cssi/SciSciGPT-SciSciNet huggingface dataset:
Evidence for progestogen secretion by ACTH-stimulated adrenals.

Conclusions1. Daily doses of 30 γ of an ACTH suspension in beeswax and peanut oil injected for a week stimulated the adrenals of immature hypophysectomized and oophorectomized rats to form progestogen(s) as shown by the deciduoma test. 2. MH in daily doses as low as 50 γ accomplished this effect in immature hypophysectomized-adrenalectomized rats, the ovaries of which had previously been luteinized with PMSG. 3. Progesterone and DOCA in 7 daily doses of one mg induced deciduoma formation in immature hypophysectomized rats; hydrocortisone in 7 daily doses of 5 mg did not. 4. Since both MH and ACTH induce progestogen secretion, an assayist should study the respective target tissue of each (corpus luteum or adrenal cortex) for histologic evidence of activation rather than use biologic or chemical evidence of progestogen formation. An alternative would be to test for MH progestogen in hypophysectomized-adrenalectomized animals, and for ACTH-progestogen after hypophysectomy and oophorectomy.
The Response of Turkey Poults to Virginiamycin in Diets Containing Various Levels of Supplemental Methionine

Two experiments were conducted with day-old Nicholas Large White turkey poults. A 2 x 3 factorial arrangement of treatments was used in Experiment 1 (0 and 22 ppm of virginiamycin and 0, .06, and .12% supplemental DL-methionine). A 2 x 4 factorial arrangement of treatments was used in Experiment 2 (0 and 22 ppm of virginiamycin and 0, .04, .08, and .12% DL-methionine). A corn-soybean meal diet was used that contained no supplemental choline and a sulfate-free trace mineral mix. The experiments were conducted for 21 days. Body weight was increased by virginiamycin and by all levels of supplemental methionine. However, feed efficiency was not influenced.
Cotton Leaf Crumple Virus Disease in Okra-leaf and Normal-leaf Cottons

Cotton leaf crumple virus (CLCV) was transmitted in a greenhouse by the sweetpotato whitefly, Bemisia tabaci (Gennadius), to seedlings of cotton plants, Gossypium hirsutum L., representing five normal-leaf cultivars and their okra-leaf isolines. Infected and control plants were moved to the field and compared with each other. CLCV-infected plants were 25% shorter, produced 47% fewer open bolls, and yielded 50% less seedcotton than the control plants. Disease symptoms were expressed less in two okra-leaf isolines than in their normal-leaf cultivars, but yields were not significantly different.
Inheritance of Resistance to Bacillus thuringiensis in Diamondback Moth (Lepidoptera: Plutellidae)

We tested the offspring of various crosses of Plutella xylostella (L.) to determine the mode of inheritance of resistance to a commercial formulation of the microbial insecticide Bacillus thuringiensis . The progeny of reciprocal F 1 crosses (resistant male ° susceptible female and resistant female ° susceptible male) responded alike in bioassays, indicating autosomal inheritance. The LCso of F 1 progeny was not significantly greater than the LCso of a susceptible strain, showing that resistance was recessive. Responses of progeny from a backcross (F1 ° resistant strain) corresponded more closely to predictions from a single-locus model than to predictions from models with 2, 5, or 10 loci. Deviations between observed and expected outcomes increased as the number of loci in the model increased. Estimation of the minimum number of effective factors ( sensu Lande 1981) also suggests that the number of loci influencing resistance was not large. In summary, our results suggest that resistance was controlled primarily by one or a few loci.
Origin, development, and impact of mountain laurel thickets on the mixed-oak forests of the central Appalachian Mountains, USA

Abstract Throughout forests of the northern hemisphere, some species of ericaceous shrubs can form persistent understories that interfere with forest regeneration processes. In the Appalachian Mountains of eastern North America, mountain laurel (Kalmia latifolia) may interfere in the regeneration of mixed-oak (Quercus spp.) forests. To verify this possibility, I conducted a dendroecology study from 2001 to 2005 in three mixed-oak stands with mountain laurel thickets to elucidate how and when the thickets originated, developed, and were impacting hardwood seedlings. At all three sites, the oldest mountain laurel dated to the 1930s when the stands emerged from a period of recurring disturbance. However, most of the mountain laurel has originated since the 1950s when the stands were generally undisturbed. More recently, insect defoliations have accelerated the development of the thickets by increasing available sunlight. A strong negative relationship exists between the percent cover of mountain laurel and the density of hardwood seedlings with 20–30% cover being sufficient to inhibit seedling establishment and survival. Perpetuating mixed-oak forests that contain mountain laurel thickets will require reducing shrub cover to less than 20–30% at the beginning of the regeneration process to help ensure adequate densities of hardwood seedlings.
On Quality Upgrading of Mainstream Newspapers

Transfer of scientific information and dissemination of accurate information is the objective of mainstream newspapers.The largest newspapers in the construction and development of cultural status play an important role,At the era of electronic media,the largest newspapers' role as high-quality news providers and credible information are still irreplaceable for many reasons.The largest newspaper is a heavyweight media.To ensure the quality,allowing readers to enjoy quality service,the newspapers need to strengthen the front-end management,comprehensive qualities in terms of reporters and text editing to be high-profile,they should be"citizens of science literacy".
Experimental study about effect of stimulated Brillouin scattering in single frequency pulsed fiber amplifiers

