cssi/SciSciGPT-SciSciNet huggingface dataset:
Segmented and shielded structures for reduction of thermal expansion-induced tilt errors

The design and prototype tests of a segmented and shielded instrumentation structure, based on tube modules connected by canoe ball type kinematic couplings, are presented with application to a high-precision microscope for biological science experiments. The segmented tube design is shown to be significantly less sensitive to deformation from uneven thermal disturbances than a single tube structure. The gaps between the tube segments relieve thermal strains and restrict axial heat conduction, and the large-radius kinematic couplings provide high thermal resistance interconnects without significantly degrading structural stiffness. Simulation results, based on two- and three-dimensional models of heat conduction, are verified with experimental measurements of prototype structures and are used to predict the dependence of the tilt error on the geometry, boundary conditions, and material properties of the tubular segments. Adding layers of low-cost foam insulation and thin metal shielding to the walls of the structure further improves performance. Kinematic couplings could allow the structure to be disassembled and reassembled without re-calibration, and thus, pre-calibrated tube modules with different components could be easily and quickly interchanged between experiments.
Poor Absorption of High-Dose Posaconazole in Pediatric Bone Marrow Transplant Patients:

OBJECTIVE:To describe the use of high-dose posaconazole in 2 pediatric patients who received bone marrow transplant (BMT) and highlight concerns regarding posaconazole absorption.CASE SUMMARY:We present 2 pediatric BMT patients in whom prescribed high doses of posaconazole (120-300 mg/kg/day for >3 months) provided serum concentrations less than 1 μg/mL. Both patients received posaconazole with other antifungal therapy and surgical debridement for Rhizopus spp. infections after allogeneic BMTs. Various alternative dosing strategies to potentially enhance posaconazole absorption to increase serum concentrations were attempted, including higher daily doses, frequent or continuous oral administration via feeding tube, use of enteral nutrition, and limiting use of acid-blocking agents. During high-dose therapy, frequent posaconazole serum concentration measurement and other monitoring techniques, such as continuous telemetry, were used. While the fungal infections resolved in both patients and no serious adve...
FLUORESCENCE FROM MAJOR AND MINOR BACTERIOCHLOROPHYLL COMPONENTS IN VIVO

— In the photosynthetic bacteria Chromatium, Rhoahpirillum rubrum, and Rhodopseudomonus spheroides the fluorescence of bacteriochlorophyll is probably free of contamination by a “fast” component of delayed emission, judging from the characteristics of the delayed light measured 3 msec after excitation. In Rps. spheroides the pigment P870, associated with photochemical reaction centers, is non-fluorescent in its photochemically active state. Fluorescence of P870 can be induced by either of two agencies that suppress its photochemical activity: exposure to Na2S2O4 and (in a dry chromatophore film) dessication. The yield of fluorescence from the major (light harvesting) component of bacteriochlorophyll in vivo is brought to a common maximum value by conditions that suppress the photochemical activity of P870. In addition to dessication and exposure to Na2S2O4 these conditions include saturating illumination and exposure to K3Fe(CN)6. Of these four treatments only the last two bleach the long wave absorption band of P870. These experiments support the following assertions: (1) P870 traps singlet excitation energy absorbed by the light harvesting BChl; the trapping function of P870 depends on its ability to initiate and participate in photochemistry. (2) Both dessication and exposure to Na2S2O4 suppress the photochemical activity of P870 by blocking an event that proceeds directly from the excited singlet state in P870. (3) The fluoresecence of BChl in vivo is emitted almost entirely by a major (light harvesting) component.
Craft Guilds and Christianity in Late-Medieval England A Rational-Choice Analysis

In late-medieval England, craft guilds simultaneously pursued piety and profit. Why did guilds pursue those seemingly unrelated goals? What were the consequences of that combination? Theories of organizational behavior answer those questions. Craft guilds combined spiritual and occupational endeavors because the former facilitated the success of the latter and vice versa. The reciprocal nature of this relationship linked the ability of guilds to attain spiritual and occupational goals. This link between religion and economics at the local level connected religious and economic trends in the wider world.
Strategy, Beliefs about the Environment, and Performance in a Banking Simulation

This study examined the relationship of strategy and beliefs about the environment to performance outcomes. By means of an assetlliability simulation game, the performance of 64 "banks" was monitored and data were collected on strategic decisions and environmental assessments. Results indicate that systematic differences in performance emerged most sharply when beliefs about the environment differed rather than as a result of differences in strategies.
Ablation Studies of Low-Number Wire Arrays at 200 kA Using A Linear Transformer Driver

