cssi/SciSciGPT-SciSciNet huggingface dataset:
An Elderly Patient With Palpitation and a Negative Nuclear Stress Test Result.

Aman in his 80swas hospitalized with recurrent syncope. He denied chest pain.Onadmission, hewashemodynamically stable and physical examinationhadnormal results.Electrocardiography (ECG) showedsinus rhythm, right bundlebranchblock, andT-wave inversion in inferior and V3 through V6 leads (Figure 1). His serial troponin levels were negative for abnormalities. Because of baseline abnormal ECG results and low ejection fraction, he underwent regadenoson vasodilator stress myocardial perfusion imaging (MPI) to ruleout ischemic cardiomyopathy. Therewasno ischemia andno left ventricle cavitydilationduring stress imaging.However, justbefore discharge, he developed palpitations with mild chest discomfort. The patient’s ECG during palpitation is shown in Figure 2. He wassymptomaticwithnormalbloodpressure, sohewastreatedwith an intravenous β-blocker. Following that, his symptoms resolved (Figure 3). Questions:What is the most appropriate next step in evaluation andmanagement?His nuclear stress test during the indexhospitalization was negative for ischemia; does he still need coronary angiography?
Mechanoreception in calanoid copepods

A model of early detection of individual algal prey by copepod mechanoreception suggests that mechanoreception may serve as an indicator of prey position. Our model shows that the magnitude of the pressure disturbance created by a particle entrained in a feeding flow of a copepod increases linearly with increasing particle size, decreases as the square of the distance away from the antenna, and is unique for a given particle size. These pressure disturbances may be utilized by the copepod to determine the size and location of particles present in the feeding current and may provide information necessary for initial prey detection.
Comparative Toxicity of Some Molt-Inhibiting Insecticides to the Gypsy Moth

The 3rd and 5th larval instars of gypsy moth, Lymantria dispar (L.), were fed on treated diet contailling various concentrations (0.0 to 0.8 ppm) of molt-inhibiting insecticides, L-7063 (N-[[[5-(4-bromophenyl-6-methyl-2-pyrazinyl]animo]-carbonyl]-2-chlorobenzamide), L-1215 (2,6-dimethoxy-N-[5-[4-(pentafluoroethoxy)-phenyl]-1,3,4-thiadiazole-2-yl]benzamide), and diflubenzuron, and the larvae were scored for molting abnormalities. EC50 values for L-7063, L-1215, and diflubenzuron for failire of the 3rd instar to molt to the 4th instar were 0.176, 0.513, and 0.052 ppm, and for failure to molt the second time (to the 5th instar) were 0.075, 0.175, and 0.009 ppm, respectively. EC50 values for failure of the 5th instar to molt to pupae (♂) or to the 6th instar (♀) were 0.094, 0.531, and O.122 ppm, respectively. Continuous feeding of 3rd instars until pupal formation on diet containing L-7063 or diflubenzuron resulted in lower EC50 values of 0.009 and 0.006 ppm, respectively. Diflubenzuron was more toxic to the 3rd instar, but L-7063 was most toxic to the 5th instar. The slopes of the probit regression lines varied between compounds and instar treated which implies variation in mechanism of action or chemical or physical processes.
The First Attempt at a Table of Integrals

(1922). The First Attempt at a Table of Integrals. The American Mathematical Monthly: Vol. 29, No. 10, pp. 392-394.
Vortex and meteorological measurements at Dallas/Ft. Worth airport

As part of NASA’s Aircraft Vortex Spacing System (AVOSS), Lincoln Laboratory conducted meteorological and wake vortex data collections at Dallas/Ft. Worth (DFW) airport in 1997. A mobile continuous-wave coherent CO2 laser radar was utilized to detect and track vortices generated by landing aircraft. Associated meteorological data were acquired by an extensive array of weather sensors. The DFW deployment is described here along with a preliminary analysis of vortex data. Vortex measurements from a 1995 lidar deployment in Memphis are also included in the analysis.
Ultrastructure of teliospore ontogeny in Tilletia indica

Teliospores of Tilletia indica, the Karnal bunt fungus of wheat, arose from a fixed hymenium lining all surfaces of a cavity formed by separation of the inner and outer layers of the pericarp of the grain. Scanning and transmission electron microscopy showed that the spore originated as a swelling cut off at the tip of a sporogenous hypha by a septum. The wall of the parent sporogenous cell formed the primary wall of the spore initial. Centripetal deposition of secondary wall material against the primary wall produced: 1) a thin, uniform outer layer that fused with the primary wall to form a sheath; 2) an electron opaque exospore ornamented with spines; 3) a uniform, granular endospore; and 4) a thin partition layer of sinuous lamellae separating the exospore and endospore. The complex exospore was composed of a series of concentric fibrous bands divided into two layers. In the outer ornamented layer localized deposits of dense amorphous material cemented the fibrous bands into conical spines separated by interspinal areas of loosely arranged bands. Inside of the ornamented layer the deposits of amorphous material formed a continuous dense basal layer that merged with the broad bases of the spines. The apiculus sometimes present on mature spores represented the shriveled subapical cell of the sporogenous
Discovery of medical Big Data analytics: Improving the prediction of traumatic brain injury survival rates by data mining Patient Informatics Processing Software Hybrid Hadoop Hive

