cssi/SciSciGPT-SciSciNet huggingface dataset:
Therapist Attitudes Towards Computer-Based Trainings

Computer-based trainings are a promising avenue for increasing access to training in evidence-based practices. However, little is known about whether therapists are willing to use them. Results from a national survey of practicing therapists (N = 1,067) indicated that 26 % of therapists reported previously using a computer-based training and overall attitudes (as measured by the Computer-Based Training Attitudes Scale) were positive. Higher therapist computer fluency and greater openness to new treatments predicted positive attitudes. Therapists with more positive attitudes were more likely to have previously used a computer-based training. Implications are discussed.
Beyond The Bridge on the River Kwai : Labor Mobilization in the Greater East Asia Co-prosperity Sphere

Japan's war in Asia and the Pacific would have ground to a halt long before 1945 without the labor of millions of foreign workers, most of them mobilized against their will. For example, production of coal (then Japan's primary energy source) depended in large part on coerced labor from Korea, a Japanese colony from 1910 to 1945. Throughout Japan's wartime empire, at least fifteen million Asians were put to work, often under brutally exploitative conditions, constructing roads, bridges, and air fields; digging minerals; and building boats, among many other projects. Untold thousands died because of harsh treatment, inadequate food and medical care, and poor planning. Many surviving workers, some of whom were left permanently disabled, are still waiting today for the wages they were promised. Such a large, destructive enterprise naturally had consequences that outlived the war. Coercive labor mobilization tore families and communities apart and sharpened class resentments, contributing to revolutionary upheavals after August 1945 in Korea and Indonesia, for example. In Japan itself, where mobilization took place on a relatively small scale and with comparatively little coercion, it left a complex, contradictory legacy, invigorating the labor movement in some ways and strengthening the hand of capital in others. Unlike the situation in Germany, where corporations have recently agreed to compensate wartime forced workers, both the state and corporations in Japan have refused to consider compensation for the foreign workers who kept Japan's war machine running from 1939 to 1945.
Necrotizing Fasciitis as the Clinical Presentation of a Retroperitoneal Abscess

Infections of the retroperitoneal space may present with insidiously vague symptoms and non-specific clinical signs. We report a case of a retroperitoneal abscess presenting as necrotizing fasciitis of the thigh from direct spread over the iliac crest. In cases of necrotizing fasciitis of the thigh with no obvious source, an intra-abdominal nidus of infection may be considered.
Antibiotic Prophylaxis in Cancer Patients: Regimens of Oral, Nonabsorbable Antibiotics for Prevention of Infection During Induction of Remission

The high frequency of complications caused by infections during therapy of malignant diseases has led to the development of prophylactic programs. The most effective prophylaxis has included the use of protected environments and antibiotic regimens (PEPA). Most oral prophylactic regimens include vancomycin to provide coverage against aerobic, gram-positive cocci and some anaerobes. Regimens of nonabsorbable antibiotics are effective in eliminating the vast majority of bacteria from the stool, but the antifungal agents are less effective. However, once the antibiotic regimen is discontinued, organisms previously cultured will reappear. Several prospective, randomized studies have been conducted of patients with acute leukemia who are undergoing chemotherapy administered to induce remission. The frequency of complications caused by infection has been significantly lower for patients in the PEPA program than for controls. A recent study of patients with lymphoma has shown that patients in the PEPA program can tolerate higher doses of chemotherapy than can control patients and that they have lower frequency of complications caused by infection.
Gender-Typed Play Behavior in Early Childhood: Adopted Children with Lesbian, Gay, and Heterosexual Parents

This study examined whether the gender-typed play of young children varies as a function of family structure. Using a sample of 126 couples (44 lesbian couples, 34 gay male couples, and 48 heterosexual couples) located throughout the United States, with an adopted child between the age of 2 and 4 years old (mean = 2.5 years), we examined parent reports of children’s gender-typed play behavior utilizing the Pre-School Activities Inventory (PSAI; Golombok and Rust 1993). Findings revealed that the perceived play behaviors of boys and girls in same-gender parent families were more similar (i.e., less gender-stereotyped) than the perceived play behavior of boys and girls in heterosexual-parent families (which were more divergent; that is, gender-stereotyped). Sons of lesbian mothers were less masculine in their play behavior than sons of gay fathers and sons of heterosexual parents. Our findings have implications for researchers who study gender development in children and adolescents.
Decontamination of Nasal Atomizer Tips Alcohol versus Guards

Objective. To determine the efficacy of wiping the nasal atomizer tip with 70% isopropanol versus using single-use plastic atomizer tip guards in preventing cross-contamination.Study Design. Single...
Failure mechanisms and electromechanical coupling in semiconducting nanowires

