cssi/SciSciGPT-SciSciNet huggingface dataset:
Measuring Psychological Critical Thinking An Update

Critical thinking is widely considered an important skill for psychology majors. However, few measures exist of the types of critical thinking that are specific to psychology majors. Lawson (1999) designed the Psychological Critical Thinking Exam (PCTE) to measure students’ ability to “think critically, or evaluate claims, in a way that explicitly incorporates basic principles of psychological science” (p. 207). However, Lawson’s goal was not to present the PCTE as a standardized measure that was ready for use by other departments. We developed an updated version of the PCTE for broader use and investigated its reliability and validity. Results showed very good split-half and test–retest reliability. As expected, senior psychology majors scored significantly higher on the PCTE than junior psychology majors, senior biology majors, senior art majors, and introductory psychology students.
Using Mouse Genetics to Understand Infectious Disease Pathogenesis

The study of mouse and human genetic variation in infectious disease susceptibility (for review, see Malo and Skamene 1994; Hill 1998) should help to improve our knowledge of disease mechanisms by facilitating the identification of critical host proteins that modulate the infection process. Focusing on differences in disease susceptibility in humans will contribute to making progress in this field, but it is also possible to use mouse genetics to identify genes whose human orthologs are likely to affect the outcome of infections in man. It is impossible to adequately review all of the work that has been done to study the genetics of infectious disease susceptibility and pathogenesis. Therefore, I will discuss studies of two different bacterial infections. Although this is not a comprehensive approach, the examples help to illustrate my view that progress in understanding host susceptibility to infection will be facilitated by genetic studies of mouse models of infectious disease.
Management and Environment Effects on Dry Matter Yields of Three Brassica Species

Brassica crops have potential use as a forage during summer, fall, and early winter months. The influence of planting date and harvest date on the initial and regrowth herbage yields for three Brassica species: rape (B. napus L., 'Winfred' in 1987 and 'Emerald' in 1988 and 1989), turnip (B. rapa L., 'Purple Top'), and a turnip hybrid (B. rapa x B. pekinensis L., 'Tyfon') were investigated. The species were planted in late May to early June, late June to early July, and late July to early August in 1987, 1988, and 1989. Herbage yields before grazing were taken 64, 76, or 85 d after planting. The remaining herbage was allowed to regrow for 60, 70, or 80 d and then harvested [...]
Absorption and scattering of light by polydisperse aggregates

The absorption, scattering, and differential scattering cross sections are presented for polydisperse aggregates of prescribed fractal dimension and uniform primary particle size. These optical properties are formulated for polydisperse aggregates in terms of the primary particle diameter, the appropriate moments of the discrete size distribution function, and the mean-square radius of gyration. The absorption and scattering cross sections are compared with Rayleigh theory in the small size limit and with the results of the computational simulations of Mountain and Mulholland [ Langmuir4, 1321 ( 1988)] for intermediate and large aggregates. The differential scattering cross sections are well correlated by the law of Guinier together with a power-law expression for the larger sizes. The cross sections that are described herein apply in particular to polydisperse fractallike aggregates that are formed by cluster–cluster aggregation and possess a size scale that is pertinent to laboratory experiments and industrial processes.
H 2 -optimization with stable controllers

Abstract In this paper, the problem of designing a H 2 -optimal stable feedback controller for a linear time-invariant system is considered. An algorithm is presented for obtaining such a stable controller. The degradation in the system performance is minimized while maintaining the closed-loop internal stability. For scalar systems, this is achieved by minimizing a non-linear objective function of a parameter vector subject to non-linear inequality constraints.
Tree and impervious cover change in U.S. cities

City trees Ecosystem services Forest monitoring Urban forestry Urban greening Urban trees a b s t r a c t Paired aerial photographs were interpreted to assess recent changes in tree, impervious and other cover types in 20 U.S. cities as well as urban land within the conterminous United States. National results indicate that tree cover in urban areas of the United States is on the decline at a rate of about 7900 ha/yr or 4.0 million trees per year. Tree cover in 17 of the 20 analyzed cities had statistically significant declines in tree cover, while 16 cities had statistically significant increases in impervious cover. Only one city (Syracuse, NY) had a statistically significant increase in tree cover. City tree cover was reduced, on average, by about 0.27 percent/yr, while impervious surfaces increased at an average rate of about 0.31 percent/yr. As tree cover provides a simple means to assess the magnitude of the overall urban forest resource, monitoring of tree cover changes is important to understand how tree cover and various environmental benefits derived from the trees may be changing. Photo-interpretation of digital aerial images can provide a simple and timely means to assess urban tree cover change to help cities monitor progress in sustaining desired urban tree cover levels. Published by Elsevier GmbH.
A literature review: robots in medicine