In order to study the stimulated Brillouin scattering(SBS)effect on the pulse form of pulsed fiber laser amplifiers,a single frequency fiber laser amplifier system was built and its pulse waveform distortion was observed in the experiment.If continuing to improve pump power,a high power spike appeared at the distorted location,which was induced by the second-order SBS effect in a fiber.To verify this conclusion,the coupled equations contains the second-order Stokes wave were built and simulated and the results showed that the high peak power spike was the second-order Stokes wave of SBS effect.
Characterization of the microtubule binding domain of microtubule actin crosslinking factor (MACF): identification of a novel group of microtubule associated proteins.

MACF (microtubule actin cross-linking factor) is a large, 608-kDa protein that can associate with both actin microfilaments and microtubules (MTs). Structurally, MACF can be divided into 3 domains: an N-terminal domain that contains both a calponin type actin-binding domain and a plakin domain; a rod domain that is composed of 23 dystrophin-like spectrin repeats; and a C-terminal domain that includes two EF-hand calcium-binding motifs, as well as a region that is homologous to two related proteins, GAR22 and Gas2. We have previously demonstrated that the C-terminal domain of MACF binds to MTs, although no homology was observed between this domain and other known microtubule-binding proteins. In this report, we describe the characterization of this microtubule-binding domain of MACF by transient transfection studies and in vitro binding assays. We found that the C-terminus of MACF contains at least two microtubule-binding regions, a GAR domain and a domain containing glycine-serine-arginine (GSR) repeats. In transfected cells, the GAR domain bound to and partially stabilized MTs to depolymerization by nocodazole. The GSR-containing domain caused MTs to form bundles that are still sensitive to nocodazole-induced depolymerization. When present together, these two domains acted in concert to bundle MTs and render them stable to nocodazole treatment. Recently, a study has shown that the N-terminal half of the plakin domain (called the M1 domain) of MACF also binds MTs. We therefore examined the microtubule binding ability of the M1 domain in the context of the entire plakin domain with and without the remaining N-terminal regions of two different MACF isoforms. Interestingly, in the presence of the surrounding sequences, the M1 domain did not bind MTs. In addition to MACF, cDNA sequences encoding the GAR and GSR-containing domains are also found in the partial human EST clone KIAA0728, which has high sequence homology to the 3′ end of the MACF cDNA; hence, we refer to it as MACF2. The C-terminal domain of mouse MACF2 was cloned and characterized. The microtubule-binding properties of MACF2 C-terminal domain are similar to that of MACF. The GAR domain was originally found in Gas 2 protein and here we show that it can associate with MTs in transfected cells. Plectin and desmoplakin have GSR-containing domains at their C-termini and we further demonstrate that the GSR-containing domain of plectin, but not desmoplakin, can bind to MTs in vivo.
Outcomes and Risk Factors Associated with Prolonged Intubation after EVAR.

Background Time to discharge has decreased for aortic surgery since the advent of endovascular aortic aneurysm repair (EVAR), partially due to improved perioperative management. We aimed to investigate outcomes and risk factors associated with prolonged intubation following EVAR. Methods The Vascular Study Group of New England (VSGNE) database was queried to select all patients who underwent elective EVAR between January 2003 and December 2014. Patients who were not extubated in the operating room were classified as having prolonged intubation. Patients requiring prolonged intubation were compared with those extubated in the operating room using t -test and chi-square statistics. Kaplan-Meier survival analyses estimated all-cause mortality. Independent predictors associated with prolonged intubation, including postoperative pneumonia or respiratory failure, were examined using multivariable logistic regression. Results A total of 3,979 patients were identified within the elective EVAR VSGNE data set, among whom 5.2% required prolonged intubation. Patients with prolonged intubation were older, more frequently female, non-Hispanic, had larger aneurysms, and had a more frequent diagnoses of diabetes, congestive heart failure, coronary artery disease, ejection fraction P P P 3 (1.5, 1.1–1.7). Conclusions Prolonged intubation following EVAR is associated with increased risk of postoperative respiratory complications, as well as decreased long-term survival. High-risk patients for prolonged intubation, including those deemed subjectively unfit for an open procedure, ejection fraction 3, may not benefit from an elective EVAR.
Proto-Poch@ Representations in Film: Exploitation or Bust

Chapter 2 examines the positive representations of proto-poch@pop artists Ritchie Valens and Selena Quintanilla-Perez, framed in a discussion of poch@ pop filmmaker Robert Rodriguez. This chapter focuses on proto-poch@ films La Bamba and Selena because they represent the lives and music of poch@s in the U.S. who are English-dominant and achieve mainstream acceptance, while performing Spanish-language music. This examination of proto-poch@ films sets the foundation for further discussion of the poch@ trope and identity that challenge negative portrayals in mainstream representations of Latin@ language and culture.
Effects of Chronic Exposure to Silver Nanoparticles on Ruditapes decussatus Gills Using Biochemical Markers

