cssi/SciSciGPT-SciSciNet huggingface dataset:
The solution structure and dynamics of the pleckstrin homology domain of G protein-coupled receptor kinase 2 (beta-adrenergic receptor kinase 1). A binding partner of Gbetagamma subunits.

Abstract The solution structure of an extended pleckstrin homology (PH) domain from the β-adrenergic receptor kinase is obtained by high resolution NMR. The structure establishes that the β-adrenergic receptor kinase extended PH domain has the same fold and topology as other PH domains, and there are several unique features, most notably an extended C-terminal α-helix that behaves as a molten helix, and a surface charge polarity that is extensively modified by positive residues in the extended α-helix and the C terminus. These observations complement biochemical evidence that the C-terminal portion of this PH domain participates in protein-protein interactions with Gβγ subunits. This suggests that the C-terminal segment of the PH domain may function to mediate protein-protein interactions with the targets of PH domains.
Development of a novel strain sensor using nanotube-based materials with applications to structural vibration control

In many structural vibration control applications, strain sensors play a key role in the design and implementation of the vibration controller. Different types of sensors are commercially available, among which is the poled polyvinylidene difluoride (PVDF), an attractive sensor for large bandwidths and low costs. Despite such attractive features, PVDF-based sensors have limited use due to their low efficiency (mechanical energy to electrical energy conversion factor). To remedy this, nanocrystals and nanostructures have been recently cited as candidate materials that can be engineered to exhibit enhanced or entirely new properties for use in different applications. Particularly, carbon nanotubes (CNTs) have raised considerable interest in the scientific community due to their size and wide range of outstanding material properties. Given the moduli and strength values of CNTs, they are ideal filler materials for high performance (polymer) composite materials with unbeatable modulus-to-weight and strength-to-weight ratios -- the attributes that are essential for structural vibration control of a wide variety of industrial equipment and systems. Along this line of reasoning, this paper undertakes the development and implementation of a novel sensor paradigm based on proper fusion of CNTs with PVDF materials.
Regional distribution of forest height and biomass from multisensor data fusion

[1] Elevation data acquired from radar interferometry at C‐band from SRTM are used in data fusion techniques to estimate regional scale forest height and aboveground live biomass (AGLB) over the state of Maine. Two fusion techniques have been developed to perform post‐processing and parameter estimations from four data sets: 1 arc sec National Elevation Data (NED), SRTM derived elevation (30 m), Landsat Enhanced Thematic Mapper (ETM) bands (30 m), derived vegetation index (VI) and NLCD2001 land cover map. The first fusion algorithm corrects for missing or erroneous NED data using an iterative interpolation approach and produces distribution of scattering phase centers from SRTM‐NED in three dominant forest types of evergreen conifers, deciduous, and mixed stands. The second fusion technique integrates the USDA Forest Service, Forest Inventory and Analysis (FIA) ground‐based plot data to develop an algorithm to transform the scattering phase centers into mean forest height and aboveground biomass. Height estimates over evergreen (R 2 = 0.86, P < 0.001; RMSE = 1.1 m) and mixed forests (R 2 = 0.93, P < 0.001, RMSE = 0.8 m) produced the best results. Estimates over deciduous forests were less accurate because of the winter acquisition of SRTM data and loss of scattering phase center from tree‐surface interaction. We used two methods to estimate AGLB; algorithms based on direct estimation from the scattering phase center produced higher precision (R 2 = 0.79, RMSE = 25 Mg/ha) than those estimated from forest height (R 2 = 0.25, RMSE = 66 Mg/ha). We discuss sources of uncertainty and implications of the results in the context of mapping regional and continental scale forest biomass distribution.
CP-Law Statements as Vague, Self-Referential, Self-Locating, Statistical, and Perfectly in Order

I propose understanding CP-law statements as statements that assert the existence of vague statistical laws, not by fully specifying the contents of those laws, but by picking them out via a description that is both self-referential and self-locating. I argue that this proposal validates many common assumptions about CP-laws and correctly classifies many examples of putative CP-laws. It does this while avoiding the most serious worries that motivate some philosophers to be skeptical of CP-laws, namely the worry that they lack non-trivial truth conditions and that it is impossible for empirical evidence to disconfirm them.
Studies on partially purified phenylalanine hydroxylase

Abstract 1. 1. The phenylalanine hydroxylase system has been partially purified from rat livers and has been shown to consist of two protein fractions, a labile fraction which is found only in the liver and a more stable fraction which is also found in kidney and heart. 2. 2. DPN is involved catalytically only when an aldehyde or an alcohol is present. 3. 3. DPNH is the actual cofactor. 4. 4. Ferrous ion appears to be an integral part of the enzyme system. 5. 5. The over-all reaction could not be separated into two steps and no intermediates could be demonstrated.
Incidence of Herpes Zoster Ophthalmicus: Results from the Pacific Ocular Inflammation Study