One dimensional nanostructures, like nanowires and nanotubes, are increasingly being researched for the development o f next generation devices like logic gates, transistors, and solar cells. In particular, semiconducting nanowires with a non- symmetric wurtzitic crystal structure, such as zinc oxide (ZnO) and gallium nitride (GaN), have drawn immense research interests due to their electromechanical coupling. The designing of the future nanowire-based devices requires component-level characterization of individual nanowires. In this p aper, we present a unique experimental set-up to characterize the mechanical and electrome chanical behaviour of individual nanowires. Using this set-up and complementary atomistic simulations, mechanical properties of ZnO nanowires and electromechanical properties of GaN nanowires were investigated. In ZnO nanowires, elastic modulus was found to depend on nanowire diameter decreasing from 190 GPa to 140 GPa as the wire diameter increased from 5 nm to 80 nm. Inconsistent failure mechanisms were observed in ZnO nanowires. Experiments revealed a brittle fracture, whereas si mulations using a pairwise potential predicted a phase transformation prior to failure. This inconsistency is addressed in detail from an experimental as well as computationa l perspective. Lastly, in addition to mechanical properties, preliminary results on the e lectromechanical properties of gallium nitride nanowires are also reported. Initia l investigations reveal that the piezoresistive and piezoelectric behaviour of nanow ires is different from bulk gallium nitride.
A NHERF binding site links the betaPDGFR to the cytoskeleton and regulates cell spreading and migration.

The Na + /H + exchanger regulatory factor, NHERF, is a multifunctional adapter protein involved in a wide range of physiological activities. NHERF associates with merlin and the ezrin/radixin/moesin (MERM) family of membrane-actin cytoskeletal linker proteins through its C-terminus and is capable of interacting via its PDZ1 domain to the βPDGF receptor (βPDGFR). Thus, NHERF, potentially links the βPDGFR to the actin cytoskeleton through its interaction with MERM proteins. In the present study, we have examined whether abolishing the interaction of βPDGFR with NHERF results in actin cytoskeletal rearrangements. We have stably expressed a wild-type βPDGFR, a mutant βPDGFR (L1106A) that is incapable of interacting with NHERF, as well as a kinase defective mutant receptor (K634R), in PDGFR-deficient mouse embryonic fibroblasts. Our observations indicate that cells expressing βPDGFR (L1106A) were impaired in their ability to spread and migrate on fibronectin compared with wild-type and K634R cells. L1106A mutant cells also revealed an increased number of focal adhesions, a condensed F-actin ring at the cell periphery and a decrease in total focal adhesion kinase (FAK) tyrosine phosphorylation. Further, we show that NHERF and MERM proteins could act as intermediary bridging proteins between βPDGFR and FAK. Thus, the interaction of βPDGFR with NHERF may provide an essential link between the cell membrane and the cortical actin cytoskeleton independent of receptor activity.
Blind convolution using signal reconstruction from partial higher order cepstral information

A blind deconvolution scheme for the reconstruction of a signal that propagates in the presence of reverberation and additive noise is presented. The reconstruction employs data collected by two receivers placed well apart from each other. Each received sequence consists of the convolution of the transmitted signal with a channel. Applying the bicepstrum iterative reconstruction algorithm on the differences of the cepstra coefficients of the two received sequences, the cepstra coefficients of the transmission channels can be computed and used for the reconstruction of the transmitted signal. The deconvolution can be performed even if the data sequences are corrupted by additive noise. The computation of the cepstra coefficients is based on the cross-bispectrum if the noise processes present in the observation sequences are zero mean and uncorrelated, while the bicepstrum of each observation is used if the noise processes are zero mean correlated with a symmetric probability density function. >
A multidisciplinary model of care for childhood cancer survivors with complex medical needs.

Long-term survival for children with cancer is often achieved at a considerable cost in terms of medical and psychological sequelae. Although many survivors are well and require only routine follow-up and surveillance, a cohort of survivors require comprehensive management of complex, chronic medical issues by multiple subspecialists. For these survivors, care delivered within the context of an annual visit to a traditional hospital—based late effects clinic or by a primary care physician in the community is often not adequate. A specialized clinic was implemented at The Children's Hospital of Philadelphia that crosses disciplines and provides same-day, same-clinic access to oncology/survivorship, endocrinology, pulmonology, cardiology, nutrition, and psychology. This multidisciplinary approach supports clinical efficiency and fosters seamless patient-centered care both for patients with identified late effects and for those with the highest risk for problems because of intense treatment exposures. The mo...
Projection Image of Smooth Muscle α-Actinin from Two-dimensional Crystals Formed on Positively Charged Lipid Layers

Two-dimensional crystalline arrays of chicken gizzard α-actinin have been formed on positively charged lipid layers. This is the first reported crystallization of α-actinin. The crystals have unit cell dimensions of a = 248 A, b = 194 A, γ = 106° and contain two α-actinin molecules. The two-sided group is P21. Projection images obtained from electron micrographs of negatively stained crystals have been calculated to a resolution of 25 A. These images reveal a complex substructure. The molecule in projection is 340 A in length and has 12 density peaks that probably correspond to protein domains. A pair of peaks is found at each end of the molecule, these probably correspond to the actin binding region. Eight peaks are observed in the central, rod-shaped region, these may correspond to the spectrin-like repeats predicted from the amino acid sequence. However, these eight central peaks are not arranged in four pairs but, instead, consist of three central pairs flanked at either end by a single peak, which appears larger and denser in projection than the three central pairs. The individual α-actinin molecules in projection lack 2-fold symmetry suggesting that either smooth muscle α-actinin lacks a molecular 2-fold symmetry axis or that the molecular 2-fold is not parallel with the crystallographic 2-fold axis. The ends of the molecule have different appearance in projection, suggesting that the molecule is twisted about the long axis. A hypothesis is proposed to explain the variations in molecular length and Ca2+ sensitivity between α-actinin isoforms.
Management of Swirling Flows with Application to Wind Tunnel Design

