cssi/SciSciGPT-SciSciNet huggingface dataset:
Vacuum insulator studies for the dielectric wall accelerator

As part of our ongoing development of the dielectric wall accelerator, we are studying the performance of multilayer high-gradient insulators. These vacuum insulating structures are composed of thin, alternating layers of metal and dielectric, and have been shown to withstand higher gradients than conventional vacuum insulator materials. This paper describes these structures and presents some of our recent results.
Sampling on locally defined principal manifolds

We start with a locally defined principal curve definition for a given probability density function (pdf) and define a pairwise manifold score based on local derivatives of the pdf. Proposed manifold score can be used to check if data pairs lie on the same manifold. We use this score to i) cluster nonlinear manifolds having irregular shapes, and ii) (down)sample a selected principal curve with sufficient accuracy sparsely. Our goal is to provide a heuristic-free formulation for principal graph generation and curve parametrization in order to form a basis for a principled principal manifold unwrapping method.
Note 27--Morphostratigraphic Units in Pleistocene Stratigraphy: STRATIGRAPHIC COMMISSION

A morphostratigraphic unit is a body of rock that is identified primarily from the surface form it displays; it may or may not be distinctive lithologically from contiguous units; and it may or may not transgress time throughout its extent. It may or may not represent a climatic episode that can be traced widely, as for a geologic-climate unit. Morphostratigraphic units in glaciated areas are moraines, outwash aprons, and associated forms, whereas the term also can be applied to alluvial terrace deposits, alluvial fans, lake plains, beach ridges, pediment veneers, and other such deposits. These units serve a need long apparent to those working in the bordering fields of geomorphology and stratigraphy, and furnish a formal category that permits many surficial deposits to be treated as legitimate stratigraphic entities while allowing the full use of geomorphic criteria.
A Theory of Shopping/ Shopping, Place, and Identity

Theory of Shopping. Daniel Miller. Ithaca, NY: Cornell University Press, 1998. ix. 180 pp., notes, bibliography, index. Shopping, Place, and Identity. Daniel Miller. Peter Jackson. Nigel Thrift. Beverly Holbrook. and Michael Rowlands. New York: Routledge, 1998. xi. 214 pp., notes, bibliography, index.
Migrant Wives and Tirailleurs Senegalais: Questioning Volition in the Nineteenth Century

At the end of the nineteenth century, West African women partnered with tirailleurs senegalais and traveled to French Equatorial Africa and Madagascar. By funding these women’s migrations, the French colonial military implicitly recognized the unions between women and soldiers as marriage. Significantly, many of these unions had not occurred in accordance with indigenous or French normative practices. Couples had paired during large-scale conflicts involving Mamadou Lamine, Samori Toure, and the French military. Many Tirailleurs senegalais and their wives were of low social status due to slave origins, which made them vulnerable to social upheavals created by these conflicts. However, without the socially-imposed constraints of their communities, West Africans of low status had greater ability to partner according to their desire. This paper examines volition in marriages between colonial soldiers and West African women, as well as in their subsequent migrations to the frontiers of French Empire. In doing so, I will unpack how social rank, marital status and gender coalesced to impose constraints upon women’s volition in migrating with colonial soldiers. I will also examine how the presence of West African military wives imposed limits on the French military’s coercive power over tirailleurs senegalais.
The Measurement of Intelligence

Publisher Summary This chapter discusses the Stanford-Binet Intelligence Scale (Binet), the Wechsler Intelligence Scale for Children (WISC), and the Wechsler Adult Intelligence Scale (WAIS). The WISC is essentially a revision and restandardization of Form II of the Wechsler-Bellevue Intelligence Scale and the WAIS bears a similar relationship to Form I of that test. The WISC and the WAIS have a number of features in common. The WISC contains 12 subtests divided into two scales. The WAIS contains 11 subtests also divided into two scales. The composition of the verbal scale is the same as for the WISC; on the performance scale, coding is replaced by digit symbol and mazes are omitted. To find IQ on both the WISC and the WAIS, the raw score on each subtest is first translated to a scaled score with a mean of 10 and an SD of 3. On the WISC, tables for this purpose are provided for ages 5 to 16. On the WAIS, the corresponding table is based on the performance of subjects between the ages of 20 and 34 who generally obtained the highest scores. On both the tests, the sum of the scaled scores on the verbal, performance, and full scales are then converted to IQs with the aid of additional tables.
Software Defined Radio implementation of DS-CDMA in inter-satellite communications for small satellites

