are demonstrated and described.
Procedures Performed by Hospitalist and Non-hospitalist General Internists

BACKGROUND In caring exclusively for inpatients, hospitalists are expected to perform hospital procedures. The type and frequency of procedures they perform are not well characterized.
Enantiospecific synthesis of (+)-alstonisine via a stereospecific osmylation process.

The first enantiospecific total synthesis of (+)-alstonisine has been accomplished from d-tryptophan methyl ester 13 in 12% overall yield (in 17 reaction vessels). A diastereospecific osmylation process has been employed as a key step to convert indole 18 into spirocyclic oxindole 19. Mechanistic studies of the stereoselective osmylation of the 2,3-indole double bond of indole alkaloids has been carried out. Compelling evidence for the intramolecular delivery of OsO4 via Nb-complexation was obtained for the osmylation process. The correct structure of (+)-alstonisine (1) was determined by NOE spectroscopic experiments and further confirmed by single-crystal X-ray analysis.
Intelligent I/O rule-based input/output processing for operating systems

IntelligentI/O is a rule based general model for performing "intelligent" processing of Input/Output operations in an Operating System. In a new interface layer between the applications and the kernel I/O functions, rules determine actions to be performed at I/O time which in turn invoke programs in user space. IntelligentI/O permits complete implementation in user space applications that would normally require ad-hoc kernel modifications such as a Network File System. It also serves to implement features that would normally have to be embedded in an application, such as Automatic Format Conversion or Revision Tracking. We later present SuperFile, a simple yet powerful existing implementation of the IntelligentI/O model, together with a number of applications developed using SuperFile.
Cardiovascular effects of cholinergic agents in the ventral-lateral midbrain periaqueductal gray of the rat.

Abstract Local injection of the cholinergic agonist carbachol (1–5 nmol) into the ventral lateral periaqueductal gray region of the midbrain produced a dose-dependent bradycardia with minimal effects on blood pressure in the urethane-anesthetized rat. The decrease in heart rate was maximal in the region of the nuclei of the third and fourth cranial nerves. Intravenous injection of carbachol (5 nmol) had little effect on the heart rate. Injection of (−)-nicotine (5 nmol) into this region of the brain produced a slight, but significant, increase in heart rate. Pretreatment with an intracranial injection of atropine greatly reduced the bradycardia response, whereas local injection of mecamylamine or hexamethonium had no effect. The bradycardia resulting from cholinergic stimulation in this area of the brain appears to result from an enhanced vagal influence on the heart, as pretreatment with intravenous atropine methyl nitrate (1 mg kg ) prevented the carbachol-induced bradycardia. The possible physiological significance of this response is discussed.
The Henley Staple-Suture Technique for Laparoscopic Burch Colposuspension

A simplified approach to laparoscopic retropubic colposuspension uses staples and suture. This technique dramatically reduces the risk of injury to the bladder, and makes proper fixation of the urethra precise and rapid.
Polynomials which take Gaussian integer values at Gaussian integers

Abstract A factorial set for the Gaussian integers is a set G = {g1, g2 … gn} of Gaussian integers such that G(z) = Π k (z − g k ) g k takes Gaussian integer values at Gaussian integers. We characterize factorial sets and give a lower bound for max ∥z∥2= n π ∥ G(z)∥ . It is conjectured that there are infinitely many factorial sets. A Gaussian integer valued polynomial (GIP) is a polynomial with the title property. A bound similar to the above is given for max∥z∥2=n ∥ G(z)∥ if G(z) is a GIP. There is a relation between factorial sets and testing for GIP's. We discuss this and close with some examples of factorial sets, and speculate on how to find more.
Managing suicidality in home-based telehealth

We describe the case of a US veteran from the war in Afghanistan with post-traumatic stress disorder (PTSD). The patient was undergoing treatment at home via telehealth as part of a research trial. In week six, he presented with severe suicidal ideation and required emergency hospitalization. Through a series of immediate enhanced communications (i.e. by videoconference) between the patient, patient's family, treatment team and local resources, the patient's symptoms were assessed to identify suicidality and an intervention was successfully carried out, involving the development of a safety plan and eventual transportation to an inpatient unit at the local Veterans Administration Medical Center, where he was hospitalized for three days. This demonstrates the value of telehealth in identifying and treating severe psychiatric symptoms in addition to supporting the safety of these procedures to address suicidality.
Reduced Selenium-Binding Protein 1 in Breast Cancer Correlates with Poor Survival and Resistance to the Anti-Proliferative Effects of Selenium

