cssi/SciSciGPT-SciSciNet huggingface dataset:
A temperature-dependent nonlinear analytic model for AlGaN-GaN HEMTs on SiC

A temperature-dependent large-signal model for continuous-wave (CW) and pulsed-mode operation is presented and applied to aluminum gallium nitride, gallium nitride (AlGaN-GaN) high electron-mobility transistors (HEMTs) on silicon-carbide (SiC) substrates. The model includes thermal, RF dispersion, and bias-dependent capacitance model elements, and is suitable for application with a harmonic-balance simulator. Temperature- and bias-dependent on-wafer pulsed I-V and S-parameter measurements from 27/spl deg/C to 200/spl deg/C are used to examine trapping and thermal effects, and to determine temperature- and bias-dependent parameterized model coefficients for the nonlinear model. Large-signal measurement and model results are presented for 2 /spl times/ 0.35 /spl mu/m /spl times/ 125 /spl mu/m and 12 /spl times/ 0.35 /spl mu/m /spl times/ 125 /spl mu/m GaN HEMTs fabricated on SiC. The nonlinear model shows good agreement with measured CW power sweep data at an elevated temperature of 150/spl deg/C under more than 5-W power dissipation, and with measured pulsed load-pull data.
Breakdown voltage improvement in strained InGaAlAs/GaAs FETs

GaAs MESFETs with a surface layer of pseudomorphic InGaAlAs have been fabricated. The compressive strain and wide bandgap in the InGaAlAs layer reduce the impact ionization rate in this layer and improve the breakdown voltage of the device. A 1 mu m*75 mu m gate device with the pseudomorphic surface layer showed an improvement in gate-to-drain breakdown of over 55% and an improvement in channel breakdown of 50% as compared to a similar device without the pseudomorphic layer. Both devices had a peak transconductance of about 190 mS/mm and a saturation current of about 265 mA/mm. >
Persistent surveillance with a team of MAVs

In this paper, we focus on the detailing of a system architecture capable of addressing the problem of persistent surveillance with a team of autonomous micro-aerial vehicles (MAVs). We detail the problem of interest, discuss system requirements, and provide an overview of our approach. The remainder of the paper is dedicated to the system design and evaluation on a team of quadrotors in simulation and experiments.
Der gewundene Pfad zum Erythropoietin entlang der Grenze von Chemie und Biologie

Die Totalsynthese eines homogenen Erythropoietins (EPO), das die native Aminosauresequenz aufweist und Chitobioseglycane an jeder der drei N-glycosylierten Wildtyp-Stellen tragt, wurde in unserem Laboratorium erzielt. Wir beschreiben in diesem Kurzaufsatz unsere ein Jahrzehnt dauernden Forschungsbemuhungen um die Synthese dieser anspruchsvollen Zielverbindung. Entscheidend fur den Erfolg war das Zusammenspiel zwischen Biologie und Chemie, den beiden Grundpfeilern der Naturwissenschaften.
Information system model and architecture generator

The advent of integrated, shared-data systems has made it increasingly necessary to address the application development process from the architectural and manufacturing perspective rather than from a build-as-you-go job shop viewpoint. Although the Business Systems Planning (BSP) methodology provides an enterprise-wide strategic Information Systems plan, it is still at an abstraction level that leaves the traditional gap between “requirements” and implementations untouched. The Information System Model and Architecture Generator (ISMOD) tool complements and enhances BSP by mechanizing the planning process, thus providing a facility to narrow this gap by allowing orderly and consistent top-to-bottom architectural decomposition of the enterprise environment. It is an enterprise planning vehicle and not an implementation system, but it is the first critical component to support an integrated systems architecture effort. It automates and, to a large extent, formalizes a laborious requirements documentation process preceding code development, and it does this “top to bottom,” from a global, enterprise-wide, information requirements viewpoint. This paper discusses the overall architectural concepts of integrated data systems development, the place of ISMOD within it, and the specific facilities, techniques, and information provided by the system.
Failure prediction in IBM BlueGene/L event logs

In this paper, we present our effort in developing a failure prediction model based on event logs collected from IBM BlueGene/L. We first show how the event records can be converted into a data set that is appropriate for running classification techniques. Then we apply classifiers on the data, including RIPPER (a rule-based classifier), support vector machines (SVMs), a traditional Nearest Neighbor method, and a customized nearest neighbor method. We show that the customized nearest neighbor approach can outperform RIPPER and SVMs in terms of both coverage and precision. The results suggest that the customized nearest neighbor approach can be used to alleviate the impact of failures.
Real-time separation of perfusion and oxygenation signals for an implantable sensor using adaptive filtering