We present the preliminary results from the first ablation studies of wire-array z-pinches using a short-pulse linear transformer driver (LTD) providing a current of 200 kA in 150 ns. Laser imaging is used to recover the ablation-flare wavelength for comparison with previous studies and to provide quantitative information on the axial-density variation of this structure. The results are used to determine the general form of the variation of the ablation velocity in the axial direction, and fits to data can infer the range of values required to describe observed modulation. In addition, conical arrays demonstrate the formation and propagation of moderate atomic-number plasma jets comparable with those observed in mega-ampere experiments.
Shakespeare's ‘Other’ Worlds: The Critical Trek

Since the 1980s, Shakespearean criticism has been preoccupied with Shakespeare's representation of ‘other’– non-English or non-European – worlds. That preoccupation has not only revolutionized established understandings of early modern literature and culture; it has also catalyzed important changes in reading practices themselves. The following essay provides a comprehensive overview of these important developments, looking at the critical trajectories leading to and from a still evolving interest in the ‘other’. My purpose is two-fold: (1) to identify the scholarship and questions signal to the interrogation of Shakespeare's ‘other’ worlds; and (2) to address the impact of this line of inquiry on Shakespeare studies.
Drug-Related Pneumonitis During Mammalian Target of Rapamycin Inhibitor Therapy: Radiographic Pattern-Based Approach in Waldenström Macroglobulinemia as a Paradigm

Background.This study determined the frequency of drugrelated pneumonitis during mammalian target of rapamycin (mTOR)inhibitortherapyinWaldenstr¨ ommacroglobulinemia patients and investigated the imaging characteristics and radiographic patterns of pneumonitis. Materials and Methods. A total of 40 patients (23 men, 17 women; 43–84 yearsold) with Waldenstr¨ om macroglobulinemia treated in 2 trials of the mTOR inhibitor everolimus were retrospectively studied. Chest computed tomography (CT) scans during therapy were reviewed for abnormalities suspicious for drug-related pneumonitis by the consensus of three radiologists, evaluating the extent, distributions, and specific findings. The radiographic patterns of pneumonitis wereclassifiedusingtheAmericanThoracicSociety/European Respiratory Society classification of interstitial pneumonia. Results. Drug-related pneumonitis was noted in 23 patients (58%). The median time from the initiation of therapy to the onset of pneumonitis was 5.7 months. Lower lungs were involved in all 23 patients, with a higher extentthan in the other zones (p , .001). The distribution was peripheral and lower in 11 patients (48%) and mixed and multifocal in 10 (44%). The findings were bilateral in 20 patients (87%). Ground glass opacities (GGOs) and reticular opacities were present in all 23 patients, with consolidation in 12, traction bronchiectasis in 2, and centrilobular nodularity in 1.The pattern of pneumonitis was classified as cryptogenic organizing pneumonia (COP) in 16 (70%) and nonspecific interstitial pneumonia (NSIP) in 7 (30%), with overlapping features of COP and NSIP in 7 patients. Conclusion. Drug-relatedpneumonitiswasnotedonCTin58% of Waldenstr¨ om macroglobulinemia patients treated with mTORinhibitortherapy.Mostcommonfindingswerebilateral GGOsandreticularopacities,withorwithoutconsolidation,in peripheral and lower lungs, demonstrating COP and NSIP patterns.The Oncologist 2015;20:1077–1083 Implications for Practice: The present study has demonstrated that drug-related pneumonitis during mammalian target of
Howard Zonana and the Subspecialty Maturation of Forensic Psychiatry

The formal process of specialization and subspecialization in medicine began at the start of the 20th century. Although forensic psychiatry has long held a central place within organized psychiatry, it was not officially recognized as a subspecialty until the end of the 20th century. This milestone was achieved through the efforts of many leaders in the field, and prominent among them has been Howard Zonana, MD. His contributions as a clinician, scholar, leader, and mentor over the past several decades have helped advance the maturation of forensic psychiatry and pave the way for its accreditation as a subspecialty. A review of his career illuminates the core stages of this process.
The Politicization of Abortion and the Evolution of Abortion Counseling

The field of abortion counseling originated in the abortion rights movement of the 1970s. During its evolution to the present day, it has faced significant challenges, primarily arising from the increasing politicization and stigmatization of abortion since legalization. Abortion counseling has been affected not only by the imposition of antiabortion statutes, but also by the changing needs of patients who have come of age in a very different era than when this occupation was first developed. One major innovation—head and heart counseling—departs in significant ways from previous conventions of the field and illustrates the complex and changing political meanings of abortion and therefore the challenges to abortion providers in the years following Roe v Wade.
Generating Customized Transgene Landing Sites and Multi-Transgene Arrays in Drosophila Using phiC31 Integrase

