cssi/SciSciGPT-SciSciNet huggingface dataset:
Error Understanding in Computer Integrated Manufacturing Processes

An increasing national priority on quality in product design and manufacturing requires significant advancement and new understanding to provide a supporting theoretical foundation and definitive science base. The effort to achieve needed productivity and performance advancement in contemporary computer integrated manufacturing embraces a continuum of disciplines that provides new levels of process performance. This includes a comprehensive definition of CADAM error accountability, feature design information at the process interface, apriori system linkages with aposteriori statistical process control, and integration of the advanced concepts of qualitative process theory with sensor fusion for complementing online domain knowledge. With online tracking of parameter variations a digital controller can then be adapted to maintain system error within a predetermined bound.
Predicting and postdicting the effects of word frequency on memory.

In the experiments reported here, I replicate and extend recent results that reveal that judgments about the memorability of common and uncommon words differ qualitatively depending on whether they are made during study or elicited during a recognition test (Guttentag & Carroll, 1998). When assessing recognition ability for individual words, subjectspredict superior performance for common words, butpostdict better performance for uncommon words. This interaction suggests that subjects rely on different cues when making judgments during study than they do when making analogous judgments during the recognition test, and that the cues utilized during recognition lead judgments to be more accurate. The shift is then evident in later predictions: Subjects who make postdictions consequently correctlypredict superior recognition performance for uncommon words on a subsequent study list. When subjects are asked to make later predictions aboutrecall performance, however, having made postdictions on a test of recognition does not mislead subjects into predicting superior recall performance for uncommon words.
Kinesin-Like Protein 6 (KIF6) Polymorphism and the Efficacy of Rosuvastatin in Primary Prevention

Background— Hypothesis-generating data raise the possibility that carriers of the kinesin-like protein 6 ( KIF6 ) 719 arginine (Arg) allele preferentially benefit from statin therapy, and, on this basis, a commercial assay for KIF6 has been developed. Methods and Results— In the recently completed JUPITER trial, men and women without prior cardiovascular disease or diabetes who had baseline low-density lipoprotein cholesterol <130 mg/dL and high-sensitivity C-reactive protein ≥2 mg/L were randomly allocated to rosuvastatin 20 mg daily or to placebo and followed for first major vascular events (nonfatal myocardial infarction, nonfatal stroke, hospitalization for unstable angina, arterial revascularization, or vascular death) and for all-cause mortality. We evaluated the effect of polymorphism at rs20455 encoding the KIF6 719Arg allele on outcomes in this primary prevention trial, both among Caucasian participants and in the trial as a whole. Among 8781 Caucasian trial participants, we observed no increase in vascular event rates among carriers of the KIF6 719Arg allele as compared with noncarriers (hazard ratio, 0.91; 95% confidence interval, 0.66 to 1.26) nor any difference in percent low-density lipoprotein cholesterol reduction with rosuvastatin according to genotype (−52 versus −52 mg/dL, P =0.11). Rosuvastatin allocation was associated with an almost identical reduction in the trial primary end point among carriers (hazard ratio, 0.61; 95% confidence interval, 0.43 to 0.87) as among noncarriers (hazard ratio, 0.59; 95% confidence interval, 0.39 to 0.88) ( P -interaction=0.90). Genotype had no impact on rosuvastatin efficacy in further analyses that included all-cause mortality, in analyses conducted in the total trial cohort that adjusted for race, or in analyses using generalized models of inheritance rather than recessive models. Conclusions— In the large primary prevention JUPITER trial, rosuvastatin was equally effective at reducing cardiovascular event rates among carriers and noncarriers of the KIF6 719Arg allele. Thus, at least for rosuvastatin, there appears to be no clinical utility to screening for KIF6 genotype as a method to determine vascular risk or to predict statin efficacy. Clinical Trial Registration— URL: . Unique identifier: [NCT00239681][1]. [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access_num=NCT00239681&atom=%2Fcirccvg%2F4%2F3%2F312.atom
Principlism and the Ethics of Librarianship

Moral dilemmas are a seemingly intractable part of librarianship. Although professional codes of ethics offer some guidance as to the nature of librarians’ professional obligations, they are generally silent when it comes to moral decision making at the point of service. This article will argue that librarians must augment their normative professional codes with a rational decision procedure when faced with a moral dilemma involving a library service. In particular, the ethical approach of principlism—the dominant ethical approach in medical ethics—is well-suited to librarianship. Pursuant to the principlist approach, this article will qualify the nature of moral dilemmas, establish the limits of professional codes of ethics, identify a candidate set of core principles of library service, and outline the core principlist concepts of specifying obligations and balancing principles.
Knowledge spillover in corporate financing networks: embeddedness and the firm's debt performance

