cssi/SciSciGPT-SciSciNet huggingface dataset:
Role of resonances in nonleptonic hyperon decays

We examine the importance of resonances for the non-leptonic hyperon decays in the framework of chiral perturbation theory. Lower lying resonances are included into the effective theory. Integrating out the heavy degrees of freedom in the resonance saturation scheme generates higher order counterterms in the effective Lagrangian, providing an estimate of the pertinent coupling constants. A fit to the eight independent decay amplitudes that are not related by isospin symmetry is performed and reasonable agreement for both s- and p- waves is achieved.
Factors Influencing the Microbiological Degradation of Choline and Tryptophan in Man

SummaryAntibacterial compounds, including penicillin G and phthalylsulfathiazole or a combination of these drugs produced variable suppression of urinary trimethylamine (TTMA) and indican output in normal male subjects. Three men with rapid intestinal transit time and low initial indican values exhibited markedly reduced TTMA and indican excretion in response to either drug alone and prolonged depression with combined drug treatment; while four men with prolonged intestinal transit time and high initial indican values showed less suppression of TTMA and indican excretion with sulfa or penicillin G alone and only transient suppression of indican and TTMA with combined treatment. It has been concluded that intestinal stasis is a major determinant of the escape of intestinal microflora from the action of these drugs.
Eye torsion and the apparent horizon under head tilt and visual field rotation.

Two different experimental manipulations, namely head tilt and the viewing of a visual display rotating around the line of sight, induce torsional displacements of the eyes and a tilting of the apparent horizon. The present study examines the routes by which visual (field rotation) and otolith-proprioceptive (head tilt) sources of afference influence horizon judgments. In particular, the relationship between torsional eye movements and horizon estimates is addressed. The results indicate that visual and otolith-proprioceptive information sum directly in their influence on eye torsion, but interact more complexly in horizon estimates, indicating a dissociation of their central determinants.
Carbon dioxide, water vapor and sensible heat fluxes over a tallgrass prairie

Fluxes of CO2, water vapor and sensible heat were measured in a grassland ecosystem near Manhattan, Kansas, employing the eddy correlation technique. The vegetation at this site is dominated by big bluestem (Andropogon gerardii), switchgrass (Panicum virgatum), and indiangrass (Sorghastrum nutans). Diurnal patterns of the energy budget components and CO2 fluxes are evaluated on a few selected days. Influence of high atmospheric evaporative demand and low availability of soil water are examined on (a) energy partitioning, and (b) the magnitudes and patterns of atmospheric carbon dioxide exchange.
Recovery kinetics of photochemical efficiency in winter stressed conifers: the effects of growth light environment, extent of the season and species

Evergreens undergo reductions in maximal photochemical efficiency (F(v)/F(m)) during winter due to increases in sustained thermal energy dissipation. Upon removing winter stressed leaves to room temperature and low light, F(v)/F(m) recovers and can include both a rapid and a slow phase. The goal of this study was to determine whether the rapid component to recovery exists in winter stressed conifers at any point during the season in a seasonally extreme environment. Additional goals were to compare the effects of species, growth light environment and the extent of the winter season on recovery kinetics in conifers. Four species (sun and shade needle) were monitored during the winter of 2007/2008: eastern white pine (Pinus strobus), balsam fir (Abies balsamea), Taxus cuspidata and white spruce (Picea glauca). F(v)/F(m) was measured in the field, and then monitored indoors at room temperature and low light for 6 days. The results showed that all species showed a rapid component to recovery in early winter that disappeared later in the season in sun needles but was present in shade needles on most days monitored during winter. There were differences among species in the recovery kinetics across the season, with pine recovering the most slowly and spruce the most quickly. The results suggest an important role for the rapidly reversible form of energy dissipation in early winter, as well as important differences between species in their rate of recovery in late winter/early spring which may have implications for spring onset of photosynthesis.
Surfactant therapy and spontaneous diuresis

The effect of artificial surfactant therapy on renal function and the onset of spontaneous diuresis was prospectively evaluated in 19 infants with hyaline membrane disease in a double-blind, controlled study. Twelve infants were in the surfactant group; seven infants received placebo (0.9% saline solution). There was no difference in the time of onset of spontaneous diuresis (as defined by output ≥80% of intake). The glomerular filtration rate, determined by endogenous creatinine clearance, was also similar in the surfactant- and placebo-treated infants during the first 3 days of life. The fractional excretion of sodium was significantly higher in the placebo group at 24 hours and 36 hours. Infants in the placebo group had a higher negative sodium balance than those in the surfactant group. Ventilatory status improved significantly soon after surfactant treatment, as evidenced by improvement in the alveolar/arterial oxygen pressure ratio and by a lower mean airway pressure. These data suggest that ventilatory status can be improved without diuresis; the factors that regulate diuresis are multiple and not fully understood.
Enantiopure, octadentate ligands as sensitizers for europium and terbium circularly polarized luminescence in aqueous solution.