In this paper, an adaptive filtering algorithm to separate signals due to perfusion and oxygenation has been developed using an 810-nm source, in addition to 660-nm and 940-nm sources, as an internal reference due to its limited oxygen sensitivity. The newly developed algorithm was tested using Monte Carlo simulated data to prove the effectiveness of the 810-nm reference and adaptive algorithm. Following the simulation, an in vitro model was developed to test the algorithm that used a blood flow through system wrapped with tissue. The system had the ability to isolate the effects of perfusion and oxygenation and the algorithm accurately captured the changes in these signals with reliable consistency. Using the serosal surface of the swine jejunum, in vivo data was also taken to analyze the algorithms response to fluctuating perfusion levels like that seen in hemorrhaging or failing transplants. The algorithm was able to extract the perfusion information from the oxygenation information in this in vivo study. Overall, it was shown that an adaptive filtering algorithm using an 810-nm reference has provided a means to separate oxygenation and perfusion.
Fiber-coupled waveguides for strong resonant interactions with single semiconductor quantum dots

We investigate fiber-coupled waveguides engineered for efficient interaction with single semiconductor quantum dots, with calculated fluorescence collection > 70 % and ≈ 15 dB transmission contrast upon resonant excitation. Characterization of passive waveguides and preliminary photoluminescence measurements are presented.
Boundary Layer Temperature Profile in Diamond CVD System Using Laser-Induced Fluorescence

The gas temperature of a radio-frequency thermal plasma has been measured by laser-induced fluorescence along the axis of the plasma jet near the substrate surface. The temperature was determined from the rotational population distribution of OH radicals. From the measured temperature profile, the freestream temperature was found to be about 3400 K and the boundary layer thickness was determined to be about 1 mm. A numerical model including carbon- hydrogen-argon kinetics was used to predict species concentrations near the surface of the substrate. The results indicate that all CHn radical concentrations increase with freestream temperature for temperatures between 2500–4000 K. Of the C1 radicals, methyl has the highest concentration in this range in our system, which is consistent with other reports that methyl is an important diamond growth species.
Improving TCP-Friendly Rate Control in Wired and Wireless Networks By a Scheme Based on Wireless Signal Strength

We propose a rate control scheme developed to improve TFRC (TCP-friendly rate control) in wired and wireless networks. Next-generation wireless users will expect multimedia streams of high quality as well as high mobility that has time-varying wireless error rate. The proposed scheme is designed to meet such requirements. This is accomplished by using wireless signal strength information to improve wireless TFRC performance. Most wireless devices currently have wireless signal strength information in the driver level. In Windows XP, our scheme can be implemented by a slight modification of the TFRC algorithm in the application level through the use of WRAPI 2.0. To evaluate the performance of the proposed scheme, we simulated several cases over a wireless network via the NS-2 simulator and compared the efficiency of delivery exhibited by the proposed scheme with that of existing schemes. The proposed scheme is robust to congestion loss and wireless loss. In addition, our scheme exhibits stable performance even in time-varying wireless conditions
Microwave rotational spectroscopy: A technique for specific pollutant monitoring

The properties of microwave rotational spectroscopy that make it a promising technique for gaseous pollutant monitoring are presented. Recent advances in instrumentation and technique that have suggested feasibility of in-situ monitoring are thoroughly discussed. A laboratory model of a potentially portable Gunn-diode cavity spectrometer has been interfaced to the atmosphere by way of a multistaged membrane separator. Results of testing this system under controlled experimental conditions as a specific monitor for two common gaseous pollutants are given. Determinations of the optimum sensitivity, specificity, and stability expected for this system are dsciussed along wih considerations for its calibration.
General Hartree-Fock program

Abstract Title of program : HF86 Catalogue number : AATK Program obtainable from : CPC Program Library, Queen's University of Belfast, N. Ireland (see application from in this issue) Computer : Vax 11/780; Installation : Vanderbilt University, Nashville, TN 37235, USA Operation system : VMS Version 4.4 Programming language used : FORTRAN 77 Virtual memory : 526 kbytes No. of bits in a word : 32 Peripherals used : disk, printer, terminal No. of lines in combined program and test deck : 4167
A quantitative measure of mandibular joint dysfunction: phase plane modelling of jaw movement in man.

Summary-Jaw movement during the open-close-clench cycle was recorded using a Hall-effect generator and a small permanent magnet affixed to opposing incisor teeth. Computer programs provided graphic display of jaw-closing velocity as a function of jaw position (the phase plane) and determined the error between the experimental data and a mathematical model. A large error indicated dysfunction and predicted successful treatment by accepted occlusal therapy; a small error indicated normal function or predicted unsuccessful occlusal treatment. These oblservations suggest that phase plane modelling provides a quantitative measure of joint dysyunction that may be used in monitoring treatment progress and in separating clinically diagnosed dysfunction into two categories-one which responds to occlusal therapy, and- one which does not.
Novel Protein Arginine Methyltransferase 8 Isoform Is Essential for Cell Proliferation.

