cssi/SciSciGPT-SciSciNet huggingface dataset:
Using voice and print directives and warnings to supplement product manual instructions

The present research investigated the effect of supplemental messages on compliance with and recall of product manual instructions. During the unpacking of a computer disk drive supplemental messages were presented that concerned procedures to prevent product damage during installation. The supplemental messages were either presented by digitized voice (auditory) or by printed placard (visual). Two types of message were presented. Either the message gave specific warning instructions or directed users to a specific location in the product manual where the instructions were printed. Results show that the supplemental voice and print messages increased compliance behavior compared to the manual only. The voice message produced the greatest recall compared to print or no supplement. There was no effect of the warning vs directive manipulation. The results support the use of supplemental messages to communicate particularly important information. Implications for the delivery of warning instructions in product manuals are discussed. Relevance to industry: Manufacturers are responsible for warning users about hazards associated with foreseeable use or misuse of their products. The present study shows that a supplemental print or voice message combined with a typical product manual produces significantly higher compliance than the manual alone.
Link failure monitoring via network coding

In network tomography, we seek to infer link status parameters (delay, congestion, loss rates etc.) inside a network through end-to-end measurements at (external) boundary nodes. As can be expected, such approaches generically suffer from identifiability problems; i.e., status of links in a large number of network topologies is not identifiable. We introduce an innovative approach based on linear network coding that overcomes this problem. We provide sufficient conditions on network coding coefficients and training sequence under which any logical network is guaranteed to be identifiable. In addition, we show that it is possible to locate any congested link inside a network during an arbitrary amount of time by increasing size of transmitted packets, leading to raise in complexity of the method. Further, a probability of success is provided for a random network. OPNET is used to implement the concept and confirm the validity of the claims — simulation results confirm that LNC correctly detects the congested link in situations where standard probing based algorithm fails.
Copper Stabilizes a Heterodimer of the yCCS Metallochaperone and Its Target Superoxide Dismutase

The copper chaperone for superoxide dismutase (CCS) activates the antioxidant enzyme Cu,Zn-SOD (SOD1) by directly inserting the copper cofactor into the apo form of SOD1. Neither the mechanism of protein-protein recognition nor of metal transfer is clear. The metal transfer step has been proposed to occur within a transient copper donor/acceptor complex that is either a heterodimer or heterotetramer (i.e. a dimer of dimers). To determine the nature of this intermediate, we generated a mutant form of SOD1 by replacing a copper binding residue His-48 with phenylalanine. This protein cannot accept copper from CCS but does form a stable complex with apo- and Cu-CCS, as observed by immunoprecipitation and native gel electrophoresis. Fluorescence anisotropy measurements corroborate the formation of this species and further indicate that copper enhances the stability of the dimer by an order of magnitude. The copper form of the heterodimer was isolated by gel filtration chromatography and contains one copper and one zinc atom per heterodimer. These results support a mechanism for copper transfer in which CCS and SOD1 dock via their highly conserved dimer interfaces in a manner that precisely orients the Cys-rich copper donor sites of CCS and the His-rich acceptor sites of SOD1 to form a copper-bridged intermediate.
Experimental Measurement and Analysis of Microelectronics Application Polymer Materials Properties

A laser based surface scanning technique was utilized to measure the polyimide coated silicon wafer curvature resulting from thermal cycling and mismatch, Meanwhile, mechanical properties of polyimide thin film were characterized by DMA, TMA and tensile test. Based on the obtained material properties, A FEA model was developed to analyze the experimental results -reasonable correlation was obtained. p]Similar approaches were taken one step further in the MCM silicon substrate curvature measurement. In a MCM package with silicon substrate, epoxy adhesive, and ceramic package, substrate warpage was developed in a thermal cycle due to thermal mismatch between the substrate and the package and coupling effect linked by epoxy adhesive. Three different substrate curvature measurement techniques were applied to identify the substrate curvature and epoxy thin film properties were also well characterized. A 3D FEA model incorporating with the epoxy material properties was developed to analyze the substrate warpage and investigate an optimal package design.
Were past Chinese families complex? Household structures during the Tang Dynasty, 618–907 AD

The popular image of a traditional Chinese household is one of a large kin group composed of multiple-family units. However, reports on family size in China's past suggest that the average household size was not large in ancient times. Using population registers for Dunhuang and Turfan from the Tang Dynasty (618–907 ad), this article is the first serious attempt to analyze household structures in ancient China. While a high proportion of simple-family households were recorded in the registers, a significant number of complex households suggests that the distribution of Chinese households was bimodal. This pattern fits neither the model considered as typical for Western families nor that for Eastern families. Other issues covered include the frequency of living alone, the presence of slaves, the distribution of household heads by age and sex, and women's marriage patterns.
A coupled thermosphere/ionosphere general circulation model