Tb and Eu complexes of enantiopure ligands with a new modular design show strong overall luminescence and CPL activity in aqueous solution.
Digital rat brain: A computerized atlas

Digital brain mapping provides the techniques required for 3 dimensional (3D) reconstruction and display. This paper describes work which extends the data published in the Paxinos and Watson (1982) atlas of the rat brain to a computerized form. The product of these experiments is a 3D digital neuroanatomic atlas. The data were transformed from 2D outlines to 3D volumes each associated with a specific neuroanatomic structure. The system which manages this transformation also provides tools to manipulate the composition, orientation and appearance of the displays interactively.
A Case Report of a Branched Oviduct

Abstract In a series of experiments in which Depotestosterone (cyclopentylpropionate) was used to induce modification of the right gonad and gonoduct in female chicks, an unusual left oviduct condition was discovered in one of the treated specimens. In our experiments fertile eggs which had been incubated for 5 to 7 days were treated with doses of 0.02, 0.05, or 0.10 c.c. of testosterone in oil. The oil and hormone mixture was injected into the air space of the egg. Approximately 400 embryos were treated with testosterone and autopsied just prior to or at hatching time. There was a slightly delayed development in these embryos and the female embryos exhibited delayed regression of the right oviducts. In the case being reported here, embryo #8599L was examined after 21 days of incubation. The left ovary was approximately 2.0 mm. wide and 7.0 mm. long. The left oviduct was bifurcated; the division occurring anteriorly…
Convexity and decomposition of mean-risk stochastic programs

Traditional stochastic programming is risk neutral in the sense that it is concerned with the optimization of an expectation criterion. A common approach to addressing risk in decision making problems is to consider a weighted mean-risk objective, where some dispersion statistic is used as a measure of risk. We investigate the computational suitability of various mean-risk objective functions in addressing risk in stochastic programming models. We prove that the classical mean-variance criterion leads to computational intractability even in the simplest stochastic programs. On the other hand, a number of alternative mean-risk functions are shown to be computationally tractable using slight variants of existing stochastic programming decomposition algorithms. We propose decomposition-based parametric cutting plane algorithms to generate mean-risk efficient frontiers for two particular classes of mean-risk objectives.
CNS neuronal focal adhesion kinase forms clusters that co-localize with vinculin

Focal adhesion kinase (FAK) is a non-receptor protein tyrosine kinase that appears to play a central role in integrin-mediated signal transduction in non-neuronal cells, linking the extracellular matrix to the actin-based cytoskeleton at focal adhesion contacts. Biochemical analysis has revealed the presence of FAK immunoreactivity in cells of neuronal lineage (Zhang et al., 1994) and in the CNS (Burgaya et al. 1995; Grant et al., 1995). In the current work, we have examined the immunodistribution of FAK in nerve cell cultures and tissue sections from the rat CNS. Cultures of B103 CNS neuroblastoma cells and primary cultures of hippocampal neurons both showed abundant FAK immunoreactivity in nerve cell bodies. Immunoreactivity also extended into neurites and growth cones. The most striking feature of FAK distribution was the presence of short, punctate clusters of high FAK concentration. These FAK clusters were maintained in triton-extracted cell ghosts, indicating association with the cytoskeleton. Double-label confocal imaging showed that clusters of FAK coincided with clusters of vinculin, another actin-associated signal transduction molecule implicated in control of growth cone motility. Data from hippocampal sections verified the presence of FAK in adult neurons where it was enriched in somato-dendritic domains and showed a non-uniform distribution. Quantitative FAK immunoprecipitation to compare adult with embryonic brain showed a 7-fold developmental down-regulation of FAK and a 21-fold down-regulation of FAK TyrP. The data suggest that neuronal FAK may participate in signal transduction complexes relevant to neuronal morphogenesis and plasticity.
Generativity Abilities Predict Communication Deficits but not Repetitive Behaviors in Autism Spectrum Disorders

Individuals with Autism Spectrum Disorders (ASD) often demonstrate impaired generativity that is thought to mediate repetitive behaviors in autism (Turner in J Child Psychol Psychiatry, 40(6):839-849, 1999a). The present study evaluated generativity in children with and without ASD via the use-of-objects task (Turner in J Child Psychol Psychiatry, 40(2):189-201, 1999b) and an Animals Fluency Task (Lezak in Neuropsychological assessment. Oxford University Press, Oxford, 1995). Groups differed significantly on two of four metrics from the Animals Fluency Task and two of seven metrics from the Use of Objects task. In the ASD sample, no significant relations were found between generativity and repetitive behaviors. Significant relations were found, however, between performance on the Animals Fluency Task and communication symptoms. Results replicate reports of generativity deficits in ASD and suggest that impaired generativity may reflect communication deficits that are characteristic of the disorder.
The Asian factor: Methodological barriers to the study of Asian gangs and organized crime

This paper examines methodological barriers that confront the study of Asian criminal gangs and organized crime. Researchers need to address definitional issues, appreciate the pluralistic nature of Asian communities, incorporate region as a unit of analysis, enhance the reliability of interviewees’ responses, and recognize the impact of news media on the public perception of Asian crime. A research agenda is offered to deal with these issues in future research endeavors.
Should postmenopausal women with rheumatoid arthritis who are starting corticosteroid treatment be screened for osteoporosis? A cost-effectiveness analysis.