Nanoparticles are among the particular materials produced by industrial activities; the release of these nanoparticles in natural ecosystems interacts with living organisms. Aquatic environment is the most common estuary waste medium for industrial and all human activities, the consequences may be highly effective on sea food species. Moreover, the potential in situ reduction of metallic ions by preexistent agents leads to nanoparticles which may cause hazardous effects. Many organisms become at risk especially those that use gills during respiration process such as bivalves. The study undertaken investigates the potential effect of silver nanoparticles obtained by green synthesis method on the gills of Ruditapes decussatus as a model. Nanoparticles have been synthesized using Ceratonia siliqua fruit extract as a reducing agent. The organisms have been chronically exposed to silver nanoparticles and the effects were biochemically evaluated. The tests performed show a typical behavior of catalase, glutathione reductase, and glutathione S-transferase activities that give information about the oxidative stress-induced malondialdehyde quantification, which reveals a possible membranous deterioration of the gills. Acetylcholinesterase expression has been qualified to be at a safe rate which implies the capacity of the animal to protect the cholinergic system.
Book Review: Advancing the Search for How Administrators Should Act: A Review of the Political Ethics of Public Service

What am I to be? What will I do? Will I do it? These are the questions The Political Ethics of Public Service calls public servants to ask and shows them how to answer. At once a primer for student...
NLO electroweak effects on the Higgs boson production in association with a bottom quark pair at the LHC

The dominant contribution to the Higgs production in association with the bottom quark pair at the LHC is the gluon-gluon fusion parton subprocess. We present a complete calculation of the next-to-leading order electroweak corrections to this channel. The other small contributions with quarks in the initial state are calculated at tree level. We find that the next-to-leading order electroweak corrections can suppress the leading order contributions significantly.
Carboplatin hypersensitivity reactions (HSR) in carboplatin retreatment for recurrent ovarian cancer.

5572 Background: The reported risk of HSR during carboplatin retreatment is 18-44% and increases with repeated carboplatin exposure. We aimed to prospectively study the effect of an extended increm...
Review of How Humans Learn to Think Mathematically: Exploring the Three Worlds of Mathematics

Educational theory is not my area of expertise. This is an important book on educational theory and practice, deserving an expert and thorough review. So why did I agree to review it? In answer, I quote a friend here at the University of New Mexico. “You write a book review because you want to say something about the subject of the book. But you are required first of all actually to tell about the book itself.”
Advantages to Using Social-Behavioral Models of Medication Adherence in Research and Practice

Achieving and sustaining high levels of adherence to medication regimens is essential to improving health outcomes, but continues to be a challenge for a sizable proportion of patients. Decades of research suggests that medication adherence is determined by a complex constellation of factors. Social-behavioral science research has focused on creating frameworks that identify which contextual, personal, social, or drug-related factors appear to most influence adherence. Comprehensive models of adherence propose specific structural relationships between these factors that can be used to plan for, implement, and monitor programs that seek to optimize adherence. The use of social-behavioral models offers multiple advantages in both practice and research environments; however, the breadth and depth of these models can deter many from engaging in this important exercise. To promote the use of social-behavioral frameworks and models of adherence, we provide a brief overview of the advantages in using a social-behavioral lens in adherence work, a sampling of models used in HIV medication adherence research that have high generalizability to other conditions, and practical guidance for grounding adherence promotion strategies in evidence informed by social-behavioral science research.
Social movement 2.0: integrating and assessing scholarship on social media and movement

With over five years of hindsight following historic protests around the world, we review scholarship published on “Social Movement 2.0” (SM2.0)—our shorthand for the convergence of Web 2.0 platfor...
Computer Assisted Evaluation and Computation of Pulmonary Function in the Critically Ill Neonate

At the Infant Intensive Care Unit of The Children’s Hospital of Philadelphia, approximately 500 newborn infants are admitted each year with various forms of respiratory disease, such as Respiratory Distress Syndrome, Meconium Aspiration Syndrome, and Neonatal Apnea. In these situations, when oxygen and carbon dioxide gas exchange is significantly compromised, it becomes necessary to apply respiratory support such as mechanical ventilation, continuous positive airway pressure (CPAP) and/or increased inspired oxygen concentration (FiO2) to maintain adequate vital signs.
Ramanujan: Letters and Commentary, by Bruce C. Berndt and Robert A. Rankin

(1996). Ramanujan: Letters and Commentary, by Bruce C. Berndt and Robert A. Rankin. The American Mathematical Monthly: Vol. 103, No. 8, pp. 708-713.
Exploring Traits of High-Performing, High-Poverty Schools

Over the past decade, there has been a significant increase in pressure placed on schools across the nation due to high-stakes accountability policies (Klar, 2014). It comes as no surprise that low performing schools feel constant pressure to raise the measured academic performance of all students. Rarely, do low-performing schools who have overcome challenging circumstances in order to increase academic achievement, get spotlighted. Educators need to identify the common factors attributed to increased student achievement. This can be achieved by examining the lessons and examples of high-performing schools so that all schools can succeed regardless of circumstances.
Ilmenite in ordinary chondrites.