The NCAR thermospheric general circulation model (TGCM) is extended to include a self-consistent aeronomic scheme of the thermosphere and ionosphere. The model now calculates total temperature, instead of perturbation temperature about some specified global mean, global distributions of N(²D), N(4S) and NO, and a global ionosphere with distributions of O+,NO+, O2+, N2+, N+, electron density, and ion temperature as well as the usual fields of winds, temperature and major composition. Mutual couplings between the thermospheric neutral gas and ionospheric plasma occur at each model time step and at each point of the geographic grid. Steady state results for this first Eulerian model of the ionosphere, are presented for solar minimum equinox conditions. The calculated thermosphere and ionosphere global structure agrees reasonably well with the structure of these regions obtained from empirical models. This suggests that the major physical and chemical processes that describe the large-scale structure of the thermosphere and ionosphere have been identified and a self-consistent aeronomic scheme, based on first principles, can be used to calculate thermospheric and ionospheric structure considering only external sources.
Dialogic Public Relations and Resource Dependency: New Jersey Community Colleges as Models for Web Site Effectiveness

This study examines the organization–public communication of community college Web sites in light of two important bodies of public relations research: dialogic communication and resource dependency theory. Dialogue is important to understand because highly resource-dependant organizations like community colleges need to be able to effectively communicate with a variety of influential publics. This study seeks to better understand how organization and stakeholder information needs are met by effective Web design in highly resource dependant environments. This study reviews the current literature on community colleges, resource dependency theory, and dialogue; conducts a study of nineteen community college Web sites; and discusses the findings and directions for future research in public relations.
Growth Hormone Regulation of Sex-Dependent Liver Gene Expression

The liver is a primary target for the action of GH, a pituitary protein hormone that regulates a broad range of physiological processes, including long bone growth, fatty acid oxidation, glucose uptake, and hepatic steroid and foreign compound metabolism. GH exerts sex-dependent effects on the liver in many species, with many hepatic genes, most notably genes coding for cytochrome P450 (CYP) enzymes, being transcribed in a sex-dependent manner. Sex differences in CYP expression are most striking in rats and mice (up to 500-fold male-female differences), but are also seen, albeit to a much smaller degree, in humans, where they are an important determinant of the sex dependence of hepatic drug and steroid metabolism. This article examines the mechanisms whereby GH, via its sex-dependent temporal patterns of pituitary release, activates intracellular signaling leading to the sexually dimorphic transcription of CYPs and other liver-expressed genes. Recent findings implicating the GH-regulated transcription factor STAT5b (signal transducer and activator of transcription 5b), hepatocyte nuclear factors 3beta, 4alpha and 6, and sex differences in DNA methylation and chromatin structure in the sex-dependent actions of GH are reviewed, and current mechanistic models are evaluated.
Three faces of ageism: society, image and place

This paper elucidates and champions a spatiality perspective in social gerontology, by arguing that relationships between older people and the spaces and places they inhabit illuminate deeply-ingrained societal attitudes and values. The trilogy of society, image and place is explored through an interpretive reading of images and scripts in ‘successful ageing’ and ‘anti-ageing’ created and promoted by the booming ‘retirement industry’ in the United States. Six tropes are revealed in an interpretation of prevalent images of ‘Sunbelt Retirement Land’: geographic cornucopia, ageless selves, near perfection, the right stuff, down home living, and nomads of desire. This reading serves as a springboard in elaborating Cole's (1992) notion of bipolar ageism, as we vacillate between negative stereotypes of old age and positive elixirs, such as anti-ageing and agelessness, that are cloaked denials of decline, disease and death. The paper concludes with a series of troubling questions about the perpetuation and depth of ageism in society and culture.Every present day is determined by the images that are synchronic with it: each ‘now’ is the now of a particular recognizability. (Walter Benjamin, The Arcades Project, 1999: 462–63)
Coherent radar imaging based on compressed sensing

High-resolution radar images in the horizontal spatial domain generally require a large number of different baselines that usually come with considerable cost. In this paper, aspects of compressed sensing (CS) are introduced to coherent radar imaging. We propose a single CS-based formalism that enables the full three dimensional (3D)—range, Doppler frequency and horizontal spatial (represented by the direction cosines) domain—imaging. This new method can not only reduce the system costs and decrease the needed number of baselines by enabling spatial sparse sampling, but also achieves high-resolution in the range, Doppler frequency, and horizontal space dimensions. Using an assumption of point targets, a 3D radar signal model for imaging has been derived. By comparing numerical simulations with the fast Fourier transform (FFT) and maximum entropy (ME) methods at different signal-to-noise ratios (SNRs), we demonstrate that the CS method can provide better performance in resolution and detectability given comparatively few available measurements relative to the number required by Nyquist-Shannon sampling criterion. These techniques are being applied to radar meteor observations.
The design of switched eddy-current ironless motors

Proposed herein is a new assembly for a large and low speed high power density electric motor. The new design scheme is conceptually relevant to the functional nature of the electromagnetic hammer. This motor is considered to be of the switched repulsion motor class. However, it is distinguished in its ironless core assembly that provides desirable high power density characteristics. Using advanced power electronics and dynamic feedback control schemes, the motor is configured in two spinning shafts: one for the load; and the other for controls. The concept of the new design is tested on a simulator for its functionality and validity of control schemes.
Longleaf Pine (Pinus palustris P. Mill.) Restoration Using Herbicides: Overstory and Understory Vegetation Responses on a Coastal Plain Flatwoods Site in Florida, U.S.A.