Transgenesis in numerous eukaryotes has been facilitated by the use of site-specific integrases to stably insert transgenes at predefined genomic positions (landing sites). However, the utility of integrase-mediated transgenesis in any system is constrained by the limited number and variable expression properties of available landing sites. By exploiting the nonstandard recombination activity exhibited by a phiC31 integrase mutant, we developed a rapid and inexpensive method for isolating landing sites that exhibit desired expression properties. Additionally, we devised a simple technique for constructing arrays of transgenes at a single landing site, thereby extending the utility of previously characterized landing sites. Using the fruit fly Drosophila melanogaster, we demonstrate the feasibility of these approaches by isolating new landing sites optimized to express transgenes in the nervous system and by building fluorescent reporter arrays at several landing sites. Because these strategies require the activity of only a single exogenous protein, we anticipate that they will be portable to species such as nonmodel organisms, in which genetic manipulation is more challenging, expediting the development of genetic resources in these systems.
The effectiveness of alcoholism screening in an ambulatory care setting

Two hundred and eighty subjects in three ambulatory care clinics participated in this study designed to assess the psychometric properties of the SMAST using DSM-III criteria for alcoholism as the diagnostic standard. Eighty-two subjects (30%) who completed the NIMH Diagnostic Interview Schedule met DSM-III criteria for alcohol abuse and/or dependence. The sensitivity of the SMAST, using the generally accepted weighted cut-off score of five or greater, was .56 and the specificity was .83. An unweighted cut-off score of two or greater produced a sensitivity of .72 and a specificity of .64. The results of this study suggest that, when the SMAST is used for screening in an ambulatory care clinic population, the optimum balance of sensitivity and specificity is achieved using an unweighted cut-off score of two or greater. In addition, the alcohol subscale of the Diagnostic Interview Schedule was easy to administer and should be considered for use as the diagnostic standard in clinical settings.
Medieval visions and contemporary hallucinations.

The hallucinations of 23 patients with predominantly religious themes were compared with descriptions of visions from the Middle Ages. Although there were many points of similarity between the two classes of phenomena, none of the medieval visionaries was identified as mentally ill. The role of cultural norms in determining the attribution of mental illness, and the limitations of Euro-American criteria of psychoses, are discussed in the light of these findings.
RE: “MATERNAL ASTHMA MEDICATION USE AND THE RISK OF GASTROSCHISIS”

The objective of this study was to examine the association between maternal asthma medication use during the periconceptional period and the risk of gastroschisis. In this case-control study, the authors used data on deliveries enrolled in the National Birth Defects Prevention Study (1997-2002) from eight collaborating centers. The cases included 381 infants with isolated gastroschisis, and the controls were 4,121 liveborn infants without malformations. The asthma medications used during the periconceptional period (1 month prepregnancy through the third pregnancy month) were divided into two groups, antiinflammatory and bronchodilator, and analyzed separately. Users of multiple asthma medications during the periconceptional period were also examined. Logistic regression was used to estimate odds ratios and 95% confidence intervals while controlling for maternal age, race/ethnicity, education, smoking, folic acid/vitamin use, and other vasoactive medications. Maternal bronchodilator use showed an elevated statistically significant risk of gastroschisis (adjusted odds ratio = 2.06, 95% confidence interval: 1.19, 3.59). No significant association was found between maternal use of asthma antiinflammatory medications and gastroschisis. Because information on maternal asthma status/severity was not available, the effects of disease on the risk of gastroschisis cannot be ruled out. Additional research is needed in determining whether a real risk exists and for guiding asthma treatment.
A Framework for Describing Variations in State Early Intervention Systems.

As part of the National Early Intervention Longitudinal Study, information about the early intervention service systems in the 20 participating states was gathered. This article organizes this information into dimensions of a framework for describing early intervention systems at the state and local levels. Information collected indicates that considerable variation exists on all dimensions of the framework. Descriptive information is presented about how local jurisdictions are defined, eligibility criteria, what agencies are involved in early intervention, and models of intake and of service coordination, including vignettes for selected states. Research on the significance of this variation for how families experience early intervention is needed if better systems are to be implemented. Frameworks for describing early intervention systems are a necessary first step to this line of research. Future analyses from this study will look at the relationship between early intervention systems, services provide...
Inclusion of young children with special needs in early childhood education: The research base

Abstract Increasingly, early childhood programs include children with disabilities and typically developing children. The purpose of this paper is to review the recent empirical literature that underlies the practice of inclusion at the early childhood level in order to provide a context for the research articles appearing in this issue of ECRQ. We first describe the definitions of inclusion, rationales for inclusive classes, and demographics of inclusive programs and staff. Using Bronfenbrenner's ecological systems theory as a conceptual framework, we review research related to variables proximal to the program (i.e., microsystem and mesosystem levels) such as classroom practices, children's social interactions, teacher beliefs, and professional collaboration. Next, we examine research associated with variables occurring more distally from the classroom program (i.e., exosystem and macrosystem levels): families' perspectives, social policy, community and culture. We conclude this review with an examination of research that illustrates the influence of variables a one level of the ecological system on those occurring at a different levels and recommend directions for future research.
Quantum dot photonic crystal nanocavities: Transition from weak to strong coupling and nonlinear emissions

Photonic crystal slab nanocavities containing one layer of quantum dots have exhibited: strong coupling to a single quantum dot; tuning by condensation of xenon gas; linewidth broadening due to ensemble dot absorption; gain and lasing.
The Informal Sector In Sub-Saharan Africa: Out Of The Shadows To Foster Sustainable Employment And Equity?