Ilmenite composition in equilibrated ordinary chondrites, analyzing Fe, Mg, Ti and Cr content
Determinant Selection vs Clonal Deletion Models of Immune Response Gene Function

The role of Ia antigens expressed at the level of the antigen-presenting cell (APC) or macrophage has been firmly established as essential to the process of antigen recognition by T cells (1, 2). The observation that only responder but not nonresponder parental macrophages can present the relevant immune response (Ir) gene controlled antigen to (responder x nonresponder)F1 T lymphocytes suggested that the Ir gene products are functionally expressed at the level of the APC (3). Further studies on the Ir gene control of T cell responses to native and synthetic insulin polypeptides (4, 5) were consistent with the view that the ability to select and display a specific antigen epitope to the immune T cell is an Ir gene function expressed by the APC-the “determinant selection model.”
Nutrient content of monoculture corn (12 Years) as a function of nitrogen, tillage, and residue management

The effect of 12 yrs of nitrogen (N) X tillage X residue management systems on nutrient composition of monoculture corn (Zea mays L.) was investigated. Treatments included: N rates of 0 and 200 kg ha−1 yr−1; three tillages — moldboard plough, chisel plough and no tillage; and two residue treatments — returned and no residue. Initial soil phosphorus and potassium levels were very high and no further additions were made throughout the study. Grain yields did not change over time for moldboard and chisel plough tillages. Stover phosphorus content did not change over time for these systems. In contrast, stover potassium content was negatively correlated with time for all treatments. With few exceptions, stover concentrations of magnesium, manganese, zinc, copper and boron did not change with time. Nutrient levels in grain followed the general trends observed for stover, except manganese and magnesium contents decreased consistently with time.
Porphyric insecticides. 2. 1,10-Phenanthroline, a potent porphyric insecticide modulator

Abstract It is shown that in Trichoplusia ni , 1,10-phenanthroline, in addition to 2,2′-dipyridyl, exhibits potent contact porphyric insecticidal modulating properties. When sprayed with δ-aminolevulinic acid, 1,10-phenanthroline causes the larvae to accumulate massive amounts of protoporphyrin IX and lesser amounts of Zn-protoporphyrin IX in darkness and results in insect death in the light. In addition, ingestion of δ-aminolevulinic acid and 1,10-phenanthroline with the diet was extremely efficient in causing tetrapyrrole accumulation in darkness. This tetrapyrrole accumulation, in turn, was extremely efficient at producing insect death in the light, as evidenced by the low concentrations of δ-aminolevulinic acid (2 m M ) and 1,10-phenanthroline (0.2 m M ) that were sufficient to cause 100% larval mortality. Several substituted 2,2′-dipyridyls and 1,10-phenanthrolines were also shown to act in concert with δ-aminolevulinic acid in causing larval death in the light.
4.5 Mechanical Properties of Actin Networks

The actin cytoskeleton is a highly heterogeneous and composite intracellular biopolymer network. The cell utilizes several different actin structures with distinct architectures and compositions for diverse biological processes. The variety of structures suggests that the mechanical properties of the cytoskeleton are tuned for functional cell behavior. A useful biophysical approach for elucidating the mechanical properties of the cytoskeleton has been to study reconstituted in vitro actin networks. Measuring the rheology of and forces generated by these networks provides insight into the physical mechanisms that underlie the elasticity of crosslinked networks and the behavior of contractile and protrusive networks, both in vitro and in cells.
Interpretable Data-Driven Modeling in Biomass Preprocessing

Data-driven models provide a powerful and flexible modeling framework for decision making and controls in industry. However, extracting knowledge from these models requires development of easily interpretable visualizations. In this paper, we present a data-driven methodology for modeling and visualization of relative equipment workload in a biomass feedstock preprocessing plant. The methodology is designed to serve in two main fronts: (1) knowledge discovery and data-mining from instrumentation data, (2) improving situational awareness during monitoring and control of the plant. We used Gaussian Processes to create a model of the expected current overload rate of for each of the electric motors involved in the plant. The expected number of overloads on each equipment was used to quantify and visualize the relative workload of the different components of the system. The visualization is presented in the form of an intuitive directed graph, whose properties (node size, position, colors) are driven by overload rates estimations.
Correction to: HIV Persistence on Antiretroviral Therapy and Barriers to a Cure.

Correction to: Chapter 7 in L. Zhang, S. R. Lewin (eds.), HIV Vaccines and Cure, Advances in Experimental Medicine and Biology 1075, https://doi.org/10.1007/978-981-13-0484-2_7.
Proximal Interphalangeal Arthrodesis of Lesser Toes Utilizing K-Wires Versus Expanding Implants: Comparative Biomechanical Cadaveric Study:

Background:Lesser toe proximal interphalangeal (PIP) joint arthrodesis is one of the most common foot and ankle elective procedures often using K-wires for fixation. K-wire associated complications...
Redox Dependent Modifications of Ryanodine Receptor: Basic Mechanisms and Implications in Heart Diseases