A study was conducted on a Coastal Plain flatwoods site in Florida to determine the effects of common forestry herbicides on Longleaf pine seedling survival and growth and on the understory vegetation. Following removal of the overstory slash pine, five low-rate herbicide treatments were applied over the top of planted Longleaf pine seedlings to provide short-term understory vegetation control and accelerate seedling growth. The objective was to increase Longleaf pine growth by reducing the shrub competition while increasing the herbaceous ground cover. Despite causing reduction in seedling survival over the control treatment, imazapyr (0.21 ae kg/ha) resulted in the highest seedling growth (height and volume). The significant reduction of shrub cover, density, and height by imazapyr was believed to be responsible for the improved seedling growth in this treatment. Both hexazinone (0.56 ai kg/ha) and sulfometuron methyl (0.26 ai kg/ha) + hexazinone (0.56 ai kg/ha) treatments also reduced cover of Runner oak, a major shrub species, but the response was evident only 8 months after treatment. Although sulfometuron methyl (0.26 ai kg/ha) and sulfometuron methyl + hexazinone treatments did not result in any significant change in overall grass, forb, and shrub cover, both treatments resulted in greater Longleaf pine growth compared to the control. None of the herbicides significantly affected the major understory grasses and forbs. Overall, imazapyr provided the best desired results with significant increase in seedling growth and better control of shrub species with no significant effects on grass and other herbaceous species cover.
Unification of replication and transaction processing in three-tier architectures

In this paper we describe a software infrastructure that unifies replication and transaction processing in three-tier architectures and, thus, provides high availability and fault tolerance for enterprise applications. The infrastructure is based on the Fault Tolerant CORBA and CORBA Object Transaction Service standards, and works with commercial-off-the-shelf application servers and database systems. The infrastructure replicates the application servers to protect the business logic processing. In addition, it replicates the transaction coordinator which renders the two-phase commit protocol non-blocking and, thus, avoids potentially long service disruptions caused by coordinator failure. The infrastructure handles the interactions between the application servers and the database servers through replicated gateways that prevent duplicate requests from reaching the database servers. The infrastructure implements client-side automatic failover mechanisms, which guarantees that clients know the outcome of the requests that they have made. The infrastructure starts the transactions at the application servers, and retries aborted transactions, caused by process or communication failures, automatically on the behalf of the clients.
Composition and Vagueness

'Restricted composition' is a pair of commonsense claims. First, there are some composite objects, that is, objects with proper parts. Second, some objects jointly compose nothing. For example, a defender of restricted composition might say that my body is a composite object, having many atoms as parts. And she might deny that there is anything at all composed of my body and your nose and the planet Mercury. Commonsense credentials notwithstanding, restricted composition is controversial. This paper examines the most influential argument against it. I shall first show that the argument is inadequately defended. I shall then argue that its first premiss is false. This alone given the influence of this argument-is important. And, if I am right about why its first premiss is false, something even more important follows. What follows is a new way of understanding the question of whether composition is restricted and so a new focus for any future debates over composition's extent.
The Use of Video Cases in a Multimedia Learning Environment for Facilitating High School Students’ Inquiry into a Problem from Varying Perspectives

This study investigated the connection between the use of video cases within a multimedia learning environment and students’ inquiry into a socio-scientific problem. The software program was designed based on principles from the Cognitive Flexibility Theory (CFT) and incorporated video cases of experts with differing perspectives. Seventy-nine 10th-grade students in an urban high school participated in this study. After watching the expert videos, students generated investigative questions and reflected on how their ideas changed over time. This study found a significant correlation between the time students spent watching the expert videos and their ability to consider the problem’s perspectives as well as their ability to integrate these perspectives within their questions. Moreover, problem-solving ability and time watching the videos were detected as possible influential predictors of students’ consideration of the problem’s perspectives within their questions. Although students watched all video cases in equivalent ways, one of the video cases, which incorporated multiple perspectives as opposed to just presenting one perspective, appeared most influential in helping students integrate the various perspectives into their own thinking. A qualitative analysis of students’ reflections indicated that many students appreciated the complexity, authenticity, and ethical dimensions of the problem. It also revealed that while the majority of students thought critically about the problem, some students still had naive or simplistic ways of thinking. This study provided some preliminary evidence that offering students the opportunity to watch videos of different perspectives may influence them to think in alternative ways about a complex problem.
Effects of streptozotocin- and alloxan-induced diabetes mellitus on mouse follicular and early embryo development