Abstract Entering medical encounter data by hand is time-consuming. In addition, data are often not entered into the database in a timely enough fashion to enable their use for subsequent mission planning. The Patient Informatics Processing Software semi-automates the data collection process onboard ships. Then data within these images are captured and used to populate a database, after which multiple ship databases are used for reporting and analysis. In this paper, we used the Patient Informatics Processing Software Hybrid Hadoop Hive to orchestrate database processing via various ships, by marshaling the distributed servers, running the various tasks in parallel, managing all of the communications and data transfers between the various parts of the system, and providing for redundancy and fault tolerance. Then we employed the Apache Hive as a data warehouse infrastructure built on top of Hadoop for data summarization, query, and analysis to identify traumatic brain injury (TBI) as well as other injury cases. Finally, a proposed Misdiagnosis Minimization Approach method was used for data analysis. We collected data on three ship variables (Byrd, Boxer, Kearsage) and injuries to four body regions (head, torso, extremities, and abrasions) to determine how the set of collected variables relates to the body injuries. Two dimensions or canonical variables (survival vs. mortality) were necessary to understand the association between the two sets of variables. Our method improved data classification and showed that survival, mortality, and morbidity rates can be derived from the superset of Medical Operations data and used for future decision-making and planning. We suggest that an awareness of procedural errors as well as methods to reduce misclassification should be incorporated into all TBI clinical trials.
Quality Surveillance of Drinking Water in Nan-an District During 2004 to 2009

Objective To know about the quality of drinking water in Nan-an District and to provide suggestions for improving it.Methods 4131 Samples of drinking water were selected to evaluate the quality of water by using the national standard from 2004 to 2009.Results The qualified rates of urban secondary water,supply tap water,chlorinated water,and source water were 96.28%、88.16%、73.49%and 9.55%.In five indexes of supply tap water,the free residual chlorine `qualified rate was the highest,and moreover,the index of coli group was the lowest.The eligible indexes of Secondary water were visible residue,free residual chlorine and ph.Conclusions The quality of Secondary water and supply tap water were higher than others.Chlorinated water should be more cleared.We should enhance consciousness of environmental protection to protect environment.The relevant departments should pay special attention to the existed problems of source water.
The Present Status and Future Path of Creative Agritourism in Yunnan Province

Yunnan is the province that rely on its tourism in China. In these years,Yunnan province de-pends on affluent resource and unique geography into creative agritourism with developed conception,whichgains a series of achievements. creative agritourism is a emerging cross industry which combines tourism withagriculture,it takes advantage of creative conception to change agricultural resources so that this industry cre-ate new customer. present creative agritourism in Yunnan need to break though the constraints and find out newchannel which can develop. this article analyze the bottleneck of creative agritourism in Yunnan,and givesome worthy opinion and conception,trying to give the conclusion and exploration for development about cre-ative agritourism.
Escharotic Treatment for ECC-positive CIN3 in Childbearing Years: A Case Report.

A persistent human papillomavirus (HPV) infection of a high-risk type is necessary for cervical cancer to develop. The severity of the diagnosis, together with colposcopy findings, determines the standard for treatment, and ablative or excisional options may be recommended. Escharotic treatment, together with an oral, anticarcinogenic HPV protocol and a vaginalsuppository protocol, is an alternative treatment, especially for those women of childbearing age who are concerned about the possibility of obstetrical complications associated with the use of loop electrosurgical excision (LEEP). The aim of the current case study was to observe the effect of an ablative escharotic treatment for a woman with severe dysplasia, cervical intraepithelial neoplasia grade 3 (CIN3). A 28-y-old female visited the National College of Natural Medicine clinic to obtain suggestions for alternative treatments following a satisfactory colposcopy and a biopsy revealing a high-risk HPV effect, severe dysplasia CIN3, and a positive endocervical curettage (ECC). She refused the recommended standard of care, a LEEP, because of concerns about the potential for future obstetrical complications. As an alternative, she elected to receive an escharotic treatment at a frequency of 2 treatments/wk for 5 wk. In addition to the escharotic treatment, she followed an oral protocol consisting of vitamins and botanical medicine for 1 y and she completed a 12-wk regime of vaginal suppositories following the escharotic. The authors followed her for 2 y. The woman’s Papanicolaou (Pap) test at the 6-mo follow-up revealed negative cervical cytology for intraepithelial lesion or malignancy, and her follow-up ECC was negative. Liquid-based Pap results were normal, and HPV testing was negative at her 1-y followup. Her Pap continued to remain normal at her 2-y follow-up. For women with high-grade cervical neoplasias and positive ECCs, with satisfactory colposcopies, escharotic treatment, accompanied by oral supplementation, holds promise as an effective alternative to LEEP and other excisional procedures.
Transqueer Representations: Educating Against the Binaries