Heart contraction vitally depends on tightly controlled intracellular Ca regulation. Because contraction is mainly driven by Ca released from the sarcoplasmic reticulum (SR), this organelle plays a particularly important role in Ca regulation. The type two ryanodine receptor (RyR2) is the major SR Ca release channel in ventricular myocytes. Several cardiac pathologies, including myocardial infarction and heart failure, are associated with increased RyR2 activity and diastolic SR Ca leak. It has been suggested that the increased RyR2 activity plays an important role in arrhythmias and contractile dysfunction. Several studies have linked increased SR Ca leak during myocardial infarction and heart failure to the activation of RyR2 in response to oxidative stress. This activation might include direct oxidation of RyR2 as well as indirect activation via phosphorylation or altered interactions with regulatory proteins. Out of ninety cysteine residues per RyR2 subunit, twenty one were reported to be in reduced state that could be potential targets for redox modifications that include S-nitrosylation, S-glutathionylation, and disulfide cross-linking. Despite its clinical significance, molecular mechanisms of RyR dysfunction during oxidative stress are not fully understood. Herein we review the most recent insights into redox-dependent modulation of RyR2 during oxidative stress and heart diseases.
Evaluation of Oxygen Uptake Kinetic Asymmetries in Patients with Multiple Sclerosis: A Pilot Study

Background of Study: Observations of limb to limb differences (bilateral asymmetry) in leg strength, power, peak oxygen uptake (VO2) and bone mineral density has been reported in individuals with Multiple Sclerosis (MS). Objetives: The purpose of this study was to quantify the magnitude of bilateral asymmetries in oxygen uptake (VO2) kinetics response to single leg cycling (SLC) in relapsing-remitting multiple sclerosis (MS) patients. Methods: Five MS patients (2 men, 3 women; age 43±7 yrs) performed constant work rate SLC trials to determine VO2 kinetics in each leg. Asymmetry scores were used to quantify the magnitude of the bilateral asymmetries. Results: Significant asymmetries were seen in VO2 peak and parameters of VO2 kinetics. VO2peak asymmetry score was significantly different than 0% (p=0.015). Similarly, significant asymmetry for VO2 kinetic response to exercise as mean response time was observed (p=0.03). In addition the VO2 response to exercise resulted in a significant asymmetry in VO2 deficit between legs (p=0.03). No correlation between EDSS scores and any asymmetry scores existed. Conclusions: These findings provide insight into the potential differences in metabolic perturbation and limb specific symptomatic fatigue within the MS population.
What Could Go Wrong? Exploring the Downsides of Autonomous Vehicles

While autonomous vehicles have the potential to greatly improve our daily lives, there are also challenges and potential downsides to these systems. In this workshop, we intend to foster discussions about the potential negative aspects of autonomous cars in hopes of surfacing challenges that should be considered during the design process rather than after deployment. We will spur these conversations through a review of participant position statements and through group discussion facilitated by a card game called “What Could Go Wrong?” Our goal is to consider the autonomous vehicle’s benefits—improving safety, increasing mobility, reducing emissions—against potential drawbacks. By identifying potential harms and downsides, the workshop attendees, and the AutoUI community more broadly can design well-considered solutions.
An update on the Active Magnetospheric Particle Tracer Explorers (AMPTE) program.

The principles involved in the AMPTE mission's active experiments are discussed together with the role of the AMPTE satellites (the Germany's Ion Release Module, IRM, the United Kingdom Subsatellite, and the U.S Charge Composition Explorer, CCE) in and the results of the ion-release experiments. The AMPTE orbit profile is described, with the times of solar-wind and magnetotail ion releases (two barium and two lithium releases were carried out as the IRM precessed through the magnetosheath) shown schematically. In addition to the results on the Van Allen radiation belts obtained through the ion-release experiments, studies of the radiation belts with the new generation of sensors aboard the CCE and IRM are described.
Statistics for Environmental Teratogenesis

Teratology is the study of adverse effects of environmental agents on the developing system. The major source of information for studying potential teratogenic (developmental) effects of chemicals on humans is generally the animal dose–response experiments. Quantitative risk assessment involves an assessment of the relationship between exposure and adverse health effects to derive an allowable exposure level. Acceptable levels of human exposure are derived by dividing the lower confidence limit benchmark dose by the product of several uncertainty factors. This article describes the statistical models and benchmark approach for quantitative risk assessment of developmental effects. The benchmark dose method involves selection of a dose–response function to fit animal experimental data. The benchmark dose and its lower confidence limit are then estimated from the fitted dose–response model. The dose–response function for continuous response data is modeled using the litter-based analysis. The dose–response function for dichotomous response data is modeled using beta binomial. Keywords: developmental and reproductive study; benchmark dose; beta-binomial model; continuous response data; dichotomous response data; dose–response model; point-of-departure
Constructing the Genome Commons

In this chapter, I engage the theoretical framework of the commons (as established by Ostrom and later scholars) to elucidate both the structural and the narrative elements of the genome commons, the public aggregation of human genomic data. I chart the evolution of this public resource from what was initially a public domain vehicle established to deter the proprietary designs of emerging biotechnology companies, into a unique polycentric governance institution for the growth, management, and stewardship of a massively shared public resource.
Andreev Bound States at the Onset of Phase Coherence in Bi(2)Sr(2)CaCu(2)O(8).

