cssi/SciSciGPT-SciSciNet huggingface dataset:
Dietetic Preceptors Perceive Their Role to Include a Variety of Elements

Abstract Preceptors are widely used among supervised practice programs in dietetics education. The majority of information regarding preceptors and the preceptor model has been conducted outside of dietetics and has focused on the characteristics of a preceptor or the advantages and disadvantages to the preceptorship. The literature reveals that although many definitions are used to describe the "preceptor," the role of a dietetic preceptor in supervised practice has not been distinguished. The purpose of this study was to determine role perceptions among dietetic preceptors by their indications of how they currently practice vs how they believe they should practice. Directors of dietetic internships, coordinated programs, and approved preprofessional practice programs were selected via a stratified, random sampling to distribute survey materials to 3 preceptors in their programs. The mailed survey was used to gather data detailing demographic characteristics, characteristics of current precepting practices, and beliefs regarding how precepting should be executed. Utilizing concept analysis, a typology was devised. The Preceptor Typology instrument served as the foundation from which the questionnaire was based. Program directors distributed 409 survey packets; usable data were collected from 265 preceptors (64.8%). Descriptive statistics and cross-tabulations were used to analyze data. Preceptors were confident in their understanding of the preceptor role. Data revealed that preceptors perceive their role to include a variety of tasks, which may or may not be essential to the precepting role. Preceptors also indicated that they were satisfied with their performance of what they considered to be preceptor responsibilities. More than 80% specified an "excellent" or "good" understanding of what was expected of them, although greater than 85% indicated that preceptor training materials would be beneficial. Training programs should be designed to address the unique role of the preceptor and how precepting complements the sequence of dietetics education. J Am Diet Assoc. 2002; 102:968-974 .
THE LOCK BOX: AN INSTRUMENT TO EVALUATE MENTAL ORGANIZATION IN PRESCHOOL CHILDREN

SUMMARY The Lock Box, a large rectangular container with 10 latched doors, each housing a different toy, is designed to investigate mental organization in young children. It differs from general intelligence and special ability tests by emphasizing how a child approaches a problematic situation, rather than how much he knows. The Box has received preliminary validation as a diagnostic instrument in a study of 57 retarded and normal youngsters. In addition to its use as a screening instrument for mental retardation, the Box may identify mental disorganization in normal children (the cognitively hyperactive/distractible group) as well as good mental organization in retarded children (the delayed but not deviant retarded group).
Covalent binding of carbaryl (1-naphthyl-N-ethylcarbamate) to rat liver microsomes in vitro

Abstract Enzyme mediated binding of carbaryl (1-naphthyl- N -methylcarbamate) to rat hepatic microsomes occurred in vitro in the presence of reduced nicotinamide adenine dinucleotide phosphate (NADPH) and oxygen and was inhibited by nitrogen, carbon monoxide, reduced glutathione, cysteine, N -ethyl maleimide, and 2-diethylaminoethyl-2,2'-diphenylvalerate-HCl (SKF 525-A). Binding was markedly increased, 2- to 3-fold, by pretreatment of animals with phenobarbital or 3-methylcholanthrene and appeared to be dependent on the production of an active metabolite which was formed oxidatively in liver microsomes by cytochrome P -450 mixed-function oxidases. SDS-polyacrylamide disc gel electrophoresis of ether-extracted, solubilized microsomes and the distribution of radioactivity after Pronase digestion, treatment with 1-fluoro-2,4-dinitrobenzene, and extraction with ethyl acetate and ether at pH 9 and 1 indicated that the radiolabeled products were covalently bound to amino acid residues of microsomal protein.
Analyzing the physical correctness of interpolated human motion

Two human motions can be linearly interpolated to produce a new motion, giving the animator control over the length of a jump, the speed of walking, or the height of a kick. Over the past ten years, this simple technique has been shown to produce surprisingly natural looking results. In this paper we analyze the motions produced by this technique for physical correctness and suggest small modifications to the standard interpolation technique that in some circumstances will produce significantly more natural looking motion.
A pattern matching system for linking TCAD and EDA

A software system has been written that analyzes a mask layout and searches for locations sensitive to residual processing effects. Pattern matching is used to determine where the layout geometry most closely resembles a problematic shape. The system was designed to quickly provide feedback to the designer as to which areas in the mask must be altered. The goal is to find and rank order the locations of the worst-case effects in a full chip layout within an hour. A number of different algorithms have been developed based on converting the layout from polygons to a bitmap, edges, or rectangles and triangles. Higher-order primitives such as rectangles require that the pattern be pre-integrated in one or two dimensions. Results employing the rectangle and triangle algorithm show that all edges on a mask layer of several square centimeters can be processed in less than an hour.
A General Interindustry Relatedness Index

