cssi/SciSciGPT-SciSciNet huggingface dataset:
Recent advances in medical imaging: surgery planning and simulation.

Three-dimensional display of medical image data has under gone rapid development since its introduction. This article explores the current state-of-the-art of 3-dimensional imaging applied to surgery planning and discusses the various image acquisition sources: computed tomography (CT), cine CT, magnetic resonance imaging, and ultrasound. Since increased physician involvement is the goal of the surgery planning software described, the future directions discussed emphasize the inclusion of “expert“ knowledge and ways to facilitate realistic interaction for surgery simulation.
Locus of Control and Interpersonal Attraction

Abstract The purpose of this study was to clarify the role of locus of control in interpersonal attraction. Eighth graders (N = 200 boys and girls) were administered the Nowicki-Strickland Locus of Control Scale for Children and a sociometric test that asked the students to name their best friends. It was hypothesized that the internal Ss would choose internals and that the externals would prefer fellow externals. Multiple regression analysis was used to predict the friends' locus of control, with Ss' sex, race, and locus of control as independent variables. Also, interactions between locus of control and sex (LOC × sex) and between locus of control and race (LOC × race) were added to the multiple regression equation. Finally, a curvilinear locus of control term (LOC2) was added to the equation. All of the dependent variables were significant at the .05 level. The results indicated that the Ss tended to choose friends who were similar in locus of control, but most of this tendency was due to sexual and ra...
tribal ethnicity and the state in Vietnam

Sons of the Mountains: Ethnohistory of the Vietnamese Central Highlands to 1954. GERALD CANNON HICKEY. Free in the Forest: Ethnohistory of the Vietnamese Central Highlands, 1954–76. GERALD CANNON HICKEY.
Humoral hypercalcemia complicating adenosquamous carcinoma of the proximal colon

Hypercalcemia as a complication of carcinoma of the colon is uncommon (1). It usually occurs in the presence of anorectal or rectal carcinoma that metastasizes to the lumbosacral vertebrae (2–4). Hypercalcemia complicating colon carcinoma in the absence of bone metastases—so-called humoral hypercalcemia of malignancy or paraneoplastic hypercalcemia—is rare. Only two such cases associated with adenocarcinoma of the colon (5, 6) and two cases associated with adenosquamous carcinoma of the distal colon (rectum and sigmoid) (7) have been reported. We describe the first reported case of an adenosquamous carcinoma of the cecum and ascending colon that was accompanied by severe humoral hypercalcemia. The hypercalcemia was associated with a parathyroid hormone (PTH) -like substance.
The measurement of conjectural variations in an oligopoly industry

Using independently derived estimates for the market demand elasticity and firm marginal cost, this paper measures the conjectural variations (cv's) of the eight largest U.S. steel firms for the years 1920 to 1972. Comparisons are then made between the measured cv's and those predicted by certain industry conduct hypotheses. Specifically the hypotheses are those for competitive behavior, Cournot behavior, imperfect collusion, and industry profit maximization (perfect collusion). One of the two extreme theories of firm behavior, industry profit maximization, is rejected, but the acceptance or rejection of the other theories depends on the assumptions made about the cost structure of the sample firms.
Residential preferences and neighborhood racial segregation: a test of the Schelling segregation model.

The debate over the role of the forces that create the patterns of residential separation has identified neighborhood preferences as one of the explanatory variables, but although we possess some empirical data on the nature of neighborhood racial preferences, the theoretical contributions have received only limited empirical evaluation. Among the theoretical statements. Schelling’s model of the effects of small differences in preferences on residential patterns has provided a basic building block in our understanding of preferences, choices, and patterns. Several recent surveys of residential preferences provide the data with which to evaluate the underpinnings of the Schelling model. The preference/tolerance schedules that are derived from the data have a different functional form from that suggested by Schelling, but confirm the view that stable integrated equilibria are unlikely.
Performance analysis of software for an MIMD computer

This paper presents a technique for modeling and analyzing the performance of software for an MIMD (Multiple Instruction Multiple Data) computer. The models can be used as an alternative to experimentation for the evaluation of various algorithms and different degrees of parallelism. They can also be used to study the tradeoffs involved in increasing the amount of parallel computation at the expense of increased overhead for synchronization and communication. The detection and alleviation of performance bottlenecks is facilitated.
Tolerance to response-disruptive effects of cocaine is facilitated by opportunity to respond in the absence of drug.

Abstract A dose of cocaine that was 1/8 of a logarithmic unit larger than the smallest dose that produced complete suppression of responding of pigeons under a fixed-ratio 20 schedule was administered prior to 50 daily sessions. If responding occurred, then the dose was increased by 1/8 of a logarithmic unit and administered for an additional 50 sessions. The pigeons were divided into either a ‘control’ or ‘saline’ group. Control group pigeons received the same dose of cocaine for 100 additional days. Pigeons in the saline group were also exposed to a daily dosing regimen for 100 more sessions except that saline was substituted once every 5 days. Daily dosing then continued and dose–response functions were re-determined by substituting other doses for the daily dose every fifth session. During the first exposure to each dose, tolerance was evident for five of six pigeons in the saline group, whereas sensitization was evident for pigeons in the control group. Tolerance was observed in both groups following subsequent exposures. Tolerance to effects of behaviorally large doses of cocaine was therefore promoted when saline was occasionally substituted for the daily dose. Opportunity to respond during an ongoing regimen of daily cocaine administration enhanced the development of tolerance.
What is osteopenia, and what should be done about it?