As we have seen in the previous chapters, there is much to be concerned about regarding the representations of LGBT identities in the digital spaces that we embody. Without careful and critical analysis of the digital representations and spaces that we visit, we consume and learn dangerous and limiting ideas about what it means to be LGBT. In the absence of rigorous interrogation of what we see/read/consume, binaries of sex/gender/sexuality are reinforced instead of questioned and queered. It is imperative that teachers at all levels of the educational system and across various disciplines begin to teach toward critical awareness of consumption, specifically when it relates to LGBT representations. Without learning to look carefully and analytically at what we are consuming on our screens, we run the risk of believing, embodying, and living stereotypes that limit our bodies and minds. This chapter is a call to action for teachers, offering suggestions on how to teach queerness in the digital age and paving the way for teaching critical thinking and unlearning stereotypes that currently permeate our understanding of what it means to be LGBT. As educators—whether we are teaching a high school English class, training elementary/high school/university teachers, or teaching a graduate course in sociology or communication, we have a responsibility to teach critical examination of representations, knowing that these representations—consumed through media and digital texts—create a reality that can be damaging.
Governing equations of transient soil water flow and soil water flux in multi-dimensional fractional anisotropic media and fractional time

Abstract. In this study dimensionally consistent governing equations of continuity and motion for transient soil water flow and soil water flux in fractional time and in fractional multiple space dimensions in anisotropic media are developed. Due to the anisotropy in the hydraulic conductivities of natural soils, the soil medium within which the soil water flow occurs is essentially anisotropic. Accordingly, in this study the fractional dimensions in two horizontal and one vertical directions are considered to be different, resulting in multi-fractional multi-dimensional soil space within which the flow takes place. Toward the development of the fractional governing equations, first a dimensionally consistent continuity equation for soil water flow in multi-dimensional fractional soil space and fractional time is developed. It is shown that the fractional soil water flow continuity equation approaches the conventional integer form of the continuity equation as the fractional derivative powers approach integer values. For the motion equation of soil water flow, or the equation of water flux within the soil matrix in multi-dimensional fractional soil space and fractional time, a dimensionally consistent equation is also developed. Again, it is shown that this fractional water flux equation approaches the conventional Darcy equation as the fractional derivative powers approach integer values. From the combination of the fractional continuity and motion equations, the governing equation of transient soil water flow in multi-dimensional fractional soil space and fractional time is obtained. It is shown that this equation approaches the conventional Richards equation as the fractional derivative powers approach integer values. Then by the introduction of the Brooks–Corey constitutive relationships for soil water into the fractional transient soil water flow equation, an explicit form of the equation is obtained in multi-dimensional fractional soil space and fractional time. The governing fractional equation is then specialized to the case of only vertical soil water flow and of only horizontal soil water flow in fractional time–space. It is shown that the developed governing equations, in their fractional time but integer space forms, show behavior consistent with the previous experimental observations concerning the diffusive behavior of soil water flow.
Omolabus Jekel in north and central America (Coleoptera: Attelabidae)

The genus Omolabus Jekel is redefined and the genus Xestolabus Jekel is assigned to subgeneric status, New Status, under Omolabus. Fourteen species are recognized in the genus Omolabus in North and Central America: O. angulipennis (Sharp) New Combination, O. callosus (Sharp), O. conicollis (Sharp) New Combination, O. corvinus (Gyllenhal) New Combination, O. fasciventris New Species, O. heterocerus (Sharp) New Combination, O. laesicollis (Gyllenhal) New Combi- nation, O. ligulatus (Sharp), O. longiclava (Sharp) New Combination, O. megalomus New Spe- cies, O. quadratus (Sharp), O. sedatus (Sharp) New Combination, O. spinipectus New Species and O. veracruensis New Species. The following species are placed in New Synonymy: X. constrictipennis (Chittenden), X. tabascoensis Voss, O. brevicollis Sharp and O. biimpressus Voss. Lecto- types are designated for the following Sharp species: O. callosus, O. conicollis, O. heterocerus, O. ligulatus, O. quadratus, and O. sedatus. Identification keys based on external characteristics are provided for the New World genus group Attelabina and for all known Omolabus species occurring in North and Central America. Digital habitus images, illustrations of male genitalia and host plant associations are also included.
The quest for the Northern Lights

The Northern Lights is a well researched biographical tale of the Norwegian physicist and genius Kristian Birkeland, whose life was spent exclusively in pursuit of the scientific goal of understanding solar–terrestrial relationships. The author, Lucy Jago, has turned his life into a highly compelling story that keeps the reader interested, and also learning, as the tale unfolds.
Structure-Activity Correlations for the Ferric Uptake Regulation (FUR) Repressor Protein of Escherichia Coli K12

The purpose of this chapter will be to give an overview of certain features of microbial iron metabolism and to record what is known at the moment of writing regarding the molecular mechanism of regulation of high affinity iron absorption in Escherichia coli K-12. Evidence obtained by chemical modification experiments suggests that thiol groups may play a role in the activity of a protein (Fur) regulating iron absorption in this bacterial species.
Wave-theoretical description of the solar gravitational lens

