cssi/SciSciGPT-SciSciNet huggingface dataset:
Improved frame-to-frame pose tracking during vision-only SLAM/SFM with a tumbling target

A hybrid algorithm for real-time frame-to-frame pose estimation during monocular vision-only SLAM/SFM is presented. The algorithm combines concepts from two existing approaches to pose tracking, Bayesian estimation methods and measurement inversion techniques, to achieve in real-time a feasible, smooth estimate of the relative pose between a robotic platform and a tumbling target. It is assumed that no a priori information about the target is available, and that only a monocular camera is available for measuring the relative motion of the target with respect to the robotic platform. The rationale for a hybrid approach is explained, and an algorithm is presented. A specific implementation using a modified Rao-Blackwellised particle filter is described and tested. Results from both numerical simulations and field experiments are included which demonstrate the performance and viability of the hybrid approach. The hybrid approach to pose estimation described here is applicable regardless of the method by which the map/reconstruction is estimated.
Responses of Nasonovia ribisnigri (Homoptera: Aphididae) to susceptible and resistant lettuce.

Nymphs and alates of aphid Nasonovia ribisnigri (Mosley) (Homoptera: Aphididae) were tested on 10 lettuce cultivars with N. ribisnigri resistance gene Nr and 18 cultivars without the resistance gene in various bioassays. Bioassays used whole plants, leaf discs, or leaf cages to determine susceptibility of commercial lettuce cultivars to N. ribisnigri infestation and to evaluate screening methods for breeding lettuce resistance to N. ribisnigri. Resistant and susceptible plants were separated in 3 d when using whole plant bioassays. Long-term (≥7 d) no-choice tests using leaf cages or whole plants resulted in no survival of N. ribisnigri on resistant plants, indicating great promise of the Nr gene for management of N. ribisnigri. Effective screening was achieved in both no-choice tests where resistant or susceptible intact plants were tested separately in groups or individually and in choice tests where susceptible and resistant plants were intermixed. Leaf discs bioassays were not suitable for resistance screening. All lettuce cultivars without the resistance gene were suitable hosts for N. ribisnigri, indicating the great importance of this pest to lettuce production and the urgency in developing resistant lettuce cultivars to manage N. ribisnigri.
Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in Human Breast Cancer

Background: Numerous studies have demonstrated that the levels of prostaglandins are greater in various cancers, including breast cancer and colon cancer, than in normal tissues. In particular, the inducible form of cyclooxygenase (COX), the rate-limiting enzyme in prostaglandin biosynthesis, is overexpressed in colon tumors. Epidemiologic studies have demonstrated that the use of aspirin or other nonsteroidal antiinflammatory drugs (NSAIDs) can reduce the risk of colon cancer and, to a lesser extent, the risk of breast cancer. NSAIDs are known to inhibit COX, suggesting that the beneficial effect of NSAIDs in colon cancer may be related to COX overexpression in this disease. This possibility led us to ask whether COX is also overexpressed in breast cancers. Methods: Surgical specimens from 44 patients with breast cancer who had undergone lumpectomy or mastectomy were analyzed by immunoblot analysis and immunohistochemical analysis to determine the expression profile of the constitutively expressed form of cyclooxygenase (COX-1) and the inducible form (COX-2); the specimens from 14 patients included normal breast tissue. Results: Expression of COX-1 protein was substantially higher in 30 of 44 tumor samples than in any of the 14 normal tissue specimens. Immunoblot analysis revealed extremely high levels of COX-2 protein in two tumor samples. Immunohistochemical staining of specimens that expressed COX-1 and/or COX-2 revealed that COX-1 was localized in stromal cells adjacent to the tumor but not in tumor cells. In contrast, COX-2 was localized primarily in tumor cells but also appeared in stromal cells. Conclusion : Our results suggest that overexpression of COX may not be unique to colon cancer and may be a feature common to other epithelial tumors.
Total colonic manometry as a guide for surgical management of functional colonic obstruction: Preliminary results

