cssi/SciSciGPT-SciSciNet huggingface dataset:
Using Intraoperative Pelvic Landmarks for Acetabular Component Placement in Total Hip Arthroplasty

Dislocation after total hip arthroplasty is frequently due to acetabular malpositioning. Positioning of the acetabular component using anatomical land- marks may reduce the incidence of dislocation from improper acetabular orienta- tion. The pelvis provides 3 bony landmarks (ilium, superior pubic ramus, and superior acetabulum), which, when used to define a plane, allows cup orientation in abduction and version. Landmarks evaluated in 24 cadaveric acetabuli allowed slightly increased abduction and anteversion of the cup, compared with native acetabuli. Six hundred seventeen primary total hip arthroplasties were performed between 1996 and 2003 using this technique. Mean cup abduction was 44.48 with 13.28 of anteversion. This technique allows satisfactory reproducible cup orientation based on individual pelvic morphology. Review of patient outcome data suggest high patient satisfaction and lower dislocation rate without additional equipment, time, or cost. Key words: pelvic landmarks, acetabular component, total hip arthroplasty.
Basicranial influence on overall cranial shape.

This study examines the extent to which the major dimensions of the cranial base (maximum length, maximum breadth, and flexion) interact with brain volume to influence major proportions of the neurocranium and face. A model is presented for developmental interactions that occur during ontogeny between the brain and the cranial base and neurocranium, and between the neurobasicranial complex (NBC) and the face. The model is tested using exocranial and radiographic measurements of adult crania sampled from five geographically and craniometrically diverse populations. The results indicate that while variations in the breadth, length and flexion of the cranial base are mutually independent, only the maximum breadth of the cranial base (POB) has significant effects on overall cranial proportions, largely through its interactions with brain volume which influence NBC breadth. These interactions also have a slight influence on facial shape because NBC width constrains facial width, and because narrow-faced individuals tend to have antero-posteriorly longer faces relative to facial breadth than wide-faced individuals. Finally, the model highlights how integration between the cranial base and the brain may help to account for the developmental basis of some morphological variations such as occipital bunning. Among modern humans, the degree of posterior projection of the occipital bone appears to be a consequence of having a large brain on a relatively narrow cranial base. Occipital buns in Neanderthals, who have wide cranial bases relative to endocranial volume, may not be entirely homologous with the morphology occasionally evident in Homo sapiens.
Longitudinal evaluation of MPIO-labeled stem cell biodistribution in glioblastoma using high resolution and contrast-enhanced MR imaging at 14.1Tesla

To optimize the development of stem cell (SC)–based therapies for the treatment of glioblastoma (GBM), we compared the pathotropism of 2 SC sources, human mesenchymal stem cells (hMSCs) and fetal neural stem cells (fNSCs), toward 2 orthotopic GBM models, circumscribed U87vIII and highly infiltrative GBM26. High resolution and contrast-enhanced (CE) magnetic resonance imaging (MRI) were performed at 14.1Tesla to longitudinally monitor the in vivo location of hMSCs and fNSCs labeled with the same amount of micron-size particles of iron oxide (MPIO). To assess pathotropism, SCs were injected in the contralateral hemisphere of U87vIII tumor-bearing mice. Both MPIO-labeled SC types exhibited tropism to tumors, first localizing at the tumor edges, then in the tumor masses. MPIO-labeled hMSCs and fNSCs were also injected intratumorally in mice with U87vIII or GBM26 tumors to assess their biodistribution. Both SC types distributed throughout the tumor in both GBM models. Of interest, in the U87vIII model, areas of hyposignal colocalized first with the enhancing regions (ie, regions of high vascular permeability), consistent with SC tropism to vascular endothelial growth factor. In the GBM26 model, no rim of hyposignal was observed, consistent with the infiltrative nature of this tumor. Quantitative analysis of the index of dispersion confirmed that both MPIO-labeled SC types longitudinally distribute inside the tumor masses after intratumoral injection. Histological studies confirmed the MRI results. In summary, our results indicate that hMSCs and fNSCs exhibit similar properties regarding tumor tropism and intratumoral dissemination, highlighting the potential of these 2 SC sources as adequate candidates for SC-based therapies.
Effect of Student-Led Undergraduate Research Experience on Learning and Attitudes --A Practice in An Introductory Materials Science Course

An introductory materials science course has been traditionally taught at Texas A&M University - like at many other universities - through lectures with minimal active student involvement. With this approach, most students just reproduce what they are given and accept it without any challenge or question. The authors have redesigned this course to include an active learning component. While the course consists of lecture-based classes during regular teaching hours to keep the essence of traditional teaching, the authors incorporated a research experience to their class in order to engage students and encourage them to apply the content seen in class to real-word problems with a higher level of expertise. The aim of the study was to discover the effectiveness of the authors’ redesign. We hypothesized that the research experience would facilitate the learning of knowledge content and the enthusiasm for the chosen field of study, i. e. engineering. The results reveal that students in the experimental condition consistently show a greater gain in knowledge, but there is no sufficient evidence suggesting that the research experience increase the student’s enthusiasm to be an engineer.
The Soiling Propensity of Open-End and Ring-Spun Yarns in Jersey Knit Fabrics

