cssi/SciSciGPT-SciSciNet huggingface dataset:
Support for the file system security requirements of computational E-mail systems

Computational e-mail systems, which allow mail messages to contain command scripts that automatically execute upon receipt, can be used as a basis for building a variety of collaborative applications. However, their use also presents a serious security problem because a command script from a sender may access/modify receiver's private files or execute applications on receiver's behalf. Existing solutions to the problem either severely restrict I/O capability of scripts, limiting the range of applications that can be supported over computational e-mail, or permit all I/O to scripts, potentially compromising the security of the receiver's files. Our model, called the intersection model of security, permits I/O for e-mail from trusted senders but without compromising the security of private files. We describe two implementations of our security model: an interpreter-level implementation and an operating systems-level implementation. We discuss the tradeoffs between the two implementations and suggest directions for future work.
Functional Characterization of the Serine-Rich Tract of Varicella-Zoster Virus IE62.

ABSTRACT The immediate early 62 protein (IE62) of varicella-zoster virus (VZV), a major viral trans -activator, initiates the virus life cycle and is a key component of pathogenesis. The IE62 possesses several domains essential for trans -activation, including an acidic trans -activation domain (TAD), a serine-rich tract (SRT), and binding domains for USF, TFIIB, and TATA box binding protein (TBP). Transient-transfection assays showed that the VZV IE62 lacking the SRT trans -activated the early VZV ORF61 promoter at only 16% of the level of the full-length IE62. When the SRT of IE62 was replaced with the SRT of equine herpesvirus 1 (EHV-1) IEP, its trans -activation activity was completely restored. Herpes simplex virus 1 (HSV-1) ICP4 that lacks a TAD very weakly (1.5-fold) trans -activated the ORF61 promoter. An IE62 TAD-ICP4 chimeric protein exhibited trans -activation ability (10.2-fold), indicating that the IE62 TAD functions with the SRT of HSV-1 ICP4 to trans -activate viral promoters. When the serine and acidic residues of the SRT were replaced with Ala, Leu, and Gly, trans -activation activities of the modified IE62 proteins IE62-SRTΔSe and IE62-SRTΔAc were reduced to 46% and 29% of wild-type activity, respectively. Bimolecular complementation assays showed that the TAD of IE62, EHV-1 IEP, and HSV-1 VP16 interacted with Mediator 25 in human melanoma MeWo cells. The SRT of IE62 interacted with the nucleolar-ribosomal protein EAP, which resulted in the formation of globular structures within the nucleus. These results suggest that the SRT plays an important role in VZV viral gene expression and replication. IMPORTANCE The immediate early 62 protein (IE62) of varicella-zoster virus (VZV) is a major viral trans -activator and is essential for viral growth. Our data show that the serine-rich tract (SRT) of VZV IE62, which is well conserved within the alphaherpesviruses, is needed for trans -activation mediated by the acidic trans -activation domain (TAD). The TADs of IE62, EHV-1 IEP, and HSV-1 VP16 interacted with cellular Mediator 25 in bimolecular complementation assays. The interaction of the IE62 SRT with nucleolar-ribosomal protein EAP resulted in the formation of globular structures within the nucleus. Understanding the mechanisms by which the TAD and SRT of IE62 contribute to the function of this essential regulatory protein is important in understanding the gene program of this human pathogen.
Motivating technical professionals today

Having a highly motivated technical workforce is one of the key ingredients for fostering the innovative performance necessary for an organization to “stay in the game” in today's global competitiv...
Mercury Emission Monitoring for the Cement Industry

In March 2005, the U.S. Environmental Protection Agency (EPA) promulgated the Clean Air Mercury Rule (CAMR), the first rule ever to restrict mercury emissions from coal-fired power plants. Because the rule is designed to be a cap-and-trade program, mercury measurement is an important component. As a result, substantial effort and resources have been invested in developing mercury measurement protocols both in terms of continuous mercury measurement for compliance purposes and reference methods for conducting relative accuracy test audits (RATAs). Although utilities are the largest source of anthropogenic mercury, they are not the only source. EPA has announced mercury emission standards for new cement kilns but currently exempts existing facilities. Many states are also reviewing the potential of reducing mercury from other sources such as metals smelting, waste-to-energy facilities, and the cement industry. In the manufacture of cement, four raw materials are necessary: limestone, shale, clay, and iron slag. Of these four raw materials, three (limestone, shale, clay) are generally mined on-site, with only the iron slag being imported. To provide the energy required for the processing of the kiln feed in the pyroprocess, a typical plant can use coal, natural gas, used oil, tire-derived fuels, and/or other refuse-derived fuels. A potential source of mercury can be from either the raw materials or the fuel used during the cement- manufacturing process.
Evidence-Based Reading Instruction for Individuals with Autism Spectrum Disorders