Mice were made diabetic by intraperitoneal injection of streptozotocin or alloxan. Germinal vesicle breakdown in the ovarian follicles at 8 h after hCG in control animals (57%) was significantly greater than in streptozotocin-(24%) and alloxan-(42%) diabetic animals (P less than 0.001). This delay in oocyte maturation was reversible by in-vivo insulin administration to diabetic mice. A developmental delay was also found for embryos recovered from diabetic mice. This developmental delay extended into the 72 h in-vitro cultures. Compared to control embryos, those from alloxan- and streptozotocin-treated mice demonstrated marked impairment in development as assessed by (1) distribution of developmental cell stages at each observation period and (2) rates of development which increasingly diverged at each observation period. In diabetic mice treated with insulin in vivo, the percentage of 2-cell embryos recovered increased. Furthermore, in streptozotocin- and alloxan-animals treated with insulin, the rate of in-vitro development of embryos, as well as their developmental stage distribution improved. We therefore suggest that uncontrolled diabetes mellitus, as well as contributing to the development of congenital malformations, may deleteriously affect reproductive performance both before fertilization and at the very earliest gestational stages.
IMPLANTATION OF TESTOSTERONE COMPOUNDS IN CASES OF MALE EUNUCHOIDISM1

THE EFFECTIVENESS of an endocrine preparation is measured best by its capacity to restore normal function in a characteristic endocrinopathy caused by its deficiency. Eunuchoidism, or male hypogonadism, is the clinical state in which the primary deficiency resides in the testes, and therefore it represents an ideal clinical condition for testing the effectiveness of an androgenic substance. The synthesis of testosterone by Butenandt and Hanisch (I) and Rusicka et al. (2) made available for the first time a male hormone which could be tested clinically. Numerous observers have found this substance and its propionic acid ester to possess striking therapeutic value. The history and bibliography of this subject have been adequately reviewed in a recent paper by Vest and Howard (3) and also in a monograph by Moore and Koch (4). These reports have described the good results following parenteral injections of testosterone in an oily vehicle, 2 to 7 times weekly. In our own experience, most eunuchoids have, respo...
The 110-kD protein-calmodulin complex of the intestinal microvillus (brush border myosin I) is a mechanoenzyme.

The 110-kD protein-calmodulin complex (110K-CM) of the intestinal brush border serves to laterally tether microvillar actin filaments to the plasma membrane. Results from several laboratories have demonstrated that this complex shares many enzymatic and structural properties with myosin. The mechanochemical potential of purified avian 110K-CM was assessed using the Nitella bead motility assay (Sheetz, M. P., and J. A. Spudich. 1983. Nature (Lond.). 303:31-35). Under low Ca2+ conditions, 110K-CM-coated beads bound to actin cables, but no movement was observed. Using EGTA/calcium buffers (approximately 5-10 microM free Ca2+) movement of 110K-CM-coated beads along actin cables (average rate of approximately 8 nm/s) was observed. The movement was in the same direction as that for beads coated with skeletal muscle myosin. The motile preparations of 110K-CM were shown to be free of detectable contamination by conventional brush border myosin. Based on these and other observations demonstrating the myosin-like properties of 110K-CM, we propose that this complex be named "brush border myosin I."
Mechanism of arrhythmogenicity of the short-long cardiac sequence that precedes ventricular tachyarrhythmias in the long QT syndrome.

Abstract OBJECTIVES The purpose of this study was to investigate the electrophysiologic mechanism(s) that underlie the transition of one or more short–long (S-L) cardiac sequences to ventricular tachyarrhythmias (VTs) in the long QT syndrome. BACKGROUND One or more S-L cardiac cycles, usually the result of a ventricular bigeminal rhythm, frequently precedes the onset of VT in patients with either normal or prolonged QT interval. Electrophysiologic mechanisms that underlie this relationship have not been fully explained. METHODS We investigated electrophysiologic changes associated with the transition of a S-L cardiac sequence to VT in the canine anthopleurin-A model, a surrogate of LQT3. Experiments were performed on 12 mongrel puppies after administration of anthopleurin-A. Correlation of tridimensional activation and repolarization patterns was obtained from up to 384 electrograms. Activation–recovery intervals were measured from unipolar electrograms and were considered to represent local repolarization. RESULTS We analyzed 24 different episodes of a S-L sequence that preceded VT obtained from 12 experiments. The VT followed one S-L sequence (five episodes), two to five S-L sequences (12 episodes) and more than five S-L sequences (seven episodes). The single premature ventricular beats coupled to the basic beats were consistently due to a subendocardial focal activity (SFA). There were two basic mechanisms for the development of VT after one or more S-L sequences: 1) in 10 examples of a S-L sequence due to a stable unifocal bigeminal rhythm, the occurrence of a second SFA, which arose consistently from a different site, infringed on the pattern of dispersion of repolarization (DR) of the first SFA to initiate reentrant excitation; 2) in the remaining 14 episodes of a S-L sequence, a slight lengthening (50 to 150 ms) in one or more preceding cycle lengths (CLs) resulted in alterations of the spatial pattern of DR at key sites to promote reentry. The lengthening of the preceding CL produced differentially a greater degree of prolongation of repolarization at midmyocardial and endocardial sites compared with epicardial sites with consequent increase of DR. The increased DR at key adjacent sites resulted in the development of de novo zones of functional conduction block and/or slowed conduction to create the necessary prerequisites for successful reentry. CONCLUSIONS The occurrence of VT after one or more S-L cardiac sequences was due to well defined electrophysiologic changes with predictable consequences that promoted reentrant excitation.
Reflective arrayed waveguide grating multiplexer