In this paper, we study the problem of multi-user inter-satellite communications in a network of small satellites and design and implement of an optimum CDMA-based multiple access communication using Software Defined Radios. Inter-satellite links (ISL) enable small satellites to exchange information and share resources while reducing the traffic load to the ground. The ISL assist in performing advanced functions including distributed processing and autonomous applications. By utilizing the ISL in maintaining the relative distance between the satellites, navigation, and positioning accuracy is improved greatly. The ideology proposed here is to implement remote modifications in inter-satellite communication after launch using Software Defined Radios (SDRs), while accommodating an adaptive autonomous small satellite network. Remote upgrades from the ground as well as the potential to accommodate new applications and future services without hardware changes is very promising. Software defined radio-based implementation of an ISL can assist in enabling an adaptive and reconfigurable communication system, which can achieve higher data rates and modification of frequencies. In this paper, we designed and implemented a multi-user inter-satellite communication network using SDRs, where Code Division Multiple Access (CDMA) technique is utilized to manage the multiple access to shared communication channel among the satellites. This research is the first work to study and implement the utilization of SDRs for inter-satellite communications in small satellite systems.
Intelligent traffic light controller design using FPGA digest of technical papers

This paper is to design an intelligent traffic light controller using Spartan 3E FPGA (Field Programmable Gate Array) with five-phase traffic control. It adapts to the traffic How for the peak and off-peak traffic time of a day, as well as the traffic patterns during the vacation time.
Enhanced contactless dielectrophoresis enrichment and isolation platform via cell- scale microstructures

We designed a new microfluidic device that uses pillars on the same order as the diameter of a cell (20 μm) to isolate and enrich rare cell samples from background. These cell-scale microstructures improve viability, trapping efficiency, and throughput while reducing pearl chaining. The area where cells trap on each pillar is small, such that only one or two cells trap while fluid flow carries away excess cells. We employed contactless dielectrophoresis in which a thin PDMS membrane separates the cell suspension from the electrodes, improving cell viability for off-chip collection and analysis. We compared viability and trapping efficiency of a highly aggressive Mouse Ovarian Surface Epithelial (MOSE) cell line in this 20 μm pillar device to measurements in an earlier device with the same layout but pillars of 100 μm diameter. We found that MOSE cells in the new device with 20 μm pillars had higher viability at 350 VRMS, 30 kHz, and 1.2 ml/h (control 77%, untrapped 71%, trapped 81%) than in the previous generation device (untrapped 47%, trapped 42%). The new device can trap up to 6 times more cells under the same conditions. Our new device can sort cells with a high flow rate of 2.2 ml/h and throughput of a few million cells per hour while maintaining a viable population of cells for off-chip analysis. By using the device to separate subpopulations of tumor cells while maintaining their viability at large sample sizes, this technology can be used in developing personalized treatments that target the most aggressive cancerous cells.
Pairing interaction near a nematic quantum critical point of a three-band CuO 2 model

In this paper, we calculate the pairing interaction and the k dependence of the gap function associated with the nematic charge fluctuations of a CuO2 model.We find that the nematic pairing interaction is attractive for small momentum transfer and that it gives rise to d-wave pairing. Finally, as the doping p approaches a quantum critical point, the strength of this pairing increases and higher d-wave harmonics contribute to the k dependence of the superconducting gap function, reflecting the longer range nature of the nematic fluctuations.
Conditional Residence for Unauthorised Immigrant Parents

In this article, I argue that states have a long-term public policy interest in applying the best interests of the child standard that they use for domestic child welfare determinations in immigration cases that involve deportable non-citizen parents. But I also recognise that the interests of existing citizens in effective immigration regulation and enforcement need to be taken into consideration. The burden lies with parents who entered and continued to reside without authorisation in a country to show that their right to remain is of benefit to existing citizens. This means that unauthorised immigrant parents should only be given conditional permission to stay in their children’s country of long-term residence to raise them. Otherwise deportable parents should not be immediately legalised outright. Rather, they should be held to account for discharging their duty to their children in the same manner as immigrants whose residence is conditional for other reasons.
EFFECT OF FABRIC ANISOTROPY ON DYNAMIC SHEAR MODULUS IN K_0 CONDITION

Dynamic shear modulus is a critical factor for sand in engineering practice. In order to evaluate the effects of fabric anisotropy on dynamic shear modulus,the measurement of wave velocity by bender element technique is conducted. The special container is manufactured to prepare the model with deposition angles of 0°, ±45°and 90°. The Toyoura sand specimens with specified deposition angles are tested in loading and unloading conditions. The results show that the sand sample prepare in the deposition angle of 90° has the largest shear modulus in horizontal and vertical directions. It is found that in unloading condition,specimens with different deposition angles show different responses for stress history,and response of sand sample with deposition angle of 90° is most obvious,which verify that influence of deposition angle on small strain shear stiffness of sand is very significant. Based on the results,a micromechanical stress-strain model is validated,which could show the influences of fabric anisotropy,stress condition and particle contact characteristics on dynamic shear modulus reasonably.
Production and Consumption in the Archaeological Record: A Hohokam Example