Building on social embeddedness theory, we examine how the competencies and resources of one corporate actor in a network are transferred to another actor that uses them to enhance transactions with a third actor—a strategic process we dub ‘network transitivity.’ Focusing on the properties of network transitivity in the context of small-firm corporate finance, we consider how embedded relations between a firm and its banks facilitate the firm's access to distinctive capabilities that enable it to strategically manage its trade-credit financing relationships. We apply theory and original case-study fieldwork to explore the types of resources and competencies available through bank–firm relationships and to derive hypotheses about how embedded bank–firm relationships affect the strategy of small- to medium-sized firms. Using a separate large-scale data set, we then test the generalizability of our hypotheses. Our qualitative analyses show that embedded bank–firm ties provide special governance arrangements that facilitate the firm's access to bank-centered informational and capital resources, which uniquely enhance the firm's ability to manage trade credit. Consistent with our arguments, our statistical analyses show that small- to medium-sized firms with embedded ties to their bankers were more likely to take lucrative early-payment trade discounts and avoid costly late-payment penalties than were similar firms that lacked embedded ties—suggesting that social embeddedness beneficially affects the financial performance of the firm. Copyright © 2002 John Wiley & Sons, Ltd.
Active microwave sensing of the Earth's surface--A mini review

Radar has been used for remotely sensing the surface of the land and sea since the middle of World War II, but only since the mid-1960's has this technique become widely used for civil purposes. The nature of radar backscatter and theoretical models that have been used to describe it are briefly described. The state of knowledge of radar return from both land and sea is summarized. The principal radar remote sensing instruments are briefly described. A summary is presented of applications of sidelooking radar to observing the land and of various radar sensors (SLAR, scatterometers, altimeters) to observing the sea. Finally, the future of this technique is assessed both in terms of the applications and instruments to be expected during the remainder of the 1970's and the following decade and in terms of research that is needed for radar remote sensing to realize its full potential.
Walls of Crisis: Street Art and Urban Fabric in Central Athens, 2000–2012

Street art, an offspring of the global metropolis and a product of its socio-urban fabric, has inevitably grown on, and been sustained by, urban architecture. Individual taggers and graffiti crews have proliferated in European cities since the 1980s. In the beginning, they mirrored their North American counterparts’ socio-political preoccupations that were a product of deteriorating socio-economic and socio-urban conditions in depressed sectors of metropolitan areas. In the early 1990s, however, with economic development and the beginnings of urban regeneration processes came the first large-scale mutation of tagging into ‘graffiti art’. With larger and more recognizable works, and visual rather than textual content, by the late 1990s graffiti was accepted by increasingly broader sections of urban population as ‘street art’. A new form of public art, street art could claim a legitimate part in the forming and transforming of urban identities in both their visual and their spatial iterations.
Studies on the photoprotective mechanism of butylated hydroxytoluene.

It has been suggested that butylated hydroxytoluene (BHT)‡, a phenolic antioxidant that conveys photoprotective properties to skin, may act by altering epidermal parameters that influence the level of ultraviolet light (UV) reaching critical target sites. The potential diminution of effective UV dose could account for the observed inhibition of UV-induced ornithine decarboxylase (ODC). Thus studies were conducted to examine the possibility that BHT was capable of promoting epidermal proliferation, just as others have shown with lung epithelial cells. UV-induction of ODC, in unrestrained Skh-Hr-I mice irradiated with Westinghouse FS–20 lamps, was shown to be linearly responsive from 0.3 to 0.6, J/cm2/dose. The degree of inhibition afforded by dietary BHT was approximately constant over this dose range. In addition, intraperitoneal administration of BHT (400 mg/kg) inhibited UV-induced ODC as greatly as when provided dietarily. Greatest inhibition occurred when BHT was administered at least 46 h prior to UV exposure, with the inhibitory event(s) requiring over 20 h to become effective. However, BHT had no effect, during this time interval, upon the incorporation of [3H]thymidine or leucine into DNA and protein, respectively. Nor were BHT effects reflected in the epidermal labeling index. These data suggest that BHT does not induce epidermal proliferation. An alternate explanation, in which the antioxidant properties of BHT play a major role, is proposed.
On Some Fundamental Concepts of Darwinian Biology

There are two approaches to the study of the structures, functions, and interrelations of living beings—the Cartesian or reductionist and the Darwinian or compositionist. This does not mean that some biological sciences are reductionist and others compositionist, or that there are Cartesian and Darwinian phenomena. Biological phenomena do have, however, Cartesian and Darwinian aspects. Some biologists view their subject more from the reductionist and others from the compositionist side, and some are more adept at using Cartesian and others Darwinian methodologies.
Effect of plaster cast on tourniquet shock.

SummaryTourniquet shock in rats cannot be prevented by a rigid cast applied to the hind extremity immediately after removal of the tourniquet. The effect of the cast is to reduce the rapidity rather than the ultimate magnitude of local fluid loss. Survival time of the animals is prolonged but there is no decrease in mortality. The development of shock is accompanied by hemoconcentration and rise in serum creatine both of which occur more gradually than in control rats without casts.
Dielectric dependence of single-molecule photoluminescence intermittency: nile red in poly(vinylidene fluoride).