Legislation mandates that all children, including children with autism spectrum disorders (ASD) be taught to read in ways that are consistent with reading research, and target the five components of evidence-based reading instruction: phonemic awareness, phonics, reading fluency, vocabulary and comprehension strategies. The purpose of this review is to synthesize the literature on reading instruction for children with ASD that encompasses one or more of the five components of reading. The review yielded 11 studies with 61 participants ages 4 to 17. Results indicate that children with ASD can benefit from reading instruction consistent with reading research. Research in this area is still preliminary, and more research is needed to guide practice. Possible directions for future research are provided.
TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and -independent pathways

TonEBP (tonicity-responsive enhancer binding protein) is a transcription factor that promotes cellular accumulation of organic osmolytes in the hypertonic renal medulla by stimulating expression of its target genes. Genetically modified animals with deficient TonEBP activity in the kidney suffer from severe medullary atrophy in association with cell death, demonstrating that TonEBP is essential for the survival of the renal medullary cells. Using both TonEBP knockout cells and RNA interference of TonEBP, we found that TonEBP promoted cellular adaptation to hypertonic stress. Microarray analyses revealed that the genetic response to hypertonicity was dominated by TonEBP in that expression of totally different sets of genes was increased by hypertonicity in those cells with TonEBP vs. those without TonEBP activity. Of over 100 potentially new TonEBP-regulated genes, we selected seven for further analyses and found that their expressions were all dependent on TonEBP. RNA interference experiments showed that some of these genes, asporin, insulin-like growth factor-binding protein-5 and -7, and an extracellular lysophospholipase D, plus heat shock protein 70, a known TonEBP target gene, contributed to the adaptation to hypertonicity without promoting organic osmolyte accumulation. We conclude that TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress in addition to organic osmolyte accumulation.
Broadband sampling oscilloscope characterization with the "nose-to-nose" calibration procedure: a theoretical analysis

In the past the "nose-to-nose" calibration procedure has been introduced as probably the most accurate method to determine the impulse response of broadband sampling oscilloscopes like the HP54124T (bandwidth exceeding 50 GHz). The method is based on the hypothesis that "sampler kick-out equals oscilloscope impulse response". This hypothesis was originally based on an intuitive approach and was later on verified experimentally as well as with SPICE simulations. Until now however there was no generalized mathematical evidence supporting this basic hypothesis. In this paper a mathematical theory is developed, which starts from a generalized sampler equivalent scheme, and which shows that, under conditions which are valid in practice, the sampler kick-out indeed equals the sampler impulse response. >
Congenital osseous rubella.

Two cases of congenital rubella are reported which showed bone changes. In one, the resemblance to congenital syphilis was remarkably close and in the other changes resembled Gaucher's disease. Previous descriptions of osseous congenital rubella have only noted metaphyseal changes and have not described abnormalities extending deeply into the shafts of the long bones. In view of the changing incidence of disease, the diagnosis of congenital rubella must now be suspected in infants showing bone abnormality, particularly with metaphyseal lesions otherwise resembling congenital syphilis.
Section 6. Oceanic Islands and the Deep Mantle

As I mentioned earlier, it now seems well established that most, although certainly not all, intraplate volcanism is a consequence of mantle plumes rising from the deep mantle, just as [Morgan (1971)][1] proposed. Morgan suggested these mantle plumes were analogous to atmospheric convection cells
Immunodeficiency viruses: the simian-human connection.

Presentation des donnees recentes concernant les retrovirus humains et simiens et plus particulierement les virus d'immunodeficience. Reflexion sur l'origine et la dissemination du virus HIV1
Measuring Interpersonal Communication

Measurement is a core activity and challenge in all social sciences, and the complex nature of interpersonal communication makes this fundamental activity particularly challenging. This entry provides a discussion of basic concepts in measurement and an introduction to the myriad considerations to be made in measuring constructs in interpersonal communication. It includes a review of the advantages and disadvantages of the most common techniques for measuring interpersonal communication, including observational assessments, self-reports, diaries and logs, and physiological assessments. In addition to the perennial challenges of measurement in interpersonal communication scholarship, this entry notes some of the promises and difficulties implicit in the rise of new communication technologies in interpersonal interaction. Keywords: cognitive processes; conflict; representation
Behavioral modification in a junior high learning disabilities classroom.

This study was conducted in the University of Washington Experimental Education Unit; subjects were 8 junior high age students admitted to the unit on the basis of having serious learning and behav...
Diminished circadian rhythms in hippocampal microglia may contribute to age-related neuroinflammatory sensitization