Because the term “osteopenia” is not useful as a diagnosis and can actually be harmful, I am on a personal crusade to eliminate it from the bone density lexicon.
Isolating marginally defective gate using photoperturbation induced via a C-AFM laser beam

The photoperturbation effects induced via a Conductive Atomic Force Microscope (C-AFM) laser beam, in which the surface photovoltaic effect and the carrier injection effect included in the photoperturbation can cause significant deterioration in the characterization accuracy have been widely investigated [1–5]. This study, however, successfully demonstrates how to take advantage of these non-negligible photoelectric effects to isolate marginally defective gates, which are usually difficult to uncover using the traditional approach of passive voltage contrast (PVC) carried out using a scanning electron microscope (SEM) or focused ion beam (FIB), or even when using an advanced SEM-based nanoprobing technique. Using this technique, such failures, which pose potential reliability issues on devices as the affected circuit degrades over time or under stress, can be easily screened before any quality assurance test.
Dimensions of total product knowledge in a service environment

Purpose – The purpose of the paper is to compare measures of subjective and objective knowledge as well as usage/experience measures in a credence service environment for two different samples, namely college students and non‐student adults.Design/methodology/approach – Data were collected from two independent samples using self‐administered questionnaires and were analyzed using correlation and reliability analyses, factor analysis, discriminant analysis and one‐way ANOVA.Findings – For the student sample, the results show that even though measures of subjective product knowledge, objective product knowledge, and product usage are correlated with one another, each represents one unique dimension of total product knowledge. The results for the non‐student sample show that subjective and objective knowledge converge into one dimension, product usage is a second dimension, and vicarious product knowledge a third dimension.Research limitations/implications – One limitation of the present study is that its re...
Heat capacity of well-characterized thorium metal from 298 to 700 K

Abstract The heat capacity of thorium metal has been determined by high temperature adiabatic calorimetry from 302 to 700 K on a relatively pure and well-characterized sample of the metal. The heat capacity of thorium metal from 298 to 700 K is given by Cp(Th,c) (J K−1 mol−1) = 24.905 + 4.049 × 10−3 T + 5.591 × 10−6 T2 where T is in kelvin.
The effect of stress on craving for methadone depends on the timing of last methadone dose.

Abstract Background This study examined the extent to which the timing of last methadone dose moderates the influence of a laboratory stressor on craving for methadone in a sample of methadone maintenance patients. Methods Methadone maintenance patients (N = 41) completed a computerized stress manipulation with two levels (low and high stress) on two separate days: (1) immediately following the administration of their standard daily methadone dose and (2) immediately prior to receiving their standard daily dose. The impact of stress, timing of methadone dose and their interaction were examined on self-report measures of stress and craving for methadone. Results Craving ratings varied according to the timing of last methadone dose. Immediately following methadone dose (i.e., day 1), there was no effect for stress on craving (0.12; p = 0.30). However, prior to receiving methadone dose (i.e., day 2), the high stress effect on craving was significant (1.51; p Discussion The present findings indicate that patients currently receiving methadone maintenance treatment may be particularly vulnerable to stress-related relapse immediately prior to daily methadone dosing.
A New Family of Multiferrocene Complexes with Enhanced Control of Structure and Stoichiometry via Coordination-Driven Self-Assembly and Their Electrochemistry

The design and synthesis of a new family of multiferrocene complexes with enhanced control of structure and stoichimetry via coordination-driven self-assembly is described. Insight into the structure and electronic properties of all supramolecules was obtained by electrochemical studies. The collective results provide an enhanced understanding of the influence of structural factors on the electrochemistry of multifunctional electroactive supramolecular architectures.
Positive and Negative Communicative Behaviors in Coming-Out Conversations

This essay features typographic analysis of 258 coming-out narratives from 130 diverse lesbian, gay, or bisexual participants. Two typologies of coming-out conversations, one exploring positive communicative behaviors and another exploring negative, are offered. Positive behaviors for all members of the conversation include open communication channels, affirming direct relational statements, laughter and joking, and nonverbal immediacy. Negative behaviors for those coming out included nervous nonverbal behavior, indirectly approaching the topic, and lack of preparation. Negative behaviors for receivers include expressing denial, religious talk, inappropriate questions or comments, shaming statements, and aggressive statements. Future studies and research implications are considered.
Observations of electron velocity distribution functions in the solar wind by the WIND Spacecraft: High angular resolution Strahl measurements