The effect of various flow manipulators on different types of swirling flows was investigated experimentally in order to determine the important mechanisms involved and to gain insight into efficient means for removing such swirls from wind tunnels and duct flows. Several swirling test flow conditions were used which had different transverse distributions of angular momentum and turbulence intensity levels. They represented typical conditions arising in flows through ducts and wind tunnels. The effectiveness of commonly used flow manipulators, such as screens, grids, and honeycombs, in removing the swirl from these flows was established. Different mechanisms dominated depending upon the scaling between the swirl size and the characteristic lengths of the manipulator, with some mechanisms being more efficient in removing the swirl than others. In many cases, similar performance was obtained by any one of several manipulators, making it possible to select a flow manipulator based on other criteria, such as maximum turbulence suppression or minimum pressure drop, which are both very important in wind tunnel design and operation.
An architectural power estimator for analog-to-digital converters

This paper presents an architectural power estimation tool that can accurately estimate the power consumptions of analog-to-digital converters. Combining the advantages of both the bottom-up approach and the top-down approach, the estimator can help AMS SoC designer on high-level power optimized design without detailed knowledge of the circuit. The three-stage estimation process makes the estimator appropriate for architectural exploration of designs employing low power techniques. The framework makes it convenient to evaluate power dissipation of new customized architectures. Experimental results for 19 commercial designs show good estimation accuracy.
Gaussian process modeling for measurement and verification of building energy savings

Abstract We present a Gaussian process (GP) modeling framework to determine energy savings and uncertainty levels in measurement and verification (M&V) practices. Existing M&V guidelines provide savings calculation procedures based on linear regression techniques that are limited in their predictive and uncertainty estimation capabilities. We demonstrate that, unlike linear regression, GP models can capture complex nonlinear and multivariable interactions as well as multiresolution trends of energy behavior. In addition, because GP models are developed under a Bayesian setting, they can capture different sources of uncertainty in a more systematic way. We demonstrate that these capabilities can ultimately lead to significantly less expensive M&V practices. We illustrate the developments using simulated and real data settings.
3D maps from multiple MRI illustrate changing atrophy patterns as subjects progress from mild cognitive impairment to Alzheimer's disease

Mild cognitive impairment (MCI), particularly the amnestic subtype (aMCI), is considered as a transitional stage between normal aging and a diagnosis of clinically probable Alzheimer's disease (AD). The aMCI construct is particularly useful as it provides an opportunity to assess a clinical stage which in most subjects represents prodromal AD. The aim of this study was to assess the progression of cerebral atrophy over multiple serial MRI during the period from aMCI to progression to AD. Thirty-three subjects were selected that fulfilled clinical criteria for aMCI and had three serial MRI scans: the first scan ∼3 years before the diagnosis of AD, the second scan ∼1 year before, and the third scan at the time of the diagnosis of AD. A group of 33 healthy controls were age and gender-matched to the study cohort. Voxel-based morphometry (VBM) was used to assess patterns of grey matter atrophy in the aMCI subjects at each time-point compared to the control group. Customized templates and prior probability maps were used to avoid normalization and segmentation bias. The pattern of grey matter loss in the aMCI subject scans that were 3 years before the diagnosis of AD was focused primarily on the medial temporal lobes, including the amygdala, anterior hippocampus and entorhinal cortex, with some additional involvement of the fusiform gyrus, compared to controls. The extent and magnitude of the cerebral atrophy further progressed by the time the subjects were 1 year before the diagnosis of AD. At this point atrophy in the temporal lobes spread to include the middle temporal gyrus, and extended into more posterior regions of the temporal lobe to include the entire extent of the hippocampus. The parietal lobe also started to become involved. By the time the subjects had progressed to a clinical diagnosis of AD the pattern of grey matter atrophy had become still more widespread with more severe involvement of the medial temporal lobes and the temporoparietal association cortices and, for the first time, substantial involvement of the frontal lobes. This pattern of progression fits well with the Braak and Braak neurofibrillary pathological staging scheme in AD. It suggests that the earliest changes occur in the anterior medial temporal lobe and fusiform gyrus, and that these changes occur at least 3 years before progression to the diagnosis of AD. These results also suggest that 3D patterns of grey matter atrophy may help to predict the time to the first diagnosis of AD in subjects with aMCI.
Big-Bang Model Without Singularities

A uniform cosmological model filled with fluid which possesses pressure and second viscosity is developed. The Einstein equations can be integrated exactly. One solution is the steady-state cosmology, but this is unstable. Other solutions start from the steady-state one in the infinite past but expand more and more slowly as viscosity dies out. At any finite proper time in the past the curvature is finite. Some comments on possible origins of this viscosity are given.
Regulating the Timing of Disclosure: Insights from the Acceleration of 10-K Filing Deadlines

