cssi/SciSciGPT-SciSciNet huggingface dataset:
Neural fibrolipoma of the foot

Neural fibrolipoma is a benign tumor comprised of hypertrophied fibrofatty tissue with intermixed nerve tissue. We present the case of a neural fibrolipoma of the foot that underwent above-ankle amputation and review the characteristic features of this unique form of localized gigantism.
Effect of noise on hearing and cardiovascular system of attendant in generator car of train

[Objective]To understand the effect of noise on hearing and cardiovascular system of generator car attendant.[Methods]Blood pressure,electrocardiogram,pure tone air conduction hearing threshold examination were performed on 272 generation car attendants.[Results] The detection rate of normal blood pressure,high limit,hypertension was 21.7%,55.9%,22.4%.Abnormal electrocardiogram were mainly manifested as rhythm changes,high voltage of left ventricular and left axis deviation,ST segment and T wave abnormality.Pure tone air conduction hearing threshold examination showed the detection rate of binaural high frequency average hearing threshold greater than 40 dB of attendants with noise exposure length of 10-19 years(12.6%) was higher than that of attendants with noise exposure length 10 years(3.4%),the difference was significant(χ2= 5.71,P 0.05).The detection rate of the binaural high frequency average hearing threshold between 26-39 dB was 18.3%.And the detection rates of binaural high frequency average hearing threshold between 26-39 dB of attendants with noise exposure length of 10-19 years(22.5%) and≥20 years(29.4%) were significantly higher than that of attendants with exposure length 10 years(9.0%),the differences were significant(χ2= 7.13,χ2= 5.53,P 0.01,P 0.05).reasing of noise exposure length.The phenomenon of high normal blood pressure and high detection rate of pure tone hearing threshold between 26-39 dB should attract attentions Active efforts should be made on the sound insulation and noise reduction,reasonable arrangements for work and rest time.
Separation of Enantiomers of Nateglinide by RP-HPLC with Chiral Mobile Phase Additives

A RP-HPLC method with chiral mobile phase additives was established for separation of enantiomers of nateglinide. A C18 column was used, with the mobile phase of acetonitrile-water (25∶75,aqueous solution containing 1mmol/L L-proline, 0.5mmol/L cupric acetate and 30mmol/L sodium acetate), at the UV detection wavelength of 210nm. The calibration curves of nateglinide and its L-isomer were linear in the range of 5 - 150μg/ml. The detection limit was 0.5μg/ml.
Interventional cardiology--an overview.

Unt i l 10 years ago, cardiac catheterization was predominantly a diagnostic tool for defining anatomic and functional disease states before cardiac surgical correction. After a decade of tentative exploration with the fixed rigid dilator technique of Dotter, balloon dilatation was developed by Andreas Gruentig in 1974 as a treatment for peripheral atherosclerotic stenosis, ushering in the new field of "interventional cardiology." The current supplement to the American Journal of Cardiology is based on a symposium that was sponsored by Advanced Cardiovascular Systems in June 1987 to assess the status of this important new field in which the cardiac catheter is used to render definitive treatment of cardiovascular disease, as well as to provide diagnostic data. The centerpiece of interventional cardiology today is percutaneous transluminal coronary angioplasty (PTCA). During the early years of PTCA (1977 through 1981), relatively crude devices and inexperienced operators limited PTCA to patients with proximal, discrete, subtotal stenosis of a single coronary artery (who comprised only 5 to 10% of the population requiring coronary revascularization), and to a primary success rate of only 60%. In contrast, coronary angioplasty is now being applied routinely to patients with more complex coronary anatomic situations, including distal disease, stenosis of multiple vessels, bifurcation lesions, total occlusions, and diseased saphenous vein or internal mammary artery bypass grafts. Concomitant with this expansion in the anatomic capabilities of coronary angioplasty has been a marked broadening of its clinical indications, which now include patients with chronic stable angina, unstable angina, acute myocardial infarction, clinical features that make bypass surgery unacceptable, and a small subgroup of
Aeroelastic Model for Macrofiber Composite Actuators on Micro Air Vehicles

The main focus of this research is the generation of a computational aeroelastic model for a macrofiber composite actuated micro air vehicle. Two M8528-P1 actuators were used to deform the surface of a forward-swept thin, compliant composite wing. The general approach, which included MATLAB, ABAQUS, and Athena Vortex Lattice, is described. The planform design and initial flight testing are discussed. The computational model was validated first with static tests, and then quasi-static wind-tunnel tests were used to validate the aeroelastic model. Digital image correlation was used to compare the expected and measured displacements of the wing. Flight loads were also compared for various angles of attack. The results indicated good agreement for angles of attack well within the standard flight envelope, despite small discrepancies in geometry.
A General, Full-Wave Approach for Modeling Signal Lines and Discontinuities in Computer Packages

A full-wave moment-method approach is presented for obtaining the electrical characteristics of the 3D signal line and discontinuity structures typically found in computer packages. Rooftop current elements are used to represent both the surface current on conductors and the polarization current in any dielectric regions that may be present. The approach is applied to the computer module used in the IBM 3090 processor unit. The propagation characteristics of signal lines and vias, and coupled noise between signal lines are calculated and compared to results obtained from scale models and specifically designed test vehicles. The approach is then applied to representative, non-TEM waveguide structures that may appear in other package-related environments.
Are colorimetric assays appropriate for measuring phenol oxidase activity in peat soils