The dependence of single-molecule photoluminescence intermittency (PI) or "blinking" on the local dielectric constant (e) is examined for nile red (NR) in thin films of poly(vinylidene fluoride) (PVDF). In previous studies, variation of the local dielectric constant was accomplished by studying luminophores in chemically and structurally different hosts. In contrast, the NR/PVDF guest-host pair allows for the investigation of PI as a function of e while keeping the chemical composition of both the luminophore and host unchanged. The solvatochromic properties of NR are used to measure the local e, while fluctuations in NR emission intensity over time provide a measure of the PI. PVDF is an ideal host for this study because it provides submicron-sized dielectric domains that vary from nonpolar (e ≈ 2) to very polar (e ≈ 70). The results presented here demonstrate that the local dielectric environment can have a pronounced effect on PI. We find that the NR emissive events increase 5-fold with an increase in e from 2.2 to 74. A complex dependence on e is also observed for NR nonemissive event durations, initially increasing as e increases from 2.2 to 3.4 but decreasing in duration with further increase in e. The variation in emissive event durations with e is reproduced using a photoinduced electron-transfer model involving electron transfer from NR to PVDF. In addition, an increase in NR photostability with an increase in e is observed, suggesting that the dielectric environment plays an important role in defining the photostability of NR in PVDF.
Xanthine derivatives that selectively inhibit cyclic GMP hydrolysis potentiate cardiac contractile effects of isoproterenol but not those of bethanecol.

This study examines the abilities of xanthines to alter contractile and cyclic nucleotide responses to isoproterenol or bethanecol in left atria isolated from rabbits. Two of the xanthines studied (1-methyl-3-isobutyl-8-methoxymethylxanthine, and 1-methyl-3-isobutyl-8- t -butylxanthine) inhibited cyclic GMP hydrolysis more potently than cyclic AMP hydrolysis; another xanthine, theophylline, was equipotent at inhibiting the hydrolysis of the two cyclic nucleotides. All of the xanthines studied comparably potentiated contractile and cyclic AMP responses to isoproterenol (10 -8 M), regardless of their potencies to inhibit cyclic GMP hydrolysis. These data indicate that cyclic GMP is not antiadrenergic. The selective inhibitor, 1-methyl-3-isobutyl-8-methoxymethylxanthine, at a concentration that elevated cyclic GMP content to a level that was 3-fold above that observed with bethanecol alone, failed to depress contractile force, alter cardiodepressant effects of bethanecol, or alter atrial cyclic GMP content in the presence of this choline ester. These results demonstrate that the inhibition of cyclic GMP phosphodiesterase neither produces negative inotropic effects nor enhances the cardiodepressant effects of cholinergic agents.
All-or-None Phenomena in the Psychotherapy of Severe Disorders

The phenomenon of splitting, referring to “good” and “bad” attitudes toward others or toward oneself, is a prominent feature in borderline personality disorders, as well as in the schizophrenias. My thesis is that splitting is only one aspect of the broader concept of the all-or-none phenomenon. Our diagnostic abilities and therapeutic efforts will improve if we recognize the many clinical manifestations of all-or-none phenomena. Among these I will present examples of cognitive aspects, affective features, narcissistic manifestations, and aspects of superego- and ego-ideal functions. In addition, I will cite a few references about all-or-none phenomena appearing in the psychiatric literature, and will consider developmental relationships to splitting. Finally, I will focus on some implications for psychotherapeutic techniques with these patients.
CHAPTER 16 – EPIDEMIOLOGY OF APHID – BORNE VIRUSES*

Publisher Summary This chapter discusses the epidemology of aphid-borne viruses. The epidemiology of aphid-borne virus diseases can best be viewed as the interaction of the virus, host, vector, environment, actions and cultural practices of the grower, and the effects of time. The chapter discusses the relationship of each of these variables with one or more of the others, with the total picture demonstrating the epidemiology of virus diseases. Only with complete knowledge of the impact of these factors upon the epidemiology of each correctly identified virus disease can meaningful and effective control measures be initiated. Viruses diseases have been conveniently classified into virus groups that have similar affinities. The classification based on types of vectors and vector-virus relationships in the case of aphid-transmitted virus diseases along with virus groupings will be quite helpful. Aphids can acquire viruses in less than a minute and can transmit them just as quickly. Because viruses are transmitted by many different aphid species, they are said to have a low level of vector specificity. Continued examination of all the interacting components contributing to the dissemination of plant viruses is necessary to give a valid picture of what is happening in nature.
Material expertise: An ontological approach to stakeholder participation in marine policy

Abstract This paper utilizes the work of Bruno Latour to develop an ontology for the development of non-credentialed expertise. In the field of marine policy studies there is a wide body of scholarship advocating the importance of including stakeholder knowledge in the formation of public fishery policies. Despite the many calls for increased stakeholder involvement in fisheries and marine policy development, there remains a relative lack of scholarship that explores how the stakeholder expertise develops and how its quality might be assessed in policy settings. Employing Latour's concepts of material mediation, translation, and inscription to describe the connections between materiality, experience, and expertise this paper offers an ontological explanation of what constitutes non-credentialed expertise. By analyzing the Snook and Gamefish Foundation's deployment of non-credentialed stakeholder expertise in two Florida fisheries management debates from an ontological perspective this paper suggests a materially oriented heuristic for identifying and evaluating stakeholder expertise in marine policy settings.
Introduction: The Social Work of Desire