Identification of molecular mechanisms that regulate cellular replicative lifespan is needed to better understand the transition between a normal and a neoplastic cell phenotype. We have previously reported that low oxygen-mediated activity of FGF2 leads to an increase in cellular lifespan and acquisition of regeneration competence in human dermal fibroblasts (iRC cells). Though cells display a more plastic developmental phenotype, they remain non-tumorigenic when injected into SCID mice (Page et al. [2009] Cloning Stem Cells 11:417–426; Page et al. [2011] Eng Part A 17:2629–2640) allowing for investigation of mechanisms that regulate increased cellular lifespan in a non-tumorigenic system. Analysis of chromatin modification enzymes by qRT-PCR revealed a 13.3-fold upregulation of the arginine methyltransferase PRMT8 in iRC cells. Increased protein expression was confirmed in both iRC and human embryonic stem cells—the first demonstration of endogenous human PRMT8 expression outside the brain. Furthermore, iRC cells express a novel PRMT8 mRNA variant. Using siRNA-mediated knockdown we demonstrated that this novel variant was required for proliferation of human dermal fibroblasts (hDFs) and grade IV glioblastomas. PRMT8 upregulation in a non-tumorigenic system may offer a potential diagnostic biomarker and a therapeutic target for cells in pre-cancerous and cancerous states. J. Cell. Biochem. 117: 2056–2066, 2016. © 2016 Wiley Periodicals, Inc.
Effects of thin soft layers on body waves

The inability of simple layered models to fit both Rayleigh wave and Love wave data has led to the proposal of an upper mantle interleaved with thin soft horizontal layers. Since surface-wave dispersion is not sensitive to the distribution of soft material but only to the fraction of soft material a variety of models is possible. The solution to this indeterminancy is found through body-wave analysis. It is shown that body waves are dispersed according to the thinness and softness of the layers. Three models, each of which satisfy all surface-wave data, are examined. Transmission seismograms calculated for these models show one to be impossible, one improbable and the other possible. Synthesis of the seismograms is accomplished through the use of time domain theory as the complicated frequency response of the models makes a frequency oriented Haskell-Thompson approach impractical.
Storage technology

The sessions on storage provide a review of recent activity in mass storage along with an update on the several technologies which are contending for a place in the storage hierarchy. These two sessions are complemented by two sessions concerned with systems and reliability aspects. On the latter issue, the application of algebraic coding theory to both data transmission and data storage is investigated. An extensive piece of theoretical and experimental work is reported and hardware implications for mass storage are considered.
Convenient new procedures for the synthesis of ethoxythiocarbonyl derivatives of amino acids

Aus dem Xanthogenat (I) entsteht mit Chlorkohlensaureethylester (II) das Substitutionsprodukt (III), das mit weiterem (I) zum Thioanhydrid (IV) reagiert.
Do changes in patient beliefs and coping strategies predict temporomandibular disorder treatment outcomes

Abstract:Objective:This study examined the applicability of the cognitive-behavioral model for temporomandibular disorders (TMD) by determining whether changes in TMD patient pain-related beliefs and coping over the course of treatment related to improvement in symptoms and disability and whether pa
Cu-Deficiency in the p-Type Semiconductor Cu5–xTa11O30: Impact on Its Crystalline Structure, Surfaces, and Photoelectrochemical Properties

The p-type semiconductor Cu5Ta11O30 has been investigated for the effect of Cu extrusion on its crystalline structure, surface chemistry, and photoelectrochemical properties. The Cu5Ta11O30 phase was prepared in high purity using a CuCl-mediated flux synthesis route, followed by heating the products in air from 250 to 750 °C in order to investigate the effects of its reported film preparation conditions as a p-type photoelectrode. At 650 °C and higher temperatures, Cu5Ta11O30 is found to decompose into CuTa2O6 and Ta2O5. At lower temperatures of 250 to 550 °C, nanosized CuIIO surface islands and a Cu-deficient Cu5–xTa11O30 crystalline structure (i.e., x ∼ 1.8(1) after 450 °C for 3 h in air) is found by electron microscopy and Rietveld structural refinement results, respectively. Its crystalline structure exhibits a decrease in the unit cell volume with increasing reaction temperature and time, owing to the increasing removal of Cu(I) ions from its structure. The parent structure of Cu5Ta11O30 is conserved...
Research on Protecting Mechanism for Small-medium Partner's Interests

Partners in Partnership Enterprise Law are classified into large and small-medium partners.This article discusses and analyzes the fact that the interests of small-medium partners might be more possibly damaged compared with those of large partners in certain conditions.Then,by referring to regulations on protecting of small-medium shareholders' interests in oversea unlimited company and in China's Company Law,the author proposes some regulations and measures concerning the protection of small-medium partners' interests with the purpose to strengthen the stability,cohesion and competitiveness of partnership businesses,to promote their power by internal harmony and to enable them to play a better role in economic and social development of China.
N-Methyl-D-Aspartate Receptors in Opioid Dependence and Withdrawal