Abstract Aged animals exhibit diminished circadian rhythms, and both aging and circadian disruption sensitize neuroinflammatory responses. Microglia—the innate immune cell of the central nervous system—possess endogenous timekeeping mechanisms that regulate immune responses. Here, we explored whether aging is associated with disrupted diurnal rhythms in microglia and neuroinflammatory processes. First, hippocampal microglia isolated from young rats (4 months F344XBN) rhythmically expressed circadian clock genes, whereas microglia isolated from the hippocampus of aged rats (25 months) had aberrant Per1 and Per2 rhythms. Unstimulated microglia from young rats exhibited robust rhythms of TNFα and IL-1β mRNA expression, whereas those from aged rats had flattened and tonically elevated cytokine expression. Similarly, microglial activation markers were diurnally regulated in the hippocampus of young but not aged rats and diurnal differences in responsiveness to both ex vivo and in vivo inflammatory challenges were abolished in aged rats. Corticosterone is an entraining signal for extra–suprachiasmatic nucleus circadian rhythms. Here, corticosterone stimulation elicited similar Per1 induction in aged and young microglia. Overall, these results indicate that aging dysregulates circadian regulation of neuroinflammatory functions.
Amplitude and frequency modulation of the master laser in injection-locked laser systems

We explore the effects of modulating the master laser in injection-locked systems. We experimentally and theoretically discovered an intrinsic conversion of master FM into slave AM. We have modified the current theory to model the frequency response for residual amplitude modulation (RAM) suppression, FM efficiency, and FM-to-AM conversion.
New fit to the reaction γ p → K + Σ 0

The reaction $\ensuremath{\gamma}p\ensuremath{\rightarrow}{K}^{+}{\mathrm{\ensuremath{\Sigma}}}^{0}$ has been investigated using a tree-level effective Lagrangian model similar to that employed previously by the author to study the electromagnetic production of $\mathrm{\ensuremath{\Lambda}}$'s from protons. In addition to the Born terms, the model incorporates a number of baryon resonances with spins up to $\frac{5}{2}$ and the two kaon resonances, ${K}^{\ensuremath{\star}}(892)$ and $K1(1270)$. Momentum- and energy-dependent widths for the nucleon and $\mathrm{\ensuremath{\Delta}}$ resonances are included by means of a dynamical model that makes use of empirical on-shell branching ratios. The model parameters, consisting of products of the coupling strengths at the electromagnetic and strong interaction vertices in the resonance contributions, are fit to a large pool of photoproduction data from the CLAS and GRAAL Collaborations. Results are presented for the unpolarized differential cross section, the photon beam asymmetry $\mathrm{\ensuremath{\Sigma}}$, the hyperon recoil asymmetry $P$, and the double-polarization observables ${C}_{x}$ and ${C}_{z}$ in a variety of kinematical situations and compared with the data.
Esotericist Reading Communities and the Early Circulation of the Sufi Occultist Aḥmad al-Būnī’s Works

The Ifrīqiyan cum Cairene Sufi Aḥmad al-Būnī (d. ca 622/1225 or 630/1232-1233) is a key figure in the history of the Islamicate occult sciences, particularly with regard to the “science of letters and names” ( ʿilm al-ḥurūf wa-l-asmāʾ ). Drawing on textual and manuscript evidence, this paper examines the role of esotericism—religious secrecy and exclusivity—in al-Būnī’s thought and in the promulgation and early circulation of his works in Egypt and environs. It is argued that al-Būnī intended his works only for elite Sufi initiates, and that, in the century or so after his death, they indeed circulated primarily in “esotericist reading communities,” groups of learned Sufis who guarded their contents from those outside their own circles. This tendency toward esotericism, and the eventual exposure of al-Būnī’s texts to a wider readership, are contextualized in relation to broader developments in late-medieval Mediterranean culture.Le soufi ifrīqiyien puis cairote Aḥmad al-Būnī (m. ca 622/1225 ou 630/1232-1233) est une figure clef de l’histoire des sciences occultes islamiques, en particulier en ce qui concerne la « science des lettres et des noms » ( ʿilm al-ḥurūf wa-l-asmāʾ ). En s’appuyant sur des donnees textuelles et manuscrites, cet article examine le role de l’esoterisme—le secret et l’exclusivite religieux—dans la pensee d’al-Būnī et dans la promulgation et la diffusion premieres de ses œuvres en Egypte et dans les environs. Il est demontre qu’al-Būnī concut ses travaux uniquement a destination de l’elite des soufis inities et que, a son epoque et dans le siecle qui suivit sa mort, ceux-ci circulerent principalement dans les « communautes lettrees esoteristes », c’est-a-dire des groupes de soufis erudits qui preservaient leur contenu de ceux qui etaient en dehors de leur propre cercle. Cet engouement pour l’esoterisme et la propagation des textes d’al-Būnī a long terme aupres d’un public plus large sont contextualises a la lumiere de l’evolution de la culture mediterraneenne a la fin du Moyen Âge.This article is in English.
Two-stage genetic algorithm for parallel machines scheduling problem: Cyclic steam stimulation of high viscosity oil reservoirs