This chapter serves to frame Frances Perkins’s social work within the history of economic rights in the United States, highlighting each’s considerations of centrifugal and centripetal rights, examining closely the difference between the two. The New Deal’s framework coincides with this discussion of personal rights with detailed analysis of the economic mindset of historical figures in shaping FDR’s policy and Perkins’s social work. By providing background to the New Deal, particularly in its social work underpinnings, the chapter puts it in the context of the history of personal rights in America and in Perkins’s perspective.
Hand-off analysis for CBWL schemes in cellular communications

Channel borrowing without locking (CBWL) allows real-time borrowing of channels from adjacent cells without channel locking in co-channel cells. The schemes provide enhanced traffic performance in homogeneous environments and also relieve hot-spot traffic. Simple channel management and easy implementation are additional features. Two types of hand-off arise in CBWL, intercell hand-offs and intracell hand-offs. A model based on multidimensional birth-death processes is devised and traffic performance characteristics showing blocking and forced termination probabilities are obtained. The results, which are validated by simulation, indicate that CBWL can provide significantly improved traffic and hand-off-performance in comparison with non-borrowing cellular schemes. >
Using intelligent multi-agent systems for shipboard power systems reconfiguration

Many approaches have been taken on the reconfiguration of power systems, but most of these approaches use a centralized method. While these methods can be acceptable for terrestrial power system applications, doing reconfiguration on shipboard power systems has a different set of issues involved. For naval ships, that may experience damage during battle, a centralized reconfiguration method provides a limitation. Based on these constraints researchers are investigating decentralized control strategies that allow for reconfiguration using localized information. One newer technology that is showing promise in this area is intelligent multi-agent (IMA) systems. This paper discusses efforts underway at Mississippi State University to use IMA systems for reconfiguration of the power system. Agents are being implemented in multiple formats including Matlab and JADE to investigate the issues related to data sharing, communications and reconfiguration strategies
Explicit and Implicit Verbal Response Inhibition in Preschool-Age Children Who Stutter.

Purpose The purpose of this study was to examine (a) explicit and implicit verbal response inhibition in preschool children who do stutter (CWS) and do not stutter (CWNS) and (b) the relationship b...
Minimally Invasive Approaches to Chest Wall and Superior Sulcus Tumors

The resection of chest wall tumors, including superior sulcus tumors, has traditionally been performed via an open approach given the extent of structures to be removed. Recently, more advanced experience with minimally invasive techniques (both VATS and robotic) have allowed thoracic surgeons to perform these operations through smaller incisions and avoid the trauma to the overlying major muscles of the chest wall. One of the earliest reports of VATS-assisted chest wall resection by Widmann et al. described performance of wedge resection of lung with VATS followed by en bloc removal of ribs 3 and 4 along with the wedge of lung, which was accomplished without the use of rib spreading [1]. More recently, Hennon et al. reported a series of 17 patients who underwent VATS chest wall resection, which comprised 36 % of overall chest wall resections done at their institution from 2007 to 2013 [2]. The utilization of minimally invasive techniques for chest wall resection has become a more common phenomenon, as surgeons explore the ways in which it may benefit patients in terms of postoperative pain and morbidity. The phrase “minimally invasive chest wall resection” (MICWR) is a bit misleading, as any chest wall resection by definition requires the resection of the same amount of bone and intercostal muscle as in an “open” operation; however the method by which this is accomplished can take advantage of some of the same tools and techniques by which VATS surgery is performed, and hence we will use the term since it reduces the morbidity of cutting muscle.
Evaluation of Audio Denoising Algorithms for Application of Unmanned Aerial Vehicles in Wildlife Monitoring

Unmanned Aerial Vehicles (UAVs) have become popular alternative for wildlife monitoring and border surveillance applications. Elimination of the UAV’s background noise for effective classification of the target audio signal is still a major challenge due to background noise of the vehicles and environments and distances to signal sources. The main goal of this work is to explore acoustic denoising algorithms for effective UAV’s background noise removal. Existing denoising algorithms, such as Adaptive Least Mean Square (LMS), Wavelet Denoising, Time-Frequency Block Thresholding, and Wiener Filter, were implemented and their performance evaluated. LMS and DWT algorithms were implemented on a DSP board and their performance compared using software simulations. Experimental results showed that LMS algorithm’s performance is robust compared to other denoising algorithms. Also, required SNR gain for effective classification of the denosied audio signal is demonstrated.
A Computational Study on the Addition of HONO to Alkynes toward the Synthesis of Isoxazoles; a Bifurcation, Pseudopericyclic Pathways and a Barrierless Reaction on the Potential Energy Surface

