cssi/SciSciGPT-SciSciNet huggingface dataset:
MMPI Differencecs Between LDS Parents of Disturbed and Nondisturbed Children

Much of the underlying theoretical rationale of childhood psychopathology has pointed to parents as causal agents (Lowitt, 1975). The hypothesis that parental attitudes and behaviors playa major role in the shaping of personality and in the development of emotional disturbances in children is a primary assumption underlying most diagnostic and prognostic formulations in child clinical settings (Karson and Markenson, 1973). This view has been primarily supported by clinical evidence such as case histories and psychiatric interviews (Liverant, 1959). What little experimental research that has been done relating parental factors to emotional disturbance in children has been inconclusive and frequently contradictory (Frank, 1965). Although there is a relatively large amount of research which points towards the importance of parental attitudes and personalities upon child behavior, the current author is not aware of any studies that directly investigate the differences between parents of disturbed and nondisturbed children using an objective instrument. The need for research and effective treatment and educational procedures is evidenced by the growing number of concerns of school personnel and parents, as well as the prevalence of journal articles dealing with the emotionally disturbed child (Walton, 1975). In developing effective treatment procedures, it is necessary to first consider the conditions that are conducive to the development of difficulties. These conditions, in turn, must be related to the conditions of helping (Carkhuff, 1970). It is in this light that the current research was undertaken. Subjects and Method of Data Collection The subjects were selected from the members of The Church of Jesus Christ of Latter-day Saints (LOS) residing in the Metropolitan Washington, D.C. area. The area ecclesiastical leaders were contacted and furnished with applications for participation in a research project dealing with special-needs children. The population consisted of those LOS parents of emotionally disturbed children whose applications were returned and accepted based upon specified
Improving the efficiency and robustness of intrusion detection systems

With the increase in the complexity of computer systems, existing security measures are not enough to prevent attacks. Intrusion detection systems have become an integral part of computer security to detect attempted intrusions. Intrusion detection systems need to be fast in order to detect intrusions in real time. Furthermore, intrusion detection systems need to be robust against the attacks which are disguised to evade them. We improve the runtime complexity and space requirements of a host-based anomaly detection system that uses q-gram matching. q-gram matching is often used for approximate substring matching problems in a wide range of application areas, including intrusion detection. During the text pre-processing phase, we store all the q-grams present in the text in a tree. We use a tree redundancy pruning algorithm to reduce the size of the tree without losing any information. We also use suffix links for fast linear-time q-gram search during query matching. We compare our work with the Rabin-Karp based hash-table technique, commonly used for multiple q-gram matching. To analyze the robustness of network anomaly detection systems, we develop a new class of polymorphic attacks called polymorphic blending attacks, that can effectively evade payload-based network anomaly IDSs by carefully matching the statistics of the mutated attack instances to the normal profile. Using PAYL anomaly detection system for our case study, we show that these attacks are practically feasible. We develop a formal framework which is used to analyze polymorphic blending attacks for several network anomaly detection systems. We show that generating an optimal polymorphic blending attack is NP-hard for these anomaly detection systems. However, we can generate polymorphic blending attacks using the proposed approximation algorithms. The framework can also be used to improve the robustness of an intrusion detector. We suggest some possible countermeasures one can take to improve the robustness of an intrusion detection system against polymorphic blending attacks.
Nanoimprint of large-area optical gratings on a conventional photoresist using a teflon-coated nanoimprint mold

Nanoimprint Lithography is a promising high-throughput technology for the fabrication of optical nanostructures over large areas in the centimeter range. However, there are limitations (cost, proprietary and tool specific) of the commercial transfer resist. In this work, the photo-resist AZ1518 is investigated as a viable nanoimprint resist mask with a tefloncoated silicon mold. The results are comparable with a commercial nanoimprint resist. To our knowledge, the application of a conventional photoresist as the nanoimprint mask with teflon-coated mold is novel, providing a critical solution for cost-effective, flexible and high-throughput fabrication of optical nanostructures over large areas. Periodic gratings with lateral width of 100 nm and 200 nm pitch have been fabricated using this approach. The nanoimprint process parameters (pressure and temperature) are optimized to improve the release of the mold from the resist. In addition, the Teflon-coated mold improves the release process to avoid tearing of the mask.
People of my side ≈ people of the other side

In this philosophical inquiry into the foundations of Xavante mathematical thought, numbers emerge as categories structured by social praxis in central Brazil. Clans, moieties, age-sets, and specific kin relations can be viewed as conventional symbols, or numerals, representing essential constituencies of the Xavante socionumerical system. As in other Ge-speaking societies of the Brazilian Amazon, Xavante numbers catalyze a set of presuppositions about dialectical mathematical systems whose rationality is informed by the pervasive dualism that governs social interaction for an estimated 8,000 Xavante today. The binary nature of this numerical system is a product of an omnipresent dialectical view of the world, always oscillating between an “us” and a “them”—or people of my side ≈ people of the other side. Accordingly, a unit is defined as the union of 2 fundamental parts, and numerical place value assumes the significance of reciprocal social relationships. The dialectical association of beings, human or not, material or symbolic, within the dynamism of Xavante dualism synthesizes these and other key ideas about the philosophy of Gě mathematical thought.
Applying a Developmental-Ecological Framework to Sickle Cell Disease Transition