Abstract In this paper, the problem of optimal assignment of trailer-mounted steam generators for cyclic steam stimulation (CSS) of petroleum wells is formulated as a parallel uniform machines scheduling (PMS) problem with release dates. The total weighed tardiness is used as the goal of the optimization process. The distinctive features of the proposed PMS formulation include: jobs with variable weights, variable machine setup time, constraint capacity of drilling pads (where machines are allocated), and modified tardiness criterion. A two-stage scheduling algorithm combining heuristic and genetic algorithms is proposed for solving it. A chromosome representation, crossover and mutation operators generating only feasible solutions and thus avoiding the use of any repair mechanism are discussed. The performance of the algorithm is tested on a real-world data set from the oilfield asset located in the coastal swamps of the Gulf of Mexico. The experiments indicate that the proposed approach gives good results in optimization of the operational costs and petroleum recovery. The algorithm is implemented as a part of the software platform for optimization of CSS and currently is in use by oilfield engineers.
A Note on Chicano-Mexicano Cultural Capital: African-American Icons and Symbols in Chicano Art

Este articulo forma parte de un proyecto de investigacion mas amplio en proceso. En el se argumenta que la "transportacion" de "capital cultural" por los migrantes encontro tierra fertil entre la poblacion mexicoestadunidense ya establecida en los estados fronterizos entre Mexico y Estados Unidos. Se entiende como capital cultural el bagaje historico, las costumbres y la produccion de bienes simbolicos diarios que legitimizan y dan coherencia a una comunidad. Este capital cultural ha pasado por un proceso de transformacion en las comunidades mexicoestadunidenses. Muchas de las costumbres simbolicas tempranas han sido adaptadas a circunstancias nuevas. El uso de iconos y simbolos de herencia africomexicana por artistas chicanos, por un lado, y las discusiones sociales y politicas de una localidad cultural africoestadunidense, por otro, se han convertido en parte del capital cultural de las comunidades mexicoestadunidenses. Para entender la traduccion y la interpretacion del uso de estos bienes simbolicos, deben rescatarse algunos aspectos historicos claves. ABSTRACT This article forms part of a longer research project in progress. It argues that the "transportation" of "cultural capital" by the migrants found fertile ground among the Mexican-American population already established in the border states between Mexico and the United States. Cultural capital is understood as the historical bag-gage and daily practices and production of symbolic goods that legitimate and give coherence to a community. This cultural capital has undergone a process of transformation in the Mexican-American communities. Many of the early symbolic practices have been adapted to new circumstances. The use by several Chicano artists of icons and symbols of African-Mexican heritage on the one hand, and of social and political issues from an African-American cultural location on the other, have become part of the cultural capital of Mexican-American communities. To understand the translation and interpretation of the use of these symbolic goods key aspects of history must be highlighted.
On Hill's stress rate in the continuum mechanics of polycrystals

The lattice corotational stress rate, suggested byHill [1], is contrasted with the “material” co-rotational (Jaumann-Zaremba) stress rate and shown to be preferred in phenomenological continuum models of crystal behavior. A simple application to a crystal deforming via quasi-static single slip is included.
Nonlinear Outflows on a β Plane

Nonlinear analytical solutions and numerical simulations show that the behavior of inviscid (light) outflows on a β plane strongly depend on the orientation of the boundary along which they are situated. Both outflows associated with eastern and southern boundaries split into two branches. One branch contains a chain of eddies and the other corresponds to a steady boundary current. Outflows situated along a western boundary, on the other hand, produce a steady gyre and outflows situated along a northern boundary produce an exceptionally broad steady current.
The influence of neuropsychological characteristics on the use of CI therapy with persons with traumatic brain injury

The great prevalence of traumatic brain injury (TBI) and its high economic costs make reducing TBI-related disability a national health care priority. In our research laboratory, CI therapy has been found to significantly improve upper extremity function for persons with chronic TBI. The results have suggested that persons with TBI are less likely to adhere to critical components of the CI therapy protocol than participants with stroke in other studies. Treatment outcomes have also been more variable. Our findings suggest that some cognitive skills appear related to treatment outcome. In addition, cognitive and behavioral deficits, commonly seen with participants with TBI, challenge the delivery of the standard CI therapy protocol with some persons. We discuss the implications of these neuropsychological factors for CI therapy used for chronic TBI and propose further research to more thoroughly investigate these issues.
Nutritional Management of Hepatic Encephalopathy

Hepatic insufficiency is a common consequence of critical illness. The liver’s multiplicity of processes and its position astride the portal vein, where it receives nutrients and prepares them for distribution to the periphery, make it the central organ in any metabolic scheme. It is precisely this central role which causes the derangements of these processes in hepatic insufficiency to affect all phases of body economy.
Photoselection and Linear Dichroism of Retinal Isomers and Visual Pigments

It has been known for about ten years that when frozen solutions (glasses) of visual pigments at 77°K are illuminated with visible light, there are changes in the absorption spectrum of the pigments (1, 2, 3). These changes in the absorption spectrum, which in general are fairly small (less than 20 nm shifts in the absorption maxima), are dependent on the wavelength of the illuminating light and show the typical behavior of the photochromic systems.
Left bundle branch block-induced left ventricular remodeling and its potential for reverse remodeling