Objective. To evaluate the cost-effectiveness of different strategies for preventing corticosteroid-induced osteoporosis. Methods. Simulated cohorts of postmenopausal women with rheumatoid arthritis (RA) starting corticosteroid treatment were examined. A Markov decision analysis model was developed to compare different management strategies, including watchful waiting, screen and treat, and empirical treatment. Treatment thresholds for the screen and treat strategy were varied from bone mineral density (BMD) T scores <-1.0 to BMD T scores < -4.0. Results. Compared with a watchful waiting approach, the incremental cost-effectiveness ratio for a strategy of screen and treat with alendronate at a BMD T score of <-1.0 was $92,600 per quality-adjusted life year (QALY) gained. This result was sensitive to the cost and efficacy of osteoporosis therapy and, importantly, to the treatment threshold. At a treatment threshold of a BMD T score <-2.5, the incremental cost-effectiveness ratio of screening and treating was $76,100 per QALY. None of these results differed substantially for women taking estrogen replacement therapy. Conclusion. The incremental cost-effectiveness ratio of a strategy of screening and treating postmenopausal female RA patients with BMD T scores of <-1.0, compared with watchful waiting, was greater than that of other well-accepted medical interventions. The cost-effectiveness ratios were more acceptable when a T score treatment threshold of <-2.5 was used. These conclusions are limited by the lack of data on fracture and treatment efficacy in corticosteroid-treated patients.
A stochastic model of organizational mortality: Review and reanalysis☆

Abstract An effort is made to integrate the research literatures of business policy and organizational sociology as they concern organizational mortality. The previous empirical studies of organizational mortality are reviewed and considered in light of current theoretical arguments. Three stochastic models are developed to test hypotheses concerning organizational mortality: the constant rate model, the Gompertz model, and Makeham's Law. The parameters of these models are estimated for 52 sets of data on organizational mortality. The findings show that Makeham's Law is the best-fitting model, although its estimation requires data with low levels of censoring. Substantively, the findings show strong support for Stinchombe's liability-of-newness hypothesis [ A. L. Stinchcombe (1965) , “Organizations and social structure,” in Handbook of Organizations (J. G. March, Ed.), pp. 153–193, Rand McNally, Chicago].
α2-MACROGLOBULIN AND REDUCED BASEMENT-MEMBRANE DEGRADATION IN DIABETES

Thickening of the capillary basement membrane is the fundamental morphological alteration of diabetic microangiopathy. Leucocyte neutral proteases can degrade basement membrane in vivo. The activity of a purified neutral protease from granulocytes is inhibited by alpha2-macroglobulin. It is suggested that the reported increase in the concentration of alpha 2-macroglobulin in the blood of diabetic patients inhibits the activity of leucocyte neutral proteases which normally degrade basement membrane. The resultant decreased rate of breakdown would contribute to the increase in basement-membrane material seen in diabetes.
Scanning Alanine Mutagenesis and De-peptidization of a Candida albicans Myristoyl-CoA:ProteinN-Myristoyltransferase Octapeptide Substrate Reveals Three Elements Critical for Molecular Recognition

Candida albicans produces a single myristoyl-CoA:protein N-myristoyltransferase (Nmt) that is essential for its viability. An ADP-ribosylation factor (Arf) is included among the few cellular protein substrates of this enzyme. An octapeptide (GLYASKLS-NH2) derived from a N-terminal Arf sequence was used as the starting point to identify elements critical for recognition by the acyltransferases's peptide-binding site. In vitro kinetic studies, employing purified Nmt and a panel of peptides with single Ala substitutions at each position of GLYASKLS-NH2, established that its Gly1, Ser5, and Lys6 residues play predominant roles in binding. ALYASKLS-NH2 was found to be an inhibitor competitive for peptide (Ki = 15.3 +/- 6.4 microM) and noncompetitive for myristoyl-CoA (Ki = 31.2 +/- 0.7 microM). A survey of 26 derivatives of this inhibitor, representing (i) a complete alanine scan, (ii) progressive C-terminal truncations, and (iii) manipulation of the physical-chemical properties of its residues 1, 5, and 6, confirmed the important stereochemical requirements for the N-terminal amine, the beta-hydroxyl of Ser5, and the epsilon-amino group of Lys6. Remarkably, replacement of the the N-terminal tetrapeptide of ALYASKLS-NH2 with an 11-aminoundecanoyl group produced a competitive inhibitor, 11-aminoundecanoyl-SKLS-NH2, that was 38-fold more potent (Ki = 0.40 +/- 0.03 microM) than the starting octapeptide. Removing the primary amine (undecanoyl-SKLS-NH2), or replacing it with a methyl group (dodecanoyl-SKLS-NH2), resulted in 26- and 34-fold increases in IC50, confirming the important contribution of the amine to recognition. Removal of LeuSer from the C terminus (11-aminoundecanoyl-SK-NH2) yielded a competitive dipeptide inhibitor with a Ki (11.7 +/- 0.4 microM) equivalent to that of the starting octapeptide, ALYASKLS-NH2. Substitution of Ser with homoserine, cis-4-hydroxyproline, or tyrosine reduces potency by 3-70-fold, emphasizing the requirement for proper presentation of the hydroxyl group in the dipeptide inhibitor. Substituting D- for L-Lys decreases its inhibitory activity >100-fold, while deletion of the epsilon-amino group (Nle) or masking its charge (epsilon-N-acetyl-lysine) produces 4-7-fold attenuations. L-His, but not its D-isomer, can fully substitute for L-Lys, producing a competitive dipeptide inhibitor with similar potency (Ki = 11.9 +/- 1.0 microM). 11-Aminoundecanoyl-SK-NH2 and 11-aminoundecanoyl-SH-NH2 establish that a simple alkyl backbone can maintain an appropriate distance between three elements critical for recognition by the fungal enzyme's peptide-binding site: a simple omega-terminal amino group, a beta-hydroxyl, and an epsilon-amino group or an imidazole. These compounds contain one peptide bond and two chiral centers, suggesting that it may be feasible to incorporate these elements of recognition, or functionally equivalent mimics, into a fully de-peptidized Nmt inhibitor.
Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice

SARS coronavirus (SARS-CoV) encodes several unique group-specific open reading frames (ORFs) relative to other known coronaviruses. To determine the significance of the SARS-CoV group-specific ORFs in virus replication in vitro and in mice, we systematically deleted five of the eight group-specific ORFs, ORF3a, OF3b, ORF6, ORF7a, and ORF7b, and characterized recombinant virus replication and gene expression in vitro. Deletion of the group-specific ORFs of SARS-CoV, either alone or in various combinations, did not dramatically influence replication efficiency in cell culture or in the levels of viral RNA synthesis. The greatest reduction in virus growth was noted following ORF3a deletion. SARS-CoV spike (S) glycoprotein does not encode a rough endoplasmic reticulum (rER)/Golgi retention signal, and it has been suggested that ORF3a interacts with and targets S glycoprotein retention in the rER/Golgi apparatus. Deletion of ORF3a did not alter subcellular localization of the S glycoprotein from distinct punctuate localization in the rER/Golgi apparatus. These data suggest that ORF3a plays little role in the targeting of S localization in the rER/Golgi apparatus. In addition, insertion of the 29-bp deletion fusing ORF8a/b into the single ORF8, noted in early-stage SARS-CoV human and civet cat isolates, had little if any impact on in vitro growth or RNA synthesis. All recombinant viruses replicated to wild-type levels in the murine model, suggesting that either the group-specific ORFs play little role in in vivo replication efficiency or that the mouse model is not of sufficient quality for discerning the role of the group-specific ORFs in disease origin and development.
Circumferential type A aortic dissection and intimal intussusception of the aorta causing severe aortic regurgitation and obstruction of the left main coronary artery.

Author(s): Yang, Eric H; Kwon, Murray H; Mahajan, Aman; Child, John S; Tobis, Jonathan M; Manthripragada, Gopi; Silverstein, Cheri A; Shamsa, Kamran
Fuelwood Consumption and Deforestation in the Philippines

1992 The Paths to Domination, Resistance and Terror. Berkeley: University of California Press. Parker, Karen 1989 The Rights of Refugees Under International Humanitarian Law. In Refugee Law and Policy. V.P. Nanda, ed. Pp. 33-42. New York: Greenwood Press. Pike, Mary Boresz 1993 "Terrorism" and the Political Offense Exception. Paper Presented at the 2d Biennial International Criminal Law Seminar, Madrid, Spain. Renteln. Allison 1990 International Human Rights: Universalism Versus Relativism. Newbury Park: Sage Publications. Scott, James C. 1990 Domination and the Arts of Resistance. New Haven: Yale University Press. Sluka, Jeffrey 1990 Participant-Observation in Violent Social Contexts. Human Organization 49(2): 114-205. United Nations Economic and Social Council 1995 Question of the Human Rights of All Persons Subjected to Any Form of Detention or Imprisonment, in Particular: Torture and Other Cruel, Inhuman or Degrading Treatment or Punishment. Report of the Special Rapporteur Mr. Nigel S. Rodley to the Commission on Human Rights Fiftieth Session. New York United Nations. Washburn, Wilcomb 1987 Cultural Relativism, Human Rights, and the AAA. American Anthropologist 89:939-943. Wilson, Heather A. 1988 International Law and the Use of Force by National Liberation Movements. Clarendon: Oxford University Press. Wolpert, Stanley 1993 ANew History of India,4th ed. New York: Oxford Univ. Press.
Least squares fit of data to hyperbolic dose-response curves using a programmed minicalculator (TI-59)

Abstract Equations of the Michaelis-Menten form are frequently encountered in a number of areas of biochemical and pharmacological research. A program is presented for use on the programmable TI-59 calculator with added printer which performs an interative least-squares fit of up to 80 data pairs to this equation and estimates the standard deviations and standard errors of the determined parameters. The program assigns equal weights to errors over the entire data range and is thus appropriate for situations in which data precision is independent of amplitude.
A pattern recognition account of decision making