Robotic systems employed in the laboratory, in rehabilitation, and in surgery are reviewed. The advantages of using a robot system over manual procedures in the laboratory to prepare samples is discussed, and some of the obstacles are noted. A typical laboratory robot is described. Rehabilitative applications in the major research areas of tactile sensors, assistive devices for the blind, prosthetics, and orthotics are examined. Manipulators that can help a disabled individual with important everyday tasks and other assistive robotic systems in rehabilitation are described. A variety of robots that assist or perform surgery is surveyed. These applications include positioning in stereotactic neurosurgery, patient manipulation, an in vivo spinal kinematic instrument, and robotic radial keratotomy, among others. >
N-Acetylcysteine Amide (NACA) Prevents Retinal Degeneration by Up-Regulating Reduced Glutathione Production and Reversing Lipid Peroxidation

Oxidative stress plays a critical role in accelerating retinal pigment epithelial dysfunction and death in degenerative retinal diseases, including age-related macular degeneration. Given the key role of oxidative stress–induced retinal pigment epithelial cell death and secondary photoreceptor loss in the pathogenesis of age-related macular degeneration, we hypothesized that a novel thiol antioxidant, N-acetylcysteine amide (NACA), might ameliorate cellular damage and subsequent loss of vision. Treatment of human retinal pigment epithelial cells with NACA protected against oxidative stress–induced cellular injury and death. NACA acted mechanistically by scavenging existing reactive oxygen species while halting production of reactive oxygen species by reversing lipid peroxidation. Furthermore, NACA functioned by increasing the levels of reduced glutathione and the phase II detoxification enzyme glutathione peroxidase. Treatment of mice exposed to phototoxic doses of light with NACA maintained retinal pigment epithelial cell integrity and prevented outer nuclear layer cell death as examined by histopathologic methods and rescued photoreceptor function as measured by electroretinography. These observations indicate that NACA protects against oxidative stress–induced retinal pigment epithelial and photoreceptor cell death in vitro and in vivo. The data suggest that NACA may be a novel treatment in rescuing retinal function and preventing vision loss secondary to retinal degenerative diseases, including age-related macular degeneration.
Speech Codes Theory

Speech codes theory is an account of communication as a deeply cultured human activity. The theory, and the empirical research on which it is built, demonstrate that the kinds of local knowledge people deploy to talk about—to characterize, interpret, and rationalize—their communicative conduct is indeed local, particular knowledge, and that such knowledge can be discovered and described through systematic inquiry. This article describes the key theoretical commitments of speech codes theory, identifies its six propositions, illustrates research within the tradition, and assesses its purposes. Keywords: applied communication; communication research methods; communication theory; group communication; intercultural communication
Minimally Invasive Management of Complicated Diverticular Disease: Current Status and Review of Literature

Diverticulitis is a common condition which carries significant morbidity and socioeconomic burden (McGillicuddy et al in Arch Surg 144:1157–1162, 2009). The surgical management of diverticulitis has undergone significant changes in recent years. This article reviews the role of minimally invasive approach in management of complicated diverticulitis, with a focus on recent concepts and advances. A literature review of past 10 years (January 2004 to September 2014) was performed using the electronic database MEDLINE from PubMed which included articles only in English. We identified total of 139 articles, out of which 50 were excluded resulting in 89 full-text articles for review 16 retrospective studies, 7 prospective cohorts, 1 case–control series and 1 systematic review were included. These suggest that urgent surgery is performed for those with sepsis and diffuse peritonitis or those who fail to improve despite medical therapy and/or percutaneous drainage. In addition, 3 randomized control trials: DILALA, LapLAND and the Scandinavian Diverticulitis trial are working towards evaluating whether laparoscopic lavage is safe in management of complicated diverticular diseases. Growing trend toward conservative or minimally invasive treatment modality even in severe acute diverticulitis was noticed. Laparoscopic peritoneal lavage has evolved as a good alternative to invasive surgery, yet clear indications for its role in the management of complicated diverticulitis need to be established. Recent evidence suggests that existing guidelines for optimal management of complicated diverticulitis should be updated. Non-resectional radiographic techniques are likely to play a prominent role in the initial treatment of complicated diverticulitis in the near future.
Electromyographic investigation of the relationship of the effects of selected parameters on concurrent study of voice and oboe

Summary Given the great diversity of opinion among teachers regarding the advisability of simultaneous study of both voice and an instrument, this study was conducted to determine whether specific scientific measurements would indicate deleterious effects on the voice or would indicate no such detriment on concurrent study of voice and oboe. Electromyographic analyses were made of the abdominal and the suprahyoid areas. Conclusions were that changes in quality may result from the tight lip embouchure, closed jaw position, and elevation of the larynx used in oboe playing. Although pedagogues are divided regarding methods of breathing, all agree there must be control. This study indicated definite changes in muscle activity, both abdominal and suprahyoid, during concurrent study.
Fracture Healing Properties of Asphaltic Material under Controlled Damage