Homopropargyl alcohols react with t-BuONO to form acyloximes which can be oxidatively cyclized to yield ioxazoles. The mechanism for the initial reaction of HONO with alkynes to form acyloximes (e.g., 13c) has been explored at the B3LYP/6-31G(d,p) + ZPVE level of theory. The observed chemoselectivity and regioselectivity are explained via an acid-catalyzed mechanism. Furthermore, the potential energy surface revealed numerous surprising features. The addition of HONO (8) to protonated 1-phenylpropyne (18) is calculated to follow a reaction pathway involving sequential transition states (TS6 and TS8), for which reaction dynamics likely play a role. This reaction pathway can bypass the expected addition product 21 as well as transition state TS8, directly forming the rearranged product 23. Nevertheless, TS8 is key to understanding the potential energy surface; there is a low barrier for the pseudopericylic [1,3]-NO shift, calculated to be only 8.4 kcal/mol above 21. This places TS8 well below TS6, making the valley-ridge inflection point (VRI or bifurcation) and direct formation of 23 possible. The final tautomerization step to the acyloxime can be considered to be a [1,5]-proton shift. However, the rearrangement in the case of 17h to 13c is calculated to be barrierless, arguably because the pathway is pseudopericyclic and exothermic.
Geometrical Rectification Of Spin-Scan Images From Pioneer II

AbstractImages of Saturn received from Pioneer 11 suffer from geometrical distortions due to thecurvilinear scan lines and the unequal sampling intervals in orthogonal directions, whichare inherent in spin -scan imaging. In this paper we discuss geometrical image rectifica-tion by polynomial transformation based on control points. Factors that affect the accu-racy of reconstruction are shown to include the spatial distribution and spatial densityof control points, and the order of the polynomial distortion model. A computer implemen-tation of the technique is described.IntroductionDistortions observed at the output of any image acquisition system may be categorizedas either radiometric or geometric. Data processing directed toward the former correctsfor nonuniformity in detector response, and therefore involves some form of transformationof the image intensity distribution. Geometric operations are those processes that alterthe spatial relationships between objects within an image. In the case of digital images,this involves the spatial redistribution of pixels in order to achieve the required scenegeometry. A widespread application of geometrical transformation by digital computers isfound in the area of Landsat image registration,' where the geometries of several imagesof the same area produced at different dates under varying optical conditions are trans-formed in order to match a reference geometry, usually that of one of the image set.
Submucosal fibroid, menorrhagia, anemia, and dysmenorrhea

The clinical case of a 32-year-old nulliparous female with heavy abnormal uterine bleeding, anemia, and dysmenorrhea, and a 4 cm submucosal fibroid is presented. The key clinical components are reviewed regarding classical presentation of heavy prolonged bleeding with associated painful cramping, as well as examination findings and diagnostic workup. Consideration of the differential diagnosis of leiomyoma, adenomyoma, focal adenomyosis, and leiomyosarcoma is reviewed. The approach to management of uterine fibroids including medications, surgery, or minimally invasive embolization or ablative techniques is reviewed. Surgical treatment with transcervical resection of submucous leiomyoma is discussed in detail.
Real-time imaging of yeast cells reveals several distinct mechanisms of curing of the [URE3] prion

The [URE3] yeast prion is the self-propagating amyloid form of the Ure2 protein. [URE3] is cured by overexpression of several yeast proteins, including Ydj1, Btn2, Cur1, Hsp42, and human DnaJB6. To better understand [URE3] curing, we used real-time imaging with a yeast strain expressing a GFP-labeled full-length Ure2 construct to monitor the curing of [URE3] over time. [URE3] yeast cells exhibited numerous fluorescent foci, and expression of the GFP-labeled Ure2 affected neither mitotic stability of [URE3] nor the rate of [URE3] curing by the curing proteins. Using guanidine to cure [URE3] via Hsp104 inactivation, we found that the fluorescent foci are progressively lost as the cells divide until they are cured; the fraction of cells that retained the foci was equivalent to the [URE3] cell fraction measured by a plating assay, indicating that the foci were the prion seeds. During the curing of [URE3] by Btn2, Cur1, Hsp42, or Ydj1 overexpression, the foci formed aggregates, many of which were 0.5 μm or greater in size, and [URE3] was cured by asymmetric segregation of the aggregated seeds. In contrast, DnaJB6 overexpression first caused a loss of detectable foci in cells that were still [URE3] before there was complete dissolution of the seeds, and the cells were cured. We conclude that GFP labeling of full-length Ure2 enables differentiation among the different [URE3]-curing mechanisms, including inhibition of severing followed by seed dilution, seed clumping followed by asymmetric segregation between mother and daughter cells, and seed dissolution.
Directed Conservative Causal Core Gene Networks

Motivation: Inferring large scale directional networks with higher accuracy has important applications such as gene regulatory network or finance. Results: We modified a well-established conservative causal core network inference algorithm, C3NET, to be able to infer very large scale networks with direction information. This advanced version is called Ac3net. We demonstrate that Ac3net outperforms C3NET and many other popular algorithms when considering the directional interaction information of gene/protein networks. We provide and R package and present performance results that are reproducible via the Supplementary file. Availability: Ac3net is available at github.com/altayg/Ac3net .
Germanic seeresses through Roman eyes