In the domain of pattern recognition, experiments have shown that perceivers integrate multiple sources of information in an optimal manner. In contrast, other research has been interpreted to mean that decision making is nonoptimal. As an example, Tversky and Kahneman (1983) have shown that subjects commit a conjunction fallacy because they judge it more likely that a fictitious person named Linda is a bank teller and a feminist than just a bank teller. This judgment supposedly violates probability theory, because the probability of two events can never be greater than the probability of either event alone. The present research tests the hypothesis that subjects interpret this judgment task as a pattern recognition task. If this hypothesis is correct, subjects’ judgments should be described accurately by the fuzzy logical model of perception (FLMP)—a successful model of pattern recognition. In the first experiment, the Linda task was extended to an expanded factorial design with five vocations and five avocations. The probability ratings were described well by the FLMP and described poorly by a simple probability model. The second experiment included (1) two fictitious people, Linda and Joan, as response alternatives and (2) both ratings and categorization judgments. Although the ratings were accurately described by both the FLMP and an averaging of the sources of information, the categorization judgments were described better by the FLMP. These results reveal important similarities in recognizing patterns and in decision making. Given that the FLMP is an optimal method for combining multiple sources of information, the probability judgments appear to be optimal in the same manner as pattern-recognition judgments.
CAFE compliance by light trucks: economic impacts of clean diesel engine

Abstract With the popularity of light trucks increasing in the United States, their share of the US light vehicle market had doubled between 1980 and 1996, climbing from 20 to 40%. By 1996, annual energy consumption for light trucks had risen to 5.97×1015 Btu [5.97 quadrillion Btu, or “quad,” or 6.30×1018 joule (J)], compared to 7.94 quad (8.38×1018 J) for cars. In recent years (since 1995), the fuel economy of US - manufactured light trucks (almost 99% of which use gasoline engines) has been below the Corporate Average Fuel Economy (CAFE) standards. This paper analyzes a strategy to reduce the CAFE shortfalls by adopting the new, highly energy-efficient clean diesel engine. Research on such engines has been funded by the US Department of Energy, Office of Heavy Vehicle Technologies, under its Light Truck Clean Diesel Engine Program. A clean diesel engine market penetration trajectory is developed, representing an industry response to meet the CAFE standards. Whether the engine will be produced inside the country or imported remains uncertain, so two cases are defined. Values of exports/imports of clean diesel engines/trucks under these cases are estimated. The macroeconomic benefits are estimated by using a model of the US economy developed by Standard & Poor's Data Resources, Inc. On the basis of gains in the gross domestic product projected under the alternative cases, domestic production of the clean diesel engine is favored over importing it.
Safety and Efficacy of the Gunther Tulip Retrievable Vena Cava Filter: Midterm Outcomes

To evaluate of the medium-term integrity, efficacy, and complication rate associated with the Gunther Tulip vena cava filter. A retrospective study was performed of 369 consecutive patients who had infrarenal Gunther Tulip inferior vena cava filters placed over a 5-year period. The mean patient age was 61.8 years, and 59 % were men. Venous thromboembolic disease and a contraindication to or complication of anticoagulation were the indications for filter placement in 86 % of patients; 14 % were placed for prophylaxis in patients with a mean of 2.3 risk factors. Follow-up was obtained by review of medical and radiologic records. Mean clinical follow-up was 780 days. New or recurrent pulmonary embolus occurred in 12 patients (3.3 %). New or recurrent deep-vein thrombosis occurred in 53 patients (14.4 %). There were no symptomatic fractures, migrations, or caval perforations. Imaging follow-up in 287 patients (77.8 %) at a mean of 731 days revealed a single (0.3 %) asymptomatic fracture, migration greater than 2 cm in 36 patients (12.5 %), and no case of embolization. Of 122 patients with CT scans, asymptomatic perforations were identified in 53 patients (43.4 %) at a mean 757 days. The Gunther Tulip filter was safe and effective at 2-year follow-up. Complication rates were similar to those reported for permanent inferior vena cava filters.
Posterior cerebral artery stenosis

We analyzed the clinical features of symptomatic posterior cerebral artery (PCA) stenosis in 6 patients selected from 15 patients with angiographically documented PCA atherostenosis occurring during a 7-year period. Transient ischemic attacks (TIAs) were the major presentation in 5 patients. A homonymous visual field defect was present in 2 patients. TIA symptoms were predominantly visual or sensory, or both. The most common visual symptom was difficulty seeing to one side. One patient saw flashing lights. Sensory spells were always paresthetic, usually involving the arm and hand and occasionally the face and leg. Three patients had visual and sensory spells together. Two patients with a visual field defect had calcarine infarcts found by computed tomography. All patients were treated with warfarin. During follow-up (4 months to 4 years), no patient had a new stroke in the PCA territory, and only one continued to have TIAs. PCA atherostenosis is rarer then PCA embolic occlusion. In contrast to those with PCA embolism, our patients with PCA atherostenosis had more TIAs and fewer infarcts. The clinical features of PCA stenosis--preponderance of visual and sensory TIAs--distinguish this vascular lesion from stenosis of the middle cerebral artery.
Bladder wall thickness and ultrasound estimated bladder weight in healthy adults with portative ultrasound device