Supplemental dietary selenium is associated with reduced incidence of many cancers. The antitumor function of selenium is thought to be mediated through selenium-binding protein 1 (SELENBP1). However, the significance of SELENBP1 expression in breast cancer is still largely unknown. A total of 95 normal and tumor tissues assay and 12 breast cancer cell lines were used in this study. We found that SELENBP1 expression in breast cancer tissues is reduced compared to normal control. Low SELENBP1 expression in ER+ breast cancer patients was significantly associated with poor survival (p<0.01), and SELENBP1 levels progressively decreased with advancing clinical stages of breast cancer. 17-β estradiol (E2) treatment of high SELENBP1-expressing ER+ cell lines led to a down-regulation of SELENBP1, a result that did not occur in ER– cell lines. However, after ectopic expression of ER in an originally ER– cell line, down-regulation of SELENBP1 upon E2 treatment was observed. In addition, selenium treatment resulted in reduced cell proliferation in endogenous SELENBP1 high cells; however, after knocking-down SELENBP1, we observed no significant reduction in cell proliferation. Similarly, selenium has no effect on inhibition of cell proliferation in low endogenous SELENBP1 cells, but the inhibitory effect is regained following ectopic SELENBP1 expression. Furthermore, E2 treatment of an ER silenced high endogenous SELENBP1 expressing cell line showed no abolishment of cell proliferation inhibition upon selenium treatment. These data indicate that SELENBP1 expression is regulated via estrogen and that the cell proliferation inhibition effect of selenium treatment is dependent on the high level of SELENBP1 expression. Therefore, the expression level of SELENBP1 could be an important marker for predicting survival and effectiveness of selenium supplementation in breast cancer. This is the first study to reveal the importance of monitoring SELENBP1 expression as a potential biomarker in contributing to breast cancer prevention and treatment.
Nanoscale assembly into extended and continuous structures and hybrid materials

Harnessing synthetic power to create novel materials with unique assembly properties is of fundamental interest for pushing the limits of molecular and macromolecular assembly, while further holding the potential for improving electronic and medical device performance. Controlling the assembly of aromatic molecules into nanostructures provides routes towards continuous and extended structures with performance that is improved markedly over that of their individual molecular components, opening possibilities for the formation of composites that have tailored interactions with other materials and thus improved applications. This review covers recent advances in the synthesis of conjugated materials, their controlled assembly into nanoscale architectures and implementation into devices. Specifically, we discuss the solution-based assembly of polythiophene into nanowire fibrils, the formation of columnar stacks of hexabenzocoronene liquid crystals and the preparation of functionalized solution processible graphene for nanocomposite formation. When polymers are mentioned, it is ‘plastics’ that typically spring to mind. Yet the assembly of conjugated polymers or aromatic molecules into hierarchical and hybrid structures also brings about materials that are attractive for electronic and medical devices. Emily Pentzer and Todd Emrick from the University of Massachusetts review recent advances into the preparation of well-defined molecular building blocks, their assembly into complex architectures, and the properties emerging from these arrangements. This approach is illustrated by the variety of assemblies featuring conjugated polythiophene chains, such as nanowires, fibrils that can further aggregate into ribbons, or composites with quantum dots. These higher-order structures display a variety of electronic properties, useful in semiconductor and photovoltaic applications among others. Another example of the potential of this approach is the construction of carbon nanotubes or graphene flakes from aromatic molecules. Pentzer and Emrick also highlight the remaining challenges that relate to controlling the structures obtained, their stability, and their integration into devices. Poly(3-hexylthiophene) nanowires, microns in length and nanometers in diameter, are stably suspended in solution, and crystallize by adjusting solvent strength. Cocrystalization of P3HT with P3HT-covered CdSe nanorods gave hybrid nanostructures in which the p-type P3HT fibrils were flanked by the n-type CdSe nanorods. The close proximity and arrangement of the two materials provides direct, continuous pathways suitable for charge transport in photovoltaic devices.
Rat cellular retinol-binding protein: cDNA sequence and rapid retinol-dependent accumulation of mRNA

Cellular retinol-binding protein (CRBP) may be an important mediator of vitamin A action. We report here the identification of a cDNA clone corresponding to the rat CRBP gene. The cDNA is 695 nucleotides long, with an open reading frame corresponding to a protein of 134 amino acids. The deduced amino acid sequence is identical with that of rat CRBP. The nucleotide sequence shows 90.5% similarity with the human CRBP cDNA sequence. Genomic DNA analysis indicates that CRBP is present in one, or at most two, copies within the rat genome. Analysis of mRNA reveals a single species in every tissue tested and suggests that the isolated cDNA is full-length. Finally, when retinol-deficient rats are fed retinyl acetate for 4 hr, about 4-fold accumulation of CRBP-specific mRNA is observed in the lungs. This rapid effect suggests that the micronutrient retinol may directly influence the expression of its specific intracellular binding protein.
Response of a sonar array to turbulent boundary layer noise on a cylinder