Abstract Background/Purpose: Functional colonic obstruction (pseudo-obstruction) encompasses a broad group of motility disorders. Medical management of colonic pseudo-obstruction is complex and often fails, leading to surgical referral. In most cases (excepting Hirschsprung's disease) the surgeon is unable to precisely localize the area of functional obstruction. Total colonic manometry can directly measure intraluminal pressures and contractile function along the entire length of the colon. The authors propose that total colonic manometry can be used by the pediatric surgeon to guide the timing and extent of surgical therapy in refractory functional colonic obstruction. Methods: Four patients were evaluated for functional colonic obstruction. All underwent barium enema and rectal biopsy with a diagnosis of Hirschsprung's disease in one patient. All patients underwent colonoscopy and total colonic manometry. Manometric tracings were obtained while fasting, after feeding, and after pharmacologic stimulation both preoperatively (n = 4) and postoperatively (n = 3). Results: Total colonic manometry identified an abrupt end of normal peristalsis in 2 of the non-Hirschsprung's patients (one in the proximal colon and one in the transverse colon). Medical therapy failed in both of these patients, and they underwent diverting ostomy proximal to the loss of normal peristalsis. The third non-Hirschsprung's patient essentially had normal manometry and was able to have her colon decompressed successfully on a laxative regimen. Repeat manometry after colonic decompression showed return of normal peristalsis in 2 of these patients and continued abnormal peristaltic activity in the third. Definitive surgical intervention based on the results of total colonic manometry was performed on the latter. All 3 patients achieved normal continence. A fourth patient had Hirschsprung's disease confirmed by rectal biopsy and underwent a 1-stage neonatal modified Duhamel procedure, which was complicated by postoperative functional obstruction. Manometry showed a lack of peristaltic function beginning in the right colon. An ileostomy was performed, and timing of ileostomy closure was guided by the return of normal colonic peristalsis seen on manometry. Conclusions: These initial cases show the utility of total colonic manometry in the management of colonic pseudo-obstruction syndromes. In addition to its diagnostic utility, direct measurement of colonic motor activity can be valuable in deciding the need for and timing of diversion, the extent of resection, and the suitability of the patient for restoring bowel continuity. In Hirschsprung's disease, total colonic manometry can potentially be used to determine suitability for primary neonatal pull-through versus a staged approach. J Pediatr Surg 36:1757-1763. Copyright © 2001 by W.B. Saunders Company.
Evolution of interactions in family-structured populations: mixed mating models.

The effect of inbreeding on sociality is studied theoretically for the evolution of interactions between siblings in certain mixed mating systems that give rise to inbreeding: sib with random mating and selfing with random mating. Two approaches are taken. First, specific models of altruism are studied for the various mating systems. In the case of the additive model, inbreeding facilitates the evolution of altruistic genes. Likewise, for the multiplicative model this is usually the case, as long as the costs of altruism are not too great. Second, the case of total altruism, in which the gene has zero individual fitness but increases the fitness of associates, is studied for a general fitness formulation. In this case, inbreeding often retards the ability of such genes to increase when rare, and the equilibrium frequency of those recessive genes that can increase is totally independent of the mating system and, consequently, of the amount of inbreeding. It appears from the results presented that inbreeding facilitates most forms of altruism, but retards extreme altruism. These results stem from the fact that inbreeding increases the within-family relatedness by increasing the between-family variance in allele frequency. In most cases this facilitates altruism. However, in the case of total altruism, only heterozygotes can pass on the altruistic allele, and inbreeding tends to decrease this heterozygote class. In either case, the important effect of inbreeding lies in altering the genotypic distribution of the interactions.
Early Implementation of Palliative Care Can Improve Patient Outcomes

Patients with cancer experience many complex issues throughout the trajectory of the disease. These range from the physical consequences of cancer and treatment to the psychological, social, and spiritual issues associated with living with the disease. An individualized, comprehensive, and interdisciplinary approach is needed to reduce patient suffering and ensure appropriate symptom management and support from the time of first diagnosis to end of life. Data from randomized clinical trials prove that patients provided with early palliative care can experience relief of symptoms and improvements in quality of life, mood, satisfaction, resource use, and advanced care planning. Professional organizations such as ASCO have begun to develop recommendations that integrate palliative care into standard oncologic care from the time a person is diagnosed with metastatic or advanced cancer. NCCN has a palliative care guideline that recommends early and ongoing assessment of palliative care needs and referral to specialist palliative care services in more complex cases. In turn, oncologists need to consider how best to screen patients and integrate early palliative care with routine oncologic care, within the context of their busy clinics, to ensure that patients, families, and caregivers receive timely support.
Modifying Wear Life of All-Cotton Fabrics : Part I: Liquid Ammonia Treatment and Durable Press Finish

The modifying effects of liquid ammonia as a final finishing treatment and as a pretreatment for durable press finish on wear performance of all-cotton broadcloth were investigated. Abrasion resistance and appearance retention were taken as indicators of wear life. Abrasion was monitored by Stoll flex abrasion in dry and wet conditions and repeated laundering. Abrasion resistance was assessed from residual breaking strength and elongation-at-break behavior of fabrics, whereas wrinkle recovery, dimensional stability, and whiteness retention gave a measure of appearance retention qualities. Liquid ammonia improved the tensile strength and Stoll flex abrasion in dry condition, as well as dimensional stability of cotton broad cloth. As a pretreatment for durable press finish, liquid ammonia significantly improved abrasion resistance, tensile strength retention, wrinkle recovery, and di mensional stability in cotton broadcloth relative to durable press treatment by itself.
Wind Sea Growth and Dissipation in the Open Ocean