Purpose To provide a population-based estimate of the incidence of herpes zoster ophthalmicus (HZO) with comparisons across racial, sex, and age groups, as well as to estimate the frequency of postherpetic neuralgia (PHN). Design Retrospective, population-based cohort study. Participants All patients enrolled in the Kaiser Permanente Hawaii health plan during the study period (N = 217 061). Methods All patient encounters between January 1, 2006, and December 31, 2007, in the electronic medical record of Kaiser Permanente Hawaii were queried for International Classification of Diseases, 9th edition (ICD-9) codes corresponding to HZO. Charts were reviewed to confirm a diagnosis of HZO and to collect information about specific ocular manifestations. Demographic data and information on PHN were collected electronically. Incidence rates were calculated per 100 000 person-years for the entire population and for age-, sex-, and race-specific subgroups. Main Outcome Measures Clinical diagnosis of HZO during the study period. Results A total of 134 cases of HZO were identified in this population of 217 061 people. The overall incidence was 30.9 per 100 000 person-years (95% confidence interval [CI], 25.9–36.6). The incidence rate for the population aged ≥65 years was 104.6 per 100 000 person-years (95% CI, 79.0–135.9), approximately 5 times the remainder of the population ( P P = 0.007). Twenty-one percent of patients with HZO developed PHN. Older age and HZO with keratitis, conjunctivitis, or uveitis were found to be risk factors for PHN. Conclusions This study provides a population-based estimate of HZO and highlights differences across various age and racial groups. It also suggests that demographic characteristics may be useful in determining the risk of developing HZO. Financial Disclosure(s) The author(s) have no proprietary or commercial interest in any materials discussed in this article.
The presence of 4-selenouridine in Escherichia coli tRNA.

Abstract We have previously shown that tRNA from Escherichia coli grown in [ 75 Se]selenite contains [ 75 Se]. When such [ 75 Se]tRNA was enzymatically digested to nucleosides and analyzed by cation-exchange chromatography on Aminex A-6, four peaks of 75 Se were obtained. One of these co-chromatographed with authentic 4-selenouridine. When this peak was lyophilized and chromatographed on a cellulose thin layer, the bulk of the 75 Se again co-migrated with authentic 4-selenouridine, thus providing the first identification of a naturally-occurring selenonucleoside.
Recall of rapidly presented random chess positions is a function of skill

A widely cited result asserts that experts’ superiority over novices in recalling meaningful material from their domain of expertise vanishes when they are confronted with random material. A review of recent chess experiments in which random positions served as control material (presentation time between 3 and 10 sec) shows, however, that strong players generally maintain some superiority over weak players even with random positions, although the relative difference between skill levels is much smaller than with game positions. The implications of this finding for expertise in chess are discussed and the question of the recall of random material in other domains is raised.
Narrative Accounts of Research for Teaching the Processes of Science

To enhance learning about the processes of scientific thinking, this paper suggests that students read and write summaries of narrative accounts of research. Background is provided on the nature of narrative, learning from narrative versus expository texts, surface and deep approaches to studying, and the advantages of writing over testing for assessment. A list of narrative sources is provided.
Word of mouth, brand loyalty, acculturation and the American Jewish consumer

Purpose – The intent of this article is to explore if there is a difference between American Jewish consumers and American non‐Jewish consumers in the use of word of mouth and brand loyalty in response to the purchase of durable goods (automobiles). Additionally, this article aims to explore if there is a difference in the use of word of mouth and brand loyalty among American Jews with differing levels of acculturation.Design/methodology/approach – This article utilizes survey data obtained from over 400 respondents with analysis performed using regression and chi‐squared analysis.Findings – This study shows no significant difference in brand loyalty and word of mouth between all American Jews and American non‐Jews, however, a significant difference between highly acculturated American Jews and low‐acculturated American Jews was found.Practical implications – The article helps firms plan their marketing strategy in terms of how they will utilize word of mouth where American Jewish consumers comprise a sig...
Outcome of very low birth weight infants with histopathologic chorioamnionitis

Abstract Objective: To determine neonatal outcome at 7 months of corrected age in very low birth weight (VLBW) infants with placental chorioamnionitis. Methods: We conducted a cohort study of 287 VLBW infants delivered as a result of preterm premature rupture of membranes (PROM) or preterm labor. Control subjects ( n = 123) had placentas with absent umbilical cord inflammation and absent or low-grade membrane inflammation. Case subjects ( n = 164) had moderate membrane inflammation or any umbilical cord inflammation. Neonatal and 7-month outcomes were compared. A power analysis showed that 98 total subjects were needed to reject the two-sided null hypothesis with a difference in mean Bayley index scores of at least 8. Results: Infants in the study group had significantly more preterm PROM, antenatal antibiotics, lower birth weight, lower gestational age, longer duration of ruptured membranes, and clinical chorioamnionitis. Intraventricular hemorrhage occurred more commonly in infants with placentas demonstrating chorioamnionitis (relative risk = 1.6, 95% confidence interval 1.1, 2.4, P = .013). One hundred sixty-seven (69%) of the 243 surviving infants had 7-month follow-up. There was no difference between cases and controls in mean Bayley mental developmental index (93 compared with 90, P = .25), psychomotor developmental index (89 compared with 90, P = .68), or in the number of infants that were developmentally delayed. Conclusion: Despite a higher frequency of intraventricular hemorrhage, no difference in developmental scores was detected at 7 months of corrected age in VLBW infants with histologic chorioamnionitis.
The course of postdisaster psychiatric disorders in directly exposed civilians after the US Embassy bombing in Nairobi, Kenya: a follow-up study.