A high-performance reflective arrayed waveguide grating multiplexer/demultiplexer designed for compatibility with silicon integrated circuit processing is described. The grating, folded by a flat reflecting surface, can be printed in a single-exposure field of a photolithographic stepper. Advanced plasma assisted deposition is used to prepare waveguides with very low loss and minimum birefringence. Multiplexers with 40 channels separated by 100 GHz show intrinsic insertion losses of -2.4 dB, channel uniformity less than 0.6 dB, and very low polarization dependent wavelength shift of 0.012 nm.
Berkeley v. Locke on Primary Qualities

Locke was once supposed to have argued that since the colours, sounds, odours, and other ‘secondary’ qualities things appear to have can vary greatly according to the state and position of the observer, it follows that our ideas of the ‘secondary’ qualities of things do not ‘resemble’ anything existing in the objects themselves. And Berkeley has been credited with the obvious objection that similar facts about the ‘relativity’ of our perception of ‘primary’ qualities show that they do not ‘resemble’ anything existing in the objects either, so that both ‘primary’ and ‘secondary’ qualities exist only ‘in the mind’. The falsity of this view of Locke has been amply demonstrated in recent years, but no corresponding revision has been made in what remains the standard interpretation of Berkeley's criticisms of Locke. His objections therefore appear to be based on misunderstanding and to be irrelevant to what is now seen to be Locke's actual view and his reasons for holding it. I think this account of Berkeley, like the old view of Locke, is a purely fictional chapter in the history of philosophy, and in this paper I try to show that Berkeley's criticisms involve no misunderstanding and amount to a direct denial of the view Locke actually held.
An Empirical Study of the Differential Market Reaction to Open-Market Stock Repurchase Announcements

Significant positive stock price reaction to stock repurchase announcements has been well documented in the finance literature. Most studies on repurchase focus on the average positive reaction; however, 30 percent of the repurchasing firms experience negative abnormal returns at announcement. This study examines the apparent heterogeneity in the stock price reaction to stock repurchase. The results show that the market reaction to repurchase announcements is determined by firm specific factors and is based on the overall costs and benefits analysis by the market of the stock repurchase program. The results are consistent with conventional signaling models and agency theories.
The role of the modern library in research evaluation

Abstract Research evaluation has taken on new significance in recent years due to two main developments. The first is the enormity of data and metadata concerning research outputs making it impractical for large scale subjective peer evaluation of multinational outputs spanning research fields, linguistic barriers and varying geographies. The second is the advent of the digital age in which the medium of communicating, storing and analyzing these data seems to be continuously evolving challenging even the most high tech librarians to keep pace. New electronic resources have led to the development of new analytical and visualization tools from both the public and private sectors and library and information professionals are increasingly required to use state-of-the-art systems to inform decision making at various levels of university and research institutions. In this paper, we present a series of integrated analytical and information management tools that support large and medium sized research institutions in developed countries and that are systematically being rolled out across developing regions that are embracing the shift towards the knowledge based economy and in which libraries are expected to play an important part. Examples from the Gulf region will be demonstrated and compared with other regions and recommendations for development will conclude the session.
No benefit to delaying pneumococcal polysaccharide vaccination in HIV-positive adults

To the Editor—The Advisory Committee on Immunization Practices (ACIP) recommends pneumococcal vaccination immediately after a diagnosis of human immunodeficiency virus (HIV) infection [1]. However, for patients with a CD4+ T-cell count of ≤ 200 cells/µL, the timing of pneumococcal vaccination, either immediately or 6–12 months after initiation of antiretroviral therapy (ART), is left to the discretion of the practitioner, owing to the lack of supporting evidence [2]. HIV-positive individuals not receiving ART commonly have high uncontrolled viral titers, abnormal distribution of B-cell populations, and poor responses to the pneumococcal polysaccharide (PPS) vaccine (PPV) [3]. Current pneumococcal vaccine recommendations by the ACIP for HIV-positive individuals are based on limited available data and would greatly benefit from additional clinical studies.
A physiological level of clenbuterol does not prevent atrophy or loss of force in skeletal muscle of old rats.