Children’s Healthcare of Atlanta, Atlanta, Georgia and Emory UniversityTransitioning from pediatric to adult care is a challenging process for adolescents withsickle cell disease (SCD). There is a critical need for well-designed and practicallyadaptable SCD transition programs that are compatible within the social and culturalcontext of the individual. The purpose of this article is to outline the design of atheoretically informed intervention to facilitate successful transition for adolescents andyoung adults (AYAs) diagnosed with SCD. The authors propose and describe the useof a developmental–ecological framework in creating and implementing the Sickle CellDisease–Age Based Curriculum for Transition (SCD-ABC). The SCD-ABC Transitionprogram’s framework begins at birth with the parent–caregiver and spans throughouta child’s development into young adulthood. This program involves a multidisciplinaryteam approach with collaboration from pediatric and adult medical providers, familyand peers, social services, the community, and adult mentors living with SCD. The goalof this program was to foster increased disease knowledge and self-efﬁcacy for AYAs
Bleomycin-induced nodular pulmonary fibrosis masquerading as metastatic testicular cancer

Bleomycin has become an important component of combination chemotherapy, particularly in the treatment of metastatic testis carcinoma. Pulmonary toxicity is a major risk and irreversible pulmonary fibrosis or even death may result from its use. Rarely diffuse fibrosis may lead to discrete nodularity mimicking pulmonary metastasis. We report such a case, and discuss the various clinical, radiographic and histopathological forms of bleomycin-induced pulmonary toxicity.
Accessibility Implementation for Disabled Students in PMBOLD Environments

Project management theory provides an organized, cost-effective approach to providing an accessible e-learning environment. Such a collaborative project has the opportunity to bring together such professionals as instructional designers, disability services staff, and institutional researchers. Accessibility as an afterthought is a costly approach, and disabled students are a large enough minority to seek equality of opportunity. E-learning accessibility empowers the individual by providing educational content in formats that not only encourage collaboration and learning, but also reduce frustration and develop a sense of inclusiveness. A project manager who understands the importance of e-learning accessibility will be able to grow the project from the ground up in a manner that empowers the disabled, while benefiting all learners.
A non-autonomous bursting model for neurons

Certain mammalian visual neurons exhibit On and Off responses when given a light stimulus. In addition to these responses, [51] showed that for retinal ganglion cells, the neuron will also exhibit a Mixed response when given two simultaneous stimuli in different regions of the cell's receptive field. This Mixed response is a nonlinear combination of the On and Off responses. In this dissertation, a single cell model which can reproduce On, Off, and Mixed responses is developed and examined using leading order analyses and averaging. This model is developed from a current balance equation which includes a non-autonomous input I( t), and consists of three coupled, first-order nonlinear differential equations which describe the dynamics of the membrane potential of the cell. When I(t) is assumed to be a constant current pulse, the On and Off responses can be reproduced but will depend on both the duration and the amplitude of the input. When I(t) is assumed to be monotone slowly decreasing, the model can reproduce the nonlinear properties for two simultaneous stimuli. In this dissertation, conditions which will guarantee each type of response will be found using the different subsystems of the model.
Dyadic Product Formula Representations of Confidence Measures and Decision Rules for Dyadic Data Set Samples

A methodology for representing and computing confidence distributions for parametric representations of sets of samples of data is presented. The method assumes that the universe of the data samples is a dyadic set whose dyadic structure is an ordered binary tree of subsets of the universe with a measure defined on the dyadic sets. In this case the samples can be represented as the set of product coefficient parameters for the dyadic product formula representing the measure. If a dyadic structure is defined on the universe of product coefficient parameters, which is a high-dimensional cube, and a measure is defined on the dyadic sets of the cube, a confidence measure on the set of parameters is determined whose product formula can be determined by computing its parameters. When the original samples of data are labeled, decision rules based on their confidence distributions can be defined. The methodology is demonstrated on an a 12 dimensional network time series with 6 sources.
Things That Are Eternal

The fundamental idea of the eternal is that it is not conditioned by time and not subject to the relations of time. More briefly, it is free from the conditions of time. Although the concept of the timeless eternal is hedged about with paradox, at least or especially in its religious application, the concept as that which is not conditioned by time or free from the conditions of time is clear enough to be grasped. But are there any things that are eternal in this sense? Or, more circumspectly, what things have been said with seriousness to be eternal? In this chapter, our effort is fairly modest. It is simply to observe some of the various things that over time have been designated eternal in one or another area of human concern, culture, or religion.
Scaphoid Fractures: Nonunion and Malunion.