Abstract Wind sea growth and dissipation in a swell-dominated, open ocean environment is investigated to explore the use of wave parameters in air–sea process modeling. Wind, wave, and whitecap observations are used from the Gulf of Alaska surface scatter and air–sea interaction experiment (Critical Sea Test-7, Phase 2), conducted 24 February through 1 March 1992. Wind sea components are extracted from buoy directional wave spectra using an inverted catchment area approach for peak isolation with both wave age criteria and an equilibrium range threshold used to classify the wind sea spectral domain. Dimensionless wind sea energy is found to scale with inverse wave age independently of swell. However, wind trend causes significant variations, such as underdeveloped seas during rising winds. These important effects are neglected in wind-forced air–sea process models. The total rate of wave energy dissipation is conveniently estimated using concepts from the Phillips equilibrium range theory. Replacing wind ...
Chapter 17 Left- and Mixed-Handedness and Criminality: Explanations for a Probable Relationship

Publisher Summary This chapter reviews the literature related to handedness and criminality. There is a general support for the hypothesis that left- and mixed-handers are somewhat more prone toward criminality than right-handers. The chapter presents various theoretical explanations for why such a relationship should exist. The most plausible explanations for a handedness–criminality relationship seem to be based upon the knowledge about how the two hemispheres differentially respond to stimuli both cognitively and emotionally. There is considerable support for the hypothesis that left- and mixed-handers are slightly more likely to engage in crime than right-handers, at least among males. Research suggests that the most reasonable explanations for why even a modest relationship should exist between handedness and criminality are neurologically based. Such explanations have focused on differences in how the two hemispheres respond to incoming stimuli. Compared to the left hemisphere, the right hemisphere appears to be (1) less capable of handling language and other forms of logical–serial thought, (2) more emotional, especially with reference to negative emotions, and (3) may be less motivated by social influences than by self-interest. The chapter offers a theoretical model that suggests that three identifiable parts of the brain are altered by being exposed to sex hormones, one of which is the neocortex.
Is What’s Hot in Reading What Should be Important for Reading Instruction?

For years one of the most anticipated events in my professional life has been the annual publication of the What’s Hot, What’s Not survey by Jack Cassidy and his colleagues. As a longtime responden...
Optimal atlas construction through hierarchical image registration

Atlases (digital or otherwise) are common in medicine. However, there is no standard framework for creating them from medical images. One traditional approach is to pick a representative subject and then proceed to label structures/regions of interest in this image. Another is to create a "mean" or average subject. Atlases may also contain more than a single representative (e.g., the Visible Human contains both a male and a female data set). Other criteria besides gender may be used as well, and the atlas may contain many examples for a given criterion. In this work, we propose that atlases be created in an optimal manner using a well-established graph theoretic approach using a min spanning tree (or more generally, a collection of them). The resulting atlases may contain many examples for a given criterion. In fact, our framework allows for the addition of new subjects to the atlas to allow it to evolve over time. Furthermore, one can apply segmentation methods to the graph (e.g., graph-cut, fuzzy connectedness, or cluster analysis) which allow it to be separated into "sub-atlases" as it evolves. We demonstrate our method by applying it to 50 3D CT data sets of the chest region, and by comparing it to a number of traditional methods using measures such as Mean Squared Difference, Mattes Mutual Information, and Correlation, and for rigid registration. Our results demonstrate that optimal atlases can be constructed in this manner and outperform other methods of construction using freely available software.
An Olmec Design on an Early Peruvian Vessel

Although it has been considered possible that certain elements originating in the Olmec culture of Mexico were added to older Peruvian traditions to produce the Chavin civilization, the radiocarbon dates on Olmec and Chavin make them approximately coeval. A black-ware bottle found at Kotosh, in the central Peruvian highlands, bears a design of an ear of maize, a motif of probable Olmec origin. Since this vessel was from a phase immediately preceding the Chavin horizon, it is suggested that the Olmec culture began earlier than did Chavin and, in fact, could have been the progenitor for civilization in the Andean Area.
An innovative hydrodynamic separation technology (HDS) for water pretreatment: harvesting neutrally buoyant particles effectively

This paper describes the feasibility and application of a fluidic-based technology, called hydrodynamic separation (HDS), to separate suspended particles from liquid. It uses customized fluid flow patterns in a curved channel to create a pair of Dean vortexes that focus particles into a concentrated band near one channel wall. A splitter at the end of the channel divides the flow into a clean effluent stream and a concentrate stream. The focusing of particles is primarily due to a combination of hydrodynamic forces (drag, virtual mass, and shear), which causes a size rather than density dependent separation. This enables separation of particles with densities identical or close to that of their surrounding fluid, allowing this technology to be especially useful in situations where traditional methods are challenged, such as removal of buoyant particulates from primary clarifiers or separation of unsettleable activated sludge in secondary clarifiers. We tested HDS-based separators with samples that include neutrally buoyant polystyrene beads, activated sludge, primary clarifier effluent and powdered activated carbon to demonstrate its efficacy. In each case, high separation efficiency was achieved which reaffirmed our commitments to evolve HDS technology into an effective pretreatment solution.
P450-Catalyzed Intramolecular sp3 C–H Amination with Arylsulfonyl Azide Substrates