Jersey knit fabrics of all cotton and 50/50 cotton-polyester representative of two yarn sizes of open-end and ring-spun yarns were evaluated with regard to their soiling propensity. An oily soil was applied to each fabric in the initial state, after 25 periods of laundering, and after 25 wcar-taundering periods, and subsequently the soiled specimens were exposed to five 45-minute laundering periods in a Launder-Ometer. Reflectance values taken before and after soiling and after laundering served as the basis for findings, which revealed that the condition of the fabric at the time of soiling was related to the amount of soil accepted and released by the fabrics. Additional findings generally pointed to the superior per formance of the ring-spun yarns, the cotton fibers, and the 37s yarns in repelling and releasing the oily soil.
Large-sphere limits of the Mie-scattering functions

For x/n ≫ 1, the following relations between the Mie-scattering functions an (x,m) and bn(x,m) are satisfied: a1 (x,m) = b2 (x,m) = a3 (x,m) = ⋯ = an−1(x,m) = bn(x,m) and b1(x,m) = a2 (x,m) = b3 (x,m) = ⋯ = bn−1 (x,m) = an(x,m) for arbitrary refractive index m. By use of these relations, the Van de Hulst and Deirmendjian conjectures about the x → ∞ behavior of the scattering functions or their linear and bilinear combinations, as well as several new relations, are rigorously proved.
Retaining women in CS with accessible role models

The female role models presented to young women are often unusual individuals who have overcome tremendous social and political obstacles to pursue outstanding careers in mathematics and science. We believe that young women presented with these exceptional role models may actually have their self-confidence undermined because they cannot readily identify with them. At the University of Wisconsin-Parkside (UW-Parkside), we are implementing a project that will employ our own upper-level female computer science (CS) students as half of our laboratory staff in a CS laboratory that is maintained and administrated by our CS students. In this laboratory, women will be as much in control as much as their male counterparts. This non-threatening environment, where women play a prominent role, will communicate to our beginning female students that these roles are realistic and obtainable by them in their college life and in the workplace. We plan to offer our introductory CS sequence to area high school students so that high school girls can benefit from this same experience.
G PROTEIN CONTROL OF MICROTUBULE ASSEMBLY

Microtubules are dynamic polymers required for many aspects of eukaryotic cell function. The interphase microtubule network is essential for intracellular transport, organization, and cell polarization, whereas the mitotic spindle is required for chromosome segregation and cell division. Studies in different areas such as cell migration, mitosis, and asymmetric cell division have shown that Ran, Rho, and heterotrimeric G proteins regulate many aspects of microtubule functions. This review surveys how G protein-signaling coordinates microtubule polymerization and organization with specific cellular activities.
Factors associated with depressive symptoms in non-demented community-dwelling elderly.

OBJECTIVE We examined the risk for depressive symptoms associated with age, education, ethnicity, gender, marital status, apolipoprotein E genotype (APOE) and memory complaints among non-demented elderly (> or = 60 years). DESIGN Cross-sectional study of geriatric patients recruited from a free memory screening offered to the community. SAMPLE This investigation included 506 community-residing elderly subjects who were screened for cognitive impairment and classified as non-demented based on age and education-adjusted Folstein Mini-Mental State Exam (MMSAdj) scores of 24 or greater. RESULTS The prevalence of significant depressive symptoms (Hamilton Depression Rating Scale > or = 12) was 12.1% (N = 61). Increased risk for depression was associated with female gender (OR = 2.3; 95% CI = 1.1-4.8; p < 0.05), Cuban American ethnicity (OR = 4.9; 95% CI = 2.3-10.4; p < 0.0001) and memory complaints (OR = 1.3; 95% CI = 1.2-1.4; p < 0.0001). The APOE allele frequencies in the current sample were 0.07, 0.80 and 0.13 for the epsilon 2, epsilon 3 and epsilon 4 alleles, respectively. CONCLUSIONS The results suggest that signs and symptoms of depression are common among non-demented elderly subjects in the community. In this study, mood disturbances were associated with Cuban American ethnicity, female gender and more memory complaints. Factors that were not confirmed by this study include age, education, marital status and APOE genotype. The observed APOE, epsilon 4 allele frequency of 0.13 supports the normal cognitive classification of the sample.
Fiber type-specific determinants of Vmax for insulin-stimulated muscle glucose uptake in vivo.

The aim of this study was to determine barriers limiting muscle glucose uptake (MGU) during increased glucose flux created by raising blood glucose in the presence of fixed insulin. The determinant...
Van der Waerden at Hamburg

This chapter conveys Van der Waerden work at Hamburg University during 1926–1927 time period.
How accurate is the self-reported diagnosis of chronic bronchitis?