The treatment of scaphoid nonunion and malunions has undergone a considerable transition since the 1960 modification of Matti's technique by Russe.1 We present a review of articles with clear data on union rates and functional status to review the current methods of treatment for scaphoid nonunion and malunion.
A study on designing effective introductory materials for information visualization

Designing introductory materials is extremely important when developing new information visualization techniques. All users, regardless of their domain knowledge, first must learn how to interpret the visually encoded information in order to infer knowledge from visualizations. Yet, despite its significance, there has been little research on how to design effective introductory materials for information visualization. This paper presents a study on the design of online guides that educate new users on how to utilize information visualizations, particularly focusing on the employment of exercise questions in the guides. We use two concepts from educational psychology, learning type (or learning style) and teaching method, to design four unique types of online guides. The effects of the guides are measured by comprehension tests of a large group of crowdsourced participants. The tests covered four visualization types (graph, scatter plot, storyline, and tree map) and a complete range of visual analytics tasks. Our statistical analyses indicate that online guides which employ active learning and the top-down teaching method are the most effective. Our study provides quantitative insight into the use of exercise questions in online guides for information visualizations and will inspire further research on design considerations for other elements in introductory materials.
MC-MIMO radar: Recoverability and performance bounds

It was recently shown that low rank matrix completion theory can be employed for designing new sampling schemes in the context of MIMO radars, which can lead to the reduction of the high volume of data typically required for accurate target detection and estimation. This paper focuses on the performance of matrix completion in colocated MIMO radar systems equipped with Uniform Linear Arrays (ULAs). Exploiting the particular structure of the received data matrix, we present novel theoretical results showing that its coherence is both asymptotically and approximately optimal with respect to the number of antennas of the arrays involved and further, that the data matrix is recoverable using a subset of its entries with minimal cardinality.
Serologic and Phenotypic Analysis of Blood Types Via Silicon Nanophotonics

Tens of millions of donor and patient samples are tested yearly to establish blood type compatibility between donor and recipient and to protect recipients from blood-borne infectious diseases. Blood type testing, particularly donor testing, is traditionally based in centralized clinical laboratories. However, current blood typing methods are encumbered by reagent availability, cost, technical training requirements, and time, placing a costly burden on the medical system. To address practical needs in blood typing, we have developed a multiplexed blood analysis platform using a low-cost and scalable silicon photonic biochip. This study investigates the use of silicon microring sensors to capture, detect, and quantify specific red blood cell (RBC) membrane antigens and anti-blood type antibodies from blood. To validate ABO blood phenotyping, microring resonators were streptavidin coated and functionalized with biotinylated anti-A IgM or biotinylated anti-B IgM antibodies. First, the response of anti-A/B functionalized microring resonators to characterized RBC membranes (RBC ghosts, 108 cells/ml) were measured in real-time (Figure 1). The biosensor arrays also exhibited minimal non-specific adsorption of RBC membrane fragments to the sensor surface. Microring resonators were shown to be suitable for identifying RBC ABO phenotype from donor blood samples. For ABO serologic analysis, silicon chips were functionalized with synthetic multivalent polymeric blood group antigens to serve as capture elements for circulating anti-ABO antibodies. Each chip also had sensors functionalized with biotinylated Protein A (btn-ProtA) and a biotinylated polyacrylamide polymer scaffold (btn-paa) to serve as on-chip positive and negative controls, respectively. The multiplexed biosensor chips were exposed to 100mL of plasma, followed by an anti-human-IgM antibody to enhance detection and quantification of antibodies bound to the surface. The resonance shift in each microring resonator was monitored over time, and the sensor response of the polymeric A and B blood group antigens was normalized to the control sensors. Figure 2 illustrates the levels of bound anti-A and anti-B for a panel of donor blood samples with varying ABO blood type, expressed as a relative shift in sensor resonance wavelength. These results demonstrate the detection of the ‘naturally occurring9 anti-A/B IgM antibodies for each respective ABO blood type. We have demonstrated that microring resonator biosensor arrays can quantitatively determine the donor ABO phenotypic and serologic status while incorporating on-chip controls for process standardization. Our work serves as proof-of-concept that a multiplexed silicon nanophotonics platform can rapidly detect both RBC antigens and anti-RBC antibodies in biological samples. This method has the potential for broad applicability in hematology and transfusion medicine for blood typing, quantitative monitoring of specific antibodies, and pathogen screening. Disclosures No relevant conflicts of interest to declare.
Impact of future climate policy scenarios on air quality and aerosol-cloud interactions using an advanced version of CESM/CAM5: Part II. Future trend analysis and impacts of projected anthropogenic emissions