For empirical work in the resource-based view of the firm, characterizing the resources that are responsible for firm growth is difficult because valuable resources are often tacit, ambiguous, or difficult to identify. This is a particular problem for empirical assessments that rely upon the concept of relatedness between resources to characterize the direction of growth of the firm. We tackle the problem for the general case by developing a general interindustry relatedness index. The index harnesses the relatedness information embedded in the multiproduct organization decisions of every diversified firm in the U.S. manufacturing economy. The index is general in that it can be used across industry contexts without requiring explicit identification of resources and it provides a percentile relatedness rank for every possible pair of four-digit Standard Industrial Classification manufacturing industries. The general index is tested for predictive validity and found to perform as expected. Applications of the index in strategy research are suggested.
Effects of fine-grain habitat complexity on egg parasitism by three species of Trichogramma

Effects of microhabitat complexity on host foraging by three species of Trichogramma (T. deion, T. ostriniae, and T. pretiosum) were evaluated under simulated stored product conditions. All three species have been considered as potential biological control agents for the Indianmeal moth, Plodia interpunctella, in retail stores and warehouses. Trials were conducted with single naive female parasitoids in 10-cm Petri dishes that were either empty, contained flour, or contained millet. Empty 15-cm Petri dishes, which served as a surface area control, comprised a fourth treatment. Females were allowed to forage for sentinel egg disks for 2 h, after which percentages of para- sitism and egg mortality were computed. In addition, behavioral observations were made on a subset of the trials. Trichogramma deion parasitized more eggs than the other two species in the empty dishes and in the dish containing flour. For T. deion, rates of parasitism and egg mortality were significantly greater in both the small and large empty dishes than in the small dishes containing flour or millet. Par- asitism was consistently low for all three species in the grain-filled dishes. Among species, T. ostriniae spent the most time walking, while T. pretiosum was the most sedentary. In addition, T. pretiosum spent significantly more time on the first egg visited compared with sub- sequent eggs. T. deion may be the best-suited for use as a biological control agent for P. interpunctella. However, the potential negative effects of fine-grain habitat complexity should be taken into account when developing a release protocol for Trichogramma spp. 2008 Elsevier Inc. All rights reserved.
Studies on the effect of storage on the purity of sodium iodide-I 131.

Solutions of Nal131 upon storage show the presence of several bands (usually six inclusive of Nal131) when chromatographed one dimensionally in an ascending technique with various solvent mixtures and radioautographed. The percentage of radioactivity in the bands other than Nal131 increases rapidly upon storage at room temperature. Incubation of NaI131 solutions under nitrogen for 1½ hours with 40 mg./ml. of cysteine at pH 4 or pH 7 or 10 nig./ml. of Nal127 or Kl127 at pH 7 converges the extraneous bands into the Nal131 band. Preliminary studies rule out the possibility that the bands other than Nal131 are due to oxides of iodine or due to iodides other than Nal131. Studies on the uptake of the Nal131 or the major extraneous band by day old chick thyroids indicate that 20% of the injected radioactivity of the extraneous band is collected in the thyroid in contrast to the 60% uptake of Nal131.
Instrument packages to study long term sediment transport processes in a shallow bay

Pressure and near-surface and near-bottom measurements of current, temperature, salinity and light transmission were required in Mobile Bay, a 3 m deep estuary on the Gulf of Mexico. This environment presented several obstacles to obtaining long term observations. Boat traffic, soft estuary bottom, heavy biofouling, rapid sample rates and large data storage were overcome by using instrumentation techniques that are applicable to other estuary systems. Nearly two years of continuous data was collected. >
Alcohol consumption enhances fatty acid ω‐oxidation, with a greater increase in male than in female rats

Because ethanol inhibits mitochondrial fatty acid oxidation, with substantial accumulation of fatty acids in the livers of female (but not male) rats, and induces microsomal activities, we assessed possible changes in omega-oxidation. To study this, we pair-fed 24 male and 24 female littermate rats of the same age liquid diets containing 36% of energy either as ethanol or as additional carbohydrate for 4 wk. In controls, the microsomal omega-hydroxylation of lauric acid was 28% greater in female than in male rats (p < 0.05). Ethanol feeding significantly increased this activity in both genders (p < 0.01), but the rise in male rats (89%) was significantly higher than that in female rats (24%). This activity was unaffected by the presence of ethanol in the assay. The effects of ethanol were associated with increases in the content of cytochrome P-450 4A1 (as assessed in Western blots by the reactivity against a sheep antibody against P-450 4A1), and more so in male than in female rats. Despite possible competition by ethanol with the hydroxy fatty acid oxidation to dicarboxylic acids through alcohol dehydrogenase, suberic and sebacic acids accumulated significantly in the livers of alcohol-fed male rats. These effects of ethanol and gender on omega-oxidation paralleled those on the hepatic cytosolic fatty acid-binding protein and fatty acid esterification previously reported in similarly treated rats. Dicarboxylic acid products of omega-oxidation have been incriminated as mediators of similar effects by other drugs.(ABSTRACT TRUNCATED AT 250 WORDS)
Antiferromagnetism in semiconducting KFe 0.85 Ag 1.15 Te 2 single crystals