With the emergence of cardiac resynchronization therapy (CRT) as a powerful tool to reverse left ventricular dysfunction in patients with left bundle branch block (LBBB), there is increasing awareness that LBBB-induced dyssynchrony may be a primary cause of heart failure with reduced ejection fraction (HFrEF). Current guidelines for implanting CRT require at least 3 months of guideline-directed medical therapy (GDMT) before device implantation in the hopes that medications will reverse cardiomyopathy and obviate the need for device therapy. However, no randomized controlled trial demonstrating efficacy of medications ever stratified outcomes by patients with conduction abnormalities. Consequently, CRT, not GDMT, may be a more effective first-line therapy for patients with LBBB and HFrEF. This review evaluates the evidence for LBBB-induced cardiomyopathy, examines the rationale for GDMT in this population, and presents the evidence for direct implantation of CRT. It is likely that many patients would benefit from earlier intervention with CRT, though about 25% of patients with LBBB and HFrEF may respond to GDMT.
Human papillomavirus (HPV)-related oropharyngeal cancer cofactors: Viral co-infections, second cancers, and survival trends—A single Veterans Administration (VA) institution.

e17531Background: Oropharyngeal cancers related to HPV are increasing in number. Common factors associated with HPV related head and neck cancers include ethnicity, young age, and low usage of alco...
Video Modeling to Improve Customer Service Skills of an Employed Young Adult With Autism

Providing evidence-based interventions in competitive employment settings is critical to improve employment outcomes for individuals with autism. This study used a multiple baseline across behavior...
Enhancing the predictive capabilities of a composite plasticity model using cohesive zone modeling

Abstract One of the challenges in building a predictive numerical model for laminated composites is the ability to accurately model delamination. In this paper, a modular orthotropic plasticity model that is made of three sub-models – deformation, damage and failure, is used in conjunction with a delamination model to predict the behavior of an impact event involving a unidirectional laminated composite. Both the composite and delamination constitutive models are built entirely using experimentally obtained data. The delamination model that uses cohesive zone elements, is built using data obtained from double cantilever beam (DCB) and end-notched flexure (ENF) tests. An impact validation test is simulated, and the results are compared both qualitatively and quantitatively with experimental results to validate the both the cohesive zone element (CZE) parameters and the composite material model. The paper concludes with a summary of the work and ongoing work to improve experimental procedures and the constitutive model.
Outcomes and Quality of Life from Frontal Sinus Surgery

The goal of surgical treatment of frontal sinusitis is to improve the quality of life of patients. The purpose of this chapter is to summarize the evidence for the outcomes and quality of life related to surgical intervention of the frontal sinus. Studies report very high patency rates for Draf IIA procedures, and Draf III procedures have high rates of subjective improvement and neo-ostium patency in patients with recalcitrant disease. Balloon catheter dilation has shown favorable safety and effectiveness, while frontal sinus stenting serves as an adjunct to help decrease the risk of stenosis. As with all techniques and indications for surgical intervention, patient selection remains a key factor in outcomes.
To Code or Not to Code? Programming in Introductory CS Courses

Code-first approaches for introducing students to CS exclude those without preparatory privilege in programming and those intimidated by coding. Delaying coding or not using coding in an introductory CS course provides an equitable learning opportunity and includes a broader group of students in computational education. We present a study that compares a traditional Python code-first approach with an approach to delay or remove coding by first using simple, well-known stories to explain computation without the need for a computer or coding. We find that many students, especially female students and those without prior programming, are initially not interested in coding but in using stories to explain computing. We conclude that a traditional Python code-first approach excludes these students and an option using stories is a viable alternative.
Teaching Energy Physics for Environmental Studies: A Course Summary

This article summarizes a college course on energy physics for an environmental studies curriculum. The course was developed as an upper-division course. However, it has no physics prerequisite and...
Farmers' willingness to pay for various features of electronic food marketing platforms

This study utilizes a choice experiment to evaluate agricultural producers’ preferences and willingness to pay (WTP) for five features offered by electronic food marketing platforms. The attributes examined are: an online marketplace, social media advertisement of farms, different operators of the marketing platforms, an online directory, and monthly fee levels. The results in this study indicate heterogeneity in producers’ preferences. Specifically, farmers can be divided into two distinct groups: producers interested in electronic food trading platforms, and producers who are not interested in them. Producers in the first group are willing to pay $70 per month for an online marketplace and $152 per month for the service. Lastly, farmers have a slight preference for a for-profit operator when compared to a not-for-profit operator.
Water-Mediated Heterogeneously Catalyzed Reactions

Nature takes advantage of the pervasive presence of water to control many enzymatic reactions by utilizing the unique properties of water, which in turn help regulating reaction rates, selectivity,...
Parental consent: A potential barrier for underage teens' participation in an mHealth mental health intervention.