Abstract Following a comprehensive evaluation of the Community Earth System Model modified at the North Carolina State University (CESM-NCSU), Part II describes the projected changes in the future state of the atmosphere under the representative concentration partway scenarios (RCP4.5 and 8.5) by 2100 for the 2050 time frame and examine the impact of climate change on future air quality under both scenarios, and the impact of projected emission changes under the RCP4.5 scenario on future climate through aerosol direct and indirect effects. Both the RCP4.5 and RCP8.5 simulations predict similar changes in air quality by the 2050 period due to declining emissions under both scenarios. The largest differences occur in O3, which decreases by global mean of 1.4 ppb under RCP4.5 but increases by global mean of 2.3 ppb under RCP8.5 due to differences in methane levels, and PM10, which decreases by global mean of 1.2 μg m−3 under RCP4.5 and increases by global mean of 0.2 μg m−3 under RCP8.5 due to differences in dust and sea-salt emissions under both scenarios. Enhancements in cloud formation in the Arctic and Southern Ocean and increases of aerosol optical depth (AOD) in central Africa and South Asia dominate the change in surface radiation in both scenarios, leading to global average dimming of 1.1 W m−2 and 2.0 W m−2 in the RCP4.5 and RCP8.5 scenarios, respectively. Declines in AOD, cloud formation, and cloud optical thickness from reductions of emissions of primary aerosols and aerosol precursors under RCP4.5 result in near surface warming of 0.2 °C from a global average increase of 0.7 W m−2 in surface downwelling solar radiation. This warming leads to a weakening of the Walker Circulation in the tropics, leading to significant changes in cloud and precipitation that mirror a shift in climate towards the negative phase of the El Nino Southern Oscillation.
Ketamine Inhibition of Pentameric Ligand-Gated Ion Channels - Insights from Molecular Dynamics Simulations

The anesthetic ketamine is well known as a non-competitive antagonist of N-methyl-D-aspartate receptors (NMDARs). However, not all the clinical effects of ketamine can be fully explained by its inhibition of NMDARs. An alternative mode of ketamine action is through inhibition of pentameric ligand-gated ion channels (pLGICs), such as nicotinic acetylcholine receptors. Ketamine inhibits the bacterial pLGIC from Gloeobacter violaceus (GLIC) and the ketamine-GLIC co-crystallized structure was determined previously.
The dynamics and prevention of stress-induced burnout in athletics.

SUMMARY Burnout is defined as a stress-induced syndrome involving cognitive, emotional, and behavioral factors. The dynamics of stress and burnout are described, as are preventive measures that can be taken to reduce the likelihood of burnout among athletes, coaches, administrators, and sports medicine professionals. These measures involve changes in situational factors known to produce burnout as well as the development of coping skills that can be used to reduce the impact of environmental stressors.
Interaction of proliferating cell nuclear antigen with PMS2 is required for MutLα activation and function in mismatch repair

Eukaryotic MutLα (mammalian MLH1–PMS2 heterodimer; MLH1–PMS1 in yeast) functions in early steps of mismatch repair as a latent endonuclease that requires a mismatch, MutSα/β, and DNA-loaded proliferating cell nuclear antigen (PCNA) for activation. We show here that human PCNA and MutLα interact specifically but weakly in solution to form a complex of approximately 1:1 stoichiometry that depends on PCNA interaction with the C-terminal endonuclease domain of the MutLα PMS2 subunit. Amino acid substitution mutations within a PMS2 C-terminal 721QRLIAP motif attenuate or abolish human MutLα interaction with PCNA, as well as PCNA-dependent activation of MutLα endonuclease, PCNA- and DNA-dependent activation of MutLα ATPase, and MutLα function in in vitro mismatch repair. Amino acid substitution mutations within the corresponding yeast PMS1 motif (723QKLIIP) reduce or abolish mismatch repair in vivo. Coupling of a weak allele within this motif (723AKLIIP) with an exo1Δ null mutation, which individually confer only weak mutator phenotypes, inactivates mismatch repair in the yeast cell.
Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.

ERK is the effector kinase of the RAS-RAF-MEK-ERK signaling cascade, which promotes cell transformation and malignancy in many cancers and is thus a major drug target in oncology. Kinase inhibitors targeting RAF or MEK are already used for the treatment of certain cancers, such as melanoma. Although the initial response to these drugs can be dramatic, development of drug resistance is a major challenge, even with combination therapies targeting both RAF and MEK. Importantly, most resistance mechanisms still rely on activation of the downstream effector kinase ERK, making it a promising target for drug development efforts. Here, we report the design and structural/functional characterization of a set of bivalent ERK inhibitors that combine a small molecule inhibitor that binds to the ATP-binding pocket with a peptide that selectively binds to an ERK protein interaction surface, the D-site recruitment site (DRS). Our studies show that the lead bivalent inhibitor, SBP3, has markedly improved potency compared...
Assessment of tumor hypoxia in BEV resistant GBM using FMISO 18F-PET and MRI.