The WIND Solar Wind instrument (SWE) includes a sensor especially configured to measure the solar wind strahl. The strahl is the excess electron (≥100 eV) halo component of the solar wind most closely aligned with the magnetic field. Strahl electrons originate in the inner corona and move freely out to 1 A.U., providing information on the state of the corona. Electron data acquired during seven solar rotations show that the electron velocity distributions are most anisotropic and the strahl flux most intense during high speed streams. The strahl angular width is smallest when the solar wind velocity is largest, approximately 5° in width at 600 eV, and becomes much wider when the velocity is low. Coincident with the strahl is a small reverse electron flux which does not form a beam but fills the field of view. This variability of the flux and angular distribution of the strahl and anti-strahl suggests that a pitch angle scattering process may be acting to broaden the strahl and that the anti-strahl may be due to backscattering of the strahl.
InDiGO: An Infrastructure for Optimization of Distributed Algorithms

The developers of distributed algorithms are faced with two opposing forces. One is to design generic algorithms that are reusable in a large number of applications. Efficiency considerations, on the other hand, force the algorithms to be customized to specific operational contexts. This problem is often attacked by simply re-implementing all or large portions of an algorithm. This paper proposes InDiGO, an infrastructure which allows design of generic but customizable algorithms and provides tools to customize such algorithms for specific applications. InDiGO provides the following capabilities: (a) Tools to generate intermediate representations of an application which can be leveraged for analysis, (b) Mechanisms to allow developers to design customizable algorithms by exposing design knowledge in terms of configurable options, and (c) An optimization engine to analyze an application to derive the information necessary optimize the algorithms. We perform three types of optimizations: static, dynamic and physical topology-based optimization. We present experimental results to demonstrate the advantages of our infrastructure.
“Why Not Ten the Truth?”: The Autobiographies of Three Fiction Writers

(1991). “Why Not Ten the Truth?”: The Autobiographies of Three Fiction Writers. Critique: Studies in Contemporary Fiction: Vol. 32, No. 4, pp. 211-223.
Diaphragm function after interscalene brachial plexus block: a double-blind, randomized comparison of 0.25% and 0.125% bupivacaine.

Background Interscalene brachial plexus block (ISBPB) provides excellent analgesia after rotator cuff surgery but is associated with diaphragm dysfunction. In this study, ISBPB with 20 mL of 0.125% or 0.25% bupivacaine were compared to assess the effect on diaphragm function, oxygen saturation, pain control, opioid requirements, and patient satisfaction. Materials and methods In this prospective, randomized, double-blind study, 30 adults undergoing outpatient arthroscopic rotator cuff repair were enrolled to receive ultrasound-guided interscalene brachial plexus catheter placement with 20 mL of 0.125% (n = 15) or 0.25% bupivacaine (n = 15). Diaphragm function and oxygen saturation were assessed before ISBPB placement and on discharge from the postanesthesia care unit. Postoperative pain scores, opioid requirements, and patient satisfaction were compared. Results Diaphragm function and oxygen saturation were superior in the low concentration group. Absent or paradoxic motion of the diaphragm was present in 78% of the 0.25% group compared with 21% of patients in the 0.125% group ( P = .008). Oxygen saturation decreased 4.3% in the 0.25% group compared with a decrease of 2.6% in the 0.125% group ( P = .04). Pain scores averaged 1 of 10 in the 0.25% group and 0 of 10 in the 0.125% group ( P = .02). Opioid requirements and patient satisfaction were not different between the two groups. Conclusions In this randomized, double-blind comparison of ISBPB performed with 20 mL of 0.125% or 0.25% bupivacaine, diaphragm function and oxygen saturation were superior in patients treated with more dilute bupivacaine. Furthermore, there were no clinically significant differences in pain scores, and no statistically significant differences in opioid requirements and patient satisfaction.
Predictors of skin and soft tissue infections in HIV-infected outpatients in the community-associated methicillin-resistant Staphylococcus aureus era

Skin and soft tissue infections (SSTIs) are common in the era of community-associated methicillin-resistant Staphylococcus aureus (MRSA) among human immunodeficiency virus (HIV)-infected patients, but the risk factors are not well defined. We sought to elucidate the risk factors for SSTI occurrence in an HIV cohort. This investigation was a retrospective, single-center cohort study, carried out during the period 2005–2009. In this cohort of 511 HIV-infected individuals, 133 SSTIs occurred in 87 individuals over 1,228.6 person-years of follow-up, for an incidence of 108 SSTIs/1,000 person-years [95 % confidence interval (CI) 87–135]. The incidence declined significantly over time (p < 0.01). In a multivariable Cox regression, diabetes [hazard ratio (HR) 2.01; 95 % CI 1.04–3.89], psoriasis (HR 5.77; 95 % CI 1.86–17.9), lymphedema (HR 6.84; 95 % CI 2.59–18.1), intravenous catheter presence (HR 3.38; 95 % CI 1.00–11.5), and HIV viral load greater than 1,000 copies/mL (HR 2.13; 95 % CI 1.33–3.41) were most strongly associated with development of the first SSTI. Trends toward an association between SSTI risk and Medicaid insurance (HR 1.67; 95 % CI 0.98–2.83) and sexually transmitted disease during follow-up (HR 1.66; 0.99–2.78) were present. CD4+ count and trimethoprim–sulfamethoxazole use were not associated with SSTI risk. HIV-infected individuals are at high risk for SSTIs. In a primarily urban, African-American cohort, we found that a number of immunologic and demographic factors were associated with SSTI risk.
Design and Implementation of a Multiple-Beam Tuning-Fork Gyroscope