The etiology of neurochemical, electrophysiological and behavioral expressions that accompany, indeed define, withdrawal from dependence on opioids remains elusive. However, recent evidence has emphasized three key features of opioid withdrawal. First, increased firing rates (hyperactivity) of noradrenergic neurons in the locus ceruleus correlate strongly with behavioral signs and symptoms of withdrawal (Rasmussen et al., 1990). Second, the majority of this hyperactivity (as much as 80%) is elicited as a result of increases in afferent excitatory glutamatergic input to these neurons (Akaoka and Aston-Jones, 1991; Aston-Jones et al., 1997). Third and finally, the predominant (but not necessarily the sole) source for this excitatory input is the nucleus paragigantocellularis (PGi) in the ventrolateral medulla (Akaoka and Aston-Jones, 1991). The receptor or receptors that mediate the glutamatergic excitatory input have yet to be resolved, although the N-methyl-D-aspartate (NMDA) ionotropic glutamate subtype has been implicated. The results presented here summarize our evidence for an involvement of NMDA receptors in opioid dependence and withdrawal phenomena (Zhu and Ho, 1998; Zhu et al., 1999).
Analyzing Drum Patterns Using Conditional Deep Belief Networks.

We present a system for the high-level analysis of beatsynchronous drum patterns to be used as part of a comprehensive rhythmic understanding system. We use a multilayer neural network, which is greedily pre-trained layerby-layer using restriced Boltzmann machines (RBMs), in order to model the contextual time-sequence information of a drum pattern. For the input layer of the network, we use a conditional RBM, which has been shown to be an effective generative model of multi-dimensional sequences. Subsequent layers of the neural network can be pre-trained as conditional or standard RBMs in order to learn higherlevel rhythmic features. We show that this model can be fine-tuned in a discriminative manner to make accurate predictions about beat-measure alignment. The model generalizes well to multiple rhythmic styles due to the distributed state-space of the multi-layer neural network. In addition, the outputs of the discriminative network can serve as posterior probabilities over beat-alignment labels. These posterior probabilities can be used for Viterbi decoding in a hidden Markov model in order to maintain temporal continuity of the predicted information.
MIP Reformulation for Max-Min Problems in Two-Stage Robust SCUC

With increasing renewable penetration in power systems, considerable research efforts have been focused on how to accommodate the uncertainties from renewables in the Security-Constraint Unit Commitment (SCUC) problem. One of the candidate approaches to handling uncertainties is the two-stage Robust SCUC (RSCUC), which enables system to survive in any scenario. The survivability is guaranteed by the solution optimality of the max-min problem in the second stage. However, as the non-convex max-min problem is NP-hard, it is difficult to get the exact optimal solution in acceptable time. In this paper, we propose a new efficient formulation which recasts the max-min problem to a Mixed Integer Programming (MIP) problem using Binary Expansion (BE). The upper bound of the gap between the new MIP problem and the original max-min problem is derived. The gap, which quantifies the solution optimality of the max-min problem, is controllable. Two effective acceleration techniques are proposed to improve the performance of the MIP problem by eliminating inactive flow constraints and decomposing time-coupled uncertainty budget constraints. Accordingly, the computation burden of solving the max-min problem is reduced tremendously. The simulation results for the IEEE 118-Bus system validate and demonstrate the effectiveness of the new BE-based solution approach to the two-stage RSCUC and the acceleration techniques.
Cell swelling activates basolateral membrane Cl and K conductances in rabbit proximal tubule

The ionic basis of volume regulation was assessed in the nonperfused rabbit proximal tubule (S2 segment) by use of simultaneous measurements of tubule volume via video-optical imaging techniques and basolateral membrane voltage (Vbl) and relative ionic conductance via conventional microelectrodes. Both cell volume (9.9 +/- 0.70 nl/cm tubule length) and Vbl (-42.8 +/- 3.6 mV) remained stable in the control isotonic Ringer solution (290 mosmol/kg). When the osmolality of the bathing medium was reduced to 150 mosmol/kg, tubules swelled 72% above base line within 1 min and subsequently regulated over the course of the next 4-6 min to a steady state 20 +/- 3% above the initial base-line volume. Cell swelling was accompanied by a transient hyperpolarization of Vbl of -14.3 +/- 2.0 mV (HCO3-containing Ringer) and -10.0 +/- 0.7 mV (HCO3-free Ringer). Although the hyperpolarization was not inhibited by barium in the presence of bicarbonate buffer, addition of 2 mM Ba to a bicarbonate-free Ringer depolarized Vbl by +22 mV and abolished both the relative potassium conductance and the hyperpolarization accompanying cell swelling (delta Vbl = -4.6 +/- 0.6 mV). Furthermore, the relative conductance of K at the basolateral membrane increased from 0.16 in the isotonic control medium to 0.34 at the peak of cell swelling. Because the hyperpolarization of Vbl ensued after cells had swollen approximately 10% above base line, a modest threshold volume and time delay may be involved in triggering the volume-dependent activation of the K conductance. In parallel studies, the change in Vbl on a rapid step-change in bath Cl (49 to 4.9 mM) averaged 5.3 +/- 1.0 mV in the isotonic solution and increased to +11.3 +/- 2.1 (P less than or equal to 0.05) at the peak of cell swelling. This represented an increase in the relative Cl conductance of 0.08 to 0.20, which could only be attributed to an absolute increase in the basolateral membrane Cl conductance and not to a reduction in the other major basolateral membrane conductances. It is concluded that cell swelling results in an increase in both Cl and K conductance, which may underlie subsequent cell volume regulation.
Modalities and Data Acquisition