ABSTRACTAnalysis of botanical materials from archaeological sites provides basic data in the form of quantified resource tabulations. Although biases are acknowledged in the formation of this record, it is usually assumed that sufficiently large samples provide insight into representative resources for a provenience. It is a further inferential leap to equate recovered resources with either production or consumption, or with local or extra-local acquisition. We must attempt to distinquish evidence of production from consumption in the archaeological record if we are to effectively investigate problems such as resource specialization, trade, and redistribution. These distinctions can be approached through direct evidence of production and consumption activities and through circumstantial and comparative argument. Illustrations are drawn from early Classic period Hohokam contexts in the Tucson Basin.
Antibacterial activity of fractions from three Chumash medicinal plant extracts and in vitro inhibition of the enzyme enoyl reductase by the flavonoid jaceosidin

We have investigated the in vitro antibacterial bioactivity of dichloromethane-soluble fractions of Artemisia californica, Trichostema lanatum, Salvia apiana, Sambucus nigra ssp. cerulea and Quercus agrifolia Nee against a ΔtolC mutant strain of Escherichia coli. These plants are traditional medicinal plants of the Chumash American Indians of Southern California. Bioassay-guided fractionation led to the isolation of three flavonoid compounds from A. californica: jaceosidin (1), jaceidin (2), and chrysoplenol B (3). Compounds 1 and 2 exhibited antibacterial activity against E. coli ΔtolC in liquid cultures. The in vitro activity of 1 against the enoyl reductase enzyme (FabI) was measured using a spectrophotometric assay and found to completely inhibit FabI activity at a concentration of 100 μM. However, comparison of minimum inhibitory concentration values for 1–3 against E. coli ΔtolC and an equivalent strain containing a plasmid constitutively expressing fabI did not reveal any selectivity for FabI in vivo.
Career Advancement in a Research Environment

Brrokhaven National Laboratory (BNL) was the first and only national laboratory to participate in the FORWARD to Professorship program. Located in Upton, NY, BNL is a Department of Energy (DoE)–funded laboratory created to “advance the mission of the U.S. Department of Energy’s Office of Science through the study of nuclear and particle physics to gain a deeper understanding of matter, energy, space, and time.” Since the main function of the lab is scientific research using large, world-class facilities rather than teaching, workshop topics addressed the issues specific to career paths in this setting. Another unique aspect of this program was that it was a joint effort with Stony Brook University (SBU), in Stony Brook, NY. While this partnership worked well, several workshops addressed the differences between an academic institution and a national laboratory.
Voronovskaya Type Asymptotic Expansions for Multivariate Generalized Discrete Singular Operators

Here we give asymptotic expansions including simultaneous ones, for the multivariate generalized discrete versions of unitary Picard, Gauss-Weierstrass, and Poisson-Cauchy type singular operators. These are Voronovskaya type expansions and they are connected to the approximation properties of these operators.
Spectral diffusion of single impurity centers in crystals

Single-molecule detection and spectroscopy in solids has the potential for direct observation of the microscopic physics and chemistry of defects without multicenter averaging. Initial observations of the optical absorption spectra of a single pentacene molecule in p-terphenyl crystals achieved signal-to-noise ratios (SNR's) of 3-5 in a 1-Hz bandwidth and required intensities at the sample above the saturation intensity. Careful noise analysis of our detectors showed that little improvement in SNR could be expected with an absorption technique unless simple and reliable sources of squeezed light were available. Recent advances in fluorescence- excitation spectroscopy have removed this SNR limitation.3
Teaching Our Teachers: Trans* and Gender Education in Teacher Preparation and Professional Development

With a book focusing on teaching and affirming trans* and gender creative youth, it is critical to discuss not only the experiences of these students in schools and specific practices teachers can employ to make school spaces more inclusive for trans* and gender non-conforming students, but to also include a discussion on the preparation of teachers to work with this population. Brant presents the data from two studies measuring preservice and inservice teachers’ perceived self-efficacy in working with and working for trans* and gender creative youth. From this data she makes recommendations about the ways in which teacher educators can apply a Queer Literacy Framework as a part of a teacher preparation program.
Portable Nanopore Sequencing for Viral Surveillance.

The recent Nature article (1) entitled, “Real-Time, Portable Genome Sequencing for Ebola Surveillance,” reports nanopore sequencing of the Ebola virus from 142 subjects near the end of the outbreak in West Africa from March to October 2015. The nanopore sequencer (MinION, Oxford Nanopore Technologies) has a mass of 87 g and plugs into a laptop computer by way of a USB 3.0 interface and cable. The consumable flow cell has up to 512 channels available for sequencing, each of which can simultaneously read single strands of DNA and their ligated complementary strands as “2D” reads, providing correlated data on both strands of DNA. The nanopores are typically made up of proteins like α-hemolysin that are pore-forming bacterial toxins embedded in an electrically insulating membrane. A voltage between the 2 sides of the membrane attracts DNA to the pore in an electrolyte solution. The DNA is captured by a polymerase near the pore that paces the rate of transport to 30–280 bases/s. The passage of single-stranded DNA affects the pore current, generating electrical “squiggle signals” that are sequence-specific. In simple terms, this is the Coulter principle applied to molecules rather than cells. In half of the cases, sufficient reads (25 2D reads for each amplicon) were obtained in <1 h of instrument time with a mean passing rate of 36.3%. The mean read rate was 138 amplicons/min, and in some cases, only 15 min of sequencing was required. Custom offline acquisition software was provided by the company so that Internet communication was not initially required. Nanopore sequencing is conceptually elegant and data acquisition is fast. However… Before sequencing, sample transport and preparation are required. To prevent delays of air transport of samples, a portable 50-kg laboratory was transported in airline luggage to Guinea. As samples became available locally, they were transported …
Density and Egg Parasitism of Stink Bugs (Hemiptera: Pentatomidae) in Elderberry and Dispersal Into Crops