Background: Although it is defined as cough and sputum production for at least 3 months per year for at least 2 consecutive years, difficulties exist in the use of the term chronic bronchitis for clinical diagnosis. In particular, the relationship between diagnosis and symptoms has been difficult to ascertain. Study objectives: To determine, in a large epidemiologic study, the degree to which a new self-reported diagnosis of chronic bronchitis (NCBR) satisfies the symptom criteria for that diagnosis, and to determine the relationship between self-reported physician-confirmed diagnoses and symptom criteria. Methods: We analyzed data obtained from the Tucson Epidemiologic Study of Obstructive Lung Diseases. Using responses to standardized respiratory questionnaires administered to 4,034 subjects, those with NCBRs were selected and assessed as to whether they met symptom criteria for that diagnosis. Descriptive statistics pertaining to gender, age, and smoking status were obtained. Furthermore, we determined how often symptom criteria were met among a subset of subjects with physician-confirmed self-reported diagnoses. Results: Of 481 subjects with NCBRs, only 56 subjects (11.6%) met the required symptom criteria. Men compared with women and current smokers compared with ex-smokers or neversmokers were more likely to meet symptom criteria. Four hundred fifteen of 481 subjects with NCBRs had physician-confirmed self-reported diagnoses. Of these, only 52 subjects (12.5%) met symptom criteria. Within the subgroup of subjects who met symptom criteria, higher percentages were observed in the older age groups, but this was not statistically significant. Conclusion: Only a minority of subjects with NCBRs satisfy the symptom criteria of cough and sputum production for at least 3 months per year for at least 2 consecutive years. This relationship holds true even among those with physician-confirmed self-reported diagnoses. (CHEST 2002; 122:1234 –1239)
Using overlays to support collaborative interaction with display walls

Large-scale display walls, and the high-resolution visualizations they support, promise to become ubiquitous. Natural interaction with them, especially in collaborative environments, is increasingly important and yet remains an on-going challenge. Part of the problem is a resolution mismatch between low-resolution input devices and high-resolution display walls. In addition, enabling concurrent use by multiple users is difficult - for example, how would this large workspace be managed for multiple users and what novel collaborative interactions could occur? In this paper, we present an overlay interface element superimposed on wall-display applications to help constrain interaction, focus attention on subsections of a display wall, and facilitate a collaborative multi-user workflow.
Effect of dilution on the spin pairing transition in rhombohedral carbonates

The compressibility of an iron-bearing magnesite (Mg_(0.87)Fe^(2+)_(0.12)Ca_(0.01))CO_3 was determined by means of single crystal diffraction up to 64 GPa. Up to 49 GPa the pressure-evolution of the unit cell volume of the solid solution with 12% of Fe^(2+) can be described by a third-order Birch-Murnaghan equation of state with parameters V_0 = 281.0(5)A^3, K_0 = 102.8(3) GPa, K'_0 = 5.44. The spin pairing of the Fe^(2+) d-electrons occurs between 49 and 52 GPa, as evidenced by a discontinuous volume change. The transition pressure is increased by about 5 GPa compared with the iron end-member; an effect consistent with a cooperative contribution of adjacent clusters to the spin transition. The trend is, however, opposite in the periclase-wstite solid solution. Differences among the two structures, in particular in the Fe-Fe interactions, that might explain the different behavior are discussed.
High Speed Heterojunction JFETs Grown by Non-Hydride MOCVD

Indium Phosphide channel JFET's with InGaAs lattice matched gate have been fabricated using liquid, non-hydride column V precursors. The incorporation of low bandgap InGaAs gate layer not only suppresses hole injection under forward bias but also makes fabrication of HJFETs very reproducible and easy. Self-aligned devices made by selective etching of the gate resulted in devices with current gain cut-off frequency as high as 22 GHz with transconductance over 200 mS/mm for gate length of about 0.65 µm.
Functional morphology as an aid in determining trophic behaviour

The arthropod communities of phytotelmata (plant-held waters) are considered excellent subjects for studying and testing community theory. Food webs constructed for phytotelm communities, however, usually exclude mites or determine their placement based on little, if any, actual knowledge of their trophic behaviour. Although individually small, many acarine species attain high population levels and therefore may be important as prey for other inhabitants, as processing chain species in commensal relationships and as competitors of the larger tree hole inhabitants. An understanding of the trophic relationships of acarine inhabitants is therefore essential to an understanding of the dynamics of phytotelm communities. Studies emphasizing the functional morphology of mouth-parts of astigmatic species inhabiting water-filled tree holes in the eastern USA and in Queensland, Australia, reveal a diversity of trophic groups. Among these are ‘shredders’ who ingest leaf material and associated microbes by biting off chunks of leaves, ‘scrapers’ (= grazers) who crop fungal hyphae and/or other microbes and detritus from the substrate surface, and ‘collectors’ who filter microbes and fine particulate matter from the water. This information allows for the more exact placement of acarine inhabitants in food webs of water-filled tree holes.
Gastrointestinal hemodynamics during compensation for hemorrhage and measurement of Pmcf.