We discuss the propagation of electromagnetic (EM) waves in the post-Newtonian approximation of the general theory of relativity. We consider diffraction of EM waves in the static gravitational field of a massive monopole. We develop a wave-theoretical description of the solar gravitational lens (SGL) and show that with its enormous magnifying power of $\ensuremath{\sim}{10}^{11}$ (for $\ensuremath{\lambda}=1\text{ }\text{ }\ensuremath{\mu}\mathrm{m}$) and angular resolution of $\ensuremath{\lesssim}{10}^{\ensuremath{-}10}\text{ }\text{ }\mathrm{arcsec}$, the SGL may be used for direct megapixel imaging of an exoplanet.
Diet Niche Width and Individual Specialization of Brook Trout in Adirondack Lakes

AbstractWe evaluated diet niche width, individual diet specialization, and diet composition in six lake populations of Brook Trout Salvelinus fontinalis, a generalist predator known to exhibit benthic and pelagic trophic specialization. Population diet niche width was broad and similar across all lakes, contrasting with that of individual fish, which exhibited specialized diets in comparison with their population and other individuals. Overall, the degree of individual diet specialization was high compared with that of other fishes. The degree of individual diet specialization did not differ among study populations, although it was generally reduced in spring. Individual diet specialization was consistent across fish sizes despite observed shifts in diet composition with increasing fish length. Population diet composition varied among lakes but was consistent within lakes in all years during the 3-year study period with regard to season and fish size. The consistency and stability in measures of populatio...
On the Frontlines of the Welfare State: How the Fire Service and Police Shape Social Problems

Although public safety agencies protect our well-being, they also shape social problems and community inequities. Public safety protections promote what T.H. Marshall called "social rights" of equitable citizenship. Frontlines of Welfare State shows how public safety agencies function as welfare state agencies, responsible for a range of essential public functions including emergency service, criminal investigation, regulatory oversight and social service outreach. Furthermore, this volume shows how public safety agencies are being asked to absorb more social welfare functions amidst cut-backs in other areas of the welfare state. Two areas of public safety are examined: arson control and fire prevention, especially within the contexts of urban change and gentrification, and community policing, especially as a mechanism of expanding drug treatment service and prevention programs. Facilitating a greater understanding of institutional biases within the state built around organizational structures, procedures and cultures and their impact on social outcomes, this original and exciting book will be of interest to researchers, practitioners and undergraduate and postgraduate students in the fields of Policing and Fire Control, Public Policy and Administration, Drugs and Substance Abuse and White Collar Crime.
The Optimum Diet of Spray-Dried Animal Blood Cells as Protein Source for Adult Screwworms (Diptera: Calliphoridae)

Spray-dried animal blood cells were evaluated as a protein source for mass rearing adult screwworms, Cochliomyia hominiorax Coquerel. Males and females were fed control diets of either a corn syrup...
The Influence of Freud's Hermeneutic of Suspicion on the Writings of Juan Segundo:

In 1970, Paul Ricoeur published his book, Freud and Philosophy: An Essay on Interpretation. In this book Ricoeur attempted a deeper interpretation of Freud's analysis of individual and cultural psy...
Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5' exonuclease activities.

Mycobacterium smegmatis FenA is a nucleic acid phosphodiesterase with flap endonuclease and 5' exonuclease activities. The 1.8 A crystal structure of FenA reported here highlights as its closest homologs bacterial FEN-family enzymes ExoIX, the Pol1 exonuclease domain and phage T5 Fen. Mycobacterial FenA assimilates three active site manganese ions (M1, M2, M3) that are coordinated, directly and via waters, to a constellation of eight carboxylate side chains. We find via mutagenesis that the carboxylate contacts to all three manganese ions are essential for FenA's activities. Structures of nuclease-dead FenA mutants D125N, D148N and D208N reveal how they fail to bind one of the three active site Mn2+ ions, in a distinctive fashion for each Asn change. The structure of FenA D208N with a phosphate anion engaged by M1 and M2 in a state mimetic of a product complex suggests a mechanism for metal-catalyzed phosphodiester hydrolysis similar to that proposed for human Exo1. A distinctive feature of FenA is that it does not have the helical arch module found in many other FEN/FEN-like enzymes. Instead, this segment of FenA adopts a unique structure comprising a short 310 helix and surface β-loop that coordinates a fourth manganese ion (M4).
Rapid annotation of 3D medical imaging datasets using registration-based interpolation and adaptive slice selection

Accurate ground truth generation for 3D datasets is essential in many anatomy recognition and disease understanding applications. Interpolation techniques can substantially reduce the cost of manual segmentation for 3D images by only requiring a subset of 2D slices to be manually segmented, from which 3D segmentation is reconstructed through inter-slice label propagation. In this paper we present two enhancements, applying registration-based interpolation for 3D segmentation reconstruction and adaptive slice selection, to further speed up interpolation-based annotation. Comparing to shape-based interpolation methods, our technique can deliver accurate 3D anatomical segmentation with almost 50% reduction in the number of manually labeled slices.
Studies of the E. coli ATP synthase with a relocated R210 in subunit a