This paper presents the design, fabrication, and experimental results of a multiple-beam tuning-fork gyroscope (MB-TFG). Based on a numerical model of thermoelastic damping, a multiple-beam tuning-fork structure is designed with high Quality factors (Qs) in its two operation modes. A simple mask that defines the device through trenches is employed to implement this MB-TFG design on silicon-on-insulator wafers. The highest measured Qs of the fabricated MB-TFGs in vacuum are 255,000 in the drive-mode and 103,000 in the sense-mode, at a frequency of 15.7kHz. Under a frequency difference of 4Hz between the two modes (operation frequency is 16.8kHz) and a drive-mode vibration amplitude of 3.0μm, the measured rate sensitivity is 80μVPP /°/s with an equivalent impedance of 2.5MΩ. The calculated overall rate resolution of this device is 0.377hr°/√Hz.Copyright © 2011 by ASME
Mirror image nanostructures.

Chiral molecules that self-assemble to form chiral supramolecular structures exhibit interesting structural features reminiscent of tertiary and quaternary structures of proteins and have applicati...
Multimodal Frustration Detection on Smartphones

Detecting user's frustration on a smartphone could have a significant impact on applications such as intelligent tutoring systems or app testing systems. Our goal is to provide a multimodal frustration detection system using data exclusively retrieved from a smartphone; motion sensor readings, touch gestures and face videos recorded from the smartphone's front camera.
Microassay of acetylcholinesterase activity in small portions of single mosquito homogenates.

Abstract 1. 1. A simple, rapid microassay method is described for measuring acetylcholinesterase (AChE) activity accurately and precisely in small portions of single mosquito homogenates. 2. 2. Up to 30 microassay replicates were possible for individual insects. 3. 3. Microassay data on individual mosquitoes were compared with conventional enzyme assay data acquired using pools of the same homogenates. 4. 4. Under the optimum reaction conditions established, an average Vmax of 7.1 nmol/1/min/mosquito and an average Km of 1.3 × 10−4 M were observed with acetylthiocholine iodide as substrate. 5. 5. Variability in AChE activity within a sample population of Anopheles albimanus was observed using measurements from individual insects. 6. 6. Such information is fundamental to comparative studies of pesticide physiology (in particular, the resistance phenomenon) in the individual mosquitoes in a population pool; this technique forms the basis for a recently developed resistance microassay.
A mathematical model for λdv plasmid replication: Analysis of copy number mutants

Abstract A mathematical model based on the molecular control mechanisms for λdv plasmid replication in a single Escherichia coli cell has been applied to simulate replication of mutant λdv plasmids. Model simulations of changes in repressor level and copy number resulting from mutations in the promoter-operator P R O R region are consistent with experimental data. Calculated effects on λdv plasmid copy number of oligomer formation and of alternations in termination efficiency at t R 1 also agree with experiment. The model has been employed to simulate the influence of cro mutants and of cro and t R 1 double mutants on copy number and stable maintenance of λdv plasmid copy number. The genetic structure included in formulation of the replicon model provides a framework for relating changes in specific genetic loci on the plasmid with resulting alterations in host-plasmid system function.
Trade and foreign direct investment management strategies for U.S. processed food firms in China

Abstract This research examines the relationship between U.S. foreign direct investment (FDI) and exports of processed foods to China and identifies management strategies to enhance U.S. competitiveness. Two-stage least-squares empirical econometric results from a simultaneous equation system indicate that there exists a strong complementary relationship between U.S. exports and FDI into China. Therefore, the appropriate managerial strategy to access Chinese processed foods markets is to increase overall business activity, both FDI and exports into China.
Formation of color centers in ammonium perchlorate by x-ray irradiation at room temperature

Abstract Radiation induced color center formation has been studied in single crystal ammonium perchlorate. Large, high purity. water clear single crystals were uniformly irradiated normal to the c or 001 face with filtered 60 kV x-rays at room temperature. The radiation induced coloring, measured through the c face, can be resolved into four Gaussian shaped absorption bands whose peak energies and full widths are 6.72, 1.62; 4.81, 0.88; 3.91. 1.12; and 2.47, 0.72 eV. The 6.72 band lies at the “band-gap” or “edge” and could represent either a shift in the edge or the superposition of one or more bands on the edge. The other bands are, most likely, defect related color centers or trapped molecular species. The coloring contains a small unstable component. at most 10%, consisting of these bands and an additional one at 5.78 eV, width 0.35 eV, which has a negligible effect on coloring kinetic determinations. The color-centers vs. dose curves for the bands at 6.72 and 2.47 eV are linear. The curves for the 4.8...
Wave optics simulation for beams with spatially varying coherence properties

In this work we propose a numerical wave optics approach for simulating the propagation of a beam with spatially varying coherence properties. The concept involves the development of a random screen with spatially varying correlation (SVC) properties that is implemented in the source plane. Three scenarios with different SVC effects are presented and a large sequence of screen realizations is applied and the intensity results after propagation are averaged to yield the partially coherent result. This approach allows the propagation characteristics of a wide range of beam types to be evaluated. The simulation results demonstrate that beams with SVC properties can obtain unusual intensity distribution, which might not be achieved with more conventional beams such as the Gaussian Schell-model beam.
Intelligent autonomy for small throwable land robots