The activity of extracellular phenol oxidases is believed to play a critical role in decomposition processes in peatlands. The water logged, acidic conditions, and recalcitrant litter from the peatland vegetation, lead to exceptionally high phenolics in the peat. In order to quantify the activity of oxidative enzymes involved in the modification and break down of phenolic compounds two types of assays are primarily utilized: L-DOPA and ABTS. This note focuses on the strengths and weaknesses of both approaches. Both assays involve a redox reaction and the resulting oxidized chromophore is measured spectrophotometrically. However, in the presence of reducing agents such as the phenolics commonly found in peat the colorimetric reaction is reversed and cannot be used to quantify phenol oxidase activity.
Effects of highway pollution on forest lichen community structure in western Wake County, North Carolina, U.S.A.

Abstract We studied lichen communities along forest edge-to-interior gradients on opposite sides of a major highway and along a remote lakeshore in central North Carolina, U.S.A., to investigate highway pollution effects on this sensitive ecosystem component. At each site we sampled lichens on trees at 10 m intervals along each of five parallel transects established at the forest edge and at 25, 60, 100, and 150 m into the forest in the highway sites, with a similar layout along a nonlinear lakeshore in a similar forest type, from which transect distances from the forest edge were estimated using average tree distances from the nearest shoreline. Lichen communities were inventoried on tree trunks from the base up to 1.5 m height, then compared both among and within sites. Species richness was highest in the control site, and did not differ between the two highway sites. The highway sites were more similar to one another than either was to the control site, based on Bray-Curtis similarity indices. No assoc...
Factors Affecting the Financial Management Systems Effectiveness: A Survey of Health Oriented Civil Society Organizations in Kenya

Purpose: The purpose of the study was to identify the factors affecting the financial management systems effectiveness in Kenyan health oriented civil society organizations.Materials and methods: The study was conducted through a cross sectional descriptive survey. The target population of the study was 1065 Nongovernmental organizations in Kenya. The accessible population refers to the 606 Nongovernmental organizations located in Nairobi County. A sample of 10% equivalent to 61 Nongovernmental organizations was selected from the Nongovernmental organizations located in Nairobi County. The respondents were financial managers in every selected Nongovernmental organization. Data was collected by use of a questionnaire and was analyzed by use of inferential and descriptive statistics. Descriptive statistics included frequencies and means. Inferential statistics included correlation, regression and ANOVA analysis. The tool for data analysis was the Statistical Package for Social Sciences (SPSS) version 20. The results were presented using tables and pie charts.Results: The study results indicated that information technology management in Nongovernmental organizations are reliable and flexible enough to support the financial management of the organization. Additional results indicated that Nongovernmental organizations had invested in a management information system which had lowered administrative costs. The usage of IT led to efficient management of processes of budget accounting. The findings imply that information technology has significant positive effect on financial management system.Recommendations: The study provided recommendations to the NGOs and other organization that ICT development should be maximized fully in the organization especially if the objective is to improve efficiency and financial management systems effectiveness. Human resource management must be fully functional in a company with continuous training of the staff to ensure up to date competences and increased knowledge in financial management. Further recommendations to the organization is to ensure that financial governance ought to be thorough throughout the company with sound rules and regulations that govern the accounting and financial sector of the organization. This will ensure timely and accurate disclosure of all financial matters regarding the corporation to the regulatory body thus showing the efficiency in financial management systems.
Tracking the Catalytic Cycle of Adenylate Kinase by Ultraviolet Photodissociation Mass Spectrometry

The complex interplay of dynamic protein plasticity and specific side-chain interactions with substrate molecules that allows enzymes to catalyze reactions has yet to be fully unraveled. Top-down ultraviolet photodissociation (UVPD) mass spectrometry is used to track snapshots of conformational fluctuations in the phosphotransferase adenylate kinase (AK) throughout its active reaction cycle by characterization of complexes containing AK and each of four different adenosine phosphate ligands. Variations in efficiencies of UVPD backbone cleavages were consistently observed for three α-helices and the adenosine binding regions for AK complexes representing different steps of the catalytic cycle, implying that these stretches of the protein sample various structural microstates as the enzyme undergoes global open-to-closed transitions. Focusing on the conformational impact of recruiting or releasing the Mg2+ cofactor highlights two loop regions for which fragmentation increases upon UVPD, signaling an increas...
Seasonal variation in root growth of three grass species under varying cutting treatments