We have synthesized single crystals of K${}_{1.00(3)}$Fe${}_{0.85(2)}$Ag${}_{1.15(2)}$Te${}_{2.0(1)}$. The material crystallizes in the ThCr${}_{2}$Si${}_{2}$ structure with $I$4/mmm symmetry and without K and Fe/Ag deficiencies, unlike in K${}_{x}$Fe${}_{2\ensuremath{-}y}$Se${}_{2}$ and K${}_{x}$Fe${}_{2\ensuremath{-}y}$S${}_{2}$. Transport, magnetic, and heat-capacity measurements indicate that KFe${}_{0.85}$Ag${}_{1.15}$Te${}_{2}$ is a semiconductor with long-range antiferromagnetic transition at ${T}_{N}$ $=$ 35 K.
Highly Active Combination of BRD4 Antagonist and Histone Deacetylase Inhibitor against Human Acute Myelogenous Leukemia Cells

The bromodomain and extra-terminal (BET) protein family members, including BRD4, bind to acetylated lysines on histones and regulate the expression of important oncogenes, for example, c-MYC and BCL2. Here, we demonstrate the sensitizing effects of the histone hyperacetylation-inducing pan–histone deacetylase (HDAC) inhibitor panobinostat on human acute myelogenous leukemia (AML) blast progenitor cells (BPC) to the BET protein antagonist JQ1. Treatment with JQ1, but not its inactive enantiomer (R-JQ1), was highly lethal against AML BPCs expressing mutant NPM1c+ with or without coexpression of FLT3-ITD or AML expressing mixed lineage leukemia fusion oncoprotein. JQ1 treatment reduced binding of BRD4 and RNA polymerase II to the DNA of c-MYC and BCL2 and reduced their levels in the AML cells. Cotreatment with JQ1 and the HDAC inhibitor panobinostat synergistically induced apoptosis of the AML BPCs, but not of normal CD34+ hematopoietic progenitor cells. This was associated with greater attenuation of c-MYC and BCL2, while increasing p21, BIM, and cleaved PARP levels in the AML BPCs. Cotreatment with JQ1 and panobinostat significantly improved the survival of the NOD/SCID mice engrafted with OCI-AML3 or MOLM13 cells ( P < 0.01). These findings highlight cotreatment with a BRD4 antagonist and an HDAC inhibitor as a potentially efficacious therapy of AML. Mol Cancer Ther; 13(5); 1142–54. ©2014 AACR . See related article by Liu et al., [p. 1194][1] [1]: /lookup/volpage/13/1194?iss=5
The effect of F and Cl on the kinetics of albite crystallization; a model for granitic pegmatites?

Crystallization kinetics of albite from melts in the system NaAlSi3Os-H2O are not dramatically changed by the addition of l-2 wt.qo F or Cl. Vapor-undersaturated liquidus temperatures in the hydrous system are lowered 25 to 50'C in the presence of F, whereas Cl does not appreciably change the temperature of the hydrous liquidus. A Cl-rich vapor phase is found in the Cl-bearing systems. At 900"C and undercoolings of 40 to 70oC, rates of albite growth range from 1.4 to 2.2 X 10-6 cmls in the F-bearing hydrous system (compared to 1.4 to 3.2X 10-6 cmls in the F-free hydrous system at similar undercoolings). The growth rate of albite in the presence of about I wt.Yo Cl (and 2 wt.% H2O) at an undercooling of 90oC is 0.6 X 10-6 cmls. Nucleation lag is 0-10 hours in the F-bearing hydrous system, 10-24 hours in the hydrous system_, and 38 hours in the Cl-bearing hydrous system. Growth rates at 850oC are highest in the hydrous system (71.1 X 10-6 cmlg), but are elevated (relative to rates at 900'C) for both the F-bearing Q.l-6.3 X l0-o cmls) and Cl-bearing (1.2 X l0-o cmls) hydrous systems. Lag times for nucleation at 850'C in the Cl-bearing system (20 hours) are longer than in the hydrous or F-bearing systems (0-9 hours). The presence of a Cl-rich vapor phase seems to delay albite nucleation. Large crystals in pegmatites are not formed by high rates of crystal growth induced by elevated F or Cl contents. They may be related to a prolonged irterval of crystallization coupled with a reduced viscosity promoted by the fluxing action of components such as F and a range of nucleation events related to delayed nucleation in the presence of a vapor phase.
Bankruptcy and Texas Homesteads: Basic Principles and Current Issues

This paper provides an overview of the homestead exemption and discusses some difficult homestead issues that arise in Texas bankruptcies. Issues discussed include: (a) exemptions of a less-than-fee-simple interest in a homestead; (b) the interaction of the bankruptcy exemption regime with the Texas rule protecting proceeds of sales of homesteads for six months; and (c) efforts to evade the homestead exemption through sham transactions.These are the written materials to accompany the presentation given by Hon. Tony M. Davis at the 31st Annual Jay L. Westbrook Bankruptcy Conference in Austin, Texas (Nov. 2013).
Enteroviral Meningitis without CSF Pleocytosis

Researchers at Seoul National University and other centers in Korea examined the clinical characteristics of enteroviral meningitis in 390 infants and children; 16-18% were without CSF pleocytosis.
A Tolerance For Ambiguity