Supraphysiological levels of clenbuterol (CL) reduce muscle degradation in both young and old animals; however, these pharmacological levels induce side effects that are unacceptable in the elderly...
Capecitabine (C), oxaliplatin (OXP), and radiation (RT) in resectable esophagus cancer (EC): A phase II trial with gene expression profiling (GEP)

e15543 Background: Novel chemotherapy regimens in combination with RT aim to improve the pathologic complete response (pCR) in EC. Following our dose-finding phase I study, the present phase II neo...
ROOTWORM LARVAL MANAGEMENT IN CORN AND ITS IMPACT ON YIELD IN EASTERN SOUTH DAKOTA USING REGISTERED INSECTICIDAL MATERIALS, 2013

Northern and western corn rootworm (NCR/WCR) management efficacy trials were conducted to evaluate transgenic insect-resistant hybrids, liquid, and granular insecticide combination treatments near Bryant, Cavour, and Coleman in South Dakota. Plots consisted of four rows (∼50 ft long; spaced 30 inches apart) and were arranged in an RCBD with four replications. Granular insecticides were applied by using Nobel metering units or computer-assisted Smartbox insecticide delivery system. Planting-time liquid insecticides were applied using CO2-powered delivery systems individually mounted on …
An initial-boundary value problem of the nonlinear schrödinger equation

We present the PDE method to solve the initial‐ boundary value problem for the nonlinear Schrodinger equation (NLS). Under the assumption that boundary data (α is real) and initial data are smooth, we show that there exists a unique global solution.
Anticomplementary Power of Heparin

During the course of a study upon the effect of heparin on the coagulability of the blood, it was soon noted that the addition of 0.2 mg. of heparin completely inhibits hemolysis in a system consisting of 0.5 cc. of 5% washed sheep erythrocytes, 5 units of antisheep amboceptor and one unit of guinea-pig complement. When the complement was accurately titrated in a 1: 30 dilution, it was found that inhibition of hemolysis occurs when as little as 0.04 to 0.06 mg. of heparin was added to one unit of complement and that this inhibiting dose of the heparin varied little for different guinea-pig serums. It is of impor-
Learning Robotic Concepts with a 3R Lego NXT Robotic Arm

In this paper we present the use of a 3R Lego robotic arm for teaching basic robotic concepts. The Lego Mindstorms NXT kit is an affordable equipment that can be used to better visualize robotic concepts usually taught in classes. The 3R Lego Robot has 2 degrees of freedom and has been equiped with an accelerometer located at the end-effector to collect acceleration data in the x, y and z axes. Additionally, a gyroscope was placed at the joint for the up and down movement. This allowed for obtaining a plant for the 3R Lego Robot in order to understand the inverse and forward kinematics as well as the physical representation of Denavit- Hartenberg (DH) parameters, velocity manipulability ellipsoids and trajectory planning. This is essential and key in the study of plants that is relevant to everyday use in the industry and academia. This will allow professors at the university to teach more easily with hands-on approach. The Lego product is cost efficient and new programmable blocks can be built and incorporated into Simulink models. Therefore, this can be extended to more complex analysis and feedback control. This will lead to better analysis of the system and provide the students with higher education of what they have learned in class. Furthermore, students will be more competitive to obtain jobs in industry by combining theoretical with experimental approach. Traditionally, industry core concepts are not taught in the class and may be incorporated with the 3R Lego robot for resume building and skill set application. Some papers indicate the use of different programming languages for the Lego Robots; however, none of them have the capabilities and potential of Matlab and Simulink. Additionally, some others have presented simulation work to teach robotic-related concepts, but they either lack the hands-on approach or the hardware utilized is expensive. The importance of this study lies on understanding and implementing basic robotic concepts in Matlab and Simulink together with a 3R Lego robot. Therefore, a more complex Simulink model can be developed for controller design purposes. This paper describes a comparison of a simulation model versus a real life system for helping students to understand modeling system theories versus real world applications.
Subcortical Magnetic Resonance Imaging Changes in a Healthy Elderly Population; Stroke Risk Factors, Ultrasound, and Hemostasis Findings.

Magnetic resonance imaging (MRI) findings in a group of 60 ambulatory elderly individuals (average age, 75.8 yr) were characterized as normal (grade 0), periventricular changes only (grade 1 ). small punctate lesions (grade 2), and confluent or large (> 2 mm) punctate lesions (grade 3). Patients were characterized by stroke risk factors, cardiolipin antibodies, coagulation factors (fibrinogen and plasminogen activator inhibitor-1 ). and Doppler ultrasound findings in the carotid and middle cerebral arteries. Subcortical signal abnormalities were present in 62% (37 /60), relatively evenly distributed between grade 1 (18%), grade 2 (25%), and grade 3 (18%). There was no significant association between variables and MRI grade. These findings suggest that ischemia is not a major cause of MRI signal abnormalities in neurologically asymptomatic elderly individuals.
Antigen Presentation by CD1: Lipids, T Cells, and NKT Cells in Microbial Immunity