There are few data describing full seasonal variations in root mass fluctuations of perennial grasses. This experiment documented the seasonal changes in root weight density of three grass species under different management regimes. Kentucky bluegrass (Poa pratensis L.) and tall fescue (Festuca arundinacea Schreb.) received one annual cut, twice yearly forage harvest, and mown turf treatments. Orchardgrass (Dactylis glomerata L.) received one or two yearly cutting treatments. Soil cores were collected to a 15-cm depth and divided into two 7.5-cm increments. Roots and mat were recovered from the cores, washed, dried and weighed. Differences in year, season, and soil depth significantly influenced root weight density. Mean seasonal root weight densities in the top 7.5 cm during the cool, wet growing season of 1992 were 4.81,4.36, and 3.67 mg cm-3 in spring, summer, and fall, respectively. In the lower 7.5-cm horizon the mean root weight densities were 1.38,1.28, and 0.93 mg cm-3. Mean seasonal root densities in the top 7.5 cm for the hotter, drier season of 1993 were 3.25,2.74, and 2.71 mg cm-3 for spring, summer, and fall, respectively. In the deeper horizon the mean root densities were 0.99, 0.95, and 0.93 mg cm-3. Root weight density differences attributable to grass species and cutting treatments were also significant. Differences among seasons, grass species, and cutting treatments significantly influenced mat weight density. Mean mat densities for combined species and treatments were 66.8, 53.3 and 71.6 mg cm-3 for spring, summer, and fall, respectively. In all species and treatments, new root growth was heavy in spring and ceased at the beginning of summer, with the lowest root weight densities occurring in late August. The less frequently cut grasses resumed new growth earlier in the fall than did regularly mown turf. An awareness of the seasonal fluctuations in root growth is necessary when researching or managing the rhizosphere. The quantity of roots present, cycles of growth and senescence, and subsequent root interaction with soil micro-organisms all exhibit seasonal differences with unique environmental consequences.
Grid Generation About High-Lift Wing Configurations

The current guidelines provided by the 3rd AIAA CFD High Lift Prediction Workshop for building unstructured meshes representing high-lift wing configurations are demonstrated and discussed. Specifically, Pointwise grid generation software is used to generate general multi-element unstructured grids about the NASA High Lift Common Research Model and the Japanese Aerospace Exploration Agency Standard Model with and without nacelles and pylons. Several modifications to the guidelines that enhance grid quality are presented. Additionally, the user-defined parameters within Pointwise that govern the mesh generation process are reviewed in detail.
A Quasiparticle Transport Explanation for Collectivity in the Smallest of Collision Systems (p + p and e+e−)

Abstract The field of heavy ion physics is at a crossroads in understanding experimental signatures of collectivity in small collision systems, p + p and p ( d , 3 He)+A, at RHIC and the LHC. A wealth of data obtained in the latter class of asymmetric systems indicate the existence of particle emission patterns similar to those observed in larger A+A collisions [J. L. Nagle, W. A. Zajc, Small System Collectivity in Relativistic Hadron and Nuclear Collisions, arXiv:1801.03477 ]. This raises the question whether the same physics is responsible for these signatures in both small and large collision systems. In this talk, we present an extension of earlier studies using the quasiparticle transport model ampt to predict particle emission patterns in the smallest of collision systems, namely p + p and e + e − . The e + e − results have been previously published [ J. L. Nagle, R. Belmont, K. Hill, J. Orjuela Koop, D. V. Perepelitsa, P. Yin, Z.-W. Lin, D. McGlinchey, Minimal conditions for collectivity in e + e − and p + p collisions, Phys. Rev. C97 (2) (2018) 024909. arXiv:1707.02307 , doi: 10.1103/PhysRevC.97.024909 ] and we thus focus here on an extended set of calculations, as shown at the Quark Matter 2018 Conference.
Immune and Autoimmune Reactions in the Pathogenesis of Slow Virus Disease

The slow virus diseases are a fascinating example of an immunological enigma which may be at the center of the mechanism of slow virus disease pathogenesis. Studies on lymphocytic choriomeningitis (LCM) virus infection in mice showed that animals which had been inoculated at birth could suffer from a long continued infection with high titers of virus (Hotchin 1961, 1962). This “persistent tolerant infection” (PTI) (Hotchin and Weigand, 1961) was found to lead, after approximately 10 months, to a debilitating fatal disease (Hotchin, 1962; Hotchin and Collins, 1964). A brief look at this situation with LCM will introduce the main subject of my discussion.
Oxygen, Carbon Dioxide, and Ascorbic Acid

Oxygen contact with must and wine is a concern to the winemaker throughout the winemaking process. In some instances (e.g., in juice processing, during barrel aging, etc.), selected and controlled exposure to oxygen may play an important and beneficial role in wine quality. In situations such as bottling, oxygen levels should be as low as possible to prevent premature deterioration.
Reading Cultural Studies of Medicine

This article introduces cultural studies of medicine to medical humanities readers. Rather than offer extended definitions of cultural studies of medicine or provide a detailed history of the domain, I have organized this introduction around a close reading and review of three recently published texts in the field. These three texts, dealing respectively with “cyborg” technology, AIDS, and the medical “management” of sexual identity problems, represent excellent examples of the opportunities and possibilities of applying cultural studies approaches to medical topics. After working through these texts (and the semiotic “theories” which animate them), I devote my conclusion to a broader consideration of the role of cultural studies of medicine for both medical practice and medical humanities scholarship.
Two New Natural Enemies of Western Flower Thrips in California