Background: The aim of this study was to investigate bladder wall thickness (BWT) and ultrasound estimated bladder weight (UEBW) values in healthy population with a portative ultrasound device and their relationship with demographic parameters. Materials and Methods: The study was carried out in Neurorehabilitation Clinic of Ege University Hospital. Ninety‑five subjects (48 women and 47 men) aged between 18 and 56 were included in the study. BWT and UEBW were determined non‑invasively with a portative ultrasound device; Bladder Scan BVM 6500 (Verathon Inc., WA, USA) at a frequency of 3.7 MHz at functional bladder capacity. These values were compared by gender, and their relation was assessed with age, body mass index (BMI) and parity. Results: Mean BWT was 2.0 ± 0.4 mm and UEBW was 44.6 ± 8.3 g at a mean volume of 338.0 ± 82.1 ml. Although higher results were obtained in men at higher bladder volumes, the results did not differ significantly by gender. Correlation analyses revealed statistically significant correlation between UEBW and age ( r = 0.32). BWT was negatively correlated with volume (r = –0.50) and bladder surface area (r = –0.57). Also, statistically significant correlations were observed between UEBW and volume ( r = 0.36), bladder surface area (r = 0.48) and BWT (r = 0.25). Conclusion: Determined values of BWT and UEBW in healthy population are estimated with portative ultrasound devices, which are future promising, for their convenient, easy, non‑invasive, time‑efficient hand‑held use for screening.
A cluster analytic approach to interest measurement with the ACT Interest Inventory

ix INTRODUCTION 1 Career choice 1 Vocational Interests 2 Vocational Taxonomy 3 Career Development 4 Overview of this Study 5 LITERATURE REVIEW 7 Classification 7 Early Approaches 7 Statistical Approaches to Classification 7 Goals of Taxonomic Classification 7 Cluster analysis 8 Use of Cluster Analysis 10 Methods of Cluster Analysis 11 Ward's Method 12 Linkage Methods 13 N onhierarchical Methods 15 Which Method Should be Used? 15 Procedures for Clustering 18 Meaningfulness of a Cluster Solution 20 Reporting Clustering Research 21 Cluster Analysis in the Psychological Arena 21 Cluster Analysis and Vocational Data 27 Clustering on Interest and Career Inventories 28 Gender and Interest Measurement 32 Career Choice: Other Important Variables 33 Limitations of Theory and Research 35
An Empirical Study of Function Overloading in C

The usefulness and usability of programming tools (for example, languages, libraries, and frameworks) may greatly impact programmer productivity and software quality. Ideally, these tools should be designed to be both useful and usable.But in reality, there always exist some tools or features whose essential characteristics can be fully understood only after they have been extensively used. The study described in this paper is focused on discovering how C++'s function overloading is used in production code using an instrumented g++ compiler. Our principal finding for the system studied is that the most 'advanced' subset of function overloading tends to be defined in only a few utility modules, which are probably developed and maintained by a small number of programmers, the majority of application modules use only the 'easy' subset of function overloading when overloading names,and most overloaded names are used locally within rather than across module interfaces.We recommend these as guidelines to software designers.
Spitzer Observations of a 24 μm Shadow: Bok Globule CB 190*

We present Spitzer observations of the dark globule CB 190 (LDN 771). We observe a roughly circular 24 μm shadow with a 70'' radius. The extinction profile of this shadow matches the profile derived from 2MASS photometry at the outer edges of the globule and reaches a maximum of ~32 visual magnitudes at the center. The corresponding mass of CB 190 is ~10 M☉. Our 12CO and 13CO J = 2-1 data over a 10' × 10' region centered on the shadow show a temperature ~10 K. The thermal continuum indicates a similar temperature for the dust. The molecular data also show evidence of freezeout onto dust grains. We estimate a distance to CB 190 of 400 pc using the spectroscopic parallax of a star associated with the globule. Bonnor-Ebert fits to the density profile, in conjunction with this distance, yield ξmax = 7.2, indicating that CB 190 may be unstable. The high temperature (56 K) of the best-fit Bonnor-Ebert model is in contradiction with the CO and thermal continuum data, leading to the conclusion that the thermal pressure is not enough to prevent free-fall collapse. We also find that the turbulence in the cloud is inadequate to support it. However, the cloud may be supported by the magnetic field, if this field is at the average level for dark globules. Since the magnetic field will eventually leak out through ambipolar diffusion, it is likely that CB 190 is collapsing or in a late precollapse stage.
Doing Consciousness Studies at Goddard College