Acquisition modalities are the image engines in a picture archiving and communications system (PACS). Of the modality mix, radiography comprises approximately 60–70% of all studies performed in a diagnostic radiology department. Since analog screen-film recording technology is still being used in many hospitals and clinics, the implementation of a PACS for electronic image acquisition, display, and archiving is associated with the conversion of analog to digital radiography technology. But the imaging modalities are much more than radiography. Real-time digital fluoroscopy, interventional angiography, and cardiology studies are producing hundreds to thousands of images per examination. Cross-sectional imaging acquisition systems such as computed tomography (CT), magnetic resonance imaging (MRI), ultrasound (US), single-photon emission computed tomography (SPECT), and positron-emission computed tomography (PET) are expanding rapidly and are in many cases becoming the examinations of choice over projection imaging.
Prosecuting Collateral Consequences

Criminal law scholars have long agreed that prosecutors wield vast and largely unreviewable discretion in the criminal justice system. This Article argues that this discretion now extends beyond criminal penalties and broadly reaches civil public policy decisions, such as deportation and licensing. As a result of ubiquitous plea bargaining and collateral consequences — state-imposed civil penalties that are triggered by criminal convictions — prosecutors can deliberately exercise discretion to trigger or avoid important civil consequences. This aspect of prosecutorial discretion has been underexamined, partly because of a lack of awareness of collateral consequences. But as a result of important new initiatives designed to promote information about collateral consequences, prosecutors as well as defendants are becoming more likely to know that even minor convictions can trigger much more serious civil penalties. As some commentators have pointed out, prosecutors who are aware of collateral consequences may have powerful incentives to drop charges or otherwise structure pleas to minimize the likelihood of certain collateral consequences. But importantly, prosecutors also have strong structural incentives to take the opposite approach and reach pleas to maximize the likelihood of civil penalties. For some prosecutors, enforcing collateral consequences serves as an administratively efficient substitute for a criminal conviction, as a source of leverage, as a way to circumvent the requirements of criminal procedure, as a means of achieving deterrence or retribution, or as a way to promote their own public policy preferences. This Article develops an analytic framework for understanding the structural incentives that lead prosecutors to influence collateral consequences; exposes legal and ethical problems associated with plea bargaining in light of collateral consequences; and argues that collateral consequences can undermine important interests in transparency and accountability.
Bleeding Disorders Related to Lung Disease

The pulmonary circulation is arguably the most anatomically and physiologically at risk of all endothelial systems in the body to the form of vascular failure manifest as extravasation. Pulmonary hemorrhage, either in the dramatic manifestation of hemoptysis or a more silent version, is a relatively common manifestation of a host of disease processes.
Gender and History of Revolutions in Northern Africa

As the North African states of Egypt, Libya, Tunisia, Morocco, Algeria, and Sudan all struggled to achieve independence from colonial rule, women asserted their historical and civil right to participate in the achievement of national self-determination. Through political activism, participation in traditional conflict roles, and active military engagement, Muslim women were absorbed into the nationalist struggle for independence. Although their contributions were recognized, acknowledgment of women's rights was often absent from revolutionary rhetoric. Rather, gender equality goals were co-opted into a hegemonic cultural value system that sought to provide a unique identity distinct from Western colonial philosophy. Once independence had been achieved, all other social movements were required to become subservient to the primary national cause, essentially dooming each revolution to eventual failure. The key to the long-term success of any revolution is to include the rights and individual liberties of women within its ideological rhetoric and objectives, and to maintain a commitment to their inclusion in the post-revolutionary state. Keywords: colonialism; gender equality; North Africa; revolutions; women's rights
Metabolic syndrome in liver transplantation: A preoperative and postoperative concern

Background Metabolic syndrome is increasing among patients undergoing liver transplantation. Nonalcoholic steatohepatitis is a manifestation of metabolic syndrome and is an increasingly common cause of end-stage liver disease necessitating orthotopic liver transplantation. We sought to determine the effect of preoperative risk factors on the development of post-transplant metabolic syndrome, complications, readmissions, and mortality. Methods We conducted a review of 114 orthotopic liver transplantations at our institution from May 2012 to April 2014. Results Patients with (n = 19) and without (n = 95) metabolic syndrome were similar with regard to age, race, and model for end-stage liver disease at time of transplant. Donor and operative factors also were similar between the groups. Preoperative diabetes was found to be associated with an increased rate of readmission (odds ratio 3.45, P = .03). While preoperative metabolic syndrome itself was not a significant predictor of worse outcomes, postoperative metabolic syndrome was associated with significantly greater readmissions in the first year. Major predictors of new onset metabolic syndrome after orthotopic liver transplantation included preoperative diabetes and obesity (odds ratio 8.54 and odds ratio 5.49, P Conclusion Efforts to decrease the incidence of postoperative metabolic syndrome after orthotopic liver transplantation may decrease readmissions and improve outcomes, along with decreasing resource utilization.
Interrogating the Lewis Acidity of Metal Sites in Beta Zeolites with 15N Pyridine Adsorption Coupled with MAS NMR Spectroscopy.