The ATP synthase of E. coli requires for function a conserved residue R210 in the membrane-bound, stator subunit a. Recent work has shown that ATP synthesis can be maintained if the conserved Arg i...
Dietary Fiber and Bile Acid Metabolism — An Update

Metabolism of bile acids plays a key role in the etiology of two of the most common causes of death, coronary heart disease and colon cancer. Bile acids are the major route of excretion of steroid from the body and thus a determinant of changes in sterol balance, a risk factor for coronary heart disease. Risk for colon cancer has been shown to increase with increased concentrations of bile acids in the colon, both in epidemiological studies in humans and in experimental animal studies. Dietary fiber plays a major role in regulating the metabolism of bile acids and altering risk for these diseases. However we know little of the specific mechanisms involved in the role played by dietary fiber in bile acid metabolism.
Discovering Business Intelligence Information by Comparing Company Web Sites

Ever since the beginning of the Web, finding interesting/useful information from the Web has been an important problem. Existing approaches mainly include keyword-based search, wrapper-based information extraction, Web query, and explicit user preferences. All these approaches essentially find relevant information using explicit specifications of the user. In this paper, we argue that this is insufficient. There is another type of information that is also of great interest, i.e., the unexpected information, which is unanticipated by the user. Finding unexpected information is important in many applications. For example, it is useful for a company to find unexpected information about its competitors. With more and more companies venturing into e-commerce and using the Web to promote their products and services, finding interesting information from these Web sites is increasingly becoming an important issue for business intelligence. Since the number of pages of a typical commercial site is large and there are also many relevant sites, it is very difficult for a human user to view each page to discover interesting/useful information. Automated assistance is needed. In this paper, we first study the issue of information interestingness in the context of the Web. We then propose a number of methods to help the user find various types of interesting (including unexpected) information from a Web site. A system (called WebCompare) based on the proposed methods has been implemented. Experimental results and applications show that the system is useful in practice and also efficient.
Available Bandwidth Estimation with Mobility Management in Ad Hoc Networks

Audio, video and multimedia applications are traffic type which is increasingly in current networks. Besides the convenience of mobile ad hoc networks consider the provision of quality of service (QoS) essential, that is why several projects have been undertaken to provide it. Among these projects for IEEE 802.11-based ad hoc networks the available bandwidth is one of the key criteria which have been treated. ABE is the last project that first estimate then reserve in second time the available bandwidth. But the mobility which is major criterion of wireless ad hoc networks is still not treated specifically either in ABE nor other previous projects. In this paper, we will unveil a new technique ABE-MM (Available Bandwidth Estimation with Mobility Management) which adopts the ABE method in the basic measurements, but treats the mobility problem in a specific way.
Screening tuber-bearing Solanum species for resistance to Helminthosporium solani

Silver scurf, caused byHelminthosporium solani, is an important disease of table stock and processing potatoes, for which few management strategies exist. Two hundred-twelve accessions of tuber-bearingSolarium species were screened for their response toH. solani. Tubers were inoculated in the laboratory with a spore suspension, incubated for 1 mo, and evaluated for infection using the number of conidiophore groups per square millimeter of sporulating tuber surface. Tubers with relatively low sporulation in the laboratory were retested using natural inoculum present in potato storages and assessed for infection. There were significant differences (P < 0.05) between accessions with both methods of inoculation. Some accessions ofSolanum demissum, S. chacoense, S. acaule, S. stoloniferum, S. oxycarpum, andS. hondelmannii consistently demonstrated low sporulation in laboratory and storage, suggesting partial resistance. Both methods of inoculation, laboratory and storage, were found to be correlated (ranging from r = 0.582,P= 0.006; to r = 0.925,P < 0.003).
Warm autoadsorption with enzyme-treated red blood cells

Patients demonstrating warm autoantibody specificity present serologic challenges for laboratory staff performing antibody identification in the blood bank. Autoantibody can be removed from plasma or serum by adsorption onto autologous red blood cells (RBCs) provided the patient has not been transfused in the previous 3 months. The adsorption process can be enhanced by enzyme pretreatment of autologous RBCs.
Cytoplasmic Dynein Dysfunction and Neurodegenerative Disease

Publisher Summary Active, directed transport along cytoplasmic microtubules is a characteristic feature of mammalian cells. The transport of organelles, vesicles, and proteins along the microtubule cytoskeleton is driven by both kinesins and cytoplasmic dynein. Neurons are uniquely vulnerable to defects in dynein function. Mutations in cytoplasmic dynein and its activator dynactin result in neurological defects in humans as well as in model organisms including drosophila and mice. The important role of the dynein motor in intracellular trafficking and transport makes it likely that defects in this pathway contribute to a number of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and Huntington’s disease (HD). The identification of cytoplasmic dynein as an essential minus-end-directed motor in higher eukaryotes has led to a much deeper understanding of the role of active transport in the neuron. This chapter reviews the critical roles dynein plays in neurons. Following this, it discusses the effects that dynein and dynactin mutations have on neuronal function. Finally, it deals with the neurodegenerative diseases in which dynein dysfunction is not the proximal cause but may be a key contributor to the pathological state. The significance of these questions to neurodegenerative disease is becoming increasingly clear with the identification of human mutations in the dynein-associated protein dynactin, Lis1, Rab7, and bIII spectrin, which is now a rapidly progressing field.
GPU-accelerated generation and rendering of multi-level voxel representations of solid models