Purpose While disasters are common in Africa, disaster studies in Africa are underrepresented in the published literature. This study prospectively examined the longitudinal course of psychopathology, coping, and functioning among 128 directly exposed Kenyan civilian survivors of the 1998 US Embassy bombing in Nairobi.
Strain Dependence of Bonding and Hybridization Across the Metal-Insulator Transition of VO2

Soft x-ray spectroscopy is used to investigate the strain dependence of the metal-insulator transition of VO${}_{2}$. Changes in the strength of the V $3d$--O $2p$ hybridization are observed across the transition and are linked to the structural distortion. Furthermore, although the V-V dimerization is well described by dynamical mean-field theory, the V-O hybridization is found to have an unexpectedly strong dependence on strain that is not predicted by band theory, emphasizing the relevance of the O ion to the physics of VO${}_{2}$.
Vascular closure devices and the risk of vascular complications after percutaneous coronary intervention in patients receiving glycoprotein IIb-IIIa inhibitors

Vascular closure devices offer advantages over traditional means of obtaining hemostasis after percutaneous coronary intervention (PCI) in terms of patient comfort and time to ambulation. We investigate whether such devices also reduce the risk of vascular complications in selected patient populations. We conducted a retrospective analysis of all patients who underwent PCI at our institution between January 1998 and December 1999. Of 3,151 consecutive patients, 3,027 were eligible to receive vascular closure devices. Of these, 1,485 received a closure device and 1,409 received glycoprotein IIb-IIIa antagonists. The overall vascular complication rate, as defined by the need for surgical repair or transfusion, or the development of arteriovenous fistula, pseudoaneurysm, or large hematoma, was 4.20%. By univariate analysis, the use of closure devices was associated with a lower vascular complication rate (3.03% vs 5.52%; p = 0.002) and a shorter length of hospital stay (2.77 vs 3.97 days, p <0.001). Multivariate analysis showed a significant reduction in vascular complications with closure devices (odds ratio 0.59, p = 0.007). For the subgroup of patients receiving glycoprotein IIb-IIIa antagonists, the use of closure devices was associated with an even more pronounced reduction in the risk of vascular complications (odds ratio 0.45, p <0.008). Thus, the use of closure devices in selected patients undergoing PCI is associated with a low rate of vascular complications and decreased length of stay. This benefit was most marked for patients receiving glycoprotein IIb-IIIa antagonists.
The pathway of glucose oxidation in Corynebacterium creatinovorans.

Abstract Aqueous suspensions of Corynebacterium creatinovorans oxidized glucose rapidly with an oxygen uptake and CO 2 formation of two moles per mole of glucose oxidized. Anaerobically, the cells did not ferment glucose. The fluid withdrawn at different intervals during the oxidation of glucose by C. creatinovorans contained sedoheptulose, ribulose, ribose, gluconic acid, ketogluconic and, α-ketoglutaric acid, and traces of other unidentified keto acids. This is demonstration that glucose was oxidized by phosphorylative oxidation and by direct oxidation.
Direct immunofluoresence in vasculitic neuropathy: Specificity of vascular immune deposits

In suspected vasculitic neuropathy, vasculitis is demonstrated in only 30% of superficial peroneal nerve (SPN)/peroneus brevis muscle (PBM) specimens. Pathologic predictors of vasculitis are thus needed for non-diagnostic cases. Immune deposits in epineurial vessels have an established sensitivity but unknown specificity. In this study we assessed specificity using direct immunofluorescence (DIF) in SPN/PBM biopsies for suspected vasculitic neuropathy. Biopsies from 13 patients with vasculitis, 13 without vasculitis, and 6 with diabetic radiculoplexus neuropathy (DRPN) were stained for immunoglobulin G (IgG), IgM, and complement 3 (C3), and analyzed in a blinded manner. Vascular immunoglobulin or C3 deposits occurred in 12 of 13 nerve or muscle biopsies (11 of 13 nerves, 5 of 13 muscles) in vasculitis vs. 1 of 13 (1 of 13 nerves, 0 of 13 muscles) in controls (P = 0.00003). Specificity was 92%. For DRPN, vascular immune deposits occurred in 5 of 6 nerves or muscles (4 of 6 nerves, 1 of 5 muscles), similar to vasculitis but significantly different from controls. Epineurial/perimysial vascular deposits of immunoglobulin/C3 by DIF are a specific marker of vasculitic neuropathy.
Relation of Invertebrate Death Assemblages to Living Benthic Communities in Recent Carbonate Sediments Along Eastern Yucatan Coast: ABSTRACT