We study the effects of regulating the timing of disclosure on the quality of accounting information, using a 2003 U.S. regulatory change that accelerates 10-K filing deadlines as a research setting. Employing a difference-in-differences design, we find that the likelihood of issuing financial statements that are later restated increases for firms that are required to file more quickly, relative to firms whose filing practices are not affected by the regulatory change. This effect is particularly pronounced during the audit busy season, when auditors also face significant time pressure. These results are consistent with a tradeoff between how quickly accounting reports are required to be filed and the reliability of the resulting reports.
The social problem as an enterprise: Values as a defining factor

Ce texte, discours prononce a l'origine a New York en aout 1986 par le president de la SSSP, presentant l'etude des problemes sociaux comme une entreprise morale, n'avait jamais ete publie. Comment un sociologue engage dans ce type de travail identifie-t-il ce qui constitue un probleme social, et comment cerner les contours de la legitimite d'une activite d'amelioration sociale? Quelles valeurs pour guider une telle entreprise?
Polyurethanes. IV. Effect of poly(propylene glycol) tacticity on the properties of block copolyether‐urethanes

Block copolyether–urethane–ureas containing isotatic polypropylene glycols were synthesized and their dynamic mechanical properties compared to the analogous atactic structures. At poly(propylene glycol) molecular weights below 1000, tacticity appears to have little effect on the stress–strain properties of the block copolymers. At higher molecular weights, the ability of the isotatic polyglycol segments to crystallize under strain can effect cyclic deformation properties.
Hydrogen and methoxy coadsorption in the computation of the catalytic conversion of methanol on the ceria (111) surface

Abstract Methanol decomposition to formaldehyde catalyzed by the ceria (111) surface was investigated using the DFT + U method. Our results rationalize experimental temperature programmed desorption experiments on the fully oxidized surface. Particular attention was paid to the effect of coadsorption of methoxy and hydrogen on various aspects of the conversion process. This issue had been raised by the experimental observation of water desorption at low temperature removing hydrogen from the system. Within this context, we also investigated hydrogen diffusion on the ceria surface. The hydrogen/methoxy interaction on ceria was shown to be ionic regardless of separation distance. The barrier for dehydrogenation of methoxy using the ionic model system, where hydrogen is coadsorbed, is above 1 eV. This barrier becomes negligible if an incorrect neutral model without coadsorbed hydrogen is employed. While water formation from isolated surface hydrogen is unlikely at low temperature, the presence of coadsorbed methoxy reduces the reaction energy for water formation considerably. For the dehydrated surface, we observed that the preference of the electron to locate at the methoxy oxygen instead of the cerium atom results in a surface that does not contain Ce3 + ions, despite the existence of a vacancy.
Heeft de analoge afdruk nog toekomst

Vaak wordt aangenomen dat het maken van digitale afdrukken sneller gedaan is en patientvriendelijker is dan het nemen van een analoge afdruk. Wetenschappelijk bewijs is hier echter niet voor. In deze studie zijn de ervaringen van de patient en de benodigde tijdsduur onderzocht bij het maken van twee soorten afdrukken van de volledige boven- en onderkaak: een digitale en een analoge afdruk.
Abstract 131: Mitogen-Activated Protein Kinase Kinase Activation is Necessary for Macrophage Accumulation, Compensatory Growth of Blood Vessels and Muscle Regeneration Following Femoral Artery Ligation

Lower limb peripheral vascular disease (PVD) results from the occlusion of arteries leading to reduced blood flow and limb ischemia. Compensatory growth of blood vessels may be sufficient to overcome limb ischemia but for some patients therapeutic intervention, even limb amputation, is required. To gain insight into the mechanisms regulating compensatory growth of blood vessels we used a mouse model of hindlimb ischemia. The ischemic lesions were confirmed and compensatory arteriogenesis was evaluated by high frequency power Doppler ultrasound. In this model, compensatory growth occurs mainly through arteriogenesis. While signaling by mitogen activated protein kinase kinases 1 and 2 (MEK 1 and 2) is required for developmental and tumor angiogenesis, it is unknown whether MEK1/2 activity drives other physiologic vascular growth such as arteriogenesis. We hypothesized that MEK 1/2 activity is necessary for hindlimb re-vascularization following femoral artery ligation. To test this we ligated the femoral artery in mice and then treated them with PD0325901, an allosteric MEK1/2 inhibitor. Following femoral artery ligation active MEK signaling was detected in spindle-shaped cells located within regions of intense angiogenesis and myocyte proliferation. MEK inhibition with PD0325901 reversibly blocked neovascularization, muscle regeneration, and caused extensive coagulative necropathy. MEK inhibition not only prevented arteriogenesis in ischemic limbs but also caused a reduction in arterial diameter. Finally, MEK inhibition prevented accumulation of CD68+ cells in ischemic tissues and skewed systemic cytokine expression towards a persistent, pro-inflammatory phenotype. Our investigation provides pharmacologic evidence demonstrating an essential role for MEK signaling in angiogenesis and arteriogenesis in response to hind limb ischemia. Further, we observed activation of MEK signaling is required for accumulation of macrophages in ischemic tissues and prevents down-regulation of systemic pro-inflammatory cytokines. Lastly, since the effects of MEK inhibition on reperfusion are reversible, we can use MEK inhibitors to create a mouse model of chronic limb ischemia that mimics aspects of PVD.
The Effect of Triethylene Glycol Vapor on Air-Borne Beta Hemolytic Streptococci in Hospital Wards. II. The Combined Action of Glycol Vapor and Dust Control Measures.