A student came to our program with a background in engineering—a field that is not characterized by ambiguity. She was struck by one of my comments on the first day of class and went home to tell her sister, a musician. Her sister titled a song and the CD “Tolerance for Ambiguity.”1 I had told the students that in their careers—beginning with their physical therapist education—they would have to develop a “high tolerance for ambiguity.” The musician's response to this was “wo[e], major, wo[e],” a phrase that continues to be echoed throughout our profession about the need to develop a tolerance for ambiguity. Perhaps the presence of ambiguity is related to independence in clinical decision making, growth of knowledge, and professional maturation. We didn't need a tolerance for ambiguity when we were told what to do. Now, ambiguity provides the context as we search for meaningful ways to identify the best examination procedure or the most effective intervention. First, we had to recognize and accept ambiguity. Now, we should be seeking knowledge to reduce that ambiguity. I began clinical practice in 1972. Then, a singular “proper” procedure was expected when working with patients in rehabilitation. The physician examined the patient, conducted the evaluation, and provided the therapists with a specific prescription. The prescription detailed each intervention—including the duration, frequency, and intensity of every aspect of that intervention. The therapist performed the prescribed intervention and reported progress at team meetings. Nothing was viewed as ambiguous. When I questioned the need for such specific “orders,” the chair of rehabilitation medicine reminded me that I was employed in a teaching hospital where the mission included training medical residents. The boundaries of my role in the plan of care were unquestionable. I railed at the chair's response, asking why someone like me—with a …
Advances in the Techniques of Measuring and Estimating Consumer Expenditures

IN RECENT years the study of consumer expenditures has been directed along certain lines determined by developments in the middle thirties. In the years 1934 and 1935 three books appeared that stimulated a wide interest in the possibilities of interpretation and analysis of expenditure data and two comprehensive nationwide surveys were initiated that brought modern survey techniques into this field of inquiry. The publication of "America's Capacity to Consume"' in 1934 focussed attention on the use of data from
Rapid Prescreening for Antiviral Agents against HIV-1 Based on Their Inhibitory Activity in Site-Directed Immunoassays. Approaches Applicable to Epidemic HIV-1 Strains

Several compounds, including the triphenylmethane derivative aurintricarboxylic acid (ATA) and porphyrins, were reported to inhibit the binding of anti-V3 loop-specific antibodies to the V3 loop of...
Picosecond Chemistry of Collisionless Molecules in Supersonic Beams

The dynamics of collisionless intramolecular vibrational-energy redistribution (IVR), bond breakage, and bond formation in large isolated molecules is currently a very important and challenging problem. A fruitful approach to this problem involves the study, via direct measurements in the time domain, of the decay parameters of energetically excited molecules. Using such an approach one can determine unimolecular rate constants as well as study any quantum mechanical coherence phenomena that may be involved in a decay process. Furthermore, in cold beams these rates and coherence effects can be studied as a function of the energy and character of individual vibrational modes in a molecule. The results of such studies are important to understanding the nature of energy flow within molecules and to assessing the possibility of vibrational mode-selective laser chemistry [1].
The Subgenus Pompilinus in Mexico (Hymenoptera, Pompilidae)

The subgenus Pompilinus of the genus Anoplius is widely distributed throughout most of the globe, but appears to be best represented in the Nearctic region, where there are about twenty species and subspecies. The group is a difficult one, the differences between the species being slight and often rather subtle, while the amount of intraspecific variation is often not inconsiderable. I believe that future refinements in the systematics of the group will come from comparative ethological studies. However, additional distributional data are also of value, and for this reason a review of the Mexican fauna of Pompilinus is presented at this time. Mexican records were omitted from the writer's recent revision of this group (Evans, 1951, pp. 277–325) for the simple reason that material from that country was then unavailable. The greater part of Mexico is a legitimate part of the Nearctic zoogeographical region, and in fact the Mexican highlands have played an important role in the distribution patterns of many North American Hymenoptera.
Carrion's Disease. I. Behavior of the Etiological Agent Within Cells Growing or Surviving in vitro.∗:

ConclusionsOrganisms cultivated in leptospira-medium, whether from the blood or tissues of Oroya-fever patients or from cutaneous nodules excised from patients with verruga peruana, invariably behaved as facultative intracellular parasites when cultivated in vitro with growing or surviving mammalian cells. Organisms cultivated from the blood of monkeys infected with human material from either Oroya fever or verruga peruana patients behaved similarly. A characteristic and uniform pattern of intracytoplasmic clustering was obtained with cultures from all of the above sources, this pattern being essentially identical with that seen in naturally infected human cells in both conditions (see Paper II). These observations substantiate the belief that Oroya fever and verruga peruana are caused by the same microorganism.
Avoidance responses to pure tones in the rat

Shuttle-box avoidance responses to pure tone stimuli at intensities from 0 to 115 db SPL were recorded for two male albino rats. Functions relating response probability to stimulus intensity were approximately linear in form, with the overall level of response being higher at higher stimulus frequencies.
Interlaminar Shear Strength Investigation of Aligned Carbon Nanotube-Reinforced Prepreg Composite Interfaces