An entomophilic nematode, Thripinema nicklewoodii (Tylenchida: Allantonematidae) and an endoparasitic wasp, Ceranisus sp. (Hymenoptera: Eulophidae) were recently recovered from western flower thrips (WFT) in California. Observations suggest nematode transmission into WFT occurs while the thrips feed on the plant. Females parasitized by the nematode appear to be reproductively sterile. The parasitic wasp was collected in samples of thrips-infested alfalfa and garden roses. Under laboratory conditions it predominantly oviposited into first instars, resulting in WFT death at the pre-pupal stage. Host-feeding was common. Identification of the wasp to the species level remains undetermined.
Perioperative Considerations in Pharmacology

Although anesthesiologists are adept at caring for the perioperative patient and the many physiologic aberrations resulting from surgery and anesthesia, management of perioperative pharmacology presents its own diverse set of challenges. Pharmacologic considerations for the perioperative period include the impact of (1) variable responses based on the patient’s genotype and/or phenotype, (2) preexisting diseases and drug therapies, (3) interactions with herbal supplementation, and (4) the physiologic changes associated with anesthesia. Many surgical patients are on chronic medications for comorbidities unrelated to the diagnosis that brought them to the OR. Anesthesiologists must be aware of both the effects of withdrawing chronic medications and the potential for interactions between “home” medications and the many drugs administered during the perioperative period. In addition to pharmacologic interactions, patient-specific factors like weight and genetic makeup will also impact the anesthetic plan. This chapter will discuss these factors, as well as anesthetic implications of commonly used medications, including herbal supplements. The side effects of nicotine and other aspects of cigarette smoking will also be discussed due to its prevalence and important anesthetic implications. Finally, the impact of anesthesia and surgery on human physiology and subsequent effects on drug metabolism will be reviewed.
Grandparents of Children With Intellectual and Developmental Disabilities: Navigating Roles and Relationships

Grandparents can play critical roles in the lives of children with intellectual and developmental disabilities and their families. However, current research and understanding around grandparent roles and experiences is limited. The purpose of this qualitative study was to examine the roles and experiences of grandparents supporting children with disabilities. In this article, the voices of grandparents with diverse experiences are presented. Key themes that emerged were the role of the grandparent, boundaries in roles and space, navigating family dynamics, and the general experiences of grandparenting. These findings have implications for the types of supports provided to grandparents and for practitioners working with families who have actively involved grandparents.
Mindfulness-Based Childbirth and Parenting: Cultivating Inner Resources for the Transition to Parenthood and Beyond

Mindfulness-based childbirth and parenting (MBCP) is a formal adaptation of mindfulness-based stress reduction (MBSR; 1982, 1990). Its goal is to promote the physical and mental health of expectant parents during a normative developmental transition. Over the course of 10 sessions during the second half of pregnancy, women and their partners are taught mindfulness skills for working with the stress, pain, and fear that may accompany this transition. Preliminary research shows that participants show significant reductions in depressive mood and pregnancy-related anxiety and increases in positive emotions. They also report using the mindfulness skills taught in MBCP to cope with stressful aspects of the pregnancy, the birth process, and the early period of parenting. This chapter describes the theoretical foundations for MBCP and the structure and content of the program. A case study illustrates the nature of the program and its benefits, and the empirical evidence of its efficacy is reviewed.
The Dold–Thom theorem via factorization homology

We give a new proof of the classical Dold–Thom theorem using factorization homology. Our method is direct and conceptual, avoiding the Eilenberg–Steenrod axioms entirely in favor of a more general geometric argument.
Attacklets: Modeling High Dimensionality in Real World Cyberattacks

We introduce attacklets, a novel approach to model the high dimensional interactions in cyberattacks. Attacklets are implemented using a real-world dataset of cyberattacks from the Verizon Data Breach Investigation Report. Whereas the commonly used attack graphs model the action sequences of attackers for specific exploits, attacklets model general attributes and states of each attack separately. Attacklets may inform the number and types of attributes across a wide range of cyberattacks. These structural properties can then be used in machine learning models to classify and predict future cyberattacks.
Quantifying Water Balance Components at a Permeable Pavement Site Using a Coupled Groundwater–Surface Water Model

AbstractGreen infrastructure (GI) is being widely implemented in urban areas to capture and remove stormwater from the surface drainage system. Whereas most analyses have focused on diverted surfac...
Creating an Innovation Environment for Developing and Testing Surgical Devices within an Academic Medical Center

Being a medical device innovator is highly rewarding because you can impact human health, while being fully intellectually engaged and stimulated. Developing a new medical device for surgery requires more than a good idea and sound engineering. Successful innovators need a nurturing environment, as well as training and knowledge in a range of associated topics including: (1) the innovation process; (2) identification and definition of clinical needs; (3) device prototyping and testing; (4) preclinical and clinical research; (5) regulatory and reimbursement issues; (6) intellectual property; and (7) business development fundamentals. One must be a lifelong student of medical device innovation because the innovation process continuously evolves. For example, 3D printing, digital simulation, and immersive visualization are currently transforming how devices are prototyped. In addition, combination device and drug therapies are changing how medical technologies are regulated, and the field of health informatics is leveraging the explosion of medical data to drive clinical and reimbursement decisions. This chapter discusses the University of Minnesota’s unique and long-standing innovation environment for new and experienced medical device innovators, an environment that includes courses, training programs, conferences, workshops, the Earl E. Bakken Medical Device Center, the Institute for Engineering in Medicine, and numerous laboratories within their Department of Surgery.
Children’s implicit attitude acquisition: Evaluative statements succeed, repeated pairings fail