Embora as mulheres da antiguidade greco-romana tenham inspirado estudos recentes, os estudiosos nao deram tanta atencao as mulheres do mundo barbaro. Este artigo examina um grupo especifico destas mulheres – "adivinhas" germânicas que prediziam o futuro, principalmente acontecimentos militares. Escritores romanos, como Cesar e Suetonio, descreveram essas adivinhas em acao. Tacito (De Germania), em particular, refere-se a uma delas Veleda, como um paradigma das mulheres germânicas. Este artigo aceita a existencia historica das adivinhas (e adivinhos) entre os antigos germânicos; rejeita alguns relatos, mas aceita outros (como Veleda, nas Historias de Tacito). O artigo conclui sugerindo a utilidade da Germanistica e da Arqueologia da Idade do Ferro, para o estudo das mulheres germânicas.
Prevention of the progression of renal injury in diabetic rodent models with preexisting renal disease with chronic endothelin A receptor blockade

The endothelin (ET) system has emerged as a therapeutic target for the treatment of diabetic nephropathy (DN). The present study examined whether chronic endothelin A (ETA) receptor blockade with a...
Reflective microwave ghost imaging with dynamic metasurface apertures

We demonstrate phaseless, single-frequency ghost imaging at microwave frequencies using a dynamic metasurface aperture. This aperture comprises a simplified hardware architecture for generating diverse speckle patterns by tuning an array of resonant metamaterial elements.
Effects of agriculture and wetland restoration on hydrology, soils, and water quality of a Carolina bay complex

We compared hydrology, soils, and water quality of an agricultural field (AG), a two-year-old restored wetland (RW), and two reference ecosystems (a non-riverine swamp forest (NRSF) and a high pocosin forest (POC)) located at the Barra Farms Regional Wetland Mitigation Bank, a Carolina bay complex in Cumberland County, North Carolina. Our main objectives were to: 1) determine if the RW exhibited hydrology comparable to a reference ecosystem, 2) characterize the soils of the AG, RW, and reference ecosystems, and 3) assess differences in water quality in the surface outflow from the AG, RW, and reference ecosystems. Water table data indicated that the hydrology of the RW has been successfully reestablished as the hydroperiod of the RW closely matched that of the NRSF in 1998 and 1999. Jurisdictional hydrologic success criterion was also met by the RW in both years. To characterize soil properties, soil cores from each ecosystem were analyzed for bulk density (Db), total carbon (Ct), nitrogen (Nt), and phosphorus (Pt), extractable phosphate (PO4w), nitrogen (Nex), and cations (Caex, Mgex, Kex, Naex), as well as pH. Bulk density, Pt, Caex, Mgex, and pH were greatly elevated in the AG and RW compared to the reference ecosystems. Water quality monitoring consisted of measuring soluble reactive phosphorus (SRP), total phosphorus (TP), nitrate + nitrite (NOX), and total nitrogen (TN) concentrations in surface water from the AG, RW, and reference outflows. Outflow concentrations of SRP, TP, and NOX were highest and most variable in the AG, while TN was highest in the reference. This study suggested that while restoration of wetland hydrology has been successful in the short term, alteration of wetland soil properties by agriculture was so intense, that changes due to restoration were not apparent for most soil parameters. Restoration also appeared to provide water quality benefits, as outflow concentrations of SRP, TP, NOX, and TN were lower in the RW than the AG.
Novel PET/CT imaging biomarkers of CB-839 in combination with panitumumab and irinotecan in patients with metastatic and refractory RAS wildtype (WT) colorectal cancer: A phase I/II study.

TPS3616Background: Irinotecan plus panitumumab is active in RAS WT metastatic CRC (mCRC) patients who progress on 5-FU based regimens. Inevitably, patients develop resistance to EGFR inhibition; on...
Hidden Expectations: Do Teachers Use Expressive Language Ability as a Proxy for Overall Development?.

Just as paediatricians are the gatekeepers to children’s physical health, preschool teachers are the gatekeepers to children's overall developmental progress. Their perceptions shape their interact...
Adverse family events and educational outcomes of young adults: Analysis from three waves of Young Lives Data from India: Author details

Abstract There is a limited exploration in the literature of how young people’s educational outcomes respond to unexpected events or adversities in their home environment. Given the concerns about uneven educational trajectories of young people in low-income countries, such an investigation may be valuable. We analyze Young Lives data from India to contribute to this literature. We observe that over the years youth enrollment and grade attainment decline and several of them experience adversities in the form of economic loss and death and illness of a parent. Males experience similar levels of adversities as females, but their educational outcomes are generally superior to females in their cohort. Individual fixed-effects regression results indicate male enrollment is associated negatively with death of a parent. Overall however we find limited significant associations between the adversities and educational outcomes we focus on. We conclude the paper with our study’s limitation and way forward for future research.
Optimization of a 3-D isothermal plug-flow model of a monolith reactor featuring first order reactions

Abstract In this work, monolith reactor optimization is carried out. A 3-D monolith reactor model is first developed for a plug flow, isothermal, reactor featuring first order irreversible volumetric and surface reactions, then solved analytically using a series-based solution method, and finally optimized by establishing a number of mathematical model properties, and carrying out a broad search of the resulting reduced two-dimensional design parameter space. It is shown that maximum conversion is attained at a fluid velocity upper bound determined by the channel’s width, height, and capital cost to compression cost ratio. For reactors featuring only a surface reaction, maximum conversion is also attained at the maximum allowable channel width, and the minimum allowable channel hydraulic diameter. The optimum reactor residence time is inversely proportional (proportional) to the channel’s optimum hydraulic diameter (the reactor’s capital cost to production ratio).
Critical Literature Review on the Definition Clarity of the Concept of Faith, Religion, and Spirituality:

The critical review of the literature describes the definition clarity of spirituality, religion, and faith. These three terms are interchangeably used in the literature. However, each of these terms has its own definitions. For example, the term spirituality has more than 13 conceptual components. It is abstract and subjective and is different from religion and faith. Spirituality can be a connection to God, nature, others, and surrounding. Spirituality is associated with quality and meaning in life. Conversely, religion is attributed to traditional values and practices related to a certain group of people or faith. Religion is guided by tradition, rules, and culture. Religion is defined as a personal set or institutionalized system of religious attitudes, beliefs, and practices. Religion is the service or worship of God or the supernatural. Faith is often associated with religion and spirituality. Faith is more personal, subjective, and deeper than organized religion and relates to the relationship with God. The concept of spirituality lacks a professional understanding. It is imperative that the holistic view of nursing must strive to understand the definition of spirituality.
Direct Measurement of Charge Reversal on Lipid Bilayers using Heterodyne-Detected Second Harmonic Generation Spectroscopy

We report the detection of charge reversal induced by the adsorption of an aqueous cationic polyelectrolyte, poly(allylamine hydrochloride) (PAH), to supported lipid bilayers (SLBs) used as idealiz...
Methotrexate Polyglutamation in a Myasthenia Gravis Clinical Trial.

Introduction Methotrexate (MTX) is an immunosuppressive and anti-inflammatory drug used to treat rheumatoid arthritis (RA) and other autoimmune conditions. MTX is transported into cells, where glutamate moieties are added and is retained as methotrexate polyglutamates (MTXPGs). In the RA literature, it has been reported that the degree of polyglutamation correlates with the anti-inflammatory effect of MTX in RA. There are no prior studies evaluating the relationship between MTXPGs and myasthenia gravis (MG) outcome measures. The objective of this study was to assess the correlation between methotrexate (MTX) polyglutamates (MTXPGs) with Myasthenia Gravis (MG) outcome measures. Methods An analysis was done of blood drawn from patients enrolled in the 12-month randomized, placebo-controlled study of MTX in MG study. Red blood cell MTXPGs were measured via ultra-performance liquid chromatography and tandem mass spectrometry. MTXPG was correlated to MG outcome measures using Spearman Correlation Coefficient. A two-group t-test was used to determine the difference in MTXPG based on clinical outcome responder definitions. Results Twenty-one polyglutamate samples were analyzed of subjects on MTX while eight samples were analyzed from subjects on placebo. Pentaglutamate had the strongest correlation with the MG-ADL (0.99), while tetraglutamate had the strongest correlation with the QMG (0.54). Triglutamate had the strongest correlation with MGC (0.76). Conclusion There were variable correlations between MTXPG1-5 and MG outcomes (rho range: 0.08 to 0.99). There are strong correlations between MTXPG and the MG-ADL, QMG, and MGC. Long chain methotrexate polyglutamates correlate better with MG outcomes.
Infectious Disease Hospitalizations, New York City, 2001-2014.

ObjectiveHospital discharge data are a means of monitoring infectious diseases in a population. We investigated rates of infectious disease hospitalizations in New York City.MethodsWe analyzed data...
Optimizing identification of resistant hypertension: Computable phenotype development and validation.

Purpose Computable phenotypes are constructed to utilize data within the electronic health record (EHR) to identify patients with specific characteristics; a necessary step for researching a complex disease state. We developed computable phenotypes for resistant hypertension (RHTN) and stable controlled hypertension (HTN) based on the National Patient-Centered Clinical Research Network (PCORnet) common data model (CDM). The computable phenotypes were validated through manual chart review. Methods We adapted and refined existing computable phenotype algorithms for RHTN and stable controlled HTN to the PCORnet CDM in an adult HTN population from the OneFlorida Clinical Research Consortium (2015-2017). Two independent reviewers validated the computable phenotypes through manual chart review of 425 patient records. We assessed precision of our computable phenotypes through positive predictive value (PPV) and test validity through interrater reliability (IRR). Results Among the 156 730 HTN patients in our final dataset, the final computable phenotype algorithms identified 24 926 patients with RHTN and 19 100 with stable controlled HTN. The PPV for RHTN in patients randomly selected for validation of the final algorithm was 99.1% (n = 113, CI: 95.2%-99.9%). The PPV for stable controlled HTN in patients randomly selected for validation of the final algorithm was 96.5% (n = 113, CI: 91.2%-99.0%). IRR analysis revealed a raw percent agreement of 91% (152/167) with Cohen's kappa statistic = 0.87. Conclusions We constructed and validated a RHTN computable phenotype algorithm and a stable controlled HTN computable phenotype algorithm. Both algorithms are based on the PCORnet CDM, allowing for future application to epidemiological and drug utilization based research.
Considerations in Management of Acute Otitis Media in the COVID-19 Era.