The fidelity of the fossil record for paleoecological studies often is questioned. This investigation attempted to determine how well communities of living benthic organisms are represented by the assemblages of dead remains accumulating in the sediment, i.e., future fossil assemblages. Fifty quantitative samples were collected with a diver-operated suction dredge from various shallow-marine environments near Isla Cancun and Isla Contoy, Quintana Roo, Mexico. Virtually all the geologically preservable megafaunal remains in the sediment consisted of mollusks, and 290 molluscan species were identified in the samples. Although nearly three fourths of the species were collected only as dead shells, almost all live individuals were represented by dead shells of their species in the same sample. A series of Q-mode and R-mode cluster analyses, utilizing 5 different similarity coefficients and data based on the presence or absence and relative abundances of species, demonstrates that the same general associations of samples and organisms occur, whether living animals or dead remains only are considered. Chi-square association tests between pairs of samples collected 5 m apart reveal that the death assemblages in both samples of each pair are similar, whereas the living communities are not. The death assemblages apparently reflect the in-place accumulation of remains of living benthic communities during sedimentation as patchily distributed populations of organisms migrate across the bottom, leaving a record of their mortality behind them in the sediment. End_of_Article - Last_Page 777------------
Northern ancestry for the Goochland terrane as a displaced fragment of Laurentia

The ancestral position of the Goochland terrane, an isolated block containing Mesoproterozoic crust in the Appalachian Piedmont of eastern Virginia, during Grenvillian orogenesis has direct bearing on the breakup of Rodinia. Ages, lithology, geochemistry, and Pb and Nd isotope compositions of the Montpelier Anorthosite and State Farm Gneiss of the Goochland terrane allow correlation with the Grenvillian Roseland Anorthosite and associated igneous suites of the Blue Ridge farther west in Virginia. In contrast, extensive metapelites, which underwent Devonian metamorphism and intrusion, and amphibolites of the Goochland terrane lack equivalents in the Blue Ridge. Dextral slip faults, which bound the Goochland terrane, as well as dextral faults farther north, suggest large-scale translation prior to late Paleozoic reaccretion. Ages of extension-related A-type granitoids within the Virginia Blue Ridge (735-680 Ma) suggest physical separation from compositionally similar granitoids in the Goochland terrane (630-588 Ma), Reading Prong (602 Ma), and Manhattan Prong (563 Ma). Pre-Iapetan restoration of the Goochland terrane northeastward of the Blue Ridge and outboard of the Reading Prong accounts for its affinities to the Blue Ridge (unique anorthosites), Manhattan Prong (abundant amphibolites), and Reading Prong (ca. 600 Ma magmatism). Thus similar to the translation of Madagascar out of Africa, the Goochland terrane was rifted from Laurentia, marooned in oceanic crust, and then dextrally translated southward ∼500 km prior to late Paleozoic reaccretion. Documentation of large-scale dextral translation of eastern Laurentia relative to its fragments and other cratons during the Neoproterozoic and Paleozoic may assist in locating far-traveled pieces of the Grenville orogen for reconstruction of Rodinia.
Role of coherent structures on reynolds stresses in a 2‐D bubble column

The hydrodynamics of two-dimensional bubble columns operated in various flow regimes are studied using particle image velocimetry. Both averaged velocity profiles and Reynolds stress profiles are obtained and discussed in relation to large-scale structures present in the flow. The normal stresses, dominated by large-scale structures, are an order of magnitude higher than the shear stress. It is found that the contribution from the bubbles to the shear to the normal stresses is negligible. A time series of the flow field is studied, demonstrating that the flow could be split into a low-frequency contribution due to the vortical structures and a high-frequency fluctuating part. The latter gives rise to flat normal stress profiles, and the former is responsible for the original form of the normal stress profiles. The shear stress in the smaller columns investigated can be related to the averaged vertical velocity profile according to a Boussinesq approximation. Data on the eddy viscosity are presented.
Pool Revenue Sharing, Team Investments, and Competitive Balance in Professional Sports A Theoretical Analysis

Using a contest model of a professional sports league, we show that pool revenue sharing has a negative effect on total expenditure for player talent. There are ``moral hazard'' problems with lower revenue teams in that they may pocket the money they receive from the pool without increasing talent investments. Based on four alternative measures of competitive balance, we find that pool revenue sharing increases the variance of expected winning percentages for a match and thus reduces the degree of competition in the league. Policy recommendations that combine pool revenue sharing with the requirement of a minimum payroll on players are shown to be procompetitive.
Guidelines for high-performance electronic package interconnections-a simple approach

Guidelines are introduced for designing high-performance interconnections in high-density electronic packages. Three electrical constraints (namely a transient response requirement of the system, an undershoot requirement at the load end of the driven line, and a crosstalk requirement at the load end of the quiet line) relate the design parameters. A simple design algorithm is discussed that relates design parameters. This method is valid for small-capacitive-loads, low-loss lines, and loosely-coupled lines. Ranges for parameters are specified within which the approach is valid. Design curves are presented for this simplified design method. To increase packaging density line cross sections and spacings must be reduced. As a result line loss and line coupling increase. The simple design guidelines presented here show that these trends need not jeopardize circuit performance if s/h/spl ges/0.8 with C/sub L//spl les/0.3 and r/sub D//spl ges/0.45. For systems with parameters outside these ranges, other approaches are needed.
Performance of MFSK/FFH spread spectrum multiple-access communication system with selection diversity