From the earliest ages tested, children and adults show similar overall magnitudes of implicit attitudes toward various social groups. However, such consistency in attitude magnitude may obscure meaningful age-related change in the ways that children (vs. adults) acquire implicit attitudes. This experiment investigated children's implicit attitude acquisition by comparing the separate and joint effects of two learning interventions, previously shown to form implicit attitudes in adults. Children (N = 280, ages 7-11 years) were taught about novel social groups through either evaluative statements (ES; auditorily presented verbal statements such as 'Longfaces are bad, Squarefaces are good'), repeated evaluative pairings (REP; visual pairings of Longface/Squareface group members with valenced images such as a puppy or snake), or a combination of ES+REP. Results showed that children acquired implicit attitudes following ES and ES+REP, with REP providing no additional learning beyond ES alone. Moreover, children did not acquire implicit attitudes in four variations of REP, each designed to facilitate learning by systematically increasing verbal scaffolding to specify (a) the learning goal, (b) the valence of the unconditioned stimuli, and (c) the group categories of the conditioned stimuli. These findings underscore the early-emerging role of verbal statements in children's implicit attitude acquisition, as well as a possible age-related limit in children's acquisition of novel implicit attitudes from repeated pairings.
Multi-attribute analysis of benefit managers' preferences for smoking cessation programs.

This article reports the results of formative research on worksite benefit managers' preferences for smoking cessation programs. Procedures focused on application of a multi-attribute preference evaluation method known as conjoint analysis. Literature reviews, small-sample telephone interviews, and a focus group were used to guide selection of cessation program attributes for this analysis. Personnel benefit managers representing a variety of worksites (N = 103) across the U.S. were then randomly selected for participation in the study. Results suggested that cost per employee, program management options, success rates, and endorsements were associated with relatively higher utility values, as compared with attributes concerning program materials or content (e.g., emphasis on cessation preparation vs. maintenance techniques). Benefit manager response simulations indicated a low-cost program with flexible delivery options received the strongest overall response of the six types of programs tested. Results also suggested there were preference differences associated with the type of worksite. Implications of these results for future study are briefly discussed.
Abstract 126: ’Tick Tock’ it’s Time to Shock; Increased Shock Latency is Associated With Intra-Arrest Transport and Reduced Survival From Out-Of-Hospital Cardiac Arrest

Introduction: Timely defibrillation of shockable rhythms during out of hospital cardiac arrest (OHCA) is an important link in the chain of survival. In 2011 the Salt Lake City Fire Department (SLCF...
Ovarian Stimulation Is Safe and Effective for Patients with Gynecologic Cancer

Purpose: To compare long-term outcomes of gynecologic cancer patients who pursued controlled ovarian hyperstimulation (COH) for fertility preservation (FP) with those who did not. Methods: Retrospe...
Prion protein — mediator of toxicity in multiple proteinopathies

A new study shows that interactions of the cellular prion protein with amyloid-β, tau and α-synuclein oligomers are important in mediating the toxicity of these proteins in Alzheimer disease and Parkinson disease. The findings suggest a shared pathway that could be a therapeutic target common to multiple neurodegenerative diseases.
Using Prescriptive Data Analytics to Reduce Grading Bias and Foster Student Success

This innovative practice work-in-progress paper presents our approach of using data analytics as an alternative solution to eliminate grading bias. Effective grading involves maintaining consistency among all students, irrespective of gender, race, ethnic background, and prior performance. Related work in this area has shown that prior work submitted by a student influences future scores given. Some of the popular methods used to eliminate grading bias involves grading rubrics, anonymous or blind grading, and/or computerized auto-graders. In spite of all these methods, some types of grading such as essays and projects still require subjective grading, which opens the door to conscious or unconscious bias.Given the student data available regarding performance, colleges and universities are turning to analytic solutions to extract meaning from huge volumes of student data to help improve retention, graduation, and student performance rates. While looking at all the analytic options can be a daunting task, these analytic options can be categorized at a high level into three distinct types: (a) Descriptive Analytics, which use data aggregation and data mining to provide insight into the past and answer “What has happened?”; (b) Predictive Analytics, which use statistical models and forecasts techniques to understand the future and answer “What could happen?”; and (c) Prescriptive Analytics, which use optimization and simulation algorithms to advise on possible outcomes and answer “What should we do?” In this paper, we use Prescriptive Analytics to provide students with advice on what action to take, based on a tool which predicts each student’s performance.
Chapter 5 – Hilbert Spaces