Abstract Purpose We sought to examine whether underage adolescents displaying symptoms for a mental illness (i.e., an eating disorder) would be willing to obtain parental consent to participate in a study to test the efficacy of an evidence-based mobile mental health intervention targeting teens with eating disorders. Methods The participants (n = 366) were 15 to 17 year-old English-speakers who post or follow social media accounts on Instagram that emphasize being thin as important or attractive. The participants were administered a survey through Qualtrics to assess eating disorder pathology, interest in trying an evidence-based mobile mental-health intervention, and comfort level with obtaining parental consent to partake in a research study about such an intervention. Results About 85% of participants met clinical or subclinical criteria for an eating disorder; however, only 12% had received a treatment within the past six months. While 83% of participants were interested in trying a mobile health interventions app, only 35% indicated willingness to obtain parental consent to participate in a research study. The primary reasons presented for unwillingness to obtain consent included importance of retaining privacy and feeling that parents lack awareness or understanding about mental health issues. Conclusions While barriers exist to obtaining treatment for eating disorders, a mobile intervention app may close some of these gaps. Many underage participants indicated interest in obtaining such treatment, yet only a third were willing to obtain parental consent. Future studies should investigate how to reduce these barriers to obtaining parental consent to facilitate teen access to research and mobile mental health treatment.
Sexual Health in the Elderly Population

Among the growing elderly population, sexual health remains an important concern for individuals and couples. An understanding of the expected changes with aging and taking care of aging men and women is important for treating sexual dysfunction. Sexual health issues related to aging can be both linked between men and women and independent. The aim of this study is to determine the most important considerations that contribute to sexual satisfaction in men and women in this population. Many factors contribute to the overall sexual health of men and women. Hypogonadism and erectile dysfunction both warrant thorough evaluation and consideration of treatment to improve sexual satisfaction. Underlying cardiovascular issues may be present in men presenting with these concerns. In addition to hormone replacement and traditional therapy for erectile dysfunction, therapeutic stem cell injection has shown some promise. Menopause, vaginal dryness, and dyspareunia play important roles in sexual satisfaction in women. Vaginal moisturizers, topical estrogen, and MonaLisa Touch laser therapy all may aid in improving these symptoms and ultimately sex lives. Studies have also demonstrated some benefit in populations with arousal disorders, which can be present in the elderly. Male patients often describe issues related to erectile dysfunction and hypogonadism, and issues with sexual drive. The pathophysiology is linked between these conditions and treatment of one component can provide symptom relief on a larger scale. A combination of testosterone therapy, lifestyle modifications, and therapy for erectile dysfunction relates to sexual satisfaction in men. In women, an understanding of the physiological process of menopause and offering therapy when indicated can improve the quality of sexual health and provide satisfaction to both patient and partner. While aging can diminish drive and desire, proper counseling and treatment may significantly benefit some patients. A multimodal approach involving the physician, patient, and partner will optimize care and may improve the quality of life in the elderly. This review outlines some normal changes due to aging and identifies some current treatment options for a population in which sexual health can be often ignored or dismissed. By understanding the available tools, a more comprehensive approach can be taken to achieve satisfaction in couples and individuals alike.
One-pot synthesis of linear triblock terpolymers and their aqueous self-assembly

Compartmentalized micelles are prepared through the self-assembly of linear triblock terpolymers containing hydrophilic (H), lipophilic (L), and fluorophilic (F) domains. The triblock copolymers were synthesized via living ring-opening metathesis polymerization (ROMP) of norbornene-based monomers. Our terpolymer design offers a facile approach for the synthesis of the target materials with fast polymerization kinetics, complete block incorporation and control over block sequence. Various triblock terpolymers are prepared with variations in block sequence and block ratio and self-assembled in aqueous media. Interaction parameter (χ) values between each block are determined using a Flory–Huggins based computational model. “Core–shell–corona”, “disk-like”, “raspberry-like” and “worm-like” morphologies are observed through cryogenic transmission electron microscopy and dissipative particle dynamics simulations.
The Fate of Periprosthetic Joint Infection With Corynebacterium striatum: A Rare but Catastrophic Causative Organism.

Abstract Background The virulence and antibiotic resistance profile of an infecting organism have been shown to impact the outcomes of periprosthetic joint infection (PJI). However, there are no existing data on the outcomes of PJI caused by Corynebacterium striatum, a rare organism. Thus, our objective is to ascertain: (1) the treatment success of PJI caused by this rare organism and (2) patient characteristics in the setting of C striatum PJI. Methods A retrospective review was conducted on 741 consecutive PJIs managed at 2 hospital facilities by 8 surgeons (February 4, 2015 to October 30, 2019). The inclusion criteria represented the presence of minimum 1 positive culture of C. striatum. After excluding 1 patient with no follow-up, 15 patients were finally analyzed (9 hips/6 knees). Out of 15 patients, 9 underwent explantation with spacer insertion, 5 underwent irrigation and debridement with polyexchange (I&D), and 1 underwent Girdlestone. Out of 9 explanted patients, only 6 cleared infection and were reimplanted. The clinical staging system for PJI was determined using McPherson classification. The mean follow-ups for I&D and explantation were 35 and 23.5 months, respectively. Success of reimplantation was determined using Delphi criteria. Results Out of 5 I&D patients, 40% had to be reoperated because of persistent infection. Out of 6 explanted patients who were reimplanted, 67% failed. According to McPherson, 40% of I&D and 22.2% of explanted patients were significantly compromised hosts. Conclusion C. striatum PJI has a high-treatment failure rate in patient undergoing I&D or 2-stage revision surgery. Surgeons should be aware of the difficulty controlling this PJI and advise patients accordingly.
Comprehensive study of terahertz metamaterial absorber by applying a hybrid approach on its circuit analogue