The discovery of molecules capable of presenting lipid antigens, the CD1 family, and of the T cells that recognize them, has opened a new dimensionin our understanding of cell-mediated immunity against infection. Like MHC Class I molecules, CD1 isoforms (CD1a, b, c and d) are assembled in the ER and sent to the cell surface. However, in contrast to MHC molecules, CD1 complexes are then re-internalized into specific endocytic compartments where they can bind lipid antigens. These include a broad scope of both self and foreign molecules that range from simple fatty acids or phospholipids, to more complex glycolipids, isoprenoids, mycolates and lipopeptides. Lipid-loaded CD1 molecules are then delivered to the cell surface and can be surveyed by CD1-restricted T cells expressing alphabeta or gammadelta T Cell Receptors (TCR). It has become clear that T cell-mediated lipid antigen recognition plays an important role in detection and clearance of pathogens. CD1a, b and c-restricted T cells have been found to recognize a number of lipid antigens from M. tuberculosis. CD1d-restricted T cells are the only CD1-restricted T cell subset present in mice, which lack the genes encoding CD1a, b and c. Evidence from experiments in CD1d-restricted T cell-deficient mice indicates that these cells play an important role in the immune response against awide range of pathogens including several bacteria, viruses and parasites. One subset of CD1d-restricted T cells in particular, invariant Natural Killer T (iNKT) cells, has been extensively studied. iNKT cells are characterized by the expression of a semi-invariant TCR composed of a strictly conserved alpha chain paired with a limited repertoire of beta chains. During infection, iNKT cells are rapidly elicited. Activated iNKT cells can produce a vast array of cytokines that profoundly affect both the innate and the adaptive arms of the immune response. In this review, we describe the pathways and mechanisms of lipid antigen binding and presentation by CD1 in detail, as well as the diverse roles played by CD1-restricted T cells in the context of microbial infection.
Kink in the intermodal supply chain: interorganizational relations in the port economy

The intermodal logistics supply chain is designed to move goods from the point of production to the point of consumption as quickly and as cheaply as possible. The ability to accomplish this objective has allowed for the wholesale geographic relocation and offshoring of basic manufacturing and assembly. As a chain of linked and integrated organizations characterized by sequential interdependence, interorganizational relations play a key role in determining the level of integration and seamlessness. Yet there is one critical interorganizational link in the chain that deviates from this vision. This is the relationship between the shipping container terminal and drayage trucking operations which is better described as a form of intermodal disintegration. The weakness in this link of the supply chain is explained by the divergent industrial structures and labor market conditions, the unique nature of the transaction, and the externalization of costs to subordinate workers.
Partial discharge detection of 3.3-kV motor by coil

Summary The coil is used to detect partial discharge (PD) in the 3.3-kV motor. Because of the noise issue, most studies detect PD of the motor at the power bus or at neutral. However, we use three coils inserted in the slot of three motor frames to detect PD. This conflicts with conventional thought. For safety, the motor frame is always grounded to the earth. In addition, most people think it is impossible to detect PD on the grounded motor frame. Most researchers say we measure noise or high-frequency current on the motor frame. In this paper, we design an experiment to prove that what we measure is the induction magnetic field of PD. From the amplitude variation of the PD signal, the imperfect motor can be identified. Moreover, by measuring the PD signal and the three-phase 60-Hz waveform, we can determine the phase at which PD occurs. Copyright © 2016 John Wiley & Sons, Ltd.
Synchronous isolated ipsilateral salivary gland metastasis from a primary breast cancer – A case report

The most common sites of distant metastasis for breast are the lungs, liver, bones and brain. Here we report an extremely rarepresentation of isolated salivary gland metastasis from primary breast cancer, indicating advanced stage of breast disease and signof poor prognosis. The case emphasizes the need for a thorough workup for distant metastatic disease in patients diagnosed withinvasive breast cancer.
Carbohydrate–Polypeptide Contacts in the Antibody Receptor CD16A Identified through Solution NMR Spectroscopy

Asparagine-linked carbohydrates (N-glycans) are common modifications of eukaryotic proteins that confer multiple properties, including the essential stabilization of therapeutic monoclonal antibodies. Here we present a rapid and efficient strategy for identifying N-glycans that contact polypeptide residues and apply the method to profile the five N-glycans attached to the human antibody receptor CD16A (Fc γ receptor IIIA). Human embryonic kidney 293S cells expressed CD16A with 13CU-labeled N-glycans using standard protein expression techniques and medium supplemented with 3 g/L [13CU]glucose. Anomeric resonances on the protein-linked N-acetylglucosamine residue at the reducing end of the glycan are particularly well suited to studies of multiply glycosylated N-glycoproteins because only one reducing end and nitrogen-linked residue is present in each N-glycan. Correlations between anomeric 1H1 and 13C1 nuclei on the reducing end residue generate crosspeaks in a conventional two-dimensional heteronuclear si...
Minimum-Time 2 1/2D Navigator for Autonomous Mobile Robot