In this chapter, general concepts connected with inner product spaces are presented. After introducing the axioms of an inner product space, a number of specific examples are given, including both familiar cases of Euclidean spaces, and a number of function spaces which are extensively used in the remainder of the book. The important case of a Hilbert space, when the space is complete with respect to the given norm arising from the inner product, receives special attention. Orthogonality, projections, and the characterization of an orthonormal basis of a Hilbert space are discussed and studied in some detail. The standard isomorphisms between a separable Hilbert space and either its dual space, or a suitable sequence space are presented.
NQO1 C609T gene polymorphism associated with an increased risk of post operative cognitive dysfunction

Objective To investigate the association between the C609T polymorphism of NAD (P)H:quinoneoxidoreductase (NQO1) gene and post operative cognitive dysfunction (POCD).Methods 90 ASA Ⅰ-Ⅱ patients of 59 to 78 years old, undergoing elective hip replacement with epidural anesthesia were enrolled.All patients were given a battery of 5 neuropsychological tests before operation and seven days after operation.Patients were divided into POCD group and control group according to test results (45 patients in each group).The single nucleotide polymorphism C609T of NQO1 gene was detected using real-time PCR by Taqman probes and subjected to odd ratio assessment.Results 5 samples in control group couldn' t be used in the real-time PCR analysis due to quality control.The frequency of C/C genotype in POCD control was lower than that of control group ( 30.0% vs 11.1% ) with statistical significance ( OR = 0.292,95 % CI 0.092 ～ 0.92 1, P ＜ 0.05 ).The C/T +T/T genotype frequency was significantly higher in group POCD than in the control group(88.8% vs 70% ).Patients presented with C/T + T/T genotype showed an evidently increased risk of POCD ( OR =3.42,95% CI 1.08 ～ 10.82,P ＜ 0.05 ).The frequency of C allele of NQO1 gene in group control was 56.2%, as compared with 40% in group POCD with significance ( OR = 0.519,95% CI 0.282 ～ 0.955, P ＜ 0.05 ).The frequency of T allele of NQOI gene in control group was 43.7% ,as compared with 60.0% in POCD group( OR = 1.93,95% CI 1.047 ～3.552,P＜O.05).Conclusion The NQO1 gene single nucleotide polymorphism C609T is evidently associated with the increased risk of POCD. Key words: Post operative cognitive dysfunction; NADPH oxidoreductases; Single nucleotide polymorphism
A Diﬀusion Approximation Framework for Ride-Hailing with Travel Delays

This paper develops a closed queueing network model of a ride-hailing system by viewing cars as the jobs moving through various nodes of the network perpetually. The queueing network model crucially incorporates the travel times between diﬀerent nodes of the network. We prove a novel heavy-traffic limit theorem for this queueing network, providing an approximation for the original ride-hailing system.
Amplifying the Theory of Planned behavior with connectedness to water to inform impactful water conservation program planning and evaluation

The purpose was to examine whether connectedness to water could improve the predictive power of the Theory of Planned Behavior on outdoor water conservation intentions. We adapted the well-establis...
Assessing surface air pressure sensing using 118 GHz O2-absorption radar system

Abstract This study assesses surface air pressure remote sensing using a differential absorption radar at the 118 GHz O2 line. The considered system would have, at least two, closely-spaced frequency channels. Environmental impacts like surface reflections and absorptions from water vapor and other gases, and liquid water clouds on the radar signals of these channels are very similar, but the difference in O2 absorption is substantial. The surface pressure could be retrieved from the radar measured differential absorption optical depth of the atmosphere. The operational frequencies of the radar system are optimally selected, and the transmitted powers of the paired stronger and weaker O2 absorption channels are carefully distributed to balance the signal-to-noise ratios of these channels. Simulations of radar signals and pressure retrievals show that with an airborne system cruising at 10 km altitude, surface pressure measurements could achieve 1 mb accuracy within 1-s data processing. These pressure measurements would provide urgently needed supports in improving severe and general weather forecasts and gain unique knowledge on planetary boundary layer meteorology. Other advantages of this kind of high frequency radars would be their higher spatial resolution and increased potentials of small- or CubeSat applications.
Global Pandemic: Business Model Impact on Enterprises reTHINK, reIMAGINE, reINVENT Businesses

The COVID-19 outbreak is a sharp reminder that pandemics, like other rarely occurring catastrophes, have happened in the past and will continue to happen in the future. Even if we cannot prevent dangerous catastrophes, businesses need to manage risks, reduce costs, improve efficiency while digitizing products and offerings, streamlining processes to retain existing customers. As industry leaders around the globe are driving their teams forward from their attics, basements and spare rooms, the need for business continuity is vital more than ever. It is important for Enterprises to have the right tools, technology and skills to deal with this crisis. One can make use of expert advice through consulting services to understand the level of preparedness and to respond quickly with what needs to be done. It is time to quickly move beyond manual, people-dependent processes and switch to automation and orchestration to reduce the complexity. Our solution takes advantage of modeling in over 80 different types of industries and addresses both industry standard as well as custom priorities to help enterprises focus on the right investment to improve the performance of their business components.
Sociometry and Social Work Theory