DARPA's Tactical Mobile Robot program includes a Throwable Robot (Throwbot) designed to be thrown into buildings, then teleoperated for surveillance purposes. Use by ground troops imposes significant size and weight limits, as does the requirement that it survive ballistic delivery. The current program stresses the state of the art in robotics and packaging, but further challenges exist. Future Throwbots would benefit from significant increases in autonomy, to deal with RF communication difficulties in buildings and to allow simultaneous operation of multiple vehicles by one person. This paper describes both currently planned and advanced autonomous capabilities.
A note on approximations to discrete probability distributions

An iterative method is presented which gives an optimum approximationto the joint probability distribution of a set of binary variables given the joint probability distributions of any subsets of the variables (any set of component distributions). The most significant feature of this approximation procedure is that there is no limitation to the number or type of component distributions that can be employed. Each step of the iteration gives an improved approximation, and the procedure converges to give an approximation that is the minimum information (i.e. maximum entropy) extension of the component distributions employed.
Strain-induced suppression of weak localization in CVD-grown graphene

We investigate the magnetic-field- and temperature-dependent transport properties of CVD-grown graphene transferred to a flexible substrate (Kapton) and subjected to externally applied strain. In zero magnetic field, a logarithmic temperature-dependent conductivity correction, resulting from strong electron‐electron interaction, becomes weaker with the application of strains as large as 0.6% because of an increased rate of chiral-symmetry-breaking scattering. With the application of a perpendicular magnetic field, we also observe positive magnetoconductance at low temperature (TD 5 K) due to weak localization. This magnetoconductance is suppressed with increasing strain, concomitant with a rapid decrease of the intervalley scattering rate ( 1 i ). Our results are in good agreement with theoretical expectations and are consistent with a strain-induced decoupling between graphene and its underlying Kapton substrate. (Some figures may appear in colour only in the online journal)
Elastic constants versus melting temperature in metals

Examen detaille des relations empiriques existant entre les constantes elastiques et la temperature de fusion de metaux afin de determiner le domaine dans lequel ils peuvent etre utilises. Importance des valeurs de limite de solubilite des alliages
Hepatosplenic T-cell lymphoma.

![Figure][1] A 30-year-old man with an unremarkable medical history presented with fever, anemia, and thrombocytopenia, along with hepatosplenomegaly, for >1 month. Laboratory findings for infectious etiology were nondiagnostic. He underwent surgical resection for splenomegaly. The spleen
Design and performance calculations for a Ka-band CHI wiggler ubitron amplifier

Abstract Design and performance calculations for a coaxial hybrid iron (CHI) wiggler free-electron laser configuration are presented. The capability of generating high fields at short periods, as well as good beam focusing properties, make it a desirable configuration for high power coherent radiation sources in relatively compact systems. In addition to a description of the geometry, numerical calculations detailing the magnetostatic wiggler fields, the beam dynamics, and the interaction of the beam with the electromagnetic waves in the K a -band (26–40 GHz) will be presented. Key considerations for the experimental design will be outlined and discussed.
Liquid scintillation counting with glass fiber paper

Abstract The following conclusions appear warranted: Radioactivity is linearly proportional to the number of disks (up to 25) added to the counting vial over a range of 100 to 40,000 cpm. This relationship seems to hold for both lipid-soluble and water-soluble compounds. Glass fiber paper has a 60–70% higher counting efficiency than cellulose paper. The specific activity can be calculated by using the guide strip for determination of the amount of cholesterol and cholesterol esters; and, by using this data as well as the counts, one can calculate the specific activity of these compounds.
The effect of oscillatory loads on the bearing capacity of floating ice covers

Abstract Parked vehicles with running engines, or motor driven machinery, subject an ice cover to a static load and to a relatively small oscillatory force, that is caused by the moving parts. Since for the driving frequencies in question the dominant feature is fatigue of the ice cover, while it is undergoing nonelastic time-dependent deflections, an experimental program was initiated to study this phenomenon by running a series of tests in one of the cold rooms at CRREL. An electronically driven shaker placed on the ice cover was used to simulate the dynamic case. A loading device of the same weight and base shape was used as a static control in the tests. Each test consisted of placing these two objects on an ice cover and recording how their vertical displacements vary with time, for a fixed driving frequency of the shaker. A comparison of these two curves established the effect of the oscillating force component. Eight tests were conducted. It was found that for urea ice covers and driving frequencies of 1, 10 and 30 Hz (60, 600, and 1800 rpm) the vibrating shaker increased the vertical downward displacements and substantially decreased the time to breakthrough.
Transcriptome profiling of Set5 and Set1 methyltransferases: Tools for visualization of gene expression.