Over the past twenty years or so, there has been a debate that basically asks “…whether the informal sector should really be seen as a marginalized, ‘survival’ sector, which mops up excess or entrenched workers, or as a vibrant, entrepreneurial part of the economy which can stimulate economic growth and job creation.” (African Union 2008). This paper argues the latter. Further, this paper argues that employment in the informal sector is no longer a journey, but has become the destination of many. If the aim is to create jobs and reduce poverty, the informal sector must be included in the debate. Indeed, this paper recommends that the debate about the advantages of formal sector vs. the informal sector needs to end. Governments need to unequivocally recognize and admit the importance of the informal sector and finds ways to encourage its growth. They also need, at the same time, to decide how to strengthen the formal sector and extend benefits to those in the informal sector, while removing barriers to the formal sector to allow more to participate. Specifically, there are at least five major areas where changes need to be made: 1) Establish an enabling environment and supportive regulatory framework, 2) Provide access to appropriate training, 3) Improve basic facilities and amenities and infrastructure, 4) Increase ability to obtain property title and access to credit, and 5) Improve national databases and establish uniform standards.
Feminist scholarship and the American Academy

The decades of the 1960s and 1970s were ones of social and political change in the United States. They were characterized by the civil rights struggles of African Americans, protests against American involvement abroad, particularly in Southeast Asia, and the rebirth of the women’s movement. These movements questioned established authority and many cherished institutional values. A significant number of those involved in the social and political activism of those decades were professors and students who challenged their colleges and universities to respond to and participate actively in changing oppressive social conditions. The 1960s and 1970s were times of intellectual ferment on the nation’s campuses, as higher education was charged with complicity in serving to keep women and minorities in subservient positions in society, and in developing the technology and expertise to maintain American imperialism and adventurism abroad.
Astrostatistics: A Brief History and View to the Future

Humans have long sought to understand astronomical events through the use of mathematical relationships. Ancient monuments were constructed to be aligned with stellar positions at given times of the year, and eclipses were assiduously recorded and predicted for a variety of reasons. In pre-scientific times priests and astrologers attempted to predict astronomical relationships for the purpose of understanding the minds of the gods. It was not until the 5th century BCE that a small group of philosophers living in the area of the Aegean Sea began to value understanding nature for its own sake. Many historians argue that science in fact began during this period. The event that some signal as the beginning of science was the prediction of a total solar eclipse by Thales of Miletus in 585 BCE. By using his knowledge of past eclipses and their locations, Thales predicted that the eclipse would occur in central Lydia close to May 28th of that year. As it happened, the Lydians were in battle against the Medes. The celestial event resulted in a cessation of the war, and a widespread recognition of Thales as a Sage.
IMPLICIT FEEDBACK: USING BEHAVIOR TO INFER RELEVANCE

The chapter presented a framework for understanding and studying how behavior can be used as implicit relevance feedback. This included a classification and discussion of behaviors that have been used as implicit relevance feedback, a general discussion and characterization of implicit feedback research, and a presentation of example studies to illustrate how such studies have been conducted and how feedback has typically been measured and used. Finally, this chapter presented a discussion of key issues and problems associated with implicit feedback research and identified challenges for future research. The use of behavior as implicit relevance feedback is an exciting and promising approach to personalizing IR interactions. Although more effort needs to be made to fully understand how behaviors can be used as implicit relevance feedback, current research efforts offer a promising start.
On entire and meromorphic solutions of

We describe the entire and meromorphic solutions of partial differential equations of the form where k, m>1, λ in , and
5-Hydroxytryptamine in mast cells.

Summary5-Hydroxytryptamine as well as histamine and heparin was demonstrated to be present in purified mast cells from the peritoneal washings of rats. The material was identified by bioassay and chromatography. The concentration of 5-hydroxytryptamine found in isolated mast cells agreed with that found by indirect means in the mast cells of the subcutaneous areolar tissue of rats. Implications of this finding are briefly discussed.
Preimplantation human embryonic development from polypronuclear eggs after in vitro fertilization