Abstract The response of an array of finite transducers, flush-mounted on the surface of a rigid cylinder, to flow noise induced by a low Mach number statistically stationary turbulent boundary layer on the surface is examined. It is found that for an array of uniformly responding transducers of dimensions and array spacing of O (l) to a frequency ω = O (c/l) (c being the sound speed), the response is such that the ratio of the contribution to the response from the high, convective, wavenumber elements of the power spectrum to that from the low, sonic, wavenumber elements is O (M-1 sin o/log ((ωa/c) sin o)) away from endfire (o = 0 or π) and O((MN1 log (ωa/c N 1 ))-1(ωa/c)) in the vicinity of endfire; here M is the Mach number, a is the radius of the cylinder and N1 is the number of axial elements of the array, and the number of transverse elements is taken to be O(1). It is believed that a choice of transducers the sensitivity of which is tapered at the edge would considerably reduce this ratio. The sonic wavenumber contribution to the power spectrum of the array response varies as (ωdx/c)-1 log (ωa/c) for a broadside beam angle and as (ωa/c)-1 log (ωa/c) in the vicinity of endfire, where dx is the array spacing. Assuming that the high wavenumber contribution can be suitably suppressed, it is shown that for a given frequency and a given angle of steer and with transducer dimensions and array spacing of O (c/ω), the ratio of the power spectrum of the response of an array to that of the response of a single transducer decreases with increase in the radius of the cylinder.
An analgesic mixture for minor surgical procedures in young children.

Summary A mixture of meperidine hydrochloride(Demerol), chlorpromazine hydrochloride (Thorazine), and promethazine hydrochloride (Phenergan) has been used in a total of eighty-nine cardiac catheterizations and angiocardiographic studies. This type of sedation has practically replaced all forms of general anesthesia formerly used during such procedures at the University of Virginia. This mixture has proved safe to use, easy to administer, effective in sedating the patient, and has appreciably reduced the number of postoperative complications and need for nursing care.
Assessment, Objectivity, and Interaction: The Case of Patient Compliance with Medical Treatment Regimens.

Much of the daily work of professional organizations is accomplished via interaction between representatives of those institutions and laypeople. Scholars of talk in institutional settings have argued that lay-professional interaction is often assumed mistakenly to operate as a neutral conduit for professionals to gain information relevant to their work. I use the case of doctor-patient interaction to examine how patient compliance with diabetes treatment is assessed in interaction. Despite the abundance of research on patient compliance, the approaches to this work show a conceptual uniformity stemming from the notion that noncompliance is a matter of individually based, essential behaviors. Using conversation analysis, I draw attention to the ways in which compliance is produced jointly in and through institutional talk. As a result, I seek to elaborate two extant literatures: interdisciplinary research on patient compliance as an aspect of health behavior, and social psychological literature on attitud...
Design and implementation of a Fast Poisson solver for microcomputers

In this note we describe the design and implementation of a Fast Poisson solver for microcomputers [1]. A Double Fourier Transformation Algorithm [4] was used with Sinusoidal Transformations [2] for the different boundary conditions. Table 1 summarizes the classification of Sinusoidal Transformations according to different boundary conditions.
The reproductive biology of the dab Limanda limanda (L.) in the North Sea: Seasonal changes in the ovary

Oogenesis in the dab is described in six easily identifiable stages: oogonium (Stage I), primary oocyte (II), primary vitellogenesis (III), secondary vitellogenesis (IV), tertiary vitellogenesis (V) and hyaline oocyte (VI). The annual reproductive cycle in female dab may be divided into four morphologically and histologically distinct periods: prespawning (October–January), spawning (February–April), postspawning (May–June) and resting (July–September) period.
The determination of carrier mobilities in CIGS photovoltaic devices using high-frequency admittance measurements

We apply a new method to deduce the hole carrier mobilities of Cu(InGa)Se2 (CIGS) polycrystalline films that have been incorporated into working solar cell devices. Our approach extends admittance measurements to frequencies of nearly 100 MHz in order to observe the characteristic dielectric carrier freeze-out and thus deduce the resistivity of the undepleted bulk absorber region in these devices. This resistivity, together with carrier densities deduced using drive-level capacitance profiling have allowed us to obtain the hole mobilities in the temperature regime 125 to 200 K. Values in the range 3–22 cm2 V−1 s−1 are obtained. In addition, we have examined the changes in mobility that occur as a result of light-soaking these devices, after which the carrier density is roughly doubled. Implications of these results toward understanding carrier mobility in CIGS polycrystalline films are discussed.
History of cardiac radiology.

T he last century has witnessed extraordinary advances in the capacity to display the heart borders and its interior anatomy in living subjects I 1 1. Fluoroscopy and radiography were first used and described in I 896, within months of Roentgen’s discovery of X-rays. In the early part of the 20th century, plain film findings for heart disease began to be characterized and recorded in the literature. Although angiocardiography was based on developments in the 1920s and before, its introduction in clinical subjects awaited the 1930s, and its evolution to modern form took place in the I 940s and 1950s, together with aortography. The feasibility ofeoronary arteriography was demonstrated and its use spread during the 1960s. Echocardiography, isotope studies of the heart, CT, and MR imaging are later developments not covered in this account, which focuses primarily on conventional radiology and angiocardiography.
Solubilization of bound lactate dehydrogenase by NADH in homogenates of trout skeletal muscle as a function of tissue concentration.