Aligned carbon nanotubes (A-CNTs) placed at the interlayer between plies of a carbon fiber reinforced polymer composite (CFRP) material have been shown to increase interlaminar toughness and positively impact in-plane laminate strength, presumably by increasing both strength and toughness of the interface. Here, interlaminar shear strength (ILSS) is evaluated for this “nanostitch” architecture utilizing short beam shear (SBS) tests of an aerospace-grade unidirectional carbon fiber prepreg laminate. The A-CNT length is varied from 5 to 25 microns and was observed to compress during autoclave manufacturing laminates such that there is no observed difference in interlaminar or laminate thickness between the nanostitched and baseline specimens. An average shear strength increase of 6.5% is observed across the range of CNT lengths studied. Evidence of ply-jumping and offaxis failure suggest that this value is a lower limit for ILSS improvement. Future work will extend the length range to identify an optimum for ILSS improvement.
Intimate internationalisms: 1970s ‘Third World’ queer feminist solidarity with Chile

This article theorises the relationship between 1970s US Third World queer and feminist movements and Latin American anti-imperialist revolutions of the late twentieth century. I focus upon the historically occluded relationships between Third World feminists and queers in Chile and the United States throughout the transition to neoliberalism. My archive includes June Jordan’s little-known writings on Chile, the writings of Audre Lorde, and, primarily, a 1973 Third World feminist poetry reading staged in San Francisco shortly after the Pinochet coup. By assembling this unconventional archive, I intervene into the domestication of US anti-racist queer, black and feminist of colour politics. I argue for the profoundly internationalist foundation of these formations. I work to re-animate a moment when the affective economies of anti-colonial ‘global revolution’ opened up space for the imagination of joint struggle – allowing a visceral sense of struggle’s urgency and vitality in ways that have since been par...
FELIPE POEY, HYPERBOLE, AND THE MYTH OF THE "ISOLATED GENIUS" AMONG SPANISH AND LATIN AMERICAN SCIENTISTS

0 0 1 158 901 SIUE 7 2 1057 14.0 96 Normal 0 false false false EN-US JA X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman";} Felipe Poey y Aloy was a Cuban naturalist and intellectual who greatly contributed to the advance of science in Cuba. Despite being an autodidact he showed a great deal of competence as a scholar, teacher, and organizer of intellectual institutions in both the public and private spheres. Although being portrayed as an almost “isolated genius” he maintained a very broad and vigorous network of communications with scientists all over the world. He always kept an open mind and adapted to new scientific ideas. Although the narrative of his life and accomplishments has been the subject of much hagiography we contend that such narratives have obscured, rather than illuminated, his contributions to society and the social, political, and economic contexts under which he had to develop his work. Felipe Poey fue un naturalista e intelectual cubano que, en gran medida contribuyo al desarrollo de la ciencia en Cuba. A pesar de ser autodidacta, Poey demostro ser muy competente como academico, maestro y organizador de instituciones intelectuales tanto publicas como privadas. A pesar de ser representado como un “genio aislado”, Poey mantuvo una amplia y muy activa red de comunicacion con cientificos de todo el mundo. El siempre mantuvo su mente abierta a nuevas ideas cientificas. Sin embargo, la narrativa de su vida y sus logros ha sido objeto de mucha hagiografia. Este articulo sostiene que tales narrativas, en vez de iluminar, han opacado las contribuciones de Poey a la sociedad y al contexto economico politico y social en el que el tuvo que desarrollar su trabajo.
Comparison of Culture-Based Methods for Identification of Colonization with Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus in the Context of Cocolonization

Two screening methods to detect staphylococcal colonization in humans were compared. Direct plating to CHROMagar (BD Diagnostics) was compared to a broth preenrichment followed by plating to Baird-Parker agar. The broth-enrichment method was comparable to CHROMagar for methicillin-resistant Staphylococcus aureas (MRSA) detection, but the enrichment method was optimum for recovery of coagulase-positive Staphylococcus spp.
Computably Enumerable Sets

This chapter is intended to give the reader a more intuitive feeling for c.e. sets, their alternative characterizations, and their most useful static and dynamic properties. We also prove the Recursion Theorem 2.2.1 (Fixed Point Theorem), which will be a very useful tool, and we apply it to prove Myhill's Theorem 2.4.6 that all creative sets are computably isomorphic.
659 The role of body mass index on childhood pedestrian injury risk

Background Road traffic deaths rank as the 2 nd leading cause of death worldwide in children aged 5 to 9 years old. Child pedestrians are particularly vulnerable. Many risk factors have been identified as contributing to childhood pedestrian injury risk, but the role of obesity is less well understood. Obesity affects children’s physical and cognitive abilities, both of which could substantially influence a child’s ability to choose a safe route and to cross roads safely. Methods Two hundred and forty 7- and 8-year-old children completed a series of road crossings in a semi-immersive virtual environment by watching traffic and stepping off of a curb onto a trigger plate when they felt it was safe to cross. Road crossing performance was assessed via measures of attention, wait time, movement timing, and crashes. Route selection was assessed by asking children to choose the safest route to a destination using vignettes and a tabletop model. BMI was calculated using BMI-for-age growth charts for boys and girls. Results Children with higher BMI were riskier than peers with lower BMI on measures of waiting before crossing, time to spare relative to oncoming vehicles, and crashes with virtual traffic. BMI was not related to route selection. Conclusions Childhood obesity is an important risk factor for pedestrian injury. In particular, children with high BMI had difficulty perceiving and acting on gaps in traffic.
Foreword: Nonfinancial Barriers To Health Care