A new technique of planar tunneling spectroscopy has been developed to access the in-plane density of states of optimally doped Bi 2 Sr 2 CaCu 2 O 8 single crystals. The low energy spectrum is observed to depend on crystallographic orientation. When tunnel current is injected nominally along the Cu-Cu bond direction, a zero-bias conductance peak is observed to appear simultaneously with the onset of bulk superconductivity. These data demonstrate the existence of surface-induced states in this system and confirm the d-wave symmetry of the superconducting order parameter.
Division Delay Induced in Escherichia coli by Near-Ultraviolet Radiation

Cell division delay without lethality in Escherichia coli induced by near UV radiation, noting growth delay and photoprotection
Right Ventricular Septal Pacing: In Lieu of Biventricular Pacing for Cardiac Resynchronization in a Patient With Right Bundle Branch Block? *

A 71-year-old male with ischemic cardiomyopathy, severe systolic left ventricular dysfunction and symptomatic heart failure was not considered a good candidate for implantation of a biventricular pacing system to effect cardiac resynchronization due to underlying right bundle branch block (RBBB). He received instead a dual-chamber implantable cardioverter defibrillation with the ventricular lead placed at an alternate site position at the high right ventricular septum. This resulted in significant narrowing of the QRS duration (resynchronization) with a good clinical response over short-term. The case illustrates a possible alternative approach to biventricular pacing for cardiac resynchronization in patients with RBBB.
QR and Inverse QR Algorithms

This chapter contains sections titled: Inverse QR Algorithm QR Algorithm Extended QR Algorithm Appendix: Array Kalman Filters
The Potential Use of Earth Observing System Data to Monitor the Passive Emission of Sulfur Dioxide from Volcanoes

Long-term monitoring of the passive emission of SO2 is essential if volcanologists are to establish baseline emission rates and correlate changes in emission rates with the behavior of a volcano.
Robust template based corner detection algorithms for robotic vision

Image corners encapsulate gradient changes in multiple directions. Therefore, corners are considered as efficient features for use in robotic navigation algorithms. Template based corner detection has a low computational complexity and is straightforward to implement. With the appropriate design of templates, satisfactory detection accuracy can also be achieved. In this paper, we introduce two new template based corner detection algorithms to be used to assist robot vision: the matching based corner detection, namely, MBCD; and the correlation based corner detection, namely, CBCD. These two approaches outperform existing template based approaches in the means that they reduce detection of spurious corners by considering ideal corners with at least two-pixel length on the corner arm directions. Experimental results show that the proposed algorithms detect essential corners for synthetic images and natural images satisfactorily according to human visual perception. We also examine the robustness of the two corner detection approaches in terms of the average repeatability and localization error. Since our approaches are computationally efficient, it makes these template based corner detection algorithms suitable for real time support in robotic applications. Comparisons with existing corner detection algorithms are also presented.
High repetition rate LPP source facility for EUVL

In this work we present the status of our high repetition-rate/high power EUV source facility. The masslimited target concept has demonstrated high conversion efficiencies (CE) previously, with precision solid state lasers. Currently, experiments are in progress with high power high repetition-rate (3-4 kHz) Qswitched laser modules. We present a new dedicated facility for the high power EUV source. Also, we present a precision EUV energy-meter, which is developed for absolute EUV energy measurements. Spectral measurements of the tin-doped droplet laser plasma are performed with a flat-field spectrometer (FFS) with a back-illuminated CCD camera. We address the issue of maintaining the calibration of the EUV optics during source operation at non-optimum intensity at high repetition-rate, which is required for CE improvement studies. Here we present the unique metrology for measuring EUV energies under a variety of irradiation conditions without degrading EUV optics, even at high repetition rates (multi-kHz).
Allergic fungal sinusitis with extensive bone erosion of the clivus presenting with diplopia.

Objective:We report a case of allergic fungal sinusitis causing bone erosion and diplopia.Case report:A 43-year-old man presented with a four-month history of increased nasal congestion and progressive diplopia. Clinical examination revealed bilateral nasal polyposis and a right lateral gaze deficit, consistent with a VIth cranial nerve palsy. Computed tomography of the paranasal sinuses demonstrated a large sellar mass with extensive bony erosion and both supra- and infra-sellar extension. An endoscopic approach to the sphenoid sinus, clivus and posterior cranial fossa with image guidance was performed, enabling surgical treatment involving nasal polypectomy, wide marsupialisation of the sphenoid sinus and removal of the extensive allergic fungal mucin. The patient awoke from anaesthesia with complete resolution of his diplopia.Conclusion:Otolaryngologists should be aware that approximately 20 per cent of patients with allergic fungal sinusitis demonstrate paranasal sinus expansion and bone erosion involving surrounding anatomical structures. Such patients may have clinical findings involving the orbit and cranial vault.
Anaerobic processes for the dechiorination of 1,1, 1‐trichioroethane