A study is made of the performance of a fast frequency hopped spread spectrum multiple-access communication system with M-ary frequency-shift keying modulation. The system operates through a frequency-selective slow-fading Rayleigh channel coupled with other-user interference and additive white Gaussian noise. Signals received through multiple antennas are combined by means of selection diversity, namely, the output of the antenna which has a path giving the largest path gain is selected to generate the detection statistics. It is shown that the system performance can thus be improved significantly. >
Studies in the history of probability and statistics XLIX On the Matérn correlation family

SUMMARY Handcock & Stein (1993) introduced the Matern family of spatial correlations into statistics as a flexible parametric class with one parameter determining the smoothness of the paths of the underlying spatial field. We document the varied history of this family, which includes contributions by eminent physical scientists and statisticians.
RNA Graph Partitioning for the Discovery of RNA Modularity: A Novel Application of Graph Partition Algorithm to Biology

Graph representations have been widely used to analyze and design various economic, social, military, political, and biological networks. In systems biology, networks of cells and organs are useful for understanding disease and medical treatments and, in structural biology, structures of molecules can be described, including RNA structures. In our RNA-As-Graphs (RAG) framework, we represent RNA structures as tree graphs by translating unpaired regions into vertices and helices into edges. Here we explore the modularity of RNA structures by applying graph partitioning known in graph theory to divide an RNA graph into subgraphs. To our knowledge, this is the first application of graph partitioning to biology, and the results suggest a systematic approach for modular design in general. The graph partitioning algorithms utilize mathematical properties of the Laplacian eigenvector (µ2) corresponding to the second eigenvalues (λ2) associated with the topology matrix defining the graph: λ2 describes the overall topology, and the sum of µ2′s components is zero. The three types of algorithms, termed median, sign, and gap cuts, divide a graph by determining nodes of cut by median, zero, and largest gap of µ2′s components, respectively. We apply these algorithms to 45 graphs corresponding to all solved RNA structures up through 11 vertices (∼220 nucleotides). While we observe that the median cut divides a graph into two similar-sized subgraphs, the sign and gap cuts partition a graph into two topologically-distinct subgraphs. We find that the gap cut produces the best biologically-relevant partitioning for RNA because it divides RNAs at less stable connections while maintaining junctions intact. The iterative gap cuts suggest basic modules and assembly protocols to design large RNA structures. Our graph substructuring thus suggests a systematic approach to explore the modularity of biological networks. In our applications to RNA structures, subgraphs also suggest design strategies for novel RNA motifs.
Race, Class, and Labor Markets: The White Working Class and Racial Composition of U.S. Metropolitan Areas

Abstract Because divisions caused by racism are presumed to weaken the working class and because racism is more apparent in local areas with relatively large Black populations, labor market proportion Black is expected to be positively associated with class inequality among Whites. However, Black population size has also been systematically linked to White privilege across a wide array of indicators. In this article, I test the effects of labor market proportion Black on Black–White and class inequality for men and women using hierarchical linear models with 1990 data from U.S. metropolitan areas. The analysis demonstrates that labor markets with larger Black populations have greater class inequality among White men (not women), but also greater relative White-over-Black advantages across class levels, male and female—and these race effects are substantially larger than the class effects. The results are thus consistent with a contradictory position for the White working class with regard to racism.
A novel Ka-band 1 to 8 power divider/combiner

In this paper, a 1-to-8 traveling wave power divider/combiner design at Ka-band is presented. This power divider/combiner is composed of eight units coupling power from rectangular waveguide to microstrip lines. Coupling is achieved through longitudinal slots in the broad wall of the waveguide. Shorting posts inside the waveguide are used to adjust the coupling values. Experiments on the eight-way passive divider/combiner back-to-back design demonstrates a minimum overall insertion loss of 1.8 dB at 32.5 GHz with a 3 dB bandwidth of 15%.
Technology transfer of Network Therapy to community-based addictions counselors.

Abstract This paper describes a technology transfer initiative in which Network Therapy (NT), a substance abuse treatment that utilizes peer and family support, was disseminated to a cohort of addictions counselors located in an outpatient community-based addictions treatment center. Training methods included a didactic seminar, role-playing, use of videotaped illustrations, and clinical supervision, and are described in detail. Counselors then implemented the NT approach with a sample of cocaine-abusing patients ( N = 10) who were being treated concurrently with the standard program provided by the treatment setting. NT patients were compared by chart review with a cohort of cocaine abusers who received community treatment-as-usual (TAU) ( N = 20). The groups did not differ on demographic variables or the amount of TAU received at the community program. However, NT patients had significantly less positive urinalyses than TAU patients, though they were not significantly different in terms of treatment retention. Implications for technology transfer are discussed.
Neutrophil adhesive dysfunction in thermal injury: the role of fibronectin.