The direct amination of aliphatic C–H bonds represents a most valuable transformation in organic chemistry. While a number of transition-metal-based catalysts have been developed and investigated for this purpose, the possibility to execute this transformation with biological catalysts has remained largely unexplored. Here, we report that cytochrome P450 enzymes can serve as efficient catalysts for mediating intramolecular benzylic C–H amination reactions in a variety of arylsulfonyl azide compouds. Under optimized conditions, the P450 catalysts were found to support up to 390 total turnovers leading to the formation of the desired sultam products with excellent regioselectivity. In addition, the chiral environment provided by the enzyme active site allowed for the reaction to proceed in a stereo- and enantioselective manner. The C–H amination activity, substrate profile, and enantio/stereoselectivity of these catalysts could be modulated by utilizing enzyme variants with engineered active sites.
Does Negative Mood Confer an Advantage in the Recall of Negative Life Events

Models of depression suggest that depression, which is characterized by sad mood, should confer a recall advantage for negative stimuli, including stressful life events. The current study examined the effects of mood congruent recall on the quantity and accuracy of recall of negative life events. Forty-two college students received a negative or positive mood induction and then listened to narratives of 11 negative life events which mapped onto a well-known life events checklist measure. One week later, participants returned to the lab, received the same mood induction, and were asked to recall the narratives in open-ended recall and when using the life events checklist as a memory measure. There were no significant group differences on numerous measures of quantity and accuracy of recall including false memories. These results suggest that negative mood does not confer a recall advantage nor disadvantage for narratives of negative life events. Possible implications for depression and recall of negative l...
Effects of Substrate Physical Characteristics and Orientation on Oviposition by Eoreuma loftini (Lepidoptera: Pyralidae)

The effects of substrate physical characteristics and orientation on oviposition by Eoreuma loftini (Dyar) were investigated in the laboratory. Dead sugarcane leaves were strongly preferred over live, green leaves for oviposition. Vertically oriented dead leaves were preferred over horizontally oriented dead leaves. Females oviposited more eggs on rough surfaces than on smooth surfaces. More eggs were laid in leaf crevices and folds than on exposed leaf surfaces. Substrate composition, texture, orientation, and exposure affected egg mass size.
Research and Evaluation that Make a Difference

This chapter reviews the second theme-based strategy of a rights research approach is “research and evaluation that makes a difference.” It provides a historical overview of how social workers historically have used to research and evaluation strategies to “make a difference.” The advanced generalist pubic health model was presented as an integrated model in which prevention and intervention strategies at the micro, mezzo, and macro levels of intervention can be used for the design, planning, and classification of research and evaluation studies. This model incorporates the use of quantitative, qualitative, mixed methods, and alternative research methodologies that have relevance for a rights research approach. Examples of contemporary work on aging and LGBT people involved in the criminal justice system that involved quantitative, qualitative, and participatory action methods to build public awareness and create avenues for advocacy.
The features of Hirschsprung's disease under colonoscopy

Objective To investigate the feature of Hirschsprung's disease (HD) in children under colonoscope.Methods 118 patients of HD between 2000 and 2010 in our hospital were observed and the manifestations under colonoscope were summarized.Result 107 cases were confirmed as HD by colonoscopy.97 patients of HD were complicated by colonitis under colonoscope,and 11 patients were combined with colonic ulcer,10 patients had stercorolith,which had been galetted.7 patients were diagnosed as polyp intestinal.Conclusion The alteration of colon plica and diversity of the diameter in patients of HD can be observed under colonoscopy,and the complications before operation can be displayed directly.
Contact lenses and refractive surgery. Addressing patient problems and concerns.

PreviewMany patients who want alternatives to eyeglasses turn to their primary care physician for advice regarding contact lenses or refractive surgery. Dr Nathenson describes the indications for and potential problems of these methods of correcting refractive errors.
Nonmedical use of prescription drugs and peer norms among adolescents by race/ethnicity

Background: The study purpose was to assess the effect peer norms have on nonmedical use of prescription drugs (i.e., pain relievers, stimulants, tranquilizers, sedatives, and all four drug classes...
Post-prostatectomy continence in the parkinsonian patient: the significance of poor voluntary sphincter control