The self-healing properties of asphalt materials present a new means to achieve reliable, durable, and sustainable asphalt pavements through maximizing the effect of microdamage recovery. However, healing (healing of fracture damage) normally happens in conjunction with the recovery of viscoelastic deformation, making the analysis of healing complicated. This paper conducts a comprehensive evaluation of the fracture healing properties of asphalt binder under different damage levels while excluding the effect of viscoelastic recovery. It develops a simple healing testing protocol and a data analysis method that can create fracture damage in the material, assess the level of damage before rest periods, monitor the change of material properties during the healing process, and evaluate the effect of fracture healing on material performance. Healing functions are developed to model the healing characteristics of asphalt binder during the rest under different damage levels and temperatures. Based on the testing results for two binders (PG64-28 and PG70-28), it is found that fracture healing dominates the long-term modulus recovery, while the viscoelasticity contributes greatly for early modulus gain right after the load is removed. The fracture healing properties and the recovery of fatigue performance are strongly affected by temperature and the damage level prior to rest.
Immunosuppression in Atherosclerosis Mobilizing the Opposition Within

An estimated 1014 microbes live on our mucosal surfaces, exceeding by far the number of cells in our body (approximately 1013). Survival depends on our ability to recognize, wall off, and eliminate unwanted intruders. The doubling of life expectancy over the last century has created an internal burden of degenerating tissue, cellular debris, and malignant transformation, adding considerable stress to host defense mechanisms. The most powerful protective tool that we have is inflammation, a generic response pattern that allows the immune system to rapidly recognize threats, mobilize cells to injury sites, remove instigators, and heal wounds. Articles pp 1968 and 1977 Acute inflammation is short-lived and characterized by the recruitment of polymorphonuclear granulocytes followed by monocytes. Inflammation is self-amplifying and intensified through the sequential release of lipid mediators, cytokines, and chemokines. By 48 to 72 hours, granulocytes are replaced by lymphocytes. Despite the domino effect of a few inflammatory cells recruiting millions of others, inflammation is usually self-limited, resolving within days to weeks. If not, the response switches to chronic mode. Lymphocytes then dominate the force of inflammatory cells, and new rules dictate cell-cell communication, collateral damage, and repair. Most diseases categorized as chronic inflammatory disorders persist over decades, bringing a much greater time dimension to the inflammatory process. Although atherosclerosis is a quintessential chronic, persistent inflammatory disease,1 it differs from most others because its smoldering disease activity lasts for 30 to 70 years. Obviously, the mechanisms of acute and chronic inflammation are distinct; granulocytes and lymphocytes utilize fundamentally different means to recognize danger and react. Neutrophils, which live only for hours and generate no memory of their engagement with harmful substances, sense microbial and nonmicrobial danger signals through inherited receptors that are similar in all hosts. Lymphocytes, however, are long-lived cells; some survive for decades and …
Whispering Gallery Mode Lasing from Zinc Oxide Hexagonal Nanodisks

Disk-shaped semiconductor nanostructures provide enhanced architectures for low-threshold whispering gallery mode (WGM) lasing with the potential for on-chip nanophotonic integration. Unlike cavities that lase via Fabry-Perot modes, WGM structures utilize low-loss, total internal reflection of the optical mode along the circumference of the structure, which effectively reduces the volume of gain material required for lasing. As a result, circularly resonant cavities provide much higher quality (Q) factors than lower reflection linear cavities, which makes nanodisks an ideal platform to investigate lasing nanostructures smaller than the free-space wavelength of light (i.e., subwavelength laser). Here we report the bottom-up synthesis and single-mode lasing properties of individual ZnO disks with diameters from 280 to 900 nm and show finite difference time domain (FDTD) simulations of the whispering gallery mode inside subwavelength diameter disks. These results demonstrate ultraviolet WGM lasing in chemically synthesized, isolated nanostructures with subwavelength diameters.
Determining the Vapor Pressures of Diacetone Diperoxide (DADP) and Hexamethylene Triperoxide Diamine (HMTD)

The vapor signature of diacetone diperoxide (DADP) and hexamethylene triperoxide diamine (HMTD) were examined by a gas chromatography (GC) headspace technique over the range of 15 to 55 °C. Parallel experiments were conducted to redetermine the vapor pressures of 2,4,6-trinitrotoluene (TNT) and triacetone triperoxide (TATP). The TNT and TATP vapor pressures were in agreement with the previously reported results. Vapor pressure of DADP was determined to be 17.7 Pa at 25 °C, which is approximately 2.6 times higher than TATP at the same temperature. The Clapeyron equation, relating vapor pressure and temperature, was LnP (Pa)=35.9−9845.1/T (K) for DADP. Heat of sublimation, calculated from the slope of the line for the Clapeyron equation, was 81.9 kJ mole−1. HMTD vapor pressure was not determined due to reduced thermal stability resulting in vapor phase decomposition products.
In-situ Observation of Silicon Epitaxy Breakdown with Real-Time Spectroscopic Ellipsometry

We use in-situ real-time spectroscopic ellipsometry to observe the breakdown of silicon epitaxy during growth by hot-wire chemical vapor deposition (HWCVD) on Si (100) substrates. Representative data is presented for the two types of epitaxy breakdown that we have observed: 1) an immediate transition to hydrogenated amorphous silicon (a-Si:H), and 2) a slower transition where a-Si:H cones nucleate and grow until they eclipse further epitaxial growth. Simple models, consistent with transmission-electron and atomic-force micrographs, describe the evolution of both types of breakdown showing that real-time spectroscopic ellipsometry is a useful tool for monitoring the growth of epitaxial silicon.
The energy trade-offs of adapting to a water-scarce future: case study of Los Angeles