We examined neutrophil substrate adherence in 19 subjects with burns involving l^o-SS^b of their body surface area. Within 24 h of injury, neutrophils from burn patients demonstrated a 50^0 reduction in adhesion to both gelatin and plastic substrates when stimulated with N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP), phorbol myristate acetate, and calcium ionophore A23187. Neutrophil substrate adherence examined as long as two weeks after burn injury remained abnormal. Neutrophils, from burn patients, stimulated with FMLP, phorbol myristate acetate, and calcium ionophore A23187 demonstrated a 51^0, 37^0, and 45^0 decrease, respectively, in release of immunoreactive fibronectin compared with control neutrophils. In neutrophils from burn patients there was a 31^0 reduction in total neutrophil-associated fibronectin compared with controls. The decrement in release and total cellular content of fibronectin in neutrophils from burn patients did not change when reexamined on day 7 after injury. The magnitude and time course of alterations in the cellular content and release of fibronectin correlate with adhesive dysfunction after burn injury.
Tales From the Front Line: Teachers’ Responses to Somali Bantu Refugee Students

This qualitative study identifies the ways in which teachers in an urban school district responded to the specialized educational needs of Somali Bantu refugee students who have recently been relocated to the United States and who have had limited and interrupted access to education prior to their enrollment in public schools in the United States. The article identifies the institutional obstacles teachers in Central City1 high schools faced in general during the 2007—2008 school year and then highlights the different types of responses employed by native U.S.-born teachers when working with their Somali Bantu students.
Recycled Structural Papers: New Approaches for Material Property Improvement

Recycling of fiber into structural papers for the corrugated container industry, paper tubes, cartonboard or other paperboard with structural performance needs may require enhancement of properties through changes in the papermaking process. The loss of bonding capability, coupled with a degree of fiber shortening and fiber inflexibility, reduces the utility of recycled fiber and thus their competitiveness with their virgin counterparts. Traditional means for enhancing performance includes addition of starches or other binders, mechanical beating, or heat treatments. Other means for achieving heightened performances are reviewed which include alternative drying technologies, optimal placement of fibers within the paper sheet and forming technologies that provide structural enhancement. KEYWORDS: Fibers. fractionation, swelling, drying methods, fiber bonding. fiber alignment, pulp molding.
LIPCAR A Mitochondrial lnc in the Noncoding RNA Chain

> Only one link of the chain of destiny can be handled at a time . > > — Winston Churchill All proteins are translated from RNA, but only a fraction of RNAs seem to be translated into proteins. Advanced genomics technologies have uncovered noncoding regulatory RNAs exhibiting extraordinary diversity in size, structure, and molecular function. We know a great deal about small (≈20 nucleotides) microRNAs that post-transcriptionally regulate translation of protein from target mRNAs having complementary 3′ sequences. These linear single-stranded nucleotides are transcribed either as independent gene products or as passengers within so-called miRtrons (microRNA-containing introns) of protein-coding genes and then processed and exported from the nucleus where they incorporate into RNA-induced silencing complexes.1 Because some microRNAs exhibit altered expression or differing circulating levels, they are being assessed as diagnostic biomarkers in cardiac disease. As yet, we know far less about the larger (>200 nucleotides) long noncoding RNAs (lncRNAs). lncRNAs are generated as antisense transcripts of protein-coding genes, as sense transcripts from within protein-coding gene introns, or as independent transcripts originating from intergenic regions.2 Unlike short microRNAs, lncRNAs are sufficiently long to develop multiple intramolecular RNA–RNA interactions conferring on them complex 3-dimensional structures. The unique physical configurations of different lncRNAs enable many of them to bind specific sets of proteins. Likewise, openly configured single-strand RNA sequences within lncRNA structures permit them to bind to complementary sequences in the genome. The combination of these 2 characteristics, protein binding and recognition of specific DNA sequences, evokes a characteristic lncRNA functionality: chaperoning transcriptional modulators or chromatin modifiers to specific genomic locations. In this manner, lncRNAs can epigenetically regulate gene expression.3 Article, see p 1569 Our nascent but growing understanding of lncRNA biology generally assumes that they are produced by, and act on, the nuclear genome. In this issue of Circulation Research …
Discussion of "The working alliance and the transference neurosis," by Ralph R. Greenson.

(2008). Discussion of “The Working Alliance and The Transference Neurosis,” by Ralph R. Greenson. The Psychoanalytic Quarterly: Vol. 77, No. 1, pp. 121-138.
In Honor of the Nobel Laureates Robert C. Merton and Myron S. Scholes: A Partial Differential Equation That Changed the World

The Nobel Prize was given to Robert C. Merton and Myron S. Scholes for discovering a new method for determining the value of an option. This is known as the Black-Merton-Scholes option pricing formula. The purpose of this essay is to explain why the Black-Merton-Scholes option pricing formula is so important to the finance profession, the economics profession, the financial industry, and society at large. This is done by studying the history of the formula's development, the economic logic underlying the formula's derivation, and the formula's ramifications for the various professions.
Embedded system to characterize HPA and calculate nonlinear predistortion neural network's weights for HPA