Chinavia hilaris (Say), Euschistus servus (Say), Euschistus tristigmus (Say), and Thyanta custator custator (F.) (Hemiptera: Pentatomidae) are serious pests of crops in the southeastern United States but little is known concerning their dispersal from noncrop hosts in woodlands into crops. This 2-yr study was conducted to investigate whether elderberry [ Sambucus nigra subsp. canadensis (L.) R. Bolli] in woodlands serves as a source of stink bugs dispersing into adjacent crops and to examine parasitism of C. hilaris and E. servus eggs on this plant. Elderberry was a reproductive host for each of the four stink bug species; females oviposited on plants with subsequent nymphs feeding on elderberry and developing into adults. Anastatus mirabilis (Walsh & Riley) (Hymenoptera: Eupelmidae), Anastatus reduvii (Howard), and Trissolcus edessae Fouts (Hymenoptera: Scelionidae) were prevalent egg parasitoids of C. hilaris but A. reduvii was the prevalent parasitoid of E. servus . Newly developed stink bug adults were first detected on elderberry around mid-July. Then in late July and early August, as elderberry fruit senesced and cotton bolls became available, stink bugs began dispersing from elderberry into cotton based on recapture of stink bugs on cotton that had previously been marked on elderberry. In addition, in 2015, density of C. hilaris , E. servus , and E. tristigmus was higher in cotton with elderberry than in cotton without it. Over the study, economic threshold was reached for four of seven cotton fields. Elimination of elderberry in woodlands adjacent to cotton may be a viable management tactic for control of stink bugs in cotton.
Computer Science Teaching Knowledge: A Framework and Assessment (Abstract Only)

Educators, researchers, politicians, tech companies, and others continue to advocate for the importance of K-12 students learning computer science in our increasingly tech-driven society. One way school districts in the United States address this growing demand is by allowing teachers certified in other disciplines to lead computer science courses. Summer and weekend professional development opportunities support these educators in developing the expertise needed for effective computer science teaching, but a great portion of their learning to teach computer science will occur through on-the-job experiences. Our four-year NSF EHR grant explores how a job-embedded professional development program that pairs high school teachers with tech industry professionals supports educators in acquiring computer science teaching knowledge. The research presented in this poster focuses on the third year of the study and includes (a) a theoretical component focused on creating a framework to explain on-the-job computer science teaching knowledge development based on case studies with six teachers, and (b) an empirical component focused on the creation and administration of a computer science teaching knowledge assessment. By the time of the SIGCSE symposium, we expect to have pre-test results from the first administration of our teaching knowledge assessment, completed by both high school teachers and their collaborating tech industry professionals. This poster will present our theoretical framework, resultant teaching knowledge assessment with sample items, and analysis of participants' assessment responses and their relationship to specific teaching experiences.
Reproductive history and fracture risk in postmenopausal women in a US national survey.

Estrogen promotes bone health, long-term replacement delaying osteoporosis,1 while sex steroids given for menstrual irregularity to premenopausal women increase bone mass.2 We therefore assessed the relation between reproductive health and fracture risk in postmenopausal women (≥50 years) in the US National Health and Nutrition Examination Survey (NHANES).3 In the 2013–2014 survey, fracture risk as FRAX scores4 was reported in an osteoporosis questionnaire with calculation of the 10-year risk of major hip fracture. We collected data on the age at last menstrual period, last live birth, and first live birth as continuous variables, and documented history of pregnancy …
Modulation of the Immune Response in Critical Illness/Injury

The systemic inflammatory response is elicited in a multitude of clinical scenarios including infection, tissue injury (surgical or traumatic), ischemia-reperfusion, post-cardiopulmonary bypass, as well as autoimmune phenomena. There are many factors capable of modulating the magnitude and quality of the immune response during critical illness/injury. Some factors precede critical illness/injury such as chronic poor nutrition, chronic stress (physiologic and/or psychologic), and underlying infectious disease (chronic and acute). Other factors become important modulators during a critical illness/injury including acute stress, infection, tissue injury, poor nutrition, and pharmacologic agents not usually associated with immunomodulation.
Leydig Cell Structure and Steroidogenic Function