2045Background: Glioblastoma (GBM) is the most common malignant brain tumor in adults, and is characterized by poor survival and marked resistance to treatment. Hypoxic volume is directly correlate...
A transformerless single-phase utility interface converter to attenuate common-mode voltage for DC microgrid

DC power distribution gains popularity in future residential, renewable energy, transportation and data centers. Such dc system can be connected to ac system through bidirectional interface converter. Compared with isolated converters, transformerless solutions have the advantages of higher power density, efficiency, and lower cost. One concern about the non-isolated connection is the coupled common-mode voltage through ground and the resultant leakage current. In this paper, a two-stage cascaded single-phase ac-dc converter connecting 380 V bipolar dc system and 240 V split-phase ac system is used as an example to discuss the common-mode voltage attenuation. The cascaded converter uses full-bridges for both the ac-dc and the dc-dc stages to achieve decoupled common-mode voltage control. A common-mode equivalent circuit is established to analyze the origin of low-frequency common-mode voltage from the utility and high-frequency noise from the switching behavior of power converters. To attenuate high-frequency noise, a floating common-mode noise filter is connected across the ac and dc ports to contain the EMI noise within the converter. The low-frequency common-mode voltage is controlled by applying a common-mode duty cycle injection method to the full-bridge dc-dc stage. A 5 kW converter prototype is built to validate the attenuation method. The resultant dc bus voltage is symmetric to the ground and suitable for bipolar dc power distribution systems.
Financing dental services in the US: best practice model

The purposes of this paper are to examine the financing of dental services and determine the best practice model in response to the shift of dental services provided from the reduction of manufacturing practices and an increase in service-related activities. This paper discusses the three models used in financing of oral health care services including the Need, Utility or Market, and Program models. Financing dental services now utilizes many types of arrangements including two, third, and fourth-party relationships. All have impacted upon the Market model to modify the traditional, patient-provider relationship in financing dental care services. Each has separate philosophical and political agendas in achieving oral health goals. An increase in demand of dental services due to the retention of teeth in older adults and to the level of dental care desired by the public in general, new variations of the Market model are emerging. A Pragmatic model and its corollary, the Governmental model, are presented as the best model for financing dental services in the US to all segments of the service population for dentistry. It combines the contraposed philosophical and political agendas that exist in a pluralistic society.
Optimal Size of a Cylindrical Pore for Post-Combustion CO2 Capture

Pore size is an essential factor in controlling gas sorption in porous separation media. Overlap of the potential energy surface (PES) of CO2 interacting with a cylindrical pore wall can be used to tune gas sorption inside a porous material, but how such overlap can benefit post-combustion CO2 capture has not been fully addressed from a computational perspective. Here we use van der Waals density functional (vdW-DF) theory to assess the overlap of PES of CO2 inside cylindrical pores as represented by carbon nanotubes (CNTs) of different diameters. Then we employ grand-canonical Monte Carlo simulations to obtain the adsorption capacity and selectivity of a CO2/N2 mixture with a CO2 partial pressure of 0.15 atm at room temperature. We find that the maximum PES overlap and maximum amount of CO2 adsorbed are both achieved at a CNT diameter or cylindrical pore size of 7.8 A, which corresponds to an accessible pore size of 4.4 A. Further investigation of N2 adsorption corroborates the idea of PES overlap. GCMC ...
Sexual and Gender Minority Health Disparities as a Social Issue: How Stigma and Intergroup Relations Can Explain and Reduce Health Disparities

Sexual and gender minorities experience disparities in mental and physical health often attributed to structural discrimination through policies that do not promote equal rights and interpersonal–intrapersonal processes. Social issues research on stigma and intergroup relations can explicate the intervening processes that explain health. In this introduction to the special issue entitled Translating Stigma and Intergroup Relations Research to Explain and Reduce Sexual and Gender Minority Health Disparities, we call social issues researchers to focus their work on sexual and gender minority stigma and intergroup relations processes in order to understand and ultimately reduce health disparities.
Persistence of pain quality in community-dwelling older adults with chronic non-cancer pain.

Abstract Longitudinal assessment of chronic geriatric pain is complicated by an age-associated plateau in pain severity and increase in widespread pain, calling for innovative measures such as pain quality descriptors that characterize how pain may feel. We characterized persistence of pain quality and its relation to severity, activity interference and distribution of sites, in a population-based sample of adults aged≥70 years with chronic pain (n = 398). Persistent pain quality was defined as reporting descriptors within the same category: sensory, cognitive/affective, or neuropathic at baseline and 18 months. A count variable indicated number of persistent categories. Pain quality was highly persistent. Adjusted for baseline covariates, individuals endorsing 3 persistent categories were 2-2.5x more likely to experience more widespread pain at 18 months compared to fewer persistent categories. No associations were noted in changes in pain severity or interference. A comprehensive pain assessment that includes diverse pain quality descriptors may improve individualized pain management.
Experience with pharmacologic leeching with bivalirudin for adjunct treatment of venous congestion of head and neck reconstructive flaps.