Abstract Solubilization of lactate dehydrogenase (LDH) bound to homogenized muscle tissue is accomplished by NADH, and to a lesser extent by NAD+, at concentrations in the range used in assays and found in tissues. This solubilization increases with decreasing concentration of tissue in the homogenate. Under normal conditions of assay, one would expect LDH to be in a soluble form. At high tissue concentrations, which are probably more like conditions in situ , a considerable part of the LDH remains bound. Binding could affect the kinetics or equilibrium of the reaction.
Simple calculation of the critical mass for highly enriched uranium and plutonium-239

The correct calculation of and values for the critical mass of uranium or plutonium necessary for a nuclear fission weapon have long been understood and publicly available. The calculation requires solving the radial component in spherical coordinates of a diffusion equation with a source term, so is beyond the reach of most public policy and many first-year college physics students. Yet it is important for the basic physical ideas behind the calculation to be understood by those without calculus who are nonetheless interested in international security, arms control, or nuclear non-proliferation. This article estimates the critical mass in an intuitive way that requires only algebra.
Consequences of the resistance to drug-induced topoisomerase II-mediated DNA cleavage

A rapid and accurate quantitative clinical assay that could predict the likelihood of response of an individual patient's cancer to chemotherapy would be invaluable. The assay's identification of active agents would ensure the patient of the greatest benefit from therapy. Identification of inactive agents would spare the patient unnecessary toxic effects of the drugs. Development of such an assay necessitates the identification of drug targets, the ability to measure the drug-target interaction in clinical samples, and the knowledge that measurement of the drug-target interaction is associated with the mechanism by which the drug kills malignant cells. Focusing on drugs that target topoisomerases, my laboratory has begun to develop such an assay based upon studies in human leukemia cell lines exhibiting different sensitivities to topoisomerase-reactive drugs. The focus of this paper is the basic research that supports the clinical approach we are taking.
Proposal for a semiconductor high resolution tracking detector

Abstract A “new” concept for detection and tracking of charged particles in high energy physics experiments is proposed. It combines a well known high purity semiconductor diode detector (HPSDD) with a heterojunction structure (HJ) and a negative electron affinity (NEA) surface. The detector should be capable of providing a two dimensional view (few cm2) of multi-track events with the following properties: a) position resolution down to a few μm (108 position elements); b) high density of information (102−103 dots per mm of minimum ionizing track); c) high rate capabilities (few MHz); d) live operation with options to be triggered and/or the information from the detector can be used as an input for the decision to record an event.
Effect of Stuffing Variables on the Quality of Chicken Frankfurters

Abstract INTRODUCTION SEVERAL attempts have been made in this laboratory to improve the texture of frankfurters made from chicken by increasing their firmness. Increasing the level of skin has been found to increase firmness (Baker et al., 1968) but the chewiness of the skin particles was considered objectionable by some people. Baker et al. (1969) also reported that firmness of frankfurters was affected by protein and fat content. However, these factors affect the chemical composition of the product and this paper will investigate some of the other factors which may influence firmness. It was stated (American Meat Institute, 1960) that there appears to be no difference between the chemical composition of frankfurters processed in natural casings and those processed in cellulosic casings, when the same emulsion is used for each. Regardless, many people feel that frankfurters made in natural casings are a superior product. There are also now available regenerated collagen…
Effect of redox state on unfolding energetics of heme proteins.

Both the enthalpic and entropic contributions to unfolding of three heme proteins, cytochrome b562, cytochrome c and myoglobin, are larger for the reduced than for the oxidized form. Thus, the higher thermodynamic stability of a reduced, as compared to an oxidized, heme protein is the net result of a large increase of favorable enthalpy and a small increase in unfavorable entropy. Upon comparing the unfolding energetics of the heme proteins to those of other single-domain proteins I find that protein length is the primary determinant of the thermodynamics.
On the erergy and configuration of orthogonal misfit dislocations

Abstract The local interactions and reactions or orthogonal misfit dislocations at {001} interfaces in cubic crystals are analyzed. The relaxations are shown to have small influences on the energies of dislocation arrays but are important in retarding the motion of spreading dislocation loops.
Molluscan Cells: Dissociation and Reaggregation

Dissociation of the ovotestes of Helix pomatia requires the presence of carbohydrates as well as trypsin, but is independent of cation content. Dispersed cells obtained from the ovotestes reaggregate rapidly into histotypically organized tissue. The role of cellular adhesiveness is facilitated by centrifugation, but pseudopodial activity of the cells is suggested as another factor in reaggregation.
TOXICITY OF CERTAIN WIDELY USED ANTISEPTICS