Cells regulate transcription by coordinating the activities of multiple histone modifying complexes. We recently identified the yeast histone H4 methyltransferase Set5 and discovered functional overlap with the histone H3 methyltransferase Set1 in gene expression. Specifically, using next-generation RNA sequencing (RNA-Seq), we found that Set5 and Set1 function synergistically to regulate specific transcriptional programs at subtelomeres and transposable elements [1]. Here we provide a comprehensive description of the methodology and analysis tools corresponding to the data deposited in NCBI's Gene Expression Omnibus (GEO) under the accession number GSE52086. This data complements the experimental methods described in Mas Martin G et al., 2014, and provides the means to explore the cooperative functions of histone H3 and H4 methyltransferases in the regulation of transcription. Furthermore, a fully annotated R code is included to enable researchers to use the following computational tools: comparison of significant differential expression (SDE) profiles; gene ontology enrichment of SDE; and enrichment of SDE relative to chromosomal features, such as centromeres, telomeres, and transposable elements. Overall, we present a bioinformatics platform that can be generally implemented for similar analyses with different datasets and in different organisms.
We Shall Be All: A History of the Industrial Workers of the World

A succinct rendition of Dubofsky's classic and massive history of the IWW, this edition brings the essence of the colorful story of the Industrial Workers of the World to a new generation.
Group Molting and Other Lifeways of a Solitary Hunter, Apateticus bracteatus (Hemiptera: Pentatomidae)

Nymphs of the predaceous stinkbug Apateticus bracteatus hunt singly in goldenrod ( Solidago spp.) stands near Ithaca, N. Y., but recongregate in groups to molt. Molting occurs asynchronously during a period of 24–48 h, with individuals leaving the group a few hours following their molt. 2nd instars form dense clusters of 16–50 individuals, but groups become smaller as the nymphs grow older. Nymphs mature in this habitat on a diet of larvae of Trirhabda virgata and T. borealis (Chrysomelidae). The lifeways of A. bracteatus appear specialized to exploit sluggish prey developing in large number during early summer, a combination of traits exhibited by Trirhabda .
Summary of the 12th international symposium on recent advances in stem cell transplantation.

Conference Venue: Kommunikationszentrum, German Cancer Research Center, Heidelberg, Germany, 22–24 April, 2004 This annual symposium, held alternately in San Diego and Heidelberg, has remained a forum for exchange of innovative ideas among scientists and clinicians from academic institutions as well as from the biomedical industry. As we initiated this symposium at the University of California, San Diego, in March 1992, the clinical use of progenitor cells derived from peripheral blood instead of the marrow was seen with skepticism and regarded as experimental. In the meantime, the role of blood-derived progenitor cells is well established. We have witnessed how stem cell research has evolved and how hematopoietic cell transplantation have become standard therapy for many types of malignancy and hereditary diseases. Above all, stem cells from the bone marrow have learned new tricks! Other than giving rise to blood and immunocompetent cells, they might possess far wider differentiation potentials than previously thought. Hematopoietic stem cells (HSC), mesenchymal stem cells (MSC), or multipotent adult progenitor cells (MAPC), all derived from the bone marrow, might one day represent a valuable alternative source of pluripotent stem cells for regenerative medicine. Given the dynamic development in stem cell research, the main themes of the symposium were focused on the regenerative potentials of adult and embryonic stem cells, in addition to the clinical achievements of blood stem cell transplantation. After the welcome addresses by Professor Klaus Pate, City Council of Heidelberg and Chief Executive Officer, Technology Park, Heidelberg, by Professor Hans-Gunther Sonntag, Dean, Medical School of the University of Heidelberg, and by Anthony D. Ho, Professor Ludwig Siep delivered a special lecture on the ethical problems of stem cell research and stem cell transplantation. He discussed the different meanings of ethics and sketched a map of the ethical
The NO-cGMP-PKG Signaling Pathway Coordinately Regulates ERK and ERK-Driven Gene Expression at Pre- and Postsynaptic Sites Following LTP-Inducing Stimulation of Thalamo-Amygdala Synapses

Long-term potentiation (LTP) at thalamic input synapses to the lateral nucleus of the amygdala (LA) has been proposed as a cellular mechanism of the formation of auditory fear memories. We have previously shown that signaling via ERK/MAPK in both the LA and the medial division of the medial geniculate nucleus/posterior intralaminar nucleus (MGm/PIN) is critical for LTP at thalamo-LA synapses. Here, we show that LTP-inducing stimulation of thalamo-LA inputs regulates the activation of ERK and the expression of ERK-driven immediate early genes (IEGs) in both the LA and MGm/PIN. Further, we show that pharmacological blockade of NMDAR-driven synaptic plasticity, NOS activation, or PKG signaling in the LA significantly impairs high-frequency stimulation-(HFS-) induced ERK activation and IEG expression in both regions, while blockade of extracellular NO signaling in the LA impairs HFS-induced ERK activation and IEG expression exclusively in the MGm/PIN. These findings suggest that NMDAR-driven synaptic plasticity and NO-cGMP-PKG signaling within the LA coordinately regulate ERK-driven gene expression in both the LA and the MGm/PIN following LTP induction at thalamo-LA synapses, and that synaptic plasticity in the LA promotes ERK-driven transcription in MGm/PIN neurons via NO-driven “retrograde signaling”.
Extreme Ultraviolet Absorption by Lithium Fluoride