In the preceding paper, a study of the effect of vaporizing triethylene glycol in hospital wards housing streptococcal carriers was reported. It was found that while a marked reduction in numbers of air-borne beta hemolytic streptococci could be produced, complete disappearance of these microorganisms from the air of the ward could rarely be achieved by this means.' Subsequent investigations and a further analysis of the mechanism of glycol action indicated that a large proportion of these streptococci originate from secondary reservoirs in bedclothes and floor dust and that these desiccated bacterial particles are less susceptible to the action of glycol vapors than are microorganisms contained in fine droplets. Therefore, a second series of experiments was undertaken in which the action of triethylene glycol vapor was supplemented by measures designed to prevent the dispersal of lint and dust into the air. It was hoped that in this manner it might prove possible to rid the air of a hospital ward completely of hemolytic streptococci even in the presence of a population heavily infected with these microorganisms. PLAN OF THE STUDY
Optical Transduction Schemes for Molecularly Imprinted Polymer Sensors

Molecular imprinting is a useful technique for making a chemically selective binding site. [1] The method involves building a synthetic polymeric scaffold of molecular compliments containing the target molecule with subsequent removal of the target to leave a cavity with a structural “memory” of the target. Molecularly imprinted polymers can be employed as selective adsorbents of specific molecules or molecular functional groups. Sensors for specific molecules can be made using optical transduction through chromophores residing in the imprinted site. The use of metal ions as chromophores can improve selectivity due to directional bonding. The combination of molecular imprinting and spectroscopic selectivity can result in sensors that are highly sensitive and nearly immune to interferences. [2]
Comparison of long-chain fatty acyl-CoA synthetases from rabbit heart and liver: substrate preferences and effects of Mg2+

Rabbit heart has a single, non-specific, fatty acyl-CoA synthetase (HP1) which is dependent on Mg2+, apart from the requirement for MgATP2-. Two long-chain fatty acyl-CoA synthetase activities (LP1 and LP2) can be resolved by hydroxyapatite chromatography of liver preparations; the Mg2+ requirement for these enzymes is undefined. These experiments were done to define the Mg2+ requirements of the liver enzymes and to compare them with the heart enzyme. For all three sources of enzyme and for arachidonic, oleic and palmitic acid substrates, the overall velocity of the reaction increased as [Mg2+] increased. Depending on the substrate and the source of enzyme, the increase in overall velocity could be attributed to changes in affinity or maximal velocity or both. The substrate preference of the HP1 enzyme for arachidonic acid (AA) was fifth or sixth of eight substrates regardless of the concentration of Mg2+. In contrast, increasing [Mg2+] shifted the relative substrate preference of both liver enzymes for AA. At low [Mg2+], AA was ranked seventh or eighth (least preferred) of eight substrates, whereas at high [Mg2+], AA was ranked as fifth or sixth. Hill plots of competition studies were consistent with Mg2+-induced positive co-operativity in LP1, but not in HP1 or LP2. Although enzymes from the three sources exhibit substantial kinetic differences, it is uncertain whether they are three different enzymes.
KAP investigation about smoking and tobacco control among medical workers in Liuzhou City

[Objective]To understand the knowledge,attitude and practice(KAP) about medical workers' smoking and tobacco control,and provide evidence for tobacco control interventions.[Methods]The stratified multistage random sampling method was adopted to select 1 hospital of municipal first-class,second-class and third-class,respectively.The obtained data were analyzed statistically by one-on-one investigation.[Results] The total smoking rate of medical staff was 20.5%,the smoking rate 19.3%,male 42.7%,female 1.6%.The maximum of smoking rate was 28.0% in 40-49 years age group,and the lowest was 10.2% in 20-29 years age group.The smoking rate of medical and technical staff was 47.2%,that of them with associate senior professional title was 47.6%.[Conclusion]The medical workers are lack of knowledge of health hazards of smoking and tobacco control.The smoking and tobacco control education and smoking cessation training should be strengthened to improve their knowledge levels,to guide active smoking cessation,so as to drive other smokers to quit smoking.
On the inhibition of (Na plus, plus, K plus)-activated adenosine triphosphatase by diisopropyl fluorophosphate.