1. The substances injected intraperitoneally into mice and guinea pigs arranged in the order of their decreasing toxicity are: eucalyptol and brilliant green; mercurophen; mercuric chloride and chloramine-T; dichloramine-T and proflavine; hychlorite, Dakin's hypochlorite, Javelle water, and magnesium hypochlorite; iodine and phenol. 2. Now that Dakin's bland solvent, chlorcosane, is available as a vehicle for dichloramine-T, eucalyptol should probably be discarded for this purpose because of its much greater toxicity. 3. Inasmuch as experienced surgeons do not approve of the injection of solutions of iodine and phenol into closed cavities, it would seem advisable not to use any of the antiseptics here discussed in this manner inasmuch as all exhibit a greater toxicity for mice and guinea pigs than the two chemicals first named. 4. The method of testing toxicity of antiseptics by subcutaneous injection is not satisfactory because exudation and subsequent sloughing reduce the rate of absorption and make uncertain the amount finally absorbed.
Homopolymerization and copolymerization of phenyltrichlorosilane by sonochemical reductive coupling in the presence of sodium

Soluble polymers have been prepared by the sonochemical reductive coupling of phenyltrichlorosilane in toluene in the presence of sodium. Copolymers of phenyltrichlorosilane with phenylmethyldi-chlorosilane were synthesized. The obtained products are of relatively low molecular weight (¯Mn<10,000). Investigations by 29 Si NMR, UV and by the kinetic studies of the iodine addition indicate that polymers consist of fused cyclopolysilanes with 40% content of strained rings (probably four-membered). Homopolymerization and copolymerization of n-hexyl-trichlorosilane and methyltrichlorosilane is compared with that of phenyltrichlorosilane. The former monomer yields soluble homopolymer and copolymers of relatively higher molecular weights than phenyltrichlorosilane. Methyltrichlorosilane yields usually insoluble products and only at a concentration below 20%, were soluble copolymers formed.
Shaping the future of IT within the academy

We summarize the problems and potential solutions put forward in the four articles by the Deans and then offer three lenses to consider as we reimagine the future of IT education and research. These lenses include major disruptions in education that are already emerging, the need to harness the huge, ever, payoff from the rapid, but predictable, growth in information technology, and, what seems likely to be, a painful transition from an economy based largely on labor and material goods to one based on software and information goods.
SEARCHES FOR SINGLE-TOP-QUARK PRODUCTION WITH THE CDF DETECTOR AT FERMILAB

In the proton–antiproton collisions at Fermilab, individual top quarks are expected to be produced by an electroweak mechanism referred to as single-top-quark production. In this paper we review the CDF results of the search for single-top-quarks, along with the prospects for the current collider run.
The Clinical Diagnosis and Surgical Management of Ruptured Mitral Chordae Tendineae

Six patients with mitral insufficiency secondary to ruptured chordae tendineae are presented. Each patient underwent surgical correction of the deformed valve. In two instances the posterior leaflet was involved while in four the anterior leaflet was affected. Three patients had definite bacterial endocarditis that appeared to be related to the onset of cardiac symptoms. In the two instances of posterior valve involvement there were an aortic thrill and a harsh systolic murmur, whereas in two of the four with rupture of the anterior leaflet an aortic systolic murmur was heard but no thrill was felt. The other two with anterior leaflet disease disclosed no murmurs in the aortic area. These findings are considered to be a result of the direction of the regurgitant jet and the area in which they strike the left atrium. None of the patients had hemodynamic evidence of aortic valve disease and in each instance the aortic systolic murmur decreased or disappeared after surgery. Each patient had gross left atrial...
Decomposing finitely generated integral monoids by elimination

Abstract A finitely generated integral monoid can always be decomposed into a finite (although generally exponential) number of integral monoids having special structure, in that their related integer programming feasibility problems can be solved in polynomial time. The decomposition can be constructed using an elimination scheme due to Presburger and Williams that generalizes Fourier-Motzkin elimination.
Managing Unstructured Data With Structured Legacy Systems

In this paper we describe an approach and system for managing and joining enterprise semi-structured data in a high-throughput, nimble, and scalable systems with traditional relational database management systems (RDBMS). This paper presents the second release of NASA's NETMARK system. NETMARK is an Enterprise Information Integration (EII) framework based on a modern "schema-less" concept approach. NETMARK "schema- less" information integration reinvents the way of managing semi-structured documents within traditional RDBMS. We describe in particular detail the unique underlying data storage approach and efficient query processing mechanisms given the new proposed storage system upgrade. We present an extensive evaluation of the virtual union between NETMARK with the persistent schemas similar to commercial off-the-self products, such as Systems Applications and Products (SAP), currently utilized for NASA's Financial System, through well validated applications. At the heart of the approach is the philosophy of a well-defined and focused approach on most common data management requirements in the enterprise, and not burdening users and application developers with unnecessary complexity and formal data integration processes. This paper presents the details of achieving the integration between two incompatible systems.
Paralleling rotor and stator