A retrospective urodynamic study of 50 parkinsonian patients was done to determine the incidence and causes of post-prostatectomy incontinence. At presentation 22 per cent of the patients were incontinent. In 36 patients who underwent transurethral prostatectomy the incontinence rate was 17 per cent preoperatively and 28 per cent postoperatively. There was a clear association between normal voluntary sphincter control and urinary continence. After transurethral prostatectomy 5 of 6 patients continent preoperatively (83 per cent) who had abnormal sphincter control became incontinent compared to 1 of 24 (4.2 per cent) who had normal sphincter control. We conclude that the major risk of incontinence following prostatectomy in the parkinsonian patient is associated with lack of voluntary sphincter control.
Radiography of articular disorders in the foot

The author reviews various pedal articulations, as well as certain clinical manifestations with which these may be pathologic. Pertinent anatomy is described. Individual as well as multiple articular disorders in the foot are illustrated.
Cookoff Modeling of a WIPP waste drum (68660)

A waste drum located 2150 feet underground may have been the root cause of a radiation leak on February 14, 2014. Information provided to the WIPP Technical Assessment Team (TAT) was used to describe the approximate content of the drum, which included an organic cat litter (Swheat Scoop®, or Swheat) composed of 100% wheat products. The drum also contained various nitrate salts, oxalic acid, and a nitric acid solution that was neutralized with triethanolamine (TEA). CTH-TIGER was used with the approximate drum contents to specify the products for an exothermic reaction for the drum. If an inorganic adsorbent such as zeolite had been used in lieu of the kitty litter, the overall reaction would have been endothermic. Dilution with a zeolite adsorbent might be a useful method to remediate drums containing organic kitty litter. SIERRA THERMAL was used to calculate the pressurization and ignition of the drum. A baseline simulation of drum 68660 was performed by assuming a background heat source of 0.5-10 W of unknown origin. The 0.5 W source could be representative of heat generated by radioactive decay. The drum ignited after about 70 days. Gas generation at ignition was predicted to be 300-500 psig with a sealedmore » drum (no vent). At ignition, the wall temperature increases modestly by about 1°C, demonstrating that heating would not be apparent prior to ignition. The ignition location was predicted to be about 0.43 meters above the bottom center portion of the drum. At ignition only 3-5 kg (out of 71.6 kg total) has been converted into gas, indicating that most of the material remained available for post-ignition reaction.« less
Money, Banking and Financial Sophistication

During the period 1850–1913, the banking systems of Europe grew very rapidly by historical standards. The typical pattern was for the money stock to grow considerably faster than nominal gross national (or domestic) output, as we illustrate below, and as we noted in Chapter 3, real gross output also grew rapidly by historical comparison throughout much of Europe during this period. Indeed, the money supply grew more rapidly than nominal output in every country for which we have the appropriate data, except the United Kingdom. This finding implies that velocity — that is, the average number of times a unit of domestic currency changes hands — fell during the period 1850–1913.1 The period also features price levels that fell about as often as they rose, so that growth rates of money were also generally much in excess of rates of inflation. It follows that the rapidly expanding banking systems on the Continent were filling a need, at the same time many of the economies were industrializing at unprecedented rates, by providing new financial services at an equally unprecedented rate.
Dynamic rule generation for SCADA intrusion detection

Security of Supervisory Control and Data Acquisition (SCADA) systems remains a vital issue due to the criticality of the systems they control. They are used in various critical infrastructures, including electric power, oil & gas and others. The protocols used in this domain were designed to satisfy operational requirements without much consideration for security issues. Most SCADA protocols in use today have the ability to transport control messages over TCP/IP networks, leaving them open to attacks that may have a catastrophic impact on the physical systems they control. This paper describes a research effort to improve the current state intrusion detection solutions for SCADA systems. Intrusion Detection Systems (IDS) used in this domain are typically extensions of IT tools, such as Snort, that have been extended with generic static signatures. The main limitation of this approach is its inability to adapt to system changes and it only offers partial support for deep-packet inspection. The proposed approach improves on existing IDS solutions by developing a framework that allows (i) dynamic rule generation and (ii) fine-tuned deep-packet inspection. A simple language grammar allows network engineers to describe system characteristics that include network topology, protocol and the roles of the different control nodes. A compiler, instrumented with SCADA-specific semantic rules, recognizes monitoring needs and generates network signatures that are specific to the system monitored by the IDS. An organization using our approach has the ability to adapt to system changes by simply updating the system description and its monitoring needs.
Influence of scan strategy and process parameters on microstructure and its optimization in additively manufactured nickel alloy 625 via laser powder bed fusion

Laser powder bed fusion (L-PBF) as an additive manufacturing process produces nearly fully dense nickel alloy 625 (IN625) parts with complex features. L-PBF generates surfaces and microstructure through directional solidification that can be controlled by scan strategies and selection of process parameters. This study provides experimental investigations on microstructure formation including sizes of cellular grains and growth directions of columnar grains on the nickel alloy 625 test coupons. The effects of process parameters including laser power, scan velocity, hatch distance, and scan strategy that produce various solidification cooling rates and thermal gradients during the process, which also contribute to resultant microstructure, have been analyzed. Optimization studies are conducted on several objectives to improve the productivity while controlling the process effects on the resultant microstructure using response surface regression, desirability functions, and multi-objective genetic algorithm optimization.
Bioassay and pharmacologic evaluation of the adenosine hypothesis.