Abstract Solid models traditionally use boundary-representation (B-rep) to define and model their geometry. However, performing modeling operations such as Boolean operations or computing point membership classification with B-rep is computationally intensive, since B-reps do not have volumetric information. Voxelized representations, on the other hand, can be extended to include volumetric information of solid models. However, in order to use voxelized representations for solid modeling, efficient methods for voxelizing a B-rep solid model needs to be developed. In this paper, we present GPU-accelerated methods for creating and rendering a multi-level voxelization of a solid model that can be used for modeling operations. We describe two GPU-accelerated algorithms; one for creating a multi-level voxelization given a B-rep of a solid model and another for ray casting to render the multi-level voxelization of the solid model. We describe compact and flat data structures that can be used to store the multi-level voxelization data and can be efficiently retrieved in parallel by GPU-algorithms for rendering and modeling operations. The GPU-accelerated multi-level voxelization method can generate models with an effective voxel count of up to 8 billion voxels. In addition, the GPU voxelization algorithm is more than 40x faster than the CPU implementation in generating the voxelization. Finally, we outline a few applications for the voxel representation, which include fast point-membership classification, volume computation, and collision detection.
Synthesis and Mechanochemical Activation of Ladderene-Norbornene Block Copolymers

We have recently reported a polymechanophore system, polyladderene (PLDE), which dramatically transforms into polyacetylene (PA) upon mechanical stimulation. Herein, we optimized conditions to synthesize unprecedented block copolymers (BCPs) containing a force-responsive block by sequential ring-opening metathesis polymerization of different norbornenes and bromoladderene. Successful extension from PLDE to other blocks required careful timing and low temperatures to preserve the reactivity of the PLDE-appended catalyst. The PLDE-containing BCPs were sonochemically activated into visually soluble PA with a maximum absorption λ ≥ 600 nm and unique absorption patterns corresponding to noncontinuous activation of ladderene units. Access to polymechanophore BCPs paves the way for new stress-responsive materials with solution and solid state self-assembly behaviors and incorporation of polymechanophores into other materials.
Mothering Brooklyn: Signs, sexuality, and gentrification under cover

Abstract This paper examines how Brooklyn retail signage represents how gentrifying women struggle for claiming space in public and the way in which different intersectional identity formations are used and implicated in transforming urban space. In exploring different ethnographic dimensions to retail storefronts, we show how women, many of whom are college-educated, married, and new mothers, play a significant role in redefining Brooklyn and cultural norms of motherhood more broadly. Yet, as newly arriving women emerge as key players in the gentrification project, they experience backlash against their public roles. We explore how women also employ race, inequality, and patriarchal notions of heteronormative sexuality as a cover for their public challenges to patriarchal power. Drawing on visual ethnography, interviews, and digital archival material we argue that the ambiguity of word play accomplishes both the pushing of normative boundaries as well as the protective cover of public meanings.
Feature selection in gait classification of leg length and distal mass

Abstract Technologies such as motion capture systems and force plates can aid in gait diagnosis and help identify the underlying differences between gait patterns. To support the most effective integration of these technologies in health professions, it is helpful to understand which features are most important in classification. Twenty individuals walked with combinations of an asymmetric leg length using a shoe with a small or large height and/or an asymmetric distal mass using a small or large ankle weight. These conditions changed the resultant gait of participants to impose asymmetric gait impairments. Different classifiers such as Support Vector Machines with different kernel functions were trained to classify leg length into 3 classes and distal mass into 5 classes using spatial-temporal, kinematic, and kinetic features, and evaluated for every combination of three features. Push-off force asymmetry was found to be an important feature in the classification of both leg length and distal mass. Asymmetry with regards to minimum knee angle, maximum hip extension, and the first vertical peak resulted in the best model for classifying leg length with an accuracy of 64.8%. Asymmetry with regards to braking force, push-off force, and vertical work resulted in the best model for classifying distal mass with an accuracy of 69.9%. The results suggest that the optimal features vary according to the specific impairment.
Successful auditory motor adaptation requires task-relevant auditory errors.