A wound rotor induction machine may be given special characteristics by connecting the stator and rotor windings in parallel, either directly or through an auto-transformer. Pull-out torque, hp. output, and efficiency at large loads are increased for motor operation; and maximum kva. output is increased for operation as an induction generator.
Determination of neuraminic acid in cerebral tissues

Abstract The concentration of neuraminic acid was determined in the gray matter of the insular and temporal cortex as well as of the basal ganglia, and in the white matter of normal autopsy human brains. Samples from the cerebral tissues were separated into two fractions: a water-soluble lipid and a lipid-free residue. Neuraminic acid was determined in both fractions with the orcinol test after elimination of interfering substances by column chromatography. Only tissues from non-neurological cases were analyzed in this study in order to obtain control values for comparison with samples from areas with neurological disorders involving neuraminic acid.
Spectral distribution of drift-wave fluctuations in tokamaks

An expression for the spectral distribution of drift-wave fluctuations is obtained from a new mode-coupling equation that describes the superposition of drift-wave normal modes induced by the divergence of the nonlinear $\stackrel{\ensuremath{\rightarrow}}{E}\ifmmode\times\else\texttimes\fi{}\stackrel{\ensuremath{\rightarrow}}{B}$ convective flux. Computations for the adiabatic toroidal compressor experiment indicate that the observed spectrum is consistent with the theoretical spectrum.
Dehydropeptidase I activities in human intracranial neoplasms

Abstract Dehydropeptidase I activities have been measured in samples of human cerebral cortex, subcortical white matter, cortical gliosis, and a variety of intracranial neoplasms. Particular attention has been directed toward activities of the enzyme in relation to degree of malignancy and toward relative levels in neurons as compared to neuroglia cells. A microspectrophotometric method has been used with glycyldehydroalanine as substrate. The enzyme activity was found in about equal quantities in cortex and white matter. No correlation could be made with the malignant process. On the other hand, enhanced activity was observed in the presence of large numbers of neuroglia cells, whether astrocytes or oligodendrocytes.
Multi-query interactive image and video retrieval -: theory and practice

We propose a new interactive image and video retrieval system called multi-query interactive retrieval, which is designed to jointly optimize the retrieval performance on multiple query topics. The proposed system employs a learning-based hybrid retrieval approach, which can automatically switch between tagging and browsing interface based on user labeling efficiency. To formalize the retrieval process, we use two formal annotation models to track and estimate the retrieval time for each method. Based on the parameters of these models, the system integrates the tagging-based and browsing-based methods in order to minimize overall retrieval time across the full set of query topics. This hybrid multi-topic retrieval approach is demonstrated to be highly effective on two large-scale video collections.
The Extreme Ultraviolet Explorer: Optics Fabrication And Performance

The fabrication methods, testing and evaluation techniques, and performance results are presented for the mirrors for the Extreme Ultraviolet Explorer (EUVE). The finest mirror produced to date has a measured half energy width of 8 arcsec at optical wavelengths. With a polished nickel surface, the telescope throughput was 35 percent at 44 A and 60 percent at 256 A. The surface roughness is 20 A rms.
Male external genitalia and systematic relationships of the Japanese macaque ( Macaca fuscata Blyth, 1875)

Penial morphology was studied in six preserved specimens of the Japanese macaque,Macaca fuscata. Structure of the glans penis and baculum inM. fuscata is essentially similar to that in the rhesus macaque,M. mulatta. With age the skin of the penis inM. fuscata apparently becomes progressively more darkly and extensively pigmented, and the baculum becomes progressively longer. One immature specimen examined, with penial skin unpigmented and baculum cartilaginous, appears to be abnormally retarded in penial development. Penial morphology suggests that the allopatric speciesM. fuscata, M. mulatta, M. cyclopis, andM. fascicularis constitute a closely interrelated group. Contrary to a previous report, there is no evidence that penial morphology inM. fuscata is transitional to that inM. radiata andM. sinica. InM. fuscata, M. mulatta, andM. fascicularis, latitudinal variation of body size and relative tail length conforms toBergmann's rule andAllen's rule; external proportions in three specimens ofM. cyclopis only partly conform to this pattern.
Whole genome transcript profiling from fingerstick blood samples: a comparison and feasibility study