Objectives The goal of this study was to review the feasibility of local bivalirudin injection for adjunct treatment of venous congestion of head and neck reconstructive flaps. Methods A retrospective chart review of patients who underwent bivalirudin treatment for venous congestion of head and neck reconstructive flaps in a single institution from September 1, 2012 to September 1, 2015 was undertaken. Individuals were treated with variable number of intradermal injections directly into the flap followed by a small skin incision to allow extended passive bleeding. The main outcome measure was improvement of flap congestion. Results Ten patients with free flap reconstruction (4 anterolateral thigh flaps, 2 pectoralis major flaps, 2 fibula osseocutaneous flaps, 1 supraclavicular flap, and 1 radial forearm free flap) of various head and neck defects underwent treatment with bivalirudin. Bivalirudin injections were utilized as adjunct therapy in 6 patients. Two individuals underwent alternate therapy for venous congestion immediately following injection and therefore the efficacy could not be assessed. Of the 8 remaining flaps, 4 developed partial necrosis, and 1 developed complete necrosis requiring additional reconstruction. Two individuals required blood transfusions during bivalirudin treatment. Conclusions Bivalirudin is a safe and feasible adjunct therapy for treatment of flap congestion. It may serve as a useful alternative to traditional leech therapy, as bivalirudin negates the need for antibiotic prophylaxis, eliminates the psychological aversion associated with leech therapy, and avoids the potential for leech migration. Further work to determine the efficacy of bivalirudin to standard leech therapy is warranted.
Learning and predicting on-road pedestrian behavior around vehicles

Pedestrian safety is critical from the standpoint of autonomous vehicles. We address the problem of reliable long term (< 5 sec) prediction of on-road pedestrian trajectories using track histories generated with two vehicle mounted cameras. Due to the relatively unconstrained nature of pedestrian motion, model based trajectory prediction approaches become unreliable for long term prediction. Data-driven approaches offer a viable alternative, but are susceptible to bias toward dominant motion patterns in the training set. This leads to poor prediction for under-represented motion patterns, which can be disastrous from a safety perspective. In this work, we extend the Variational Gaussian Mixture model (VGMM) based probabilistic trajectory prediction framework in [1]. We sub-categorize pedestrian trajectories in an unsupervised manner based on their estimated sources and destinations, and train a separate VGMM for each sub-category. We show that the sub-category VGMMs outperform a monolithic VGMM of equivalent complexity, especially for longer prediction intervals. We further analyze the errors made by the two models and the distributions learnt by them, to demonstrate that the sub-category VGMMs better model under-represented motion patterns.
Discriminative Probabilistic Framework for Generalized Multi-Instance Learning

Multiple-instance learning is a framework for learning from data consisting of bags of instances labeled at the bag level. A common assumption in multi-instance learning is that a bag label is positive if and only if at least one instance in the bag is positive. In practice, this assumption may be violated. For example, experts may provide a noisy label to a bag consisting of many instances, to reduce labeling time. Here, we consider generalized multi-instance learning, which assumes that the bag label is non-deterministically determined based on the number of positive instances in the bag. The challenge in this setting is to simultaneous learn an instance classifier and the unknown bag-labeling probabilistic rule. This paper addresses the generalized multi-instance learning using a discriminative probabilistic graphical model with exact and efficient inference. Experiments on both synthetic and real data illustrate the effectiveness of the proposed method relative to other methods including those that follow the traditional multiple-instance learning assumption.
A perspective on the impact on safety of the rate of change of technology used in patient care

The application of electronic medical technology not only increased the capabilities of medical staff to care for patients but also brought some new safety-related risks and systems engineering issues, and technology management programs have evolved over the years in response. Software based medical technology should increase capabilities as well, and their impact on technology management programs needs examination.
Legal Writing Scholarship, Making Strange, and the Aesthetics of Legal Rhetoric

From the article: Some of the central issues addressed in the Mercer Law School Symposium on Legal Writing involved questions about the scholarship potential of the discipline of legal writing. Those on the fringe of the academy, as legal writing professors are now and as clinicians were in the sixties, often offer the clearest perspective on it, and, in the case of the legal academy, on the practice itself. What scholarship, I wondered as I listened to the speakers, would best take advantage of this privileged perspective and of legal writing’s necessary focus on rhetoric? There are at least two ways of approaching this question, both of which I want to use here, and these two ways can be related one to the other as I will try to do here as well. The first is to wonder what subjects for the discipline are most naturally generated by teaching it. Here, I will pursue this approach immodestly by trying to display how my own recent scholarship could have naturally arisen (and to some extent it did naturally arise) from teaching an Advanced Legal Writing section as part of the Legal Writing Certificate Program at Mercer. The second approach is normative: What subjects should legal writers contribute to the academy and why? For the first I will ask you to join me in an imagined internal monologue as I wonder about what to say to my students in my Advanced Legal Writing section. For the second I will offer an argument that what emerges from this internal monologue, and, I believe, would also emerge from the similar internal monologues of other legal writing professors, can offer a central perspective for legal writing scholarship, a perspective that could define it. It is a perspective much needed, I will argue very briefly in conclusion, by both the legal academy and the practice. Perhaps it would not be an exaggeration to say: desperately so.
History Note: Machining, Strain Gages, and a Pulse-Heated Kolsky Bar