The occurrence of grossly normal-appearing morula stage human embryos (8- to 12-cell) that developed from eggs fertilized in vitro containing three pronuclei is described. Serial section analysis by transmission electron microscopy demonstrated that 25% of the blastomeres were multinucleate, with as many as five deoxyribonucleic acid-containing nuclei (determined by fluorescence microscopy) in a single cell. Light and electron microscopy indicated that normal cortical and zona reactions had taken place. Fine-structural development of the cytoplasm was characteristic of morula stage human embryos. The results suggest the need to determine pronuclear number prior to syngamy and are discussed with respect to the notion that human embryos may have the capacity to develop normally in spite of the presence of abnormal cells.
Effects of sowing date and planting site on grain quality and RVA profiles of Nanjing 46,a popular cultivar in japonica rice( Oryza sativa L. )

To study the effects of different sowing dates and sites on grain quality and rapid viscosity analyzer(RVA) profiles of japonica rice Nanjing 46,a total of 7 sowing dates and 5 sites were set.The results showed that with the delay of sowing date,the milling quality of Nanjing 46 increased first and then reduced,the appearance quality went up and cooking and edible quality went down.With the sowing sites moving southward,the rice milling quality,appearance quality and cooking and edible quality of Nanjing 46 decreased first and then increased.Grain traits responded variably to the sowing dates and sites.The brown rice rate,grain width,grain length,length / width,milled rice rate and head milled rice rate were less affected,while the chalky rice rate and chalkiness degree were affected largely.The gelatinization temperature,protein content,amylose content,gel consistency and eating value were in-between.The RVA profile analysis revealed that,the breakdown value,setback value and pasting temperature were affected by the sowing date and geographical environment.The peak viscosity,hot viscosity,final viscosity and peak time were influenced more by geographical environment.With the delay of sowing date,peak viscosity,hot viscosity,final viscosity,setback value and pasting temperature reduced first and then increased,the breakdown value changed inversely,and the peak time stayed stable.With the decrease of latitude,the peak viscosity,hot viscosity,breakdown value and final viscosity decreased first and then increased,the setback value deereased,peak time shortened,and pasting temperature increased.
Creating a Bully-free Environment in Physical Education

This article describes how teachers can develop positive physical self-perceptions for all children and eliminate negative associations with physical education by proactively designing and implementing a pro-social and bully-free learning environment.
Gastroesophageal Reflux in Children

This continuing feature will focus on recent advancements in the areas of pediatrics and neonatal pharmacology and on methods for reducing medication error risk in this patient population. Most pharmacological agents are designed with the adult in mind, and there is little literature-based data from which to derive dosing schedules and proper drug administration techniques for the pediatric and neonatal patient. Moreover, pharmacological response in this group is not well understood. We hope that this feature will help you provide pharmaceutical care to this high-risk population. Direct questions or comments to Stuart Levine, PharmD, at slevine@nemours.org.
Smart Wearables or Dumb Wearables?: Understanding how Context Impacts the UX in Wrist Worn Interaction

Recent advances in technology fostered the commercialization and usage of wearable devices. Among diverse form factors, wrist worn devices stand out. Benefitting from a conventional format and easy access, wrist worn devices, such as smart watches and fitness trackers, have been gaining popularity. While their continuous usage and close contact with the human body enable various applications, their limited computational resources summed with continuous changes in the context of use challenge designers in providing effective interactive solutions for end users. Seeking to understand how the context of use impacts the user experience and interaction with ten popular wrist worn wearables, in this study we analyzed the users' feedback: 545 users' comments were collected from Amazon, coded and aggregated. Based on the users' feedback, we identify 31 major problems that are currently faced in wrist worn interfaces. The analyses of the users' feedback led to a discussion about the causes and severity of those problems, and also to the definition of a set of design implications aimed at improving the user interaction with the next-generation wrist worn wearables.
A full-duplex transceiver front-end employing inverse class-D power amplifiers

A full-duplex transceiver front-end architecture that employs inverse class-D switching power amplifiers is described. An LC phase-shift network is employed between the receiver port and the antenna port. By proper phasing of the switching devices, the transmitted signal can add constructively at the antenna port while canceling at the receiver port, thereby enabling full-duplex operation. The motivation in using switch-based power stages is to reduce the degradation in receiver noise figure, that can result from the noise of devices in the transmitter. The use of a bandpass filtering network to reduce loss in efficiency arising from harmonics, and its impact on receiver noise figure and rejection are described, and the maximum efficiency of the transmitter is analyzed. Assuming inductors with a quality factor of 50, switches with series on-resistance of 5 Ω and noiseless receiver port matching, this architecture demonstrates 0.4 dB NF and 58% transmitter efficiency, with 28 dB rejection of the transmitted signal at the receiver port, in simulation. The 20-dB rejection bandwidth is approximately 20 MHz.
The effects of different types of text and individual differences on view complexity about genetically modified organisms

ABSTRACTView change about socio-scientific issues has been well studied in the literature, but the change in the complexity of those views has not. In the current study, the change in the complexity of views about a specific scientific topic (i.e. genetically modified organisms; GMOs) and use of evidence in explaining those views was examined in relation to individual factors and type of text (informational, persuasive, or narrative). Undergraduate students completed measures of their prior views about GMOs their epistemic beliefs about the nature of science, and activities related to food consumption. Participants then read either an informational, persuasive, or narrative passage about GMOs and again answered a question related to their views about GMOs. Participants who read the persuasive passage decreased in the complexity of their views, while those who read the narrative and expository passage increased in the complexity of their views. Additionally, while cultural activities related to the complex...
5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores.