Whole genome gene expression profiling has revolutionized research in the past decade especially with the advent of microarrays. Recently, there have been significant improvements in whole blood RNA isolation techniques which, through stabilization of RNA at the time of sample collection, avoid bias and artifacts introduced during sample handling. Despite these improvements, current human whole blood RNA stabilization/isolation kits are limited by the requirement of a venous blood sample of at least 2.5 mL. While fingerstick blood collection has been used for many different assays, there has yet to be a kit developed to isolate high quality RNA for use in gene expression studies from such small human samples. The clinical and field testing advantages of obtaining reliable and reproducible gene expression data from a fingerstick are many; it is less invasive, time saving, more mobile, and eliminates the need of a trained phlebotomist. Furthermore, this method could also be employed in small animal studies, i.e. mice, where larger sample collections often require sacrificing the animal. In this study, we offer a rapid and simple method to extract sufficient amounts of high quality total RNA from approximately 70 μl of whole blood collected via a fingerstick using a modified protocol of the commercially available Qiagen PAXgene RNA Blood Kit. From two sets of fingerstick collections, about 70 uL whole blood collected via finger lancet and capillary tube, we recovered an average of 252.6 ng total RNA with an average RIN of 9.3. The post-amplification yields for 50 ng of total RNA averaged at 7.0 ug cDNA. The cDNA hybridized to Affymetrix HG-U133 Plus 2.0 GeneChips had an average % Present call of 52.5%. Both fingerstick collections were highly correlated with r2 values ranging from 0.94 to 0.97. Similarly both fingerstick collections were highly correlated to the venous collection with r2 values ranging from 0.88 to 0.96 for fingerstick collection 1 and 0.94 to 0.96 for fingerstick collection 2. Our comparisons of RNA quality and gene expression data of the fingerstick method with traditionally processed sample workflows demonstrate excellent RNA quality from the capillary collection as well as very high correlations of gene expression data.
Living Donor Kidney Transplantation: Facilitating Education about Live Kidney Donation--Recommendations from a Consensus Conference

The Best Practice in Live Kidney Donation Consensus Conference held in June of 2014 included the Best Practices in Living Donor Education Workgroup, whose charge was to identify best practice strategies in education of living donors, community outreach initiatives, commercial media, solicitation, and state registries. The workgroup’s goal was to identify critical content to include in living kidney donor education and best methods to deliver educational content. A detailed summary of considerations regarding educational content issues for potential living kidney donors is presented, including the consensus that was reached. Educational topics that may require updating on the basis of emerging studies on living kidney donor health outcomes are also presented. Enhancing the educational process is important for increasing living donor comprehension to optimize informed decision-making.
How soon can a patient undergo noncardiac surgery after receiving a drug-eluting stent?

Lacking direct data, we base our approach on data from patients with bare-metal stents and from patients receiving antiplatelet therapy for acute coronary syndromes.
Evalution of benomyl and carbendazim in the vivo aneuploidy/micronucleus assay in BDF1 mouse bone marrow

Abstract Benomyl and its active metabolite carbendazim were investigated in BDF1 mouse bone marrow to establish whether micronuclei induced by these fungicides are caused by clastogenic or aneugenic events. Micronuclei were evaluated for kinetochores using immunofluorescent antikinetochore antibodies. Kinetochore positive (K + ) micronuclei are likely to arise from chromosome loss since they presumably contain intact kinetochores and are indicative of aneuploidy. Conversely, kinetochore negative (K − ) micronuclei are most likely to contain acentric chromosome fragments arising primarily from clastogenic damage. Benomyl and carbendazim were administered as single oral doses of 0.3, 8.6 or 17.2 mmol/kg (for benomyl, equivalent to 100, 2500 or 5000 mg/kg; for carbendazim, equivalent to 66, 1646 or 3293 mg/kg). Both compounds were positive in the micronucleus test at doses of 8.6 and 17.2 mmol/kg, and an average of 82% (benomyl)_and 87% (carbendazim) of the total micronucleated polychromatic erythrocytes were K + . No effects were seen with either fungicide at 0.3 mmol/kg. These results are analogous to findings with known aneugens such as vincristine but are in contrast to results with classical such as cyclophosphamide. Thus, benomyl and carbendazim induced micronuclei in mmouse bone marrow cells primarily throygh an aneugenic mechanism.
Predictive Models of Forest Dynamics

Dynamic global vegetation models (DGVMs) have shown that forest dynamics could dramatically alter the response of the global climate system to increased atmospheric carbon dioxide over the next century. But there is little agreement between different DGVMs, making forest dynamics one of the greatest sources of uncertainty in predicting future climate. DGVM predictions could be strengthened by integrating the ecological realities of biodiversity and height-structured competition for light, facilitated by recent advances in the mathematics of forest modeling, ecological understanding of diverse forest communities, and the availability of forest inventory data.
Polyethism in workers of the AntMyrmica part II

Variation in worker locomotor activity and worker behaviour inMyrmica rubra microgyna has been experimentally investigated, with the following results.
Stochastic models of tumor growth and the probability of elimination by cytotoxic cells.