Objectives:To present the otologic findings of a patient with COVID-19 and complicated acute otitis media, evaluate for the presence of SARS-CoV-2 in middle ear fluid, and assess whether suctioning...
Twenty-Four Hours of Local Cohomology

Basic notions Cohomology Resolutions and derived functors Limits Gradings, filtrations, and Grobner bases Complexes from a sequence of ring elements Local cohomology Auslander-Buchsbaum formula and global dimension Depth and cohomological dimension Cohen-Macaulay rings Gorenstein rings Connections with sheaf cohomology Projective varieties The Hartshorne-Lichtenbaum vanishing theorem Connectedness Polyhedral applications $D$-modules Local duality revisited De Rham cohomology Local cohomology over semigroup rings The Frobenius endomorphism Curious examples Algorithmic aspects of local cohomology Holonomic rank and hypergeometric systems Injective moduels and Matlis duality Bibliography Index.
A dual cardiomyocyte reporter model derived from human pluripotent stem cells

Cardiovascular diseases (CVD) remain the leading cause of death in the USA. Cardiomyocytes (CMs) derived from human pluripotent stem cells (hPSCs) provide a valuable cell source for regenerative therapy, disease modeling, and drug screening. Here, we established a hPSC line integrated with a mCherry fluorescent protein driven by the alpha myosin heavy chain (aMHC) promoter, which could be used to purify CMs based on the aMHC promoter activity in these cells. Combined with a fluorescent voltage indicator, ASAP2f, we achieved a dual reporter CM platform, which enables purification and characterization of CM subtypes and holds great potential for disease modeling and drug discovery of CVD.
Can large-scale land acquisition deals improve livelihoods and lift people out of poverty in Sub-Saharan Africa? Empirical evidence from Tanzania

The recent wave of large-scale land acquisitions or land deals, popularly called ‘land grabbing’ in subSaharan Africa, has provoked vigorous debate over the potential benefits and risks to local people, with results structured by complex policy and institu­tional context. Land deals present new develop­ment challenges and aggravate old vulnera­bilities, raising critical questions for investigation. Yet empirical evidence of impacts on local populations is limited, particularly regarding how land deals affect local people’s livelihood assets, strategies, and outcomes. Guided by the sustainable livelihood approach and a quasi-experimental design, I compare livelihoods before and after a land deal project and between an affected and a control community in southwestern Tanzania. I use household surveys, focused group discussions, and key informant interviews to collect data. The ANOVA analyses revealed that the project severely deterio­rated households’ natural, financial, and social capital and had far-reaching impacts on well-being in the affected community compared to the control village. The study recommends that African countries should consider (1) scrutinizing land deals and enforcing contracts, (2) conducting rigorous envi­ron­mental and social impact assess­ment, (3) strengthening customary land rights and reinforc­ing compensation policies, and (4) mean­ingfully involving locals in land deal negotiations. This contribution responds to the deficit in research on land deals’ impacts on livelihoods and well-being and lays the groundwork for future research.
The Telemetry Control System on Omni wheel Enemy Infiltrator Robot Based on Internet of Things (IoT)

The development of sophisticated technology in the era of the industrial revolution 4.0, namely the collaboration between automation technology and the internet, causing changes in the combat and reconnaissance model to be remotely. The internet of things based omni wheel robot is divided into three module units, the main module, the data processing module, and the drive module. This concept uses a telemetry control system that is integrated with computers and the internet for data processing. The omni wheel robot is used in urban terrain for autonomous mobile surveillance operations and webcam monitoring via a web server. The omni wheel robot is designed to use four omni wheel controls and a trajectory as the main autonomous drive for the robot, the raspberry pi 3 is a microcontroller for processing programs on the robot and the webcam is used to take pictures of the terrain the robot passes through. All controls on the omni wheel robot use a telemetry system by using Wi-Fi internet network access remotely to minimize losses for TNI soldiers’ personnel in carrying out reconnaissance tasks.
Ether phospholipids govern ferroptosis

Ferroptosis is a cell death modality triggered by excessive lipid peroxidation. Two recent studies (Zou et al., 2020; Cui et al., 2021) not only reveal critical roles of ether-linked phospholipids as an additional source for providing polyunsaturated fatty acid-containing phospholipids in driving ferroptosis but also suggest a context-dependent role of TMEM189-mediated vinyl-ether phospholipid (plasmalogen) synthesis in ferroptosis.
Global games with Poisson observations: Bio-inspired distributed coordination of multi-agent systems

Global games are a class of incomplete information games where the payoffs exhibit strategic complementarity leading to an incentive for the agents to coordinate their actions. Such games have been used to model scenarios in many socioeconomic phenomena, where the private signals available to the agents are typically assumed to be Gaussian. We study an instance of a global game where the agents observe Poisson random variables, which are inspired by applications in microbiology where information signals are disseminated via discrete molecular signals rather than continuous. Although this observation model violates the essential technical assumptions present in the Gaussian case, we present preliminary results on the existence of Bayesian Nash equilibria in pure threshold policies in two variants of the underlying random state-of-the-world: an arbitrarily distributed discrete binary state and a continuous state with uniform distribution.