To quantify the degree of autonomic reflex control of the gastrointestinal vasculature, we studied the responses to a 10-ml/kg hemorrhage or transfusion and autonomic blockade in fentanyl- and pent...
REYE'S SYNDROME

The most important recent development in our understanding of Reye's syndrome is the epidemiologic evidence linking this disease to aspirin in the United States. Assessment of epidemiologic issues of concern raised in prior studies did not explain the extremely high odds ratios observed in more recent studies. The observation of a dose-response relation between risk of Reye's syndrome and dose of aspirin ingested during the antecedent illness provides further supportive evidence for a causal link between Reye's syndrome and aspirin. Additional evidence for this association in the United States is provided by a marked decline in the use of aspirin among children in the United States, which has been accompanied by a dramatic decline in the incidence of Reye's syndrome. In contrast to experience in the United States, Reye's syndrome affecting primarily children aged 5-15 years has been relatively rare in Great Britain and Australia where acetaminophen rather than aspirin is the primary analgesic/antipyretic used. With the declining incidence of aspirin use in the United States, Reye's syndrome among children aged 5-15 years is becoming increasingly rare in the United States as well and, as in Great Britain and Australia, an increasing proportion of cases are being reported in children aged less than five years. Recent reports have suggested that many children younger than age five years who are thought to have the disease may be shown to have other metabolic disorders.(ABSTRACT TRUNCATED AT 250 WORDS)
Micro-potentiometric pH determinations of muscoid maggot digestive tracts.

Gut p Hs of conventional and gnotobiotic maggots of Musca domestica L., Phormia regina (Meigen), Sarcophaga bullata Parker, and Calliphora vicina Robineau- Desvoidy were obtained by micro-electrode. Crop p H is unbuffered and fluctuates with p H of the food which is influenced by microbial activity. However, the 3 regions midgut appear buffered, and their p H is microbe-independent. The fore-midgut is slightly basic in C. vicina, and neutral or slightly acid in the other species. The mid-midgut is most strongly acid in C. vicina, with 2.8 the lowest p H recorded. In order of decreasing acidity are S. bullata, M. domestica, and P. regina. The hindmidgut hovers near neutrality.
Hydrogen Production from Methanol over Gold Supported on ZnO and CeO2 Nanoshapes

In the present study we have found that gold supported on CeO2 and ZnO with well-defined crystal structures or shapes is an excellent catalyst for the low-temperature (175−225 °C) steam reforming of methanol (SRM). We have compared the active nature of gold dispersed on {0001} surfaces of ZnO nanorods and polyhedra to our previous work, which demonstrates that TEM-invisible gold dispersed on the {110} surfaces of CeO2 catalyzes the SRM reaction in a cooperative mechanism with CeO2. Similar to Au−CeO2, we have found that Au−O bonds are essential species for SRM over Au−ZnO and the same apparent activation energy (110−120 kJ·mol−1) of the reaction was calculated for both catalysts. On the basis of temperature-programmed surface reaction/mass spectrometry analysis, we determined that the SRM reaction on both Au−ZnO and Au−CeO2 involves methanol dehydrogenation, methyl formate hydrolysis, and formic acid decomposition steps to produce CO2 and H2. Better than 95% catalyst selectivity to CO2 was found over the ...
Controlled growth of filamentous fatty acid vesicles under flow.

The earliest forms of cellular life would have required a membrane compartment capable of growth and division. Fatty acid vesicles are an attractive model of protocell membranes, as they can grow into filamentous vesicles that readily divide while retaining their contents. In order to study vesicle growth, we have developed a method for immobilizing multilamellar fatty acid vesicles on modified glass surfaces and inducing filamentous membrane growth under flow. Filament formation strictly depended on the presence of freshly neutralized fatty acid micelles in the flow chamber. Using light microscopy, we observed a strong dependence of initial growth velocity on initial vesicle size, suggesting that new fatty acid molecules were incorporated into the membrane over the entire external surface of the vesicle. We examined the influences of flow rate, fatty acid concentration, and salt concentration on filamentous growth and observed drastic shape changes, including membrane pearling, of preexisting membrane tu...
Generation Differences in Korean Immigrants' Life Conditions in the United States:

Generation differences between Korean immigrant adult children and elderly parents are examined in terms of their life conditions in the United States. Data for this study were collected through in...
Structure of Turbulence in Channel Flow with a Fully Transpired Wall

The structure of turbulence in a channel flow with a fully transpired wall has been investigated experimentally. 2D Particle Image Velocimetry is used to measure the instantaneous flow fields within the channel for three different porous surfaces: 1/4" honeycomb, foam (used as the direct porous interface and attached to a 1/4" honeycomb) and 1/8" honeycomb. Mean flow properties and statistics are obtained by analyzing the instantaneous measurements. Comparison with analytical and computational results is made. It is found that the boundary conditions on the porous surface are very important to the internal core flow evolution and flow pattern. For a coarse porous surface (in this paper, 1/4" honeycomb), the mean flow differs significantly from the classical laminar solution and computational results, and much more turbulent shear stress is indicated. However, with small pore size (in this paper, 1/8" honeycomb), the mean velocity profiles are very close to the laminar solution for a considerable downstream length, even though large turbulence intensity (5%) is observed. Therefore, profound modification of the flow structure can occur due to the effect of non-ideal wall boundary conditions on the porous surface. In addition, the location where the maximum RMS turbulence intensity occurs moves closer to the porous surface with increasing downstream position.
Analysis on monitoring results of preservative in market food in Mianyang City