A special Kolsky bar apparatus with the capability to pulse heat the sample was built at the National Institute of Standards and Technology (NIST). This Kolsky bar laboratory’s initial purpose was to measure dynamic material properties in support of machining analysis research. Machining is a high-strain, high-strain-rate, high-temperature, high-heating-rate process. Developing mathematical models to analyze machining processes presents unique challenges, including appropriate material stress-strain relationships. The NIST system can heat a sample to over 1000 C in less than a second immediately prior to a Kolsky bar impact test. Although there are many traditional Kolsky bars in operation, the ability to achieve a very rapid temperature increase by electrical resistive heating is unique. The development and construction of this laboratory involved cooperative effort of several researchers from different NIST divisions. The work benefitted from a rich history of strain measuring research at the National Bureau of Standards (NBS), now named NIST, as well as drawing on a long history of interaction with the Society for Experimental Mechanics (SEM). .
580µW 2.2-2.4GHz Receiver with +3.3dBm Out-of-Band IIP3 for IoT Applications

A low-power 2.2-2.4GHz receiver front-end for Internet-of-Things applications, is presented. The front-end, fabricated in a 28nm bulk CMOS process, consists of a capacitively cross coupled CG-LNA, with translational positive feedback from baseband to RF through a 4-phase switching mixer, providing RF filtering and matching, in conjunction with a 1:4 transformer. The prototype achieves a NF of 11.9dB and in-band IIP3 of −6.5dBm, while consuming 0.58mW power, including the buffers to drive the mixer switches. Additionally, it achieves an out-of-band IIP3 of +3.3dBm.
Critique or Collectivity? Communicative Capitalism and the Subject of Politics

Communicative capitalism replaces the use value of political speech with its exchange value: is it interesting, timely, or outrageous enough to share? From the perspective of liberal democracy, this development looks like a disaster. From a communist perspective, this is a new opening to the force of the many.
A novel approach to understanding bird communities using informed diversity estimates at local and regional scales in northern California and southern Oregon.

Assessment and preservation of biodiversity has been a central theme of conservation biology since the discipline's inception. However, when diversity estimates are based purely on measures of presence-absence, or even abundance, they do not directly assess in what way focal habitats support the life history needs of individual species making up biological communities. Here, we move beyond naive measures of occurrence and introduce the concept of "informed diversity" indices which scale estimates of avian species richness and community assemblage by two critical phases of their life cycle: breeding and molt. We tested the validity of the "informed diversity" concept using bird capture data from multiple locations in northern California and southern Oregon to examine patterns of species richness among breeding, molting, and naive (based solely on occurrence) bird communities at the landscape and local scales using linear regression, community similarity indices, and a Detrended Correspondence Analysis (DCA). At the landscape scale, we found a striking pattern of increased species richness for breeding, molting, and naive bird communities further inland and at higher elevations throughout the study area. At the local scale, we found that some sites with species-rich naive communities were in fact species-poor when informed by breeding status, indicating that naive richness may mask more biologically meaningful patterns of diversity. We suggest that land managers use informed diversity estimates instead of naive measures of diversity to identify ecologically valuable wildlife habitat.
A Partially Rule-Based Approach to AMR Generation.

This paper presents a new approach to generating English text from Abstract Meaning Representation (AMR). In contrast to the neural and statistical MT approaches used in other AMR generation systems, this one is largely rule-based, supplemented only by a language model and simple statistical linearization models, allowing for more control over the output. We also address the difficulties of automatically evaluating AMR generation systems and the problems with BLEU for this task. We compare automatic metrics to human evaluations and show that while METEOR and TER arguably reflect human judgments better than BLEU, further research into suitable evaluation metrics is needed.
Tracking Underground Moving Targets with Wireless Seismic Networks

Monitoring and tracking the underground moving target have many important applications, such as homeland security and defense applications. A wireless seismic network is designed to sense the seismic wave generated by the moving target and locate the target based on Reverse Time Migration (RTM) method. A new Gaussian Beam Migration (GBM) algorithm is used to improve the traditional RTM algorithm. The GBM-RTM method is a time-frequency domain algorithm, where the complex time domain calculation is transformed to a simple frequency domain calculation. By using GBM-RTM method, we accelerate the computation and reduce the communication cost. Through the extensive simulations and experiments, we demonstrate the trajectory tracking of the moving underground targets. The stability and accuracy of our proposed localization algorithms are also evaluated.
Brain White Matter: A Substrate for Resilience and a Substance for Subcortical Small Vessel Disease