Feedback monitoring is essential for accurate speech production. By providing empirical results and a computational framework, we show that 1) the brain evaluates relevance of auditory errors and r...
Present Tense: Time, Madness, and Democracy

Focusing on images and affects surrounding temporality, this essay is an attempt to reflect on time itself as an experiential, qualitative category, in the midst of a time in American political culture that is by all accounts tense, uncertain, “interesting,” and (above all) crazy.
Origins of the Resting-State Functional MRI Signal: Potential Limitations of the “Neurocentric” Model

Resting-state functional connectivity (rsFC) is emerging as a research tool for systems and clinical neuroscience. The mechanism underlying resting-state functional MRI (rsfMRI) signal, however, remains incompletely understood. A widely held assumption is that the spontaneous fluctuations in blood oxygenation level-dependent (BOLD) signal reflect ongoing neuronal processes (herein called "neurocentric" model). In support of this model, evidence from human and animal studies collectively reveals that the spatial synchrony of spontaneously occurring electrophysiological signal recapitulates BOLD rsFC networks. Two recent experiments from independent labs designed to specifically examine neuronal origins of rsFC, however, suggest that spontaneously occurring neuronal events, as assessed by multiunit activity or local field potential (LFP), although statistically significant, explain only a small portion (∼10%) of variance in resting-state BOLD fluctuations. These two studies, although each with its own limitations, suggest that the spontaneous fluctuations in rsfMRI, may have complex cellular origins, and the "neurocentric" model may not apply to all brain regions.
Russia: The Officers of the Baltic Fleet

This chapter traces the evolution of the administration and officer corps of the Russian Baltic Fleet from its establishment by Peter the Great through the reign of Catherine the Great. It emphasizes the role that foreign-born officers played in its development, the efforts to recruit and train native-born Russian officers, and the deployment of the navy across the century’s wars. Peter the Great’s vision for the navy proved difficult to sustain and subsequent administrations struggled to find funds for it. Manning and revenue problems undermined its effectiveness, and foreign-born officers continued to play important roles right up until the end of the century.
Virtual Parity-Time Symmetry

Parity-time (PT) symmetry has recently been opening exciting directions in photonics, yet the required careful balance of loss and gain has been hindering its widespread applicability. Here, we propose a gain-free route to PT symmetry by extending it to complex-frequency excitations that can mimic gain in passive systems. Based on the concept of virtual absorption, extended here to implement also virtual gain, we implement PT symmetry in the complex-frequency plane and realize its landmark effects, such as broken phase transitions, anisotropic transmission resonances, and laser-absorber pairs, in a fully passive, hence inherently stable, system. These results open a path to establish PT symmetry and non-Hermitian physics in passive platforms.
A brief history of periodontics in the United States of America: Pioneers and thought-leaders of the past, and current challenges.

This paper summarizes historical events in periodontology in the United States over the past 200 years. The contributions of some of the key thought-leaders of the past are highlighted. Throughout the 20th century, the evolution of thought, leading to the views currently held regarding the pathogenesis and treatment of periodontal diseases, was significantly influenced by: (1) major changes in health-care education; (2) the emergence of periodontics as a specialty of dentistry; (3) the publication of peer-reviewed journals with an emphasis on periodontology; (4) formation of the National Institute of Dental and Craniofacial Research (NIDCR); and (5) expansion of periodontal research programs by the NIDCR. The two major future challenges facing periodontal research are development of a better understanding of the ecological complexities of host-microbial interactions in periodontal health and disease, and identification of the relevant mechanisms involved in the predictable regeneration of damaged periodontal tissues.
Economic Effects of a Potential Foodborne Disease: Potential Relationship between Mycobacterium Avium Subs. Paratuberculosis (MAP) in Dairy and Crohn’s in Humans

Welfare costs of a potential food shock were estimated by disseminating information to milk drinkers on the prevalence of Mycobacterium avium sub. paratuberculosis (MAP) in the U.S. milk supply, its potential linkage to Crohn’s disease in humans, and subsequent government intervention to minimize MAP in the milk supply. We found that 19.6% of milk consumers exposed to MAP information would stop milk consumption at current market prices, and that only 5% of those would return to their original milk consumption levels after the government intervention. Societal costs of the food shock after the intervention were estimated at $18.2 billion.
The Effect of Policy Responses to Infectious Disease on Feelings of Fear and Anxiety

To successfully address large-scale public health threats such as the novel coronavirus outbreak, policymakers need to limit feelings of fear and anxiety that threaten social order and political stability. We study how policy response to an infectious disease affects mass fear using data from a survey experiment conducted on a representative sample of the adult population in the United States (N=5,461). We find that fear and anxiety are strongly affected by the final policy outcome, relatively mildly by the severity of the initial outbreak, and minimally by policy response type and rapidity. This result holds across various subgroups of individuals regardless of their partisan identification, level of exposure to coronavirus, knowledge of the virus, and several other theoretically relevant characteristics.
Gamma irradiation effect studies on monolayer molybdenum disulfide on metallic substrates