The Lewis acidity of isolated framework metal sites in Beta zeolites was characterized with 15N isotopically labeled pyridine adsorption coupled with magic-angle spinning nuclear magnetic resonance (MAS NMR) spectroscopy. The 15N chemical shift of adsorbed pyridine was found to scale with the acid character of both Lewis (Ti, Hf, Zr, Nb, Ta, and Sn) and Bronsted (B, Ga, and Al) acidic heteroatoms. The 15N chemical shift showed a linear correlation with Mulliken electronegativity of the metal center in the order Ti < Hf < Zr < Nb < Ta < Sn < H+. Theoretical calculations using density functional theory (DFT) showed a strong correlation between experimental 15N chemical shift and the calculated metal–nitrogen bond dissociation energy, and revealed the importance of active site reorganization when determining adsorption strength. The relationships found between 15N pyridine chemical shift and intrinsic chemical descriptors of metal framework sites complement adsorption equilibrium data and provide a robust me...
Infusion of Large Number of Circulating Myeloma Cells Does Not Influence the Survival of Patients Undergoing Autologous Stem Cell Transplantation.

Abstract Abstract 1224 Poster Board I-246 Multiple myeloma (MM), is a monoclonal plasma cells disorder that constitutes 10% of all hematologic malignancies. Patients with a good performance status are usually offered high-dose therapy (HDT) followed by autologous stem-cell transplantation (ASCT). HDT/ASCT is associated with complete response (CR) rates of up to 40%. Although a significant proportion of patients have a durable response after HDT/ASCT, others relapse relatively quickly and do not appear to benefit from the procedure, which may impact the overall survival (OS) of these patients. We attempt here to define the role of infusing mobilized myeloma cells on the survival of patients undergoing ASCT. Methods After obtaining an Institutional Review Board approval, we conducted a retrospective analysis on MM patients undergoing ASCT at our center. Data of disease status, graft characteristics, and outcome were collected. As part of the flow panel used to assess the mobilized ASC, monoclonal myeloma cells were identified by gating on a population of cells that express high levels of CD38 but do not stain or weakly with CD45 (CD38+/CD45−). OS was calculated from the date of ASCT to the time of death or last contact. Survival analysis was performed using the method of Kaplan and Meier (KP). Univariate and multivariate analysis was performed using the Cox proportional hazards model. Results 349 patients underwent ASCT between January 1999 and April 2008. Complete data on autograft characteristics were available on 303 patients. The mobilization regimen was Cyclophosphamide and GCSF for the majority of the patients and GCSF for the more recent transplants. Melphalan at 200 mg/m2 was give 18 hours prior ASC infusion. In 199 patients there was no CD38+/CD45- cells detected. Among the 104 patients with evidence of CD38+/CD45- cells the range was 0.1-10.2 ×10 6 cells/kg and there was no difference in survival in this patient group compared to the group without evidence of contaminating myeloma cells (p= 0.54). Continuous variable analysis also did not reveal any relationship between the dose of CD38+/CD45- cells and survival (p=0.84). There may be a survival advantage after 40 moths for those receiving CD38+/CD45- cells, however the scientific rational is not well understood. Neither B2 microglobulin nor the numbers of plasma cells in the bone marrow were relevant in multivariate analysis (p= 0.42 and 0.13, respectively). Conclusion The presence of myeloma cells in the autograft does not appear to influence overall survival and the inclusion of CD45 and CD38 flow cytometric analysis of mobilized stem cells may not be necessary. Download : Download high-res image (86KB) Download : Download full-size image Disclosures No relevant conflicts of interest to declare.
Design and implementation of a 12 kW wind-solar distributed power and instrumentation system as an educational testbed for Electrical Engineering Technology students