AbstractIncreasing water competition, population growth and global climate change will intensify the tension between water and energy resources in arid climates of the world, since energy costs underscore the challenges facing water security in dry regions. In few places is the tension between water and energy resources more pronounced than in Los Angeles, California. This article analyzes the city’s current water supply and estimates its future energy requirements based on water supply projections from the Los Angeles Department of Water and Power. Results suggest that while increasing local water management strategies could reduce the future energy intensity of the water supply, an increased reliance on water transfers could worsen its future energy intensity.
The adoption of mark-up tools in an interactive e-textbook reader

Researchers have more often examined whether students prefer using an e-textbook over a paper textbook or whether e-textbooks provide a better resource for learning than paper textbooks, but students’ adoption of mark-up tools has remained relatively unexamined. Drawing on the concept of Innovation Diffusion Theory, we used educational data mining techniques and survival analysis to examine time to adoption of highlights, notes, annotations, bookmarks, and questions in an interactive e-textbook reader. We found that the only tool that more than half of the participants used was highlighting. Students who purchased a printed copy of the textbook had longer average times to using notes and annotations. Because most of the more interactive tools were used by a relatively small number of students, regression modeling of the factors associated with tool usage was difficult. However, there was evidence that the likelihood of using the tools decreased as the semester progressed, and that students’ self-reported reading behaviors and grade point average were predictive of the time to using the mark-up tools. An interaction between bookmark usage and amount of reading was positively associated with course grades, suggesting that a strategy of bookmarking with frequent reading could assist students to learn content successfully. The implications of this research are that (1) instructors may need to more directly scaffold the adoption of interactive e-textbook tools that are touted as boosts to student learning and (2) promoting adoption early, shortly after students begin reading the e-textbook, is critical for students to acclimate to using the tool.
Videos in clinical medicine. Technique for temporary pelvic stabilization after trauma.

Early temporary pelvic stabilization can reduce hemorrhage from pelvic-ring fractures. This video demonstrates the use of pelvic sheeting to provide mechanical stabilization of pelvic-ring fracture.
The HO-1/CO system regulates mitochondrial-capillary density relationships in human skeletal muscle.

The heme oxygenase-1 (HO-1)/carbon monoxide (CO) system induces mitochondrial biogenesis, but its biological impact in human skeletal muscle is uncertain. The enzyme system generates CO, which stimulates mitochondrial proliferation in normal muscle. Here we examined whether CO breathing can be used to produce a coordinated metabolic and vascular response in human skeletal muscle. In 19 healthy subjects, we performed vastus lateralis muscle biopsies and tested one-legged maximal O2 uptake (Vo2max) before and after breathing air or CO (200 ppm) for 1 h daily for 5 days. In response to CO, there was robust HO-1 induction along with increased mRNA levels for nuclear-encoded mitochondrial transcription factor A (Tfam), cytochrome c, cytochrome oxidase subunit IV (COX IV), and mitochondrial-encoded COX I and NADH dehydrogenase subunit 1 (NDI). CO breathing did not increase Vo2max (1.96 ± 0.51 pre-CO, 1.87 ± 0.50 post-CO l/min; P = not significant) but did increase muscle citrate synthase, mitochondrial density (139.0 ± 34.9 pre-CO, 219.0 ± 36.2 post-CO; no. of mitochondrial profiles/field), myoglobin content and glucose transporter (GLUT4) protein level and led to GLUT4 localization to the myocyte membrane, all consistent with expansion of the tissue O2 transport system. These responses were attended by increased cluster of differentiation 31 (CD31)-positive muscle capillaries (1.78 ± 0.16 pre-CO, 2.37 ± 0.59 post-CO; capillaries/muscle fiber), implying the enrichment of microvascular O2 reserve. The findings support that induction of the HO-1/CO system by CO not only improves muscle mitochondrial density, but regulates myoglobin content, GLUT4 localization, and capillarity in accordance with current concepts of skeletal muscle plasticity.
The Computed Tomography Quadrate Lobe "Hot Spot" Sign.

CASE DESCRIPTION A41-year-old Hispanic female presented with 1-week history of exertional dyspnea, and abdominal pain with distention. Other medical problems included end-stage renal disease on intermittent hemodialysis, congestive heart failure and history of catheter-associated superior vena cava (SVC) thrombosis. Physical examination revealed decreased breath sounds over lung bases, abdominal distention with shifting dullness and pedal edema. Examination of the skin, face and arms were unremarkable. Computed tomogram (CT) scan of the abdomen with contrast (Figure) showed ascites and a 4.5 cm intense arterial-enhancing focus in the quadrate lobe of the liver (arrows). The patient’s symptoms improved after emergent hemodialysis and was discharged thereafter. This imaging finding was consistent with the CT quadrate lobe “hot spot” sign demonstrating cavoportal collaterals, which in our patient appeared after the development of SVC thrombosis. However, it persisted even after documented resolution of the SVC thrombus, likely from slow regression of the dilated collaterals. Historically described in Technetium99m scan, the liver “hot spot” is a focal increased uptake of
Phosphoinositide binding inhibits actin crosslinking and polymerization by palladin