Abstract A hierarchical controller is consid-dered with three levels of control: Planner, Navigator, and Pilot functioning upon a unified hierarchical knowledge base. Minimum-time path is being navigated within 2 1/2D world with obstacles. An algorithm of “nested modified dynamic programming” is applied to find a desirable trajectory of notion. Paper is illustrated by results of computer simulation for a number of scenarios based upon various outdoor landscapes.
The Complexity of Color and the Religion of Whiteness

African American’s self-consciousness about their skin color is closely related to their engagement with whiteness in a world in which whiteness has been the dominant religion. After all, self-conception is intersubjective. We come to know ourselves, in part, in response to our perception of others and, in turn, as reflections of other people’s perceptions of us. Du Bois’s aphoristic reflection on “double consciousness” is salient for just this reason (Du Bois, 1903).
The Relationality of Everyday Life: The Unfinished Journey of Relational Psychoanalysis

Building on the insights embodied in Stephen Mitchell’s critiques of the developmental tilt and the metaphor of the baby, this paper aims to further illuminate the limitations of theoretical models rooted in infantile prototypes and to point relational theory toward a more thoroughgoing understanding of the contextuality and relationality of every facet of our lives. In its examinations of both the mother–infant interaction and the intricacies of the analytic relationship, the relational turn has yielded deep insights into the reciprocal, two-person causal sequences that characterize the development and dynamics of personality. But in the massive zone of living that occurs outside the nursery or the consulting room—the countless interactions and experiences of everyday life—relational theory has made less of a contribution, implicitly relying on an older psychoanalytic model in which these events of daily life reflect or express inner dynamics, rather than highlighting how daily life experiences continue ...
Examining participation and engagement in a microblogging-supported college-level hybrid course

AbstractThis study sought to understand student participation and engagement in a microblogging-supported college-level hybrid course. Using a case study design, the researchers examined how students participated and engaged in a variety of microblogging-supported instructional activities, including backchanneling, exploration, discussion, and live chat activities. Students were asked to report their perception of their learning experience. Our study suggested that students participated actively in the microblogging-based activities, while challenges remained as well. The degree of participation and engagement varied considerably depending on the type of instructional activity. Despite that students perceived all activities positively, our analyses of student tweets showed that sustained participation and engagement with a high-level of interactivity was rarely achieved among the data.
Assessing the Impact of Case Management on Medicaid Clients with Chronic Diseases

State Medicaid programs increasingly use case management to manage enrollees with chronic conditions who may become cost intensive for the program. The authors examined the impact of Alabama Department of Public Health (ADPH)'s case management on care expenditures for Medicaid enrollees with various chronic diseases, over 2011 to 2014. The authors matched case-managed enrollees with three controls per case using health conditions and sociodemographics. Thereafter, the authors used a quasi-experimental approach to estimate how per-member-per-month costs changed following case management. Case -management appeared to result in program savings, driven largely by inpatient and emergency department cost-savings. There was noticeable variation in savings for members with different chronic conditions.
Academic collaborations: Linking the role of the liaison/embedded librarian to teaching and learning

Building partnerships with faculty can be a challenging process for embedded librarians. After defining the essential role of an embedded librarian, this article chronicles the systematic process o...
Correlation of NDE Parameters with Fatigue Lifetime of Aircraft Adhesive Bonds

Various NDE methods and techniques have recently been developed to characterize adhesive bonds. These techniques simply detect voids. However, information about the presence of voids does not necessarily reflect the strength of the joints [1]. Moreover, it has been shown by Schonhorn [2] that the static failure load of joints is not largely affected by the size of a defect. Although this may be true for monotonic loading, it may not be the case under fatigue loading which is more representative of the in-service conditions. Under fatigue loading, inherent voids, cracks etc. can coalesce and form a considerably larger flaw which will eventually consume a very large portion of the bonded area. Fatigue failures account for a large number of in-service material failures of joints. Therefore, it is important to relate the size and number of defects detected by NDE methods to a quantity such as fatigue lifetime; this is the focus of the present work.
The heel in sport

This article describes pain that occurs in both the posterior and inferior heels. Various examples of athletes with these kinds of pain are discussed. The different types of heel pain are explored, and the article stresses the need for conservative care.
Pharmacokinetic Imaging: A New Concept in Functional Imaging

Pharmacokinetics is the study of the time course of drug distribution and metabolism in body fluids and tissues [1]. In nuclear medicine, the in vivo behavior of radiodiagnostic agents is often used to indicate an organ’s or organ system’s primary function, for instance, ventilation and perfusion of the lungs or cellular function by measurement of uptake and elimination of a tracer substance. The functional image was introduced as a kinetic parametric analysis method where regional rate constants were portrayed as images of regional function [2–4]. Recently the term functional image has been more widely used to describe other functions, including anatomic motion, perfusion, and ventilation [5–8].