Here, we propose a hybrid approach to uniquely determine the elements of the circuit analogue of the terahertz metamaterial absorber that we previously reported. The proposed method is based on calculations, fitting, and physical mechanism of the absorption process interpreted by the model. In this work, the correlation between the model components and our designed absorber is comprehensively enlightened, and the dependence of the model elements to structural dimensions of the absorber is analyzed both qualitatively and quantitatively. By applying this approach on frequency selective surface (FSS) model, we are also able to interpret the polarization insensitivity of our designed absorber. The proposed model and approach is applicable for all metamaterial absorbers with any arbitrary FSS design.
The Legacy of Nixon—and Quincy

Perhaps it began with Watergate: the precipitating of confidence into the abyss of disbelief. Tolerance of citizens for the small errors of their government was shattered by their realization of major deceit on the part of their highest elected official. The mood of the people affected even the medicolegal officials, both elected and appointed. Citizens and the media alike now deemed it necessary and appropriate to question the determination and decisions, the rulings and resolutions of the many questions relating to death investigation.
Determining attainment of the EPAS foundation program objectives: Evidence for the use of self-efficacy as an outcome

Building on research related to social cognitive theory and its construct of self-efficacy, this article describes the development of the Foundation Practice Self-Efficacy scale. This measure is designed to assess graduate social work programs' attempts to achieve the educational policy objectives for foundation-year graduate study set by the Council on Social Work Education. Preliminary evidence regarding the reliability, validity, and sensitivity to change of this measure are presented. The authors discuss changes in MSW students' self-efficacy over the course of the foundation year.
High performance reliable file transfers using automatic many-to-many parallelization

Shift is a lightweight framework for high performance local and remote file transfers that provides resiliency across a wide variety of failure scenarios. Shift supports multiple file transport protocols with automatic selection of the most appropriate mechanism between each pair of participating hosts allowing it to adapt to heterogeneous clients with differing software and network access restrictions. File system information is gathered from clients and servers to detect file system equivalence and enable path rewriting so that multiple clients can be automatically spawned in parallel to carry out both single and multi-file transfers to multiple servers selected according to load and availability. This improves both reliability and performance by eliminating single points of failure and overcoming single system bottlenecks. End-to-end integrity is provided using cryptographic hashes at the source and destination with support for partial file retransmission of only corrupted portions. This paper presents the design and implementation of Shift and details the mechanisms utilized to enhance the reliability and performance of file transfers.
Use of an E-text as a Primary Course Resource

For 3 years, the author collected user input concerning the use of two e-texts as the primary resources for the University of Oklahoma Construction Science Construction Administration and Construction Equipment and Methods courses. Because of the departure from using traditional hard-bound texts, the author hoped to affirm from user input that the e-texts were effective and suitable as the primary course resources. Users completed a survey at the end of each of the six offerings, addressing their perceptions about the e-texts' use and delivery. Survey results included in this article are categorized and reported by Construction Administration E-text and Heavy Construction Equipment Basics E-text, course offering (Fall 2003 through Spring 2006) and as a whole. Along with reporting survey results this article describes the e-texts' content and delivery. Based on survey results, comments from users and the author's past experience of using traditional texts in these courses, these e-texts appear to be effect...
Animated graphical user (AGUI) model in desktop and mobil computer devices

Since the beginning of computers there have been many types of user interfaces. Early user interfaces were extremely limited because of the computers limited resources. As computing systems and computing power evolve, so have the user interfaces evolved. The current stage of evolution for graphical user interfaces (GUI) for most computer systems is the WIMP (Windows, Icons, Mice, Pointer). The WIMP graphical user interface design has been the standard since its conception in the 1970s. Progressing beyond the WIMP to the next level of graphical user interface has proven extremely difficult [1]. Animated Graphical User Interfaces (AGUI) are a significant improvement over windowed interfaces for some applications. The users perceived usefulness, perceived value, and perceived quality can be improved by applying an Animated Graphical User Interface to the application. Improving the users perceived usefulness, perceived value, and perceived quality can lead to a significant increase in revenue for some applications. Advertising in traditional windowed applications is not widely accepted by users making it difficult to use as a revenue source. The introduction of an Animated Graphical User Interface to an application also gives rise to the option of introducing animated advertising in the application. Animated advertising can present a new revenue source in addition to or in place of the purchase price of the application. Animated advertisements can be presented in an entertaining and passive format that users will find acceptable in applications where advertising is not normally tolerated. The Animated Graphical User Interface can also be used to bridge language barriers. Animations for the interface can be designed with a goal of language independence. The user interface and animations can be designed with intuitive animations and graphics that users can understand without using a language. Animated applications designed for language independence can be used by people all over the world without modifications for language considerations. Design innovative user Animated Graphical User Interfaces that are functional and entertaining. Use the Animated Graphical User Interface Model to increase the users perceived usefulness, perceived quality, and perceived value of the target application. Create an environment using the Animated Graphical User Interface Model that instills user tolerance for animated advertising embedded in applications. Design animations, graphics and functionalities using the Animated Graphical User Interface Model that allows language independent use of the application.
Duty to Inform