In the first part of this article we briefly describe the design and development of a Consciousness Studies concentration at Goddard College, a student centered, progressive educational institution in the northeastern United States. We emphasize the tensions we experienced between different orientations in Consciousness Studies and especially the one related to the scientific and transpersonal ends of the spectrum of consciousness. In the second part, we relate the scientific-transpersonal issue that we experienced at Goddard to the broader theory and practice of Consciousness Studies. We also link the latter to the so-called explanatory gap between third and first person forms of consciousness and the call for first person methods of exploring consciousness. Our conclusion is that the scientific approach has the edge and is at risk of assimilating other approaches to the detriment of Consciousness Studies. In our view, the future development of Consciousness Studies, both in theory and practice, requires several different approaches from the scientific to the transpersonal and privileging one is to narrow the field of possibilities and to risk falling prey to one-sidedness.
Role of l-Arginine in the Pathogenesis and Treatment of Renal Disease

L-arginine is a semi essential amino acid and also a substrate for the synthesis of nitric oxide (NO), polyamines, and agmatine. These L-arginine metabolites may participate in the pathogenesis of renal disease and constitute the rationale for manipulating L-arginine metabolism as a strategy to ameliorate kidney disease. Modification of dietary L-arginine intake in experimental models of kidney diseases has been shown to have both beneficial as well as deleterious effects depending on the specific model studied. L-arginine supplementation in animal models of glomerulonephritis has been shown to be detrimental, probably by increasing the production of NO from increased local expression of inducible NO synthase (iNOS). L-arginine supplementation does not modify the course of renal disease in humans with chronic glomerular diseases. However, beneficial effects of L-arginine supplementation have been reported in several models of chronic kidney disease including renal ablation, ureteral obstruction, nephropathy secondary to diabetes, and salt-sensitive hypertension. L-arginine is reduced in preeclampsia and recent experimental studies indicate that L-arginine supplementation may be beneficial in attenuating the symptoms of preeclampsia. Administration of exogenous L-arginine has been shown to be protective in ischemic acute renal failure. In summary, the role of L-arginine in the pathogenesis and treatment of renal disease is not completely understood and remains to be established.
Integrable open spin chains and the doubling trick in Script N = 2 SYM with fundamental matter

We demonstrate that the one-loop anomalous dimension matrix in = 2 SYM with a single chiral hypermultiplet of fundamental matter, which is dual to AdS5 × S5 with a D7-brane filling AdS5 and wrapped around an S3 in the S5, is an integrable open spin chain Hamiltonian. We also use the doubling trick to relate these open spin chains to closed spin chains in pure = 4 SYM. By using the AdS/CFT correspondence, we find a relation between the corresponding open and closed strings that differs from a simple doubling trick by terms that vanish in the semiclassical limit. We also demonstrate that in some cases the closed string is simpler and easier to study than the corresponding open string, and we speculate on the nature of corrections due to the presence of D-branes that this implies.
Enforcing the Human Rights of Citizens and Non‐Citizens in the Era of Maastricht: Some Reflections on the Importance of States

This article explores the impact of globalization in the context of human rights enforcement within the European Union. It argues that despite the growing impact of transnational forces and supranational institutions, national mechanisms are still crucial in enforcing international obligations, so that states remain critical players rather than diminishing entities. The article considers the development of human rights as a fundamental norm within the European Union, and explores the relevance of this norm for third country (i.e. non-European) nationals. It argues that restrictionist policies designed to curtail immigration and exclude asylum seekers override international human rights obligations voluntarily entered into by the European member states. Even the concept of European Union citizenship, designed in part to address the rights deficit within Europe, has not so far created a base of fundamental rights capable of trumping state interests, but rather functions primarily as an exclusionary concept directed against non-Europeans.
Invertibility of higher order moment matrices

Signal processing algorithms based on Volterra filter structures often require that a matrix composed of higher order moments of the underlying process be invertible. Previously, this problem has been studied for uncorrelated random variables. The paper establishes conditions under which a wide class of correlated processes have invertible higher order moment matrices. >
In vitro analysis of sequence requirements for the excision reaction of the Bacteroides conjugative transposon, CTnDOT.

Summary CTnDOT, a Bacteroides conjugative transposon (CTn), initiates its transfer by excising to form a circular intermediate. This process has been shown to be complex, involving an unusual DNA intermediate with a short region of heterology and several CTn-encoded proteins. No information was available, however, about the sizes or sequence requirements of the att sites (attL and attR) at the ends of the integrated element where the processing occurs during excision. Using a newly developed in vitro competition excision assay, we have now localized attL to 153 bp and attR to 179 bp. Excision of CTnDOT involves staggered cuts that produce 5 bp chromosomal sequences at either end of the CTn. These 5 bp sequences (coupling sequences) form a region of heterology in the excised circular intermediate. Site-directed mutations that made the coupling sequences complementary and removed the region of heterology had no effect on excision. Thus, heterology is not essential. Mutagenesis of sequences adjacent to the coupling sequences revealed a 6 bp site in attR that was essential for excision. Mutating the analogous region in attL had little effect on excision. Regions within the attL site that appear to play a role in excision were found by introducing small insertions (phasing mutations) that could interfere with protein–protein or protein–DNA interactions. Similar insertion mutations in attR had no significant effect on excision. These results support the hypothesis that the CTnDOT excision reaction is asymmetrical with respect to likely protein binding sites and involves multiple protein–DNA interactions.
Protistan Predation Affects Trichloroethene Biodegradation in a Bedrock Aquifer