Actin cytoskeleton remodeling requires the coordinated action of a large number of actin binding proteins that reorganize the actin cytoskeleton by promoting polymerization, stabilizing filaments, causing branching, or crosslinking filaments. Palladin is a key cytoskeletal actin binding protein whose normal function is to enable cell motility during development of tissues and organs of the embryo and in wound healing, but palladin is also responsible for regulating the ability of cancer cells to become invasive and metastatic. The membrane phosphoinositide phosphatidylinositol (PI) 4,5-bisphosphate [PI(4,5)P2] is a well-known precursor for intracellular signaling and a bona fide regulator of actin cytoskeleton reorganization. Our results show that two palladin domains [immunoglobulin (Ig) 3 and 34] interact with the head group of PI(4,5)P2 with moderate affinity (apparent Kd=17μM). Interactions with PI(4,5)P2 decrease the actin polymerizing activity of Ig domain 3 of palladin (Palld-Ig3). Furthermore, NMR titration and docking studies show that residues K38 and K51, which are present on the β-sheet C and D, form salt bridges with the head group of PI(4,5)P2. Moreover, charge neutralization at lysine 38 in the Palld-Ig3 domain severely limits the actin polymerizing and bundling activity of Palld-Ig3. Our results provide biochemical proof that PI(4,5)P2 functions as a moderator of palladin activity and have also identified residues directly involved in the crosslinking activity of palladin.
Blind Imitation: The Revolting Persistence of Bowers V. Hardwick

In Bowers v. Hardwick, the U.S. Supreme Court upheld the criminal prohibition of sodomy. In dissent to that landmark decision, Justice Harry Blackmun, quoting Justice Oliver Wendell Holmes, denounced as “revolting” any rule of law that “simply persists from blind imitation of the past.” Bowers was explicitly overruled in 2003 by Lawrence v. Texas. But by that time, most federal Circuit Courts had applied the reasoning of Bowers to reject any suggestion that sexual orientation might be a suspect classification under the Fourteenth Amendment. As it turns out, the overrule of Bowers by Lawrence did little to disrupt the blind imitation of bad precedent by the lower courts, which still persists today.This article illustrates how federal appellate courts have applied the reasoning of Bowers to foreclose any consideration whether sexual orientation can constitute a suspect class, and have applied rational basis scrutiny to state actions targeting gays and lesbians. This article shows how Bowers’ reasoning has been upheld repeatedly, long after the case was overruled, despite an attempted insurrection by district court judges in the wake of United States v. Windsor. Finally, the article describes how Obergefell v. Hodges has failed to disrupt Bowers-based precedent and what courts still must do, thirty years later, to put to rest a revolting decision that was “wrong when it was decided.”
Icsbp/Irf8 Cooperates with Tel to Regulate Fas Induced Apoptosis in Myeloid Leukemia.

Abstract 395 The interferon consensus sequence binding protein (Icsbp) is an interferon regulatory transcription factor (also known as Irf8) which functions as an anti-oncogene for chronic myeloid leukemia (CML) and acute myeloid leukemia (AML). In previous studies we used chromatin immunoprecipitation based high through put screening approaches to identify Icsbp target genes which explain these effects. The identified set of target genes was enriched for genes encoding proteins which regulate cytokine induced proliferation, beta catenin activity, and Fas induced apoptosis. In further investigations of the latter category, we found that Icsbp represses transcription of PTPN13 ; the gene encoding Fas associated phosphatase 1 (Fap1). Fap1 binds directly to the C-terminus of Fas, resulting in Fas-dephosphorylation and antagonizing Fas-induced apoptosis. We found that repression of PTPN13 by Icsbp increased during myelopoiesis, resulting in decreased Fap1 expression and increased sensitivity to Fas-induced apoptosis as differentiation proceeds. In the current studies, we investigated the mechanism for Icsbp induced PTPN13 repression. We identified a multi-protein repression complex which includes Icsbp, the ets protein Tel, and Hdac3 which binds to a PTPN13 cis element in a manner requiring recognition of the binding site by Tel. We found that histone deacetylase activity of Hdac3 was essential for PTPN13 repression by this complex. Tel was first identified due to participation in a leukemia associated chromosomal translocation with the gene encoding the PdgfRβ. This translocation is characteristic of Chronic Myelomonocytic Leukemia (CMMoL) and results in expression of a fusion protein with the protein-protein interaction domain of Tel and the kinase domain of PdgfRβ. Tel/PdgfRβ fusion protein exhibits constitutive tyrosine kinase activity due to autophosphorylation and activation of fusion protein dimers. This results in transduction of proliferative signals in the absence of cytokine. In this work we identify another function for the Tel/PdgfRβ fusion protein which may also contribute to the pathogenesis of leukemia. We find that Tel/PdgfRβ fusion protein interacts with wild type Tel protein in the cell (expressed by the allele not involved in the translocation), consistent with results of previous investigators. More importantly, we find that interaction with Tel/PdgfRβ renders Tel unavailable for binding to the PTPN13 cis element, which prevents assembly of the Tel/Icsbp/Hdac3 repression complex. The net result is increased PTPN13 promoter activity and Fap1 expression in cells expressing Tel/PdgfRβ fusion protein. This increase in Fap1 expression contributes to resistance to Fas-induced apoptosis in these cells. Therefore, our studies identify a previously unrecognized mechanism for apoptosis resistance in CMMoL and a potential target for therapeutic intervention in this myelodysplastic/ myeloproliferative disorder. Disclosures: No relevant conflicts of interest to declare.
Data Flow Requirements for Integrating Smart Buildings and a Smart Grid through Model Predictive Control