Abstract This article describes efforts to integrate vicarious trauma (VT) content into a fourth semester required course. Drawing on the literature of burnout, empathy, countertransference and VT, four pedagogical concepts are discussed: knowledge about trauma, personal attitudes and reactions, organizational awareness and spiritual renewal. Self-care is described to ameliorate the emotional and cognitive effects of VT.
γ-Sarcoglycan deficiency increases cell contractility, apoptosis and MAPK pathway activation but does not affect adhesion

The functions of γ-sarcoglycan (γSG) in normal myotubes are largely unknown, however γSG is known to assemble into a key membrane complex with dystroglycan and its deficiency is one known cause of limb-girdle muscular dystrophy. Previous findings of apoptosis from γSG-deficient mice are extended here to cell culture where apoptosis is seen to increase more than tenfold in γSG-deficient myotubes compared with normal cells. The deficient myotubes also exhibit an increased contractile prestress that results in greater shortening and widening when the cells are either lightly detached or self-detached. However, micropipette-forced peeling of single myotubes revealed no significant difference in cell adhesion. Consistent with a more contractile phenotype, acto-myosin striations were more prominent in γSG-deficient myotubes than in normal cells. An initial phosphoscreen of more than 12 signaling proteins revealed a number of differences between normal and γSG–/– muscle, both before and after stretching. MAPK-pathway proteins displayed the largest changes in activation, although significant phosphorylation also appeared for other proteins linked to hypertension. We conclude that γSG normally moderates contractile prestress in skeletal muscle, and we propose a role for γSG in membrane-based signaling of the effects of prestress and sarcomerogenesis.
An Exploration of Marketing's Impacts on Society: A Perspective Linked to Democracy

Abstract The authors propose a political theory perspective for examining the impact of the modern aggregate marketing system on consumer welfare and society. Specifically, they suggest that the benefits marketing delivers to consumers are similar to the conditions required for representative democracy. This perspective encompasses a broader range of benefits than is usually considered in the marketing literature and could provide a possible template for evaluating marketing actions. Viewing marketing as democratic is consistent with the historical evolution of marketing and with existing definitions of marketing. Linking marketing to political science begins to connect individual-level outcomes with societal outcomes. The approach also lends itself to policy discussions and further research on the relationships among the three primary actors in the marketing system: consumers, marketers, and government. It raises several questions about optimal marketing systems.
Martingale dynamics and optimal routing in a network

In this paper, we consider a dynamic routing problem in a store-and-forward computer-communication network which consists of l parallel channels connected between the source and the destination. We prove that if messages arrive at the network in accordance with a Poisson process and all nodes have an exponential service rate, then the routing strategy that minimizes the total expected time in transmitting all messages that arrive before T>0 is to route the arriving message to the channel along which the sum of all queue sizes is minimum. Techniques of martingale and dynamic programming are used in obtaining the result.
Grain oriented ferroelectric PZT thin films on lattice-matched substrates

Abstract The sol-gel technique has been used to produce highly grain-oriented perovskite PZT thin films on lattice-matched SBN:60, SrTiO 3 and MgO substrates. These films were deposited on both La 0.5 Sr 0.5 CoO 3 (LSC) laser ablated-coated and uncoated substrates and annealed in the range of 630–675°C in an air or oxygen atmosphere. In all cases the PZT thin films were highly crystalline and oriented, with dielectric constants higher than 1100. The measured remanent polarization in these films exceeded 18 μcoul/cm 2 indicating the potential for strong electro-optic and piezoelectric effects.
Regulating the proton budget of higher plant photosynthesis

In higher plant chloroplasts, transthylakoid proton motive force serves both to drive the synthesis of ATP and to regulate light capture by the photosynthetic antenna to prevent photodamage. In vivo probes of the proton circuit in wild-type and a mutant strain of Arabidopsis thaliana show that regulation of light capture is modulated primarily by altering the resistance of proton efflux from the thylakoid lumen, whereas modulation of proton influx through cyclic electron flow around photosystem I is suggested to play a role in regulating the ATP/NADPH output ratio of the light reactions.