Health care policy traditionally has been seen as a three-legged stool. Three interdependent variables-cost, quality, and access-have largely defined the domain of health policy. Ignore one of the variables, and the stool topples. It is not surprising, therefore, that health care policymakers have tended to view the problem of access to health care resources primarily in economic terms. Economic analysis of the access problem is useful because it gives policymakers a common methodology, vocabulary, and set of analytical tools that provide insights into the related problems of cost containment and quality, as well as the access issue. This in turn provides insights into the economic tradeoffs that each variable entails for the other two. After defining, measuring, and analyzing access in economic terms, economic analysis naturally tends to frame solutions in economic terms. Imagine, if only for a moment, that the Great Health Care Debate of 1994 had not sputtered and ultimately fizzled out. Suppose the financial barriers to health care had been removed and the ability to pay was no longer a factor in the cost-quality-access puzzle. What nonfinancial barriers would still impede access to health care goods and services? This question, or a similar one, was presented to the Texas Legislature, resulting in a grant to support a study on this issue. This study yielded the splendid report Nonfinancial Barriers to Health Care in Texas, as well as a conference and papers from which the articles for this Symposium issue of the Houston Law Review were derived.In his foreword to a Symposium issue, the author discusses findings in The Nonfinancial Barriers to Health Care report, and introduces other articles in the Symposium. The author also argues that the mentioned report deserves to be reviewed carefully by all who are concerned with the access question, not only in Texas but nationwide.
Gout: will the "King of Diseases" be the first rheumatic disease to be cured?

Gout is the most common inflammatory arthritis in adults in the Western world. Characterized by hyperuricemia and the effects of acute and chronic inflammation in joints and bursa, gout leads to an agonizing, chronically painful arthritis. Arthritis can also be accompanied by urate nephropathy and subcutaneous urate deposits (tophi). Exciting new developments in the last decade have brought back the focus on this interesting, crystal-induced chronic inflammatory condition. New insights include the role of NALP3 inflammasome-induced inflammation in acute gout, the characterization of diagnostic signs on ultrasound and dual-energy computed tomography imaging modalities, the recognition of target serum urate less than 6 mg/day as the goal for urate-lowering therapies, and evidence-based treatment guidelines. A better understanding of disease mechanisms has enabled drug discovery – three new urate-lowering drugs have been approved in the last decade, with several more in the pipeline. We now recognize the important role that environment and genetics play in the causation of gout. A focus on the cardiac, renal, and metabolic comorbidities of gout will help translational research and discovery over the next decade.
Review: Many drugs are effective for conversion of AF and maintenance of sinus rhythm

Source Citation Miller MR, McNamara RL, Segal JB, et al. Efficacy of agents for pharmacologic conversion of atrial fibrillation and subsequent maintenance of sinus rhythm. A meta-analysis of clinic...
Three-Dimensional Printing of “Green” Fuels for Low-Cost Small Spacecraft Propulsion Systems

This paper details the advantages of employing modern additive manufacturing methods to fabricate hybrid rocket fuels for intrinsically safe and green small spacecraft propulsion systems. Using add...
The Promise and Practice of Genetics on Diabetes Care: The Fog Rises to Reveal a Field of Genetic Complexity in HNF1B.

Diabetes is a common disease characterized by the disruption of glucose homeostasis that results when insulin, the hormone that converts glucose from the blood into energy used by the body’s cellular machinery, is absent (through autoimmune destruction of the pancreatic β-cells in type 1 diabetes) or inefficient (increased insulin resistance or reduced insulin sensitivity in type 2 diabetes). There are multiple pathways to developing diabetes, yet practically all involve an underlying genetic etiology with an environmental trigger. The extent of knowledge of genetic factors and environmental factors differs across the forms of diabetes. In the case of type 1 diabetes, the concordance in monozygotic twins (genetically identical) is ∼50%, with familial aggregation and modeling suggesting a major impact of genetics on risk (1). The genetic contribution to type 1 diabetes is well described, with HLA genes accounting for one-half of the genetic risk (2) and ∼50 other sites in the genome contributing the majority of the remaining genetic risk (3). The familial (heritable) contribution to type 2 diabetes has also been estimated through twin studies, with monozygotic twin concordance rising from ∼50% in middle age to nearly 80% later in life (4). Complexity in assessment of the contribution of genetic factors to type 2 diabetes arises from the impact of other familial and behavioral factors that are associated with risk, including obesity, reduced physical activity, and dietary habits. Although the overall risk of type 2 diabetes appears “more heritable” than type 1 diabetes, the estimated effects of ∼100 sites across the genome account for ∼10% of the risk (5). Similar investigations have shown other types of diabetes to be heritable, including neonatal diabetes (6), maturity-onset diabetes of the young (MODY) (7), gestational diabetes mellitus (8), and latent autoimmune diabetes in adults (LADA) (9), and numerous studies have shown diabetes complications …
A novel push-pull asteroid magnetic Tractor(MT)