A study was made to determine the absolute value of the absorption coefficient for lithium fluoride between 10 and 110 ev. The first exciton level in the fundamental absorption was found to be at 12.9 ev. Absorption structure attributed to the fluorine $2s$ electrons and lithium $1s$ electrons was observed. The energy band gap was estimated to be less than 14 ev. The absorption structure associated with the Li $K$ electrons was found at energies corresponding to transitions by the $2s$ electrons of the free ${\mathrm{Li}}^{+}$ ion. A duplication of this structure at a higher energy suggested the possibility that a multiple process was involved in the photon absorption.
Photocrosslinking of 5-Iodouracil-Substituted RNA and DNA to Proteins

5-Iodouracil-substituted RNA and DNA were crosslinked regiospecifically to associated proteins in yields of 70 to 94% of bound nucleic acid. Irradiation of the iodouracil chromophore with monochromatic, long-wavelength ultraviolet radiation (325 nanometers) eliminates excitation of other nucleic acid and protein chromophores. The combination of high crosslinking yields, excellent specificity, and elimination of photodamage to other chromophores represents an important advance toward the precise identification of contacts in nucleoprotein complexes.
New pseudoternary line code for high-speed twisted pair data links

Regulated mark inversion (RMI) is a new pseudoternary line code which minimises high-frequency spectral components in a similar way to the FDDI TP-PMD MLT3 code, and yet also has a bounded running digital sum. The code has significantly lower DC content than standard MLT3, and a lower high-frequency content than run-length-limited MLT3 codes.
The future of scientific drilling in Antarctic waters

Over the past twenty years, nine legs of the Ocean Drilling Programme (ODP) and its predecessor the Deep Sea Drilling Project have been conducted at high southern latitudes (>45°S). Only four have taken place near the margins of the Antarctic continent (>60°S), the last off the Amery Ice Shelf in 1988. At present, JOIDES Resolution is drilling on the Chile Rise-Chile Trench triple junction (46°S), but she will return to lower latitudes at the end of this leg (#141). The Planning Committee of ODP has already approved a schedule that precludes a return to the Antarctic prior to the 1994–95 austral summer at the earliest. Few proposals for Antarctic drilling have even been submitted in recent years; none has received high ranking. This should be a matter of considerable concern to the Antarctic earth sciences community. The JOIDES Resolution is an international asset with a unique sampling capability but the lifetime of the ODP may not extend beyond 1998.
Feasibility of an automated telephone survey to enable prospective monitoring of subjects whose confidentiality is paramount: a four-week cohort study of partner violence recurrence after Emergency Department discharge.

A goal in intimate partner violence (IPV) research is to identify victims when they are treated in a hospital Emergency Department (ED) and predict which patients will sustain abuse again after discharge, so interventions can be targeted. Following patients to determine those prognostic factors is difficult, however, especially to study IPV given the risk to be assaulted if their partner learns of their participation. We assessed the feasibility of an automated telephone survey and a wireless incentive delivery system to follow ED patients after discharge, enabling detection of IPV recurrence. A four-week prospective cohort pilot study was conducted at an urban academic medical center ED in the U.S. Thirty patient subjects (24 women, 6 men; 18–54 years) who had sustained IPV in the past six months, 12 of whom presented for an acute IPV-related condition, were interviewed in the ED and were asked to report weekly for four weeks after discharge to a toll-free, password protected telephone survey, and answer recorded questions using the telephone keypad. A $10 convenience store debit card was provided as an incentive, and was electronically recharged with $10 for each weekly report, with a $20 bonus for making all four reports. Twenty-two of 30 subjects (73.3%) made at least one report to the telephone survey during the four weeks following discharge; 14 of the 30 subjects (46.7%) made all four weekly reports. Each time the telephone survey was accessed, the subject completed all questions (i.e., no mid-survey break-offs). Eight months after follow-up ended, almost all debit cards (86.7%) had been used to make purchases. Approximately three of every four subjects participated in follow-up after ED discharge, and approximately two of every four subjects completed all follow-up reports, suggesting the method of an automated telephone survey and wireless incentive delivery system makes it feasible to study IPV prospectively among discharged patients. That finding, along with evidence that IPV recurrence risk is high, suggests the protocol tested is warranted for use conducting full-scale studies of IPV. The protocol could benefit efforts to study other outcomes, especially when patient confidentiality is paramount for their safety.
The metabolic response to ingested glycine