The (Na + + K + )-activated transport ATPase from guinea pig kidney cortex is inhibited in the presence of high concentrations of diisopropyl fluorophosphate (DFP) if Mg ++ is present, although the inhibition is caused not by DFP but by the fluoride released in its hydrolysis. Fluoride at 1 mM inhibits transport ATPase in a few minutes. The second-order rate constant for inhibition is 2.7 x 10 2 M -1 min -1 . Mg ++ is necessary for the inhibition and K + markedly increases the rate of inhibition, but Na + is without effect. ATP prevents inhibition by fluoride, and fluoride inhibition can be reversed slowly. 14 C-DFP even without Mg ++ rapidly labels one or more proteins in the ATPase preparation, but there is no evidence that these proteins are involved in the ATPase activity.
Reading Comes Naturally: A Mother and Her Blind Child's Experiences:

Based on experiences with her own blind child, the author offers suggestions to other parents and teachers on activities to do with young visually impaired children that will help promote early dev...
Kernel-induced vector spaces

Introduction The notion of kernel-induced vector spaces is the cornerstone of kernel-based machine learning. Generalization of the traditional definition of a similarity metric plays a vital role in facilitating the analysis of complex and big data. It is often necessary to generalize the traditional Euclidean inner product to the more flexible and nonlinear inner products characterized by properly chosen kernel functions. The new inner product leads to a new distance metric, allowing the data analysis to be effectively performed in a higher-dimensional vector space. The topics addressed in this chapter are as follows. Section 2.2 introduces Mercer's fundamental theorem stating the necessary and sufficient condition for a function be a Mercer kernel. It will examine several prominent kernel functions, including the polynomial and Gaussian kernel functions. Section 2.3 introduces the notion of intrinsic space associated with a kernel function. The intrinsic space is so named because it is independent of the training dataset. The dimension of the space is denoted by J and will be referred to as the intrinsic degree . This degree, whether finite or infinite, dictates the training efficiency and computational cost. Section 2.4 introduces a finite-dimensional kernel-induced vector space, known as empirical space , which is jointly determined by the kernel function and the training dataset. The dimension of the empirical space is equal to the data size N . With the LSP condition, both the intrinsic-space and the kernelized learning model will be at our disposal.
The Style Is the Ad

Advertising, written in the language of a movie, a celebrity, a profession or any familiar style transferred from another context, can be created more easily and can communicate more effectively th...
KP Solitons on $$\mathrm{Gr}(N, 2N)_{\ge 0}$$

In this chapter, we will discuss the reflective symmetry \((x, y, t) \leftrightarrow (-x,-y,-t)\) of the KP equation, and show that this symmetry is a consequence of the duality between the Grassmannian \(\mathrm{Gr}(N, M)\) and \(\mathrm{Gr}(M-N, M)\) in terms of the KP solitons. Using this duality, we construct the KP solitons for \(\mathrm{Gr}(M-N, M)_{\ge 0}\) from those for \(\mathrm{Gr}(N, M)_{\ge 0}\). We then consider a special class of KP solitons for \(\mathrm{Gr}(N, 2N)_{\ge 0}\), which consists of the same set of the asymptotic solitons at both \(y\ll 0\) and \(y\gg 0\), i.e. \(\mathscr {S}_+=\mathscr {S}_-\). The soliton solutions of this type are referred to as N-soliton solutions. The simplest ones of these solutions consist of N line-solitons having non-resonant interactions among those solitons and are generated from the points in an irreducible component of the lowest dimension, N, of \(\text {Gr}(N, 2N)_{\ge 0}\). We also discuss some combinatorial properties of those solutions. For the simplest cases of non-resonant interactions, the total number of such N-soliton solutions is given by a Catalan number \(C_N=\frac{1}{N+1}\left( {\begin{array}{c}2N\\ N\end{array}}\right) \).
Why are missionaries in America? A case study of a Korean mission movement in the United States:

Why are missionaries coming to the United States? Why is the country that is a top missionary-sending nation also a top missionary destination? Based on an in-depth case study of one of the largest...
Managing the IBD Patient with Ostomy Complications

The inflammatory bowel disease patient with a stoma will at some point develop a peristomal or stomal complication. Up to 63% of all people living with a fecal diversion will develop a peristomal skin alteration, including, but not limited to, denuded peristomal skin, peristomal pyoderma gangrenosum, peristomal abscess, or a fungal infection. Stomal complications, though not consistently reported in the literature, generally develop well after stoma creation and can include stenosis, retraction, fistula, and prolapse. Assessment of the stoma and peristomal skin should be part of the examination of the inflammatory bowel disease patient to determine the presence of complications as well as plan the appropriate intervention. This chapter will cover the following conditions: stomal retraction and stenosis, prolapse, fistula, and peristomal pyoderma gangrenosum. Dehydration in the person with an ostomy is a common reason for hospital readmission, and management of high stoma output will be covered.
Dependence of the Electronic and Optical Properties of Methylammonium Lead Triiodide on Ferroelectric Polarization Directions and Domains: A First Principles Computational Study