Abstract The possibility of an asteroid striking the earth is well known. The chosen technique for diverting such an asteroid depends on the lead time measured from the determination that an asteroid has a large probability of colliding and the expected time of such a collision. There are a large number of possible deflection techniques that are available, each suited to different lead times. If the lead time is unpleasantly short, desperation measures such as using nuclear devices may apply. If the lead time is comfortably long, the heralded gravity tractor (GT) is a good option. It is capable of precisely and verifiably altering the orbit of a threatening asteroid. If the lead time happens to be somewhere between desperate and comfortable, it is not clear what option may be invoked. It is likely the most probable scenario to occur is one where the lead time is somewhere in between very short and very long. There is a plethora of different techniques in the literature, but some are so fanciful that their reliability would certainly be in question. There is a need for a new deflection technique that has the reliability and the precision of the gravity tractor but is able to produce larger deflection forces to handle much shorter lead times. This is the problem that this paper addresses. The proposed solution to this problem is a push-pull asteroid magnetic tractor(MT) that is shown to produce orders of magnitudes larger deflection forces and to accommodate much shorter lead times than the GT.
The Odessa Years: Shoshana Persitz and the Gamliel Library of Omanut Press (1918-1920)

Shoshana Zlatopolsky Persitz (1893-1969) was only 24-years old when she founded Omanut Press in Moscow, 1917, during that brief but heady period of Jewish cultural renaissance following the February Revolution. The daughter of one of the wealthiest Jews in Russia, Shoshana originally created Omanut as a means of bringing world literature into the treasury of the Hebrew language, but when her four-year-old son Gamliel died, she introduced a series of picture-books for children named the “Gamliel Library” after her son. Forced to move several times over the course of the next few years, from Moscow to Odessa and from Odessa to Frankfurt am Main, Shoshana nevertheless succeeded in producing some of the most beautiful children’s books ever printed in Hebrew. But up till now, scholars have been unsure of where, exactly, the books were first printed: in Odessa sometime around 1918 – or in Frankfurt am Main several years later? Now, thanks to books newly discovered in the Library of Congress, we are able to say that at least six of the picture-books were in fact published for the first time in Odessa. This article focuses on the creation of these beautiful books and the story behind their publication.
NtrC Adds a New Node to the Complex Regulatory Network of Biofilm Formation and vps Expression in Vibrio cholerae

The biofilm growth mode is important in both the intestinal and environmental phases of the Vibrio cholerae life cycle. Regulation of biofilm formation involves several transcriptional regulators and alternative sigma factors. One such factor is the alternative sigma factor RpoN, which positively regulates biofilm formation. RpoN requires bacterial enhancer-binding proteins (bEBPs) to initiate transcription. The V. cholerae genome encodes seven bEBPs (LuxO, VC1522, VC1926 [DctD-1], FlrC, NtrC, VCA0142 [DctD-2], and PgtA) that belong to the NtrC family of response regulators (RRs) of two-component regulatory systems. The contribution of these regulators to biofilm formation is not well understood. In this study, we analyzed biofilm formation and the regulation of vpsL expression by RpoN activators. Mutants lacking NtrC had increased biofilm formation and vpsL expression. NtrC negatively regulates the expression of core regulators of biofilm formation (vpsR, vpsT, and hapR). NtrC from V. cholerae supported growth and activated glnA expression when nitrogen availability was limited. However, the repressive activity of NtrC toward vpsL expression was not affected by the nitrogen sources present. This study unveils the role of NtrC as a regulator of vps expression and biofilm formation in V. choleraeIMPORTANCE Biofilms play an important role in the Vibrio cholerae life cycle, contributing to both environmental survival and transmission to a human host. Identifying key regulators of V. cholerae biofilm formation is necessary to fully understand how this important growth mode is modulated in response to various signals encountered in the environment and the host. In this study, we characterized the role of RRs that function as coactivators of RpoN in regulating biofilm formation and identified new components in the V. cholerae biofilm regulatory circuitry.
Nucleon Bombarded Semiconductors

Three types of effects due to nucleon bombardment are discussed: permanent effects due to transmutations which are particularly important in irradiation by slow neutrons; transient effects produced by the passage of heavy particles and electrons; and reversible effects produced by fast nucleons. These are due to vacancies and interstitials produced by collision, and the original condition of the lattice can be restored by heat treatment. Using fast electrons, it is possible to find the threshold energy necessary to produce a vacancy or interstitial in the germanium lattice (about 25 to 30 eV), in agreement with estimates made previously. The use of well-defined beams allows the production of p-n barriers in germanium and hence leads to the possibility of studying the properties of such barriers as a function of thickness and concentration of carriers. In other semiconductors, such as silicon, tellurium and lead sulphide, irradiation leads primarily to a very large decrease in conductivity.
Chapter 4 Ultrafast dynamics and phase changes in highly excited GaAs