Citation: Opoku-Acheampong, A. B., Henningson, J. N., Beck, A. P., & Lindshield, B. L. (2017). 5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores. Plos One, 12(5). doi:10.1371/journal.pone.0175874
Fragility risks of low latency dynamic queuing in large-scale clouds: Complex system perspective

Economic, reliability, and low latency benefits of the cloud computing model are the result of a high level of dynamic resource sharing, made possible by a high degree of system interconnectivity. This paper suggests a more nuanced view of the effect of interconnectivity and resource sharing since interconnectivity may contribute to system fragility, which is associated with a possibility of abrupt/discontinuous system transition to a persistent overloaded regime with unacceptably high delays. This possibility is a result of the same system interconnectivity, which enables not only desirable but also undesirable load transfer throughout the networked system. Our results indicate that benefits of dynamic queuing disciplines, including low latency, can be realized provided that the relevant systemic risks of undesirable contagion are eliminated or mitigated. Due to the intractability of conventional performance models of large-scale interconnected systems, we use the “Complex Systems” methodology, e.g., a mean-field approximate performance model.
How well do various types of support buffer psychological distress among transgender and gender nonconforming students

Background: Transgender and gender nonconforming (TGNC) individuals experience an increased prevalence of many psychological disorders, leading many to reach out for support from family, friends, mental health professionals, and religious or community networks. Nonetheless, experiences seeking support are often negative, and many psychotherapists report feeling underprepared to work with TGNC clients. To better understand the experiences of TGNC individuals and better equip psychotherapists in their work with TGNC clients, we investigate which sources of support most successfully buffer psychological distress among TGNC individuals. Aims: This study aims to identify differences in levels of various types of support (social, family, religious, and living-situation) between cisgender and TGNC individuals and examine how these types of support may or may not buffer psychological distress among TGNC individuals. Method: We used a United States national sample of 3,090 students (1,030 cisgender men; 1,030 cisgender women; 349 transgender; 681 endorsing another gender identity) from the Center for Collegiate Mental Health 2012-2015 database which provided basic demographic information through the Standardized Data Set. Psychological distress was measured through the Counseling Center Assessment of Psychological Symptoms 34-item questionnaire. Results: TGNC individuals reported more distress, less family support, more social support, and less frequent religious affiliation than cisgender men and women. Family and social support emerged as the strongest predictors of distress for both TGNC and cisgender individuals. Though religious affiliation and living on-campus buffered distress among cisgender students, they did not buffer distress among TGNC students. Conclusion: Our study highlights disparities in distress and support between TGNC and cisgender individuals. We found that although religious affiliation and on-campus living are beneficial for cisgender students, neither systematically buffers distress for TGNC students. These findings illustrate the impact minority stress and systemic discrimination may have on TGNC individuals and provide suggestions for therapeutic intervention in work with TGNC individuals.
Adam Mickiewicz: Poland’s Romantic Ambassador to the Court of Realism

The life and achievements of Mickiewicz and Tolstoy have often been compared, and there are, indeed, many similarities between them: both were great artists; both of them were endowed with passionately sensual natures; both were deeply devoted to moral self-perfection; each, at a certain moment of his life, abandoned his art for causes which he considered to be superior; both went through great moral defeats and falls, but both were moved during their whole lives by a powerful spiritual dynamism which characterized their existence and work; both show not only what I would call the Heraclitean element—that passion for movement—but constant evolution, ascension, and to use another term, transformation.
Generating Complex Astronomy Workflows

Astronomy has a rich heritage of discovery using image data sets that cover the full range of the electromagnetic spectrum. Image data sets in one frequency range have often been studied in isolation from those in other frequency ranges. This is mostly a consequence of the diverse properties of the data collections themselves. Images are delivered in different coordinate systems, map projections, spatial samplings, and image sizes, and the pixels themselves are rarely co-registered on the sky. Moreover, the spatial extent of many astronomically important structures, such as clusters of galaxies and star formation regions, is often substantially greater than that of individual images.
Effects of Interaction Between Stress and Temperature on Ultrasound Velocity