Our approach to the mechanism of hypoxic, ischemic, and exercise dilation has differed from that of Berne and Rubio. We have mainly used bioassay and pharmacological techniques. The data generated by these techniques support the adenosine hypothesis1 for regulation of blood flow in cardiac and skeletal muscle and in addition suggest a contributory role for AMP in cardiac hypoxic dilation.
The Number of the Beast in Revelation 13 in Light of Papyri, Graffiti, and Inscriptions

Revelation’s portrayal of a tyrannical beast concludes with a riddle, which identifies the beast’s number as 666 (Rev. 13:18). Among the factors that complicate the interpretation of the riddle are...
Malignancy Risk and Recurrence with Psoriasis and its Treatments: A Concise Update

Psoriasis is a common inflammatory cutaneous disease that affects approximately 120 million people worldwide. Systemic treatments have significantly improved disease burden, but concerns persist regarding their association with increased risk of malignancy. Patients with psoriasis have a slightly elevated baseline risk of lymphoproliferative diseases. Studies on methotrexate and cyclosporine, as well as older biological agents such as tumor necrosis factor inhibitors, have found no increased risk of non-cutaneous solid tumors; however, positive associations between cutaneous squamous cell carcinomas and certain therapies have been found. There is conflicting evidence regarding the risk of lymphoma and melanoma. Further studies are needed to determine the long-term safety of newer psoriasis treatments (interleukin [IL]-12/23, IL-17, Janus kinase 1/3, and phosphodiesterase-4 inhibitors), specifically their safety in patients with a history of cancer. This review summarizes the most recent studies on malignancy risk from psoriasis, and its treatments in patients and cancer survivors, with the highest available level of evidence.
Caribfunk Technique: A New Feminist/Womanist Futuristic Technology in Black Dance Studies in Higher Education

This chapter engages in storytelling/narrative to raise questions concerning the place of the black (female) body in society. Informed by her growing up in the Bahamas, a former British colony, A’Keitha Carey established CaribFunk™: a fusion dance technology that incorporates traditional and social Afro-Caribbean, classical ballet, modern, and fitness elements. She developed this technique as one that identifies that the body is a site of knowledge, illuminating the transformative performances of the pelvis. She discusses the exclusion of Afro-Diasporic movements and aesthetics in dance curriculum and the future of dance studies using a Black feminist lens.
Relative prevalence of limb-girdle muscular dystrophy subtypes at the UC Irvine MDA Clinic (P1.118)

Objective: To determine the relative prevalence of each LGMD subtype at the UC Irvine MDA clinic. Background: Limb Girdle Muscular Dystrophies (LGMDs) are a heterogeneous group of inherited muscle disorders characterized by predominant weakness in the shoulder and hip girdles. They can be inherited in an autosomal dominant (designated as LGMD1) or autosomal recessive (designated as LGMD2) pattern. Currently, there are at least 8 LGMD1 subtypes (labeled LGMD1A-H) and 23 LGMD2 subtypes (labeled LGMD2A-W). Prior epidemiologic studies have shown that calpain-related LGMD2A is the most common subtype in the United States and in the world. Our personal experience suggests that dysferlin-related LGMD2B may be more common than LGMD2A at the UCI MDA clinic. We hypothesized that this may be due to a higher percent of Hispanic patients in the region and perhaps due to a founder mutation in this population. Design/Methods: We reviewed all genetically confirmed cases of LGMD at the UC Irvine MDA clinic from January 2010 to October 2016 to determine the relative prevalence of each subtype. Results: Forty-five cases were genetically characterized. LGMD2V (Pompe disease) was the most common subtype in our study, with a relative prevalence of 36% (n=16). This may, however, be due to an ascertainment bias, given that we have an organized large Pompe clinic in the country. This was followed by LGMD2B (22%, n=10) and LGMD2A (11%, n=5). Seventy percent of LGMD2B cases are of Hispanic descent, of which 57% have the homozygous pathogenic variant c.4253G>A in the DYSF gene, suggesting a founder mutation. Conclusions: Our data appears to support the hypothesis that LGMD2B is more common than LGMD2A at the UC Irvine MDA clinic. This finding is likely due to a larger Hispanic population in this region and a possible founder mutation. However, our sample size is small and further data is needed to draw firm conclusions. Disclosure: Dr. Lai has nothing to disclose. Dr. Goyal has nothing to disclose. Dr. Mozaffar has received personal compensation for activities with Sanofi Genzyme, Grifols, Amicus, Biomarin, Idera Pharmaceuticals and Ultragenyx. Dr. Mozaffar has received research support from Cytokinetics, Alexion, Amicus, Biomarin, Grifols, GlaxoSmithKline, Ultragenyx, and Novartis.
Increasing provider awareness of and recommendations for yoga and meditation classes for cancer patients