Organic–inorganic perovskites, and in particular methylammonium (MA) lead triiodide, recently emerged as promising for thin-film solar cell applications and, as a result, have attracted much attention. However, some important phenomena have been less examined in these systems, e.g., effects of ferroelectric domains on the optoelectronic properties. In this work, we investigate the effects of the polarization direction in single domains, and of uncharged and charged ferroelectric domains, on the electronic and optical properties of MA lead triiodide by first principles calculations. Highly accurate quasiparticle band gap calculations enabled characterization of the electronic structure of charged and uncharged domains in comparison to single domains. Additionally, analysis of the effects of a potential on the Born effective charges and respective density of states provided an understanding of changes in the band gap, as dependent on the type of domain, and on the MA moiety direction. Agreement between expe...
Call to restore NIH's cap on grant funding

In her In Depth News story “NIH abandons grant cap, offers new help to younger scientists” (16 June, p. [1108][1]), J. Kaiser reported that the National Institutes of Health (NIH) reversed its decision to cap grant funding according to the Grant Support Index and replaced it with the Next
Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome.

Sjogren's syndrome (SS) is a chronic, autoimmune exocrinopathy that leads to severe dryness of the mouth and eyes. Exocrine function is highly regulated by neuronal mechanisms but little is known about the link between chronic inflammation, innervation and altered exocrine function in the diseased eyes and exocrine glands of SS patients. To gain a better understanding of neuronal regulation in the immunopathogenesis of autoimmune exocrinopathy, we profiled a mouse model of spontaneous, autoimmune exocrinopathy that possess key characteristics of peripheral neuropathy experienced by SS patients. Mice deficient in the autoimmune regulator (Aire) gene developed spontaneous, CD4+ T cell-mediated exocrinopathy and aqueous-deficient dry eye that were associated with loss of nerves innervating the cornea and lacrimal gland. Changes in innervation and tear secretion were accompanied by increased proliferation of corneal epithelial basal cells, limbal expansion of KRT19-positive progenitor cells, increased vascularization of the peripheral cornea and reduced nerve function in the lacrimal gland. In addition, we found extensive loss of MIST1+ secretory acinar cells in the Aire -/- lacrimal gland suggesting that acinar cells are a primary target of the disease, Finally, topical application of ophthalmic steroid effectively restored corneal innervation in Aire -/- mice thereby functionally linking nerve loss with local inflammation in the aqueous-deficient dry eye. These data provide important insight regarding the relationship between chronic inflammation and neuropathic changes in autoimmune-mediated dry eye. Peripheral neuropathies characteristic of SS appear to be tightly linked with the underlying immunopathological mechanism and Aire -/- mice provide an excellent tool to explore the interplay between SS-associated immunopathology and peripheral neuropathy.
Formal Verification of the Pentium® 4 Floating-Point Multiplier

We present the formal verification of the floating-point multiplier in the Intel IA-32 Pentium® microprocessor. The verification is based on a combination of theorem-proving and BDD based model-checking tasks performed in a unified hardware verification environment. The tasks are tightly integrated to accomplish complete verification of the multiplier hardware coupled with the rounder logic. The approach does not rely on specialized representations like Binary Moment Diagrams or its variants.
Designing an Honors Peer Advising Center

Journal of the European Honors Council 2017 (volume 1) - Issue 2. Special issue: Honors communities The second issue of the Journal is devoted to papers and notes related to presentations at the International Honors Conference at Windesheim UAS, the Netherlands, in June 2017.
Virtual customer environment design and organizational innovation: An exploration–exploitation perspective

Many firms are developing virtual customer environments (VCEs) that provide customers the opportunity to submit, discuss, and vote for new ideas. Some studies show that VCEs promote the development...
Maze or Labyrinth: Identifying PTSD Stressors in the Built Space of Zaatari and Calais Refugee Camps

In this study, we analyze the structure of paths within two refugee camps (Calais, France, and Zaatari, Jordan) as a preliminary study examining posttraumatic stress disorder (PTSD) stressors withi...
Infections in Vascular Surgery

Technical advances in vascular surgery in recent years have enhanced our ability to care for patients with car- diovascular diseases. Theextensive use of medical devices and prosthetic materials has resulted in longer survival of such patients and has also improved their quality of life. However, infection remains the most serious com- plication of prosthetic grafts and devices, because it dra- matically alters the patient’s outcome. Infections are often severe and in some cases life-threatening, while their cure may be problematic if removal of the infected material is not feasible. The incidence of infection varies with the indication of implantation and the site of the implant, be- ing more common after emergency procedures, when the prosthesis is anastomosed with the femoral artery and when placed subcutaneously. The true incidence may be higher than that reported, because many graft infections are not apparent until several years after implantation.
#StayWoke: The Language and Literacies of the #BlackLivesMatter Movement

This paper examines the language, literacies, communicative, and rhetorical practices of the Black Lives Matter (BLM) movement. The work pays attention to the communication practices of the BLM and Hip Hop generation in its extension of Black and African American language traditions and prior liberation movements in their unapologetic performance of Black chants, Black grammar, phonology, vocabulary, Black fashion and music, to die-ins, hands-up, and the technologization of the movement through social media, Black Twitter, hashtags, and memes. The language and literacies of the Black Lives Matter movement represent diverse identities within Black community, vernacular associated with various economic and educational classes, diaspora, culturally rooted, Hip Hop generations, cis-gendered women, men, as well as LGBTQ and gender non-conforming. In this way, the language and literacies of BLM promote the value of ALL Black lives.
Cross-sectional areas of deep/core veins are smaller at lower core body temperatures.