Abstract Chlorinated aliphatic hydrocarbons are common groundwater and soil water contaminants, as a consequence of poor waste management, fortuitous spills or leaking storage tanks. Anaerobic environments have been observed to catalyze the removal of chlorine from these compounds by reductive dechlorination. The reductive dechlorination of 1,1,1‐trichlorethane (TCA) has been investigated with the intent of demonstrating applicability for remediation of contaminated ground‐water/soil systems. In closed, batch reactors, TCA was dechlorinated under methanogenic but not under denitrifying conditions. Microbial cultures were developed from the same seed, without extensive subculturing. Results confirm the importance of redox potential in biotic reductive dechlorination. Dechlorination of TCA was demonstrated in two upflow columns packed with glass beads [GB] and a mixture of glass beads and activated carbon [GB/GAC]. Hydraulic residence time was 2.5; columns were fed a TCA substrate solution for a period of 4...
Hard photon radiative correction to wide angle pair production

Abstract This paper summarizes the result of an exact calculation of the hard photon radiative correction to pair production. The result is surprisingly simple and suggests a more general applicability.
Bayesian analysis of hierarchical poisson models with latent variables

A Bayesian analysis of count data using a hierarchical model with latent variables has been proposed. The model allows for fixed covariates as well as direct modeling of latent variables as a function of covariates which are considered as primary importance. A Gibbs sampling algorithm with adaptive rejection sampling method is suggested to find posterior densities of parameters and latent variables. The proposed method is applied to epileptic seizure data arising from a study of progabide as an adjuvant therapy for seizure episodes.
Electrobehavioral characteristics of epileptic rats following photothrombotic brain infarction

Abstract The goal of this study was to characterize the electroencephalographic (EEG) and behavioral properties of young adult rats during extended video-EEG monitoring following photothrombotic brain infarction. Two-month-old male Sprague–Dawley rats underwent photothrombotic brain infarction of the left sensorimotor cortex with the photosensitive dye rose bengal ( n =10) or were used as controls ( n =9). Qualitative and quantitative EEG analysis was performed on digital video-EEG records obtained during 6 months of recording. The main finding of this study was that 5/10 (50%) lesioned animals developed focal epileptic seizures ipsilateral to the cortical infarct characterized by rhythmic spike-wave discharges with or without behavioral change. Epileptic animals demonstrated increased delta, theta, and low beta-range power ipsilateral to the infarct that reliably distinguished them from lesioned nonepileptic and control animals. Lesioned animals (epileptic and nonepileptic) also demonstrated a distinct pattern of focal rhythmic theta activity before or after generalized high beta-range discharges. Electrical and behavioral characteristics common to both lesioned and control animals included: (1) focal rhythmic theta activity in either hemisphere; (2) focal low beta-range discharges in either hemisphere; (3) generalized high beta-range discharges; (4) absence seizures; (5) generalized pseudoperiodic spike discharges associated with mild multifocal body jerks; (6) tonic-clonic seizures (one naive control; one lesioned animal). Cresyl violet staining of lesioned animals' brains showed consistent infarcts of the sensorimotor cortex extending to the subcortical white matter. These results provide an expanded electrobehavioral description of young adult rats following photothrombotic brain infarction and augment further investigation into the molecular, cellular, and network alterations that contribute to the establishment of post-stroke epilepsy.
Sensitivity Of matrix eigenvalues

A recent paper by Donald Gignac describes some difficulties with a certain matrix eigenvalue problem. This paper shows that the difficulties result from the naturue of the matrix itself. Quantities called condition numbers, which measure the sensitivity of the eigenvalues, are computed, and numerical results given.
Effect of thyroidectomy on the kinetics of ADP-ATP translocation in liver mitochondria.

Abstract The role of adenine nucleotide translocase (AdNT) in the reduced oxidative metabolism of hypothyroidism has been examined. Both AdNT and respiratory activities in liver mitochondria of thyroidectomized rats were 30% below normal. Mitochondrial AdNT activities were determined by the back-exchange method of Pfaff and Klingenberg ( Eur. J. Biochem. 6 , 66, 1968 ). The K m and V max of the enzyme were temperature dependent. At physiological temperature, the K m and V max of the normal rat AdNT were 10 μ m (for external ADP) and 4.73% s −1 (percentage efflux of the labeled adenine nucleotides), respectively. AdNT in hypothyroid rat liver mitochondria exhibited a 25–35% lower V max and 75% higher K m when assayed over the temperature range 0 to 37 °C. Dixonplot studies indicated that the AdNT in hypothyroidism was two- to threefold more sensitive to atractylate and palmitoyl-CoA inhibitions. In contrast the ADP-ATP translocase in hypothyroidism was more resistant than the control carrier to bongkrekate inhibition. The decrease in the transport of ADP, which is consistent with the decreased oxidative activity associated with hypothyroidism, apparently occurs secondary to changes in the lipid matrix of the inner mitochondrial membrane ( F. L. Hoch (1977) Arch. Biochem. Biophys. 178, 535. ).
Recent Trends in Four Common Stability Indices Derived from U.S. Radiosonde Observations