The purpose of the current study was to (1) assess healthcare providers’ beliefs about and referral patterns to yoga and meditation services, and (2) evaluate the effectiveness of a brief yoga/meditation educational presentation to increase providers’ intent to recommend these programs. A brief 5-min presentation regarding the benefits of yoga and meditation for cancer patients and instruction about referring and enrolling patients was delivered in four different oncology settings: breast, gynecologic, radiation, and surgical. Healthcare provider participants filled out pre- and post-surveys assessing knowledge and attitudes surrounding yoga and meditation classes. A total of 40 healthcare providers were surveyed, consisting of 18 physicians, 12 nurses, six nurse practitioners, two physician assistants, one pharmacist, and one clinical researcher. Of these 40 healthcare providers, 43% were unaware at baseline that yoga and meditation classes were offered through the cancer center and 55% responded that they rarely or never recommend yoga or meditation for patients. Following a brief presentation about the benefits of yoga and meditation for cancer patients, 90% of providers stated they would be more likely to recommend these services to patients in the future. There was a significant (p < 0.01) increase in providers from pre- to post-presentation (65 to 85%) stating they strongly believe yoga and meditation can provide physical or emotional benefits for their patients. These data demonstrate that a brief educational intervention about yoga and meditation for cancer patients is effective at significantly increasing provider knowledge about the benefits of these therapeutic modalities, with a majority indicating they are more likely to recommend these services in the future. Increasing provider awareness regarding the health-promoting benefits of such supportive services for cancer patients could result in greater service utilization as well as physical and emotional benefits for patients.
Inferences of Organization and Meaning

The process of cognition usually begins with perception because perception involves registering outside stimuli and also drawing many kinds of inferences from them. We want to consider the inference process carefully because it underlies the process of gathering information about products. One of the oldest questions in psychology asks how we get from seeing to perceiving. It might seem that these are the same thing, but they are really quite different. Seeing is the process in which the eye reacts to the light that reaches it. The eye sees variations in brightness, possibly color, in endless arrays of shape and form. Perception, on the other hand, uses the same bits and pieces, but now their arrangements produce a level of meaning, such as “Jimmy playing his tuba marching by with the band.” The process of seeing is called sensation, whereas the process of understanding what is seen is called perception. Notice that it is not necessarily understanding correctly, but simply some under-standing, some meaning, that makes it perception.
BLACK ROT OF CRUCIFERS

In just over 100 year, the focus on host-pathogen interactions in the black rot disease has shifted gradually from basic aspects of the disease cycle to enzyme production and generegulation at the molecular level. The wealth of information provided through a long history of research makes it an interesting case study. Yet, one first asks whether any one pathosystem can provide a well-rounded view of plant-microbe interactions. Although far from complete, a thorough examination of a single bacterial disease provides a framework for deciphering the language of host-pathogen signalling mechanisms. To understand this system in depth, we take a broad overview of the disease, the pathogen and its natural variability. Then beginning with initial inoculum and epiphytic colonization we consider the steps in breaching a seeries of physical and chemical barriers, responding to the ionic environment, and appropriating nutrients within plant tissues. What attracts the pathogen to the hydathodes at leaf margins? And once having penetrated natural openings, what factors contribute to its movement through the epithem and into the xylem? What enables the black rot pathogen to invade xylame elements whereas closely related leaf spot pathogens are restricted to mesophyll tissues of the same hosts? What triggers the host response? What genes are responsible and how are they regulated? Are these genes interchangeable among pathogens? How have these questions been approached experimentally, and what is now known about them? What are the next steps? A historical perspective is interspersed in this chapter because it provides significant information leading to our current understanding of black rot as a model disease and deepens our comprehension of host-pathogen interactions. Finally, brief comparisons with several other diseases caused by bacteria in the genus. Xanthomonas is made in the attempt to find appropriate areas for generalization.
Rapid Fabrication and Characterization of SERS Substrates

Abstract Surface enhanced Raman spectroscopy (SERS) is a surface-sensitive detection technique that dramatically increases the scattering signals of the analytes compared to traditional Raman spectroscopy. Rapid and low-cost fabrication of SERS substrates with easily tunable features remains a challenge, although many SERS substrates with high enhancement factors (EF) were investigated. Here, we report a novel and rapid approach of fabricating SERS substrates using ultrasonic vibration assisted nanomachining. Grids patterns with easily tuned dimensions were fabricated on PMMA surfaces. SERS substrates were fabricated after coating an 80 nm gold layer on the patterned silicon after reactive ion etching (RIE) using the patterned PMMA as the mask. Probing molecules of R6G with the area density of 2.8 × 10-12 M/mm2 can be detected, achieving an EF of 3.11 × 103. Results show a pattern with higher grids density tends to achieve a higher EF.
On Contradictory Christology: Preliminary Remarks, Notation and Terminology