The cardiovascular system plays a crucial role in thermoregulation. Deep core veins, due to their large size and role in returning blood to the heart, are an important part of this system. The response of veins to increasing core temperature has not been adequately studied in vivo. Our objective was to noninvasively quantify in C57BL/6 mice the response of artery-vein pairs to increases in body temperature. Adult male mice were anesthetized and underwent magnetic resonance imaging. Data were acquired from three colocalized vessel pairs (the neck [carotid/jugular], torso [aorta/inferior vena cava (IVC)], periphery [femoral artery/vein]) at core temperatures of 35, 36, 37, and 38°C. Cross-sectional area increased with increasing temperature for all vessels, excluding the carotid. Average area of the jugular, aorta, femoral artery, and vein linearly increased with temperature (0.10, 0.017, 0.017, and 0.027 mm2 /°C, respectively; P < 0.05). On average, the IVC has the largest venous response for area (18.2%/°C, vs. jugular 9.0 and femoral 10.9%/°C). Increases in core temperature from 35 to 38 °C resulted in an increase in contact length between the aorta/IVC of 29.3% (P = 0.007) and between the femoral artery/vein of 28.0% (P = 0.03). Previously unidentified increases in the IVC area due to increasing core temperature are biologically important because they may affect conductive and convective heat transfer. Vascular response to temperature varied based on location and vessel type. Leveraging noninvasive methodology to quantify vascular responses to temperature could be combined with bioheat modeling to improve understanding of thermoregulation.
Introducing Post-World War II Women’s Pages

Women’s pages have been a part of American newspapers since the 1880s. These sections largely focused on household news and articles that reinforced a woman’s place in the home. World War II led women journalists to cover beats denied to them previously. When they were forced back to the women’s pages during peacetime, they took their experiences with them and redefined women’s news. The women’s pages of the 1950s and 1960s reflected a changing role for women and created a foundation for the Women’s Liberation Movement.
Motivation and Change Management

The purposes of this chapter are (1) to describe some of the main contributions of Edwards Deming, (2) to clarify the motivating potential score and the implications for job design, (3) to explain the relevance of the field of human factors engineering, and (4) to offer brief highlights from the change management literature. Each of these subjects relates to topics on the ASQ Certified Quality Engineer (CQE) exam. Also, these topics are relevant to lean six sigma projects and general discussions of business management.
Communicative Capitalism and Revolutionary Form

This essay considers the political form that is presupposed in questions of resistance and revolution. It situates resistance and revolution in communicative capitalism, a setting characterised by ...
Vascular Endothelial Growth Factor-A Deficiency in Perivascular Adipose Tissue Impairs Macrovascular Function.

Objective: Thoracic perivascular adipose tissue (PVAT) has been shown to release factors that influence the functioning of neighboring vascular tissue. Cardiovascular complications of obesity are on the rise; therefore, this study set out to determine if adipose-specific ablation of vascular endothelial growth factor-A (VEGF-A) plays a role in the maintenance of aortic structure and function. Methods: Adipose-specific VEGF-A-deficient mice were previously generated. Fabp4cre(+). VEGF flox/flox and Fabp4cre(-). VEGF flox/flox mice were maintained on chow diet. PVAT gene expression was measured with real-time quantitative PCR. Aortic vasomotor response was assessed with isometric tension measurements. Collagen deposition was analyzed histologically in the vascular media and compared using ratiometric pigment density. Results: PVAT-specific adiponectin expression was decreased in Fabp4cre(+). VEGF flox/flox mice. Isometric tension measurements revealed a dose-dependent dysfunction in response to acetylcholine within the distal aortic segment of Fabp4cre(+). VEGF flox/flox . Fabp4cre(+). VEGF flox/flox mice exhibited increased aortic deposition of collagen within the thoracic adventitial and medial spaces. Conclusion: These data demonstrate that decreased expression of VEGF-A within the surrounding adipose tissue microenvironment of the thoracic aorta has a detrimental effect on aortic integrity and vascular function. Modulation of angiogenic pathways within PVAT may offer an important avenue toward the treatment of adipose tissue dysfunction in obesity and its vascular complications.
Murky Transparencies: Clarity using Performance Engineering

This position paper highlights a daunting challenge facing the deployment of open distributed applications: the performance management component of the transparency functions. Applications operating in an ODP environment require distribution transparencies possessing comprehensive performance management capabilities including monitoring and modeling. The transparency functions are controlled by adaptive management agents that react dynamically to meet client QoS requirements given a current set of server and channel QoS capabilities. This technical challenge must work in a open environment with multiple autonomous administrative domains. For this goal to be realized, the ODP architecture must be enhanced. Distributed performance management of “operational” communications has been neglected in favor of the trendy multi-media “streams” communication in spite of the dominance of the former in current and future applications.