Abstract Daily sounding-derived atmospheric stability indices are typically employed for short-term severe weather forecasts. Over longer time periods, these indicators may convey changes in the potential for severe storm development over the United States. Daily (0000 UTC) observations from 48 radiosonde stations in the contiguous United States are extracted to assemble a ∼50 yr record of four common stability indices: the Lifted Index, the K-Index, convective available potential energy (CAPE), and the Air Force Severe Weather Threat Index. Because of radiosonde data inhomogeneities, the 1973–97 period is the focus of the analysis. Trends in the mean and extreme values of daily index observations are calculated for spring and summer seasons. In addition, climatological mean indices, as well as the mean frequency of index extremes, are determined for all U.S. regions. At stations free of obvious data discontinuities, the early part of the record (1948–65) is compared with more recent periods. In spring, f...
Oxidation of primary aliphatic amines with sodium perborate

Abstract A biphasic system of ethyl acetate and water containing sodium perborate, sodium bicarbonate and N,N,N′N′-tetraacetylethylenediamine oxidizes primary aliphatic amines to aliphatic C-nitroso compounds in good to excellent yields.
L-serine production by a methionine-auxotrophic mutant of methylotrophic Pseudomonas

A methionine-auxotropic mutant deficient in homocysteine transmethylation activity was induced from a methylotrophic L-serine-producing derivatives of Pseudomonas MS31. This mutant grown with limited L-methionine had more than 1.7-fold higher serine hydroxymethyltransferase (SHMT) activity than its parent strain. The elevated SHMT activity significantly contributed to the improvement of L-serine accumulation from glycine and methanol. Under the optimum conditions, this mutant accumulated up to 23.9 mg/ml of L-serine. The yield coefficient L-serine from consumed glycine was 89% (mol/mol). The maximum conversion rate of added glycine (19 mg/ml) to L-serine was 77% (mol/mol).
Smoke-free homes, strength of smoke-free law, and children in the home.

Introduction Secondhand smoke (SHS) is a leading cause of childhood illness and premature death, especially in rural areas. The study examined the relationship of having a smoke-free home, strength of smoke-free law (SFL) in the county of residence, having one or more minor children in the home, rural/urban location, and demographics. Methods An Internet-based panel survey was administered to Kentucky residents from 2007 to 2012. Sample size ranged from 400 to 513 per year; N = 2,653 total. Most were female, aged 35-54, had at least some college education, and lived in a smoke-free home. Almost half lived in a county with a comprehensive SFL; 14% lived in a county with a moderate or weak law. Results Multivariate logistic regression revealed that the significant predictors of a smoke-free home included having education beyond high school, being a nonsmoker, living in an urban county, and having a year of participation in the survey. Controlling for smoking status and other personal characteristics, those who responded to the survey in the last 2 years of administration were more likely to have a smoke-free home compared to the reference year of 2007. Respondents living in urban counties were nearly 2 times more likely to report a smoke-free home than rural dwellers. Conclusions Smoke-free homes in urban areas, where SFLs may be the norm, may be more typical than in rural communities. Public awareness campaigns and education about the benefits of smoke-free homes is needed, especially in rural areas, targeting smokers, those with less education, and those with children living in the home.
Purification and preliminary characterization of human leukocyte elastase

Abstract Affinity chromatography permits the purification of 1–3 mg of human leukocyte elastase from the leukocytes contained in 500 ml of whole blood. Lysosomal granule proteins are extracted from polymorphonuclear leukocytes and subjected to chromatography on a column of elastin-Sepharose. Contaminating proteins are eluted with buffer containing 1 m NaCl and then elastase activity is eluted with buffer containing 8 m urea. The enzyme retains all of its esterase activity against N -t-BOC- l -alanine p -nitrophenyl ester after exposure to 8 m urea and retains 22% of its activity in the presence of 1% sodium dodecyl sulfate. In sodium dodecyl sulfate and 2-mercaptoethanol leukocyte elastase undergoes autolysis giving rise to several low molecular weight fragments. The molecular weight of the native enzyme is found to be 22.000 by both gel filtration and sodium dodecyl sulfate—acrylamide gel electrophoresis. A characteristic set of four isozymes is seen after acrylamide disc gel electrophoresis at pH 4.5. All bands are active against elastin and also contain carbohydrate by the periodic acid-Schiff stain. On the basis of stain intensity, the slower moving isozymes appear to be richest in carbohydrate. Active leukocyte elastase forms a complex with α 1 -antitrypsin in a 1:1 molar ratio. The elastase must be enzymatically active for complex formation to occur.
Myo-inositol transport in the lens of galactose-maintained rats.

Lens myo-inositol (MI) content is regulated by a pump-leak system consisting of an active Na-depen-dent MI transport and its passive permeability through the membrane. We measured the active MI uptake and membrane permeability in lenses of rats maintained on a 50% galactose diet for 1, 3 and 7 days. After only 1 day of galactose feeding, active MI uptake in the lens was reduced dramatically by 74% compared to age-matched control lenses; by day 3, active Ml transport was decreased by 89% and it was undetectable by day 7. The passive membrane permeability was determined by measuring (a) the passive Ml influx and (b) the 3H-sorbitol flux. After 1 day of galactose feeding, the membrane permeability increased such that within 3 days it increased to 5–6 fold. Galactose feeding also led to a rapid increase in lens polyol content. After 1 day, lens polyol increased to 53 μmol/g wet wt compared to a control value of 0.35 μmol/g wet wt and increased further to 65 and 72 μmol/g wet wt after 3 and 7 days of galactose...