Age-related brain white matter disease is a form of small vessel disease (SVD) that may be associated with lacunar and other small subcortical infarcts, cerebral microbleeds, and perivascular spaces. This common form of cerebrovascular disease may manifest clinically as cognitive impairment of varying degrees and difficulty with mobility. Whereas some persons show cognitive decline and mobility failure when there are brain white matter hyperintensities (WMH) and acute stroke, others recover, and not everyone with brain white matter disease is disabled. Thus, repair or compensation of brain white matter may be possible, and furthermore, certain vascular risks, such as raised blood pressure, are targets for prevention of white matter disease or are administered to reduce the burden of such disease. Vascular risk modification may be useful, but alone may not be sufficient to prevent white matter disease progression. In this chapter, we specifically focus on WMH of vascular origin and explore white matter development, plasticity, and enduring processes of myelination across the health span in the context of experimental and human data, and compare and contrast resilient brain white matter propensity to a diseased white matter state. We conclude with thoughts on novel ways one might study white matter resilience, and predict future healthy cognitive and functional outcomes.
Correlation between metal-metal distances and optical spectroscopy in the platinum blues: synthesis, crystal structure, and electronic spectrum of ethylenediamine platinum .alpha.-pyridone blue

Etude par diffraction RX du complexe [Pt 4 (H 2 NCH 2 CH 2 CH 2 NH 2 ) 4 (C 5 H 4 NO) 4 ](NO 3 ) 5 •H 2 O. Cristallisation dans le systeme triclinique, groupe P1 et affinement jusqu'a R=0,03
Changes and significance of plasma coupling factor 6 in patients with congenital heart disease with severe pulmonary hypertension

目的 研究血浆偶联因子6(CF6)在先天性心脏病(CHD)并重度肺动脉高压(PAH)患儿中的变化及意义。 方法 选取2014年1月至2015年1月在开封儿童医院就诊的CHD患儿155例，根据合并PAH情况将患儿分为3组：CHD未合并PAH患儿40例为无PAH组，CHD合并轻中度PAH患儿73例为轻中度PAH组，CHD合并重度PAH患儿42例为重度PAH组。采用放射免疫法对3组患儿血浆中CF6水平进行检测，分析CF6水平与PAH程度的相关性。 结果 无PAH组、轻中度PAH组、重度PAH组术前CF6水平分别为(189.6±43.2) ng/L、(169.5±87.1) ng/L、(303.1±80.5) ng/L，重度PAH组CF6水平较无PAH组、轻中度PAH组明显升高(P均<0.01)。术后1 d，重度PAH组血浆CF6水平与轻中度PAH组、无PAH组比较差异有统计学意义(P均<0.05)；术后3、7、14、28 d，重度PAH组血浆CF6水平与无PAH组比较差异均有统计学意义(P均<0.05)。重度PAH患儿肺动脉收缩压/血压收缩压比值与血浆CF6水平呈正相关(r＝0.658，P<0.01)。 结论 CHD合并PAH患儿血浆CF6水平升高，且升高水平与PAH程度呈正相关，提示其可能是重度PAH形成的重要因素之一，可将其作为治疗CHD合并重度PAH儿童的无创指标。
Zygomaticomaxillary Complex Fractures

The zygomaticomaxillary complex (ZMC) is an essential anatomic and functional element of the aesthetic facial skeleton. It plays a key role in the structure, function, and aesthetic appearance of the facial skeleton. It provides normal cheek contour and separates the orbital contents from the temporal fossa and the maxillary sinus. Zygomaticomaxillary complex provides a key structural support to the orbit. Disruption in the anatomic location may result in a change in globe position resulting in enophthalmos, globe dystopia, as well as diplopia. The zygoma is the origin for the masseter and therefore affecting mastication. The bones of the ZMC create the inferior and lateral orbital socket thus potentially affecting the correct position of the globe and mobility of the extraocular muscles.
Season, Classifier, and Spatial Resolution Impact Honey Mesquite and Yellow Bluestem Detection using an Unmanned Aerial System

Abstract In Texas, mesquite and yellow-bluestem invasions are widespread. Identifying and monitoring juvenile and adult plants using high-resolution imagery from airborne sensors while they colonize new areas across the landscape can help land managers prioritize locations for treatment and eradication. In this study, we evaluated how data collection design using an unmanned aerial system (UAS) can affect plant detection and mapping. We used a Phantom 3 Professional unmanned aerial vehicle with a Parrot Sequoia multispectral camera for detecting and mapping native honey mesquite (Prosopis glandulosa) and non-native yellow bluestem (Bothriochloa ischaemum) at a rangeland site in northwest Texas. Flights were conducted seasonally during the period from summer 2017 to fall 2018 to test the seasonal impact of detecting plant species. Flights were conducted at altitudes of 30, 60, and 100 m, and four image classification techniques were tested to determine their viability of detecting distinct plant species. Results suggest that flights at 100-m aircraft altitude during the spring season are more effective (>80% user accuracies) for mapping mesquite canopies based on reflectance values and image segmentation information. Yellow bluestem mapping accuracies were low (