[Objective]To understand whether there exists the over range utilization and overdose of preservative in market food in Mianyang City.[Methods]Food samples were collected or purchased from supermarkets,farm product markets and retail stores near school in Mianyang urban area,Anxian County,Santai County and Jiangyou City,and were detected by chromatography method.[Results]A total of 184 food samples were detected,175 samples were qualified,and the qualification rate was 95.11%.6 samples were unqualified,with the unqualified rate of 4.89%.The benzoic acid was detected in 66 samples with the detection rate of 35.87%,while the sorbic acid was detected in 61 samples with the detection rate of 33.15%.[Conclusion]The detection rate of benzoic acid and sorbic acid in market food is high in Mianyang City,but there are not clear instructions in food labels.The relevant departments should take pertinent measures and strengthen the supervision,as so to ensure that the consumer's right to know the truth and their health.
History of Community Health Services Informatization Construction in China as Well as Data Sharing Mode

The paper elaborates the development history of community health services and health informatization in China,points out the characteristics,analyzes the complexity,different models,affect factors and applications of data sharing on community health information system,so as to provide references for the informatization construction on community health services.
Expression of MICA,MMP-9 and NF-κB and their correlation in osteosarcoma

Purpose To investigate the mechanism of the expression and shedding of MHC class Ⅰ chain-related A(MICA),and the relationship between MICA,MMP-9 and NF-κB expression in osteosarcoma.Methods MICA expression was examined in 66 cases of osteosarcoma,11 osteoblastoma,8 ossifying fibroma and 6 normal bone tissues by immunohistochemistry,in which the expression of MMP-9 and NF-κB were also evaluated in the osteosarcoma cases.Results(1) The expression rates of MICA protein in osteosarcoma,osteoblastoma,ossifying fibroma and normal bone tissues were 51.6%(34/66),9%(1/11),0(0/8) and 0(0/6),respectively.Up-regulation of MICA expression was found in osteosarcoma,compared with osteoblastoma(P=0.01),ossifying fibroma(P0.01) and normal bone tissues(P0.05).(2) MMP-9 and NF-κB were detected in 55%(36/66) and 73%(48/66) of osteosarcoma,respectively.NF-κB expression increased with elevated expression of MICA(r=0.373,P0.01) and MMP-9(r=0.536,P0.01).Conclusions MICA protein is a useful molecular marker for the diagnosis of osteosarcoma;NF-κB may play a role in the molecular mechanism of the expression and shedding of MICA protein in the osteosarcoma,and it may be a putative target for immunotherapy in osteosarcoma.
Distinction in EEG slow oscillations between chronic mild traumatic brain injury and PTSD

Spectral information from resting state EEG is altered in acute mild traumatic brain injury (mTBI) and in disorders of consciousness, but there is disagreement about whether mTBI can elicit long term changes in the spectral profile. Even when identified, any long-term changes attributed to TBI can be confounded by psychiatric comorbidities such as PTSD, particularly for combat-related mTBI where postdeployment distress is commonplace. To address this question, we measured spectral power during the resting state in a large sample of service members and Veterans varying in mTBI history and active PTSD diagnosis but matched for having had combat blast exposure. We found that PTSD was associated with decreases in low frequency power, especially in the right temporoparietal region, while conversely, blast-related mTBI was associated with increases in low frequency power, especially in prefrontal and right temporal areas. Results support the idea that long-term neurophysiological effects of mTBI share some features with states of reduced arousal and cognitive dysfunction, suggesting a role for EEG in tracking the trajectory of recovery and persisting vulnerabilities to injury. Additionally, results suggest that EEG power reflects distinct pathophysiologies for current PTSD and chronic mTBI.
Studies in experimental eosinophilia. II. Induction of peritoneal eosinophilia by the transfer of tissues and tissue extracts.

Tissues taken from one guinea pig were transferred into the peritoneal cavity of another, and the total number of peritoneal eosinophils in the recipient was determined 24 hours after transfer. Peritoneal eosinophilia resulted in the recipients when peritoneal lining, lungs, blood or serum were taken from an animal previously prepared by repeated injections of foreign protein and transferred along with some of the same protein. With lung, but not with peritoneal lining, some eosinophil responses were noted when the protein used to prepare the donor was omitted, and when either the donor or recipient was a normal animal. Extracts of peritoneal lining or lung also induced peritoneal eosinophilia. Isolated instances of activity occurred in extracts of normal tissues, but most of the positive responses were induced when extracts from animals previously prepared with foreign protein were accompanied by the same protein. Eosinophilotactic activity remained inside dialysis bags. It was stable to 56 C. for ½ hour, 4 C. for 24 hours, and -5 C. for two days. The activity disappeared with the removal of trichloracetic acid-precipitable material. These experiments support the view that eosinophilia may occur in the absence of actively acquired antibody, and that an eosinophilotactic mechanism may be passively transferred from one guinea pig to another.
Body weight, tick burden (Boophilus microplus), physiological parameters and reproductive efficiency of crossbred zebu cattle.