The work described here is part of a program to explore the possibility of employing a new concept for ultrasonic nondestructive evaluation of subsurface residual stress in metals. Theory indicates its potential applicability to characterization of stress to depths of 1–2 cm or more. The method employs a measurement of time variations in velocity in response to the inducement of time-varying thermal gradients within the stress region. The physical principle, as discussed below, is an interaction between stress, temperature and velocity.
OR31: CASE STUDY: DOA: DONOR ORIGINATING ANTIBODY; A CASE OF PASSIVE ANTIBODY TRANSFER

Aim To investigate the unexplained HLA antibody specificity observed in a post-transplant serum specimen from a lung transplant recipient. Methods Antibody (Ab) evaluation was performed using phenotype and single antigen panels tested on the Luminex ® platform (Lifecodes, One Lambda). Results Patient JD is a 47 year old female with a history of cystic fibrosis. The patient received a bilateral lung transplant on October 3, 2013 from a deceased donor at Johns Hopkins Hospital. A serum specimen drawn immediately prior to transplant was negative for IgG, HLA class I-specific antibody and demonstrated very weak reactivity for IgG, class II-specific antibody. At day T + 4, a post-transplant serum specimen exhibited a substantial antibody increase. Although the timing of antibody appearance indicated an anamnestic response, the specificity was inconsistent with the patient’s historical HLA-specific antibody and appeared to be specific for non-donor antigens. Repeated testing and testing with additional assays confirmed the initial results. Transplanted lungs can be accompanied by substantial donor lymphoid tissue. We therefore tested donor serum for HLA specific antibody. Tests of the deceased donor serum revealed strong HLA-specific antibody nearly identical to the pattern observed with the recipient’s Day T + 4 post-transplant serum. Upon further investigation, we found that, in fact, the donor has been the recipient of a kidney transplant. The deceased donor’s previous transplant information was obtained. The antibody detected in the donor serum was specific for multiple mismatched antigens present in the HLA phenotype of the deceased donor’s kidney transplant. Tests of sera obtained monthly from the lung recipient have shown a steady reduction in antibody strength and breadth. The pattern and the course of the antibody over time suggest that the antibody was of donor origin. Conclusion In this case, having access to the deceased donor’s serum allowed us to investigate the anomalous HLA-specific antibody testing results. Retrieving the deceased donor’s past medical history listed in UNET provided evidence of the transfer of donor antibody-producing cell to the patient JD.
Forward head posture (FHP) angle and plantar pressure resulting from oscillatory stimulation training of the shoulder joint: A randomized controlled trial.

BACKGROUND Oscillatory stimulation provides strong sensory stimulation, which can activate muscle spindles, strengthening proprioceptive sense and, therefore, helping to strengthen the muscles involved in posture stability. OBJECTIVE This study aimed to investigate the difference in average distribution of plantar pressure resulting from changes in the forward head position (FHP) angle caused by controlling muscle activity in the neck and shoulders through Bodyblade. METHODS The subjects were divided into an experimental group (Bodyblade, n= 15) and a control group (general physiotherapy, n= 15). Eighteen sessions of exercise were implemented. Craniovertebral angle (CVA) and cranial rotation angle (CRA) were measured to evaluate the change of FHP. The Gaitview AFA-50 (Alfoots Co, Korea) was used to measure the plantar pressure distribution. RESULTS The experimental group showed a larger increase in CVA than the control group (p< 0.05). Only the experimental group showed a significant decrease in CRA (p< 0.05).Both the anterior pressure and posterior pressure showed a significant improvement only in the experimental group (p< 0.05). The experimental group showed a larger increase in anterior/posterior ratio than the control group (p< 0.05). CONCLUSIONS Bodyblade improves the angle of FHP, thus positively affecting the average ratio of plantar pressure.
Ultra-Rapid Determination of Material Removal Rates Based Solely on Tribological Data in Chemical Mechanical Planarization

Single-run Stribeck+ curves are constructed using real-time, high-frequency, shear force and normal force data from the wafer-slurry-pad interface during copper and cobalt (on ILD wafers) CMP in conjunction with multiple slurries, pads and conditioning discs at various pressures and relative velocities. To avoid having to perform actual polishing experiments to obtain blanket film removal rates, "big data" sets from the same Stribeck+ curves are used to construct new "Kinetic" curves to help infer relative blanket wafer removal rates. The "Kinetic" curves, which are based on the assumption that material removal is Prestonian, are eventually validated with actual removal rate studies involving different wafer types processed at various pressures-velocity combinations with the same pads, conditioning discs and slurries. A strong correlation is seen between the actual and "inferred" removal rates which renders credibility to our new ultra-rapid and ultra-low-budget approach for determining removal rates that does not require any wafer polishing nor any film thickness metrology.
HiCNN: a very deep convolutional neural network to better enhance the resolution of Hi-C data.