Publisher Summary This chapter reviews the spatial organization of the testosterone biosynthesizing apparatus in the testis. It focuses on the control gained by separating enzymes inter- and intracellularly. The chapter explains that Leydig cell steroidogenic activity is closely correlated with structure. It also discusses the advances in stereology and in vitro perfusion techniques which facilitate the study of Leydig cell structure and function. It presents the results which show that Leydig cell steroidogenic activity is correlated closely with structure, particularly with the surface area of smooth endoplasmic reticulum. The chapter additionally describes the effect of luteinizing hormone (LH) on the number and volume of Leydig cells, and on the surface area of Leydig cell cytoplasmic organelle membranes. Testosterone is derived almost exclusively from Leydig cells. Therefore, one form of regulation of testosterone production is to control Leydig cell division, growth, differentiation, and/or death. This regulatory strategy is used commonly because fetal development and pubertal masculinization are associated with the appearance of morphologically recognizable, steroidogenically active Leydig cells.
The Effect of Irrigative Quality Water by Addition Various Acids of Growth and Wheat Total (Triticum aestivum)

An experiment has been conducted to study the effect of the quality of irrigation water quality and festination with Potassium and KSC in wheat (Triticum aestivum) cv Moelhu growth productivity. Eight treatments were applied ; irrigation with river water , drainage water , river water plus Potassium humate , river water plus KSC , river water plus Potassium humate plus KSC , drainage water plus Potassium humate , drainage water plus KSC , drainage water plus Potassium humate plus KSC . The treatments are put in completely randomized design with three replications . The parameters measured included ; plant height , spike length , total chlorophyll in SPAD , biological yield , grain yield , harwst index and NPK leaves content . The results show outweigh the treatment of river, the added organic matter type Slphoric acid and type Potassium humateas compared with the other proportion like the rate of chlorophyll in the leaves, while not it's significantly different from the treatment by drainage water that added organic matter to both previous properties, but it's significantly different as compared with it by plant height feature . and the drainage water excelled with added two types of organic matter in the character of the length of the tufts compared with the comparison treatment and treatment of river water that the added matter of both two types of organic material that are used in the experiment.
Impact of Ethnicity, Sex, and Socio-Economic Status on the Risk for Heart Failure Readmission: The Importance of Context

Background: Hispanics are a fast-growing minority in the United States and have a high risk for the development of heart failure (HF). Hispanics have higher HF-related hospital readmission rates compared with non-His­panics. However, the risk of readmission in a largely disadvantaged and majority Hispanic population has not been evaluated. Methods: We analyzed data for patients discharged with a principal discharge diagnosis of HF from the University of New Mexico Hospital from 2010–2014. Student t-test and chi-square analysis were used to assess the unadjusted associations between baseline characteristics and 30- day readmission rate. Multivariable logistic regression modeling evaluated the associa­tions between 30-day hospital readmission rate, socio-demographic characteristics, and clinical variables. Results: A total of 1,594 patients were included in our analysis. Mean age (SD) was 63.1 ± 14 and 62.9 ±13.8 (P=.07) for His­panics and non-Hispanics, respectively. Sixty percent of Hispanics had HF with reduced ejection fraction compared with 53.9% of non-Hispanics (P=.012). In unadjusted analysis, Hispanic ethnicity was associated with a two-fold increase in HF readmission rate compared with non-Hispanic ethnicity (OR 2.0, 95% CI 1.5–2.7). In fully adjusted models, Hispanic ethnicity showed an 80% increase in HF readmission rate compared with non-Hispanic ethnicity (OR 1.8, 95% CI 1.2–2.6). Conclusion: Among patients from a socio­economically disadvantaged background living in a Hispanic-majority area, being Hispanic is associated with higher odds of 30-day hospital re-admission after adjusting for demographic, clinical and socioeco­nomic covariates. Our findings show that further research is needed to understand disparities in Hispanic’s heart failure-related outcomes. Ethn Dis. 2018;28(2):99-104; doi:10.18865/ed.28.2.99.
Neutron Detector Systems for Neutron Nuclear Data Measurements

Nuclear data are essential in a wide range of applications including nuclear power reactors, nuclear safety, space radiation effects, medical radiation diagnostics and therapy, radiation effects on semiconductors, passive and active interrogation schemes, radiography, accelerator- driven systems, astrophysics and basic science research. These data are embodied in evaluated data libraries and reaction models and are used in radiation transport codes. The accuracy of the calculations and therefore the credibility of the results depend on the accuracy of the input data. Continuing progress in the quality of these data has led to the present situation where a great variety of effects can be calculated with confidence, with limits being determined often by other considerations such as the representation of the system to be calculated, thermal-hydraulic properties including their time dependence, and so forth. As computer calculations get ever faster and more accurate, however, new demands will be placed on the both on the codes and the input data. Some of the most important data are obtained with neutron detectors. This talk will review the properties of neutron detectors used for nuclear data measurements and the requirements put on them to address the need for more accurate and complete nuclear data. In this review emphasis will be given to detector systems developed and used for nuclear physics and nuclear data measurements with spallation neutron sources at the Los Alamos Neutron Science Center (LANSCE) at the Los Alamos National Laboratory.
Superagonist IL-15-Armed Oncolytic Virus Elicits Potent Antitumor Immunity and Therapy That Are Enhanced with PD-1 Blockade.