Publisher Summary This chapter discusses ultrafast dynamics and phase changes in highly excited gallium arsenide (GaAs). The progress of science in modern times is often driven by improvements in the precision of observations of natural systems or in the scientist's ability to control systems in experiments. The first and most obvious characteristic of femtosecond lasers is that they produce pulses of shorter than five femtoseconds (fs). These short pulses can be used to observe phenomena with a time resolution 1,000 to 10,000 times greater than possible in any other experiment. The second key characteristic of femtosecond pulses is that they can deliver an enormous amount of power with just a modest quantity of total energy, because the energy is packed into such a short time. Consequently, the electrons in a solid reach extremely high temperatures while the atomic structure is still cold; this is a unique nonequilibrium excitation of a solid and can cause novel and unusual phase transitions.
Functional Heatmap: an automated and interactive pattern recognition tool to integrate time with multi-omics assays

Life science research is moving quickly towards large-scale experimental designs that are comprised of multiple tissues, time points, and samples. Omic time-series experiments offer answers to three big questions: what collective patterns do most analytes follow, which analytes follow an identical pattern or synchronize across multiple cohorts, and how do biological functions evolve over time. Existing tools fall short of robustly answering and visualizing all three questions in a unified interface. Functional Heatmap offers time-series data visualization through a Master Panel page, and Combined page to answer each of the three time-series questions. It dissects the complex multi-omics time-series readouts into patterned clusters with associated biological functions. It allows users to identify a cascade of functional changes over a time variable. Inversely, Functional Heatmap can compare a pattern with specific biology respond to multiple experimental conditions. All analyses are interactive, searchable, and exportable in a form of heatmap, line-chart, or text, and the results are easy to share, maintain, and reproduce on the web platform. Functional Heatmap is an automated and interactive tool that enables pattern recognition in time-series multi-omics assays. It significantly reduces the manual labour of pattern discovery and comparison by transferring statistical models into visual clues. The new pattern recognition feature will help researchers identify hidden trends driven by functional changes using multi-tissues/conditions on a time-series fashion from omic assays.
A case report of cholinergic rebound syndrome following abrupt low-dose clozapine discontinuation in a patient with type I bipolar affective disorder

Rebound cholinergic syndrome is a rare, but well known unwanted phenomenon occurring after abrupt clozapine discontinuation. There have been previous reported cases of cholinergic rebound in the literature; however, these reports described cholinergic rebound following cessation of high doses of clozapine in patients diagnosed with schizophrenia. Here, we report a case of rebound cholinergic syndrome and catatonia in a male patient three days after abrupt discontinuation of 50 mg of clozapine prescribed for type I bipolar affective disorder. A 66-year old male of Spanish origin, treated for type I bipolar affective disorder for 15 years and for Crohn disease, was brought to the emergency department because of a sudden onset of mutism, dysphagia and trismus. He was described catatonic and presented hypertension, tachycardia and tachypnea. His body temperature was normal and the laboratory tests were unremarkable at presentation. A head CT and an EEG were in the normal range. While reviewing his history, it appeared the he was on clozapine 50 mg a day, first introduced 2 months ago, during a previous hospitalization for a manic episode resistant to other mood stabilizers. For an unknown reason, the patient’s psychiatrist stopped clozapine three days before the admission and replaced it by risperidone 5 mg and quetiapine 200 mg daily. A cholinergic rebound syndrome was then evoked. The patient’s ability to speak recovered dramatically and fast after the intravenous administration of 2.5 mg of biperiden supporting the diagnosis. Risperidone and quetiapine were also stopped. The patient fully recovered in 20 days after the reintroduction of 50 mg of clozapine and 2.5 mg of biperiden daily. This case report underscores that cholinergic rebound syndrome may occur in patients suffering from bipolar affective disorders, being on clozapine as a mood stabilizer. The low dose clozapine does not preclude severe manifestations of the phenomenon. Progressive tapering should therefore be adopted in any case.
Superheroes in the Stacks: Halloween ComicFest and Wichita State University

Academic libraries’ graphic novel and comic book collections hold a wide appeal for both scholarly study and personal reading. Programming around these materials can attract diverse audiences to pr...
Nanoparticle drug delivery characterization for fluticasone propionate and in vitro testing1

Glucocorticoids, such as fluticasone propionate (FP), are used for the treatment of inflammation and alleviation of nasal symptoms and allergies, and as an antipruritic. However, both short- and lo...
An Inquiry into Liberty, Slavery, and Thomas Jefferson’s Place in American Memory

This article presents a guided inquiry into Thomas Jefferson’s place in American memory. It centers on Jefferson’s liberty-based articulations and his involvement in slavery, which are paradoxical ...
Understanding the Needs of Female Veterans

This commentary attempts to frame the article, “Safer Housing for Homeless Women Veterans,” in a wider context. It defines female veterans, homelessness, and military sexual trauma. This commentary also tackles a question that often confuses civilian providers regarding who has access to care at the Veterans Health Administration. It does not repeat in detail all of the recommendations in the article, but it advocates their broader use in shelters and transitional housing. Finally, I close with some thoughts about a new generation of young, homeless, female veterans who may have children and how to accommodate their needs.