A major concern relating to the transmission of satellite has been the linearity of available high power amplifier (HPA). Travelling wave tube amplifier (TWTA) offer the greatest efficient and power capacity, but are some limited in linearity. The paper discuss the development a synthetic instrument with most advance DSP, FPGA and very fast DAC - A/D to generate, capture and calculation for BER, EVM as stated in L.H. Tran et al. (2003).The system can configurable to calculate nonlinear pre-distortion neural network's weights for RF power amplifier.
Office Based Photovaporization of the Prostate for Benign Prostatic Hyperplasia: Outcomes and Patient Satisfaction

Abstract Introduction We determined the efficacy, safety and tolerability of photovaporization of the prostate in the office setting for benign prostatic hyperplasia. Methods Between 2009 and 2011, 139 men with moderate to severe benign prostatic hyperplasia based on I-PSS (International Prostate Symptom Score) underwent photovaporization of the prostate using a 980 nm diode laser under local anesthesia. We compared preoperative and postoperative post-void residual urine volume, maximum urine flow and I-PSS/quality of life questionnaire responses. We also evaluated postoperative complications and patient satisfaction survey responses. Results An average ± SD of 782.5 ± 811.1 seconds of laser exposure at maximum power (180 W) resulted in a significant change in median post-void residual urine volume (–126 ml or –81.3%), maximum urine flow (4 ml per second or 40.0%) and I-PSS (–19 or –79.2%, each p Conclusions Office based photovaporization of the prostate can be a safe, effective and well tolerated approach to benign prostatic hyperplasia in office settings using local anesthesia. We believe that it can become an attractive low cost treatment option for the rapidly expanding population at risk for benign prostatic hyperplasia.
Reticulocytogenic Effects of Liver Extract and Congo Red in Guinea Pigs under Reduced Oxygen Tension

ConclusionsGuinea pigs subjected to reduced oxygen tensions showed prompt rises in reticulated red cells which reached a peak (8-14%), in 7-12 days. Then the reticulocytes decreased and in 3-4 weeks approached the control level.Intramuscular injection of liver extract prior to, simultaneously with, or following, exposure to reduced oxygen pressure, had no demonstrable effects on the reticulocyte response; and the bone marrow of liver-treated animals could not be distinguished from that of untreated controls.Congo red was also without effect on the reticullocyte response of guinea pigs under reduced oxygen tensions.
Potential of Adult Carabids (Coleoptera: Carabidae) as Predators of Fifth-Instar Codling Moth (Lepidoptera: Tortricidae) in Apple Orchards in California

This investigation compared the potential of adult carabids (ground beetles) as predators of fifth-instar codling moth, Cydia pomonella (L.). The three objectives of the research were the following: (1) to determine which species could kill C. pomonella , (2) to compare the degree of carnivory and consumption pattern of selected species of carabids, and (3) to estimate carabid predation of C. pomonella in the field. The results indicated that 75% or more of Pterostichus lustrans LeConte, Pterostichus cursitor LeConte, Pterostichus (Hypherpes) spp., Harpalus pensylvanicus DeGeer, or Anisodactylus californicus Dejean individuals were capable of killing C. pomonella in the laboratory. The most effective predators were species of Pterostichus , even when an alternative plant food (rolled oats) was provided. An average of 60% of tethered C. pomonella were consumed each night by carabids in early June, but predation intensity declined June–July. The carabid species seen attacking tethered prey included Agonum punctiforme Say, Calathus ruficollis Dejean, H. pensylvanicus , and P. (Hypherpes) spp. Adults of Pterostichus species appear to be important early-season predators of C. pomonella in orchards.
Production of pigments similar to those from hair from amino acid and keratin interaction.

SummaryThe soluble pigments produced when fat free nail keratin and tyrosine or tryptophan are boiled together with mineral acids differ from those produced when the keratin or amino acids are treated separately. The reaction involving tryptophan is enhanced by the simultaneous hydrolysis of keratin. Apparently keratin contributes some component (s) to the formation of pigment. The evidence favors the suggestion of Lee and Penrose that the red pigment obtained from human hair by the method of Arnow is not a natural pigment, but one produced from a colorless chromogen during the prolonged acid treatment. The pigment produced by the interaction of keratin and tryptophan in 6 N HO shows an absorption spectrum similar to that of the pigment trichosiderin, but contains no iron. The similarity of the absorption spectra suggests that the organic portion of the natural pigment may be derived in part from tryptophan.
Ruptured Pneumococcal Aortic Aneurysm Presenting as ST-Elevation Myocardial Infarction: Case Report and Literature Review

Ruptured mycotic aneurysms occur infrequently in current clinical practice, and a pneumococcal etiology is even more rare. This case report describes a patient who initially presented with catheter lab activation for an acute ST-elevation myocardial infarction, receiving a full Plavix load. She was subsequently found to have a ruptured aortic aneurysm and underwent emergency surgical repair, with intraoperative findings of an aorta seeded with Streptococcus pneumonia. A retrospective evaluation of her history revealed clues of a previous upper respiratory infection and long-standing back pain. The subsequent literature review summarizes presentations and outcomes in previously reported, ruptured pneumococcal aneurysms and describes the relatively common occurrence of aortic conditions masquerading as acute myocardial infarctions. We provide recommendations to help approach similar situations in the future.
Management of follicular and Hürthle cell neoplasms of the thyroid gland.