Oncolytic immunotherapy is a promising novel therapeutic for cancer, and further preclinical studies may maximize its therapeutic efficacy. In this study, we construct a novel oncolytic vaccinia virus (VV) expressing a superagoinst IL-15, a fusion protein of IL-15 and IL-15Ralpha. This virus, named vvDD-IL15-Rα, possesses similar replication efficiency as the parental virus vvDD yet leads to significantly more regression of the disease and extends the survival of mice bearing MC38 colon or ID8 ovarian cancer. This novel virus elicits potent adaptive antitumor immunity as shown by ELISPOT assays for interferon-gamma-secreting CD8+ T cells and by the rejection of tumor implants upon re-challenge in the mice, which were previously cured by vvDD-IL15-Rα treatment. In vivo cell depletion assays with antibodies showed that this antitumor activity is highly dependent on CD8+ T cells but much less so on CD4+ T cells and NK cells. Finally, the combination of the oncolytic immunotherapy with anti-PD-1 antibody dramatically improves the therapeutic outcome compared to either anti-PD-1 alone or vvDD-IL15-Rα alone. These results demonstrate that the IL-15-IL-15Rα fusion protein-expressing OV elicits potent antitumor immunity, and rational combination with PD-1 blockade leads to dramatic tumor regression and prolongs the survival of mice bearing colon or ovarian cancers.
Concealed Guns on College Campuses: Examining Support for Campus Carry Among Faculty, Staff, and Students

This study examined the factors that influence support for campus carry laws among a sample of approximately 2,700 faculty/administrators, staff, and students at a large, public university in Georg...
Structural Features of Twisted Stacked-Tape Cables With High Lorentz Loads Using Finite Element Analysis

Structural support features for a twisted stacked-tape cable (TSTC) were evaluated through finite element analysis (FEA) to evaluate the mechanical performance of a TSTC surrounded with a rigid copper core and exposed to transverse compression. Annealing of the copper core can occur during the manufacturing process; so, the stress accumulation of the stack was studied as a function of yield strength of the copper, and the results suggested that a lower yield strength copper would result in higher stress accumulation in the tape stack. To ensure adequate support for the cable, two possible solutions were presented: increasing the core diameter or adding a stainless-steel jacket outside the core containing the stack of tapes. Both options resulted in similar reduction in the maximum stress of the tapes. The mechanical stability of a conductor can also be affected by the thickness of the tapes used in the cable. For the same cable dimensions, higher current densities can be obtained using thinner tapes, which however could jeopardize the mechanical integrity of the support. Different tape architectures, varying substrate, and copper stabilizer thicknesses were also studied. Results suggested that for the same amount of current carried by each tape, thinner tapes will experience higher stress. Finally, a full-scale twisted model was developed. A more complex and time-consuming twisted model provides results that are very similar to the simpler untwisted configuration used in this work, justifying its utilization.
ESTIMATING THE ECONOMIC VALUE OF COASTAL WETLANDS: CONCEPTUAL ISSUES AND RESEARCH NEEDS

Estimates of the economic value of coastal wetlands can better establish their social worth and provide an improved focus for debates over wetlands' preservation. This has been recognized by many authors, and several approaches to economic valuation now appear in the literature on wetlands. The most prominent techniques are the transferences of energy flows to monetary equivalents and the estimation of the market value of harvestable species and other direct user services derived from wetlands. The results reported are often based upon approaches which have conceptual weaknesses. However, valid estimates of wetlands' economic values are difficult to obtain at this time due to a dearth of physical and biological data relevant for economic analysis. Cooperative research between physical and economic scientists can begin to provide the necessary information for sound economic analysis. Nonetheless, in the near future we can only expect limited success in establishing the economic value of natural coastal wetlands. Until that time, decisions on use of wetlands must be made under conditions of scientific uncertainty.
Control of Formations with Nonlinear Non-Passive Actuation

This paper considers the problem of cooperatively inducing a group of agents to achieve a rigid formation specified by a subset of interagent distances, by decentralized control: The agents have access to their relative positions with respect to their neighbors and their own velocity. Barring our work in [17], all previous papers have assumed that the actuation dynamics represented by the system relating the agent velocity to the control input is passive. On its part [17] relaxed this assumption to include systems that are linear time invariant (LTI) but not passive. In this paper we extend to nonlinear dynamics, and require that it and its inverse be $\mathcal{L}_{2}$ -stable and have an asymptotically stable zero dynamics. We formulate a control algorithm and prove its local asymptotic stability.
Leukocyte Interferon Production, RNA Synthesis, and PHA Response in Patients With Infectious Mononucleosis