Abstract A truly energy efficient and sustainable society requires intelligence embedded at all levels within energy production and consumption systems. The ‘smartness’ of a smart grid is wasted if major consumption locations, ranging from individual buildings to larger collection of buildings (such as campuses or cities) don’t have a comparable level of intelligence. Model predictive control (MPC) is an effective tool for integrating the smart grid with future smart buildings. Interest is growing about the need to research the application of MPC to the operation of building systems; however, full-scale MPC concepts have not made it yet into commercially available building energy management systems. Much of the prior published work uses a simplified description of building and systems performance in order to reduce computational complexity. We describe in this paper a vision for data flow and modeling developments that a future, high level control system will need. This would allow a smart building or connected campus of buildings to effectively integrate an overall operational strategy for a future time horizon of 24-48 hours to minimize the energy consumption and cost, enable integration of regional renewable energy sources, and, importantly, consider human factors such as building indoor environmental quality (thermal comfort indoor air quality, etc.). This idealized data exchange and systems control network would obtain or predict data on parameters such as the real-time cost of electricity, renewable energy production, building cooling and heating loads, and current system disruptions (such as equipment maintenance). System monitoring would provide feedback for advanced features such as adaptive learning and automated fault detection and diagnostics. In addition to the idealized future system that is fully capable as described, we discuss some of the issues involved with trying to implement these concepts in older, existing building systems.
Totaliter Aliter, God’s Mission, and the Postcolonial

God’s mission theology finds a critical import in the postcolonial context of World Christianity, which has emerged as both a challenge and an opportunity for Western theology and its missional practices. God’s mission, re-imagined in this expansive global framework, functions as indigenous translations embedded within an emancipatory horizon in the aftermath of colonialism. Given this, I find it substantial to explicate the life horizon of God’s mission, hermeneutically relating its interconnection with other theological foci. Given this, I shall reread Karl Barth in light of theological phenomenology of totaliter aliter with respect to postcolonial theory. A phenomenology of God’s mission in speech-act seeks to develop its religious discourse in multiple senses, taking issue with the natural attitude or understanding of it (the first naivete). A phenomenological approach to God’s mission is of a postcolonial character to undergird enculturation, emancipation, and comparative study of religion for a deeper meaning of God’s activity in the world of religions. Comparative epistemology in faith seeking understanding is renewed and deepened in the postcolonial discussion of faith and the Other.
Thioridazine (MellarilR) Ocular Toxicity

Thioridazine retinopathy has been well documented in patients receiving in excess of the recommended maximal daily dosage of 800 mg (Siddall, 1968). Clinical signs and symptoms of toxicity include decreased visual acuity, visual field defects and retinal pigment epithelial disturbances. Marked suppression of the ERG and diminished reactivity of the EOG are characteristic of advanced toxicity with this drug. The pathogenesis of this disorder is thought to be selective uptake of thioridazine in pigmented uveal tissue and the retinal pigment epithelium with resultant local toxicity. The present report concerns a schizophrenic patient who developed ocular symptoms of thioridazine toxicity after self-regulating her medication dose. After thioridazine was discontinued, visual acuity returned to normal, but even six months following cessation of the medication the ERG and EOG were still abnormal.
“Deformable Wheel”-A Self-recovering Modular Rolling Track

The rolling track is an effective modular robot configuration with high maneuverability. However, one technical barrier that prevents it from practical usage is that most existing rolling track robots must start from a typical stand-up position and they are also difficult to turn while rolling. This paper presents a solution for these problems. By extending our previous work, we have developed a set of new gaits for the rolling track to self-standup, roll and turn. The combination of these behaviors on a single SuperBot rolling track has enabled it to roll from any initial conditions, steer while rolling, and recover from falling sideways. These new gaits have been demonstrated with 6 modules in hardware and 8 and 10 modules in simulation. In addition, the new gaits can be activated even reconfiguring from a snake configuration.
Generalized Stability Analysis of a Non-Linear Dynamic Model