Background: The metabolic effects of dietary protein are complex. In persons with type 2 diabetes, protein ingestion results in little or no increase in plasma glucose concentrations but a stimulation of insulin and glucagon secretion. Furthermore, when protein is ingested with glucose, a synergistic effect on insulin secretion is observed. The most potent protein is gelatin, which consists of 30% glycine residues. Objective: The objective of the present study was to determine whether glycine per se stimulates insulin secretion or reduces the glucose response when ingested with glucose. Design: Nine healthy subjects were tested on 4 separate occasions. Plasma glucose, insulin, glucagon, and glycine concentrations were measured at various times during a 2-h period after the ingestion of 1 mmol glycine/kg lean body mass, 25 g glucose, 1 mmol glycine/kg lean body mass + 25 g glucose, or water only, given in random order. Results: Plasma concentrations of glycine and glucagon were elevated after the ingestion of glycine, as expected. The serum insulin concentration also was slightly elevated after the ingestion of glycine alone. When glycine was ingested with glucose, the plasma glucose area response was attenuated by > 50% compared with the response after the ingestion of glucose alone. The dynamics of the insulin response after the ingestion of glycine plus glucose were modestly different from those after the ingestion of glucose alone, but the area response was not significantly different. Conclusion: The data are compatible with the hypothesis that oral glycine stimulates the secretion of a gut hormone that potentiates the effect of insulin on glucose removal from the circulation. Am J Clin Nutr 2002;76:1302‐7.
Impact of federal compliance reviews of trucking companies in reducing highway truck crashes.

Abstract Background The compliance review (CR) is a federal program monitoring motor carrier safety performance and regulatory compliance. This study sought to assess the impact of CRs on reviewed trucking companies in reducing truck crashes. Methods Data was from the Motor Carrier Management Information System. Study subjects were trucking companies established during 1990–1995, had at least one truck, and remained active until April 2004. Truck crash data of these companies was examined from 1996 to 2003. The crash rates in 2003 and annual percentage changes in number of crashes were computed. Analyses were stratified by company size, organization, operation classification, and safety rating. Results Companies that received CRs had a higher crash rate than never-reviewed companies. Reviewed companies experienced a 39–15% reduction in number of crashes in the year the CR was performed. The reduction in crashes was observed in all reviewed companies regardless of company size, operation classification, type of organization, or safety rating. The reduction in crashes was sustained for at least 7 years after CRs. Discussion The study results were controlled for the year in which CRs were performed, crash trend, and CR selection bias. However, further studies, especially a randomized prospective longitudinal study, are needed to overcome the limitations that are associated with an observation study.
Looking Inward Shifting Attention Within Working Memory Representations Alters Emotional Responses

Selective attention plays a fundamental role in emotion regulation. To date, research has examined individuals' use of selective attention to regulate emotional responses during stimulus presentation. In the present study, we examined whether selective attention can be used to regulate emotional responses during a poststimulus period when representations are active within working memory (WM). On each trial, participants viewed either a negative or a neutral image. After the offset of the image, they maintained a representation of it in WM and were cued to focus their attention on either neutral or arousing aspects of that representation. Results showed that, relative to focusing on an arousing portion of a negative-image representation within WM, focusing on a neutral portion of the representation reduced both self-reported negative emotion and the late positive potential, a robust neural measure of emotional reactivity. These data suggest that selective attention can alter emotional responses arising from affective representations active within WM.
Neurochemical and neurobehavioral effects of repeated gestational exposure to chlorpyrifos in maternal and developing rats

Acute exposure to the organophosphate pesticide chlorpyrifos (CPF) on gestation day 12 (GD12, 200 mg/kg/ml, SC) causes extensive neurochemical changes in maternal brain but lesser changes in fetal brain. In the present study, we examined the relative neurotoxicity of repeated, lower-level CPF exposures during gestation in rats. Pregnant Sprague-Dawley rats were exposed to CPF (6.25, 12.5, or 25 mg/kg per day, SC) from GD12-19 and sampled at either GD16, GD20, or postnatal day 3 (PND3) for measurement of various maternal and developmental neurochemical markers. In contrast to the high acute dose exposure, no maternal toxicity was noted with repeated lower-level dosing. Extensive acetylcholinesterase (AChE) inhibition (83-90%) was noted in maternal brain at all three time points following repeated exposures (25 mg/kg). Higher AChE inhibition (58%) was noted in fetal brain at GD20 compared to 19-25% on PND3 in treated pups cross-fostered to control dams and in control pups cross-fostered to treated dams following repeated exposures (25 mg/kg per day). Whereas similar reductions in brain muscarinic receptor binding were noted at GD20 and PND3 in dams and developing brain between acute and repeated dosing regimens, greater changes in [3H]CD and [3H]cytisine binding were evident following repeated exposures. Righting reflex and cliff avoidance tests were markedly altered following repeated exposures. The results suggest that lower-level repeated exposures to CPF cause extensive neurochemical and neurobehavioral changes in developing rats in the absence of maternal toxicity.
Phase noise in low bit rate transportable Ka band satellite terminals

The development of low bit rate terminals for use with wide bandwidth Ka band transponders, such as ACTS, has forced a reconsideration of phase noise and how it effects low bit rate systems. In this paper we initially calculate the cumulative effect of the phase noise contributions from the oscillators in the ground based transmitter, satellite transponder, and the ground based receiver. We will discuss the cases where the carrier power-to-phase noise power ratio is much larger and much smaller than the carrier power-to-noise/interference power ratio. We extend our results to the case of non-white phase noise spectrum and compare with actual oscillator spectra. We also will discuss complications arising from the fact that one cannot change the phase noise characteristics of the spacecraft. We conclude by illustrating how these analyses can be used to predict the increase in error probability due to phase noise. >