The congruence of sociometry theory and social work theories is covered in detail in this chapter. The social atom, cultural atom, and sociogram are described with visual depictions. Moreno’s theories of interpersonal connection, social networks, and society are depicted while introducing sociometry terms such as the sociodynamic effect, tele, and the organic unity of mankind. Sociometry’s connection to social work’s person-in-environment theories is emphasized while also considering the shared concern for how social forces impact individuals and groups.
Online Appendix: The Time-Varying Diversifiability of Corporate Foreign Exchange Exposure

This appendix presents additional tables for “The Time-Varying Diversifiability of Corporate Foreign Exchange Exposure.”
A Benchmark to Test Generalization Capabilities of Deep Learning Methods to Classify Severe Convective Storms in a Changing Climate

This is a test-case study assessing the ability of deep learning methods to generalize to a future climate (end of 21st century) when trained to classify thunderstorms in model output representativ...
Photoreceptor Cell Calcium Dysregulation and Calpain Activation Promote Pathogenic Photoreceptor Oxidative Stress and Inflammation in Prodromal Diabetic Retinopathy

This study tested the hypothesis that diabetes promotes a greater than normal cytosolic calcium level in rod cells that activates a Ca2+-sensitive protease, calpain, resulting in oxidative stress and inflammation, two pathogenic factors of early diabetic retinopathy. Nondiabetic and 2-month diabetic C57Bl/6J and calpain1 knockout (Capn1−/−) mice were studied; subgroups were treated with a calpain inhibitor (CI). Ca2+ content was measured in photoreceptors using Fura-2. Retinal calpain expression was studied by quantitative RT-PCR and immunohistochemistry. Superoxide and expression of inflammatory proteins were measured using published methods. Proteomic analysis was conducted on photoreceptors isolated from untreated diabetic mice or treated daily with CI for 2 months. Cytosolic Ca2+ content was increased twofold in photoreceptors of diabetic mice as compared with nondiabetic mice. Capn1 expression increased fivefold in photoreceptor outer segments of diabetic mice. Pharmacologic inhibition or genetic deletion of Capn1 significantly suppressed diabetes-induced oxidative stress and expression of proinflammatory proteins in retina. Proteomics identified a protein (WW domain-containing oxidoreductase [WWOX]) whose expression was significantly increased in photoreceptors from mice diabetic for 2 months and was inhibited with CI. Knockdown of Wwox using specific siRNA in vitro inhibited increase in superoxide caused by the high glucose. These results suggest that reducing Ca2+ accumulation, suppressing calpain activation, and/or reducing Wwox up-regulation are novel targets for treating early diabetic retinopathy.
Estimation of mean scatterer spacing based on autoregressive spectral analysis of pre-filtered echo data

Mean scatterer spacing (MSS) has been recognized as an effective tool for characterization and discrimination of tissues that present a semi-regular lattice of scatterers. The spectrum of the ultrasound echo of these tissues presents a number of harmonics due to the semi-regular scatterer distribution. A new algorithm for estimating the MSS by exploring the harmonic contents of the ultrasound echo is presented. This algorithm also provides a reliability indicator of the MSS estimate allowing for acceptance or rejection of the estimate. Simulations show that the acceptance criterion has been effective in reducing the standard deviation of the MSS estimates. In vitro experiments were conducted to illustrate the practical use of the proposed algorithm in the estimation of MSS.
Bilateral ovarian fibroma

Abstract Fibroma of both ovaries is reported in a 73-year-old white woman. The large growths appeared grossly almost alike and microscopically they mimicked ovarian stroma. They contained no epithelial elements. There was no associated ascites and hydrothorax.
Absence of Kondo lattice coherence effects in Ce0.6La0.4Pb3: A magnetic-field study

The specific heat of polycrystalline Ce0.6La0.4Pb3 has been measured in magnetic fields ranging from 0to14T. After subtraction of a lattice contribution, the specific heat between 1K and 10K is well described by the S=12 single-impurity Kondo model with just one adjustable parameter: the zero-field Kondo temperature. In particular, the variation in the temperature and the height of the peak in C vs T is captured with good accuracy. This fit suggests that lattice coherence effects play no significant role in the magnetic-field response of this concentrated Kondo system.
Neutron Radiography with SNRS

The Stationary Neutron Radiography System (SNRS) is a real-time neutron radiography system nearing completion at McClellan Air Force Base, Sacramento, CA. SNRS will be used for the inspection of F-111 aircraft components for corrosion. General Atomics is the prime contractor providing the TRIGA reactor and the building and SAIC is a subcontractor providing the robotics, image acquisition and analysis and part of the reactor shielding.
Electromagnetic Wave Interactions with Inhomogeneous Plasmas

Experimental observations of electromagnetic wave propagation and interactions with a large inhomogeneous laboratory plasma are summarized. The dominant process is the conversion of electromagnetic waves into electrostatic waves whose field strengths are enhanced by several orders of magnitude in the vicinity of the resonant layer where the incident frequency matches the local plasma frequency. Strong local accelerations of electrons and ions by these localized resonant fields are described. Density cavities produced by the digging actions of these ponderomotive forces are called “cavitons” which coexist with the rf fields. Parametric decay instabilities are found to be a much weaker process compared with the caviton formation at the resonant layer. A double resonance technique of controlling ion dynamics at a specific location in an inhomogeneous plasma is demonstrated. The correlations between the present experiments and laser-plasma interactions, as well as radio wave interactions with the ionosphere, are discussed.
Static and Moving Object Detection Using Flux Tensor with Split Gaussian Models