Despite extensive research on the bottom-up force of resource availability (e.g., electron donors and acceptors), slow biodegradation rates and stalling at cis-dichloroethene (cDCE) and vinyl chloride continue to be observed in aquifers contaminated with trichloroethene (TCE). The objective of this research was to gauge the impact of the top-down force of protistan predation on TCE biodegradation in laboratory microcosms. When indigenous bacteria from an electron donor-limited TCE-contaminated bedrock aquifer were present, the indigenous protists inhibited reductive dechlorination altogether. The presence of protists during organic carbon-amended conditions caused the bacteria to elongate (length:width, ≥10:1), but reductive dechlorination was still inhibited. When a commercially available dechlorinating bacterial culture and an organic carbon amendment were added in he presence of protists, the elongated bacteria predominated and reductive dechlorination stalled at cDCE. When protists were removed under organic carbon-amended conditions, reductive dechlorination stalled at cDCE, whereas in the presence organic carbon and bacterial amendments, the total chlorinated ethene concentration decreased, indicating TCE was converted to ethene and/or CO2. The data suggested that indigenous protists grazed dechlorinators to extremely low levels, inhibiting dechlorination altogether. Hence, in situ bioremediation/bioaugmentation may not be successful in mineralizing TCE unless the top-down force of protistan predation is inhibited.
Excretion of anti-angiogenic proteins in patients with chronic allograft dysfunction

Background. We have recently documented the appearance of an anti-angiogenic peptide, endorepellin, in the urine of patients with chronic allograft dysfunction (CAD). Methods. Here, we analyzed, using enzyme-linked immunosorbent assay, the excretion of anti-angiogenic peptides endostatin, pigment epithelium-derived factor (PEDF) and Kruppel-like factor-2 (KLF-2), in healthy individuals, patients with stable graft function and patients with various degrees of CAD. Results. In healthy subjects and patients with CAD-0, endostatin, PEDF and KLF-2 excretions were at the level of detection. In contrast, there were significant differences between the patients with CAD-3 and CAD-0, CAD-1 and healthy controls for endostatin and CAD-0 versus CAD-3 for PEDF, but no differences in KLF-2 excretion. Receiver operating characteristic (ROC) curve analyses demonstrated a highly discriminative profile for all three biomarkers: the combination of these parameters offered 83% sensitivity and 90% specificity in distinguishing CAD-0 from CAD-1–3. The quality of these potential biomarkers of CAD was, however, highest in discriminating CAD status in biopsy-proven cases and dropped when CAD-0 was diagnosed based on clinical criteria. Conclusions. In conclusion, these findings indicate the diagnostic potential of urinary detection of endostatin, PEDF and to lesser degree KLF-2 and suggest a mechanistic role played by anti-angiogenic substances in the developing vasculopathy and vascular rarefaction in patients with CAD.
Voltage over-scaling: A cross-layer design perspective for energy efficient systems

Today's multi-media electronic era is driven by the increasing demand for small multifunctional devices able to support diverse services. Unfortunately, the high levels of transistor integration and performance required by such devices lead to an unprecedented increase of on-chip power that significantly limits the battery lifetime and even poses reliability concerns. Several techniques have been developed to address the power increase, but voltage over-scaling (VOS) is considered to be one of the most effective ones due to the quadratic dependence of voltage on dynamic power consumption. However, VOS may not always be applicable since it increases the delay in all paths of a system and may limit high performance required by today's complex applications. In addition, application of VOS is further complicated since it increases the variations in transistor characteristics imposed by their tiny size which can lead to large delay and leakage variations, making it difficult to meet delay and power budgets. This paper presents a review of various cross-layer design options that can provide solutions for dynamic voltage over-scaling and can potentially assist in meeting the strict power budgets and yield/quality requirements of future systems.
Engineering over-clocking: reliability-performance trade-offs for high-performance register files

Register files are in the critical path of most high-performance processors and their latency is one of the most important factors that limit their size. Our goal is to develop error correction mechanisms at the architecture level. Utilizing this increased robustness, the clock frequencies of the circuits are pushed beyond the point of allowing full voltage swing. This increases the errors observed due to noise and other external factors. The resulting errors are then corrected through the error correction mechanisms. We first develop a realistic model for error probability in register files for a given clock frequency. Then, we present the overall architecture, which allows the error detection computation to be overlapped with other computation in the pipeline. We develop novel techniques that utilize the fact that at a given instance many physical registers are not used in superscalar processors. These underutilized registers are used to store the values of active registers. Our simulation results show that for a fixed architecture the access times to the registers can be reduced by as much as 80% while increasing the number of execution cycles by 0.12%. On the other hand, by reducing the register file access pipeline stages by 75%, the average number of execution cycles of SPEC applications can be reduced by 11.5%.