In the study of dynamic systems, modellers have usually enquired after the existence, uniqueness, and stability of equilibrium solutions (Casti 1985). Unless a systems model hails from a non-equilibrium tradition, establishing the existence of an equilibrium solution (usually long-term) has been deemed important for finding states in which system components are in some sense well-aligned, but also for ensuring that the model is properly constructed and ‘closed’ from a theoretical perspective. Determining whether or not an equilibrium solution is unique has been considered important for delimiting the scope of solution space that needs to be investigated to understand system behaviour. In non-linear systems, however, unique solutions are unlikely. Moreover, there may be good theoretical reasons for why one should expect to observe multiple equilibria in some complex systems (see Farmer 1993). The stability of a solution and the nature of this stability are analysed to determine whether the solution represents a state the system will persist in or diverge from if shocked and whether it is a state to which all or only some paths will converge. Stability analysis also concerns whether a model is structurally stable over some relevant range of parameter values such as the confidence intervals of the parameter estimates (Wymer 1987; Gandolfo 1992).
CHEMICAL PROPERTIES OF THE Si-H BOND

The reactions of di- and trichlorosilane with a variety of organic substrates are contrasted. The chemistry of these materials in the presence of tert -amines is discussed as well as their mode of addition to olefins and acetylenes under various catalylic conditions. Anomalies associated with the relative rates of addition of these two chlorosilanes to olefins are disclosed.
Principal Component Analysis on non-Gaussian Dependent Data

In this paper, we analyze the performance of a semiparametric principal component analysis named Copula Component Analysis (COCA) (Han & Liu, 2012) when the data are dependent. The semiparametric model assumes that, after unspecified marginally monotone transformations, the distributions are multivariate Gaussian. We study the scenario where the observations are drawn from non-i.i.d. processes (m-dependency or a more general ϕ-mixing case). We show that COCA can allow weak dependence. In particular, we provide the generalization bounds of convergence for both support recovery and parameter estimation of COCA for the dependent data. We provide explicit sufficient conditions on the degree of dependence, under which the parametric rate can be maintained. To our knowledge, this is the first work analyzing the theoretical performance of PCA for the dependent data in high dimensional settings. Our results strictly generalize the analysis in Han & Liu (2012) and the techniques we used have the separate interest for analyzing a variety of other multivariate statistical methods.
Meteorological effects on long-range nonlinear propagation of jet noise from a static, high-performance military aircraft

The impact of nonlinearity on the propagation of noise from military jet aircraft has been fairly well documented, but only within a few hundred meters from the aircraft. This paper describes analysis of nonlinear propagation for morning static runups of F-35 aircraft at greater distances, out to 1220 m near the direction of maximum radiation and at heights ranging from 0 m up to 30.5 m. A comparison of overall levels with distance and height reveals evidence of significant atmospheric refraction effects, and a general trend of decreasing level with height. Examination of nonlinearity metrics reveals opposite behavior, however. At these distances, nonlinear propagation effects are often strongest in waveforms with lower sound levels, which is counterintuitive. One important finding, however, is that acoustic shock strength can vary greatly from runup to runup, even for seemingly small changes in atmospheric conditions. This analysis demonstrates the need for further research into long-range nonlinear propagation of jet noise through realistic atmospheric conditions.The impact of nonlinearity on the propagation of noise from military jet aircraft has been fairly well documented, but only within a few hundred meters from the aircraft. This paper describes analysis of nonlinear propagation for morning static runups of F-35 aircraft at greater distances, out to 1220 m near the direction of maximum radiation and at heights ranging from 0 m up to 30.5 m. A comparison of overall levels with distance and height reveals evidence of significant atmospheric refraction effects, and a general trend of decreasing level with height. Examination of nonlinearity metrics reveals opposite behavior, however. At these distances, nonlinear propagation effects are often strongest in waveforms with lower sound levels, which is counterintuitive. One important finding, however, is that acoustic shock strength can vary greatly from runup to runup, even for seemingly small changes in atmospheric conditions. This analysis demonstrates the need for further research into long-range nonlinear prop...
Interaction or Segregation: Vaccination and Information Sharing on Twitter

It is argued that anti-vaccination advocates use social media to spread their influence. At the same time pro-vaccination groups are having a stronger social-media presence. This study examined information-sharing behavior regarding vaccination by analyzing hyperlinks shared on Twitter, and found that these two groups exhibit different behaviors. While anti-vaccination group uses embedded URLs more than the pro-vaccination one, they pool from the smaller group of URLs risking the echo chamber or filter bubble effects. Unsurprisingly, there are very few information sources shared by both groups.
Root endophytes and invasiveness: no difference between native and non‐native Phragmites in the Great Lakes Region