Body weight at calving, degree of tick load (Boophilus microplus), rectal temperature, respiratory frequency and heart rate were evaluated and correlated to reproductive efficiency in 63 F1 Brown Swiss x Nellore milked animals reared in the tropical region of Peru. Cows were bred by free natural service, and first ovulation was estimated by progesterone measurements. The physiological parameters were registered at morning milking (04.00 to 06.00) at an average air temperature of 22.4±0.9°C. The intervals from parturition to first ovulation and conception were significantly affected when the body weight at calving was lower than 400 kg (p < 0.01). The degree of tick burden, rectal temperature (38.4±0.2°C, $$\bar x$$ ± s.e.), respiratory rate (25.2±0.3 breaths/min) and heart; rate (66.7±0.4 beats/min) were not related to post-partum reproductive efficiency. The average intervals from parturition to first ovulation and to conception were 56.3±55.5 and 77.7±46.0 days $$\bar x$$ ± s.d.), respectively. The fertility rate was 85.7%. The results indicate the F1 cross to be well adapted to the given environment. It remains to be determined whether higher levels of temperate blood can be used without an accompanying decrease in reproductive performande.
Office of Laboratory Animal Welfare Comments

In support of the new column in Zebrafish dedicated to initiating conversations about animal care policies and compliance for the zebrafish, the Office of Laboratory Animal Welfare (OLAW) has offered the following clarification and guidance.
Clinical implementation of whole genome multi-omics analyses for patients with refractory cancers.

1531Background: Relative lack of prior success of genomic technology has been a function of suboptimal target detection and poor timely implementation. We set out to improve patient access to targeted therapy through use of whole genome sequencing (WGS) to optimize targets and operational implementation to identify clinical trials and secure off-label drugs. Methods: We performed a retrospective analysis of our first 100 patients (Feb-Nov 2016) with metastatic disease whose tumors and matched blood were analyzed using whole genome (WGS) and transcriptome sequencing, as well as targeted proteomic analysis in a CLIA setting (NantOmics). Most common tumor types were Colorectal (20%), Breast (15%), and Ovarian (10%). Patients were seen in dedicated precision genomics clinics with results reviewed by a multi-disciplinary molecular tumor board. A dedicated service line with staff to match patients to clinical trials, medication acquisition, and genetic counseling for germline findings was provided. Results: 85%...
Teaching Neuro Images: Classic Ramsay Hunt syndrome and associated MRI findings

An 85-year-old woman with dementia presented with left ear pain, vertigo, and mild left peripheral facial weakness of unclear chronicity. MRI demonstrated contrast enhancement of cranial nerves (CNs) VII and VIII consistent with Ramsay Hunt syndrome (RHS)1 (figure 1). She was treated with steroids and acyclovir. On evaluation 4 days later, she had developed the classic RHS triad of ear pain, ipsilateral facial paralysis, and vesicular rash, plus hyperacusis and persistent vertigo (figure 2).2
Fanciful Flights: Reimagining Refugee Narratives of Escape in Kao Kalia Yang's The Latehomecomer: A Hmong Family Memoir

The refugee camp has become a mainstay in dealings with displaced persons, offering a modicum of shelter and community, and serving as a processing site for relief agencies. Reflecting both the urg...
Project USAP 2000--use of sedative agents by pediatric dentists: a 15-year follow-up survey.

Purpose A national survey of members of the American Academy of Pediatric Dentistry was conducted to provide a 15-year update of information regarding the use of sedative agents by pediatric dentists. Methods All 3,315 active members of the Academy were sent questionnaires regarding the frequency of their use of sedation and 1,778 responded. Practitioners were questioned regarding their use of sedative agents and the nature of their patients receiving sedation. In addition, they were questioned in regard to their use of restraints and reasons for change in their use of sedation during the past two years. Results In regard to the use of nitrous oxide alone, 47% of practitioners responded that they use nitrous oxide less than 11% of the time. In regard to other types of sedative agents, most practitioners use little, if any, sedation. Eighty-two percent use sedation for less than 11% of their patients. Of the 1,778 respondents, 1,224 used drugs other than nitrous oxide. In a typical three-month period, they performed 77,112 sedations. Of that number, 61,662 (80%) were administered by only 478 practitioners who use sedation on the average of once or greater each day. Conclusions In comparison with previous surveys in 1985, 1991 and 1995, these results demonstrate an overall increased use of sedation by pediatric dentists. However, the increased use is due primarily to an increase in the numbers of practitioners who are heavier users of sedation (once or greater each day).
Sand Particle Breakage under High-Pressure and High-Rate Loading

Under intensive loading, either hydrostatic or dynamic shear, sand particles are broke up to smaller particles. In this study, we randomly embedded color-coated sand grains of five different initial sizes inside cylindrical sand specimens under dynamic tri-axial loading. The quasi-static pressure was varied from 25 to 150 MPa at 25 MPa intervals and then unloaded. The embedded particles were retrieved and found fractured particles increased with increasing pressure. However, many of the colored particles remained intact. Under 100-MPa hydrostatic pressure, additional axial load was added at three different strain rates, 0.01, 500, and 1000 s-1. It was found that, under additional dynamic loading nearly all the colored particles were fractured. In addition, to the attention on the embedded colored particles, the overall size change of the sand from the loaded specimens were also quantified.
Cyclodextrin Rotaxane with Switchable Pirouetting

A [1]rotaxane with two threaded α-cyclodextrin (α-CD) wheels was synthesized in 92% yield using a one-pot process at room temperature that employed spontaneous α-CD threading onto a 12-carbon alkyl chain in water followed by an oxime condensation reaction that attached two boronic acid-containing stopper groups. Rapid pirouetting of the threaded α-CD wheels around the encapsulated dumbbell was switched “ON” or “OFF” by the presence of chemical additives that controlled boronate ester bond formation between the interlocked components.
Bacteremia caused by cellulosimicrobium in a bone marrow transplant patient: A case report and literature review.