Sequential measurements of in vitro Newcastle disease virus-induced interferon (IF) synthesis, spontaneous RNA synthesis, and PHA-induced blastic transformation were made in leukocytes derived from ten patients with infectious mononucleosis (IM). The median leukocyte IF production on the day of diagnosis was found to be significantly depressed, 35 international units (IU) IF per 2 x 106 leukocytes, in comparison to a median titer of 463 IU after recovery ( p < 0.002) or to a median of 406 IU found in 52 cultures from normal healthy individuals. No spontaneous production of leukocyte IF or circulating serum IF was noted. An increased rate of spontaneous leukocyte RNA synthesis during the first 2 hr of culture was noted in nine of the ten subjects ( p < 0.001). Four of the ten patients showed a markedly defective response to PHA after 96-144 hr in culture. A suggestive, but not statistically significant, correlation was noted between increased spontaneous RNA synthesis, defective late PHA transformation, and defective virus-induced IF production. All defects persisted during the 1-wk study period and were resolved after recovery. We conclude that major temporary alterations occur in several parameters of leukocyte function in IM.
Bony Ingrowth of Coil-Type Open-Architecture Anchors Compared With Screw-Type PEEK Anchors for the Medial Row in Rotator Cuff Repair: A Randomized Controlled Trial.

Purpose To evaluate outcomes of screw-type and coil-type open-architecture suture anchors with respect to bony ingrowth, release of biological markers, and patient-reported outcome measures when used in rotator cuff repair (RCR). Methods Forty patients undergoing arthroscopic RCR for full-thickness rotator cuff tears were enrolled and prospectively randomized to receive a screw-type (19 patients) or coil-type (21 patients) suture anchor for the medial row during repair. All repairs used a transosseous-equivalent configuration with footprint anchors laterally. Marrow elements released during surgery were evaluated for 9 cytokine markers (insulin-like growth factor 1, fibroblast growth factor 2, bone morphogenetic proteins 7 and 2, platelet-derived growth factors AA and BB, epidermal growth factor, transforming growth factor beta1, and vascular endothelial growth factor). Postoperative computed tomography scans were performed at 6 months. Range of motion, strength, and validated patient-reported outcome measures (Simple Shoulder Test, Single Assessment Numeric Evaluation, visual analog scale, and American Shoulder and Elbow Surgeons scores) were gathered before the operation and at 6 months and 1 year postoperatively. Results Bone mineral density surrounding the coil-type anchor was significantly greater than that surrounding the screw-type anchor (P = .005). Bone mineral density values within the coil-type and screw-type anchors were comparable (P = .527); however, a larger amount of total bone mineral mass (in milligrams) was shown within the coil-type anchor owing to its larger volume (P .05). Postoperatively, no statistically significant difference was found between groups for clinical outcome measures at 6 months or 1 year. Retear and complication rates were similar between groups (P > .05). Conclusions Both the coil-type and screw-type anchors can be reliably used for RCR and produce similar clinical outcomes. The coil-type anchor resulted in superior bony growth surrounding the anchor and a larger total bone mineral mass within the anchor owing to its larger volume. Level of Evidence Level II, randomized prospective comparative study.
Criminal Investigation and Canadian National Identity in Murdoch Mysteries

This essay argues that Canadian detective show Murdoch Mysteries uses the legal conflict between Canadian criminal investigation and American foreign policy to shore up an idea of Canadian national identity against an explicitly American other. First, I discuss the character of William Murdoch as a distinct departure from the literary tradition of the nineteenth-century police officer. Second, I show how Murdoch Mysteries attempts to serve as social criticism concerning socio-legal issues still relevant to Canadian society in the present day. Third, I argue that the show’s ongoing depiction of criminal jurisdictional conflict between the Toronto constabulary and Her Majesty’s government in Ottawa reveals anxieties over the present-day American threat to Canadian security and way of life. Finally, I conclude that the repeated narrative contrast between Murdoch’s scientific criminal investigations and federal strategies of American appeasement serves the secondary purpose of displacing domestic social anxieties onto an American other and reifying a Canadian national identity premised on objectivity and the rule of law.
Boundary Stabilization and Disturbance Rejection for Time Fractional Order Diffusion–Wave Equations

This paper considers boundary control of time fractional order diffusion–wave equation. Both boundary stabilization and disturbance rejection are considered. This paper, for the first time, has confirmed, via hybrid symbolic and numerical simulation studies, that the existing two schemes for boundary stabilization and disturbance rejection for (integer order) wave/beam equations are still valid for time fractional order diffusion–wave equations. The problem definition, the hybrid symbolic and numerical simulation techniques, outlines of the methods for boundary stabilization and disturbance rejection are presented together with extensive simulation results. Different dynamic behaviors are revealed for different fractional orders which may stimulate new future research opportunities.
Bilateral Pulmonary Emboli and Deep Venous Thrombi in Association With Chronic Inflammatory Demyelinating Polyneuropathy.

Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune neurological disorder primarily affecting the peripheral nervous system. It is important to recognize because treatment with immunomodulators can improve symptoms. We present the case of a 61-year-old man who developed a saddle pulmonary embolus as well as right-sided deep venous thrombi following left knee arthroplasty. Two months later, he had persistent pre-syncopal symptoms with exertion and had developed paraesthesias in both feet. Invasive cardiopulmonary exercise testing revealed preload failure with no evidence of pulmonary hypertension. He was then referred to neurology where clinical history, physical examination, autonomic battery, and nerve biopsy were consistent with a diagnosis of CIDP with autonomic dysfunction. Extensive venous thromboembolism may be a unique presentation of CIDP. The mechanisms, which may lead to hypercoagulability in CIDP, include the presence of systemic inflammation and denervation of peripheral vasculature leading to stasis.
Proficiency at Tick Identification by Pathologists and Clinicians Is Poor.

Objectives Prompt accurate identification of tick species is required for appropriate administration of single dose antimicrobial prophylaxis for Lyme disease in selected patients. To determine the proficiency of clinicians at tick identification in the northeastern United States where Lyme disease has its highest incidence, we undertook a survey. Methods We analyzed the results of a voluntary survey testing proficiency in identifying tick species using high-resolution photographs of ticks. Results Only 35% of ticks were correctly identified. Although 60% of respondents could identify a nonengorged adult blacklegged tick, only 34% could correctly identify a partially engorged blacklegged tick. Participants performed even worse at classifying brown dog, American dog, and Lone Star ticks. Conclusions Proficiency of tick identification by pathologists and clinicians is poor.
Characteristics and outcomes of patients diagnosed with DNMT3A mutated acute myeloblastic leukemia.

e19018Background: Advances in molecular profiling have identified recurring gene mutations in acute myeloid leukemia (AML) that have independent prognostic significance with several being targets f...
SafeOverPass: An Edge-Based Low-Clearance Overpass Warning System

Preventing accidents on the roads and increasing safety measures are essential to reducing traffic jams and saving lives. One of the major road accidents in the United States involves tall vehicles and overpasses. Although there are commercial truck overpass warning systems in the market, the majority of these systems include a certain percentage of overpasses that exist on predetermined truck routes and not city streets. These systems do not incorporate machine learning models that use historical driving route data to predict the next route segment a tall vehicle will be adopting. In addition, these systems require regular updates and maintenance and eventually run out of storage space. In this work, we propose SafeOverPass as a low-clearance warning system that leverages edge computing and machine learning to provide essential warning mechanism to tall vehicle drivers. Our results show that SafeOverPass can provide the driver with early low-clearance warning to prevent accidents without any hardware or software complexity for the user.
Predicting pelvic congestion syndrome: Concomitant pelvic pain diagnoses do not affect venography or embolization outcomes

Objectives: Pelvic congestion syndrome (PCS) is a challenging diagnosis to make secondary to nonspecific presenting symptoms and imaging findings. This retrospective review aims to discern predictive factors which can guide the decision to perform catheter-based venography and prognosticate outcomes. Material and Methods: A retrospective analysis of patients who underwent catheter venography for PCS between January 2014 and December 2019 was performed. Multiple factors, including patient demographics, clinical history, pre-procedural imaging, venographic findings, and treatment outcomes 180 days post-procedure, were included in the analysis. Venographic findings were used to separate patients into two groups (positive or negative), with these factors compared across groups. Regression analysis controlled for the confounding effects of age and body mass index (BMI). Treated subjects were separated based on outcome (partial, no response, complete response, or technical failure), and comparisons were performed. Results: Eighty patients were included in the initial analysis. Two patients were excluded due to prior embolization or portal hypertension. Seventy-eight patients were included in the final analysis. Sixty-two patients had positive findings, and 16 had no venographic findings to suggest PCS. A history of prior pregnancy was a significant predictor of positive venographic results (odds ratio = 5.99, P = 0.007). BMI was significantly lower in those with positive venographic results (P = 0.047). Presence of concomitant diagnoses did not affect venographic findings or treatment outcomes. No factors predicted treatment outcomes. Five of the treated patients had subsequent successful pregnancies. Conclusion: A lower BMI supports the decision to perform venography for suspected PCS. In addition, patients who carried concomitant potentially confounding diagnoses for chronic pelvic pain were found to have similar rates of venographic findings suggesting PCS, as well as similar treatment outcomes.
CamouflageFS: Increasing the Effective Key Length in Cryptographic Filesystems on the Cheap

One of the few quantitative metrics used to evaluate the security of a cryptographic file system is the key length of the encryption algorithm; larger key lengths correspond to higher resistance to brute force and other types of attacks. Since accepted cryptographic design principles dictate that larger key lengths also impose higher processing costs, increasing the security of a cryptographic file system also increases the overhead of the underlying cipher.
Classroom Culture, Mathematics Culture, and the Failures of Reform: The Need for a Collective View of Culture.

Background/ContextDespite the tremendous amount of effort devoted by many mathematics educators to promote, defend, and implement reform-based mathematics education, procedural mathematics, which l...