Molybdenum disulfide (MoS2) is a two-dimensional material which has demonstrated semiconducting behavior [1]. Different kinds of irradiations create the defects in molybdenum disulfide (MoS2) structure, different types of irradiations modulate the density of sulfur vacancies in MoS2[1]. MoS2 based and other 2-D materials-based devices and sensors are used in harsh environments [1]. In [2] authors have demonstrated studies of gamma irradiation on mono layer graphene. To develop and fabricate the MoS2-based devices and sensors, nanoelectronics instrumentation such as Transmission Electron Spectroscopy (TEM), Scanning Electron Microscopy (SEM), Raman Spectroscopy, X-ray Photo-Electron Diffraction (XPS) techniques are required for characterization of MoS2. Moreover, these radiation techniques, have huge impacts on electronic and optical properties of MoS2 [3]. So, it is important to study irradiation effects on the crystal structure and properties of MoS2. In this work, Co-60 source was used for the irradiation, which has nominal irradiation dose 2.07 Gy/min (207 rad/Min) (±5%). We have irradiated gamma-rays on four samples of single-layer molybdenum disulfide over copper substrate. We exposed the irradiation dose of 1.0 kGy (100 krad), 1.75 kGy (175 krad), 2.65 kGy (265 krad) and 3.0 kGy (300 krad) of irradiations on sample number one, two, three and four respectively. Through the Raman Spectroscopy, we studied E12g, A1g peaks. A1g peak is at 403.6 cm-1 and E12g peak is at 384.7 cm-1 in pristine MoS2 Raman spectroscopy. Raman spectroscopy is nondestructive tool for characterization of S vacancies in MoS2.
Inappropriate outpatient antibiotic use in children insured by Kentucky Medicaid.

Objective To describe risk factors associated with inappropriate antibiotic prescribing to children. Design Cross-sectional, retrospective analysis of antibiotic prescribing to children, using Kentucky Medicaid medical and pharmacy claims data, 2017. Participants Population-based sample of pediatric Medicaid patients and providers. Methods Antibiotic prescriptions were identified from pharmacy claims and used to describe patient and provider characteristics. Associated medical claims were identified and linked to assign diagnoses. An existing classification scheme was applied to determine appropriateness of antibiotic prescriptions. Results Overall, 10,787 providers wrote 779,813 antibiotic prescriptions for 328,515 children insured by Kentucky Medicaid in 2017. Moreover, 154,546 (19.8%) of these antibiotic prescriptions were appropriate, 358,026 (45.9%) were potentially appropriate, 163,654 (21.0%) were inappropriate, and 103,587 (13.3%) were not associated with a diagnosis. Half of all providers wrote 12 prescriptions or less to Medicaid children. The following child characteristics were associated with inappropriate antibiotic prescribing: residence in a rural area (odds ratio [OR], 1.09; 95% confidence interval [CI], 1.07-1.1), having a visit with an inappropriate prescriber (OR, 4.15; 95% CI, 4.1-4.2), age 0-2 years (OR, 1.39; 95% CI, 1.37-1.41), and presence of a chronic condition (OR, 1.31; 95% CI, 1.28-1.33). Conclusions Inappropriate antibiotic prescribing to Kentucky Medicaid children is common. Provider and patient characteristics associated with inappropriate prescribing differ from those associated with higher volume. Claims data are useful to describe inappropriate use and could be a valuable metric for provider feedback reports. Policies are needed to support analysis and dissemination of antibiotic prescribing reports and should include all provider types and geographic areas.
Design of a High-Density Integrated Power Electronics Building Block (iPEBB) Based on 1.7 kV SiC MOSFETs on a Common Substrate

This paper presents the design of an integrated power electronics building block (iPEBB) for high-density systems. The design begins with exploring state-of-the-art substrates that will serve as the foundation for the iPEBB. Due to the integrated design, the substrate plays a vital role in the thermal, electrical, and mechanical performance, and contributes to the weight and reliability of the iPEBB. State-of-the-art organic direct bonded copper (ODBC) substrates are evaluated in this work. Multi-domain simulations are used to design the integrated SiC bridges to achieve a power loop inductance of 3.5 nH, a maximum temperature of 175 °C, and a weight of 16 kg. A half-bridge module prototype is fabricated and tested to provide insight into the substrate functionality and to aid in the refinement of the iPEBB concept.
Genes for NUE in rice: a way forward for molecular breeding and genome editing

Nitrogen is one of the most critical nutrients in rice production and increased rice productivity is attributed mostly to the nitrogen fertilizer responsive rice varieties. With its relevance to environment, breeding for nitrogen use efficiency is now a research priority in rice. Based on the physiological, biochemical and genetic studies, several genes have been identified for nitrogen uptake, transport, remobilization and assimilation. Many of the genes and gene families associated with tissues like root, shoot, leaf and panicle have been characterized under differential nitrogen conditions. Functional validation of the identified genes in nitrogen use efficiency, yield and other agro-morphological traits demonstrated their potential for deployment in rice breeding programs. In the present review, the information on possible genes associated with nitrogen use efficiency has been presented. The epigenetic regulation of genes including the non-coding RNA and new breeding technologies like genome editing have also been discussed for identification and validation of genes for NUE. We propose a combinatorial approach of deploying the information available for genes reported to be associated with NUE of rice by haplotyping, allele mining, spatial and temporal expression analyses, gene networking and validation through genome editing towards development of high yielding rice varieties under optimum nitrogen.
Palladium-catalyzed annulation of internal alkynes

75 Introduction 75 Results and Discussion 77 Experimental Section 85 Acknowledgemait 92 References 93 GENERAL CONCLUSIONS 96