Abstract Background Cellulosimicrobium sp. is a ubiquitous gram-positive bacillus that was formerly known as Oerskovia. This bacterium is found in soil and decaying plant material and is rarely associated with infections in humans. Case report We report the case of a 44 year-old woman with history of bone marrow transplant that developed Cellulosimicrobium sp. bacteremia secondary to a central line infection. She was admitted with presumed sepsis. Blood cultures from central line and periphery revealed the growth of gram-positive rods that were further identified as Cellulosimicrobium sp. by MALDI-TOF. She was treated with vancomycin and line removal. Microbiologic cure was achieved; however, she developed hospital-acquired pneumonia, which led to a fatal outcome. Conclusion To our knowledge, there are only 15 documented cases of Cellulosimicrobium sp. bacteremia. Our case illustrates the potential pathogenicity of this bacterium and the importance of appropriate antimicrobial therapy and removal of infected central catheters. It is essential to know that gram-positive bacilli should not be disregarded as contaminants when recovered from multiple blood cultures. In this situation, a full microbiologic identification must be attempted.
House Rules: Designing the Scoring Algorithm for Cyber Grand Challenge

The key driving force behind any capture-the-flag competition is the scoring algorithm; the Cyber Grand Challenge (CGC) was no different. The scoring algorithm design for both the CGC Qualifier Event (CQE) and the CGC Final Event (CFE) focused heavily on encouraging development of automated reasoning about software and its inputs, discouraging collusion and cheating, and representing real-world constraints to ensure resulting solutions developed by CGC competitors were well-positioned for adoption outside the Cyber Grand Challenge competition. In this article, we describe design considerations for CQE and CFE scoring algorithms, how these algorithms intended to incentivize competitors to achieve these goals, and effects these decisions had on the resulting gameplay in CGC.
The Effect of Shift Work on Urogenital Disease: a Systematic Review

Non-standard shift work schedules negatively impact the overall health of shift workers, and several studies have shown that shift work, specifically, is detrimental to urogenital health. The aims of this study are to systematically review the literature and determine the effect of shift work on the outcomes of hypogonadism, male infertility, lower urinary tract symptoms, and urogenital cancers. Recent evidence supports associations between non-standard shift work and an increase in the frequency of prostate cancer and the severity of erectile dysfunction, lower urinary tract symptoms, and hypogonadal symptoms, as well as worsening of semen parameters and fertility. These associations are strengthened by the presence of shift work sleep disorder (SWSD) which affects up to 20% of shift workers. No studies have assessed the impact of shift work on the frequency or severity of nephrolithiasis, interstitial cystitis, pelvic pain, prostatitis, or urinary tract infections. Non-standard shift work has been associated with a variety of negative health outcomes and urologic complications, especially with concurrent shift work sleep disorder. Recognition of these elevated risks among shift workers can aid in more effective screening for urologic conditions.
The Experimental Study of Behaviorally Induced Arrhythmias

The belief that psychological stress can precipitate major illness has long been accepted in both folk wisdom and medical thinking, but its scientific basis is fragmentary and incomplete.
Ultrasonic Signal Attenuation in Engine Titanium Alloys

The titanium alloys used in rotating jet engine components present interesting UT inspection challenges. They have complicated, duplex, anisotropic structures which vary on several dimensional scales [1,2]. Individual metal crystallites with typical dimensions on the order of several microns comprise the fine scale structure (microstructure). Colonies of aligned crystallites, which develop from prior beta grains during cooling, can have dimensions of several millimeters and comprise the large scale structure (macrostructure). Cylindrical billets destined for use in rotating engine components are typically inspected using 5 MHz broadband transducers, with higher frequency inspections planned. Because macrostructure dimensions often exceed the sonic wavelength, sound beams can be distorted during propagation, leading to modifications of ultrasonic signals. These modifications are of two basic types: (1) identical reflectors at the same depth but located at different sites on a specimen produce different sonic echoes due to the influence of the local macrostructure (signal fluctuation); and (2) the average signal strength is different from the value it would have in a similar fine-grained material (signal attenuation).
Dental adhesives: a perspective.