Motivation High-resolution Hi-C data are indispensable for the studies of three-dimensional (3D) genome organization at kilobase level. However, generating high-resolution Hi-C data (e.g. 5 kb) by conducting Hi-C experiments needs millions of mammalian cells, which may eventually generate billions of paired-end reads with a high sequencing cost. Therefore, it will be important and helpful if we can enhance the resolutions of Hi-C data by computational methods. Results We developed a new computational method named HiCNN that used a 54-layer very deep convolutional neural network to enhance the resolutions of Hi-C data. The network contains both global and local residual learning with multiple speedup techniques included resulting in fast convergence. We used mean squared errors and Pearson's correlation coefficients between real high-resolution and computationally predicted high-resolution Hi-C data to evaluate the method. The evaluation results show that HiCNN consistently outperforms HiCPlus, the only existing tool in the literature, when training and testing data are extracted from the same cell type (i.e. GM12878) and from two different cell types in the same or different species (i.e. GM12878 as training with K562 as testing, and GM12878 as training with CH12-LX as testing). We further found that the HiCNN-enhanced high-resolution Hi-C data are more consistent with real experimental high-resolution Hi-C data than HiCPlus-enhanced data in terms of indicating statistically significant interactions. Moreover, HiCNN can efficiently enhance low-resolution Hi-C data, which eventually helps recover two chromatin loops that were confirmed by 3D-FISH. Availability and implementation HiCNN is freely available at http://dna.cs.miami.edu/HiCNN/. Supplementary information Supplementary data are available at Bioinformatics online.
Athens Music Project Oral History Collection, Richard B. Russell Library for Political Research and Studies, University of Georgia

The Athens Music Project Oral History Collection, directed by the Russell Library Oral History Program at the University of Georgia (UGA), is part of the Athens Music Project (AMP), co-directed by ...
Keeping the paschal lamb: Exodus 12.6 and the question of sacrifice in the Passover-of-Egypt:

The paschal prescription in Exodus 12.3-6—attributed to the Priestly Source—that requires the Israelites to keep an animal four days prior to slaughtering it is an enigmatic episode unparalleled in...
Developing and Implementing a Cybersecurity Course for Middle School.

Investing in raising a generation with more security-aware minds is vital in preventing many of the security incidents that threaten individuals, organizations, businesses and nations today. In addition, there is a high need for well-trained cybersecurity professionals to protect our networks, computer systems, and infrastructure. Early exposure to basic cybersecurity concerns and concepts is key to developing awareness, piquing student interest, and laying foundation for more complex skill development. In this work, authors present their work developing a middle school cybersecurity curriculum for U.S. grade 8 students. This includes standards, objectives, and lessons for implementation within a year-long business and computer science course. The authors also share their experience and results from piloting the curriculum with nearly sixty grade 8 students in two classes at a Title I middle school in Columbus, GA during the 2017–2018 school year. A comparison of pre and post test results on the content show a significant growth in mastery of key cybersecurity concepts. In addition, artifacts from the course indicate an increased student interest in cybersecurity.
Cell-free transcription in Xenopus egg extract.

Soluble extracts prepared from Xenopus eggs have been used extensively to study various aspects of cellular and developmental biology. During early egg development, transcription of the zygotic genome is suppressed. As a result, traditional extracts derived from unfertilized and early stage eggs possess little or no intrinsic transcriptional activity. In this study, we show that Xenopus nucleoplasmic extract (NPE) supports robust transcription of a chromatinized plasmid substrate. Although prepared from eggs in a transcriptionally inactive state, the process of making NPE resembles some aspects of egg fertilization and early embryo development that lead to transcriptional activation. With this system, we observed that promoter-dependent recruitment of transcription factors and RNA polymerase II leads to conventional patterns of divergent transcription and pre-mRNA processing, including intron splicing and 3′ cleavage and polyadenylation. We also show that histone density controls transcription factor binding and RNA polymerase II activity, validating a mechanism proposed to regulate genome activation during development. Together, these results establish a new cell-free system to study the regulation, initiation, and processing of mRNA transcripts.
The Bakhvalov mesh: a complete finite-difference analysis of two-dimensional singularly perturbed convection-diffusion problems

A linear two-dimensional singularly perturbed convection-diffusion boundary-value problem is considered. The problem is discretized by the upwind finite-difference method. The analysis of this method on Shishkin-type meshes has been well-established, but the discretization mesh in this paper is the original Bakhvalov mesh, introduced in 1969 as the first layer-adapted mesh. We analyze the error of the numerical solution in the maximum norm and prove first-order pointwise accuracy, uniform in the perturbation parameter. This is the first complete analysis of this kind for two-dimensional convection-diffusion problems discretized on the Bakhvalov mesh. Our numerical experiments validate the theoretical analysis.
The written and oral justifications of mathematical claims of middle school pre-service teachers

Teaching meaningful and productive mathematical argument in school requires teachers who are comfortable with diverse forms of mathematical justification. This study examines the written and oral j...