The probability of tumor extinction due to the action of cytotoxic cell populations is investigated by several one dimensional stochastic models of the population growth and elimination processes of a tumor. The several models are made necessary by the nonlinearity of the processes and the different parameter ranges explored.
Hologram Bandwidth Reduction by Space–Time Multiplexing*

This paper describes a method for reducing the spatial bandwidth of holograms by use of a moving dispersion structure between the object and the hologram. The theory developed in the paper includes the Haines–Brumm stationary dispersion structure as a special case. The added flexibility permits the use of simple dispersion structures that can be easily reproduced and scaled, and relatively complicated motions to produce virtual images without auxiliary optics.
A long-term follow-up of acetazolamide (diamox) in the treatment of epilepsy.

SUMMARY Two hundred and seventy-seven patients with epilepsy treated with diamox alone or in combination with other drugs have been described. All patients had been followed for at least three years. The treatment benefited some patients subject to myoclonic and akinetic seizures. It seemed of little benefit in the group of psychomotor or focal seizures. On a short-term basis diamox proved to be at least as effective as the other recognized drugs in controlling petit mal or petit mal and grand mal seizures. However, under prolonged treatment diamox lost much of its effectiveness. A similar decline in the percentage of effective control was observed when tridione was used in the same group of patients. The need for longitudinal studies to give an adequate picture of the usefulness of anti-epileptic drugs is further emphasized. RESUME Description de 277 malades epileptiques traites par le diamox seul ou en combinaison avec d'autres medicaments. Tous ces malades ont ete suivis pendant trois ans au moins. Le traitement a ete favorable a quelques malades sujets a des crises myocloniques et akinetiques. Il semble qu'il y ait eu peu d'amelioration dans le groupe de crises psychomotrices ou focales. Sur la base d'une courte periode, le diamox s'est revele au moins aussi efficace que les autres medicaments reconnus dans le traitement des crises de petit mal et de grand mal du type centrencephalique. Toutefois le diamox perd une grande partie de son efficacite lors d'un traitement prolonge. Un abaissement de meme genre du pourcentage des traitements efficaces a ete observe lors de l'administration de tridione au meme groupe de malades. Les auteurs insistent ensuite sur la necessite de poursuivre les etudes envisageant l'obtention d'une image adequate de l'utilite des medicaments anti-epileptiques.
Methamphetamine Use Among San Diego County Arrestees

Abstract Between 1987 and 2003, an objective measure of recent drug use from a high-risk group was collected as part of a federally-funded program called ADAM (Arrestee Drug Abuse Monitoring). The information collected as part of this project supplemented other self-report data collected across the country with the general population. San Diego County was one of the original ADAM sites, and with local funding support was able to maintain the essential aspects of the program uninterrupted when national support was discontinued. In May 2006. the results of data collected in calendar year 2005 as part of a standard interview with adult and juvenile arrestees, urinalysis. as well as a methamphetamine (meth) addendum were presented at the Substance Abuse Research Consortium (SARC) meeting in Pasadena, California. This article provides a summary of these descriptive data, including a profile of recent meth users, reasons for initiating and continuing use. patterns of use, and trends in use over time. Additional...
Predictability of morphological gradients in the tapeworm, Hymenolepis diminuta

The strobila of an adult tapeworm represents a continual gradient of developmental stages from immature to gravid proglottids. The purpose of this study was to determine if organogenesis (as measured by the developmental gradient) in tapeworms within a single host and among different hosts occurred at the same rates. Rats were infected with Hymenolepis diminuta and the tapeworms were recovered 20 days post-infection. The total number of proglottids in each worm was determined, and five 'benchmarks' of organogenesis were quantified. The data demonstrated that organogenesis in worms from a single host occurred at a relatively constant rate, but that rates in tapeworms from different hosts were different.
Computational Efficiency: A Common Organizing Principle for Parallel Computer Maps and Brain Maps?

It is well-known that neural responses in particular brain regions are spatially organized, but no general principles have been developed that relate the structure of a brain map to the nature of the associated computation. On parallel computers, maps of a sort quite similar to brain maps arise when a computation is distributed across multiple processors. In this paper we will discuss the relationship between maps and computations on these computers and suggest how similar considerations might also apply to maps in the brain.
Interaction of Indentation‐Induced Cracks on Single‐Crystal Silicon Carbide

Due to its transparency, high hardness, and low density, single-crystal silicon carbide (SC-SiC) is a candidate material for transparent armor and bullet-proof windows. This manuscript explores the fracture anisotropy of the basal plane of two common HCP polytypes: 4H-SiC and 6H-SiC. Through single indentation, sequential indentation, and theoretical calculations, the primary and secondary cleavage directions are shown to be and , respectively. It is also shown that no appreciable tertiary cleavage direction exists on the basal plane. This investigation is the first to report how single-crystal silicon carbide responds to multiple indentation. The results have fundamental value in modeling its fracture behavior.