Abstract : A study based on the laboratory characterization of four adhesive restoratives was conducted. The findings indicated that adhesion of three of the materials to the components of tooth structure was unreliable. Strength properties of adhesive systems of the BIS-GMA type were superior to those of a glass ionomer cement. Clinical application of the test materials should be limited to the restoration of conventional Class III and Class V cavities.
Sociolinguistic Capital and Fresa Identity Formations on the U.S.-Mexico Border

This study analyzes sociolinguistic styles among Mexican women in the northern border cities of Juarez, Chihuahua and El Paso, Texas. These speakers’ grafting of sociolinguistic elements that resemble particular U.S. English styles ref lects what are understood in Mexico as fresa stereotypes. These linguistic innovations signal emblems of social prestige under the increasingly extensive influences of the neoliberal political economy. Through an examination of bilingual speech patterns in Spanish and in English, along with consideration of other sociolinguistic practices, I document how U.S.-centered ideologies of upper-class white feminine consumer culture are absorbed and rearticulated by women in the U.S.-Mexico border region.
Abstract P281: Psychosocial Factors Are Strongly Associated With Sleep Disturbances and Evening Chronotype Among Diverse Women: Evidence From the AHA Go Red for Women Strategically Focused Research Network

Background: Psychosocial factors have been linked to increased CVD risk through biological and behavioral mechanisms, possibly including short and/or long sleep duration. However, relations between...
Teaching Secondary School Students with Learning Disabilities to Cope in Preparation for College.

The purpose of this article is to explore how to teach secondary school students with learning disabilities (LD) to cope effectively, so they may develop self-determination (independence) skills in...
Multitask Learning for Network Traffic Classification

Traffic classification has various applications in today’s Internet, from resource allocation, billing and QoS purposes in ISPs to firewall and malware detection in clients. Classical machine learning algorithms and deep learning models have been widely used to solve the traffic classification task. However, training such models requires a large amount of labeled data. Labeling data is often the most difficult and time-consuming process in building a classifier. To solve this challenge, we reformulate the traffic classification into a multi-task learning framework where bandwidth requirement and duration of a flow are predicted along with the traffic class. The motivation of this approach is twofold: First, the bandwidth requirement and duration are useful in many applications, including routing, resource allocation, and QoS provisioning. Second, these two values can be obtained from each flow easily without the need for human labeling or capturing flows in a controlled and isolated environment. We show that with a large amount of easily obtainable data samples for bandwidth and duration prediction tasks, and only a few data samples for the traffic classification task, one can achieve high accuracy. Therefore, our proposed multi-task learning framework obviates the need for a large labeled traffic dataset. We conduct two experiments with ISCX and QUIC public datasets and show the efficacy of our approach.
Metabarcoding quantifies differences in accumulation of ballast water borne biodiversity among three port systems in the United States.

Abstract Characterizing biodiversity conveyed in ships' ballast water (BW), a global driver of biological invasions, is critically important for understanding risks posed by this key vector and establishing baselines to evaluate changes associated with BW management. Here we employ high throughput sequence (HTS) metabarcoding of the 18S small subunit rRNA to test for and quantify differences in the accumulation of BW-borne biodiversity among three distinct recipient port systems in the United States. These systems were located on three different coasts (Pacific, Gulf, and Atlantic) and chosen to reflect distinct trade patterns and source port biogeography. Extensive sampling of BW tanks (n = 116) allowed detailed exploration of molecular diversity accumulation. Our results indicate that saturation of introduced zooplankton diversity may be achieved quickly, with fewer than 25 tanks needed to achieve 95% of the total extrapolated diversity, if source biogeography is relatively limited. However, as predicted, port systems with much broader source geographies require more extensive sampling to estimate diversity, which continues to accumulate after sampling >100 discharges. The ability to identify BW sources using molecular indicators was also found to depend on the breadth of source biogeography and the extent to which sources had been sampled. These findings have implications both for the effort required to fully understand introduced diversity and for projecting risks associated with future changes to maritime traffic that may increase source biogeography for many recipient ports. Our data also suggest that molecular diversity may not decline significantly with BW age, indicating either that some organisms survive longer than recognized in previous studies or that nucleic acids from dead organisms persist in BW tanks. We present evidence for detection of potentially invasive species in arriving BW but discuss important caveats that preclude strong inferences regarding the presence of living representatives of these species in BW tanks.
The Wyoming Survey for Hα. II. Hα Luminosity Functions at z 0.16, 0.24, 0.32, and 0.40

The Wyoming Survey for Hα, or WySH, is a large-area, ground-based imaging survey for Hα-emitting galaxies at redshifts of z 0.16, 0.24, 0.32, and 0.40. The survey spans up to 4 deg2 in a set of fields of low Galactic cirrus emission, using twin narrowband filters at each epoch for improved stellar continuum subtraction. Hα luminosity functions are presented for each Δz 0.02 epoch based on a total of nearly 1200 galaxies. These data clearly show an evolution with look-back time in the volume-averaged cosmic star formation rate. Integrals of Schechter fits to the incompleteness- and extinction-corrected Hα luminosity functions indicate star formation rates per comoving volume of 0.010, 0.013, 0.020, 0.022 h 70 M ☉ yr–1 Mpc–3 at z ~ 0.16, 0.24, 0.32, and 0.40, respectively. Combined statistical and systematic measurement uncertainties are on the order of 25%, while the effects of cosmic variance are at the 20% level. The bulk of this evolution is driven by changes in the characteristic luminosity L * of the Hα luminosity functions, with L * for the earlier two epochs being a factor of 2 larger than L * at the latter two epochs; it is more difficult with this data set to decipher systematic evolutionary differences in the luminosity function amplitude and faint-end slope. Coupling these results with a comprehensive compilation of results from the literature on emission line surveys, the evolution in the cosmic star formation rate density over 0 z 1.5 is measured to be .