The main objective of this paper is to report and present design and implementation of a 12 kW solar-wind hybrid power station and associated wireless sensors and LabView based monitoring instrumentation systems to provide a teaching and research facility on renewable energy areas for students and faculty members in Electrical Engineering Technology (EET) programs at the University of Northern Iowa (UNI). This new ongoing project requires to purchase a 10 kW Bergey Excel-S wind turbine with a Power Sink II utility intertie module (208 V/240V AC, 60 Hz), eight BP SX175B 175W solar PhotoVoltaic (PV) panels, and related power and instrumentation/data acquisition hardware. A 100 ft long wind tower to house the new wind turbine is available at UNI campus. Furthermore, the electricity generated by this power station will be used as a renewable energy input for a smart grid based green house educational demonstration project to aid the teaching and research on smart grid and energy efficiency issues. 330:038 Introduction to Electrical Power/Machinery, 330:166 Adv Electrical Power Systems, 330:059/159 Wind Energy Applications in Iowa, 330:059/159 (2) Solar Energy Applications and Issues, and 330:186 Wind Energy Management are the classes that will use this proposed testbed. There are also workshops planned for the area Science, Technology, Engineering, and Mathematics (STEM) teachers as well as local farmers' education and training on wind and solar power systems. Previous workshops organized by UNI Continuing and Distance Education have been very successful. The hybrid unit contains two complete generating plants, a wind-turbine system and a PV solar-cell plant. These sources are connected and synchronized in parallel to the UNI power grid as part of laboratory activities on wind-solar hybrid power systems and grid-tie interactions. The proposed project is part of a program initiative to improve our laboratory facilities to better reflect on the current and future renewable energy technologies. The proposed testbed will allow students to be educated and trained in the utilization of real-time electrical power systems and additionally will allow them to gain valuable “hand-on” experience in setting up a real-time data acquisition system specifically in grid-tied wind-solar power systems. Since Iowa's solar energy resources are higher in summer, this will provide an excellent complement to the load demand when summers are not windy.
Characterization of public extended enterprises: A conceptual framework

The challenges confronting public extended enterprises are increasing; both complexity and resource limitations necessitate new, more effective organizational constructs. As a path to better public...
The Enemy Within: Max Brooks’s World War Z and the Terror of Living Death

Ortolano’s consideration of the zombie aesthetics of Max Brooks’s World War Z reconceptualizes the work as an unrecognized text in the canon of post-9/11 literature. The novel terrifyingly portrays a United States that has economically and intellectually cannibalized itself and follows the decadent nation’s struggle for survival against a zombie menace, an existential threat that brings readers face to face with the unthinking humanoids that they fear they may have already become. The novel’s utopic response to this crisis (and the longing it embodies for such a catastrophe) indicates that September 11th, as disastrous as it was, failed to shake late-late capitalist America out of its deadened and corporate-induced malaise. In fact, it only helped to complete a vast American (un)death. Ultimately, the work’s longing for the rise of the living dead reveals the extent to which individuals feel alienated and dehumanized by an economic system and cultural logic that has no place for them and has failed to live up to its promises to itself or its citizens.
Performance Analysis of Opportunistic Channel Bonding in Multi-Channel WLANs

In this paper, an analytical framework is developed to study the performance of opportunistic channel bonding in IEEE 802.11 WLANs. Specifically, we consider a WLAN operating on multiple channels shared by both legacy users and IEEE 802.11ac users with channel bonding capability. By capturing the opportunistic channel bonding from the IEEE 802.11ac users in the primary channel and the random access of legacy users in the secondary channels, we derive the successful channel bonding probability, and the throughput of both legacy and IEEE 802.11ac users. Our analysis shows that with multi-channel bonding, ac users achieves a higher throughput at the cost of reduced throughput of legacy users in the secondary channels. The channel bonding achieves a higher total network throughput only when there is no legacy user in the secondary channels, and the total throughput decreases when legacy users exist due to the increased contentions in the secondary channels. The analysis provides important guidance for the deployment of multi-channel WLANs where ac users should select a proper primary channel to maximize its bonding opportunity and to attain the maximum throughput. Extensive simulations are conducted to validate the analysis.
Health and Access to Care during the First 2 Years of the ACA Medicaid Expansions

BackgroundBy September 2015, a total of 29 states and Washington, D.C., were participating in Medicaid expansions under the Affordable Care Act. We examined whether Medicaid expansions were associated with changes in insurance coverage, health care use, and health among low-income adults. MethodsWe compared changes in outcomes during the 2 years after implementation of the Medicaid expansion (2014 and 2015) relative to the 4 years before expansion (2010 through 2013) in states with and without expansions, using data from the National Health Interview Survey. The sample consisted of 60,766 U.S. citizens who were 19 to 64 years of age and had incomes below 138% of the federal poverty level. Outcomes included insurance coverage, access to and use of medical care in the past 12 months, and health status as reported by the respondents. ResultsA total of 29 states and Washington, D.C., expanded Medicaid by September 1, 2015. In year 2 after implementation, uninsurance rates were reduced in expansion states rela...
The competing effects of core rigidity and linker flexibility in the nanoassembly of trivalent small molecule-DNA hybrids (SMDH3s)-a synergistic experimental-modeling study.