Management of follicular and Hurthle cell neoplasms of the thyroid gland is a common clinical problem. A diagnosis of follicular or Hurthle cell carcinoma cannot be made from a fine-needle aspiration biopsy alone because it requires histologic demonstration of capsular or vascular invasion. Thyroid lobectomy and isthmusectomy is adequate treatment of benign follicular or Hurthle cell adenoma and minimally invasive follicular carcinoma. Total thyroidectomy, radioiodine ablation, and thyrotropin-suppressive doses of thyroid hormone is advocated for the invasive subtype of follicular carcinoma and all Hurthle cell carcinomas. Monitoring of serum thyroglobulin levels postoperatively is important for detection of recurrent disease.
Maximum bandwidth snapshot channeled imaging polarimeter with polarization gratings

Compact snapshot imaging polarimeters have been demonstrated in literature to provide Stokes parameter estimations for spatially varying scenes using polarization gratings. However, the demonstrated system does not employ aggressive modulation frequencies to take full advantage of the bandwidth available to the focal plane array. A snapshot imaging Stokes polarimeter is described and demonstrated through results. The simulation studies the challenges of using a maximum bandwidth configuration for a snapshot polarization grating based polarimeter, such as the fringe contrast attenuation that results from higher modulation frequencies. Similar simulation results are generated and compared for a microgrid polarimeter. Microgrid polarimeters are instruments where pixelated polarizers are superimposed onto a focal plan array, and this is another type of spatially modulated polarimeter, and the most common design uses a 2x2 super pixel of polarizers which maximally uses the available bandwidth of the focal plane array.
Application of 1,3-Dipolar Cycloaddition in Azide Propellants

1,3-dipolar cycloaddition reaction was introduced.This reaction can be used in the modification of side chain of glycidyl azide polymer(GAP),cure of azides,and GAP propellant.It is shown that 1,3-dipolar cycloaddition is insensitive to water.Propellant based on this reaction can cure at 45-65℃.The problems of stability and compatibility between new curing age and high energy ingredient were solved,and low impact and firction sensitivity propellant could be obtained.As introduction of large group to the side chain,the mechanical property of this new propellant is relatively low.To improve this performance,modification crosslinking density and tacticity should be concerned.
Intimate partner violence, consenting to HIV testing and HIV status among Zambian women.

Sub-Saharan African countries are heavily burdened with HIV, which disproportionately affects women of reproductive age. Extant literature is inconsistent regarding the link between intimate partner violence and HIV. Data from the 2007 Zambian Demographic Health Survey of women aged 15–49 (n = 5014) were analysed. The influence of abuse by a current or former husband on consent to HIV testing and HIV positivity were evaluated. The unadjusted analysis showed a statistically significant association between intimate partner violence and consent to testing for HIV. Stratified analysis showed that there was a statistically significant association between intimate partner violence and HIV testing in rural areas but not in urban areas. However, the association lost its significance when adjusted for confounding factors. No statistically significant association was found between intimate partner violence and HIV-positive status. It is encouraging that women who experienced intimate partner were testing for HIV. P...
Accessing Siloxane Functionalized Polynorbornenes via Vinyl-Addition Polymerization for CO2 Separation Membranes

The vinyl addition polymerization of norbornyl-based monomers bearing polar functional groups is often problematic, leading to low molecular weight polymers in poor yield. Herein, we provide proof-of-principle evidence that addition-type homopolymers of siloxane substituted norbornyl-based monomers may be readily synthesized using the catalyst trans-[Ni(C6F5)2(SbPh3)2]. Polymerizations using this catalyst reached moderate to high conversion in just 5 min of polymerization and produced siloxane-substituted polymers with molecular weights exceeding 100 kg/mol. These polymers showed excellent thermal stability (Td ≥ 362 °C) and were cast into membranes that displayed high CO2 permeability and enhanced CO2/N2 selectivity as compared to related materials.
The Effect of Alcohol and Carbonyl Functional Groups on the Competition between Unimolecular Decomposition and Isomerization in C4 and C5 Alkoxy Radicals

Presented here are computed rates for the thermal unimolecular decomposition of a variety of alkoxy radicals with four- and five-carbon length backbones. Three classes of molecules are examined: alkoxy radicals with saturated hydrocarbon backbones, those with alcohol functional groups, and those with carbonyl functional groups. The chosen species represent many of those found during the combustion of fossil fuels as well as bio-derived alternatives. Density functional theory calculations were benchmarked against higher level coupled cluster calculations and used to explore the potential energy surfaces of these systems. Transition state theory was used to calculate high-pressure limit rate coefficients of all radical intermediates in the regimes relevant to atmospheric chemistry and combustion. We show that the assumption that alkoxy radicals quickly decompose via β-scission to aldehydes and other radicals is not valid for some of the alkoxy radicals investigated in this work. We further illustrate how intra-H migrations in larger alkoxy radicals with carbonyl and alcohol functional groups can dominate unimolecular decomposition under combustion and atmospheric relevant conditions. Finally, we discuss why carbonyl groups can increase or decrease intra-H migration barriers depending on their location relative to the transferring H-atom.