Microbial interactions could play an important role in plant invasions. If invasive plants associate with relatively more mutualists or fewer pathogens than their native counterparts, then microbial communities could foster plant invasiveness. Studies examining the effects of microbes on invasive plants commonly focus on a single microbial group (e.g., bacteria) or measure only plant response to microbes, not documenting the specific taxa associating with invaders. We surveyed root microbial communities associated with co‐occurring native and non‐native lineages of Phragmites australis, across Michigan, USA. Our aim was to determine whether (1) plant lineage was a stronger predictor of root microbial community composition than environmental variables and (2) the non‐native lineage associated with more mutualistic and/or fewer pathogenic microbes than the native lineage. We used microscopy and culture‐independent molecular methods to examine fungal colonization rate and community composition in three major microbial groups (bacteria, fungi, and oomycetes) within roots. We also used microbial functional databases to assess putative functions of the observed microbial taxa. While fungal colonization of roots was significantly higher in non‐native Phragmites than the native lineage, we found no differences in root microbial community composition or potential function between the two Phragmites lineages. Community composition did differ significantly by site, with soil saturation playing a significant role in structuring communities in all three microbial groups. The relative abundance of some specific bacterial taxa did differ between Phragmites lineages at the phylum and genus level (e.g., Proteobacteria, Firmicutes). Purported function of root fungi and respiratory mode of root bacteria also did not differ between native and non‐native Phragmites. We found no evidence that native and non‐native Phragmites harbored distinct root microbial communities; nor did those communities differ functionally. Therefore, if the trends revealed at our sites are widespread, it is unlikely that total root microbial communities are driving invasion by non‐native Phragmites plants.
A weak Fano threefold arising as a blowup of a curve of genus 5 and degree 8 on $${\mathbb {P}}^3$$ P 3

This article constructs a smooth weak Fano threefold of Picard number two with small anticanonical morphism that arises as a blowup of a smooth curve of genus 5 and degree 8 in \({\mathbb {P}}^3\). While the existence of this weak Fano was known as a numerical possibility in Cutrone and Marshburn (Cent Eur J Math 11(9):1552–1576, 2013) and constructed in Blanc and Lamy (Proc Lond Math Soc 105(5):1047–1075, 2012), this paper removes the dependencies on the results in Jahnke et al. (Cent Eur J Math 9(3):449–488, 2011) needed in the construction of Blanc and Lamy (Proc Lond Math Soc 105(5):1047–1075, 2012) and constructs the link in the style of Arap et al. (Math Scand 120(1):68–86, 2017).
Division algebras and supersymmetry II

Author(s): Baez, JC; Huerta, J | Abstract: Starting from the four normed division algebras - the real numbers, complex numbers, quaternions and octonions - a systematic procedure gives a 3-cocycle on the Poincare Lie superalgebra in dimensions 3, 4, 6 and 10. A related procedure gives a 4-cocycle on the Poincare Lie superalgebra in dimensions 4, 5, 7 and 11. In general, an (n + 1)-cocycle on a Lie superalgebra yields a "Lie n-superalgebra": that is, roughly speaking, an n-term chain complex equipped with a bracket satisfying the axioms of a Lie superalgebra up to chain homotopy. We thus obtain Lie 2-superalgebras extending the Poincare superalgebra in dimensions 3, 4, 6 and 10, and Lie 3-superalgebras extending the Poincare superalgebra in dimensions 4, 5, 7 and 11. As shown in Sati, Schreiber and Stasheff's work on higher gauge theory, Lie 2-superalgebra connections describe the parallel transport of strings, while Lie 3-superalgebra connections describe the parallel transport of 2-branes. Moreover, in the octonionic case, these connections concisely summarize the fields appearing in 10- and 11-dimensional supergravity. © 2011 International Press.
Building Collaboratives with Southern Rural African American Churches through the Integration of the Interorganizational Collaborative Framework

The rural Black church often plays an important role in the lives of many African Americans and frequently functions as an informal helping network in meeting emergency service needs for this group. This article provides a review of the constructs of the Bailey and McNalley-Koney Interorganizational Community-Based Collaborative Framework. Additionally, this paper explores action-oriented measures for integrating constructs into practice to build interorganizational collaboratives with southern rural African American churches.
Coming to Terms with Term States

In multielectron atoms or molecules, quantized electronic energy states known as term states provide a framework for interpreting absorption and emission spectra. Enumerating the term states associ...
The sign of contradiction: Church defense and the liturgical gun:

In recent years, high-profile church shootings have captured the attention and the moral imaginations of US Christians. The reasons for the shootings are multitude, but in practice the response amo...
Implicit arguments in English double object constructions

Pesetsky (1995) argued that both objects in the double object construction must be selected arguments of the lexical verb, based on patterns of optionality. A closer examination shows that this is not correct. The second object of the double object construction and both the NP and PP of the PP frame behave like selected arguments of the lexical verb: the lexical verb determines both whether they can be implicit or not, and how they are interpreted when they are (indefinite versus definite). In contrast, particular lexical verbs determine whether the first object of the double object construction can be dropped, but not how it is interpreted. All implicit first objects are interpreted as pragmatically recoverable definites. Implicit first objects also do not license sluicing, unlike all other implicit objects. I propose a purely syntactic account of these patterns, using the ApplP analysis of double object constructions (Marantz 1993; Bruening 2001). In the analysis, arguments of functional heads like Voice and Appl can only be implicit in the presence of a Pass(ive) head, but arguments of lexical verbs are left implicit through adjunction of an operator to the lexical V. I show that implicit arguments are not projected as NPs in the syntax, contra works like Landau (2010). The failure of sluicing with implicit first objects is then analogous to the failure of sluicing with active-passive pairs. I also suggest that the identity condition on ellipsis makes reference to maximal projections, not to heads as in Rudin (2019).