The following are some preliminary remarks that will set the stage for my individual replies to Timothy Pawl, Thomas McCall, A. J. Cotnoir, and Sara L. Uckelman’s responses to my paper ‘Christ – A Contradiction’. In that paper I advance and defend a contradictory Christology which solves the fundamental ‘problem’ of Christology by holding that Christ is a contradictory being: it is true that Christ is mutable and it is false that Christ is mutable; it is true that Christ is immutable and it is false that Christ is immutable; and so on for other fundamental-problem properties. Familiarity with ‘Christ – A Contradiction’ (and also with background discussion including, e.g., Richard Cross’s discussions of ‘the fundamental philosophical problem’) is assumed.
Michigan’s 11th Congressional District and the Anti-Trump Wave

Michigan’s 11th district, gerrymandered by Republicans in 2012, fell to Democrat Haley Stevens in 2018. The effect of Trump’s trade war on the auto industry compounded the challenge of a Democratic wave election for the Republican candidate, Lena Epstein. District 11 is home to many General Motors managers and a vast array of small businesses tied to the auto industry. An open seat produced by the retirement of an establishment Republican incumbent provided an opportunity that Democrats seized. Republican prospects to hold the seat dimmed further after primary voters chose a candidate closely tied to the President, who is exceptionally unpopular in District 11, which is Michigan’s wealthiest best-educated Congressional district. Although District 11 trends toward Republicans, it is not Trump territory.
The Logics of Gender Justice: State Action on Women’s Rights around the World

Htun and Weldon provide a truly extraordinary analysis of global trends in women’s rights. Relying upon an original database and extensive field research, they empirically document how gender equal...
Applying a User-Centered Method to Develop 3D Gestural Inputs for In-Vehicle Tasks:

Gestures are a natural input method for human communication and may be effective for drivers to interact with in-vehicle infotainment systems (IVIS). Most of the existing work on gesture-based huma...
Effect of a Virtual Pharmacy Review Program: A Population Health Case Study

INTRODUCTION: The growing emphasis on value-based health care has created a need for innovative population health management strategies. Pharmacists are underused resources for implementation of me...
Trophic redundancy and predator size class structure drive differences in kelp forest ecosystem dynamics

Ecosystems are changing at alarming rates because of climate change and a wide variety of other anthropogenic stressors. These stressors have the potential to cause phase shifts to less productive ecosystems. A major challenge for ecologists is to identify ecosystem attributes that enhance resilience and can buffer systems from shifts to less desirable alternative states. In this study, we used the Northern Channel Islands, California, as a model kelp forest ecosystem that had been perturbed from the loss of an important sea star predator due to a sea star wasting disease. To determine the mechanisms that prevent phase shifts from productive kelp forests to less productive urchin barrens, we compared pre- and postdisease predator assemblages as predictors of purple urchin densities. We found that prior to the onset of the disease outbreak, the sunflower sea star exerted strong predation pressures and was able to suppress purple urchin populations effectively. After the disease outbreak, which functionally extirpated the sunflower star, we found that the ecosystem response-urchin and algal abundances-depended on the abundance and/or size of remaining predator species. Inside Marine Protected Areas (MPAs), the large numbers and sizes of other urchin predators suppressed purple urchin populations resulting in kelp and understory algal growth. Outside of the MPAs, where these alternative urchin predators are fished, less abundant, and smaller, urchin populations grew dramatically in the absence of sunflower stars resulting in less kelp at these locations. Our results demonstrate that protected trophic redundancy inside MPAs creates a net of stability that could limit kelp forest ecosystem phase shifts to less desirable, alternative states when perturbed. This highlights the importance of harboring diversity and managing predator guilds.
Penetrating Extremity Trauma Endovascular versus Open Repair

Penetrating extremity trauma (PET) accounts for an estimated 5–15% of trauma with vascular injury and these injuries are accountable for a significant percentage of trauma-related deaths. Historically, vascular injuries were best treated by open repair. While a defined selection criteria and a comprehensive algorithm have not been validated, the advancement of endovascular techniques, embolotherapy, and stent grafting have become viable options for the treatment of penetrating arterial extremity trauma in select patients. Advantages endovascular repair offers include decreasing mortality and morbidity associated with open repair, decreasing blood loss, decreasing iatrogenic injury such as nerve injury, and lower rate of wound infection. Patients stability, type of vascular injury, and lesion location are main factors help deciding between endovascular and open repair. Patient selection between endovascular and open repair should be determined by on a case-by-case situation, individual hospital guidelines, a multidisciplinary approach, and technical expertise.