In this paper, we present a moving object detection system named Flux Tensor with Split Gaussian models (FTSG) that exploits the benefits of fusing a motion computation method based on spatio-temporal tensor formulation, a novel foreground and background modeling scheme, and a multi-cue appearance comparison. This hybrid system can handle challenges such as shadows, illumination changes, dynamic background, stopped and removed objects. Extensive testing performed on the CVPR 2014 Change Detection benchmark dataset shows that FTSG outperforms state-ofthe-art methods.
Pharmacologic stimulation of the nicotinic anti-inflammatory pathway modulates gut and lung injury after hypoxia-reoxygenation injury.

Purpose Pre-injury vagal nerve stimulation protects against gut and lung injury after experimental hemorrhagic shock (HS). This likely occurs via the cholinergic anti-inflammatory pathway and the α7 nicotinic acetylcholine receptor (α7nAChR). We hypothesized that, in an in vitro model, either nicotine or a selective α7nAChR agonist (AR-R17779) would modulate intestinal and pulmonary effects of gut ischemia-reperfusion after hypoxic insult. Methods Confluent HT29 intestinal epithelial cells were co-cultured with Escherichia coli. Cell cultures were subjected to 21% (control) or 5% O 2 (hypoxia) for 90 minutes followed by reoxygenation (H/R). HT29 cells were treated with nicotine or AR-R17779 before or immediately after hypoxic insult. From the HT29 cell culture supernatants, tumor necrosis factor-α and interleukin-6 levels were quantitated. Confluent pulmonary microvascular epithelial cells (HMVEC) were co-cultured with HT29 supernatants and permeability and intercellular adhesion molecule-1 expression were determined. Results In post H/R insult treatments with the receptor agonist, cytokine levels in HT29 cells were reduced to control levels. In HMVEC experiments, a protective effect was seen with treatment post H/R injury. Disruption of HT29 actin microfilaments was demonstrated after H/R insult and was abrogated by both agonists. Conclusion Post-insult pharmacologic stimulation seems to mimic the protective effects of pre-HS vagal nerve stimulation seen in animal studies.
A Case for Standards of Counseling Practice

A mature counseling profession has entered the decade of the 1990s. Several factors including professionalism, accountability, health care consumerism, credentialism, and public demands for quality mental health care indicate a need for more definitive statements on standards of practice in counseling. In response to this need, an 8-point proposal for standards of practice in mental health counseling is offered.
Down-regulation of intestinal apical calcium entry channel TRPV6 by ubiquitin E3 ligase Nedd4-2.

Nedd4-2 is an archetypal HECT ubiquitin E3 ligase that disposes target proteins for degradation. Because of the proven roles of Nedd4-2 in degradation of membrane proteins, such as epithelial Na+ channel, we examined the effect of Nedd4-2 on the apical Ca2+ channel TRPV6, which is involved in transcellular Ca2+ transport in the intestine using the Xenopus laevis oocyte system. We demonstrated that a significant amount of Nedd4-2 protein was distributed to the absorptive epithelial cells in ileum, cecum, and colon along with TRPV6. When co-expressed in oocytes, Nedd4-2 and, to a lesser extent, Nedd4 down-regulated the protein abundance and Ca2+ influx of TRPV6 and TRPV5, respectively. TRPV6 ubiquitination was increased, and its stability was decreased by Nedd4-2. The Nedd4-2 inhibitory effects on TRPV6 were partially blocked by proteasome inhibitor MG132 but not by the lysosome inhibitor chloroquine. The rate of TRPV6 internalization was not significantly altered by Nedd4-2. The HECT domain was essential to the inhibitory effect of Nedd4-2 on TRPV6 and to their association. The WW1 and WW2 domains interacted with TRPV6 terminal regions, and a disruption of the interactions by D204H and D376H mutations in the WW1 and WW2 domains increased TRPV6 ubiquitination and degradation. Thus, WW1 and WW2 may serve as a molecular switch to limit the ubiquitination of TRPV6 by the HECT domain. In conclusion, Nedd4-2 may regulate TRPV6 protein abundance in intestinal epithelia by controlling TRPV6 ubiquitination.
“No Worry Allowed. Get Out!” A Case Study Tribute to the Life and Work of Michael White

This paper gives one example of the application of ideas and practices from Narrative Therapy in three sessions of work with a family. This work was inspired by the early writing and workshop teachings of White (Fam Process 25:169–184, 1986, 1989) and Epston (Epston and White 1992; Freeman et al. in Playful approaches to serious problems. W.W. Norton, New York 1997). The skills of relative influencing questioning, externalizing the problem, noticing news of difference, raising dilemmas, discussing readiness for change, discovering unique outcomes, conversing with the problem and consulting your consultants were all applied to a presenting problem of extreme fear and worry. Excerpts from the transcription of the third and final session are included to demonstrate skills in the actual conversation with the family. Two-year and six-year follow up information is provided.