The nanoassembly behavior of trivalent small molecule-DNA hybrids (SMDH3s) was investigated as a function of core geometry and supramolecular flexibility through a synergistic experimental-modeling study. While complementary SMDH3s possessing a highly flexible tetrahedral trivalent core primarily assemble into nanoscale caged dimers, the nanoassemblies of SMDH3 comonomers with rigid pyramidal and trigonal cores yield fewer caged dimers and more large-oligomer networks. Specifically, the rigid pyramidal SMDH3 comonomers tend to form smaller nanosized aggregates (dimers, tetramers, and hexamers) upon assembly, attributable to the small (<109°) branch-core-branch angle of the pyramidal core. In contrast, the more-rigid trigonal planar SMDH3 comonomers have a larger (∼120°) branch-core-branch angle, which spaces their DNA arms farther apart, facilitating the formation of larger nanoassemblies (≥nonamers). The population distributions of these nanoassemblies were successfully captured by coarse-grained molecular dynamics (CGMD) simulations over a broad range of DNA concentrations. CGMD simulations can also forecast the effect of incorporating Tn spacer units between the hydridizing DNA arms and the rigid organic cores to increase the overall flexibility of the SMDH3 comonomers. Such “decoupling” of the DNA arms from the organic core was found to result in preferential formation of nanoscale dimers up to an optimal spacer length, beyond which network formation takes over due to entropic factors. This excellent agreement between the simulation and experimental results confirms the versatility of the CGMD model as a useful and reliable tool for elucidating the nanoassembly of SMDH-based building blocks.
On certainty equivalence of demand charge reduction using storage

We investigate the problem of optimal storage control for the purpose of jointly reducing the volumetric energy charge and a whole-period relevant demand charge. We systematically investigate the structure of the optimal solution set of this storage control problem, and we for the first time establish the equivalence among the optimal solutions of the original stochastic control problem, a corresponding stochastic programming problem and its deterministic counterpart, which greatly simplifies the process of finding optimal solutions for the original problem. Based on the equivalence among different problems, we propose an algorithm to obtain an optimal solution of the stochastic control program which merely needs offline information. We validate our approach by testing on over PG&E residential customers' data and show substantial cost reduction under the tariff with both energy charge and demand charge.
Historical contingency in fluviokarst landscape evolution

Abstract Lateral and vertical erosion at meander bends in the Kentucky River gorge area has created a series of strath terraces on the interior of incised meander bends. These represent a chronosequence of fluviokarst landscape evolution from the youngest valley side transition zone near the valley bottom to the oldest upland surface. This five-part chronosequence (not including the active river channel and floodplain) was analyzed in terms of the landforms that occur at each stage or surface. These include dolines, uvalas, karst valleys, pocket valleys, unincised channels, incised channels, and cliffs (smaller features such as swallets and shafts also occur). Landform coincidence analysis shows higher coincidence indices (CI) than would be expected based on an idealized chronosequence. CI values indicate genetic relationships (common causality) among some landforms and unexpected persistence of some features on older surfaces. The idealized and two observed chronosequences were also represented as graphs and analyzed using algebraic graph theory. The two field sites yielded graphs more complex and with less historical contingency than the idealized sequence. Indeed, some of the spectral graph measures for the field sites more closely approximate a purely hypothetical no-historical-contingency benchmark graph. The deviations of observations from the idealized expectations, and the high levels of graph complexity both point to potential transitions among landform types as being the dominant phenomenon, rather than canalization along a particular evolutionary pathway. As the base level of both the fluvial and karst landforms is lowered as the meanders expand, both fluvial and karst denudation are rejuvenated, and landform transitions remain active.
Docendo Discimus: Students Learn by Teaching Peers Through Video

This study presents and evaluates a scalable approach for improving learning outcomes by having students "teach" peers in the same course via video. The approach was tested in a standard upper-level undergraduate computer algorithms course with material commonly considered challenging to teach: combinatorial optimization and NP-complete problems. An important design goal was to incentivize students to learn deeply in crafting their instructional videos while minimizing the added burden on instructors to review their products, allowing for scalability. A learning assessment administered to two successive cohorts (N=89) showed statistically significant improvement (P
Dual Tuning of Ni–Co–A (A = P, Se, O) Nanosheets by Anion Substitution and Holey Engineering for Efficient Hydrogen Evolution

Seeking earth-abundant electrocatalysts with high efficiency and durability has become the frontier of energy conversion research. Mixed-transition-metal (MTM)-based electrocatalysts, owing to the desirable electrical conductivity, synergistic effect of bimetal atoms, and structural stability, have recently emerged as new-generation hydrogen evolution reaction (HER) electrocatalysts. However, the correlation between anion species and their intrinsic electrocatalytic properties in MTM-based electrocatalysts is still not well understood. Here we present a novel approach to tuning the anion-dependent electrocatalytic characteristics in MTM-based catalyst for HER, using holey Ni/Co-based phosphides/selenides/oxides (Ni–Co–A, A = P, Se, O) as the model materials. The electrochemical results, combined with the electrical conductivity measurement and DFT calculation, reveal that P substitution could modulate the electron configuration, lower the hydrogen adsorption energy, and facilitate the desorption of hydrog...
Assessing the role of mobile learning systems in graduate management education

Mobile learning has come a long way since Sir Isaac Pitman initiated the first correspondence course in the early 1840s. The demands of globalization call for new and innovative learning systems for enhancing graduate management education. One approach for meeting these challenges is through the increased use of mobile learning systems like the iPad. The purpose of this paper is to highlight the results from an iPad initiative in a program of graduate management education. The preliminary data shows that while learning outcomes did not vary between the iPad and non-iPad sections student convenience and flexibility along with energy and environmental sustainability were enhanced.